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Xiang-Dong Fu

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TOP 3
Zhihong Zhou; Xiang-Dong Fu
Regulation of splicing by SR proteins and SR protein-specific kinases.
Xiong Ji; Hairi Li; Charles Y Lin; Shatakshi Pandit; Rui Xiao; Yu Zhou; Christopher B Burge; Jie Huang; Xiang-Dong Fu
SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase.
Shatakshi Pandit; Jinsong Qiu; Lily Shiue; Gene Yeo; Yu Zhou; Manuel Ares; Gabriela Coutinho-Mansfield; Jie Huang; Hairi Li; Xiang-Dong Fu
Genome-wide Analysis Reveals SR Protein Cooperation and Competition in Regulated Splicing.

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All Publications

2013: Zhihong Zhou; Xiang-Dong Fu
Regulation of splicing by SR proteins and SR protein-specific kinases.
Chromosoma 2013;122(3):191-207.
2013: Xiong Ji; Hairi Li; Charles Y Lin; Shatakshi Pandit; Rui Xiao; Yu Zhou; Christopher B Burge; Jie Huang; Xiang-Dong Fu
SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase.
Cell 2013;153(4):855-68.
2013: Shatakshi Pandit; Jinsong Qiu; Lily Shiue; Gene Yeo; Yu Zhou; Manuel Ares; Gabriela Coutinho-Mansfield; Jie Huang; Hairi Li; Xiang-Dong Fu
Genome-wide Analysis Reveals SR Protein Cooperation and Competition in Regulated Splicing.
Molecular cell 2013;50(2):223-35.
2013: Yuanchao Xue; Kang Zhang; Yi Zhang; Yu Zhou; Yanzhen Bi; Zhiqiang Cai; Ju Chen; Jie Huang; Li Jiang; Hairi Li; Hong Ouyang; Kunfu Ouyang; Hui Sun; Gang Wang; Chaoliang Wei; Qijia Wu; Xiang-Dong Fu
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
Cell 2013;152(1-2):82-96.
2012: Vidisha Tripathi; Xinying Zong; Sergey P Shevtsov; David Y Song; Miroslav Dundr; Xiang-Dong Fu; Stephen Hearn; Kannanganattu V Prasanth
SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles.
Molecular biology of the cell 2012;23(18):3694-706.
2012: Fa-Xing Yu; Haixin Yuan; Bin Zhao; Jiagang Zhao; Jenna L Jewell; Hairi Li; Ian Lian; Gordon B Mills; Nattapon Panupinthu; Karen Tumaneng; Lloyd H Wang; Xiang-Dong Fu; Kun-Liang Guan
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling.
Cell 2012;150(4):780-91.
2012: Zhihong Zhou; Joseph A Adams; Gourisanker Ghosh; Qidong Hu; Hairi Li; Wen Liu; Ryan M Plocinik; Jinsong Qiu; Michael G Rosenfeld; Yu Zhou; Xiang-Dong Fu
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus.
Molecular cell 2012;47(3):422-33.
2012: Hairi Li; Jinsong Qiu; Xiang-Dong Fu
RASL-seq for massively parallel and quantitative analysis of gene expression.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2012;Chapter 4():Unit 4.13.1-9.
2012: Hairi Li; Xiangqiang Li; Jinsong Qiu; Michael G Rosenfeld; Dong Wang; Hongyan Zhou; Yu Zhou; Sheng Ding; Xiang-Dong Fu
Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(12):4609-14.
2012: Rui Xiao; Bo Yang; Yi Zhang; Yu Zhou; Jie Huang; Hairi Li; Changwei Shao; Hui Sun; Peng Tang; Xiang-Dong Fu
Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation.
Molecular cell 2012;45(5):656-68.
2012: Xiong Ji; Xiang-Dong Fu
The mediator couples transcription and splicing.
Molecular cell 2012;45(4):433-4.
2012: Maggie L Chow; Craig April; Cynthia Carter Barnes; Haim Belinson; Jian-Bing Fan; Xiang-Dong Fu; Hai-Ri Li; Sarah Murray; Tiziano Pramparo; Nicholas J Schork; Lauren Weiss; Mary E Winn; Anthony Wynshaw-Boris; Eric Courchesne
Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages.
