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Stefan Fruehauf

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Giordano Frank A; Appelt Jens Uwe; Zucknick Manuela; Abba Mohammed; Zeller W Jens; Fruehauf Stefan; Allgayer Heike; Laufs Stephanie
Cold spots in hot spots: transcription start sites of active genes are spared from HIV vector integration.
Veldwijk Marlon R; Herskind Carsten; Sellner Leopold; Radujkovic Aleksandar; Laufs Stephanie; Fruehauf Stefan; Zeller W Jens; Wenz Frederik
Normal-tissue radioprotection by overexpression of the copper-zinc and manganese superoxide dismutase genes.
Odening K E; Li W; Rutz R; Laufs S; Fruehauf S; Fishelson Z; Kirschfink M
Enhanced complement resistance in drug-selected P-glycoprotein expressing multi-drug-resistant ovarian carcinoma cells.

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All Publications

2009: Giordano Frank A; Appelt Jens Uwe; Zucknick Manuela; Abba Mohammed; Zeller W Jens; Fruehauf Stefan; Allgayer Heike; Laufs Stephanie
Cold spots in hot spots: transcription start sites of active genes are spared from HIV vector integration.
AIDS (London, England) 2009;23(18):2535-7.
2009: Veldwijk Marlon R; Herskind Carsten; Sellner Leopold; Radujkovic Aleksandar; Laufs Stephanie; Fruehauf Stefan; Zeller W Jens; Wenz Frederik
Normal-tissue radioprotection by overexpression of the copper-zinc and manganese superoxide dismutase genes.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2009;185(8):517-23.
2009: Odening K E; Li W; Rutz R; Laufs S; Fruehauf S; Fishelson Z; Kirschfink M
Enhanced complement resistance in drug-selected P-glycoprotein expressing multi-drug-resistant ovarian carcinoma cells.
Clinical and experimental immunology 2009;155(2):239-48.
2008: Sellner Leopold; Stiefelhagen Marius; Kleinschmidt Jürgen A; Laufs Stephanie; Wenz Frederik; Fruehauf Stefan; Zeller W Jens; Veldwijk Marlon R
Generation of efficient human blood progenitor-targeted recombinant adeno-associated viral vectors (AAV) by applying an AAV random peptide library on primary human hematopoietic progenitor cells.
Experimental hematology 2008;36(8):957-64.
2008: Veldwijk Marlon R; Berlinghoff Simone; Jauch Anna; Laufs Stephanie; Zeller W Jens; Wenz Frederik; Fruehauf Stefan
Characterization of human mesothelioma cell lines as tumor models for suicide gene therapy.
Onkologie 2008;31(3):91-6.
2008: Maier Patrick; Herskind Carsten; Fleckenstein Katharina; Spier Isabel; Laufs Stephanie; Zeller W Jens; Fruehauf Stefan; Wenz Frederik
MDR1 gene transfer using a lentiviral SIN vector confers radioprotection to human CD34+ hematopoietic progenitor cells.
Radiation research 2008;169(3):301-10.
2008: Bleier S; Maier P; Allgayer H; Wenz F; Zeller W J; Fruehauf S; Laufs S
Multiple displacement amplification enables large-scale clonal analysis following retroviral gene therapy.
Journal of virology 2008;82(5):2448-55.
2008: Stiefelhagen Marius; Sellner Leopold; Kleinschmidt Jürgen A; Jauch Anna; Laufs Stephanie; Wenz Frederik; Zeller W Jens; Fruehauf Stefan; Veldwijk Marlon R
Application of a haematopoetic progenitor cell-targeted adeno-associated viral (AAV) vector established by selection of an AAV random peptide library on a leukaemia cell line.
Genetic vaccines and therapy 2008;6():12.
2007: Bozorgmehr Farastuk; Laufs Stefanie; Sellers Stephanie E; Roeder Ingo; Zeller Walter J; Dunbar Cynthia E; Fruehauf Stefan
No evidence of clonal dominance in primates up to 4 years following transplantation of multidrug resistance 1 retrovirally transduced long-term repopulating cells.
