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Charles Antzelevitch

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TOP 3
Charles Antzelevitch; Gan-Xin Yan; Sami Viskin
Rationale for the use of the terms J-wave syndromes and early repolarization.
Carlo Napolitano; Charles Antzelevitch
Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac voltage-dependent L-type calcium channel.
Serge Sicouri; Brittany Gianetti; Andrew C Zygmunt; Jonathan M Cordeiro; Charles Antzelevitch
Antiarrhythmic effects of simvastatin in canine pulmonary vein sleeve preparations.

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All Publications

2011: Charles Antzelevitch; Gan-Xin Yan; Sami Viskin
Rationale for the use of the terms J-wave syndromes and early repolarization.
Journal of the American College of Cardiology 2011;57(15):1587-90.
2011: Carlo Napolitano; Charles Antzelevitch
Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac voltage-dependent L-type calcium channel.
Circulation research 2011;108(5):607-18.
2011: Serge Sicouri; Brittany Gianetti; Andrew C Zygmunt; Jonathan M Cordeiro; Charles Antzelevitch
Antiarrhythmic effects of simvastatin in canine pulmonary vein sleeve preparations.
Journal of the American College of Cardiology 2011;57(8):986-93.
2011: Hector Barajas-Martinez; Dan Hu; Gustavo Ontiveros; Gabriel Caceres; Mayurika Desai; Elena Burashnikov; Jorge Scaglione; Charles Antzelevitch
Biophysical and molecular characterization of a novel de novo KCNJ2 mutation associated with Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia mimicry.
Circulation. Cardiovascular genetics 2011;4(1):51-7.
2010: Jonathan M Cordeiro; Guillermo J Perez; Nicole Schmitt; Ryan Pfeiffer; Vladislav V Nesterenko; Elena Burashnikov; Christian Veltmann; Martin Borggrefe; Christian Wolpert; Rainer Schimpf; Charles Antzelevitch
Overlapping LQT1 and LQT2 phenotype in a patient with long QT syndrome associated with loss-of-function variations in KCNQ1 and KCNH2.
Canadian journal of physiology and pharmacology 2010;88(12):1181-90.
2010: Elena Burashnikov; Ryan Pfeiffer; Hector Barajas-Martinez; Eva Delpón; Dan Hu; Mayurika Desai; Martin Borggrefe; Michel Häissaguerre; Ronald Kanter; Guido D Pollevick; Alejandra Guerchicoff; Ruben Laiño; Mark Marieb; Koonlawee Nademanee; Gi-Byoung Nam; Roberto Robles; Rainer Schimpf; Dwight D Stapleton; Sami Viskin; Stephen Winters; Christian Wolpert; Samuel Zimmern; Christian Veltmann; Charles Antzelevitch
Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death.
Heart rhythm : the official journal of the Heart Rhythm Society 2010;7(12):1872-82.
2010: Avishag Laish-Farkash; Michael Glikson; Dovrat Brass; Dina Marek-Yagel; Elon Pras; Nathan Dascal; Charles Antzelevitch; Eyal Nof; Haya Reznik; Michael Eldar; David Luria
A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.
Journal of cardiovascular electrophysiology 2010;21(12):1365-72.
2010: Alexander Burashnikov; Serge Sicouri; José M Di Diego; Luiz Belardinelli; Charles Antzelevitch
Synergistic effect of the combination of ranolazine and dronedarone to suppress atrial fibrillation.
Journal of the American College of Cardiology 2010;56(15):1216-24.
2010: Charles Antzelevitch; Hector Barajas-Martinez
A gain-of-function I(K-ATP) mutation and its role in sudden cardiac death associated with J-wave syndromes.
Heart rhythm : the official journal of the Heart Rhythm Society 2010;7(10):1472-4.
2010: Arthur A M Wilde; Pieter G Postema; José M Di Diego; Sami Viskin; Hiroshi Morita; Jeffrey M Fish; Charles Antzelevitch
The pathophysiological mechanism underlying Brugada syndrome: depolarization versus repolarization.
Journal of molecular and cellular cardiology 2010;49(4):543-53.
2010: Alexander Burashnikov; Luiz Belardinelli; Charles Antzelevitch
Acute dronedarone is inferior to amiodarone in terminating and preventing atrial fibrillation in canine atria.
Heart rhythm : the official journal of the Heart Rhythm Society 2010;7(9):1273-9.
2010: Chinmay Patel; Gan-Xin Yan; Charles Antzelevitch
Short QT syndrome: from bench to bedside.
Circulation. Arrhythmia and electrophysiology 2010;3(4):401-8.
2010: Alexander Burashnikov; Andrew C Zygmunt; Jose M Di Diego; Gunilla Linhardt; Leif Carlsson; Charles Antzelevitch
AZD1305 exerts atrial predominant electrophysiological actions and is effective in suppressing atrial fibrillation and preventing its reinduction in the dog.
Journal of cardiovascular pharmacology 2010;56(1):80-90.
2010: Serge Sicouri; Leif Carlsson; Charles Antzelevitch
Electrophysiologic and antiarrhythmic effects of AZD1305 in canine pulmonary vein sleeves.
The Journal of pharmacology and experimental therapeutics 2010;334(1):255-9.
2010: Poul Erik Bloch-Thomsen; Arne Johannessen; Christian Jons; Thomas Fritz Hansen; Jørgen K Kanters; Jens Haarbo; Jim Hansen; Liselotte Klint Christiansen; Peter Sogaard; Knud Saermark; Charles Antzelevitch
The role of local voltage potentials in outflow tract ectopy.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2010;12(6):850-60.
2010: Sami Viskin; Pieter G Postema; Zahurul A Bhuiyan; Raphael Rosso; Jonathan M Kalman; Jitendra K Vohra; Milton E Guevara-Valdivia; Manlio F Marquez; Evgeni Kogan; Bernard Belhassen; Michael Glikson; Boris Strasberg; Charles Antzelevitch; Arthur A M Wilde
The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome.
Journal of the American College of Cardiology 2010;55(18):1955-61.
2010: Charles Antzelevitch; Gan-Xin Yan
J wave syndromes.
Heart rhythm : the official journal of the Heart Rhythm Society 2010;7(4):549-58.
2010: Caroline Chamberland; Hector Barajas-Martinez; Volker Haufe; Marie-Hélène Fecteau; Jean-Francois Delabre; Alexander Burashnikov; Charles Antzelevitch; Olivier Lesur; Ahmed Chraibi; Philippe Sarret; Robert Dumaine
Modulation of canine cardiac sodium current by Apelin.
