FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Benjamin Frydman

Research Profile

Chemicals & Drugs

Living Beings

Rats
Mouse

Concepts & Ideas

Anatomy

Physiology

Cell Divisions

Phenomena

Procedures

Drug Screening Assays, Antitumor

Disorders

Prostatic Neoplasms

Co-author Network

Publications

TOP 3
Nigel Yarlett; Gang Wu; W Ray Waters; James A Harp; Michael J Wannemuehler; Mary Morada; Demos Athanasopoulos; Martha P Martinez; Steve J Upton; Laurence J Marton; Benjamin Frydman
Cryptosporidium parvum spermidine/spermine N1-acetyltransferase exhibits different characteristics from the host enzyme.
Nigel Yarlett; W Ray Waters; James A Harp; Michael J Wannemuehler; Mary Morada; Josephine Bellcastro; Steve J Upton; Laurence J Marton; Benjamin Frydman
Activities of DL-alpha-difluoromethylarginine and polyamine analogues against Cryptosporidium parvum infection in a T-cell receptor alpha-deficient mouse model.
Sigrid C Roberts; Yuqui Jiang; Judith E Gasteier; Benjamin Frydman; Laurence J Marton; Olle Heby; Buddy Ullman
Leishmania donovani polyamine biosynthetic enzyme overproducers as tools to investigate the mode of action of cytotoxic polyamine analogs.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Benjamin Frydman (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2007: Nigel Yarlett; Gang Wu; W Ray Waters; James A Harp; Michael J Wannemuehler; Mary Morada; Demos Athanasopoulos; Martha P Martinez; Steve J Upton; Laurence J Marton; Benjamin Frydman
Cryptosporidium parvum spermidine/spermine N1-acetyltransferase exhibits different characteristics from the host enzyme.
Molecular and biochemical parasitology 2007;152(2):170-80.
2007: Nigel Yarlett; W Ray Waters; James A Harp; Michael J Wannemuehler; Mary Morada; Josephine Bellcastro; Steve J Upton; Laurence J Marton; Benjamin Frydman
Activities of DL-alpha-difluoromethylarginine and polyamine analogues against Cryptosporidium parvum infection in a T-cell receptor alpha-deficient mouse model.
Antimicrobial agents and chemotherapy 2007;51(4):1234-9.
2007: Sigrid C Roberts; Yuqui Jiang; Judith E Gasteier; Benjamin Frydman; Laurence J Marton; Olle Heby; Buddy Ullman
Leishmania donovani polyamine biosynthetic enzyme overproducers as tools to investigate the mode of action of cytotoxic polyamine analogs.
Antimicrobial agents and chemotherapy 2007;51(2):438-45.
2006: Martina Holst; Benjamin Frydman; Laurence J Marton; Stina Oredsson
Differential polyamine analogue effects in four human breast cancer cell lines.
Toxicology 2006;223(1-2):71-81.
2005: Raquel Lima e Silva; Yoshitsugu Saishin; Yumiko Saishin; Hideo Akiyama; Shu Kachi; Sadia Aslam; Brian Rogers; Tye Deering; Yuan Yuan Gong; Sean F Hackett; Hong Lai; Benjamin Frydman; Aldonia Valasinas; Laurence J Marton; Peter A Campochiaro
Suppression and regression of choroidal neovascularization by polyamine analogues.
Investigative ophthalmology & visual science 2005;46(9):3323-30.
2005: Yanlin Wang; Amy Hacker; Tracy Murray-Stewart; Benjamin Frydman; Aldonia Valasinas; Alison V Fraser; Patrick M Woster; Robert A Casero
Properties of recombinant human N1-acetylpolyamine oxidase (hPAO): potential role in determining drug sensitivity.
Cancer chemotherapy and pharmacology 2005;56(1):83-90.
2005: Robert A Casero; Benjamin Frydman; Tracy Murray-Stewart; Patrick M Woster
Significance of targeting polyamine metabolism as an antineoplastic strategy: unique targets for polyamine analogues.
Proceedings of the Western Pharmacology Society 2005;48():24-30.
2004: John L A Mitchell; Carrie L Simkus; Thynn K Thane; Phil Tokarz; Michelle M Bonar; Benjamin Frydman; Aldonia Valasinas; Venudhar Reddy; Laurence J Marton
Antizyme induction mediates feedback limitation of the incorporation of specific polyamine analogues in tissue culture.
The Biochemical journal 2004;384(Pt 2):271-9.
2004: Cyrus J Bacchi; Donna Rattendi; Evangeline Faciane; Nigel Yarlett; Louis M Weiss; Benjamin Frydman; Patrick M Woster; Benjamin Wei; Laurence J Marton; Murray Wittner
