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Lars Fugger

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Lars Fugger; Gil McVean; John I Bell
Genomewide association studies and common disease--realizing clinical utility.
Adam P Gregory; Aiden Haghikia; Gurman Kaur; Lydia Lambert; Oliver A Leach; Matthias Mann; Gil McVean; Finn C Nielsen; Gereon Poschmann; Simone Prömel; Divya Punwani; Richard M Siegel; Dionysia K Xifara; Kathrine E Attfield; John I Bell; Falk Butter; Simon J Davis; Calliope A Dendrou; James H Felce; Ralf Gold; Lars Fugger
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.
J Antonio González; Lise T Jensen; Lars Fugger; Denis Burdakov
Convergent inputs from electrically and topographically distinct orexin cells to locus coeruleus and ventral tegmental area.

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All Publications

2012: Lars Fugger; Gil McVean; John I Bell
Genomewide association studies and common disease--realizing clinical utility.
The New England journal of medicine 2012;367(25):2370-1.
2012: Adam P Gregory; Aiden Haghikia; Gurman Kaur; Lydia Lambert; Oliver A Leach; Matthias Mann; Gil McVean; Finn C Nielsen; Gereon Poschmann; Simone Prömel; Divya Punwani; Richard M Siegel; Dionysia K Xifara; Kathrine E Attfield; John I Bell; Falk Butter; Simon J Davis; Calliope A Dendrou; James H Felce; Ralf Gold; Lars Fugger
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.
Nature 2012;488(7412):508-11.
2012: J Antonio González; Lise T Jensen; Lars Fugger; Denis Burdakov
Convergent inputs from electrically and topographically distinct orexin cells to locus coeruleus and ventral tegmental area.
The European journal of neuroscience 2012;35(9):1426-32.
2012: Andrew E Armitage; Chih-Hao Chang; Koen Deforche; Lars Fugger; Jan Gerstoft; Beatrice Kramer; Andrew McMichael; Andrew Rambaut; Edmund Wee; John J Welch; Astrid K N Iversen
APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete "all or nothing" phenomenon.
PLoS genetics 2012;8(3):e1002550.
2011: Anne Venner; Lars Fugger; J Antonio Gonzalez; Lise T Jensen; Mahesh M Karnani; Denis Burdakov
Orexin neurons as conditional glucosensors: paradoxical regulation of sugar sensing by intracellular fuels.
The Journal of physiology 2011;589(Pt 23):5701-8.
2011: Mahesh M Karnani; Antoine Adamantidis; John Apergis-Schoute; Luis de Lecea; Lars Fugger; Lise T Jensen; Denis Burdakov
Activation of central orexin/hypocretin neurons by dietary amino acids.
Neuron 2011;72(4):616-29.
2011: Róisín M McMahon; Lone Friis; Christian Siebold; Manuel A Friese; Lars Fugger; E Yvonne Jones
Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis.
Acta crystallographica. Section D, Biological crystallography 2011;67(Pt 5):447-54.
2011: John S Tzartos; Matthew J Craner; Manuel A Friese; Karen B Jakobsen; Jia Newcombe; Margaret M Esiri; Lars Fugger
IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain.
The American journal of pathology 2011;178(2):794-802.
2011: Sandra Vergo; Matthew J Craner; Ruth Etzensperger; Kathrine Attfield; Manuel A Friese; Jia Newcombe; Margaret Esiri; Lars Fugger
Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.
Brain : a journal of neurology 2011;134(Pt 2):571-84.
2011: Mahesh M Karnani; Anne Venner; Lise T Jensen; Lars Fugger; Denis Burdakov
Direct and indirect control of orexin/hypocretin neurons by glycine receptors.
The Journal of physiology 2011;589(Pt 3):639-51.
2010: Konstantina Nika; Cristiana Soldani; Mogjiborahman Salek; Wolfgang Paster; Adrian Gray; Ruth Etzensperger; Lars Fugger; Paolo Polzella; Vincenzo Cerundolo; Omer Dushek; Thomas Höfer; Antonella Viola; Oreste Acuto
Constitutively active Lck kinase in T cells drives antigen receptor signal transduction.
Immunity 2010;32(6):766-77.
2009: J A González; Lise T Jensen; Susan E Doyle; Manuel Miranda-Anaya; Michael Menaker; Lars Fugger; Douglas A Bayliss; Denis Burdakov
Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons.