Journal of molecular and cellular cardiology 2010;48(4):694-701.
2010: Serge Sicouri; Aaron Glass; Marcela Ferreiro; Charles Antzelevitch
Transseptal dispersion of repolarization and its role in the development of Torsade de Pointes arrhythmias.
Journal of cardiovascular electrophysiology 2010;21(4):441-7.
2010: Charles Antzelevitch
M cells in the human heart.
Circulation research 2010;106(5):815-7.
2010: Alexander Burashnikov; Charles Antzelevitch
New developments in atrial antiarrhythmic drug therapy.
Nature reviews. Cardiology 2010;7(3):139-48.
2010: Dan Hu; Hector Barajas-Martinez; Vladislav V Nesterenko; Ryan Pfeiffer; Alejandra Guerchicoff; Jonathan M Cordeiro; Anne B Curtis; Guido D Pollevick; Yuesheng Wu; Elena Burashnikov; Charles Antzelevitch
Dual variation in SCN5A and CACNB2b underlies the development of cardiac conduction disease without Brugada syndrome.
Pacing and clinical electrophysiology : PACE 2010;33(3):274-85.
2010: Charles Antzelevitch; Alexander Burashnikov
Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation.
Annals of the New York Academy of Sciences 2010;1188():78-86.
2010: Serge Sicouri; Alexander Burashnikov; Luiz Belardinelli; Charles Antzelevitch
Synergistic electrophysiologic and antiarrhythmic effects of the combination of ranolazine and chronic amiodarone in canine atria.
Circulation. Arrhythmia and electrophysiology 2010;3(1):88-95.
2010: Gi-Byoung Nam; Kwan-Ho Ko; Jun Kim; Kyoung-Min Park; Kyoung-Suk Rhee; Kee-Joon Choi; You-Ho Kim; Charles Antzelevitch
Mode of onset of ventricular fibrillation in patients with early repolarization pattern vs. Brugada syndrome.
European heart journal 2010;31(3):330-9.
2010: Jamie D Kapplinger; David J Tester; Marielle Alders; Begoña Benito; Myriam Berthet; Josep Brugada; Pedro Brugada; Véronique Fressart; Alejandra Guerchicoff; Carole Harris-Kerr; Shiro Kamakura; Florence Kyndt; Tamara T Koopmann; Yoshihiro Miyamoto; Ryan Pfeiffer; Guido D Pollevick; Vincent Probst; Sven Zumhagen; Matteo Vatta; Jeffrey A Towbin; Wataru Shimizu; Eric Schulze-Bahr; Charles Antzelevitch; Salisbury Benjamin; Pascale Guicheney; Arthur A M Wilde; Ramon Brugada; Jean-Jacques Schott; Michael J Ackerman
An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing.
Heart rhythm : the official journal of the Heart Rhythm Society 2010;7(1):33-46.
2010: Jie Wu; Wataru Shimizu; Wei-Guang Ding; Seiko Ohno; Futoshi Toyoda; Hideki Itoh; Wei-Jin Zang; Yoshihiro Miyamoto; Shiro Kamakura; Hiroshi Matsuura; Koonlawee Nademanee; Josep Brugada; Pedro Brugada; Ramon Brugada; Matteo Vatta; Jeffrey A Towbin; Charles Antzelevitch; Minoru Horie
KCNE2 modulation of Kv4.3 current and its potential role in fatal rhythm disorders.
Heart rhythm : the official journal of the Heart Rhythm Society 2010;7(2):199-205.
2010: Eyal Nof; Alexander Burashnikov; Charles Antzelevitch
Cellular basis for atrial fibrillation in an experimental model of short QT1: implications for a pharmacological approach to therapy.
Heart rhythm : the official journal of the Heart Rhythm Society 2010;7(2):251-7.
2010: Eyal Nof; Charles Antzelevitch; Michael Glikson
The Contribution of HCN4 to normal sinus node function in humans and animal models.
Pacing and clinical electrophysiology : PACE 2010;33(1):100-6.
2010: Kirstine Calloe; Ewa Soltysinska; Thomas Jespersen; Alicia Lundby; Charles Antzelevitch; Søren-Peter Olesen; Jonathan M Cordeiro
Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle.
Journal of molecular and cellular cardiology 2010;48(1):191-200.
2009: Charles Antzelevitch; Alexander Burashnikov
Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation.
Journal of electrocardiology 2009;42(6):543-8.
2009: Sami Viskin; Raphael Rosso; Manlio F Márquez; Charles Antzelevitch
The acquired Brugada syndrome and the paradox of choice.
Heart rhythm : the official journal of the Heart Rhythm Society 2009;6(9):1342-4.
2009: Alexander Burashnikov; Charles Antzelevitch
New pharmacological strategies for the treatment of atrial fibrillation.
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 2009;14(3):290-300.
2009: Serge Sicouri; Luiz Belardinelli; Leif Carlsson; Charles Antzelevitch
Potent antiarrhythmic effects of chronic amiodarone in canine pulmonary vein sleeve preparations.
Journal of cardiovascular electrophysiology 2009;20(7):803-10.
2009: Dan Hu; Hector Barajas-Martinez; Elena Burashnikov; Michael Springer; Yuesheng Wu; Andras Varro; Ryan Pfeiffer; Tamara T Koopmann; Jonathan M Cordeiro; Alejandra Guerchicoff; Guido D Pollevick; Charles Antzelevitch
A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype.
Circulation. Cardiovascular genetics 2009;2(3):270-8.
2009: Alexander Burashnikov; Charles Antzelevitch
Atrial-selective sodium channel block for the treatment of atrial fibrillation.
Expert opinion on emerging drugs 2009;14(2):233-49.
2009: Jonathan M Cordeiro; Mark Marieb; Ryan Pfeiffer; Kirstine Calloe; Elena Burashnikov; Charles Antzelevitch
Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome.
Journal of molecular and cellular cardiology 2009;46(5):695-703.
2009: Sami Viskin; Arthur A M Wilde; Hanno L Tan; Charles Antzelevitch; Wataru Shimizu; Bernard Belhassen
Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registry.
Heart rhythm : the official journal of the Heart Rhythm Society 2009;6(3):401-4.