Stem cells (Dayton, Ohio) 2007;25(10):2610-8.
2007: Ribeiro Daniel; Veldwijk Marlon R; Benner Axel; Laufs Stephanie; Wenz Frederik; Ho Anthony D; Fruehauf Stefan
Differences in functional activity and antigen expression of granulocytes primed in vivo with filgrastim, lenograstim, or pegfilgrastim.
Transfusion 2007;47(6):969-80.
2007: Fruehauf S; Klaus J; Huesing J; Veldwijk M R; Buss E C; Topaly J; Seeger T; Zeller L W J; Moehler T; Ho A D; Goldschmidt H
Efficient mobilization of peripheral blood stem cells following CAD chemotherapy and a single dose of pegylated G-CSF in patients with multiple myeloma.
Bone marrow transplantation 2007;39(12):743-50.
2007: Fruehauf Stefan; Topaly Julian; Buss Eike C; Fischer Thomas; Ottmann Oliver G; Emmerich Bertold; Müller Martin C; Schuld Peter; Balleisen Leopold; Hehlmann Rüdiger; Ho Anthony D; Hochhaus Andreas
Imatinib combined with mitoxantrone/etoposide and cytarabine is an effective induction therapy for patients with chronic myeloid leukemia in myeloid blast crisis.
Cancer 2007;109(8):1543-9.
2007: Klaus Jens; Herrmann Doris; Breitkreutz Iris; Hegenbart Ute; Mazitschek Uta; Egerer Gerlinde; Cremer Friedrich W; Lowenthal Ray M; Huesing Johannes; Fruehauf Stefan; Moehler Thomas; Ho Anthony D; Goldschmidt Hartmut
Effect of CD34 cell dose on hematopoietic reconstitution and outcome in 508 patients with multiple myeloma undergoing autologous peripheral blood stem cell transplantation.
European journal of haematology 2007;78(1):21-8.
2007: Giordano F A; Hotz-Wagenblatt A; Lauterborn D; Appelt J-U; Fellenberg K; Nagy K Z; Zeller W J; Suhai S; Fruehauf S; Laufs S
New bioinformatic strategies to rapidly characterize retroviral integration sites of gene therapy vectors.
Methods of information in medicine 2007;46(5):542-7.
2006: Laufs Stephanie; Guenechea Guillermo; Gonzalez-Murillo Africa; Zsuzsanna Nagy K; Luz Lozano M; del Val Coral; Jonnakuty Sunitha; Hotz-Wagenblatt Agnes; Jens Zeller W; Bueren Juan A; Fruehauf Stefan
Lentiviral vector integration sites in human NOD/SCID repopulating cells.
The journal of gene medicine 2006;8(10):1197-207.
2006: Maier Patrick; Fleckenstein Katharina; Li Li; Laufs Stephanie; Zeller W Jens; Baum Christopher; Fruehauf Stefan; Herskind Carsten; Wenz Frederik
Overexpression of MDR1 using a retroviral vector differentially regulates genes involved in detoxification and apoptosis and confers radioprotection.
Radiation research 2006;166(3):463-73.
2006: Monse Hella; Laufs Stephanie; Kuate Seraphin; Zeller W Jens; Fruehauf Stefan; Uberla Klaus
Viral determinants of integration site preferences of simian immunodeficiency virus-based vectors.
Journal of virology 2006;80(16):8145-50.
2006: Fruehauf Stefan; Seeger Timon; Maier Patrick; Li Li; Weinhardt Stephan; Laufs Stephanie; Wagner Wolfgang; Eckstein Volker; Bridger Gary; Calandra Gary; Wenz Frederick; Zeller W Jens; Goldschmidt Hartmut; Ho Anthony D
The CXCR4 antagonist AMD3100 releases a subset of G-CSF-primed peripheral blood progenitor cells with specific gene expression characteristics.
Experimental hematology 2006;34(8):1052-9.
