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Nobuhiro Fujii

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Shin-Ichi Yokota; Nobuhiro Fujii; Nariaki Toita; Soh Yamamoto; Mutsuko Konno
Positive relationship between a polymorphism in Helicobacter pylori neutrophil-activating protein a gene and iron-deficiency anemia.
Shin-Ichi Yokota; Osamu Kuwahara; Yasuo Ohkoshi; Tamaki Okabayashi; Torahiko Okubo; Toyotaka Sato; Yutaka Tamura; Nobuhiro Fujii
Prevalence of fluoroquinolone-resistant Escherichia coli O25:H4-ST131 (CTX-M-15-nonproducing) strains isolated in Japan.
Shigeru Ariki; Nobuhiro Fujii; Shinsei Gasa; Takashi Kojima; Yuichiro Kurimura; Chiaki Nishitani; Atsushi Saito; Norimasa Sawada; Takeyuki Shimizu; Motoko Takahashi; Yoshio Kuroki
Pulmonary collectins play distinct roles in host defense against Mycobacterium avium.

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2013: Shin-Ichi Yokota; Nobuhiro Fujii; Nariaki Toita; Soh Yamamoto; Mutsuko Konno
Positive relationship between a polymorphism in Helicobacter pylori neutrophil-activating protein a gene and iron-deficiency anemia.
Helicobacter 2013;18(2):112-6.
2012: Shin-Ichi Yokota; Osamu Kuwahara; Yasuo Ohkoshi; Tamaki Okabayashi; Torahiko Okubo; Toyotaka Sato; Yutaka Tamura; Nobuhiro Fujii
Prevalence of fluoroquinolone-resistant Escherichia coli O25:H4-ST131 (CTX-M-15-nonproducing) strains isolated in Japan.
Chemotherapy 2012;58(1):52-9.
2011: Shigeru Ariki; Nobuhiro Fujii; Shinsei Gasa; Takashi Kojima; Yuichiro Kurimura; Chiaki Nishitani; Atsushi Saito; Norimasa Sawada; Takeyuki Shimizu; Motoko Takahashi; Yoshio Kuroki
Pulmonary collectins play distinct roles in host defense against Mycobacterium avium.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(5):2586-94.
2011: Tamaki Okabayashi; Hiroyuki Tsutsumi; Shin-Ichi Yokota; Nobuhiro Fujii; Tetsuo Himi; Tadaatsu Imaizumi; Takashi Kojima; Tomoyuki Masaki; Norimasa Sawada
Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells.
Virus research 2011;160(1-2):360-6.
2011: Tomoyuki Masaki; Masaki Murata; Takafumi Ninomiya; Kazufumi Obata; Noriko Ogasawara; Tsuyoshi Ohkuni; Tamaki Okabayashi; Jun Fuchimoto; Nobuhiro Fujii; Tetsuo Himi; Satoshi Hirakawa; Takashi Kojima; Akira Takasawa; Satoshi Tanaka; Hiroyuki Tsutsumi; Norimasa Sawada
A nuclear factor-κB signaling pathway via protein kinase C δ regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells.
Molecular biology of the cell 2011;22(13):2144-56.
2011: Hiroyuki Tsutsumi; Shinichi Yokota; Nobuhiro Fujii; Tetsuo Himi; Satoshi Hirakawa; Takashi Kojima; Tomoyuki Masaki; Tamaki Okabayashi; Norimasa Sawada
Respiratory syncytial virus infection and the tight junctions of nasal epithelial cells.
Advances in oto-rhino-laryngology 2011;72():153-6.
2010: Shin-Ichi Yokota; Tamaki Okabayashi; Yuko Yoto; Tsukasa Hori; Hiroyuki Tsutsumi; Nobuhiro Fujii
Fosfomycin suppresses RS-virus-induced Streptococcus pneumoniae and Haemophilus influenzae adhesion to respiratory epithelial cells via the platelet-activating factor receptor.