2009: Kirstine Calloe; Jonathan M Cordeiro; José M Di Diego; Rie Schultz Hansen; Morten Grunnet; Søren-Peter Olesen; Charles Antzelevitch
A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome.
Cardiovascular research 2009;81(4):686-94.
2009: Chinmay Patel; James F Burke; Harsh Patel; Prasad Gupta; Peter R Kowey; Charles Antzelevitch; Gan-Xin Yan
Is there a significant transmural gradient in repolarization time in the intact heart? Cellular basis of the T wave: a century of controversy.
Circulation. Arrhythmia and electrophysiology 2009;2(1):80-8.
2008: Andrés Ricardo Pérez Riera; Celso F Filho; Augusto H Uchida; Li Zhang; Charles Antzelevitch; Edgardo Schapachnik; Sergio Dubner; Celso Ferreira
Study of the extent of the information of cardiologists from São Paulo city, Brazil, regarding a low-prevalence entity: Brugada syndrome.
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 2008;13(4):352-63.
2008: Christian Wolpert; Christian Veltmann; Rainer Schimpf; Charles Antzelevitch; Ihor Gussak; Martin Borggrefe
Is a narrow and tall QRS complex an ECG marker for sudden death?
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(9):1339-45.
2008: Alexander Burashnikov; Charles Antzelevitch
Can inhibition of IKur promote atrial fibrillation?
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(9):1304-9.
2008: Charles Antzelevitch; Eyal Nof
Brugada syndrome: recent advances and controversies.
Current cardiology reports 2008;10(5):376-83.
2008: Hector M Barajas-Martínez; Dan Hu; Jonathan M Cordeiro; Yuesheng Wu; Richard J Kovacs; Henry Meltser; Hong Kui; Burashnikov Elena; Ramon Brugada; Charles Antzelevitch; Robert Dumaine
Lidocaine-induced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel.
Circulation research 2008;103(4):396-404.
2008: Alexander Burashnikov; Wataru Shimizu; Charles Antzelevitch
Fever accentuates transmural dispersion of repolarization and facilitates development of early afterdepolarizations and torsade de pointes under long-QT Conditions.
Circulation. Arrhythmia and electrophysiology 2008;1(3):202-8.
2008: Eva Delpón; Jonathan M Cordeiro; Lucía Núñez; Poul Erik Bloch Thomsen; Alejandra Guerchicoff; Guido D Pollevick; Yuesheng Wu; Jørgen K Kanters; Carsten Toftager Larsen; Jacob Hofman-Bang; Elena Burashnikov; Michael Christiansen; Charles Antzelevitch
Functional effects of KCNE3 mutation and its role in the development of Brugada syndrome.
Circulation. Arrhythmia and electrophysiology 2008;1(3):209-18.
2008: Alexander Burashnikov; Charles Antzelevitch
Atrial-selective sodium channel blockers: do they exist?
Journal of cardiovascular pharmacology 2008;52(2):121-8.
2008: Serge Sicouri; Aaron Glass; Luiz Belardinelli; Charles Antzelevitch
Antiarrhythmic effects of ranolazine in canine pulmonary vein sleeve preparations.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(7):1019-26.
2008: Jonathan M Cordeiro; M Mazza; R Goodrow; N Ulahannan; Charles Antzelevitch; José M Di Diego
Functionally distinct sodium channels in ventricular epicardial and endocardial cells contribute to a greater sensitivity of the epicardium to electrical depression.
American journal of physiology. Heart and circulatory physiology 2008;295(1):H154-62.
2008: Eyal Nof; Charles Antzelevitch
Risk stratification [corrected] of Brugada syndrome revisited.
The Israel Medical Association journal : IMAJ 2008;10(6):462-4.
2008: Gi-Byoung Nam; You-Ho Kim; Charles Antzelevitch
Augmentation of J waves and electrical storms in patients with early repolarization.
The New England journal of medicine 2008;358(19):2078-9.
2008: Charles Antzelevitch
Ranolazine: a new antiarrhythmic agent for patients with non-ST-segment elevation acute coronary syndromes?
Nature clinical practice. Cardiovascular medicine 2008;5(5):248-9.
2008: Chinmay Patel; Charles Antzelevitch
Pharmacological approach to the treatment of long and short QT syndromes.
Pharmacology & therapeutics 2008;118(1):138-51.
2008: Chinmay Patel; Charles Antzelevitch
Cellular basis for arrhythmogenesis in an experimental model of the SQT1 form of the short QT syndrome.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(4):585-90.
2008: Johnson Francis; Charles Antzelevitch
Atrial fibrillation and Brugada syndrome.
Journal of the American College of Cardiology 2008;51(12):1149-53.
2008: Alexander Burashnikov; José M Di Diego; Andrew C Zygmunt; Luiz Belardinelli; Charles Antzelevitch
Atrial-selective sodium channel block as a strategy for suppression of atrial fibrillation.
Annals of the New York Academy of Sciences 2008;1123():105-12.
2008: Serge Sicouri; Charles Antzelevitch
Sudden cardiac death secondary to antidepressant and antipsychotic drugs.
Expert opinion on drug safety 2008;7(2):181-94.
2008: Lasse Steen Ravn; Yoshiyasu Aizawa; Guido D Pollevick; Jacob Hofman-Bang; Jonathan M Cordeiro; Ulrik Dixen; Gorm Jensen; Yuesheng Wu; Elena Burashnikov; Stig Haunso; Alejandra Guerchicoff; Dan Hu; Jesper H Svendsen; Michael Christiansen; Charles Antzelevitch
Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(3):427-35.
2008: Jeffrey M Fish; Charles Antzelevitch
Cellular mechanism and arrhythmogenic potential of T-wave alternans in the Brugada syndrome.
Journal of cardiovascular electrophysiology 2008;19(3):301-8.
2008: Rainer Schimpf; Charles Antzelevitch; Dariush Haghi; Carla Giustetto; Alfredo Pizzuti; Fiorenzo Gaita; Christian Veltmann; Christian Wolpert; Martin Borggrefe
Electromechanical coupling in patients with the short QT syndrome: further insights into the mechanoelectrical hypothesis of the U wave.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(2):241-5.
2008: Lin Wu; Sridharan Rajamani; John C Shryock; Hong Li; Jeremy Ruskin; Charles Antzelevitch; Luiz Belardinelli
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
Cardiovascular research 2008;77(3):481-8.
2008: Charles Antzelevitch
Drug-induced spatial dispersion of repolarization.
Cardiology journal 2008;15(2):100-21.
