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Sadaki Fujimoto

Research Profile

Living Beings

Rats
Mouse

Chemicals & Drugs

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Reverse Transcriptase Polymerase Chain Reaction

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Kentaro Nishida; Akihiro Ohishi; Hiroto Okuda; Tsunetoshi Nakatani; Sadaki Fujimoto; Youichirou Higashi; Takaaki Matsuo; Kazuki Nagasawa
Mitochondrial dysfunction is involved in P2X7 receptor-mediated neuronal cell death.
Akiko Tanaka; Sadaki Fujimoto; Youichirou Higashi; Kentaro Nishida; Takeshi Nishiura; Hiroto Okuda; Kazuki Nagasawa
Peroxynitrite treatment reduces adenosine uptake via the equilibrative nucleoside transporter in rat astrocytes.
Hiroto Okuda; Youichirou Higashi; Kentaro Nishida; Sadaki Fujimoto; Kazuki Nagasawa
Contribution of P2X7 receptors to adenosine uptake by cultured mouse astrocytes.

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All Publications

2012: Kentaro Nishida; Akihiro Ohishi; Hiroto Okuda; Tsunetoshi Nakatani; Sadaki Fujimoto; Youichirou Higashi; Takaaki Matsuo; Kazuki Nagasawa
Mitochondrial dysfunction is involved in P2X7 receptor-mediated neuronal cell death.
Journal of neurochemistry 2012;122(6):1118-28.
2011: Akiko Tanaka; Sadaki Fujimoto; Youichirou Higashi; Kentaro Nishida; Takeshi Nishiura; Hiroto Okuda; Kazuki Nagasawa
Peroxynitrite treatment reduces adenosine uptake via the equilibrative nucleoside transporter in rat astrocytes.
Neuroscience letters 2011;498(1):52-6.
2010: Hiroto Okuda; Youichirou Higashi; Kentaro Nishida; Sadaki Fujimoto; Kazuki Nagasawa
Contribution of P2X7 receptors to adenosine uptake by cultured mouse astrocytes.
Glia 2010;58(14):1757-65.
2010: Eri Suzuki; Hiroto Okuda; Kentaro Nishida; Sadaki Fujimoto; Kazuki Nagasawa
Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake.
Life sciences 2010;86(17-18):676-82.
2010: Miho Niitani; Kentaro Nishida; Hiroto Okuda; Katsuhito Nagai; Sadaki Fujimoto; Kazuki Nagasawa
Transport characteristics of mouse concentrative nucleoside transporter 1.
International journal of pharmaceutics 2010;388(1-2):168-74.
2009: Kazuki Nagasawa; Jun Miyaki; Yuka Kido; Youichirou Higashi; Kentaro Nishida; Sadaki Fujimoto
Possible involvement of PPAR gamma in the regulation of basal channel opening of P2X7 receptor in cultured mouse astrocytes.
Life sciences 2009;84(23-24):825-31.
2008: Kentaro Nishida; Eri Yasuda; Kazuki Nagasawa; Sadaki Fujimoto
Altered levels of oxidation and phospholipase C isozyme expression in the brains of theanine-administered rats.
Biological & pharmaceutical bulletin 2008;31(5):857-60.
2008: Eri Yasuda; Kazuki Nagasawa; Kentaro Nishida; Sadaki Fujimoto
Decreased expression of phospholipase C-beta 1 protein in endoplasmic reticulum stress-loaded neurons.
Biological & pharmaceutical bulletin 2008;31(4):719-21.
2007: Kazuki Nagasawa; Taichi Kakuda; Youichirou Higashi; Sadaki Fujimoto
Possible involvement of 12-lipoxygenase activation in glucose-deprivation/reload-treated neurons.
Neuroscience letters 2007;429(2-3):120-5.
2007: Kazuki Nagasawa; Fumio Kawasaki; Akiko Tanaka; Katsuhito Nagai; Sadaki Fujimoto
Characterization of guanine and guanosine transport in primary cultured rat cortical astrocytes and neurons.
Glia 2007;55(14):1397-404.
2007: Katsuhito Nagai; Kazuki Nagasawa; Yoji Kyotani; Natsuko Hifumi; Sadaki Fujimoto
Mouse equilibrative nucleoside transporter 2 (mENT2) transports nucleosides and purine nucleobases differing from human and rat ENT2.
Biological & pharmaceutical bulletin 2007;30(5):979-81.
2007: Katsuhito Nagai; Kazuki Nagasawa; Yukiko Kihara; Hiroto Okuda; Sadaki Fujimoto
Anticancer nucleobase analogues 6-mercaptopurine and 6-thioguanine are novel substrates for equilibrative nucleoside transporter 2.
International journal of pharmaceutics 2007;333(1-2):56-61.
2006: Katsuhito Nagai; Kazuki Nagasawa; Ryoko Matsunaga; Masumi Yamaji; Sadaki Fujimoto
Novel Na+ -independent and adenine-specific transport system for adenine in primary cultured rat cortical neurons.
Neuroscience letters 2006;407(3):244-8.
2006: Katsuhito Nagai; Kazuki Nagasawa; Mineto Koma; Ayumi Hotta; Sadaki Fujimoto
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.
Biochemical and biophysical research communications 2006;347(2):439-43.
2006: Kazuki Nagasawa; Junya Akagi; Mineto Koma; Taichi Kakuda; Katsuhito Nagai; Shun Shimohama; Sadaki Fujimoto
Transport and toxic mechanism for aluminum citrate in human neuroblastoma SH-SY5Y cells.
Life sciences 2006;79(1):89-97.
2006: Katsuhito Nagai; Kazuki Nagasawa; Mineto Koma; Yukiko Kihara; Sadaki Fujimoto