Polyamine metabolism in a member of the phylum Microspora (Encephalitozoon cuniculi): effects of polyamine analogues.
Microbiology (Reading, England) 2004;150(Pt 5):1215-24.
2004: Benjamin Frydman; Subhra Bhattacharya; Aparajita Sarkar; Konstantin Drandarov; Serge Chesnov; Armin Guggisberg; Kasim Popaj; Sergey Sergeyev; Aysil Yurdakul; Manfred Hesse; Hirak S Basu; Laurence J Marton
Macrocyclic polyamines deplete cellular ATP levels and inhibit cell growth in human prostate cancer cells.
Journal of medicinal chemistry 2004;47(4):1051-9.
2004: Yi Huang; Judith C Keen; Erin R Hager; Renee Smith; Amy Hacker; Benjamin Frydman; Aldonia Valasinas; Venudhar Reddy; Laurence J Marton; Robert A Casero; Nancy E Davidson
Regulation of polyamine analogue cytotoxicity by c-Jun in human MDA-MB-435 cancer cells.
Molecular cancer research : MCR 2004;2(2):81-8.
2003: Wendy Devereux; Yanlin Wang; Tracy Murray-Stewart; Amy Hacker; Renee Smith; Benjamin Frydman; Aldonia Valasinas; Venudhar Reddy; Laurence J Marton; Tracey D Ward; Patrick M Woster; Robert A Casero
Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells.
Cancer chemotherapy and pharmacology 2003;52(5):383-90.
2003: Benjamin Frydman; Andrei V Blokhin; Sara Brummel; George Wilding; Yulia Maxuitenko; Aparajita Sarkar; Subhra Bhattacharya; Dawn Church; Venudhar Reddy; John A Kink; Laurence J Marton; Aldonia Valasinas; Hirak S Basu
Cyclopropane-containing polyamine analogues are efficient growth inhibitors of a human prostate tumor xenograft in nude mice.
Journal of medicinal chemistry 2003;46(21):4586-600.
2003: Aldonia Valasinas; Venudhar Reddy; Andrei V Blokhin; Hirak S Basu; Subhra Bhattacharya; Aparajita Sarkar; Laurence J Marton; Benjamin Frydman
Long-chain polyamines (oligoamines) exhibit strong cytotoxicities against human prostate cancer cells.
Bioorganic & medicinal chemistry 2003;11(18):4121-31.
2003: Yi Huang; Erin R Hager; Dawn L Phillips; Valerie R Dunn; Amy Hacker; Benjamin Frydman; John A Kink; Aldonia Valasinas; Venudhar Reddy; Laurence J Marton; Robert A Casero; Nancy E Davidson
A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2769-77.
2003: Benjamin Frydman; Carl W Porter; Yulia Maxuitenko; Aparajita Sarkar; Subhra Bhattacharya; Aldonia Valasinas; Venudhar Reddy; Nicholas Kisiel; Laurence J Marton; Hirak S Basu
A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice.
Cancer chemotherapy and pharmacology 2003;51(6):488-92.
2003: Yanlin Wang; Tracy Murray-Stewart; Wendy Devereux; Amy Hacker; Benjamin Frydman; Patrick M Woster; Robert A Casero
Properties of purified recombinant human polyamine oxidase, PAOh1/SMO.
Biochemical and biophysical research communications 2003;304(4):605-11.
2002: John L A Mitchell; Aviva Leyser; Michelle S Holtorff; Jill S Bates; Benjamin Frydman; Aldonia Valasinas; Venudhar Reddy; Laurence J Marton
Antizyme induction by polyamine analogues as a factor of cell growth inhibition.
The Biochemical journal 2002;366(Pt 2):663-71.
2002: Cyrus J Bacchi; Louis M Weiss; Schennella Lane; Benjamin Frydman; Aldonia Valasinas; Venudhar Reddy; Jerry S Sun; Laurence J Marton; Imitiaz A Khan; Magali Moretto; Nigel Yarlett; Murray Wittner
Novel synthetic polyamines are effective in the treatment of experimental microsporidiosis, an opportunistic AIDS-associated infection.
Antimicrobial agents and chemotherapy 2002;46(1):55-61.
2001: Venudhar Reddy; Aparajita Sarkar; Aldonia Valasinas; Laurence J Marton; Hirak S Basu; Benjamin Frydman
cis-Unsaturated analogues of 3,8,13,18,23-pentaazapentacosane (BE-4-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cell lines.
Journal of medicinal chemistry 2001;44(3):404-17.
2001: Aldonia Valasinas; Aparajita Sarkar; Venudhar Reddy; Laurence J Marton; Hirak S Basu; Benjamin Frydman
Conformationally restricted analogues of 1N,14N-bisethylhomospermine (BE-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cells.