2006: Giordano F A; Fehse B; Hotz-Wagenblatt A; Jonnakuty S; del Val C; Appelt J-U; Nagy K Z; Kuehlcke K; Naundorf S; Zander A R; Zeller W J; Ho A D; Fruehauf S; Laufs S
Retroviral vector insertions in T-lymphocytes used for suicide gene therapy occur in gene groups with specific molecular functions.
Bone marrow transplantation 2006;38(3):229-35.
2006: Radujkovic Aleksandar; Topaly Julian; Fruehauf Stefan; Zeller W Jens
Combination treatment of imatinib-sensitive and -resistant BCR-ABL-positive CML cells with imatinib and farnesyltransferase inhibitors.
Anticancer research 2006;26(3A):2169-77.
2006: Bornhäuser Martin; Kröger Nicolaus; Schwerdtfeger Rainer; Schafer-Eckart Karin; Sayer Herbert G; Scheid Christoph; Stelljes Mattias; Kienast Joachim; Mundhenk Peter; Fruehauf Stefan; Kiehl Michael G; Wandt Hannes; Theuser Catrin; Ehninger Gerhard; Zander Axel R;
Allogeneic haematopoietic cell transplantation for chronic myelogenous leukaemia in the era of imatinib: a retrospective multicentre study.
European journal of haematology 2006;76(1):9-17.
2006: Buss E C; Laufs S; Naundorf S; Kuehlcke K; Nagy K Z; Zeller W J; Fruehauf S
Retroviral MDR1 gene transfer into marrow-engrafting human peripheral blood progenitor cells results in preferential transgene expression in the immature myeloid compartment rather than in mature myeloid progeny in vivo.
Cytotherapy 2006;8(6):562-9.
2005: Wagner Wolfgang; Laufs Stephanie; Blake Jonathon; Schwager Christian; Wu Xiaolin; Zeller Jens W; Ho Anthony D; Fruehauf Stefan
Retroviral integration sites correlate with expressed genes in hematopoietic stem cells.
Stem cells (Dayton, Ohio) 2005;23(8):1050-8.
2005: Fruehauf Stefan
Long awaited: CD34+ determination in steady-state hematopoiesis by real-time polymerase chain reaction.
Haematologica 2005;90(7):865A.
2005: Radujkovic A; Schad M; Topaly J; Veldwijk M R; Laufs S; Schultheis B S; Jauch A; Melo J V; Fruehauf S; Zeller W J
Synergistic activity of imatinib and 17-AAG in imatinib-resistant CML cells overexpressing BCR-ABL--Inhibition of P-glycoprotein function by 17-AAG.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(7):1198-206.
2005: Fruehauf Stefan; Seeger Timon
New strategies for mobilization of hematopoietic stem cells.
Future oncology (London, England) 2005;1(3):375-83.
2005: Fruehauf Stefan; Buss Eike C; Topaly Julian; Kreipe H H; Ho A D
Myeloablative conditioning in myelofibrosis using i.v. treosulfan and autologous peripheral blood progenitor cell transplantation with high doses of CD34+ cells results in hematologic responses - follow-up of three patients.
Haematologica 2005;90(2):ECR08.
2005: Fruehauf Stefan; Buss Eike C; Tropaly Julian; Kreipe H H; Ho A D
Myeloablative conditioning in myelofibrosis using i.v. treosulfan and autologous peripheral blood progenitor cell transplantation with high doses of CD34+ cells results in hematologic responses. A follow-up of three patients.
Haematologica 2005;90(1):ECR08.
2005: Fruehauf S; Seeger T; Topaly J
Innovative strategies for PBPC mobilization.
Cytotherapy 2005;7(5):438-46.
2005: Fruehauf S; Ho A D
New developments in stem cell biology and therapy. First meeting report from the working group of the German Society for Hematology and Oncology.
Cytotherapy 2005;7(3):301-8.
2004: Laufs Stephanie; Nagy K Zsuzsanna; Giordano Frank A; Hotz-Wagenblatt Agnes; Zeller W Jens; Fruehauf Stefan
Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(5):874-81.
2004: Berlinghoff Simone; Veldwijk Marlon R; Laufs Stephanie; Maser Hans-Peter; Jauch Anna; Wenz Frederik; Jens Zeller W; Fruehauf Stefan
Susceptibility of mesothelioma cell lines to adeno-associated virus 2 vector-based suicide gene therapy.
