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Elaine Fuchs

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Chiung-Ying Chang; Olivier Elemento; Eugenia G Giannopoulou; Richard M Gronostajski; Geraldine Guasch; H Amalia Pasolli; Elaine Fuchs
NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche.
Slobodan Beronja; Elaine Fuchs
RNAi-mediated gene function analysis in skin.
Elaine Fuchs; Ting Chen
A matter of life and death: self-renewal in stem cells.

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2013: Chiung-Ying Chang; Olivier Elemento; Eugenia G Giannopoulou; Richard M Gronostajski; Geraldine Guasch; H Amalia Pasolli; Elaine Fuchs
NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche.
Nature 2013;495(7439):98-102.
2013: Slobodan Beronja; Elaine Fuchs
RNAi-mediated gene function analysis in skin.
Methods in molecular biology (Clifton, N.J.) 2013;961():351-61.
2013: Elaine Fuchs; Ting Chen
A matter of life and death: self-renewal in stem cells.
EMBO reports 2013;14(1):39-48.
2012: Naoki Oshimori; Elaine Fuchs
The harmonies played by TGF-β in stem cell biology.
Cell stem cell 2012;11(6):751-64.
2012: Mirna Perez-Moreno; Elaine Fuchs
Guilt by association: what p120-catenin has to hide.
The Journal of cell biology 2012;199(2):211-4.
2012: Catherine P Lu; H Amalia Pasolli; Lisa Polak; Ana Sofia Rocha; Neha Sharma; Cédric Blanpain; Shann-Ching Chen; Elaine Fuchs
Identification of stem cell populations in sweat glands and ducts reveals roles in homeostasis and wound repair.
Cell 2012;150(1):136-50.
2012: Elaine Fuchs
Cédric Blanpain: ISSCR's outstanding young investigator for 2012.
Cell stem cell 2012;10(6):751-2.
2012: Elaine Fuchs
The impact of cell culture on stem cell research.
Cell stem cell 2012;10(6):640-1.
2012: Chun-I Wu; Hoang Nguyen; Brian R Shy; Erin M Ford; Elaine Fuchs; Jackson A Hoffman; Bradley J. Merrill
Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interaction.
Development (Cambridge, England) 2012;139(12):2118-29.
2012: Kathleen C Suozzi; Xiaoyang Wu; Elaine Fuchs
Spectraplakins: master orchestrators of cytoskeletal dynamics.
The Journal of cell biology 2012;197(4):465-75.
2012: Ting Chen; Evan Heller; Naoki Oshimori; Nicole Stokes; Slobodan Beronja; Elaine Fuchs
An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration.
Nature 2012;485(7396):104-8.
2012: Geulah Livshits; Agnieszka Kobielak; Elaine Fuchs
Governing epidermal homeostasis by coupling cell-cell adhesion to integrin and growth factor signaling, proliferation, and apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(13):4886-91.
2012: Ya-Chieh Hsu; Elaine Fuchs
A family business: stem cell progeny join the niche to regulate homeostasis.
Nature reviews. Molecular cell biology 2012;13(2):103-14.
2012: Arthur D Lander; Didier Montarras; Andreas Trumpp; Margaret Buckingham; Anne L Calof; Hans Clevers; Elaine Fuchs; Judith Kimble; Thordur Oskarsson
What does the concept of the stem cell niche really mean today?
BMC biology 2012;10():19.
2011: Slobodan Beronja; Elaine Fuchs
A breath of fresh air in lung regeneration.
Cell 2011;147(3):485-7.
2011: Wen-Hui Lien; Lisa Polak; Richard A Young; Deyou Zheng; Xingyi Guo; Lee N Lawton; Elaine Fuchs
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage.
Cell stem cell 2011;9(3):219-32.
2011: Markus Schober; Elaine Fuchs
Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(26):10544-9.
2011: Ellen J Ezratty; Alok S Shah; Nicole Stokes; Scott E Williams; Sophia Chai; Elaine Fuchs
A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.
Cell 2011;145(7):1129-41.
2011: Elaine Fuchs; Valerie Horsley
Ferreting out stem cells from their niches.
Nature cell biology 2011;13(5):513-8.
2011: Liang Zhang; Nicole Stokes; Lisa Polak; Elaine Fuchs
Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment.
Cell stem cell 2011;8(3):294-308.
2011: Chen Luxenburg; H Amalia Pasolli; Scott E Williams; Elaine Fuchs
Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation.
Nature cell biology 2011;13(3):203-14.
2011: Elena Ezhkova; Wen-Hui Lien; Nicole Stokes; Wen-Hui Lien; Jose M Silva; Elaine Fuchs
EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair.
Genes & development 2011;25(5):485-98.
2011: Scott E Williams; Slobodan Beronja; H Amalia Pasolli; Elaine Fuchs
Asymmetric cell divisions promote Notch-dependent epidermal differentiation.
Nature 2011;470(7334):353-8.
2011: Haiying Zhang; H Amalia Pasolli; Elaine Fuchs
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(6):2270-5.
2011: Xiaoyang Wu; Qing-Tao Shen; Daniel S Oristian; Catherine P Lu; Qinsi Zheng; Hong-Wei Wang; Elaine Fuchs
Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3β.
Cell 2011;144(3):341-52.
2011: Ya-Chieh Hsu; H Amalia Pasolli; Elaine Fuchs
Dynamics between stem cells, niche, and progeny in the hair follicle.
