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Hiroaki Fujihara

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Toru Ishikura; Akiko Katoh; Makoto Kawasaki; Toshitaka Nakamura; Toyoaki Ohbuchi; Jun-ichi Ohkubo; Hideo Ohnishi; Motoko Ohno; Hitoshi Suzuki; Hiroaki Fujihara; Mitsuhiro Yoshimura; Yoichi Ueta
Expression of the c-fos-monomeric red fluorescent protein 1 fusion gene in the spinal cord and the hypothalamic paraventricular nucleus in transgenic rats after nociceptive stimulation.
Motoko Ohno; Miwako Todoroki; Hiroaki Fujihara; Kenji Hachisuka; Akinori Hamamura; Toru Ishikura; Masaru Iwanaga; Akiko Katoh; Toyoaki Ohbuchi; Yoichi Ueta
Induction of arginine vasopressin-enhanced green fluorescent protein expression in the locus coeruleus following kainic acid-induced seizures in rats.
Masaru Iwanaga; Akiko Katoh; Masayoshi Nomura; Toyoaki Ohbuchi; Motoko Ohno; Hiroaki Fujihara; Kenji Hachisuka; Toru Ishikura; Yoichi Ueta
Upregulation of arginine vasopressin synthesis in the rat hypothalamus after kainic acid-induced seizures.

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All Publications

2012: Toru Ishikura; Akiko Katoh; Makoto Kawasaki; Toshitaka Nakamura; Toyoaki Ohbuchi; Jun-ichi Ohkubo; Hideo Ohnishi; Motoko Ohno; Hitoshi Suzuki; Hiroaki Fujihara; Mitsuhiro Yoshimura; Yoichi Ueta
Expression of the c-fos-monomeric red fluorescent protein 1 fusion gene in the spinal cord and the hypothalamic paraventricular nucleus in transgenic rats after nociceptive stimulation.
Brain research 2012;1479():52-61.
2012: Motoko Ohno; Miwako Todoroki; Hiroaki Fujihara; Kenji Hachisuka; Akinori Hamamura; Toru Ishikura; Masaru Iwanaga; Akiko Katoh; Toyoaki Ohbuchi; Yoichi Ueta
Induction of arginine vasopressin-enhanced green fluorescent protein expression in the locus coeruleus following kainic acid-induced seizures in rats.
Stress (Amsterdam, Netherlands) 2012;15(4):435-42.
2011: Masaru Iwanaga; Akiko Katoh; Masayoshi Nomura; Toyoaki Ohbuchi; Motoko Ohno; Hiroaki Fujihara; Kenji Hachisuka; Toru Ishikura; Yoichi Ueta
Upregulation of arginine vasopressin synthesis in the rat hypothalamus after kainic acid-induced seizures.
Brain research 2011;1424():1-8.
2011: Akiko Katoh; Mitsuhiro Kawata; Toyoaki Ohbuchi; Tatsushi Onaka; Hideaki Suzuki; Hiroaki Fujihara; Takashi Hashimoto; Yoichi Ueta
Highly visible expression of an oxytocin-monomeric red fluorescent protein 1 fusion gene in the hypothalamus and posterior pituitary of transgenic rats.
Endocrinology 2011;152(7):2768-74.
2011: Toyoaki Ohbuchi; Toru Yokoyama; Takeshi Saito; Jun-Ichi Ohkubo; Hideaki Suzuki; Toru Ishikura; Akiko Katoh; Hiroaki Fujihara; Hirofumi Hashimoto; Hideaki Suzuki; Yoichi Ueta
Possible contribution of pannexin channel to ATP-induced currents in vitro in vasopressin neurons isolated from the rat supraoptic nucleus.
Brain research 2011;1394():71-8.
2011: Hitoshi Suzuki; Hirofumi Hashimoto; Makoto Kawasaki; Miho Watanabe; Hiroki Otsubo; Toru Ishikura; Hiroaki Fujihara; Hideo Ohnishi; Etsuro Onuma; Hisafumi Yamada-Okabe; Yoh Takuwa; Etsuro Ogata; Toshitaka Nakamura; Yoichi Ueta
Similar changes of hypothalamic feeding-regulating peptides mRNAs and plasma leptin levels in PTHrP-, LIF-secreting tumors-induced cachectic rats and adjuvant arthritic rats.