Journal of medicinal chemistry 2001;44(3):390-403.
2001: Cyrus J Bacchi; D Orozco; Louis M Weiss; Benjamin Frydman; Aldonia Valasinas; Nigel Yarlett; Laurence J Marton; Murray Wittner
SL-11158, a synthetic oligoamine, inhibits polyamine metabolism of Encephalitozoon cuniculi.
The Journal of eukaryotic microbiology 2001;Suppl():92S-94S.
2000: W Ray Waters; Benjamin Frydman; Laurence J Marton; Aldonia Valasinas; Venudhar Reddy; James A Harp; Michael J Wannemuehler; Nigel Yarlett
[(1)N,(12)N]Bis(Ethyl)-cis-6,7-dehydrospermine: a new drug for treatment and prevention of Cryptosporidium parvum infection of mice deficient in T-cell receptor alpha.
Antimicrobial agents and chemotherapy 2000;44(10):2891-4.
1998: Venudhar Reddy; Aldonia Valasinas; Aparajita Sarkar; Hirak S Basu; Laurence J Marton; Benjamin Frydman
Conformationally restricted analogues of 1N,12N-bisethylspermine: synthesis and growth inhibitory effects on human tumor cell lines.
Journal of medicinal chemistry 1998;41(24):4723-32.
1998: G Aizencang; P Harari; G Buldain; L Guerra; M Pickart; P Hernandez; Benjamin Frydman
Antiproliferative effects of N1,N4-dibenzylputrescine in human and rodent tumor cells.
Cellular and molecular biology (Noisy-le-Grand, France) 1998;44(4):615-25.
1998: M Eileen Dolan; Benjamin Frydman; Craig Thompson; Alan M Diamond; B J Garbiras; A R Safa; William T Beck; Laurence J Marton
Effects of 1,2-naphthoquinones on human tumor cell growth and lack of cross-resistance with other anticancer agents.
Anti-cancer drugs 1998;9(5):437-48.
1998: K Neder; Laurence J Marton; Leroy F Liu; Benjamin Frydman
Reaction of beta-lapachone and related naphthoquinones with 2-mercaptoethanol: a biomimetic model of topoisomerase II poisoning by quinones.
Cellular and molecular biology (Noisy-le-Grand, France) 1998;44(3):465-74.
1997: Benjamin Frydman; Laurence J Marton; J S Sun; K Neder; D T Witiak; Angela A Liu; H M Wang; Yong Mao; H Y Wu; Marilyn M Sanders; Leroy F Liu
Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones.
Cancer research 1997;57(4):620-7.
1995: G Aizencang; R B Frydman; SA Giorgieri; L Sambrotta; L Guerra; Benjamin Frydman
Synthesis of isoornithines and methylputrescines. An evaluation of their inhibitory effects on ornithine decarboxylase.
Journal of medicinal chemistry 1995;38(21):4337-41.
1995: SM Planchon; S Wuerzberger; Benjamin Frydman; D T Witiak; P Hutson; D R Church; George Wilding; David A Boothman
Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.
Cancer research 1995;55(17):3706-11.
1994: C O Fernández; Benjamin Frydman; K Samejima
Interactions between polyamine analogs with antiproliferative effects and tRNA: a 15N NMR analysis.
Cellular and molecular biology (Noisy-le-Grand, France) 1994;40(7):933-44.
1992: S Bari; R B Frydman; CF Grosman; Benjamin Frydman
The interplay between basicity, conformation, and enzymatic reduction in biliverdins.
Biochemical and biophysical research communications 1992;188(1):48-56.
1992: Lucio Frydman; P C Rossomando; V Frydman; C O Fernandez; Benjamin Frydman; K Samejima
Interactions between natural polyamines and tRNA: an 15N NMR analysis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9186-90.
1992: H C Friedmann; M E Duban; A Valasinas; Benjamin Frydman
The enantioselective participation of (S)- and (R)-diaminovaleric acids in the formation of delta-aminolevulinic acid in cyanobacteria.
Biochemical and biophysical research communications 1992;185(1):60-8.
1992: M Fernández; R B Frydman; S Bari; Benjamin Frydman
Reconstitution of apomyoglobin with extended biliverdins.
Biochemical and biophysical research communications 1992;183(3):1209-15.
1990: Benjamin Frydman; C de los Santos; R B Frydman
A 13C NMR study of [5,8-13C2]spermidine binding to tRNA and to Escherichia coli macromolecules.
The Journal of biological chemistry 1990;265(34):20874-8.
1990: Benjamin Frydman; C de los Santos; J J Cannata; Juan J Cazzulo
