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Marcus Fruttiger

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Claudio A Franco; Marcus Fruttiger; Jacqueline Gao-Li; Holger Gerhardt; Natalia Kazakova; Irene M Aspalter; Jocelyne Blanc; Raquel Blanco; Nicolas Diguet; Mathias Mericskay; Elena Mylonas; Ara Parlakian; Virginie Penard-Lacronique; Ian Rosewell; Anne Vaahtokari; Zhenlin Li
SRF selectively controls tip cell invasive behavior in angiogenesis.
Alessandro Fantin; Marcus Fruttiger; Alice Plein; Jeffrey W Pollard; Laura Denti; Joaquim Miguel Vieira; Christiana Ruhrberg
NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis.
Dawn A Sim; Javier Zarranz-Ventura; Catherine A Egan; Marcus Fruttiger; Simon Fung; Pearse A Keane; Hemal Mehta; Praveen J Patel; Adnan Tufail
Repeatability and reproducibility of choroidal vessel layer measurements in diabetic retinopathy using enhanced depth optical coherence tomography.

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2013: Claudio A Franco; Marcus Fruttiger; Jacqueline Gao-Li; Holger Gerhardt; Natalia Kazakova; Irene M Aspalter; Jocelyne Blanc; Raquel Blanco; Nicolas Diguet; Mathias Mericskay; Elena Mylonas; Ara Parlakian; Virginie Penard-Lacronique; Ian Rosewell; Anne Vaahtokari; Zhenlin Li
SRF selectively controls tip cell invasive behavior in angiogenesis.
Development (Cambridge, England) 2013;140(11):2321-33.
2013: Alessandro Fantin; Marcus Fruttiger; Alice Plein; Jeffrey W Pollard; Laura Denti; Joaquim Miguel Vieira; Christiana Ruhrberg
NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis.
Blood 2013;121(12):2352-62.
2013: Dawn A Sim; Javier Zarranz-Ventura; Catherine A Egan; Marcus Fruttiger; Simon Fung; Pearse A Keane; Hemal Mehta; Praveen J Patel; Adnan Tufail
Repeatability and reproducibility of choroidal vessel layer measurements in diabetic retinopathy using enhanced depth optical coherence tomography.
Investigative ophthalmology & visual science 2013;54(4):2893-901.
2013: Dawn A Sim; Adnan Tufail; Javier Zarranz-Ventura; Catey V Bunce; Marcus Fruttiger; Simon Fung; Pearse A Keane; Praveen J Patel; Elise Platteau; Michael B Powner; Catherine A Egan
The effects of macular ischemia on visual acuity in diabetic retinopathy.
Investigative ophthalmology & visual science 2013;54(3):2353-60.
2012: Weiyong Shen; Larry S Sherman; Ling Zhu; Murray Killingsworth; Joshua K Kirk; SoRa Lee; Nigel L Barnett; Sook H Chung; Nathan J Coorey; Marcus Fruttiger; Mark C Gillies
Conditional Müllercell ablation causes independent neuronal and vascular pathologies in a novel transgenic model.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(45):15715-27.
2012: Marco Reis; Sascha Seidel; Makoto M Taketo; Sonja Thom; Nicole Ziegler; Jenny Zinke; Ernesto Bockamp; Cathrin J Czupalla; Kavi Devraj; Stefanie Dimmeler; Marcus Fruttiger; Rosario Heck; Jadranka Macas; Karl H Plate; Stefan Liebner
Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression.
The Journal of experimental medicine 2012;209(9):1611-27.
2012: Clemens A K Lange; Ulrich F O Luhmann; Patrick H Maxwell; Freya M Mowat; Michael B Powner; Haroon Sayed; Alexander J Smith; Jane C Sowden; Emma L West; Sabu Abrahams; Robin R Ali; Marcus Fruttiger; Anastasios Georgiadis; J W B Bainbridge
Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development.
Development (Cambridge, England) 2012;139(13):2340-50.
2012: Michael B Powner; Kristis Vevis; Pranita Gandhi; Shalini Jadeja; Jenny A G McKenzie; Marcus Fruttiger
Visualization of gene expression in whole mouse retina by in situ hybridization.