International journal of cancer. Journal international du cancer 2011;128(9):2215-23.
2011: Toru Yokoyama; Toyoaki Ohbuchi; Takeshi Saito; Yuka Sudo; Hiroaki Fujihara; Kouichiro Minami; Toshihisa Nagatomo; Yasuhito Uezono; Yoichi Ueta
Allyl isothiocyanates and cinnamaldehyde potentiate miniature excitatory postsynaptic inputs in the supraoptic nucleus in rats.
European journal of pharmacology 2011;655(1-3):31-7.
2011: Yoichi Ueta; Govindin Dayanithi; Hiroaki Fujihara
Hypothalamic vasopressin response to stress and various physiological stimuli: visualization in transgenic animal models.
Hormones and behavior 2011;59(2):221-6.
2010: Takashi Maruyama; Toyoaki Ohbuchi; Hiroaki Fujihara; Minori Shibata; Koji Mori; David Murphy; Govindan Dayanithi; Yoichi Ueta
Diurnal changes of arginine vasopressin-enhanced green fluorescent protein fusion transgene expression in the rat suprachiasmatic nucleus.
Peptides 2010;31(11):2089-93.
2010: Toyoaki Ohbuchi; Toru Yokoyama; Takeshi Saito; Hideaki Suzuki; Hiroaki Fujihara; Akiko Katoh; Hiroki Otsubo; Toru Ishikura; Hideaki Suzuki; Yoichi Ueta
Modulators of BK and SK channels alter electrical activity in vitro in single vasopressin neurons isolated from the rat supraoptic nucleus.
Neuroscience letters 2010;484(1):26-9.
2010: Miwako Todoroki; Yoichi Ueta; Hiroaki Fujihara; Hiroki Otsubo; Minori Shibata; Hirofumi Hashimoto; Mizuki Kobayashi; Hirotaka Sakamoto; Mitsuhiro Kawata; Govindan Dayanithi; David Murphy; Hisanori Hiro; Ken Takahashi; Shoji Nagata
Induction of the arginine vasopressin-enhanced green fluorescent protein fusion transgene in the rat locus coeruleus.
Stress (Amsterdam, Netherlands) 2010;13(4):281-91.
2010: Hiroki Otsubo; Tatsushi Onaka; Hitoshi Suzuki; Akiko Katoh; Toyoaki Ohbuchi; Miwako Todoroki; Mizuki Kobayashi; Hiroaki Fujihara; Toru Yokoyama; Tetsuro Matsumoto; Yoichi Ueta
Centrally administered relaxin-3 induces Fos expression in the osmosensitive areas in rat brain and facilitates water intake.
Peptides 2010;31(6):1124-30.
2010: Toyoaki Ohbuchi; T Yokoyama; Hiroaki Fujihara; Hideaki Suzuki; Yoichi Ueta
Electrophysiological identification of the functional presynaptic nerve terminals on an isolated single vasopressin neurone of the rat supraoptic nucleus.
Journal of neuroendocrinology 2010;22(5):413-9.
2010: Akiko Katoh; Hiroaki Fujihara; Toyoaki Ohbuchi; Tatsushi Onaka; W Scott Young; Govindan Dayanithi; Yuka Yamasaki; Mitsuhiro Kawata; Hitoshi Suzuki; Hiroki Otsubo; Hideaki Suzuki; David Murphy; Yoichi Ueta
Specific expression of an oxytocin-enhanced cyan fluorescent protein fusion transgene in the rat hypothalamus and posterior pituitary.
The Journal of endocrinology 2010;204(3):275-85.
2010: Toru Yokoyama; Takeshi Saito; Toyoaki Ohbuchi; Hirofumi Hashimoto; Hitoshi Suzuki; Hiroki Otsubo; Hiroaki Fujihara; Toshihisa Nagatomo; Yoichi Ueta
TRPV1 gene deficiency attenuates miniature EPSC potentiation induced by mannitol and angiotensin II in supraoptic magnocellular neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(3):876-84.