PLoS genetics 2012;8(3):e1002592.
2012: Maggie L Chow; Eric Courchesne; Jian-Bing Fan; Xiang-Dong Fu; Hai-Ri Li; Mary E Winn; Anthony Wynshaw-Boris; Craig April; Nicholas J Schork
Preprocessing and Quality Control Strategies for Illumina DASL Assay-Based Brain Gene Expression Studies with Semi-Degraded Samples.
Frontiers in genetics 2012;3():11.
2011: Kristi Fox-Walsh; Hairi Li; Yu Zhou; Jeremy Davis-Turak; Xiang-Dong Fu
A multiplex RNA-seq strategy to profile poly(A+) RNA: application to analysis of transcription response and 3' end formation.
Genomics 2011;98(4):266-71.
2011: Ryan M Plocinik; Jennifer Whitehouse; Virgil L Woods; Jennifer Whitesides; Xiang-Dong Fu; Gourisankar Gosh; Kendra L Hailey; Patricia A Jennings; Sheng Li; Tong Liu; Chen-Ting Ma; Joseph A Adams
Regulating SR protein phosphorylation through regions outside the kinase domain of SRPK1.
Journal of molecular biology 2011;410(1):131-45.
2011: Dong Wang; Yiming Zhou; Chris Benner; Ivan Garcia-Bassets; Christopher K Glass; Minna U Kaikkonen; Wenbo Li; Wen Liu; Kenneth A Ohgi; Jinsong Qiu; Michael G Rosenfeld; Xue Su; Xiang-Dong Fu
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA.
Nature 2011;474(7351):390-4.
2011: Joonhee Han; Ji Xiong; Dong Wang; Xiang-Dong Fu
Pre-mRNA splicing: where and when in the nucleus.
Trends in cell biology 2011;21(6):336-43.
2011: Suhyung Cho; Amy Hoang; Rahul Sinha; Xiang-Yang Zhong; Xiang-Dong Fu; Adrian R Krainer; Gourisankar Ghosh
Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(20):8233-8.
2011: Chen Huang; Jingang Huang; Jie Huang; Wei Liu; Qijia Wu; Mao-Hua Xie; Bo Yang; Fan Yang; Xiang-Dong Fu; Yi Zhang
A structured RNA in hepatitis B virus post-transcriptional regulatory element represses alternative splicing in a sequence-independent and position-dependent manner.
The FEBS journal 2011;278(9):1533-46.
2011: Eun-Young Ahn; Russell C DeKelver; Miao-Chia Lo; Tuyet Ann Nguyen; Shinobu Matsuura; Anita Boyapati; Shatakshi Pandit; Xiang-Dong Fu; Dong-Er Zhang
SON controls cell-cycle progression by coordinated regulation of RNA splicing.
Molecular cell 2011;42(2):185-98.
2011: Olivier Harismendy; Dimple Notani; Xiaoyuan Song; Nazli G Rahim; Bogdan Tanasa; Nathaniel Heintzman; Bing Ren; Xiang-Dong Fu; Eric J Topol; Michael G Rosenfeld; Kelly A Frazer
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response.
Nature 2011;470(7333):264-8.
2011: Joonhee Han; Jian-Hua Ding; Cheol W Byeon; Jee H Kim; Klemens J Hertel; Sunjoo Jeong; Xiang-Dong Fu
SR proteins induce alternative exon skipping through their activities on the flanking constitutive exons.
Molecular and cellular biology 2011;31(4):793-802.
2011: Maggie L Chow; Eric Courchesne; Jian-Bing Fan; Xiang-Dong Fu; Hai-Ri Li; Craig April; Cynthia C Barnes; Mary E Winn; Anthony Wynshaw-Boris; Nicholas J Schork
Genome-wide expression assay comparison across frozen and fixed postmortem brain tissue samples.
BMC genomics 2011;12():449.
2011: Michael T Lovci; Hai-Ri Li; Xiang-Dong Fu; Gene Yeo
RNA-seq analysis of gene expression and alternative splicing by double-random priming strategy.
Methods in molecular biology (Clifton, N.J.) 2011;729():247-55.
2010: Chen-Ting Ma; riya ghosh; Xiang-Dong Fu; Joseph A Adams
Mechanism of dephosphorylation of the SR protein ASF/SF2 by protein phosphatase 1.