Cell 2011;144(1):92-105.
2010: Elena Ezhkova; Elaine Fuchs
Regenerative medicine: An eye to treating blindness.
Nature 2010;466(7306):567-8.
2010: Slobodan Beronja; Geulah Livshits; Scott Williams; Elaine Fuchs
Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos.
Nature medicine 2010;16(7):821-7.
2010: John D Bartlett; Justine Dobeck; Coralee Tye; Mirna Perez-Moreno; Nicole Stokes; Albert B Reynolds; Elaine Fuchs; Ziedonis Skobe
Targeted p120-catenin ablation disrupts dental enamel development.
PloS one 2010;5(9):.
2009: Hoang Nguyen; Bradley J. Merrill; Lisa Polak; Maria Nikolova; Michael Rendl; Timothy M Shaver; H Amalia Pasolli; Elaine Fuchs
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia.
Nature genetics 2009;41(10):1068-75.
2009: Elaine Fuchs
Building confidence: the transition from student to professor.
Nature cell biology 2009;11(7):786.
2009: Elaine Fuchs
Finding one's niche in the skin.
Cell stem cell 2009;4(6):499-502.
2009: Elaine Fuchs
The tortoise and the hair: slow-cycling cells in the stem cell race.
Cell 2009;137(5):811-9.
2009: Elena Ezhkova; H Amalia Pasolli; Joel Parker; Nicole Stokes; I-hsin Su; Gregory Hannon; Alexander Tarakhovsky; Elaine Fuchs
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells.
Cell 2009;136(6):1122-35.
2009: Valentina Greco; Ting Chen; Michael Rendl; Markus Schober; H Amalia Pasolli; Nicole Stokes; June Dela Cruz-Racelis; Elaine Fuchs
A two-step mechanism for stem cell activation during hair regeneration.
Cell stem cell 2009;4(2):155-69.
2009: Rui Yi; H Amalia Pasolli; Markus Landthaler; Markus Hafner; Tolulope Ojo; Robert Sheridan; Chris Sander; Dónal O'Carroll; Markus Stoffel; Thomas Tuschl; Elaine Fuchs
DGCR8-dependent microRNA biogenesis is essential for skin development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):498-502.
2008: Danelle Devenport; Elaine Fuchs
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles.
Nature cell biology 2008;10(11):1257-68.
2008: Christopher L Tinkle; H Amalia Pasolli; Nicole Stokes; Elaine Fuchs
New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15405-10.
2008: Mirna Perez-Moreno; Weimin Song; H Amalia Pasolli; Scott E Williams; Elaine Fuchs
Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15399-404.
2008: Xuan Wang; H Amalia Pasolli; Trevor Williams; Elaine Fuchs
AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis.
The Journal of cell biology 2008;183(1):37-48.
2008: Xiaoyang Wu; Atsuko Kodama; Elaine Fuchs
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity.
Cell 2008;135(1):137-48.
2008: Jonathan A Nowak; Lisa Polak; H Amalia Pasolli; Elaine Fuchs
Hair follicle stem cells are specified and function in early skin morphogenesis.
Cell stem cell 2008;3(1):33-43.
2008: Elaine Fuchs; Valerie Horsley
More than one way to skin . . .
Genes & development 2008;22(8):976-85.
2008: Rui Yi; Matthew N Poy; Markus Stoffel; Elaine Fuchs
A skin microRNA promotes differentiation by repressing 'stemness'.
Nature 2008;452(7184):225-9.
2008: Michael Rendl; Lisa Polak; Elaine Fuchs
BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties.
Genes & development 2008;22(4):543-57.
2008: Elaine Fuchs
Skin stem cells: rising to the surface.
The Journal of cell biology 2008;180(2):273-84.
2008: Valerie Horsley; Antonios O Aliprantis; Lisa Polak; Laurie H Glimcher; Elaine Fuchs
NFATc1 balances quiescence and proliferation of skin stem cells.
Cell 2008;132(2):299-310.
2008: Elaine Fuchs; J A Nowak
Building epithelial tissues from skin stem cells.
Cold Spring Harbor symposia on quantitative biology 2008;73():333-50.
2007: Geraldine Guasch; Markus Schober; H Amalia Pasolli; Emily Belmont Conn; Lisa Polak; Elaine Fuchs
Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia.
Cancer cell 2007;12(4):313-27.
2007: Valerie Horsley; Elaine Fuchs
Reprogramming somatic cells to their embryonic state.
HFSP journal 2007;1(2):89-93.
2007: Krzysztof Kobielak; Nicole Stokes; June de la Cruz; Lisa Polak; Elaine Fuchs
Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(24):10063-8.
2007: Markus Schober; Srikala Raghavan; Maria Nikolova; Lisa Polak; H Amalia Pasolli; Hilary E Beggs; Louis F Reichardt; Elaine Fuchs
Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics.
The Journal of cell biology 2007;176(5):667-80.
2007: Elaine Fuchs
Scratching the surface of skin development.
Nature 2007;445(7130):834-42.
2007: Jinsong Li; Valentina Greco; Geraldine Guasch; Elaine Fuchs; Peter Mombaerts
Mice cloned from skin cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2738-43.
2007: Cédric Blanpain; Valerie Horsley; Elaine Fuchs
Epithelial stem cells: turning over new leaves.