2010: Hirofumi Hashimoto; Hiroki Otsubo; Hiroaki Fujihara; Hitoshi Suzuki; Toyoaki Ohbuchi; Toru Yokoyama; Yoshio Takei; Yoichi Ueta
Centrally administered ghrelin potently inhibits water intake induced by angiotensin II and hypovolemia in rats.
The journal of physiological sciences : JPS 2010;60(1):19-25.
2009: Hiroaki Fujihara; Yoichi Ueta; Hitoshi Suzuki; Akiko Katoh; Toyoaki Ohbuchi; Hiroki Otsubo; Govindan Dayanithi; David Murphy
Robust up-regulation of nuclear red fluorescent-tagged fos marks neuronal activation in green fluorescent vasopressin neurons after osmotic stimulation in a double-transgenic rat.
Endocrinology 2009;150(12):5633-8.
2009: Mizuki Kobayashi; Masayoshi Nomura; Hiroaki Fujihara; Hitoshi Suzuki; Hiroki Otsubo; Hisae Nishii; Naohiro Fujimoto; Tetsuro Matsumoto; Yoichi Ueta
Involvement of orexin-A on micturition reflex in normal and cyclophosphamide-induced cystitis bladder in rat.
Peptides 2009;30(12):2348-56.
2009: T Yokoyama; Takeshi Saito; Toyoaki Ohbuchi; Hideaki Suzuki; Hiroki Otsubo; T Okamoto; Hiroaki Fujihara; T Nagatomo; Yoichi Ueta
Ghrelin potentiates miniature excitatory postsynaptic currents in supraoptic magnocellular neurones.
Journal of neuroendocrinology 2009;21(11):910-20.
2009: Hiroki Otsubo; Susumu Hyodo; Hirofumi Hashimoto; Makoto Kawasaki; Hitoshi Suzuki; Takeshi Saito; Toyoaki Ohbuchi; Toru Yokoyama; Hiroaki Fujihara; Tetsuro Matsumoto; Yoshio Takei; Yoichi Ueta
Centrally administered adrenomedullin 5 activates oxytocin-secreting neurons in the hypothalamus and elevates plasma oxytocin level in rats.
The Journal of endocrinology 2009;202(2):237-47.
2009: Toyoaki Ohbuchi; Toru Yokoyama; Takeshi Saito; Hirofumi Hashimoto; Hideaki Suzuki; Hiroki Otsubo; Hiroaki Fujihara; Hideaki Suzuki; Yoichi Ueta
Brain-derived neurotrophic factor inhibits spontaneous inhibitory postsynaptic currents in the rat supraoptic nucleus.
Brain research 2009;1258():34-42.
2009: Hideaki Suzuki; Tatsushi Onaka; M Kasai; Makoto Kawasaki; Hideo Ohnishi; Hiroki Otsubo; Takeshi Saito; Hiroshi Hashimoto; T Yokoyama; Hiroaki Fujihara; Govindan Dayanithi; D Murphy; Tetsuya Nakamura; Yoichi Ueta
Response of arginine vasopressin-enhanced green fluorescent protein fusion gene in the hypothalamus of adjuvant-induced arthritic rats.
Journal of neuroendocrinology 2009;21(3):183-90.
2008: Yoichi Ueta; Hiroaki Fujihara; Govindan Dayanithi; M Kawata; D Murphy
Specific expression of optically active reporter gene in arginine vasopressin-secreting neurosecretory cells in the hypothalamic-neurohypophyseal system.
Journal of neuroendocrinology 2008;20(6):660-4.
2008: Hirofumi Hashimoto; Kazuo Kitamura; Makoto Kawasaki; Takeshi Saito; Hitoshi Suzuki; Hiroki Otsubo; Toyoaki Ohbuchi; Toru Yokoyama; Hiroaki Fujihara; Yoshio Takei; Yoichi Ueta
Adrenomedullin 2/intermedin-like immunoreactivity in the hypothalamus and brainstem of rats.