Journal of molecular biology 2010;403(3):386-404.
2010: Kristi Fox-Walsh; Xiang-Dong Fu
Chromatin: the final frontier in splicing regulation?
Developmental cell 2010;18(3):336-8.
2009: Chunru Lin; Liuqing Yang; Bogdan Tanasa; Kasey R Hutt; Bong-Gun Ju; Kenneth A Ohgi; Jie Zhang; David W Rose; Xiang-Dong Fu; Christopher K Glass; Michael G Rosenfeld
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer.
Cell 2009;139(6):1069-83.
2009: Dong Wang; Xiang-Dong Fu
DNA interaction networks: an information highway for regulated gene expression in the 3-dimentional space of the nucleus.
Cell research 2009;19(12):1316-9.
2009: Esperanza Nunez; Xiang-Dong Fu; Michael G Rosenfeld
Nuclear organization in the 3D space of the nucleus - cause or consequence?
Current opinion in genetics & development 2009;19(5):424-36.
2009: Chen-Ting Ma; Jonathan C Hagopian; riya ghosh; Xiang-Dong Fu; Joseph A Adams
Regiospecific phosphorylation control of the SR protein ASF/SF2 by SRPK1.
Journal of molecular biology 2009;390(4):618-34.
2009: Xiang-Yang Zhong; Pingping Wang; Joonhee Han; Michael G Rosenfeld; Xiang-Dong Fu
SR proteins in vertical integration of gene expression from transcription to RNA processing to translation.
Molecular cell 2009;35(1):1-10.
2009: Xiang-Yang Zhong; Jian-Hua Ding; Joseph A Adams; riya ghosh; Xiang-Dong Fu
Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones.
Genes & development 2009;23(4):482-95.
2008: Jonathan C Hagopian; Chen-Ting Ma; Bryan R Meade; Claudio P Albuquerque; Jacky Chi Ki Ngo; riya ghosh; Patricia Jennings; Xiang-Dong Fu; Joseph A Adams
Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1.
Journal of molecular biology 2008;382(4):894-909.
2008: Shengrong Lin; Gabriela Coutinho-Mansfield; Dong Wang; Shatakshi Pandit; Xiang-Dong Fu
The splicing factor SC35 has an active role in transcriptional elongation.
Nature structural & molecular biology 2008;15(8):819-26.
2008: Esperanza Nunez; Young-Soo Kwon; Kasey R Hutt; Qidong Hu; Maria Dafne Cardamone; Kenneth A Ohgi; Ivan Garcia-Bassets; David W Rose; Christopher K Glass; Michael G Rosenfeld; Xiang-Dong Fu
Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules.
Cell 2008;134(1):189.
2008: Shatakshi Pandit; Dong Wang; Xiang-Dong Fu
Functional integration of transcriptional and RNA processing machineries.
Current opinion in cell biology 2008;20(3):260-5.
2008: Esperanza Nunez; Young-Soo Kwon; Kasey R Hutt; Qidong Hu; Maria Dafne Cardamone; Kenneth A Ohgi; Ivan Garcia-Bassets; David W Rose; Christopher K Glass; Michael G Rosenfeld; Xiang-Dong Fu
Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules.
Cell 2008;132(6):996-1010.
2008: Jacky Chi Ki Ngo; Kayla Giang; Sutapa Chakrabarti; Chen-Ting Ma; Nhat Huynh; Jonathan C Hagopian; Pieter dorrestein; Xiang-Dong Fu; Joseph A Adams; riya ghosh
A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1.
Molecular cell 2008;29(5):563-76.
2008: Chen-Ting Ma; Adolfo Velazquez-Dones; Jonathan C Hagopian; riya ghosh; Xiang-Dong Fu; Joseph A Adams
Ordered multi-site phosphorylation of the splicing factor ASF/SF2 by SRPK1.
Journal of molecular biology 2008;376(1):55-68.
2007: Randall Lukasiewicz; Adolfo Velazquez-Dones; Nhat Huynh; Jonathan C Hagopian; Xiang-Dong Fu; Joseph Adams; riya ghosh
Structurally unique yeast and mammalian serine-arginine protein kinases catalyze evolutionarily conserved phosphorylation reactions.