Cell 2007;128(3):445-58.
2007: Terry Lechler; Elaine Fuchs
Desmoplakin: an unexpected regulator of microtubule organization in the epidermis.
The Journal of cell biology 2007;176(2):147-54.
2006: Mirna Perez-Moreno; Elaine Fuchs
Catenins: keeping cells from getting their signals crossed.
Developmental cell 2006;11(5):601-12.
2006: Cédric Blanpain; William Lowry; H Amalia Pasolli; Elaine Fuchs
Canonical notch signaling functions as a commitment switch in the epidermal lineage.
Genes & development 2006;20(21):3022-35.
2006: Hoang Nguyen; Michael Rendl; Elaine Fuchs
Tcf3 governs stem cell features and represses cell fate determination in skin.
Cell 2006;127(1):171-83.
2006: Valerie Horsley; Dónal O'Carroll; Reuben Tooze; Yasuhide Ohinata; Mitinori Saitou; Tetyana Obukhanych; Michel C Nussenzweig; Alexander Tarakhovsky; Elaine Fuchs
Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland.
Cell 2006;126(3):597-609.
2006: Andrea Haegebarth; Wenjun Bie; Ruyan Yang; Susan E Crawford; Valeri Vasioukhin; Elaine Fuchs; Angela L Tyner
Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine.
Molecular and cellular biology 2006;26(13):4949-57.
2006: Horace Rhee; Lisa Polak; Elaine Fuchs
Lhx2 maintains stem cell character in hair follicles.
Science (New York, N.Y.) 2006;312(5782):1946-9.
2006: Rui Yi; Dónal O'Carroll; H Amalia Pasolli; Zhihong Zhang; Fred S Dietrich; Alexander Tarakhovsky; Elaine Fuchs
Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs.
Nature genetics 2006;38(3):356-62.
2006: Agnieszka Kobielak; Elaine Fuchs
Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2322-7.
2006: Mirna Perez-Moreno; Michael A Davis; Ellen Wong; H Amalia Pasolli; Albert B Reynolds; Elaine Fuchs
p120-catenin mediates inflammatory responses in the skin.
Cell 2006;124(3):631-44.
2006: Xuan Wang; Diana Bolotin; David H Chu; Lisa Polak; Trevor Williams; Elaine Fuchs
AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis.
The Journal of cell biology 2006;172(3):409-21.
2006: Cédric Blanpain; Elaine Fuchs
Epidermal stem cells of the skin.
Annual review of cell and developmental biology 2006;22():339-73.
2005: Geraldine Guasch; Elaine Fuchs
Mice in the world of stem cell biology.
Nature genetics 2005;37(11):1201-6.
2005: Michael Rendl; Lisa Lewis; Elaine Fuchs
Molecular dissection of mesenchymal-epithelial interactions in the hair follicle.
PLoS biology 2005;3(11):e331.
2005: Terry Lechler; Elaine Fuchs
Asymmetric cell divisions promote stratification and differentiation of mammalian skin.
Nature 2005;437(7056):275-80.
2005: Laura Alonso; Hitoshi Okada; H Amalia Pasolli; Andrew Wakeham; Annick You-Ten; Tak W Mak; Elaine Fuchs
Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle.
The Journal of cell biology 2005;170(4):559-70.
2005: William Lowry; Cédric Blanpain; Jonathan A Nowak; Geraldine Guasch; Lisa Lewis; Elaine Fuchs
Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells.
Genes & development 2005;19(13):1596-611.
2005: Colin Jamora; Pedro Lee; Pawel Kocieniewski; Mohamad Azhar; Ryoichi Hosokawa; Yang Chai; Elaine Fuchs
A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis.
PLoS biology 2005;3(1):e11.
2004: Atsuko Kodama; Terry Lechler; Elaine Fuchs
Coordinating cytoskeletal tracks to polarize cellular movements.
The Journal of cell biology 2004;167(2):203-7.
2004: Cédric Blanpain; William Lowry; Andrea Geoghegan; Lisa Polak; Elaine Fuchs
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche.
Cell 2004;118(5):635-48.
2004: Agnieszka Kobielak; Elaine Fuchs
Alpha-catenin: at the junction of intercellular adhesion and actin dynamics.
Nature reviews. Molecular cell biology 2004;5(8):614-25.
2004: Elaine Fuchs; Tudorita Tumbar; Geraldine Guasch
Socializing with the neighbors: stem cells and their niche.
Cell 2004;116(6):769-78.
2004: Tudorita Tumbar; Geraldine Guasch; Valentina Greco; Cédric Blanpain; William Lowry; Michael Rendl; Elaine Fuchs
Defining the epithelial stem cell niche in skin.
Science (New York, N.Y.) 2004;303(5656):359-63.
2004: Christopher L Tinkle; Terry Lechler; H Amalia Pasolli; Elaine Fuchs
Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):552-7.
2004: Bradley J. Merrill; H Amalia Pasolli; Lisa Polak; Michael Rendl; Maria J García-García; Kathryn V Anderson; Elaine Fuchs
Tcf3: a transcriptional regulator of axis induction in the early embryo.
Development (Cambridge, England) 2004;131(2):263-74.
2004: Agnieszka Kobielak; H Amalia Pasolli; Elaine Fuchs
Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables.
Nature cell biology 2004;6(1):21-30.