Carbon-13 nuclear magnetic resonance analysis of [1-13C]glucose metabolism in Trypanosoma cruzi. Evidence of the presence of two alanine pools and of two CO2 fixation reactions.
European journal of biochemistry / FEBS 1990;192(2):363-8.
1990: R B Frydman; S Bari; María L Tomaro; Benjamin Frydman
The enzymatic and chemical reduction of extended biliverdins.
Biochemical and biophysical research communications 1990;171(1):465-73.
1988: S Rosé; R B Frydman; C de los Santos; A Sburlati; A Valasinas; Benjamin Frydman
Spectroscopic evidence for a porphobilinogen deaminase-tetrapyrrole complex that is an intermediate in the biosynthesis of uroporphyrinogen III.
Biochemistry 1988;27(13):4871-9.
1987: R B Frydman; María L Tomaro; J Rosenfeld; Josefina Awruch; L Sambrotta; A Valasinas; Benjamin Frydman
Biliverdin reductase: substrate specificity and kinetics.
Biochimica et biophysica acta 1987;916(3):500-11.
1986: G Buldain; R B Frydman; María L Tomaro; Benjamin Frydman
The chemical and enzymatic oxidation of hematohemin IX. Identification of hematobiliverdin IX alpha as the sole product of the enzymatic oxidation.
European journal of biochemistry / FEBS 1986;156(1):179-84.
1985: C de los Santos; G Buldain; Benjamin Frydman; J J Cannata; Juan J Cazzulo
Carbon-13 nuclear magnetic resonance analysis of [1-13C]glucose metabolism in Crithidia fasciculata. Evidence of CO2 fixation by phosphoenolpyruvate carboxykinase.
European journal of biochemistry / FEBS 1985;149(2):421-9.
1984: María L Tomaro; R B Frydman; Benjamin Frydman; R K Pandey; K M Smith
The oxidation of hemins by microsomal heme oxygenase. Structural requirements for the retention of substrate activity.
Biochimica et biophysica acta 1984;791(3):342-9.
1984: María L Tomaro; R B Frydman; Josefina Awruch; A Valasinas; Benjamin Frydman; R K Pandey; K M Smith
The specificity of biliverdin reductase. A study with different biliverdin types.
Biochimica et biophysica acta 1984;791(3):350-6.
1984: Benjamin Frydman; R B Frydman; C De los Santos; Delia Garrido; S H Goldemberg; Israel D Algranati
Putrescine distribution in Escherichia coli studied in vivo by 13C nuclear magnetic resonance.
Biochimica et biophysica acta 1984;805(4):337-44.
1984: Josefina Awruch; María L Tomaro; R B Frydman; Benjamin Frydman
The specificity of biliverdin reductase. The reduction of biliverdin XIII isomers.
Biochimica et biophysica acta 1984;787(2):146-51.
1984: R B Frydman; María L Tomaro; Josefina Awruch; Benjamin Frydman
Isolation from rat liver of a peroxisomal enzyme which converts molecular form 1 of biliverdin reductase into molecular form 3.
Biochemical and biophysical research communications 1984;121(1):249-54.
1983: R B Frydman; María L Tomaro; Josefina Awruch; Benjamin Frydman
Interconversion of the molecular forms of biliverdin reductase from rat liver.
Biochimica et biophysica acta 1983;759(3):257-63.
1983: A Sburlati; R B Frydman; A Valasinas; S Rosé; H A Priestap; Benjamin Frydman
Biosynthesis of uroporphyrinogens. Interaction among 2-(aminomethyl)bilanes and the enzymatic system.
Biochemistry 1983;22(17):4006-13.
1982: R B Frydman; María L Tomaro; Josefina Awruch; Benjamin Frydman
Molecular forms of biliverdin reductase from rat liver with different reduction rates for biliverdin-IX.
Biochemical and biophysical research communications 1982;105(2):752-8.
1982: Josefina Awruch; Abraham Lemberg; R B Frydman; Benjamin Frydman
Degradation of hemin IX and synthetic hemins to alpha-bilirubins and their conjugates in the isolated perfused rat liver.
Biochimica et biophysica acta 1982;714(2):209-16.
1981: R B Frydman; María L Tomaro; G Buldain; Josefina Awruch; L Díaz; Benjamin Frydman
Specificity of heme oxygenase: a study with synthetic hemins.
Biochemistry 1981;20(18):5177-82.
1979: R B Frydman; Benjamin Frydman
Disappearance of porphobilinogen deaminase activity in leaves before the onset of senescence.
Plant physiology 1979;63(6):1154-7.