FEMS microbiology letters 2010;310(1):84-90.
2010: Shuji Uemura; Shin-Ichi Yokota; Hirotoshi Mizuno; Eiji Sakawaki; Keigo Sawamoto; Kunihiko Maekawa; Katsutoshi Tanno; Kazuhisa Mori; Yasufumi Asai; Nobuhiro Fujii
Acquisition of a transposon encoding extended-spectrum beta-lactamase SHV-12 by Pseudomonas aeruginosa isolates during the clinical course of a burn patient.
Antimicrobial agents and chemotherapy 2010;54(9):3956-9.
2010: Shin-Ichi Yokota; Nobuhiro Fujii
Immunomodulatory activity of extracellular heat shock proteins and their autoantibodies.
Microbiology and immunology 2010;54(5):299-307.
2010: Shin-ichi Yokota; Susumu Chiba; Hiroyasu Furuyama; Nobuhiro Fujii
Cerebrospinal fluids containing anti-HSP70 autoantibodies from multiple sclerosis patients augment HSP70-induced proinflammatory cytokine production in monocytic cells.
Journal of neuroimmunology 2010;218(1-2):129-33.
2010: Shin-Ichi Yokota; Tamaki Okabayashi; Nobuhiro Fujii
The battle between virus and host: modulation of Toll-like receptor signaling pathways by virus infection.
Mediators of inflammation 2010;2010():184328.
2010: Shin-Ichi Yokota; Tamaki Okabayashi; Michael Rehli; Nobuhiro Fujii; Ken-Ichi Amano
Helicobacter pylori lipopolysaccharides upregulate toll-like receptor 4 expression and proliferation of gastric epithelial cells via the MEK1/2-ERK1/2 mitogen-activated protein kinase pathway.
Infection and immunity 2010;78(1):468-76.
2009: Shin-ichi Yokota; Yasuo Ohkoshi; Nobuhiro Fujii
Susceptibility and bactericidal activity of 8 oral quinolones against conventional-fluoroquinolone-resistant Streptococcus pneumoniae clinical isolates.
Diagnostic microbiology and infectious disease 2009;65(1):76-80.
2009: Koichi Hashimoto; Kei Ishibashi; Ken Ishioka; Dongchi Zhao; Masatoki Sato; Shinichiro Ohara; Yusaku Abe; Yukihiko Kawasaki; Yuka Sato; Shin-Ichi Yokota; Nobuhiro Fujii; Ray Stokes Peebles; Mitsuaki Hosoya; Tatsuo Suzutani
RSV replication is attenuated by counteracting expression of the suppressor of cytokine signaling (SOCS) molecules.
Virology 2009;391(2):162-70.
2009: Shin-ichi Yokota; Yasuo Ohkoshi; Kiyoshi Sato; Nobuhiro Fujii
High prevalence of beta-lactam-resistant Haemophilus influenzae type b isolates derived from respiratory tract specimens in Japanese patients.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2009;13(5):584-8.
2009: Tamaki Okabayashi; Shin-Ichi Yokota; Yuko Yoto; Hiroyuki Tsutsumi; Nobuhiro Fujii
Fosfomycin suppresses chemokine induction in airway epithelial cells infected with respiratory syncytial virus.
Clinical and vaccine immunology : CVI 2009;16(6):859-65.
2009: Atsushi Harimaya; Nobuhiro Fujii; Tetsuo Himi
Preliminary study of proinflammatory cytokines and chemokines in the middle ear of acute otitis media due to Alloiococcus otitidis.
International journal of pediatric otorhinolaryngology 2009;73(5):677-80.
2008: Atsushi Harimaya; Shin-ichi Yokota; Kiyoshi Sato; Tetsuo Himi; Nobuhiro Fujii
Remarkably high prevalence of fts I gene mutations in Haemophilus influenzae isolates from upper respiratory tract infections in children of the Sapporo district, Japan.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2008;14(3):223-7.