Lung cancer (Amsterdam, Netherlands) 2004;46(2):179-86.
2004: Veldwijk Marlon R; Herskind Carsten; Laufs Stephanie; Zeller W Jens; Fruehauf Stefan; Wenz Frederik
Recombinant adeno-associated virus 2-mediated transfer of the human superoxide-dismutase gene does not confer radioresistance on HeLa cervical carcinoma cells.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2004;72(3):341-50.
2004: Veldwijk Marlon R; Berlinghoff Simone; Laufs Stephanie; Hengge Ulrich R; Zeller W Jens; Wenz Frederik; Fruehauf Stefan
Suicide gene therapy of sarcoma cell lines using recombinant adeno-associated virus 2 vectors.
Cancer gene therapy 2004;11(8):577-84.
2004: Witzens Mathias; Moehler Thomas; Neben Kai; Fruehauf Stefan; Hartschuh Wolfgang; Ho Anthony D; Goldschmidt Hartmut
Development of leukocytoclastic vasculitis in a patient with multiple myeloma during treatment with thalidomide.
Annals of hematology 2004;83(7):467-70.
2004: Hensel Manfred; Buss Eike C; Tiemann Markus; Parwaresch Reza; Libicher Martin; Fruehauf Stefan; Ho Anthony D
Secondary follicular lymphoma of the bone, transformed into large cell lymphoma, in a patient with chronic lymphocytic leukaemia: an uncommon manifestation of Richter's syndrome.
European journal of haematology 2004;72(3):217-21.
2004: Nagy K Zsuzsanna; Laufs Stephanie; Gentner Bernhard; Naundorf Sonja; Kuehlcke Klaus; Topaly Julian; Buss Eike C; Zeller W Jens; Fruehauf Stefan
Clonal analysis of individual marrow-repopulating cells after experimental peripheral blood progenitor cell transplantation.
Stem cells (Dayton, Ohio) 2004;22(4):570-9.
2003: Fruehauf S; Veldwijk M R; Zeller W J; Laufs S
Prospects and RISC score of viral gene therapy for sarcoma.
Expert opinion on biological therapy 2003;3(8):1241-51.
2003: Müller M C; Gattermann N; Lahaye T; Deininger M W N; Berndt A; Fruehauf S; Neubauer A; Fischer T; Hossfeld D K; Schneller F; Krause S W; Nerl C; Sayer H G; Ottmann O G; Waller C; Aulitzky W; le Coutre P; Freund M; Merx K; Paschka P; König H; Kreil S; Berger U; Gschaidmeier H; Hehlmann R; Hochhaus A
Dynamics of BCR-ABL mRNA expression in first-line therapy of chronic myelogenous leukemia patients with imatinib or interferon alpha/ara-C.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(12):2392-400.
2003: Fruehauf Stefan; Seggewiss Ruth
It's moving day: factors affecting peripheral blood stem cell mobilization and strategies for improvement [corrected].
British journal of haematology 2003;122(3):360-75.
2003: Topaly Julian; Schad Moritz; Laufs Stephanie; Melo Junia V; Zeller W Jens; Fruehauf Stefan
Cross-resistance of imatinib mesylate and 17-AAG in imatinib-resistant cells that overexpress BCR-ABL.
British journal of haematology 2003;121(4):672-3.
2003: Fruehauf S; Topaly J; Schad M; Paschka P; Gschaidmeier H; Zeller W J; Hochhaus A; Ho A D
Imatinib restores expression of CD62L in BCR-ABL-positive cells.
Journal of leukocyte biology 2003;73(5):600-3.
2003: Gentner B; Laufs S; Nagy K Z; Zeller W J; Fruehauf S
Rapid detection of retroviral vector integration sites in colony-forming human peripheral blood progenitor cells using PCR with arbitrary primers.
Gene therapy 2003;10(9):789-94.
2003: Laufs S; Buss E C; Zeller W J; Fruehauf S
Transfer of drug resistance genes in hematopoietic progenitors for chemoprotection: is it still an option?