2003: Krzysztof Kobielak; H Amalia Pasolli; Laura Alonso; Lisa Polak; Elaine Fuchs
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA.
The Journal of cell biology 2003;163(3):609-23.
2003: Atsuko Kodama; Iakowos Karakesisoglou; Ellen Wong; Alec Vaezi; Elaine Fuchs
ACF7: an essential integrator of microtubule dynamics.
Cell 2003;115(3):343-54.
2003: Gonçalo Castelo-Branco; Joseph Wagner; Francisco J Rodriguez; Julianna Kele; Kyle M Sousa; Nina Rawal; H Amalia Pasolli; Elaine Fuchs; Jan Kitajewski; Ernest Arenas
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12747-52.
2003: Laura Alonso; Elaine Fuchs
Stem cells of the skin epithelium.
Proceedings of the National Academy of Sciences of the United States of America 2003;100 Suppl 1():11830-5.
2003: Srikala Raghavan; Alec Vaezi; Elaine Fuchs
A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics.
Developmental cell 2003;5(3):415-27.
2003: Charles K Kaufman; Ping Zhou; H Amalia Pasolli; Michael Rendl; Diana Bolotin; Kim-Chew Lim; Xing Dai; Maria-Luisa Alegre; Elaine Fuchs
GATA-3: an unexpected regulator of cell lineage determination in skin.
Genes & development 2003;17(17):2108-22.
2003: Laura Alonso; Elaine Fuchs
Stem cells in the skin: waste not, Wnt not.
Genes & development 2003;17(10):1189-200.
2003: Colin Jamora; Ramanuj DasGupta; Pawel Kocieniewski; Elaine Fuchs
Links between signal transduction, transcription and adhesion in epithelial bud development.
Nature 2003;422(6929):317-22.
2003: Mirna Perez-Moreno; Colin Jamora; Elaine Fuchs
Sticky business: orchestrating cellular signals at adherens junctions.
Cell 2003;112(4):535-48.
2002: Alec Vaezi; Christoph Bauer; Valeri Vasioukhin; Elaine Fuchs
Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium.
Developmental cell 2002;3(3):367-81.
2002: Ramanuj DasGupta; Horace Rhee; Elaine Fuchs
A developmental conundrum: a stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells.
The Journal of cell biology 2002;158(2):331-44.
2002: Charles K Kaufman; Satrajit Sinha; Diana Bolotin; Jie Fan; Elaine Fuchs
Dissection of a complex enhancer element: maintenance of keratinocyte specificity but loss of differentiation specificity.
Molecular and cellular biology 2002;22(12):4293-308.
2002: Baoan Li; Douglas R. Mackay; Qian Dai; Tony W H Li; Mahalakshmi Nair; Magid Fallahi; Christopher P Schonbaum; Judith Fantes; Anthony P Mahowald; Marian L Waterman; Elaine Fuchs; Xing Dai
The LEF1/beta -catenin complex activates movo1, a mouse homolog of Drosophila ovo required for epidermal appendage differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6064-9.
2002: Colin Jamora; Elaine Fuchs
Intercellular adhesion, signalling and the cytoskeleton.
Nature cell biology 2002;4(4):E101-8.
2002: Elaine Fuchs; Srikala Raghavan
Getting under the skin of epidermal morphogenesis.
Nature reviews. Genetics 2002;3(3):199-209.
2002: Sean M Forsythe; Paul Kogut; John McConville; Yiping Fu; Joel A McCauley; Andrew J Halayko; Hong Wei Liu; Allen Kao; Darren J Fernandes; Shashi Bellam; Elaine Fuchs; Satrajit Sinha; Graeme I Bell; Blanca Camoretti-Mercado; Julian Solway
Structure and transcription of the human m3 muscarinic receptor gene.
American journal of respiratory cell and molecular biology 2002;26(3):298-305.
2001: V Vasioukhin; E Bowers; C Bauer; LC Degenstein; Elaine Fuchs
Desmoplakin is essential in epidermal sheet formation.
Nature cell biology 2001;3(12):1076-85.
2001: Elaine Fuchs; Bradley J. Merrill; Colin Jamora; Ramanuj DasGupta
At the roots of a never-ending cycle.
Developmental cell 2001;1(1):13-25.
2001: Bradley J. Merrill; U Gat; Ramanuj DasGupta; Elaine Fuchs
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.
Genes & development 2001;15(13):1688-705.
2001: GI Gallicano; C Bauer; Elaine Fuchs
Rescuing desmoplakin function in extra-embryonic ectoderm reveals the importance of this protein in embryonic heart, neuroepithelium, skin and vasculature.
Development (Cambridge, England) 2001;128(6):929-41.
2001: S Sinha; Elaine Fuchs
Identification and dissection of an enhancer controlling epithelial gene expression in skin.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2455-60.
2001: V Vasioukhin; C Bauer; LC Degenstein; B Wise; Elaine Fuchs
Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin.
Cell 2001;104(4):605-17.
2001: V Vasioukhin; Elaine Fuchs
Actin dynamics and cell-cell adhesion in epithelia.
Current opinion in cell biology 2001;13(1):76-84.
2001: Elaine Fuchs; I Karakesisoglou
Bridging cytoskeletal intersections.
Genes & development 2001;15(1):1-14.