The Journal of biological chemistry 2007;282(32):23036-43.
2007: Gabriela C Coutinho-Mansfield; Yuanchao Xue; Yi Zhang; Xiang-Dong Fu
PTB/nPTB switch: a post-transcriptional mechanism for programming neuronal differentiation.
Genes & development 2007;21(13):1573-7.
2007: Jianxun Wang; Kathleen Scully; Xiaoyan Zhu; Ling Cai; Jie Zhang; Gratien Prefontaine; Anna Krones; Kenneth A Ohgi; Ping Zhu; Ivan Garcia-Bassets; Forrest Liu; Havilah Taylor; Jean Lozach; Friederike L Jayes; Kenneth S Korach; Christopher K Glass; Xiang-Dong Fu; Michael G Rosenfeld
Opposing LSD1 complexes function in developmental gene activation and repression programmes.
Nature 2007;446(7138):882-7.
2007: Young-Soo Kwon; Ivan Garcia-Bassets; Kasey R Hutt; Christine S Cheng; Mingjie Jin; Dongyan Liu; Chris Benner; Dong Wang; Zhen Ye; Marina Bibikova; Jian-Bing Fan; Lingxun Duan; Christopher K Glass; Michael G Rosenfeld; Xiang-Dong Fu
Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):4852-7.
2007: Ivan Garcia-Bassets; Young-Soo Kwon; Francesca Telese; Gratien Prefontaine; Kasey R Hutt; Christine S Cheng; Bong-Gun Ju; Kenneth A Ohgi; Jianxun Wang; Laure Escoubet-Lozach; David W Rose; Christopher K Glass; Xiang-Dong Fu; Michael G Rosenfeld
Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors.
Cell 2007;128(3):505-18.
2007: Shengrong Lin; Xiang-Dong Fu
SR proteins and related factors in alternative splicing.
Advances in experimental medicine and biology 2007;623():107-22.
2007: Jacky Chi Ki Ngo; Justin Gullingsrud; Kayla Giang; Melinda Jean Yeh; Xiang-Dong Fu; Joseph A Adams; J Andrew McCammon; riya ghosh
SR protein kinase 1 is resilient to inactivation.
Structure (London, England : 1993) 2007;15(1):123-33.
2006: Hai-Ri Li; Jessica Wang-Rodriguez; T Murlidharan Nair; Joanne M Yeakley; Young-Soo Kwon; Marina Bibikova; Christina Zheng; Lixin Zhou; Kui Zhang; Tracy Downs; Xiang-Dong Fu; Jian-Bing Fan
Two-dimensional transcriptome profiling: identification of messenger RNA isoform signatures in prostate cancer from archived paraffin-embedded cancer specimens.
Cancer research 2006;66(8):4079-88.
2006: Jian-Hua Ding; Xiang-Yang Zhong; Jonathan C Hagopian; Marissa M Cruz; riya ghosh; James R Feramisco; Joseph A Adams; Xiang-Dong Fu
Regulated cellular partitioning of SR protein-specific kinases in mammalian cells.
Molecular biology of the cell 2006;17(2):876-85.
2006: Chaolin Zhang; Hai-Ri Li; Jian-Bing Fan; Jessica Wang-Rodriguez; Tracy Downs; Xiang-Dong Fu; Michael Q Zhang
Profiling alternatively spliced mRNA isoforms for prostate cancer classification.
BMC bioinformatics 2006;7():202.
2005: Adolfo Velazquez-Dones; Jonathan C Hagopian; Chen-Ting Ma; Xiang-Yang Zhong; Huilin Zhou; riya ghosh; Xiang-Dong Fu; Joseph A Adams
Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty.
The Journal of biological chemistry 2005;280(50):41761-8.
2005: Xiangdong Xu; Xiang-Dong Fu
Conditional knockout mice to study alternative splicing in vivo.
Methods (San Diego, Calif.) 2005;37(4):387-92.
2005: Christina L Zheng; Xiang-Dong Fu; Michael Gribskov
Characteristics and regulatory elements defining constitutive splicing and different modes of alternative splicing in human and mouse.
RNA (New York, N.Y.) 2005;11(12):1777-87.