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2003;6(2):57-69.
2003: Fruehauf Stefan; Topaly Julian; Villalobos Matthias; Veldwijk Marlon R; Laufs Stephanie; Ho Anthony D
Quantitative real-time polymerase chain reaction shows that treatment with interferon reduces the initially upregulated PRV-1 expression in polycythemia vera patients.
Haematologica 2003;88(3):349-51.
2003: Laufs Stephanie; Gentner Bernhard; Nagy K Zsuzsanna; Jauch Anna; Benner Axel; Naundorf Sonja; Kuehlcke Klaus; Schiedlmeier Bernhard; Ho Anthony D; Zeller W Jens; Fruehauf Stefan
Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells.
Blood 2003;101(6):2191-8.
2003: Seggewiss Ruth; Buss Eike Christian; Herrmann Doris; Goldschmidt Hartmut; Ho Anthony Dick; Fruehauf Stefan
Kinetics of peripheral blood stem cell mobilization following G-CSF-supported chemotherapy.
Stem cells (Dayton, Ohio) 2003;21(5):568-74.
2002: Fruehauf Stefan; Topaly Julian; Buss Eike C; Schad Moritz; Goerner Martin; Zeller W Jens; Ho Anthony D
Combination of imatinib and established antileukemic treatment modalities for otherwise refractory BCR-ABL positive lymphoblastic leukemia.
Haematologica 2002;87(12):ECR38.
2002: Topaly J; Zeller W J; Fruehauf S
Combination therapy with imatinib mesylate (STI571): synopsis of in vitro studies.
British journal of haematology 2002;119(1):3-14.
2002: Laufs S; Baum C; Fruehauf S
Transplantation of human hematopoietic progenitor cells transduced with a retroviral vector containing the human multidrug-resistance-1 gene for myeloprotective gene therapy.
Transplantation proceedings 2002;34(6):2325-9.
2002: Veldwijk Marlon R; Topaly Julian; Laufs Stephanie; Hengge Ulrich R; Wenz Frederik; Zeller W Jens; Fruehauf Stefan
Development and optimization of a real-time quantitative PCR-based method for the titration of AAV-2 vector stocks.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(2):272-8.
2002: Topaly J; Fruehauf S; Ho A D; Zeller W J
Rationale for combination therapy of chronic myelogenous leukaemia with imatinib and irradiation or alkylating agents: implications for pretransplant conditioning.
British journal of cancer 2002;86(9):1487-93.
2002: Fruehauf S; Srbic K; Seggewiss R; Topaly J; Ho A D
Functional characterization of podia formation in normal and malignant hematopoietic cells.
Journal of leukocyte biology 2002;71(3):425-32.
2002: Perz Jolanta; Topaly Julian; Fruehauf Stefan; Hensel Manfred; Ho Anthony D
Level of CD 20-expression and efficacy of rituximab treatment in patients with resistant or relapsing B-cell prolymphocytic leukemia and B-cell chronic lymphocytic leukemia.
Leukemia & lymphoma 2002;43(1):149-51.
2002: Schiedlmeier Bernd; Schilz Andrea J; Kühlcke Klaus; Laufs Stephanie; Baum Christopher; Zeller W Jens; Eckert Hans-Georg; Fruehauf Stefan
Multidrug resistance 1 gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice.
Human gene therapy 2002;13(2):233-42.
2002: Fruehauf S; Veldwijk M R; Berlinghoff S; Basara N; Baum C; Flasshove M; Hegewisch-Becker S; Kröger N; Licht T; Moritz T; Hengge U R; Zeller W J; Laufs S
Gene therapy for sarcoma.
Cells, tissues, organs 2002;172(2):133-44.
2001: Buss E C; Schiedlmeier B; Ho A D; Zeller W J; Fruehauf S
The FBMD-1 stroma cell line secretes a unique moiety which can increase retroviral transduction of lineage-committed and primitive human peripheral blood progenitor cells.
Cancer gene therapy 2001;8(6):440-9.