Nature protocols 2012;7(6):1086-96.
2012: Alice C L Len; Michael B Powner; Xiaomin Song; Ling Zhu; Marcus Fruttiger; Gregory S Hageman; Mark C Gillies
Pilot application of iTRAQ to the retinal disease Macular Telangiectasia.
Journal of proteome research 2012;11(2):537-53.
2012: Kathleen R Allinson; Marcus Fruttiger; Hye Shin Lee; Joseph McCarty; Joseph H McCarty; Helen M Arthur
Endothelial expression of TGFβ type II receptor is required to maintain vascular integrity during postnatal development of the central nervous system.
PloS one 2012;7(6):e39336.
2011: Tuomas Tammela; Denis Tvorogov; Seppo Ylä-Herttuala; Georgia Zarkada; Wei Zheng; Evelyn Aranda; Anne Eichmann; Claudio A Franco; Marcus Fruttiger; Holger Gerhardt; Krista Heinolainen; Lars Jakobsson; Taija Mäkinen; Naoyuki Miura; Aino Murtomäki; Harri Nurmi; Jeffrey W Pollard; Kari Alitalo
VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.
Nature cell biology 2011;13(10):1202-13.
2011: Michael B Powner; Andrew Scott; Meidong Zhu; Alexander J E Foss; Mark C Gillies; Gregory S Hageman; Peter M G Munro; Marcus Fruttiger
Basement membrane changes in capillaries of the ageing human retina.
The British journal of ophthalmology 2011;95(9):1316-22.
2010: Michael B Powner; Mark C Gillies; Marina Tretiach; Andrew Scott; Robyn H Guymer; Gregory S Hageman; Marcus Fruttiger
Perifoveal müller cell depletion in a case of macular telangiectasia type 2.
Ophthalmology 2010;117(12):2407-16.
2010: Frank Kuhnert; Michael R Mancuso; Amir Shamloo; Hsiao-Ting Wang; Vir Choksi; Mareike Florek; Hua Su; Marcus Fruttiger; William L Young; Sarah C Heilshorn; Calvin J Kuo
Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124.
Science (New York, N.Y.) 2010;330(6006):985-9.
2010: Marwa Mahmoud; Kathleen R Allinson; Zhenhua Zhai; Rachael Oakenfull; Pranita Ghandi; Ralf H Adams; Marcus Fruttiger; Helen M Arthur
Pathogenesis of arteriovenous malformations in the absence of endoglin.
Circulation research 2010;106(8):1425-33.
2010: Nancy L Parmalee; Carl Schubert; Joanna E Merriam; Kaija Allikmets; Alan C Bird; Mark C Gillies; Tunde Peto; Maria Figueroa; Martin Friedlander; Marcus Fruttiger; John Greenwood; Stephen E Moss; Lois E H Smith; Carmel Toomes; Chris F Inglehearn; Rando Allikmets
Analysis of candidate genes for macular telangiectasia type 2.
Molecular vision 2010;16():2718-26.
2010: Andrew Scott; Michael B Powner; Pranita Gandhi; Claire Clarkin; David H Gutmann; Randall S Johnson; Napoleone Ferrara; Marcus Fruttiger
Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature.
PloS one 2010;5(7):e11863.
2010: Gabriela D'Amico; Stephen D Robinson; Mitchel Germain; Louise E Reynolds; Gareth J Thomas; George Elia; Garry Saunders; Marcus Fruttiger; Victor Tybulewicz; Georgia Mavria; Kairbaan M Hodivala-Dilke
Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent.
PloS one 2010;5(3):e9766.
2009: Rebecca Longbottom; Marcus Fruttiger; Ron H Douglas; Juan Pedro Martinez-Barbera; John Greenwood; Stephen E Moss
Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(44):18728-33.
2009: Rui Benedito; Cristina Roca; Inga Sörensen; Susanne Adams; Achim Gossler; Marcus Fruttiger; Ralf H Adams
The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis.
Cell 2009;137(6):1124-35.