2008: Tamaki Okabayashi; Shin-ichi Yokota; Yasuo Ohkoshi; Hironori Ohuchi; Yasuhiro Yoshida; Masayuki Kikuchi; Koichi Yano; Nobuhiro Fujii
Occurrence of norovirus infections unrelated to norovirus outbreaks in an asymptomatic food handler population.
Journal of clinical microbiology 2008;46(6):1985-8.
2008: Yasuo Ohkoshi; Shin-Ichi Yokota; Kiyoshi Sato; Tasuku Hayashi; Keiko Matsuda; Osamu Kuwahara; Hirotsugu Akizawa; Nobuhiro Fujii
Antibiotic susceptibility of Haemophilus influenzae strains isolated from various clinical sources in Hokkaido Prefecture, Japan.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2008;14(2):93-8.
2008: Shin-ichi Yokota; Mutsuko Konno; Emi Mino; Kohei Sato; Michiko Takahashi; Nobuhiro Fujii
Enhanced Fe ion-uptake activity in Helicobacter pylori strains isolated from patients with iron-deficiency anemia.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;46(4):e31-3.
2008: Shin-ichi Yokota; Yasuo Ohkoshi; Kiyoshi Sato; Nobuhiro Fujii
Emergence of fluoroquinolone-resistant Haemophilus influenzae strains among elderly patients but not among children.
Journal of clinical microbiology 2008;46(1):361-5.
2008: Shin-ichi Yokota; Tamaki Okabayashi; Noriko Yokosawa; Nobuhiro Fujii
Measles virus P protein suppresses Toll-like receptor signal through up-regulation of ubiquitin-modifying enzyme A20.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(1):74-83.
2007: Shin-ichi Yokota; Takahiro Ohnishi; Masashi Muroi; Kenichi Tanamoto; Nobuhiro Fujii; Ken-ichi Amano
Highly-purified Helicobacter pylori LPS preparations induce weak inflammatory reactions and utilize Toll-like receptor 2 complex but not Toll-like receptor 4 complex.
FEMS immunology and medical microbiology 2007;51(1):140-8.
2007: Atsushi Harimaya; Jun-ichi Koizumi; Nobuhiro Fujii; Tetsuo Himi
Interleukin-8 induction via NF-kappaB, p38 mitogen-activated protein kinase and extracellular signal-regulated kinase 1/2 pathways in human peripheral blood mononuclear cells by Alloiococcus otitidis.
International journal of pediatric otorhinolaryngology 2007;71(9):1465-70.
2007: Atsushi Harimaya; Shin-ichi Yokota; Kiyoshi Sato; Norikazu Yamazaki; Tetsuo Himi; Nobuhiro Fujii
High prevalence of erythromycin resistance and macrolide-resistance genes, mefA and ermB, in Streptococcus pneumoniae isolates from the upper respiratory tracts of children in the Sapporo district, Japan.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2007;13(4):219-23.
2007: Tomokazu Indoh; Shin-ichi Yokota; Tamaki Okabayashi; Noriko Yokosawa; Nobuhiro Fujii
Suppression of NF-kappaB and AP-1 activation in monocytic cells persistently infected with measles virus.
Virology 2007;361(2):294-303.
2007: Shin-Ichi Yokota; Nobuhiro Fujii
Contributions of the lipopolysaccharide outer core oligosaccharide region on the cell surface properties of Pseudomonas aeruginosa.
Comparative immunology, microbiology and infectious diseases 2007;30(2):97-109.
2007: Atsushi Harimaya; Ryuta Takada; Tetsuo Himi; Shin-ichi Yokota; Nobuhiro Fujii
Evidence of local antibody response against Alloiococcus otitidis in the middle ear cavity of children with otitis media.
FEMS immunology and medical microbiology 2007;49(1):41-5.