2005: Christina L Zheng; Young-Soo Kwon; Hai-Ri Li; Kui Zhang; Gabriela Coutinho-Mansfield; Canzhu Yang; T Murlidharan Nair; Michael Gribskov; Xiang-Dong Fu
MAASE: an alternative splicing database designed for supporting splicing microarray applications.
RNA (New York, N.Y.) 2005;11(12):1767-76.
2005: Shengrong Lin; Ran Xiao; Peiqing Sun; Xiangdong Xu; Xiang-Dong Fu
Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation.
Molecular cell 2005;20(3):413-25.
2005: Jacky Chi Ki Ngo; Sutapa Chakrabarti; Jian-Hua Ding; Adolfo Velazquez-Dones; Bradley Nolen; Brandon E Aubol; Joseph A Adams; Xiang-Dong Fu; riya ghosh
Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.
Molecular cell 2005;20(1):77-89.
2005: Xiangdong Xu; Dongmei Yang; Jian-Hua Ding; Wang Wang; Pao-Hsien Chu; Nancy Dalton; Huan-You Wang; Jamie Pennington; Zhen Ye; Forrest Liu; Michael G Rosenfeld; James L Manley; John Ross; Ju Chen; Rui-Ping Xiao; Heping Cheng; Xiang-Dong Fu
ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle.
Cell 2005;120(1):59-72.
2004: Xiang-Dong Fu
Towards a splicing code.
Cell 2004;119(6):736-8.
2004: Jian-Bing Fan; Joanne M Yeakley; Marina Bibikova; Eugene Chudin; Eliza Wickham; Jing Chen; Dennis Doucet; Philippe Rigault; Baohong Zhang; Richard Shen; celeste mcbride; Hai-Ri Li; Xiang-Dong Fu; Arnold Oliphant; David L Barker; Mark S Chee
A versatile assay for high-throughput gene expression profiling on universal array matrices.
Genome research 2004;14(5):878-85.
2004: Jian-Hua Ding; Xiangdong Xu; Dongmei Yang; Pao-Hsien Chu; Nancy Dalton; Zhen Ye; Joanne M Yeakley; Heping Cheng; Rui-Ping Xiao; John Ross; Ju Chen; Xiang-Dong Fu
Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart.
The EMBO journal 2004;23(4):885-96.
2004: Christina L Zheng; T Murlidharan Nair; Michael Gribskov; Young-Soo Kwon; Hai-Ri Li; Xiang-Dong Fu
A database designed to computationally aid an experimental approach to alternative splicing.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2004;():78-88.
2003: Brandon E Aubol; Sutapa Chakrabarti; Jacky Chi Ki Ngo; Jennifer Shaffer; Bradley Nolen; Xiang-Dong Fu; riya ghosh; Joseph A Adams
Processive phosphorylation of alternative splicing factor/splicing factor 2.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12601-6.
2003: Chi Y Yun; Adolfo Velazquez-Dones; Susan K Lyman; Xiang-Dong Fu
Phosphorylation-dependent and -independent nuclear import of RS domain-containing splicing factors and regulators.
The Journal of biological chemistry 2003;278(20):18050-5.
2002: Joanne M Yeakley; Jian-Bing Fan; Dennis Doucet; Lin Luo; Eliza Wickham; Zhen Ye; Mark S Chee; Xiang-Dong Fu
Profiling alternative splicing on fiber-optic arrays.
Nature biotechnology 2002;20(4):353-8.
2001: S F Dagher; Xiang-Dong Fu
Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4.
RNA (New York, N.Y.) 2001;7(9):1284-97.
2001: Huan-You Wang; Xiangdong Xu; Jian-Hua Ding; Jamie Pennington; Xiang-Dong Fu
SC35 plays a role in T cell development and alternative splicing of CD45.
Molecular cell 2001;7(2):331-42.
2001: Bradley Nolen; Chi Y Yun; C F Wong; J Andrew McCammon; Xiang-Dong Fu; riya ghosh
The structure of Sky1p reveals a novel mechanism for constitutive activity.
Nature structural biology 2001;8(2):176-83.
2000: Chi Y Yun; Xiang-Dong Fu
Conserved SR protein kinase functions in nuclear import and its action is counteracted by arginine methylation in Saccharomyces cerevisiae.
The Journal of cell biology 2000;150(4):707-18.