2000: Blanca Camoretti-Mercado; Hong Wei Liu; Andrew J Halayko; Sean M Forsythe; John W Kyle; B Li; Yiping Fu; John McConville; Paul Kogut; Joaquim Vieira; N M Patel; Marc B Hershenson; Elaine Fuchs; Satrajit Sinha; Joseph M Miano; Michael S Parmacek; Janis Burkhardt; Julian Solway
Physiological control of smooth muscle-specific gene expression through regulated nuclear translocation of serum response factor.
The Journal of biological chemistry 2000;275(39):30387-93.
2000: S Raghavan; C Bauer; Gina Mundschau; Q Li; Elaine Fuchs
Conditional ablation of beta1 integrin in skin. Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invagination.
The Journal of cell biology 2000;150(5):1149-60.
2000: C K Kaufman; Elaine Fuchs
It's got you covered. NF-kappaB in the epidermis.
The Journal of cell biology 2000;149(5):999-1004.
2000: I Karakesisoglou; Y Yang; Elaine Fuchs
An epidermal plakin that integrates actin and microtubule networks at cellular junctions.
The Journal of cell biology 2000;149(1):195-208.
2000: Satrajit Sinha; LC Degenstein; C Copenhaver; Elaine Fuchs
Defining the regulatory factors required for epidermal gene expression.
Molecular and cellular biology 2000;20(7):2543-55.
2000: V Vasioukhin; C Bauer; M Yin; Elaine Fuchs
Directed actin polymerization is the driving force for epithelial cell-cell adhesion.
Cell 2000;100(2):209-19.
2000: Elaine Fuchs; JA Segre
Stem cells: a new lease on life.
Cell 2000;100(1):143-55.
1999: Ramanuj DasGupta; Elaine Fuchs
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation.
Development (Cambridge, England) 1999;126(20):4557-68.
1999: Elaine Fuchs; Y Yang
Crossroads on cytoskeletal highways.
Cell 1999;98(5):547-50.
1999: JA Segre; C Bauer; Elaine Fuchs
Klf4 is a transcription factor required for establishing the barrier function of the skin.
Nature genetics 1999;22(4):356-60.
1999: Y Yang; C Bauer; G Strasser; R Wollman; J P Julien; Elaine Fuchs
Integrators of the cytoskeleton that stabilize microtubules.
Cell 1999;98(2):229-38.
1999: V Vasioukhin; LC Degenstein; B Wise; Elaine Fuchs
The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8551-6.
1999: JC Pena; Ameeta Kelekar; Elaine Fuchs; Craig Thompson
Manipulation of outer root sheath cell survival perturbs the hair-growth cycle.
The EMBO journal 1999;18(13):3596-603.
1999: E F Chan; U Gat; J M McNiff; Elaine Fuchs
A common human skin tumour is caused by activating mutations in beta-catenin.
Nature genetics 1999;21(4):410-3.
1998: GI Gallicano; P Kouklis; C Bauer; M Yin; V Vasioukhin; LC Degenstein; Elaine Fuchs
Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage.
The Journal of cell biology 1998;143(7):2009-22.
1998: U Gat; Ramanuj DasGupta; LC Degenstein; Elaine Fuchs
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin.
Cell 1998;95(5):605-14.
1998: Xing Dai; Christopher P Schonbaum; LC Degenstein; W Bai; Anthony P Mahowald; Elaine Fuchs
The ovo gene required for cuticle formation and oogenesis in flies is involved in hair formation and spermatogenesis in mice.
Genes & development 1998;12(21):3452-63.
1998: E Hutton; RD Paladini; QC Yu; M Yen; Pierre A Coulombe; Elaine Fuchs
Functional differences between keratins of stratified and simple epithelia.
The Journal of cell biology 1998;143(2):487-99.
1998: E A Smith; Elaine Fuchs
Defining the interactions between intermediate filaments and desmosomes.
The Journal of cell biology 1998;141(5):1229-41.
1998: Elaine Fuchs; D W Cleveland
A structural scaffolding of intermediate filaments in health and disease.
Science (New York, N.Y.) 1998;279(5350):514-9.
1998: Elaine Fuchs
Beauty is skin deep: the fascinating biology of the epidermis and its appendages.
Harvey lectures 1998;94():47-77.
1997: Elaine Fuchs; James Dowling; JA Segre; Su Hao Lo; QC Yu
Integrators of epidermal growth and differentiation: distinct functions for beta 1 and beta 4 integrins.
Current opinion in genetics & development 1997;7(5):672-82.
1997: James Dowling; Y Yang; Robert Wollmann; Louis F Reichardt; Elaine Fuchs
Developmental expression of BPAG1-n: insights into the spastic ataxia and gross neurologic degeneration in dystonia musculorum mice.
Developmental biology 1997;187(2):131-42.
1997: JC Pena; Elaine Fuchs; Craig Thompson
Bcl-x expression influences keratinocyte cell survival but not terminal differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(6):619-29.
1997: Z Yang; GI Gallicano; QC Yu; Elaine Fuchs
An unexpected localization of basonuclin in the centrosome, mitochondria, and acrosome of developing spermatids.
The Journal of cell biology 1997;137(3):657-69.
1997: Su Hao Lo; QC Yu; LC Degenstein; L B Chen; Elaine Fuchs
Progressive kidney degeneration in mice lacking tensin.
The Journal of cell biology 1997;136(6):1349-61.