Contribution of an unidentified sodium-dependent nucleoside transport system to the uptake and cytotoxicity of anthracycline in mouse M5076 ovarian sarcoma cells.
Biochemical pharmacology 2006;71(5):565-73.
2005: Katsuhito Nagai; Kazuki Nagasawa; Sadaki Fujimoto
Transport mechanisms for adenosine and uridine in primary-cultured rat cortical neurons and astrocytes.
Biochemical and biophysical research communications 2005;334(4):1343-50.
2005: Naoki Imagawa; Kazuki Nagasawa; Katsuhito Nagai; Naoko Kawakami-Honda; Sadaki Fujimoto
Protein kinase C-independent pathway for NADPH oxidase activation in guinea pig peritoneal polymorphonuclear leukocytes by cytochalasin D.
Archives of biochemistry and biophysics 2005;438(2):119-24.
2005: Katsuhito Nagai; Kazuki Nagasawa; Sadaki Fujimoto
Uptake of the anthracycline pirarubicin into mouse M5076 ovarian sarcoma cells via a sodium-dependent nucleoside transport system.
Cancer chemotherapy and pharmacology 2005;55(3):222-30.
2005: Kazuki Nagasawa; Shingo Ito; Taichi Kakuda; Katsuhito Nagai; Ikumi Tamai; Akira Tsuji; Sadaki Fujimoto
Transport mechanism for aluminum citrate at the blood-brain barrier: kinetic evidence implies involvement of system Xc- in immortalized rat brain endothelial cells.
Toxicology letters 2005;155(2):289-96.
2004: Kazuki Nagasawa; Kentaro Nishida; Katsuhito Nagai; Shun Shimohama; Sadaki Fujimoto
Differential expression profiles of PLC-beta1 and -delta1 in primary cultured rat cortical neurons treated with N-methyl-D-aspartate and peroxynitrite.
Neuroscience letters 2004;367(2):246-9.
2004: Kazuki Nagasawa; Hiromitsu Aoki; Eri Yasuda; Katsuhito Nagai; Shun Shimohama; Sadaki Fujimoto
Possible involvement of group I mGluRs in neuroprotective effect of theanine.
Biochemical and biophysical research communications 2004;320(1):116-22.
2003: Kazuki Nagasawa; Sumiko Kintsuji; Hirokazu Nakanishi; Katsuhito Nagai; Sadaki Fujimoto
Bioavailability of a morphine suppository is increased after intracolostomal administration in colostoma-constructed rabbits.
International journal of pharmaceutics 2003;265(1-2):65-73.
2003: Kazuki Nagasawa; Katsuhito Nagai; Atsushi Ishimoto; Sadaki Fujimoto
Transport mechanism for lovastatin acid in bovine kidney NBL-1 cells: kinetic evidences imply involvement of monocarboxylate transporter 4.
International journal of pharmaceutics 2003;262(1-2):63-73.
2003: Kazuki Nagasawa; Hiroko Tanino; Shun Shimohama; Sadaki Fujimoto
Effects of hyperoxia and acrylonitrile on the phospholipase C isozyme protein levels in rat heart and brain.
Life sciences 2003;73(11):1453-62.
2003: Hiroaki Takemasa; Naoki Imagawa; Naoko Kawakami-Honda; Kazuki Nagasawa; Sadaki Fujimoto
Effect of phosphotyrosine proteins on phorbol myristate acetate-induced NADPH oxidase activation in guinea pig peritoneal polymorphonuclear leukocytes.
Biological & pharmaceutical bulletin 2003;26(7):1009-12.
2003: Katsuhito Nagai; Kazuki Nagasawa; Atsushi Ishimoto; Sadaki Fujimoto
Pirarubicin is taken up by a uridine-transportable sodium-dependent concentrative nucleoside transporter in Ehrlich ascites carcinoma cells.
Cancer chemotherapy and pharmacology 2003;51(6):512-8.
2002: Kazuki Nagasawa; Katsuhito Nagai; Yuji Sumitani; Yuka Moriya; Yuichi Muraki; Kohji Takara; Noriaki Ohnishi; Teruyoshi Yokoyama; Sadaki Fujimoto
Monocarboxylate transporter mediates uptake of lovastatin acid in rat cultured mesangial cells.
Journal of pharmaceutical sciences 2002;91(12):2605-13.
2002: Yuka Moriya; Tsutomu Nakamura; Masanori Horinouchi; Toshiyuki Sakaeda; Takao Tamura; Nobuo Aoyama; Toshiro Shirakawa; Akinobu Gotoh; Sadaki Fujimoto; Masafumi Matsuo; Masato Kasuga; Katsuhiko Okumura
Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects.
Biological & pharmaceutical bulletin 2002;25(10):1356-9.
2002: Kazuki Nagasawa; Hirokazu Nakanishi; Ryoji Yamamoto; Sumiko Kintsuji; Sadaki Fujimoto
Decreased bioavailability of carbamazepine suppository after its intrarectal and intracolostomal administration to rectal-resected or colostoma-constructed rabbits.
International journal of pharmaceutics 2002;241(2):375-84.
2001: Kazuki Nagasawa; Katsuhito Nagai; N Ohnishi; T Yokoyama; Sadaki Fujimoto
Contribution of specific transport systems to anthracycline transport in tumor and normal cells.
Current drug metabolism 2001;2(4):355-66.
2001: Kazuki Nagasawa; Hirokazu Nakanishi; T Matsuda; K Takara; N Ohnishi; T Yokoyama; Sadaki Fujimoto
Pharmacokinetics of dicrofenac after its intrarectal and intracolostomal administration to rabbits with rectal resection or colostoma construction.
Biopharmaceutics & drug disposition 2001;22(1):31-9.