2007: Jonathan M Cordeiro; Jane E Malone; José M Di Diego; Fabiana S Scornik; Gary L Aistrup; Charles Antzelevitch; J Andrew Wasserstrom
Cellular and subcellular alternans in the canine left ventricle.
American journal of physiology. Heart and circulatory physiology 2007;293(6):H3506-16.
2007: Sami Viskin; Charles Antzelevitch; Manlio F Márquez; Bernard Belhassen
Quinidine: a valuable medication joins the list of 'endangered species'.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2007;9(12):1105-6.
2007: Dan Hu; Sami Viskin; Antonio Oliva; Jonathan M Cordeiro; Alejandra Guerchicoff; Guido D Pollevick; Charles Antzelevitch
Genetic predisposition and cellular basis for ischemia-induced ST-segment changes and arrhythmias.
Journal of electrocardiology 2007;40(6 Suppl):S26-9.
2007: Aaron Glass; Serge Sicouri; Charles Antzelevitch
Development of a coronary-perfused interventricular septal preparation as a model for studying the role of the septum in arrhythmogenesis.
Journal of electrocardiology 2007;40(6 Suppl):S142-4.
2007: Charles Antzelevitch
Role of spatial dispersion of repolarization in inherited and acquired sudden cardiac death syndromes.
American journal of physiology. Heart and circulatory physiology 2007;293(4):H2024-38.
2007: Alexander Burashnikov; José M Di Diego; Andrew C Zygmunt; Luiz Belardinelli; Charles Antzelevitch
Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine.
Circulation 2007;116(13):1449-57.
2007: Charles Antzelevitch
Ionic, molecular, and cellular bases of QT-interval prolongation and torsade de pointes.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2007;9 Suppl 4():iv4-15.
2007: Yoshiyasu Aizawa; Kazuo Ueda; Fabiana S Scornik; Jonathan M Cordeiro; Yuesheng Wu; Mayurika Desai; Alejandra Guerchicoff; Yasutoshi Nagata; Yoshito Iesaka; Akinori Kimura; Masayasu Hiraoka; Charles Antzelevitch
A novel mutation in KCNQ1 associated with a potent dominant negative effect as the basis for the LQT1 form of the long QT syndrome.
Journal of cardiovascular electrophysiology 2007;18(9):972-7.
2007: Charles Antzelevitch; Serge Sicouri; José M Di Diego; Alexander Burashnikov; Sami Viskin; Wataru Shimizu; Gan-Xin Yan; Peter R Kowey; Li Zhang
Does Tpeak-Tend provide an index of transmural dispersion of repolarization?
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(8):1114-6; author reply 1116-9.
2007: Dan Hu; Sami Viskin; Antonio Oliva; Tabitha Carrier; Jonathan M Cordeiro; Hector Barajas-Martinez; Yuesheng Wu; Elena Burashnikov; Serge Sicouri; Ramon Brugada; Rafael Rosso; Alejandra Guerchicoff; Guido D Pollevick; Charles Antzelevitch
Novel mutation in the SCN5A gene associated with arrhythmic storm development during acute myocardial infarction.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(8):1072-80.
2007: Charles Antzelevitch
Heterogeneity and cardiac arrhythmias: an overview.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(7):964-72.
2007: Charles Antzelevitch
Genetic basis of Brugada syndrome.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(6):756-7.
2007: Serge Sicouri; Katherine W Timothy; Andrew C Zygmunt; Aaron Glass; Robert J Goodrow; Luiz Belardinelli; Charles Antzelevitch
Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(5):638-47.
2007: Charles Antzelevitch; Guido D Pollevick; Jonathan M Cordeiro; Oscar Casis; Michael C Sanguinetti; Yoshiyasu Aizawa; Alejandra Guerchicoff; Ryan Pfeiffer; Antonio Oliva; Bernd Wollnik; Philip Gelber; Elias P Bonaros; Elena Burashnikov; Yuesheng Wu; John D Sargent; Stefan Schickel; Ralf Oberheiden; Atul Bhatia; Li-Fern Hsu; Michel Haïssaguerre; Rainer Schimpf; Martin Borggrefe; Christian Wolpert
Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death.
Circulation 2007;115(4):442-9.
2006: Jonathan M Cordeiro; Hector Barajas-Martinez; Kui Hong; Elena Burashnikov; Ryan Pfeiffer; Anne-Marie Orsino; Yue Sheng Wu; Dan Hu; Josep Brugada; Pedro Brugada; Charles Antzelevitch; Robert Dumaine; Ramon Brugada
Compound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome.
Circulation 2006;114(19):2026-33.
2006: Charles Antzelevitch
Cellular basis for the repolarization waves of the ECG.
Annals of the New York Academy of Sciences 2006;1080():268-81.
2006: Charles Antzelevitch
Brugada syndrome.
Pacing and clinical electrophysiology : PACE 2006;29(10):1130-59.
2006: Kevin Vernooy; Serge Sicouri; Robert Dumaine; Kui Hong; Antonio Oliva; Elena Burashnikov; Carl Timmermans; Tammo Delhaas; Harry J G M Crijns; Charles Antzelevitch; Luz-Maria Rodriguez; Ramon Brugada
Genetic and biophysical basis for bupivacaine-induced ST segment elevation and VT/VF. Anesthesia unmasked Brugada syndrome.
Heart rhythm : the official journal of the Heart Rhythm Society 2006;3(9):1074-8.
2006: Tengxian Liu; Barry S Brown; Ying Wu; Charles Antzelevitch; Peter R Kowey; Gan-Xin Yan
Blinded validation of the isolated arterially perfused rabbit ventricular wedge in preclinical assessment of drug-induced proarrhythmias.
Heart rhythm : the official journal of the Heart Rhythm Society 2006;3(8):948-56.
2006: Fabiana S Scornik; Mayurika Desai; Ramon Brugada; Alejandra Guerchicoff; Guido D Pollevick; Charles Antzelevitch; Guillermo J Pérez
Functional expression of "cardiac-type" Nav1.5 sodium channel in canine intracardiac ganglia.
Heart rhythm : the official journal of the Heart Rhythm Society 2006;3(7):842-50.
2006: Jesús Castro Hevia; Charles Antzelevitch; Francisco Tornés Bárzaga; Margarita Dorantes Sánchez; Francisco Dorticós Balea; Roberto Zayas Molina; Miguel Angel Quiñones Pérez; Yanela Fayad Rodríguez
Tpeak-Tend and Tpeak-Tend dispersion as risk factors for ventricular tachycardia/ventricular fibrillation in patients with the Brugada syndrome.