The European journal of neuroscience 2009;30(1):57-64.
2009: Lars Fugger; Manuel A Friese; John I Bell
From genes to function: the next challenge to understanding multiple sclerosis.
Nature reviews. Immunology 2009;9(6):408-17.
2009: Stefan Tenzer; Edmund Wee; Anne Burgevin; Guillaume Stewart-Jones; Lone Friis; Kasper Lamberth; Chih-hao Chang; Mikkel Harndahl; Mirjana Weimershaus; Jan Gerstoft; Nadja Akkad; Paul Klenerman; Lars Fugger; E Yvonne Jones; Andrew J McMichael; Søren Buus; Hansjörg Schild; Peter van Endert; Astrid K N Iversen
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance.
Nature immunology 2009;10(6):636-46.
2009: Maria Harkiolaki; Samantha L Holmes; Pia Svendsen; Jon W Gregersen; Lise T Jensen; Roisin McMahon; Manuel A Friese; Gijs van Boxel; Ruth Etzensperger; John S Tzartos; Kamil Kranc; Sarah Sainsbury; Karl Harlos; Elizabeth D Mellins; Jackie Palace; Margaret M Esiri; Philip van der Merwe; E Yvonne Jones; Lars Fugger
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides.
Immunity 2009;30(3):348-57.
2009: J Antonio González; emilia horjales; Lars Fugger; Christian Broberger; Denis Burdakov
Stimulation of orexin/hypocretin neurones by thyrotropin-releasing hormone.
The Journal of physiology 2009;587(Pt 6):1179-86.
2008: Manuel A Friese; Karen B Jakobsen; Lone Friis; Ruth Etzensperger; Matthew J Craner; Róisín M McMahon; Lise T Jensen; Véronique Huygelen; E Yvonne Jones; John I Bell; Lars Fugger
Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.
Nature medicine 2008;14(11):1227-35.
2008: Ruth Etzensperger; Róisín M McMahon; E Yvonne Jones; Lars Fugger
Dissection of the multiple sclerosis associated DR2 haplotype.
Journal of autoimmunity 2008;31(3):201-7.
2008: J Antonio González; Lise T Jensen; Lars Fugger; Denis Burdakov
Metabolism-independent sugar sensing in central orexin neurons.
Diabetes 2008;57(10):2569-76.
2008: Rhiannan H Williams; Haris Alexopoulos; Lise T Jensen; Lars Fugger; Denis Burdakov
Adaptive sugar sensors in hypothalamic feeding circuits.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11975-80.
2008: Ioana Moisini; Phuong Nguyen; Lars Fugger; Terrence L Geiger
Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-zeta chimeric receptor.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3601-11.
2008: John S Tzartos; Manuel A Friese; Matthew J Craner; Jackie Palace; Jia Newcombe; Margaret M Esiri; Lars Fugger
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis.
The American journal of pathology 2008;172(1):146-55.
2007: Manuel A Friese; Matthew J Craner; Ruth Etzensperger; Sandra Vergo; John A Wemmie; Michael J Welsh; Angela Vincent; Lars Fugger
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.
Nature medicine 2007;13(12):1483-9.
2007: Manuel A Friese; Lars Fugger
T cells and microglia as drivers of multiple sclerosis pathology.
Brain : a journal of neurology 2007;130(Pt 11):2755-7.
2007: Rhîannan H Williams; Lise T Jensen; Alexei Verkhratsky; Lars Fugger; Denis Burdakov
Control of hypothalamic orexin neurons by acid and CO2.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10685-90.
2006: Manuel A Friese; Lise T Jensen; Nick Willcox; Lars Fugger
Humanized mouse models for organ-specific autoimmune diseases.
Current opinion in immunology 2006;18(6):704-9.
2006: Jon W Gregersen; Kamil R Kranc; Xiayi Ke; Pia Svendsen; Lars S Madsen; Allan Randrup Thomsen; Lon R Cardon; John I Bell; Lars Fugger
Functional epistasis on a common MHC haplotype associated with multiple sclerosis.
Nature 2006;443(7111):574-7.
2006: Manuel A Friese; Xavier Montalban; Nick Willcox; John I Bell; Roland Martin; Lars Fugger
The value of animal models for drug development in multiple sclerosis.
Brain : a journal of neurology 2006;129(Pt 8):1940-52.