1997: Elaine Fuchs
Keith R. Porter Lecture, 1996. Of mice and men: genetic disorders of the cytoskeleton.
Molecular biology of the cell 1997;8(2):189-203.
1997: Xiaodong Wang; Sandra S Zinkel; Kenneth S Polonsky; Elaine Fuchs
Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):219-26.
1997: Elaine Fuchs; Y Yang; James Dowling; P Kouklis; E Smith; L Guo; QC Yu
Intermediate filament linker proteins.
Society of General Physiologists series 1997;52():141-8.
1996: Y Yang; James Dowling; QC Yu; P Kouklis; D W Cleveland; Elaine Fuchs
An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments.
Cell 1996;86(4):655-65.
1996: J Uttam; E Hutton; Pierre A Coulombe; I Anton-Lamprecht; QC Yu; T Gedde-Dahl; Jo-David Fine; Elaine Fuchs
The genetic basis of epidermolysis bullosa simplex with mottled pigmentation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9079-84.
1996: James Dowling; QC Yu; Elaine Fuchs
Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.
The Journal of cell biology 1996;134(2):559-72.
1996: E Allen; QC Yu; Elaine Fuchs
Mice expressing a mutant desmosomal cadherin exhibit abnormalities in desmosomes, proliferation, and epidermal differentiation.
The Journal of cell biology 1996;133(6):1367-82.
1996: Y M Chan; J Cheng; T Gedde-Dahl; K M Niemi; Elaine Fuchs
Genetic analysis of a severe case of Dowling-Meara epidermolysis bullosa simplex.
The Journal of investigative dermatology 1996;106(2):327-34.
1996: L Guo; LC Degenstein; Elaine Fuchs
Keratinocyte growth factor is required for hair development but not for wound healing.
Genes & development 1996;10(2):165-75.
1996: Elaine Fuchs
The cytoskeleton and disease: genetic disorders of intermediate filaments.
Annual review of genetics 1996;30():197-231.
1995: C Lloyd; QC Yu; J Cheng; K Turksen; LC Degenstein; E Hutton; Elaine Fuchs
The basal keratin network of stratified squamous epithelia: defining K15 function in the absence of K14.
The Journal of cell biology 1995;129(5):1329-44.
1995: L Guo; LC Degenstein; James Dowling; QC Yu; R Wollmann; B Perman; Elaine Fuchs
Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration.
Cell 1995;81(2):233-43.
1995: P Zhou; C Byrne; J Jacobs; Elaine Fuchs
Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate.
Genes & development 1995;9(6):700-13.
1995: Anthony Letai; Elaine Fuchs
The importance of intramolecular ion pairing in intermediate filaments.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):92-6.
1995: Elaine Fuchs
Keratins and the skin.
Annual review of cell and developmental biology 1995;11():123-53.
1995: B J Aneskievich; Elaine Fuchs
The A/B domain of truncated retinoic acid receptors can block differentiation and promote features of malignancy.
Journal of cell science 1995;108 ( Pt 1)():195-205.
1994: AS Paller; A J Syder; Y M Chan; QC Yu; E Hutton; G Tadini; Elaine Fuchs
Genetic and clinical mosaicism in a type of epidermal nevus.
The New England journal of medicine 1994;331(21):1408-15.
1994: Elaine Fuchs; Pierre A Coulombe; J Cheng; Y M Chan; E Hutton; A Syder; LC Degenstein; QC Yu; Anthony Letai; Robert Vassar
Genetic bases of epidermolysis bullosa simplex and epidermolytic hyperkeratosis.
The Journal of investigative dermatology 1994;103(5 Suppl):25S-30S.
1994: P D Kouklis; E Hutton; Elaine Fuchs
Making a connection: direct binding between keratin intermediate filaments and desmosomal proteins.
The Journal of cell biology 1994;127(4):1049-60.
1994: Y Chan; I Anton-Lamprecht; QC Yu; A Jäckel; B Zabel; J P Ernst; Elaine Fuchs
A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein.
Genes & development 1994;8(21):2574-87.
1994: Elaine Fuchs; C Byrne
The epidermis: rising to the surface.
Current opinion in genetics & development 1994;4(5):725-36.
1994: Elaine Fuchs; Y M Chan; A S Paller; QC Yu
Cracks in the foundation: keratin filaments and genetic disease.
Trends in cell biology 1994;4(9):321-6.
1994: C Byrne; Michael A Tainsky; Elaine Fuchs
Programming gene expression in developing epidermis.
Development (Cambridge, England) 1994;120(9):2369-83.
1994: I Faus; H J Hsu; Elaine Fuchs
Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia.
Molecular and cellular biology 1994;14(5):3263-75.
1994: Elaine Fuchs
Intermediate filaments and disease: mutations that cripple cell strength.
The Journal of cell biology 1994;125(3):511-6.
1994: Y M Chan; QC Yu; J LeBlanc-Straceski; A Christiano; L Pulkkinen; Raju Kucherlapati; J Uitto; Elaine Fuchs
Mutations in the non-helical linker segment L1-2 of keratin 5 in patients with Weber-Cockayne epidermolysis bullosa simplex.
Journal of cell science 1994;107 ( Pt 4)():765-74.
1994: A J Syder; QC Yu; A S Paller; G Giudice; R Pearson; Elaine Fuchs
Genetic mutations in the K1 and K10 genes of patients with epidermolytic hyperkeratosis. Correlation between location and disease severity.