Autonomic neuroscience : basic & clinical 2008;139(1-2):46-54.
2008: Takeshi Saito; Govindan Dayanithi; Jun Saito; Tatsushi Onaka; T Urabe; T X Watanabe; Hiroshi Hashimoto; T Yokoyama; Hiroaki Fujihara; A Yokota; S Nishizawa; Y Hirata; Yoichi Ueta
Chronic osmotic stimuli increase salusin-beta-like immunoreactivity in the rat hypothalamo-neurohypophyseal system: possible involvement of salusin-beta on [Ca2+]i increase and neurohypophyseal hormone release from the axon terminals.
Journal of neuroendocrinology 2008;20(2):207-19.
2007: Masamichi Kuwajima; Hiroaki Fujihara; Hiroyoshi Sei; Asako Umehara; Masako Sei; Tomi T Tsuda; Akiko Sukeno; Tatsuya Okamoto; Akiko Inubushi; Yoichi Ueta; Toshio Doi; Hiroshi Kido
Reduced carnitine level causes death from hypoglycemia: possible involvement of suppression of hypothalamic orexin expression during weaning period.
Endocrine journal 2007;54(6):911-25.
2007: Takashi Mera; Hiroaki Fujihara; Jun Saito; Makoto Kawasaki; Hirofumi Hashimoto; Takeshi Saito; Minori Shibata; Tatsushi Onaka; Yoshiya Tanaka; Takakazu Oka; Sadatoshi Tsuji; Yoichi Ueta
Downregulation of prolactin-releasing peptide gene expression in the hypothalamus and brainstem of diabetic rats.
Peptides 2007;28(8):1596-604.
2007: Makoto Kawasaki; Jun Saito; Hirofumi Hashimoto; Hitoshi Suzuki; Hiroki Otsubo; Hiroaki Fujihara; Hideo Ohnishi; Toshitaka Nakamura; Yoichi Ueta
Induction of the galanin-like peptide gene expression in the posterior pituitary gland after acute osmotic stimulus in rats.
Neuroscience letters 2007;419(2):125-30.
2007: Hirofumi Hashimoto; Susumu Hyodo; Makoto Kawasaki; Minori Shibata; Takeshi Saito; Hitoshi Suzuki; Hiroki Otsubo; Toru Yokoyama; Hiroaki Fujihara; Takashi Higuchi; Yoshio Takei; Yoichi Ueta
Adrenomedullin 2 (AM2)/intermedin is a more potent activator of hypothalamic oxytocin-secreting neurons than AM possibly through an unidentified receptor in rats.
Peptides 2007;28(5):1104-12.
2007: M Shibata; Hiroaki Fujihara; H Suzuki; H Ozawa; M Kawata; Govindan Dayanithi; D Murphy; Yoichi Ueta
Physiological studies of stress responses in the hypothalamus of vasopressin-enhanced green fluorescent protein transgenic rat.
Journal of neuroendocrinology 2007;19(4):285-92.
2007: Hirofumi Hashimoto; Hiroaki Fujihara; Makoto Kawasaki; Takeshi Saito; Minori Shibata; Hiroki Otsubo; Yoshio Takei; Yoichi Ueta
Centrally and peripherally administered ghrelin potently inhibits water intake in rats.
Endocrinology 2007;148(4):1638-47.
2007: Ken Okabayashi; Etsuo Kasahara; Hiroko Uchiyama; Kazuhiko Yokota; Yuki Togashi; Chiyoko Kono; Yoshihito Yamada; Hiroko Amano; Tetsuo Yamaguchi; Toshihiro Kawamoto; Hiroaki Fujihara; Yoichi Ueta
Obstructive sleep apnea-hypopnea syndrome patients with overweight and hypertension in a Japanese workplace.
Journal of occupational health 2007;49(2):117-24.
2007: Hirofumi Hashimoto; Yumiko Azuma; Makoto Kawasaki; Hiroaki Fujihara; Etsuro Onuma; Hisafumi Yamada-Okabe; Yoh Takuwa; Etsuro Ogata; Yoichi Ueta
Parathyroid hormone-related protein induces cachectic syndromes without directly modulating the expression of hypothalamic feeding-regulating peptides.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):292-8.