2007: Shin-Ichi Yokota; Atsushi Harimaya; Kiyoshi Sato; Yukihiro Somekawa; Tetsuo Himi; Nobuhiro Fujii
Colonization and turnover of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in otitis-prone children.
Microbiology and immunology 2007;51(2):223-30.
2006: Atsushi Harimaya; Shin-ichi Yokota; Kiyoshi Sato; Jun-ichi Koizumi; Norikazu Yamazaki; Tetsuo Himi; Nobuhiro Fujii
Alterations of pbp1a, pbp2b, and pbp2x in Streptococcus pneumoniae isolates from children with otolaryngological infectious disease in the Sapporo district of Japan.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2006;12(6):366-71.
2006: Hiroyasu Furuyama; Susumu Chiba; Tamaki Okabayashi; Shin-ichi Yokota; Michio Nonaka; Tomihiro Imai; Nobuhiro Fujii; Hiroyuki Matsumoto
Single nucleotide polymorphisms and functional analysis of MxA promoter region in multiple sclerosis.
Journal of the neurological sciences 2006;249(2):153-7.
2006: Kei Ono; Chiaki Nishitani; Hiroaki Mitsuzawa; Takeyuki Shimizu; Hitomi Sano; Hiroshi Suzuki; Tatsuhiko Kodama; Nobuhiro Fujii; Koichi Fukase; Koichi Hirata; Yoshio Kuroki
Mannose-binding lectin augments the uptake of lipid A, Staphylococcus aureus, and Escherichia coli by Kupffer cells through increased cell surface expression of scavenger receptor A.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5517-23.
2006: Masanori Konishi; Chiaki Nishitani; Hiroaki Mitsuzawa; Takeyuki Shimizu; Hitomi Sano; Atsushi Harimaya; Nobuhiro Fujii; Tetsuo Himi; Yoshio Kuroki
Alloiococcus otitidis is a ligand for collectins and Toll-like receptor 2, and its phagocytosis is enhanced by collectins.
European journal of immunology 2006;36(6):1527-36.
2006: Atsushi Harimaya; Ryuta Takada; Yukihiro Somekawa; Nobuhiro Fujii; Tetsuo Himi
High frequency of Alloiococcus otitidis in the nasopharynx and in the middle ear cavity of otitis-prone children.
International journal of pediatric otorhinolaryngology 2006;70(6):1009-14.
2006: Tamaki Okabayashi; Hiroaki Kariwa; Shin-ichi Yokota; Shigeo Iki; Tomokazu Indoh; Noriko Yokosawa; Ikuo Takashima; Hiroyuki Tsutsumi; Nobuhiro Fujii
Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections.
Journal of medical virology 2006;78(4):417-24.
2006: Shin-ichi Yokota; Seiji Minota; Nobuhiro Fujii
Anti-HSP auto-antibodies enhance HSP-induced pro-inflammatory cytokine production in human monocytic cells via Toll-like receptors.
International immunology 2006;18(4):573-80.
2006: Nobuhiro Fujii; Shin-ichi Yokota; Noriko Yokosawa; Tamaki Okabayashi
[Molecular mechanisms for suppression of interferon system by HSV-1 infection].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 3():171-7.
2006: Atsushi Harimaya; Ryuta Takada; Panu Hendolin; Nobuhiro Fujii; Jukka Ylikoski; Tetsuo Himi
High incidence of Alloiococcus otitidis in children with otitis media, despite treatment with antibiotics.
Journal of clinical microbiology 2006;44(3):946-9.
2006: Susumu Chiba; Shin-ichi Yokota; Kazumi Yonekura; Shingo Tanaka; Hiroyasu Furuyama; Hiroshi Kubota; Nobuhiro Fujii; Hiroyuki Matsumoto
Autoantibodies against HSP70 family proteins were detected in the cerebrospinal fluid from patients with multiple sclerosis.
Journal of the neurological sciences 2006;241(1-2):39-43.