2001: Fruehauf S; Steiger S; Topaly J; Ho A D
Pulmonary artery hypertension during interferon-alpha therapy for chronic myelogenous leukemia.
Annals of hematology 2001;80(5):308-10.
2001: Topaly J; Zeller W J; Fruehauf S
Synergistic activity of the new ABL-specific tyrosine kinase inhibitor STI571 and chemotherapeutic drugs on BCR-ABL-positive chronic myelogenous leukemia cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(3):342-7.
2001: Knipper R; Kuehlcke K; Schiedlmeier B; Hildinger M; Lindemann C; Schilz A J; Fauser A A; Fruehauf S; Zeller W J; Ostertag W; Eckert H G; Baum C
Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells.
Gene therapy 2001;8(3):239-46.
2000: Schilz A J; Schiedlmeier B; Kühlcke K; Fruehauf S; Lindemann C; Zeller W J; Grez M; Fauser A A; Baum C; Eckert H G
MDR1 gene expression in NOD/SCID repopulating cells after retroviral gene transfer under clinically relevant conditions.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(6):609-18.
2000: Wenz F; Steinvorth S; Lohr F; Fruehauf S; Wildermuth S; van Kampen M; Wannenmacher M
Prospective evaluation of delayed central nervous system (CNS) toxicity of hyperfractionated total body irradiation (TBI).
International journal of radiation oncology, biology, physics 2000;48(5):1497-501.
2000: Schiedlmeier B; Wermann K; Kühlcke K; Eckert H G; Baum C; Fruehauf S; Zeller W J
Human multidrug resistance-1 gene transfer to long-term repopulating human mobilized peripheral blood progenitor cells.
Bone marrow transplantation 2000;25 Suppl 2():S118-24.
2000: Veldwijk M R; Fruehauf S; Schiedlmeier B; Kleinschmidt J A; Zeller W J
Differential expression of a recombinant adeno-associated virus 2 vector in human CD34+ cells and breast cancer cells.
Cancer gene therapy 2000;7(4):597-604.
2000: Schiedlmeier B; Kühlcke K; Eckert H G; Baum C; Zeller W J; Fruehauf S
Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice.
Blood 2000;95(4):1237-48.
2000: Peper M; Steinvorth S; Schraube P; Fruehauf S; Haas R; Kimmig B N; Lohr F; Wenz F; Wannenmacher M
Neurobehavioral toxicity of total body irradiation: a follow-up in long-term survivors.
International journal of radiation oncology, biology, physics 2000;46(2):303-11.
1999: Veldwijk M R; Schiedlmeier B; Kleinschmidt J A; Zeller W J; Fruehauf S
Superior gene transfer into solid tumour cells than into human mobilised peripheral blood progenitor cells using helpervirus-free adeno-associated viral vector stocks.
European journal of cancer (Oxford, England : 1990) 1999;35(7):1136-42.
1999: Schiedlmeier B; Buss E C; Veldwijk M R; Zeller W J; Fruehauf S
Soluble bone marrow stroma factors improve the efficiency of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells.
Human gene therapy 1999;10(9):1443-52.
1999: Fruehauf S; Schmitt K; Veldwijk M R; Topaly J; Benner A; Zeller W J; Ho A D; Haas R
Peripheral blood progenitor cell (PBPC) counts during steady-state haemopoiesis enable the estimation of the yield of mobilized PBPC after granulocyte colony-stimulating factor supported cytotoxic chemotherapy: an update on 100 patients.
British journal of haematology 1999;105(3):786-94.
1999: Kasper B; Fruehauf S; Schiedlmeier B; Buchdunger E; Ho A D; Zeller W J
Favorable therapeutic index of a p210(BCR-ABL)-specific tyrosine kinase inhibitor; activity on lineage-committed and primitive chronic myelogenous leukemia progenitors.
Cancer chemotherapy and pharmacology 1999;44(5):433-8.
1999: Hundsdörfer P; Fruehauf S; Haberkorn M; Höft R; Haas R; Zeller W J
Comparison of different lymphoma cell purging modalities: An experimental study with K422 lymphoma cells.