2006: Denis Burdakov; Lise T Jensen; Haris Alexopoulos; Rhiannan H Williams; Ian M Fearon; Ita O'Kelly; Oleg Gerasimenko; Lars Fugger; Alexei Verkhratsky
Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose.
Neuron 2006;50(5):711-22.
2006: E Yvonne Jones; Lars Fugger; Jack L Strominger; Christian Siebold
MHC class II proteins and disease: a structural perspective.
Nature reviews. Immunology 2006;6(4):271-82.
2006: Balik Dzhambazov; Kutty Selva Nandakumar; Jan Kihlberg; Lars Fugger; Rikard Holmdahl; Mikael Vestberg
Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1525-33.
2006: Astrid K N Iversen; Guillaume Stewart-Jones; Gerald Learn; Natasha Christie; Christina Sylvester-Hviid; Andrew E Armitage; Rupert Kaul; Tara Beattie; Jean K Lee; Yanping Li; Pojchong Chotiyarnwong; Tao Dong; Xiaoning Xu; Mark A Luscher; Kelly MacDonald; Henrik Ullum; Bente Klarlund Pedersen; Peter Skinhøj; Lars Fugger; Soren Buus; James I Mullins; E Yvonne Jones; Philip van der Merwe; Andrew J McMichael
Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope.
Nature immunology 2006;7(2):179-89.
2005: Manuel A Friese; E Yvonne Jones; Lars Fugger
MHC II molecules in inflammatory diseases: interplay of qualities and quantities.
Trends in immunology 2005;26(11):559-61.
2005: Manuel A Friese; Lars Fugger
Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?
Brain : a journal of neurology 2005;128(Pt 8):1747-63.
2005: Samantha Holmes; Manuel A Friese; Christian Siebold; E Yvonne Jones; John Bell; Lars Fugger
Multiple sclerosis: MHC associations and therapeutic implications.
Expert reviews in molecular medicine 2005;7(3):1-17.
2005: Kamil R Kranc; Andrew M Taylor; Nick Willcox; Lars Fugger
Control of autoimmunity by "epitope theft".
Trends in molecular medicine 2005;11(1):1-4.
2004: Pia Svendsen; Claus B Andersen; Nick Willcox; Anthony J Coyle; Rikard Holmdahl; Thomas Kamradt; Lars Fugger
Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):7037-45.
2004: Astrid K N Iversen; Jørn Attermann; Jan Gerstoft; Lars Fugger; James I Mullins; Peter Skinhøj
Longitudinal and cross-sectional studies of HIV-1 RNA and DNA loads in blood and the female genital tract.
European journal of obstetrics, gynecology, and reproductive biology 2004;117(2):227-35.
2004: J W Gregersen; S Holmes; Lars Fugger
Humanized animal models for autoimmune diseases.
Tissue antigens 2004;63(5):383-94.
2004: Christian Siebold; Bjarke E Hansen; Jessica R Wyer; Karl Harlos; Robert E Esnouf; Arne Svejgaard; John I Bell; Jack L Strominger; E Yvonne Jones; Lars Fugger
Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):1999-2004.
2003: Kristian Stengaard-Pedersen; Steffen Thiel; Mihaela Gadjeva; Mette Møller-Kristensen; Rikke Sørensen; Lise T Jensen; Anders G Sjøholm; Lars Fugger; Jens C Jensenius
Inherited deficiency of mannan-binding lectin-associated serine protease 2.
The New England journal of medicine 2003;349(6):554-60.
2003: Simon J Davis; Shinji Ikemizu; Edward J Evans; Lars Fugger; Talitha Bakker; Philip van der Merwe
The nature of molecular recognition by T cells.
Nature immunology 2003;4(3):217-24.
2003: Astrid K N Iversen; Claus Bohn Christiansen; Jørn Attermann; Jesper Eugen-Olsen; Sam Schulman; Erik Berntorp; Jørgen Ingerslev; Lars Fugger; Elma Scheibel; Lilian Tengborn; Jan Gerstoft; Ebbe Dickmeiss; Arne Svejgaard; Peter Skinhøj
Limited protective effect of the CCR5Delta32/CCR5Delta32 genotype on human immunodeficiency virus infection incidence in a cohort of patients with hemophilia and selection for genotypic X4 virus.
The Journal of infectious diseases 2003;187(2):215-25.