2005: Shigeo Iki; Shin-ichi Yokota; Tamaki Okabayashi; Noriko Yokosawa; Kyosuke Nagata; Nobuhiro Fujii
Serum-dependent expression of promyelocytic leukemia protein suppresses propagation of influenza virus.
Virology 2005;343(1):106-15.
2005: Atsushi Harimaya; Jussi Tarkkanen; Petri Mattila; Nobuhiro Fujii; Jukka Ylikoski; Tetsuo Himi
Difference in cytokine production and cell activation between adenoidal lymphocytes and peripheral blood lymphocytes of children with otitis media.
Clinical and diagnostic laboratory immunology 2005;12(9):1130-4.
2005: Shin-ichi Yokota; Noriko Yokosawa; Tamaki Okabayashi; Tatsuo Suzutani; Nobuhiro Fujii
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 confers efficient viral replication.
Virology 2005;338(1):173-81.
2005: Mutsuko Konno; Nobuhiro Fujii; Shin-ichi Yokota; Kiyoshi Sato; Michiko Takahashi; Kohei Sato; Emi Mino; Toshiro Sugiyama
Five-year follow-up study of mother-to-child transmission of Helicobacter pylori infection detected by a random amplified polymorphic DNA fingerprinting method.
Journal of clinical microbiology 2005;43(5):2246-50.
2005: Atsushi Harimaya; Tetsuo Himi; Nobuhiro Fujii; Jussi Tarkkanen; Petteri Carlson; Jukka Ylikoski; Petri Mattila
Induction of CD69 expression and Th1 cytokines release from human peripheral blood lymphocytes after in vitro stimulation with Alloiococcus otitidis and three middle ear pathogens.
FEMS immunology and medical microbiology 2005;43(3):385-92.
2004: Nobuhiro Fujii; Shin-Ichi Yokota; Noriko Yokosawa; Tamaki Okabayashi
[Molecular mechanisms for suppression of interferon signal transduction pathways caused by viral infections].
Uirusu 2004;54(2):169-78.
2004: Kazumi Yonekura; Shin-ichi Yokota; Shingo Tanaka; Hiroshi Kubota; Nobuhiro Fujii; Hiroyuki Matsumoto; Susumu Chiba
Prevalence of anti-heat shock protein antibodies in cerebrospinal fluids of patients with Guillain-Barré syndrome.
Journal of neuroimmunology 2004;156(1-2):204-9.
2004: Shin-ichi Yokota; Kiyoshi Sato; Shigeru Yoshida; Tasuku Hayashi; Keiko Matsuda; Osamu Kuwahara; Satoshi Habadera; Kazuhiko Kobayashi; Ryo Ueno; Hirotsugu Akizawa; Nobuhiro Fujii
Macrolide-resistant Streptococcus pneumoniae clinical isolates that occur in Hokkaido prefecture, Japan.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2004;10(5):284-7.
2004: Toshiaki Shimizu; Shin-ichi Yokota; Satoshi Takahashi; Yasuharu Kunishima; Koh Takeyama; Naoya Masumori; Atsushi Takahashi; Masanori Matsukawa; Naoki Itoh; Taiji Tsukamoto; Nobuhiro Fujii
Membrane-anchored CD14 is important for induction of interleukin-8 by lipopolysaccharide and peptidoglycan in uroepithelial cells.
Clinical and diagnostic laboratory immunology 2004;11(5):969-76.
2004: Kazumi Kudo; Hitomi Sano; Hiroki Takahashi; Koji Kuronuma; Shin-ichi Yokota; Nobuhiro Fujii; Ken-ichi Shimada; Ikuya Yano; Yoshio Kumazawa; Dennis R Voelker; Shosaku Abe; Yoshio Kuroki
Pulmonary collectins enhance phagocytosis of Mycobacterium avium through increased activity of mannose receptor.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7592-602.