2008: Stefan Liebner; Monica Corada; Thorsten Bangsow; Jane Babbage; Andrea Taddei; Cathrin J Czupalla; Marco Reis; Angelina Felici; Hartwig Wolburg; Marcus Fruttiger; Makoto M Taketo; Harald von Melchner; Karl H Plate; Holger Gerhardt; Elisabetta Dejana
Wnt/beta-catenin signaling controls development of the blood-brain barrier.
The Journal of cell biology 2008;183(3):409-17.
2008: Suzanne Claxton; Vassiliki Kostourou; Shalini Jadeja; Pierre Chambon; Kairbaan Hodivala-Dilke; Marcus Fruttiger
Efficient, inducible Cre-recombinase activation in vascular endothelium.
Genesis (New York, N.Y. : 2000) 2008;46(2):74-80.
2007: Adam C Vana; Nicole C Flint; Norah E Harwood; Tuan Q Le; Marcus Fruttiger; Regina C Armstrong
Platelet-derived growth factor promotes repair of chronically demyelinated white matter.
Journal of neuropathology and experimental neurology 2007;66(11):975-88.
2007: Marcus Fruttiger
Development of the retinal vasculature.
Angiogenesis 2007;10(2):77-88.
2005: Merja Hurskainen; Lauri Eklund; Pasi O Hägg; Marcus Fruttiger; Raija Sormunen; Mika Ilves; Taina Pihlajaniemi
Abnormal maturation of the retinal vasculature in type XVIII collagen/endostatin deficient mice and changes in retinal glial cells due to lack of collagen types XV and XVIII.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(11):1564-6.
2005: Suzanne Claxton; Marcus Fruttiger
Oxygen modifies artery differentiation and network morphogenesis in the retinal vasculature.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;233(3):822-8.
2005: Heloise West; William D Richardson; Marcus Fruttiger
Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes.
Development (Cambridge, England) 2005;132(8):1855-62.
2004: Suzanne Claxton; Marcus Fruttiger
Periodic Delta-like 4 expression in developing retinal arteries.
Gene expression patterns : GEP 2004;5(1):123-7.
2004: Rachel H Woodruff; Marcus Fruttiger; William D Richardson; Robin J M Franklin
Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination.
Molecular and cellular neurosciences 2004;25(2):252-62.
2003: Suzanne Claxton; Marcus Fruttiger
Role of arteries in oxygen induced vaso-obliteration.
Experimental eye research 2003;77(3):305-11.
2003: Holger Gerhardt; Matthew Golding; Marcus Fruttiger; Christiana Ruhrberg; Andrea Lundkvist; Alexandra Abramsson; Michael Jeltsch; Christopher Mitchell; Kari Alitalo; David T Shima; Christer Betsholtz
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia.
The Journal of cell biology 2003;161(6):1163-77.
2002: Ingeborg Stalmans; Yin-Shan Ng; Richard M Rohan; Marcus Fruttiger; Ann Bouché; Ali Yuce; Hajime Fujisawa; Bart Hermans; Moshe Shani; Sandra Jansen; Daniel J Hicklin; David J Anderson; Tom Gardiner; Hans-Peter Hammes; Lieve Moons; Mieke Dewerchin; Désiré Collen; Peter Carmeliet; Patricia A D'Amore
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms.
The Journal of clinical investigation 2002;109(3):327-36.
2002: Marcus Fruttiger
Development of the mouse retinal vasculature: angiogenesis versus vasculogenesis.
Investigative ophthalmology & visual science 2002;43(2):522-7.
2000: Marcus Fruttiger; Andy Robert Calver; William D Richardson
Platelet-derived growth factor is constitutively secreted from neuronal cell bodies but not from axons.
Current biology : CB 2000;10(20):1283-6.
1999: Marcus Fruttiger; Linda Karlsson; AC Hall; Alexandra Abramsson; Andy Robert Calver; Hans Boström; K Willetts; C H Bertold; JK Heath; Christer Betsholtz; William D Richardson
Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice.
Development (Cambridge, England) 1999;126(3):457-67.