2002: Heather L E Lang; Helle Jacobsen; Shinji Ikemizu; Christina Andersson; Karl Harlos; Lars Madsen; Peter Hjorth; Leif Sondergaard; Arne Svejgaard; Kai W Wucherpfennig; David I Stuart; John I Bell; E Yvonne Jones; Lars Fugger
A functional and structural basis for TCR cross-reactivity in multiple sclerosis.
Nature immunology 2002;3(10):940-3.
2002: Johan Bäcklund; Stefan Carlsen; Torsten Höger; Björn Holm; Lars Fugger; Jan Kihlberg; Harald Burkhardt; Rikard Holmdahl
Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):9960-5.
2002: Masha Fridkis-Hareli; Laura Santambrogio; Joel N H Stern; Lars Fugger; Celia F Brosnan; Jack L Strominger
Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis.
The Journal of clinical investigation 2002;109(12):1635-43.
2001: Masha Fridkis-Hareli; Joel N H Stern; Lars Fugger; Jack L Strominger
Synthetic peptides that inhibit binding of the myelin basic protein 85-99 epitope to multiple sclerosis-associated HLA-DR2 molecules and MBP-specific T-cell responses.
Human immunology 2001;62(8):753-63.
2000: Lars Fugger
Human autoimmunity genes in mice.
Current opinion in immunology 2000;12(6):698-703.
2000: Masha Fridkis-Hareli; E F Rosloniec; Lars Fugger; Jack L Strominger
Synthetic peptides that inhibit binding of the collagen type II 261-273 epitope to rheumatoid arthritis-associated HLA-DR1 and -DR4 molecules and collagen-specific T-cell responses.
Human immunology 2000;61(7):640-50.
2000: Michelle Krogsgaard; Kai W Wucherpfennig; Barbara Cannella; B E Hansen; Arne Svejgaard; Jason Pyrdol; H Ditzel; Cedric S Raine; Jan Engberg; Lars Fugger; B Canella
Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex.
The Journal of experimental medicine 2000;191(8):1395-412.
2000: Bert Maier; M Molinger; Andrew P Cope; Lars Fugger; J Schneider-Mergener; Grete Sønderstrup; Thomas Kamradt; A Kramer
Multiple cross-reactive self-ligands for Borrelia burgdorferi-specific HLA-DR4-restricted T cells.
European journal of immunology 2000;30(2):448-57.
2000: E C Andersson; Pia Svendsen; A Svejgaard; R Holmdahl; Lars Fugger
A molecule basis for the HLA association in rheumatoid arthritis.
Reviews in immunogenetics 2000;2(1):81-7.
2000: Lars Fugger; A Svejgaard
Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men.
Arthritis research 2000;2(3):208-11.
2000: Lars Fugger
Joint-specific and systemic autoreactivity in the development of inflammatory arthritis.
Arthritis research 2000;2(1):2-4.
1999: Astrid K N Iversen; Gerald Learn; Lars Fugger; Jan Gerstoft; James I Mullins; P Skinhoj
Presence of multiple HIV subtypes and a high frequency of subtype chimeric viruses in heterosexually infected women.
Journal of acquired immune deficiency syndromes (1999) 1999;22(4):325-32.
1999: Grete Sønderstrup; Andrew P Cope; Salil Patel; Mauro Congia; N Hain; Frances C Hall; Sarah Louise Parry; Lars Fugger; Sara A Michie; Hugh McDevitt
HLA class II transgenic mice: models of the human CD4+ T-cell immune response.
Immunological reviews 1999;172():335-43.
1999: Lars S Madsen; EC Andersson; L Jansson; Michelle Krogsgaard; C B Andersen; Jan Engberg; Jack L Strominger; Arne Svejgaard; J P Hjorth; R Holmdahl; Kai W Wucherpfennig; Lars Fugger
A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor.
Nature genetics 1999;23(3):343-7.
1999: L Norgaard; Lars Fugger; Hans O Madsen; Arne Svejgaard
Identification of 4 different alternatively spliced HLA-A transcripts.
Tissue antigens 1999;54(4):370-8.
1999: L Madsen; N Labrecque; Jan Engberg; A Dierich; Arne Svejgaard; Christophe Benoist; Diane Mathis; Lars Fugger
Mice lacking all conventional MHC class II genes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(18):10338-43.