Journal of the American College of Cardiology 2006;47(9):1828-34.
2006: Charles Antzelevitch; Luiz Belardinelli
The role of sodium channel current in modulating transmural dispersion of repolarization and arrhythmogenesis.
Journal of cardiovascular electrophysiology 2006;17 Suppl 1():S79-S85.
2006: Barry J Maron; Jeffrey A Towbin; Gaetano Thiene; Charles Antzelevitch; Domenico Corrado; Donna K Arnett; Arthur J Moss; Christine E Seidman; James B Young
Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention.
Circulation 2006;113(14):1807-16.
2006: Jeffrey M Fish; Daniel R Welchons; Young-Sup Kim; Suk-Ho Lee; Won-Kyung Ho; Charles Antzelevitch
Dimethyl lithospermate B, an extract of Danshen, suppresses arrhythmogenesis associated with the Brugada syndrome.
Circulation 2006;113(11):1393-400.
2006: Alexander Burashnikov; Charles Antzelevitch
Late-phase 3 EAD. A unique mechanism contributing to initiation of atrial fibrillation.
Pacing and clinical electrophysiology : PACE 2006;29(3):290-5.
2006: Masato Tsuboi; Charles Antzelevitch
Cellular basis for electrocardiographic and arrhythmic manifestations of Andersen-Tawil syndrome (LQT7).
Heart rhythm : the official journal of the Heart Rhythm Society 2006;3(3):328-35.
2006: Kevin Vernooy; Tammo Delhaas; Olaf L Cremer; José M Di Diego; Antonio Oliva; Carl Timmermans; Paul G A Volders; Frits W Prinzen; Harry J G M Crijns; Charles Antzelevitch; Cor Kalkman; Luz-Maria Rodriguez; Ramon Brugada
Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome.
Heart rhythm : the official journal of the Heart Rhythm Society 2006;3(2):131-7.
2006: Sami Viskin; Raphael Rosso; Ori Rogowski; Bernard Belhassen; Aviva Levitas; Abraham Wagshal; Amos Katz; Dana Fourey; David Zeltser; Antonio Oliva; Guido D Pollevick; Charles Antzelevitch; Uri Rozovski
Provocation of sudden heart rate oscillation with adenosine exposes abnormal QT responses in patients with long QT syndrome: a bedside test for diagnosing long QT syndrome.
European heart journal 2006;27(4):469-75.
2006: Charles Antzelevitch; Jeffrey M Fish
Therapy for the Brugada syndrome.
Handbook of experimental pharmacology 2006;(171):305-30.
2006: Charles Antzelevitch; Antonio Oliva
Amplification of spatial dispersion of repolarization underlies sudden cardiac death associated with catecholaminergic polymorphic VT, long QT, short QT and Brugada syndromes.
Journal of internal medicine 2006;259(1):48-58.
2005: Jeffrey M Fish; Josep Brugada; Charles Antzelevitch
Potential proarrhythmic effects of biventricular pacing.
Journal of the American College of Cardiology 2005;46(12):2340-7.
2005: Charles Antzelevitch
Role of transmural dispersion of repolarization in the genesis of drug-induced torsades de pointes.
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(2 Suppl):S9-15.
2005: Danny L Costantini; Eric P Arruda; Pooja Agarwal; Kyoung-Han Kim; Yonghong Zhu; Wei Zhu; Mélanie Lebel; Chi Wa Cheng; Chong Y Park; Stephanie A Pierce; Alejandra Guerchicoff; Guido D Pollevick; Toby Y Chan; golam kabir; Shuk Han Cheng; Mansoor Husain; Charles Antzelevitch; Deepak Srivastava; Gil J Gross; Chi-Chung Hui; Peter H Backx; Benoit G Bruneau
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient.
Cell 2005;123(2):347-58.
2005: Sami Viskin; Charles Antzelevitch
The cardiologists' worst nightmare sudden death from "benign" ventricular arrhythmias.
Journal of the American College of Cardiology 2005;46(7):1295-7.
2005: Martin Borggrefe; Christian Wolpert; Charles Antzelevitch; Christian Veltmann; Carla Giustetto; Fiorenzo Gaita; Rainer Schimpf
Short QT syndrome. Genotype-phenotype correlations.
Journal of electrocardiology 2005;38(4 Suppl):75-80.
2005: José M Di Diego; Jeffrey M Fish; Charles Antzelevitch
Brugada syndrome and ischemia-induced ST-segment elevation. Similarities and differences.
Journal of electrocardiology 2005;38(4 Suppl):14-7.
2005: Charles Antzelevitch
Cardiac repolarization. The long and short of it.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2005;7 Suppl 2():3-9.
2005: Charles Antzelevitch
In vivo human demonstration of phase 2 reentry.
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(8):804-6.
2005: Andrés Ricardo Pérez Riera; Charles Antzelevitch; Edgardo Schapacknik; Sergio J Dubner; Celso Ferreira
Is there an overlap between Brugada syndrome and arrhythmogenic right ventricular cardiomyopathy/dysplasia?
Journal of electrocardiology 2005;38(3):260-3.
2005: Charles Antzelevitch
Modulation of transmural repolarization.
Annals of the New York Academy of Sciences 2005;1047():314-23.
2005: Alexander Burashnikov; Charles Antzelevitch
Role of repolarization restitution in the development of coarse and fine atrial fibrillation in the isolated canine right atria.
Journal of cardiovascular electrophysiology 2005;16(6):639-45.
2005: Gi-Byoung Nam; Alexander Burashnikov; Charles Antzelevitch
Cellular mechanisms underlying the development of catecholaminergic ventricular tachycardia.
Circulation 2005;111(21):2727-33.
2005: Johnson Francis; Charles Antzelevitch
Brugada syndrome.
International journal of cardiology 2005;101(2):173-8.
2005: Charles Antzelevitch; Pedro Brugada; Martin Borggrefe; Josep Brugada; Ramon Brugada; Domenico Corrado; Ihor Gussak; Herve LeMarec; Koonlawee Nademanee; Andres Ricardo Perez Riera; Wataru Shimizu; Eric Schulze-Bahr; Hanno Tan; Arthur Wilde
Brugada syndrome: report of the second consensus conference.
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(4):429-40.