The Journal of clinical investigation 1994;93(4):1533-42.
1994: Elaine Fuchs; K Weber
Intermediate filaments: structure, dynamics, function, and disease.
Annual review of biochemistry 1994;63():345-82.
1993: M N Teng; K Turksen; C A Jacobs; Elaine Fuchs; Hans Schreiber
Prevention of runting and cachexia by a chimeric TNF receptor-Fc protein.
Clinical immunology and immunopathology 1993;69(2):215-22.
1993: Y M Chan; QC Yu; Jo-David Fine; Elaine Fuchs
The genetic basis of Weber-Cockayne epidermolysis bullosa simplex.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7414-8.
1993: M B McCormick; P Kouklis; A Syder; Elaine Fuchs
The roles of the rod end and the tail in vimentin IF assembly and IF network formation.
The Journal of cell biology 1993;122(2):395-407.
1993: C Byrne; Elaine Fuchs
Probing keratinocyte and differentiation specificity of the human K5 promoter in vitro and in transgenic mice.
Molecular and cellular biology 1993;13(6):3176-90.
1993: Anthony Letai; Pierre A Coulombe; M B McCormick; QC Yu; E Hutton; Elaine Fuchs
Disease severity correlates with position of keratin point mutations in patients with epidermolysis bullosa simplex.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3197-201.
1993: L Guo; QC Yu; Elaine Fuchs
Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice.
The EMBO journal 1993;12(3):973-86.
1993: Elaine Fuchs
Epidermal differentiation and keratin gene expression.
Journal of cell science. Supplement 1993;17():197-208.
1992: Elaine Fuchs
Genetic skin disorders of keratin.
The Journal of investigative dermatology 1992;99(6):671-4.
1992: B J Aneskievich; Elaine Fuchs
Terminal differentiation in keratinocytes involves positive as well as negative regulation by retinoic acid receptors and retinoid X receptors at retinoid response elements.
Molecular and cellular biology 1992;12(11):4862-71.
1992: Robert Vassar; M E Hutton; Elaine Fuchs
Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis.
Molecular and cellular biology 1992;12(10):4643-53.
1992: A K Wilson; Pierre A Coulombe; Elaine Fuchs
The roles of K5 and K14 head, tail, and R/K L L E G E domains in keratin filament assembly in vitro.
The Journal of cell biology 1992;119(2):401-14.
1992: J Cheng; A J Syder; QC Yu; Anthony Letai; A S Paller; Elaine Fuchs
The genetic basis of epidermolytic hyperkeratosis: a disorder of differentiation-specific epidermal keratin genes.
Cell 1992;70(5):811-9.
1992: Elaine Fuchs; R A Esteves; Pierre A Coulombe
Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):6906-10.
1992: J Cheng; K Turksen; QC Yu; Hans Schreiber; M Teng; Elaine Fuchs
Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice.
Genes & development 1992;6(8):1444-56.
1992: Elaine Fuchs; Pierre A Coulombe
Of mice and men: genetic skin diseases of keratin.
Cell 1992;69(6):899-902.
1992: K Turksen; T Kupper; LC Degenstein; Ifor Williams; Elaine Fuchs
Interleukin 6: insights to its function in skin by overexpression in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):5068-72.
1992: Anthony Letai; Pierre A Coulombe; Elaine Fuchs
Do the ends justify the mean? Proline mutations at the ends of the keratin coiled-coil rod segment are more disruptive than internal mutations.
The Journal of cell biology 1992;116(5):1181-95.
1992: K Albers; Elaine Fuchs
The molecular biology of intermediate filament proteins.
International review of cytology 1992;134():243-79.
1991: Pierre A Coulombe; M E Hutton; Robert Vassar; Elaine Fuchs
A function for keratins and a common thread among different types of epidermolysis bullosa simplex diseases.
The Journal of cell biology 1991;115(6):1661-74.
1991: Elaine Fuchs
Keratin genes, epidermal differentiation and animal models for the study of human skin diseases.
Biochemical Society transactions 1991;19(4):1112-5.
1991: Pierre A Coulombe; M E Hutton; Anthony Letai; A Hebert; A S Paller; Elaine Fuchs
Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses.
Cell 1991;66(6):1301-11.
1991: A Leask; C Byrne; Elaine Fuchs
Transcription factor AP2 and its role in epidermal-specific gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(18):7948-52.
1991: K Turksen; Y Choi; Elaine Fuchs
Transforming growth factor alpha induces collagen degradation and cell migration in differentiating human epidermal raft cultures.
Cell regulation 1991;2(8):613-25.
1991: V Stellmach; A Leask; Elaine Fuchs
Retinoid-mediated transcriptional regulation of keratin genes in human epidermal and squamous cell carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4582-6.
1991: M B McCormick; Pierre A Coulombe; Elaine Fuchs
Sorting out IF networks: consequences of domain swapping on IF recognition and assembly.
The Journal of cell biology 1991;113(5):1111-24.
1991: Robert Vassar; Elaine Fuchs
Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.
Genes & development 1991;5(5):714-27.
1991: Robert Vassar; Pierre A Coulombe; LC Degenstein; K Albers; Elaine Fuchs
Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease.
Cell 1991;64(2):365-80.
1991: M Rosenberg; Elaine Fuchs; Michelle M Le Beau; R L Eddy; TB Shows
Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12.