1999: Hanne Quarsten; Oyvind Molberg; Lars Fugger; Stephen N McAdam; Ludvig M Sollid
HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope.
European journal of immunology 1999;29(8):2506-14.
1999: Rikard Holmdahl; E C Andersson; C B Andersen; A Svejgaard; Lars Fugger
Transgenic mouse models of rheumatoid arthritis.
Immunological reviews 1999;169():161-73.
1999: Jan Engberg; Michelle Krogsgaard; Lars Fugger
Recombinant antibodies with the antigen-specific, MHC restricted specificity of T cells: novel reagents for basic and clinical investigations and immunotherapy.
Immunotechnology : an international journal of immunological engineering 1999;4(3-4):273-8.
1998: Astrid K N Iversen; Lars Fugger; Jesper Eugen-Olsen; Ulla Balslev; T Jensen; S Wahl; Jan Gerstoft; James I Mullins; P Skinhoj
Cervical human immunodeficiency virus type 1 shedding is associated with genital beta-chemokine secretion.
The Journal of infectious diseases 1998;178(5):1334-42.
1998: Masha Fridkis-Hareli; E F Rosloniec; Lars Fugger; Jack L Strominger
Synthetic amino acid copolymers that bind to HLA-DR proteins and inhibit type II collagen-reactive T cell clones.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12528-31.
1998: EC Andersson; BE Hansen; H Jacobsen; Lars S Madsen; C B Andersen; Jan Engberg; J B Rothbard; G S McDevitt; V Malmström; R Holmdahl; Arne Svejgaard; Lars Fugger
Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7574-9.
1998: Oyvind Molberg; Stephen N McAdam; R Körner; Hanne Quarsten; C Kristiansen; L Madsen; Lars Fugger; Helge Scott; Ove Norén; Peter Roepstorff; Knut E A Lundin; Hans Sjöström; Ludvig M Sollid
Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease.
Nature medicine 1998;4(6):713-7.
1998: Astrid K N Iversen; Anders Rhod Larsen; T Jensen; Lars Fugger; Ulla Balslev; S Wahl; Jan Gerstoft; James I Mullins; Peter Skinhøj
Distinct determinants of human immunodeficiency virus type 1 RNA and DNA loads in vaginal and cervical secretions.
The Journal of infectious diseases 1998;177(5):1214-20.
1998: Peter Kjellén; U Brunsberg; J Broddefalk; B Hansen; Mikael Vestberg; I Ivarsson; A Engström; A Svejgaard; Jan Kihlberg; Lars Fugger; Rikard Holmdahl
The structural basis of MHC control of collagen-induced arthritis; binding of the immunodominant type II collagen 256-270 glycopeptide to H-2Aq and H-2Ap molecules.
European journal of immunology 1998;28(2):755-67.
1998: BE Hansen; EC Andersson; Lars S Madsen; Jan Engberg; Lars Søndergaard; Arne Svejgaard; Lars Fugger
Functional characterization of HLA-DRA1*0101/DRB1*0401 molecules expressed in Drosophila melanogaster cells.
Tissue antigens 1998;51(2):119-28.
1997: Lars Fugger; Arne Svejgaard
The HLA-DQ7 and -DQ8 associations in DR4-positive rheumatoid arthritis patients. A combined analysis of data available in the literature.
Tissue antigens 1997;50(5):494-500.
1997: SD Patel; Andrew P Cope; Mauro Congia; T T Chen; E Kim; Lars Fugger; D Wherrett; G Sonderstrup-McDevitt
Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):8082-7.
1997: L Norgaard; Lars Fugger; B K Jakobsen; Arne Svejgaard
Sequencing-based typing of HLA-A locus using mRNA and a single locus-specific PCR followed by cycle-sequencing with AmpliTaq DNA polymerase, FS.
Tissue antigens 1997;49(5):455-65.
1997: Niels Odum; Lars Fugger; Ebbe Dickmeiss
Arne Svejgaard and immunogenetics in Denmark.
Tissue antigens 1997;49(3 Pt 1):291-2.
1996: M Röpke; J Hald; Per Guldberg; Jesper Zeuthen; L Nørgaard; Lars Fugger; Arne Svejgaard; Sjoerd H van der burg; H W Nijman; C J Melief; Mogens H Claesson
Spontaneous human squamous cell carcinomas are killed by a human cytotoxic T lymphocyte clone recognizing a wild-type p53-derived peptide.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14704-7.