2005: Christian Wolpert; Constanze Echternach; Christian Veltmann; Charles Antzelevitch; George P Thomas; Susanne Spehl; Florian Streitner; Juergen Kuschyk; Rainer Schimpf; Karl K Haase; Martin Borggrefe
Intravenous drug challenge using flecainide and ajmaline in patients with Brugada syndrome.
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(3):254-60.
2005: Charles Antzelevitch; Pedro Brugada; Martin Borggrefe; Josep Brugada; Ramon Brugada; Domenico Corrado; Ihor Gussak; Herve LeMarec; Koonlawee Nademanee; Andres Ricardo Perez Riera; Wataru Shimizu; Eric Schulze-Bahr; Hanno Tan; Arthur Wilde
Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.
Circulation 2005;111(5):659-70.
2005: Wataru Shimizu; Takeshi Aiba; Charles Antzelevitch
Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. Long QT syndrome and Brugada syndrome.
Current pharmaceutical design 2005;11(12):1561-72.
2005: Christian Wolpert; Rainer Schimpf; Carla Giustetto; Charles Antzelevitch; Jonathan M Cordeiro; Robert Dumaine; Ramon Brugada; Kui Hong; Urs Bauersfeld; Fiorenzo Gaita; Martin Borggrefe
Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG.
Journal of cardiovascular electrophysiology 2005;16(1):54-8.
2005: Charles Antzelevitch; Pedro Brugada; Josep Brugada; Ramon Brugada
Brugada syndrome: from cell to bedside.
Current problems in cardiology 2005;30(1):9-54.
2004: Fabrice Extramiana; Charles Antzelevitch
Amplified transmural dispersion of repolarization as the basis for arrhythmogenesis in a canine ventricular-wedge model of short-QT syndrome.
Circulation 2004;110(24):3661-6.
2004: Kui Hong; Charles Antzelevitch; Pedro Brugada; Josep Brugada; Tohru Ohe; Ramon Brugada
Brugada syndrome: 12 years of progression.
Acta medica Okayama 2004;58(6):255-61.
2004: Kui Hong; Josep Brugada; Antonio Oliva; Antonio Berruezo-Sanchez; Domenico Potenza; Guido D Pollevick; Alejandra Guerchicoff; Kiyotaka Matsuo; Elena Burashnikov; Robert Dumaine; Jeffrey A Towbin; Vladislav Nesterenko; Pedro Brugada; Charles Antzelevitch; Ramon Brugada
Value of electrocardiographic parameters and ajmaline test in the diagnosis of Brugada syndrome caused by SCN5A mutations.
Circulation 2004;110(19):3023-7.
2004: Charles Antzelevitch; Luiz Belardinelli; Lin Wu; Heather Fraser; Andrew C Zygmunt; Alexander Burashnikov; José M Di Diego; Jeffrey M Fish; Jonathan M Cordeiro; Robert J Goodrow; Fabiana S Scornik; Guillermo Perez
Electrophysiologic properties and antiarrhythmic actions of a novel antianginal agent.
Journal of cardiovascular pharmacology and therapeutics 2004;9 Suppl 1():S65-83.
2004: Masahiko Kondo; Vladislav Nesterenko; Charles Antzelevitch
Cellular basis for the monophasic action potential. Which electrode is the recording electrode?
Cardiovascular research 2004;63(4):635-44.
2004: Charles Antzelevitch; Luiz Belardinelli; Andrew C Zygmunt; Alexander Burashnikov; José M Di Diego; Jeffrey M Fish; Jonathan M Cordeiro; George Thomas
Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties.
Circulation 2004;110(8):904-10.
2004: Jeffrey M Fish; Charles Antzelevitch
Link between hypothermia and the Brugada syndrome.
Journal of cardiovascular electrophysiology 2004;15(8):942-4.
2004: Lin Wu; John C Shryock; Yejia Song; Yuan Li; Charles Antzelevitch; Luiz Belardinelli
Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome.
The Journal of pharmacology and experimental therapeutics 2004;310(2):599-605.
2004: Jeffrey M Fish; Charles Antzelevitch
Role of sodium and calcium channel block in unmasking the Brugada syndrome.
Heart rhythm : the official journal of the Heart Rhythm Society 2004;1(2):210-7.
2004: Alexander Burashnikov; Sandeep Mannava; Charles Antzelevitch
Transmembrane action potential heterogeneity in the canine isolated arterially perfused right atrium: effect of IKr and IKur/Ito block.
American journal of physiology. Heart and circulatory physiology 2004;286(6):H2393-400.
2004: Jeffrey M Fish; José M Di Diego; Vladislav Nesterenko; Charles Antzelevitch
Epicardial activation of left ventricular wall prolongs QT interval and transmural dispersion of repolarization: implications for biventricular pacing.
Circulation 2004;109(17):2136-42.
2004: Fiorenzo Gaita; Carla Giustetto; Francesca Bianchi; Rainer Schimpf; Michel Haissaguerre; Leonardo Calò; Ramon Brugada; Charles Antzelevitch; Martin Borggrefe; Christian Wolpert
Short QT syndrome: pharmacological treatment.
Journal of the American College of Cardiology 2004;43(8):1494-9.
2004: Robert R Fenichel; Marek Malik; Charles Antzelevitch; Michael Sanguinetti; Dan Mark Roden; silvia priori; Jeremy N Ruskin; Raymond J Lipicky; Louis R Cantilena
Drug-induced torsades de pointes and implications for drug development.
Journal of cardiovascular electrophysiology 2004;15(4):475-95.
2004: Jonathan M Cordeiro; Lindsey Greene; Cory Heilmann; Daniel Antzelevitch; Charles Antzelevitch
Transmural heterogeneity of calcium activity and mechanical function in the canine left ventricle.
American journal of physiology. Heart and circulatory physiology 2004;286(4):H1471-9.
2004: Sami Viskin; David Zelster; Charles Antzelevitch
When u say "U Waves," what do u mean?
Pacing and clinical electrophysiology : PACE 2004;27(2):145-7.
2004: Ramon Brugada; Kui Hong; Robert Dumaine; Jonathan M Cordeiro; Fiorenzo Gaita; Martin Borggrefe; Teresa M Menendez; Josep Brugada; Guido D Pollevick; Christian Wolpert; Elena Burashnikov; Kiyotaka Matsuo; Yue Sheng Wu; Alejandra Guerchicoff; Francesca Bianchi; Carla Giustetto; Rainer Schimpf; Pedro Brugada; Charles Antzelevitch
Sudden death associated with short-QT syndrome linked to mutations in HERG.