Acta haematologica 1999;101(4):185-92.
1998: Martin-Murea S; Voso M T; Hohaus S; Pförsich M; Fruehauf S; Goldschmidt H; Hegenbart U; Haas R
The dose of granulocyte colony-stimulating factor administered following cytotoxic chemotherapy is not related to the rebound level of circulating CD34+ haemopoietic progenitor cells during marrow recovery.
British journal of haematology 1998;101(3):582-5.
1998: Fruehauf S; Veldwijk M R; Krämer A; Haas R; Zeller W J
Delineation of cell cycle state and correlation to adhesion molecule expression of human CD34+ cells from steady-state bone marrow and peripheral blood mobilized following G-CSF-supported chemotherapy.
Stem cells (Dayton, Ohio) 1998;16(4):271-9.
1998: Fruehauf S; Wermann K; Buss E C; Hundsdoerfer P; Veldwijk M R; Haas R; Zeller W J
Protection of hematopoietic stem cells from chemotherapy-induced toxicity by multidrug-resistance 1 gene transfer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;144():93-115.
1996: Wermann K; Fruehauf S; Haas R; Zeller W J
Human-mouse xenografts in stem cell research.
Journal of hematotherapy 1996;5(4):379-90.
1996: Murea S; Fruehauf S; Zeller W J; Haas R
Granulocytes harvested following G-CSF-enhanced leukocyte recovery retain their functional capacity during in vitro culture for 72 hours.
Journal of hematotherapy 1996;5(4):351-7.
1996: Fruehauf S; Breems D A; Knaän-Shanzer S; Brouwer K B; Haas R; Löwenberg B; Nooter K; Ploemacher R E; Valerio D; Boesen J J
Frequency analysis of multidrug resistance-1 gene transfer into human primitive hematopoietic progenitor cells using the cobblestone area-forming cell assay and detection of vector-mediated P-glycoprotein expression by rhodamine-123.
Human gene therapy 1996;7(10):1219-31.
1995: Fruehauf S; Boesen J J; Breems D A; Höft R; Hundsdörfer P; Zeller W J; Löwenberg B; Ploemacher R E; Haas R; Valerio D
Retroviral transfer of the multidrug resistance-1 gene into lineage-committed and primitive hemopoietic cells.
Stem cells (Dayton, Ohio) 1995;13 Suppl 3():93-9.
1995: Haas R; Witt B; Möhle R; Goldschmidt H; Hohaus S; Fruehauf S; Wannenmacher M; Hunstein W
Sustained long-term hematopoiesis after myeloablative therapy with peripheral blood progenitor cell support.
Blood 1995;85(12):3754-61.
1995: Fruehauf S; Haas R; Conradt C; Murea S; Witt B; Möhle R; Hunstein W
Peripheral blood progenitor cell (PBPC) counts during steady-state hematopoiesis allow to estimate the yield of mobilized PBPC after filgrastim (R-metHuG-CSF)-supported cytotoxic chemotherapy.
Blood 1995;85(9):2619-26.
1995: Haas R; Möhle R; Pförsich M; Fruehauf S; Witt B; Goldschmidt H; Hunstein W
Blood-derived autografts collected during granulocyte colony-stimulating factor-enhanced recovery are enriched with early Thy-1+ hematopoietic progenitor cells.
Blood 1995;85(7):1936-43.
1994: Möhle R; Pförsich M; Fruehauf S; Witt B; Krämer A; Haas R
Filgrastim post-chemotherapy mobilizes more CD34+ cells with a different antigenic profile compared with use during steady-state hematopoiesis.
Bone marrow transplantation 1994;14(5):827-32.
1994: Fruehauf S; Haas R; Zeller W J; Hunstein W
CD34 selection for purging in multiple myeloma and analysis of CD34+ B cell precursors.
Stem cells (Dayton, Ohio) 1994;12(1):95-102.
1993: Fruehauf S; Fiehn C; Haas R; Doehner H; Hunstein W
Sustained remission of idiopathic hypereosinophilic syndrome following alpha-interferon therapy.
Acta haematologica 1993;89(2):91-3.

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