2004: Shin-ichi Yokota; Noriko Yokosawa; Tamaki Okabayashi; Tatsuo Suzutani; Shunsuke Miura; Kowichi Jimbow; Nobuhiro Fujii
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
Journal of virology 2004;78(12):6282-6.
2004: Koji Kuronuma; Hitomi Sano; Kazunori Kato; Kazumi Kudo; Naoki Hyakushima; Shin-ichi Yokota; Hiroki Takahashi; Nobuhiro Fujii; Hiroshi Suzuki; Tatsuhiko Kodama; Shosaku Abe; Yoshio Kuroki
Pulmonary surfactant protein A augments the phagocytosis of Streptococcus pneumoniae by alveolar macrophages through a casein kinase 2-dependent increase of cell surface localization of scavenger receptor A.
The Journal of biological chemistry 2004;279(20):21421-30.
2004: Shin-ichi Yokota; Kiyoshi Sato; Shigeru Yoshida; Nobuhiro Fujii
[Molecular epidemiology of fluoroquinolone-resistant Streptococcus pneumoniae in Japan].
Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases 2004;78(5):428-34.
2004: Shin-ichi Yokota; Tamaki Okabayashi; Noriko Yokosawa; Nobuhiro Fujii
Growth arrest of epithelial cells during measles virus infection is caused by upregulation of interferon regulatory factor 1.
Journal of virology 2004;78(9):4591-8.
2004: Norihisa Horita; Shin-Ichi Yokota; Shigeto Fuse; Motoki Takamuro; Hideshi Tomita; Kiyoshi Sato; Nobuhiro Fujii; Hiroyuki Tsutsumi
The throat flora and its mitogenic activity in patients with Kawasaki disease.
Microbiology and immunology 2004;48(11):899-903.
2003: Shin-ichi Yokota; Noriko Yokosawa; Toru Kubota; Tamaki Okabayashi; Satoru Arata; Nobuhiro Fujii
Suppression of thermotolerance in mumps virus-infected cells is caused by lack of HSP27 induction contributed by STAT-1.
The Journal of biological chemistry 2003;278(43):41654-60.
2003: Shin-ichi Yokota; Hiroshi Kubota; Yasuhiro Matsuoka; Motoko Naitoh; Daisuke Hirata; Seiji Minota; Hiroki Takahashi; Nobuhiro Fujii; Kazuhiro Nagata
Prevalence of HSP47 antigen and autoantibodies to HSP47 in the sera of patients with mixed connective tissue disease.
Biochemical and biophysical research communications 2003;303(2):413-8.
2003: Noriyuki Yonekura; S Yokota; K Yonekura; Hironari Dehari; S Arata; Geniku Kohama; Nobuhiro Fujii
Interferon-gamma downregulates Hsp27 expression and suppresses the negative regulation of cell death in oral squamous cell carcinoma lines.
Cell death and differentiation 2003;10(3):313-22.
2003: Shin-ichi Yokota; Hiroyuki Saito; Toru Kubota; Noriko Yokosawa; Ken-ichi Amano; Nobuhiro Fujii
Measles virus suppresses interferon-alpha signaling pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex.
Virology 2003;306(1):135-46.
2002: Noriko Yokosawa; Shin-Ichi Yokota; Toru Kubota; Nobuhiro Fujii
C-terminal region of STAT-1alpha is not necessary for its ubiquitination and degradation caused by mumps virus V protein.
Journal of virology 2002;76(24):12683-90.
2002: Toru Kubota; Noriko Yokosawa; Shin-ichi Yokota; Nobuhiro Fujii
Association of mumps virus V protein with RACK1 results in dissociation of STAT-1 from the alpha interferon receptor complex.
Journal of virology 2002;76(24):12676-82.
2002: Shin-Ichi Yokota; Kiyoshi Sato; Osamu Kuwahara; Satoshi Habadera; Naoyuki Tsukamoto; Hironori Ohuchi; Hirotsugu Akizawa; Tetsuo Himi; Nobuhiro Fujii
Fluoroquinolone-resistant Streptococcus pneumoniae strains occur frequently in elderly patients in Japan.