Circulation 2004;109(1):30-5.
2004: Charles Antzelevitch; Johnson Francis
Congenital short QT syndrome.
Indian pacing and electrophysiology journal 2004;4(2):46-9.
2004: Charles Antzelevitch
Arrhythmogenic mechanisms of QT prolonging drugs: is QT prolongation really the problem?
Journal of electrocardiology 2004;37 Suppl():15-24.
2004: Charles Antzelevitch
Cellular basis and mechanism underlying normal and abnormal myocardial repolarization and arrhythmogenesis.
Annals of medicine 2004;36 Suppl 1():5-14.
2004: Kui Hong; Antonio Berruezo-Sanchez; Naravat Poungvarin; Antonio Oliva; Matteo Vatta; Josep Brugada; Pedro Brugada; Jeffrey A Towbin; Robert Dumaine; Carlos Piñero-Galvez; Charles Antzelevitch; Ramon Brugada
Phenotypic characterization of a large European family with Brugada syndrome displaying a sudden unexpected death syndrome mutation in SCN5A:.
Journal of cardiovascular electrophysiology 2004;15(1):64-9.
2004: Richard L Verrier; Charles Antzelevitch
Autonomic aspects of arrhythmogenesis: the enduring and the new.
Current opinion in cardiology 2004;19(1):2-11.
2003: Luiz Belardinelli; Charles Antzelevitch; Marc A Vos
Assessing predictors of drug-induced torsade de pointes.
Trends in pharmacological sciences 2003;24(12):619-25.
2003: Charles Antzelevitch
Molecular genetics of arrhythmias and cardiovascular conditions associated with arrhythmias.
Journal of cardiovascular electrophysiology 2003;14(11):1259-72.
2003: Charles Antzelevitch
Molecular genetics of arrhythmias and cardiovascular conditions associated with arrhythmias.
Pacing and clinical electrophysiology : PACE 2003;26(11):2194-208.
2003: José M Di Diego; Luiz Belardinelli; Charles Antzelevitch
Cisapride-induced transmural dispersion of repolarization and torsade de pointes in the canine left ventricular wedge preparation during epicardial stimulation.
Circulation 2003;108(8):1027-33.
2003: Charles Antzelevitch
Brugada syndrome: clinical, genetic, molecular, cellular and ionic aspects.
Expert review of cardiovascular therapy 2003;1(2):177-85.
2003: Charles Antzelevitch
Androgens and male predominance of the Brugada syndrome phenotype.
Pacing and clinical electrophysiology : PACE 2003;26(7 Pt 1):1429-31.
2003: Charles Antzelevitch; Pedro Brugada; Josep Brugada; Ramon Brugada; Jeffrey A Towbin; Koonlawee Nademanee
Brugada syndrome: 1992-2002: a historical perspective.
Journal of the American College of Cardiology 2003;41(10):1665-71.
2003: Alexander Burashnikov; Charles Antzelevitch
Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity.
Circulation 2003;107(18):2355-60.
2003: Victor A Medina-Ravell; Ramarao S Lankipalli; Gan-Xin Yan; Charles Antzelevitch; Napoleon A Medina-Malpica; Otto A Medina-Malpica; Christopher Droogan; Peter R Kowey
Effect of epicardial or biventricular pacing to prolong QT interval and increase transmural dispersion of repolarization: does resynchronization therapy pose a risk for patients predisposed to long QT or torsade de pointes?
Circulation 2003;107(5):740-6.
2003: Johnson Francis; Charles Antzelevitch
Brugada-like electrocardiographic pattern.
Indian pacing and electrophysiology journal 2003;3(3):91-2.
2003: Jeffrey M Fish; Charles Antzelevitch
Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypes.
Journal of electrocardiology 2003;36 Suppl():173-9.
2003: José M Di Diego; Charles Antzelevitch
Cellular basis for ST-segment changes observed during ischemia.
Journal of electrocardiology 2003;36 Suppl():1-5.
2003: Charles Antzelevitch; Nabil El-Sherif; David Rosenbaum; Marc Vos
Cellular mechanisms underlying the long QT syndrome.
Journal of cardiovascular electrophysiology 2003;14(1):114; author reply 114-5.
2003: George P Thomas; Uwe Gerlach; Charles Antzelevitch
HMR 1556, a potent and selective blocker of slowly activating delayed rectifier potassium current.
Journal of cardiovascular pharmacology 2003;41(1):140-7.
2002: Charles Antzelevitch; Pedro Brugada; Josep Brugada; Ramon Brugada; Wataru Shimizu; Ihor Gussak; Andres Ricardo Perez Riera
Brugada syndrome: a decade of progress.
Circulation research 2002;91(12):1114-8.
2002: Arthur A M Wilde; Charles Antzelevitch; Martin Borggrefe; Josep Brugada; Ramon Brugada; Pedro Brugada; Domenico Corrado; Richard N W Hauer; Robert Kass; Koonlawee Nademanee; silvia priori; Jeffrey A Towbin
Proposed diagnostic criteria for the Brugada syndrome: consensus report.
Circulation 2002;106(19):2514-9.
2002: Bernard Belhassen; Sami Viskin; Charles Antzelevitch
The Brugada syndrome: is an implantable cardioverter defibrillator the only therapeutic option?
Pacing and clinical electrophysiology : PACE 2002;25(11):1634-40.
2002: Charles Antzelevitch; Ramon Brugada
Fever and Brugada syndrome.
Pacing and clinical electrophysiology : PACE 2002;25(11):1537-9.
2002: Arthur A M Wilde; Charles Antzelevitch; Martin Borggrefe; Josep Brugada; Ramon Brugada; Pedro Brugada; Domenico Corrado; Richard N W Hauer; Robert Kass; Koonlawee Nademanee; silvia priori; J A Towbin
Proposed diagnostic criteria for the Brugada syndrome.
European heart journal 2002;23(21):1648-54.
2002: José M Di Diego; Jonathan M Cordeiro; Robert J Goodrow; Jeffrey M Fish; Andrew C Zygmunt; Guillermo J Pérez; Fabiana S Scornik; Charles Antzelevitch
Ionic and cellular basis for the predominance of the Brugada syndrome phenotype in males.
Circulation 2002;106(15):2004-11.
2002: Charles Antzelevitch
Late potentials and the Brugada syndrome.