2007: Makoto Kawasaki; Tatsushi Onaka; Jun Saito; Hiroshi Hashimoto; H Suzuki; H Otsubo; Hiroaki Fujihara; Nobukazu Okimoto; Hideo Ohnishi; Tetsuya Nakamura; Yoichi Ueta
Effects of the short chain sugar acid 2-buten-4-olide on the hypothalamo-pituitary-adrenal axis in normal and adjuvant-induced arthritic rats.
Journal of neuroendocrinology 2007;19(1):54-65.
2006: T Fujio; Hiroaki Fujihara; M Shibata; S Yamada; Tatsushi Onaka; K Tanaka; H Morita; Govindan Dayanithi; M Kawata; D Murphy; Y Ueta
Exaggerated response of arginine vasopressin-enhanced green fluorescent protein fusion gene to salt loading without disturbance of body fluid homeostasis in rats.
Journal of neuroendocrinology 2006;18(10):776-85.
2006: Takashi Mera; Hiroaki Fujihara; Makoto Kawasaki; Hiroshi Hashimoto; Takeshi Saito; Minori Shibata; Jun Saito; Takakazu Oka; Sadatoshi Tsuji; Tatsushi Onaka; Yoichi Ueta
Prolactin-releasing peptide is a potent mediator of stress responses in the brain through the hypothalamic paraventricular nucleus.
Neuroscience 2006;141(2):1069-86.
2006: Makoto Kawasaki; Tatsushi Onaka; Masamitsu Nakazato; Jun Saito; Takashi Mera; Hirofumi Hashimoto; Hiroaki Fujihara; Nobukazu Okimoto; Hideo Ohnishi; Toshitaka Nakamura; Yoichi Ueta
Centrally administered neuropeptide W-30 activates magnocellular neurosecretory cells in the supraoptic and paraventricular nuclei with neurosecretion in rats.
The Journal of endocrinology 2006;190(2):213-23.
2006: Makoto Kawasaki; Chiyo Yamaga; Tatsushi Onaka; Jun Saito; Takashi Mera; Hirofumi Hashimoto; Hiroaki Fujihara; Nobukazu Okimoto; Hideo Ohnishi; Toshitaka Nakamura; Yoichi Ueta
The short chain sugar acid, 2-buten-4-olide, activates oxytocin-secreting neurons but not arginine vasopressin-secreting neurons in the hypothalamus of rats.
Brain research 2006;1086(1):133-41.
2005: Hirofumi Hashimoto; Susumu Hyodo; Makoto Kawasaki; Takashi Mera; Lei Chen; Atsushi Soya; Takeshi Saito; Hiroaki Fujihara; Takashi Higuchi; Yoshio Takei; Yoichi Ueta
Centrally administered adrenomedullin 2 activates hypothalamic oxytocin-secreting neurons, causing elevated plasma oxytocin level in rats.
American journal of physiology. Endocrinology and metabolism 2005;289(5):E753-61.
2005: Atsushi Soya; Ryota Serino; Hiroaki Fujihara; Tatsushi Onaka; Yumi Ozaki; Takeshi Saito; Jun Nakamura; Yoichi Ueta
Cannabinoids modulate synaptic activity in the rat supraoptic nucleus.
Journal of neuroendocrinology 2005;17(9):609-15.
2005: Hirofumi Hashimoto; Tatsushi Onaka; Makoto Kawasaki; Lei Chen; Takashi Mera; Atsushi Soya; Takeshi Saito; Hiroaki Fujihara; Hiroyoshi Sei; Yusuke Morita; Yoichi Ueta
Effects of cholecystokinin (CCK)-8 on hypothalamic oxytocin-secreting neurons in rats lacking CCK-A receptor.
Autonomic neuroscience : basic & clinical 2005;121(1-2):16-25.