1996: A Stryhn; P S Andersen; LO Pedersen; Arne Svejgaard; A Holm; Christopher Thorpe; Lars Fugger; Soren Buus; Jan Engberg
Shared fine specificity between T-cell receptors and an antibody recognizing a peptide/major histocompatibility class I complex.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10338-42.
1996: Lars Fugger; J B Rothbard; G Sonderstrup-McDevitt
Specificity of an HLA-DRB1*0401-restricted T cell response to type II collagen.
European journal of immunology 1996;26(4):928-33.
1996: P S Andersen; A Stryhn; B E Hansen; Lars Fugger; Jan Engberg; Soren Buus
A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(5):1820-4.
1996: Lars Fugger; J Liang; A Gautam; J B Rothbard; Hugh McDevitt
Quantitative analysis of peptides from myelin basic protein binding to the MHC class II protein, I-Au, which confers susceptibility to experimental allergic encephalomyelitis.
Molecular medicine (Cambridge, Mass.) 1996;2(2):181-8.
1994: Lars Fugger; Sara A Michie; I Rulifson; C B Lock; G S McDevitt
Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):6151-5.
1994: P M van Endert; Roland S Liblau; SD Patel; Lars Fugger; T Lopez; Flemming Pociot; J Nerup; Hugh McDevitt
Major histocompatibility complex-encoded antigen processing gene polymorphism in IDDM.
Diabetes 1994;43(1):110-7.
1993: Roland Tisch; XD Yang; S M Singer; Roland S Liblau; Lars Fugger; Hugh McDevitt
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.
Nature 1993;366(6450):72-5.
1993: Roland S Liblau; P M van Endert; M Sandberg-Wollheim; SD Patel; M T Lopez; S Land; Lars Fugger; Hugh McDevitt
Antigen processing gene polymorphisms in HLA-DR2 multiple sclerosis.
Neurology 1993;43(6):1192-7.
1992: Hans O Madsen; L P Ryder; Lars Fugger; N Odum; B K Jakobsen; A Svejgaard
New DPB1 alleles.
Tissue antigens 1992;39(2):102-3.
1992: Niels Morling; K Dalhoff; Lars Fugger; J Georgsen; B Jakobsen; L Ranek; Niels Odum; Arne Svejgaard
DNA polymorphism of HLA class II genes in primary biliary cirrhosis.
Immunogenetics 1992;35(2):112-6.
1992: Niels Morling; M Sandberg-Wollheim; Lars Fugger; J Georgsen; J J Hylding-Nielsen; Hans O Madsen; Klaus Rieneck; L Ryder; Arne Svejgaard
Immunogenetics of multiple sclerosis and optic neuritis: DNA polymorphism of HLA class II genes.
Immunogenetics 1992;35(6):391-4.
1991: Niels Morling; Vagn Andersen; Lars Fugger; J Georgsen; P Halberg; P Oxholm; Niels Odum; Arne Svejgaard
Immunogenetics of rheumatoid arthritis and primary Sjögren's syndrome: DNA polymorphism of HLA class II genes.
Disease markers 1991;9(5):289-96.
1991: Niels Morling; J Friis; Lars Fugger; J Georgsen; Carsten Heilmann; Freddy Karup Pedersen; Niels Odum; Arne Svejgaard
DNA polymorphism of HLA class II genes in pauciarticular juvenile rheumatoid arthritis.
Tissue antigens 1991;38(1):16-23.
1991: Niels Morling; G Frentz; Lars Fugger; J Georgsen; B Jakobsen; Niels Odum; Arne Svejgaard
DNA polymorphism of HLA class II genes in alopecia areata.
Disease markers 1991;9(1):35-42.
1991: Lars Fugger; Niels Morling; L P Ryder; B K Jakobsen; Vagn Andersen; P Oxholm; K Dalhoff; Carsten Heilmann; F Karup Pedersen; J Friis
Restriction fragment length polymorphism of two HLA-B-associated transcripts genes in five autoimmune diseases.
Human immunology 1991;30(1):27-31.
1990: Lars Fugger; N Morling; L P Ryder; B K Jakobsen; A Svejgaard; T Spies; Jack L Strominger
Restriction fragment length polymorphism (RFLP) of two HLA-B-associated transcripts (BATs) genes in healthy Danes.
Tissue antigens 1990;36(2):57-61.