1999: Joanne M Yeakley; H Tronchère; J Olesen; J A Dyck; H Y Wang; Xiang-Dong Fu
Phosphorylation regulates in vivo interaction and molecular targeting of serine/arginine-rich pre-mRNA splicing factors.
The Journal of cell biology 1999;145(3):447-55.
1999: A Mayeda; Gavin Screaton; S D Chandler; Xiang-Dong Fu; Adrian R Krainer
Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements.
Molecular and cellular biology 1999;19(3):1853-63.
1998: H Y Wang; W Lin; J A Dyck; Joanne M Yeakley; Zhou Songyang; L C Cantley; Xiang-Dong Fu
SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells.
The Journal of cell biology 1998;140(4):737-50.
1997: H Tronchère; J Wang; Xiang-Dong Fu
A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA.
Nature 1997;388(6640):397-400.
1997: S D Chandler; A Mayeda; Joanne M Yeakley; Adrian R Krainer; Xiang-Dong Fu
RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3596-601.
1996: Karen Colwill; L L Feng; J M Yeakley; Gerald Gish; J F Cáceres; Tony Pawson; Xiang-Dong Fu
SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors.
The Journal of biological chemistry 1996;271(40):24569-75.
1996: Joanne M Yeakley; J P Morfin; Michael G Rosenfeld; Xiang-Dong Fu
A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7582-7.
1995: Xiang-Dong Fu
The superfamily of arginine/serine-rich splicing factors.
RNA (New York, N.Y.) 1995;1(7):663-80.
1995: John Bouck; Xiang-Dong Fu; Anna Marie Skalka; Richard Katz
Genetic selection for balanced retroviral splicing: novel regulation involving the second step can be mediated by transitions in the polypyrimidine tract.
Molecular and cellular biology 1995;15(5):2663-71.
1994: J F Gui; H Tronchère; S D Chandler; Xiang-Dong Fu
Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10824-8.
1994: J F Gui; William Stratton Lane; Xiang-Dong Fu
A serine kinase regulates intracellular localization of splicing factors in the cell cycle.
Nature 1994;369(6482):678-82.
1993: Xiang-Dong Fu
Specific commitment of different pre-mRNAs to splicing by single SR proteins.
Nature 1993;365(6441):82-5.
1992: Xiang-Dong Fu; A Mayeda; T Maniatis; Adrian R Krainer
General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11224-8.
1992: Xiang-Dong Fu; T Maniatis
Isolation of a complementary DNA that encodes the mammalian splicing factor SC35.
Science (New York, N.Y.) 1992;256(5056):535-8.
1992: Xiang-Dong Fu; T Maniatis
The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3' splice site.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1725-9.
1991: Xiang-Dong Fu; Richard Katz; Anna Marie Skalka; T Maniatis
The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA.
Genes & development 1991;5(2):211-20.
1990: Xiang-Dong Fu; T Maniatis
Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus.
Nature 1990;343(6257):437-41.
1988: J E Jentoft; L M Smith; Xiang-Dong Fu; Mark T Johnson; Jonathan Leis
Conserved cysteine and histidine residues of the avian myeloblastosis virus nucleocapsid protein are essential for viral replication but are not "zinc-binding fingers".
Proceedings of the National Academy of Sciences of the United States of America 1988;85(19):7094-8.
1988: Xiang-Dong Fu; Richard Katz; Anna Marie Skalka; Jonathan Leis
Site-directed mutagenesis of the avian retrovirus nucleocapsid protein, pp 12. Mutation which affects RNA binding in vitro blocks viral replication.
The Journal of biological chemistry 1988;263(5):2140-5.
1988: Xiang-Dong Fu; P T Tuazon; J A Traugh; Jonathan Leis
Site-directed mutagenesis of the avian retrovirus nucleocapsid protein, pp 12, at Serine 40, the primary site of phosphorylation in vivo.
The Journal of biological chemistry 1988;263(5):2134-9.
1986: Richard Katz; Xiang-Dong Fu; Anna Marie Skalka; Jonathan Leis
Avian retrovirus nucleocapsid protein, pp12, produced in Escherichia coli has biochemical properties identical to unphosphorylated viral protein.
Gene 1986;50(1-3):361-9.