Cytogenetics and cell genetics 1991;57(1):33-8.
1990: Elaine Fuchs
Epidermal differentiation: the bare essentials.
The Journal of cell biology 1990;111(6 Pt 2):2807-14.
1990: Pierre A Coulombe; Y M Chan; K Albers; Elaine Fuchs
Deletions in epidermal keratins leading to alterations in filament organization in vivo and in intermediate filament assembly in vitro.
The Journal of cell biology 1990;111(6 Pt 2):3049-64.
1990: A Leask; M Rosenberg; Robert Vassar; Elaine Fuchs
Regulation of a human epidermal keratin gene: sequences and nuclear factors involved in keratinocyte-specific transcription.
Genes & development 1990;4(11):1985-98.
1990: Y Choi; Elaine Fuchs
TGF-beta and retinoic acid: regulators of growth and modifiers of differentiation in human epidermal cells.
Cell regulation 1990;1(11):791-809.
1990: Pierre A Coulombe; Elaine Fuchs
Elucidating the early stages of keratin filament assembly.
The Journal of cell biology 1990;111(1):153-69.
1989: V M Stellmach; Elaine Fuchs
Exploring the mechanisms underlying cell type-specific and retinoid-mediated expression of keratins.
The New biologist 1989;1(3):305-17.
1989: A Stoler; M Duvic; Elaine Fuchs
Unusual patterns of keratin expression in the overlying epidermis of patients with dermatofibromas: biochemical alterations in the epidermis as a consequence of dermal tumors.
The Journal of investigative dermatology 1989;93(6):728-38.
1989: Pierre A Coulombe; R Kopan; Elaine Fuchs
Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation.
The Journal of cell biology 1989;109(5):2295-312.
1989: R Lersch; V Stellmach; C Stocks; G Giudice; Elaine Fuchs
Isolation, sequence, and expression of a human keratin K5 gene: transcriptional regulation of keratins and insights into pairwise control.
Molecular and cellular biology 1989;9(9):3685-97.
1989: R Kopan; Elaine Fuchs
The use of retinoic acid to probe the relation between hyperproliferation-associated keratins and cell proliferation in normal and malignant epidermal cells.
The Journal of cell biology 1989;109(1):295-307.
1989: K Albers; Elaine Fuchs
Expression of mutant keratin cDNAs in epithelial cells reveals possible mechanisms for initiation and assembly of intermediate filaments.
The Journal of cell biology 1989;108(4):1477-93.
1989: Robert Vassar; M Rosenberg; S Ross; Angela L Tyner; Elaine Fuchs
Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(5):1563-7.
1989: R Kopan; Elaine Fuchs
A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin.
Genes & development 1989;3(1):1-15.
1988: D J McCance; R Kopan; Elaine Fuchs; Laimonis A Laimins
Human papillomavirus type 16 alters human epithelial cell differentiation in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(19):7169-73.
1988: C Glass; Elaine Fuchs
Isolation, sequence, and differential expression of a human K7 gene in simple epithelial cells.
The Journal of cell biology 1988;107(4):1337-50.
1988: A Stoler; R Kopan; M Duvic; Elaine Fuchs
Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.
The Journal of cell biology 1988;107(2):427-46.
1988: M Rosenberg; A RayChaudhury; TB Shows; Michelle M Le Beau; Elaine Fuchs
A group of type I keratin genes on human chromosome 17: characterization and expression.
Molecular and cellular biology 1988;8(2):722-36.
1988: R Lersch; Elaine Fuchs
Sequence and expression of a type II keratin, K5, in human epidermal cells.
Molecular and cellular biology 1988;8(1):486-93.
1987: K H Kim; V Stellmach; J Javors; Elaine Fuchs
Regulation of human mesothelial cell differentiation: opposing roles of retinoids and epidermal growth factor in the expression of intermediate filament proteins.
The Journal of cell biology 1987;105(6 Pt 2):3039-51.
1987: Elaine Fuchs; Angela L Tyner; G J Giudice; D Marchuk; A RayChaudhury; M Rosenberg
The human keratin genes and their differential expression.
Current topics in developmental biology 1987;22():5-34.
1986: A RayChaudhury; D Marchuk; M Lindhurst; Elaine Fuchs
Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes.
Molecular and cellular biology 1986;6(2):539-48.
1985: Elaine Fuchs; Israel Hanukoglu; D Marchuk; M P Grace; K H Kim
The nature and significance of differential keratin gene expression.
Annals of the New York Academy of Sciences 1985;455():436-50.
1983: Elaine Fuchs; Israel Hanukoglu
Unraveling the structure of the intermediate filaments.
Cell 1983;34(2):332-4.
1983: Israel Hanukoglu; Elaine Fuchs
The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins.
Cell 1983;33(3):915-24.
1983: Israel Hanukoglu; Naoko Tanese; Elaine Fuchs
Complementary DNA sequence of a human cytoplasmic actin. Interspecies divergence of 3' non-coding regions.
Journal of molecular biology 1983;163(4):673-8.
1983: Elaine Fuchs; K H Kim; Israel Hanukoglu; Naoko Tanese
The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.
Current problems in dermatology 1983;11():27-44.
1982: Israel Hanukoglu; Elaine Fuchs
The cDNA sequence of a human epidermal keratin: divergence of sequence but conservation of structure among intermediate filament proteins.
Cell 1982;31(1):243-52.