Antimicrobial agents and chemotherapy 2002;46(10):3311-5.
2002: Susumu Chiba; T Sugiyama; Kazumi Yonekura; Shingo Tanaka; Hiroyuki Matsumoto; Nobuhiro Fujii; S Ebisu; K Sekiguchi
An antibody to VacA of Helicobacter pylori in cerebrospinal fluid from patients with Guillain-Barre syndrome.
Journal of neurology, neurosurgery, and psychiatry 2002;73(1):76-8.
2001: Shin-Ichi Yokota; Noriko Yokosawa; Toru Kubota; Tatsuo Suzutani; I Yoshida; S Miura; Kowichi Jimbow; Nobuhiro Fujii
Herpes simplex virus type 1 suppresses the interferon signaling pathway by inhibiting phosphorylation of STATs and janus kinases during an early infection stage.
Virology 2001;286(1):119-24.
2001: Toru Kubota; Noriko Yokosawa; Shin-Ichi Yokota; Nobuhiro Fujii
C terminal CYS-RICH region of mumps virus structural V protein correlates with block of interferon alpha and gamma signal transduction pathway through decrease of STAT 1-alpha.
Biochemical and biophysical research communications 2001;283(1):255-9.
2000: Tetsuo Himi; H Kita; Hiroaki Mitsuzawa; Atsushi Harimaya; Jussi Tarkkanen; Panu Hendolin; Jukka Ylikoski; Nobuhiro Fujii
Effect of Alloiococcus otitidis and three pathogens of otitis media in production of interleukin-12 by human monocyte cell line.
FEMS immunology and medical microbiology 2000;29(2):101-6.
2000: K Tsuzuki; R Fukatsu; Haruyasu Yamaguchi; M Tateno; K Imai; Nobuhiro Fujii; T Yamauchi
Transthyretin binds amyloid beta peptides, Abeta1-42 and Abeta1-40 to form complex in the autopsied human kidney - possible role of transthyretin for abeta sequestration.
Neuroscience letters 2000;281(2-3):171-4.
2000: H Kita; Tetsuo Himi; Nobuhiro Fujii; Jukka Ylikoski
Interleukin-8 secretion of human epithelial and monocytic cell lines induced by middle ear pathogens.
Microbiology and immunology 2000;44(6):511-7.
1999: Nobuhiro Fujii; Noriko Yokosawa; S Shirakawa
Suppression of interferon response gene expression in cells persistently infected with mumps virus, and restoration from its suppression by treatment with ribavirin.
Virus research 1999;65(2):175-85.
1999: Yasushi Hariya; S Shirakawa; Noriyuki Yonekura; Noriko Yokosawa; Geniku Kohama; Nobuhiro Fujii
Augmentation of verotoxin-induced cytotoxicity/apoptosis by interferon is repressed in cells persistently infected with mumps virus.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(5):479-85.
1999: Nobuhiro Fujii; Noriko Yokosawa
[Dysfunction of host defence systems caused by virus infection].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(1):8-18.
1998: Nobuyuki Sasaki; R Fukatsu; K Tsuzuki; Yorihide Hayashi; Taku Yoshida; Nobuhiro Fujii; T Koike; I Wakayama; R Yanagihara; R Garruto; N Amano; Zenji Makita
Advanced glycation end products in Alzheimer's disease and other neurodegenerative diseases.
The American journal of pathology 1998;153(4):1149-55.
1998: K Kimura; T Kubota; I Ohishi; Emiko Isogai; Hiroshi Isogai; Nobuhiro Fujii
The gene for component-II of botulinum C2 toxin.
Veterinary microbiology 1998;62(1):27-34.