2005: Makoto Kawasaki; KI Yamaguchi; Jun Saito; Yumi Ozaki; Takashi Mera; Hiroshi Hashimoto; Hiroaki Fujihara; Nobukazu Okimoto; Hideo Ohnishi; Tetsuya Nakamura; Yoichi Ueta
Expression of immediate early genes and vasopressin heteronuclear RNA in the paraventricular and supraoptic nuclei of rats after acute osmotic stimulus.
Journal of neuroendocrinology 2005;17(4):227-37.
2005: Hiroaki Fujihara; Yoichi Ueta
[Effects of renin-angiotensin system in the central nervous system].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 3():107-10.
2005: Yoichi Ueta; Hiroaki Fujihara; Ryota Serino; Govindan Dayanithi; Hitoshi Ozawa; Ken-ichi Matsuda; Mitsuhiro Kawata; Junko Yamada; Shinya Ueno; Atsuo Fukuda; David Murphy
Transgenic expression of enhanced green fluorescent protein enables direct visualization for physiological studies of vasopressin neurons and isolated nerve terminals of the rat.
Endocrinology 2005;146(1):406-13.
2004: Reiko Hanada; Hitoshi Teranishi; James Todd Pearson; Mamoru Kurokawa; Hiroshi Hosoda; Nobuhiro Fukushima; Yoshihiko Fukue; Ryota Serino; Hiroaki Fujihara; Yoichi Ueta; Masahito Ikawa; Masaru Okabe; Noboru Murakami; Mikiyasu Shirai; Hironobu Yoshimatsu; Kenji Kangawa; Masayasu Kojima
Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway.
Nature medicine 2004;10(10):1067-73.
2004: Makoto Yokota; Yumi Ozaki; Fumihiko Sakamoto; Seiji Yamada; Jun Saito; Hiroaki Fujihara; Yoichi Ueta
Fos expression in CRF-containing neurons in the rat paraventricular nucleus after central administration of neuromedin U.
Stress (Amsterdam, Netherlands) 2004;7(2):109-12.
2003: Hiroaki Fujihara; Ryota Serino; Yoichi Ueta; Hiroyoshi Sei; Yusuke Morita
Six-hour selective REM sleep deprivation increases the expression of the galanin gene in the hypothalamus of rats.
Brain research. Molecular brain research 2003;119(2):152-9.
2003: Hiroyoshi Sei; Hiroaki Fujihara; Yoichi Ueta; Kyoji Morita; Kunio Kitahama; Yusuke Morita
Single eight-hour shift of light-dark cycle increases brain-derived neurotrophic factor protein levels in the rat hippocampus.
Life sciences 2003;73(1):53-9.
2003: Kyoji Morita; Aki Kuwada; Hiroaki Fujihara; Yusuke Morita; Hiroyoshi Sei
Changes in the expression of steroid metabolism-related genes in rat adrenal glands during selective REM sleep deprivation.
Life sciences 2003;72(17):1973-82.
2003: Hiroaki Fujihara; Hiroyoshi Sei; Yusuke Morita; Yoichi Ueta; Kyoji Morita
Short-term sleep disturbance enhances brain-derived neurotrophic factor gene expression in rat hippocampus by acting as internal stressor.
Journal of molecular neuroscience : MN 2003;21(3):223-32.
2003: Hiroyoshi Sei; A Sano; K Oishi; Hiroaki Fujihara; H Kobayashi; N Ishida; Y Morita
Increase of hippocampal acetylcholine release at the onset of dark phase is suppressed in a mutant mice model of evening-type individuals.
Neuroscience 2003;117(4):785-9.
2002: Mie Sakata; Hiroyoshi Sei; Kazunori Toida; Hiroaki Fujihara; Ryo Urushihara; Yusuke Morita
Mesolimbic dopaminergic system is involved in diurnal blood pressure regulation.
Brain research 2002;928(1-2):194-201.
2002: Kyoji Morita; Aki Kuwada; Hiroaki Fujihara; Yusuke Morita; Hiroyoshi Sei
Influence of sleep disturbance on steroid 5alpha-reductase mRNA levels in rat brain.
Neuroscience 2002;115(2):341-8.