1990: Lars Fugger; Niels Morling; L P Ryder; Niels Odum; Arne Svejgaard
Technical aspects of typing for HLA-DP alleles using allele-specific DNA in vitro amplification and sequence-specific oligonucleotide probes. Detection of single base mismatches.
Journal of immunological methods 1990;129(2):175-85.
1990: Niels Odum; J Georgsen; Lars Fugger; J Møller; B K Jakobsen; B Hofmann; P Skinhøj; M Klokker; Ebbe Dickmeiss; Arne Svejgaard
HLA-DP antigens in HIV-infected individuals.
Disease markers 1990;8(3):113-6.
1990: Lars Fugger; Niels Morling; M Sandberg-Wollheim; L P Ryder; Arne Svejgaard
Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis.
Journal of neuroimmunology 1990;27(1):85-8.
1990: Niels Odum; Niels Morling; J Georgsen; B K Jakobsen; G Frentz; G F Jensen; Lars Fugger; Arne Svejgaard
HLA-DP antigens in patients with alopecia areata.
Tissue antigens 1990;35(3):114-7.
1990: Lars Fugger; L P Ryder; Niels Morling; Niels Odum; J Friis; Freddy Karup Pedersen; Carsten Heilmann; M Sandberg-Wollheim; Arne Svejgaard
DNA typing for HLA-DPB1*02 and -DPB1*04 in multiple sclerosis and juvenile rheumatoid arthritis.
Immunogenetics 1990;32(3):150-6.
1990: Lars Fugger; M Sandberg-Wollheim; Niels Morling; L P Ryder; Arne Svejgaard
The germline repertoire of T-cell receptor beta chain genes in patients with relapsing/remitting multiple sclerosis or optic neuritis.
Immunogenetics 1990;31(4):278-80.
1989: Lars Fugger; Niels Morling; K Bendtzen; L Ryder; Vagn Andersen; C Heilman; F Karup Pedersen; J Friis; P Halbert; Arne Svejgaard
IL-6 gene polymorphism in rheumatoid arthritis, pauciarticular juvenile rheumatoid arthritis, systemic lupus erythematosus, and in healthy Danes.
Journal of immunogenetics 1989;16(6):461-5.
1989: Lars Fugger; Niels Morling; K Bendtzen; L P Ryder; Arne Svejgaard
BglII polymorphism in the human interleukin 6 (IL 6) gene.
Nucleic acids research 1989;17(18):7548.
1989: Lars Fugger; K Bendtzen; N Morling; L Ryder; A Svejgaard
Possible correlation of TNF alpha-production with -RFLP in humans.
European journal of haematology 1989;43(3):255-6.
1989: Lars Fugger; Niels Morling; L P Ryder; P Platz; J Georgsen; B K Jakobsen; Arne Svejgaard; K Dalhoff; L Ranek
NcoI restriction fragment length polymorphism (RFLP) of the tumour necrosis factor (TNF alpha) region in primary biliary cirrhosis and in healthy Danes.
Scandinavian journal of immunology 1989;30(2):185-9.
1989: Lars Fugger; Niels Morling; L P Ryder; J Georgsen; B K Jakobsen; Arne Svejgaard; Vagn Andersen; P Oxholm; F Karup Pedersen; J Friis
NcoI restriction fragment length polymorphism (RFLP) of the tumor necrosis factor (TNF alpha) region in four autoimmune diseases.
Tissue antigens 1989;34(1):17-22.
1989: Lars Fugger; Niels Morling; K Bendtzen; L Ryder; Niels Odum; J Georgsen; Arne Svejgaard
MspI polymorphism in the human interleukin 6 (IL 6) gene.
Nucleic acids research 1989;17(11):4419.
1989: Lars Fugger; Niels Morling; L P Ryder; Niels Odum; J Georgsen; Arne Svejgaard
Typing for HLA-DPB1*03 and HLA-DPB1*06 using allele-specific DNA in vitro amplification and allele-specific oligonucleotide probes. Detection of "new" DPB1*06 variants.
Immunogenetics 1989;30(3):208-13.
1987: Lars Fugger; P Platz; L Ryder; A Svejgaard; J Heldrup; Henrik Hertz; M Yssing
Immunological reclassification of 22 children with a former diagnosis of non-T, non-B ALL.
European journal of haematology 1987;39(4):369-75.