1998: Yorihide Hayashi; R Fukatsu; K Tsuzuki; Taku Yoshida; Nobuyuki Sasaki; K Kimura; Haruyasu Yamaguchi; Peter St George-Hyslop; Nobuhiro Fujii; N Takahata
Evidence for presenilin-1 involvement in amyloid angiopathy in the Alzheimer's disease-affected brain.
Brain research 1998;789(2):307-14.
1998: K Kimura; H Kimura; Noriko Yokosawa; Hiroshi Isogai; Emiko Isogai; S Kozaki; A Miyamoto; T Nishikawa; H Ohshika; Toru Kubota; Nobuhiro Fujii
Negative chronotropic effect of botulinum toxin on neonatal rat cardiac myocytes.
Biochemical and biophysical research communications 1998;244(1):275-9.
1998: T Kubota; Noriyuki Yonekura; Yasushi Hariya; Emiko Isogai; Hiroshi Isogai; K Amano; Nobuhiro Fujii
Gene arrangement in the upstream region of Clostridium botulinum type E and Clostridium butyricum BL6340 progenitor toxin genes is different from that of other types.
FEMS microbiology letters 1998;158(2):215-21.
1998: Noriko Yokosawa; Toru Kubota; Nobuhiro Fujii
Poor induction of interferon-induced 2',5'-oligoadenylate synthetase (2-5 AS) in cells persistently infected with mumps virus is caused by decrease of STAT-1 alpha.
Archives of virology 1998;143(10):1985-92.
1997: Y Aizawa; R Fukatsu; Y Takamaru; K Tsuzuki; H Chiba; K Kobayashi; Nobuhiro Fujii; N Takahata
Amino-terminus truncated apolipoprotein E is the major species in amyloid deposits in Alzheimer's disease-affected brains: a possible role for apolipoprotein E in Alzheimer's disease.
Brain research 1997;768(1-2):208-14.
1997: Taku Yoshida; R Fukatsu; K Tsuzuki; Y Aizawa; Yorihide Hayashi; Nobuyuki Sasaki; Y Takamaru; Nobuhiro Fujii; N Takahata
Amyloid precursor protein, A beta and amyloid-associated proteins involved in chloroquine retinopathy in rats--immunopathological studies.
Brain research 1997;764(1-2):283-8.
1997: Nobuhiro Fujii; T Kubota; S Nakata; S Chiba; H Ito
[Frequency of verocytotoxin 2 (VT2) neutralizing activity in human sera].
Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1997;71(4):348-9.
1997: T Kubota; T Watanabe; Noriko Yokosawa; K Tsuzuki; Tomokazu Indoh; K Moriishi; K Sanda; Y Maki; K Inoue; Nobuhiro Fujii
Epitope regions in the heavy chain of Clostridium botulinum type E neurotoxin recognized by monoclonal antibodies.
Applied and environmental microbiology 1997;63(4):1214-8.
1997: K Tsuzuki; R Fukatsu; Yorihide Hayashi; Taku Yoshida; Nobuyuki Sasaki; Y Takamaru; Haruyasu Yamaguchi; M Tateno; Nobuhiro Fujii; N Takahata
Amyloid beta protein and transthyretin, sequestrating protein colocalize in normal human kidney.
Neuroscience letters 1997;222(3):163-6.
1997: K Tsuzuki; R Fukatsu; Y Takamaru; Taku Yoshida; Yorihide Hayashi; K Kobayashi; Nobuhiro Fujii; N Takahata
Snake coiled fibres in rat soleus muscle in chloroquine induced myopathy share immunohistochemical characteristics with amyloid depositions in Alzheimer's disease brain tissue.
International journal of experimental pathology 1997;78(1):1-8.
1997: Noriko Yokosawa; Tomokazu Indoh; T Kubota; T Yashiki; Nobuhiro Fujii
Suppressed induction of 2-5AS in cells with HTLV-I is not associated with the fluctuation of IFN-receptor, IFN-regulatory factors (IRF-1 and IRF-2) or STAT-1 alpha.
Microbiology and immunology 1997;41(1):63-6.