Journal of the American College of Cardiology 2002;39(12):1996-9.
2002: Matteo Vatta; Robert Dumaine; Charles Antzelevitch; Ramon Brugada; Hua Li; Neil E Bowles; Koonlawee Nademanee; Josep Brugada; Pedro Brugada; Jeffrey A Towbin
Novel mutations in domain I of SCN5A cause Brugada syndrome.
Molecular genetics and metabolism 2002;75(4):317-24.
2002: Fadi G Akar; Gan-Xin Yan; Charles Antzelevitch; David S Rosenbaum
Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome.
Circulation 2002;105(10):1247-53.
2002: Ihor Gussak; Pedro Brugada; Josep Brugada; Charles Antzelevitch; Mary D Osbakken; Preben Bjerregaard
ECG phenomenon of idiopathic and paradoxical short QT intervals.
Cardiac electrophysiology review 2002;6(1-2):49-53.
2002: Alexander Burashnikov; Charles Antzelevitch
Prominent I(Ks) in epicardium and endocardium contributes to development of transmural dispersion of repolarization but protects against development of early afterdepolarizations.
Journal of cardiovascular electrophysiology 2002;13(2):172-7.
2002: Matteo Vatta; Robert Dumaine; George Varghese; Todd A Richard; Wataru Shimizu; Naohiko Aihara; Koonlawee Nademanee; Ramon Brugada; Josep Brugada; Gavivann Veerakul; Hua Li; Neil E Bowles; Pedro Brugada; Charles Antzelevitch; Jeffrey A Towbin
Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome.
Human molecular genetics 2002;11(3):337-45.
2002: Charles Antzelevitch; Wataru Shimizu
Cellular mechanisms underlying the long QT syndrome.
Current opinion in cardiology 2002;17(1):43-51.
2002: Robert Dumaine; Charles Antzelevitch
Molecular mechanisms underlying the long QT syndrome.
Current opinion in cardiology 2002;17(1):36-42.
2002: Gerald V Naccarelli; Charles Antzelevitch; Deborah L Wolbrette; Jerry C Luck
The Brugada syndrome.
Current opinion in cardiology 2002;17(1):19-23.
2002: Josep Brugada; Ramon Brugada; Charles Antzelevitch; Jeffrey Towbin; Koonlawee Nademanee; Pedro Brugada
Long-term follow-up of individuals with the electrocardiographic pattern of right bundle-branch block and ST-segment elevation in precordial leads V1 to V3.
Circulation 2002;105(1):73-8.
2001: T Emori; Charles Antzelevitch
Cellular basis for complex T waves and arrhythmic activity following combined I(Kr) and I(Ks) block.
Journal of cardiovascular electrophysiology 2001;12(12):1369-78.
2001: Charles Antzelevitch; J Fish
Electrical heterogeneity within the ventricular wall.
Basic research in cardiology 2001;96(6):517-27.
2001: Andrew C Zygmunt; G T Eddlestone; GP Thomas; Vladislav Nesterenko; Charles Antzelevitch
Larger late sodium conductance in M cells contributes to electrical heterogeneity in canine ventricle.
American journal of physiology. Heart and circulatory physiology 2001;281(2):H689-97.
2001: Charles Antzelevitch
Molecular basis for the transmural distribution of the transient outward current.
The Journal of physiology 2001;533(Pt 1):1.
2001: Z Q Sun; GP Thomas; Charles Antzelevitch
Chromanol 293B inhibits slowly activating delayed rectifier and transient outward currents in canine left ventricular myocytes.
Journal of cardiovascular electrophysiology 2001;12(4):472-8.
2001: Charles Antzelevitch
The Brugada syndrome: ionic basis and arrhythmia mechanisms.
Journal of cardiovascular electrophysiology 2001;12(2):268-72.
2001: Charles Antzelevitch
Molecular biology and cellular mechanisms of Brugada and long QT syndromes in infants and young children.
Journal of electrocardiology 2001;34 Suppl():177-81.
2001: Charles Antzelevitch
Basic mechanisms of reentrant arrhythmias.
Current opinion in cardiology 2001;16(1):1-7.
2000: Wataru Shimizu; Charles Antzelevitch; Kazuhiro Suyama; Takashi Kurita; Atsushi Taguchi; Naohiko Aihara; H Takaki; K Sunagawa; Shiro Kamakura
Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome.
Journal of cardiovascular electrophysiology 2000;11(12):1320-9.
2000: Wataru Shimizu; Charles Antzelevitch
Effects of a K(+) channel opener to reduce transmural dispersion of repolarization and prevent torsade de pointes in LQT1, LQT2, and LQT3 models of the long-QT syndrome.
Circulation 2000;102(6):706-12.
2000: Peter J Schwartz; silvia priori; Robert Dumaine; Carlo Napolitano; Charles Antzelevitch; Marco Stramba-Badiale; T A Richard; M R Berti; Raffaella Bloise
A molecular link between the sudden infant death syndrome and the long-QT syndrome.
The New England journal of medicine 2000;343(4):262-7.
2000: Andrew C Zygmunt; Robert J Goodrow; Charles Antzelevitch
I(NaCa) contributes to electrical heterogeneity within the canine ventricle.
American journal of physiology. Heart and circulatory physiology 2000;278(5):H1671-8.
2000: Alexander Burashnikov; Charles Antzelevitch
Block of I(Ks) does not induce early afterdepolarization activity but promotes beta-adrenergic agonist-induced delayed afterdepolarization activity.
Journal of cardiovascular electrophysiology 2000;11(4):458-65.
2000: Jacques Weissenburger; Vladislav Nesterenko; Charles Antzelevitch
Transmural heterogeneity of ventricular repolarization under baseline and long QT conditions in the canine heart in vivo: torsades de pointes develops with halothane but not pentobarbital anesthesia.
Journal of cardiovascular electrophysiology 2000;11(3):290-304.
2000: Wataru Shimizu; Charles Antzelevitch
Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome.
Journal of the American College of Cardiology 2000;35(3):778-86.
2000: Ramon Brugada; Josep Brugada; Charles Antzelevitch; Glenn E Kirsch; D Potenza; Jeffrey A Towbin; Pedro Brugada
Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts.
Circulation 2000;101(5):510-5.
2000: Charles Antzelevitch; Gan-Xin Yan
Cellular and ionic mechanisms responsible for the Brugada syndrome.
Journal of electrocardiology 2000;33 Suppl():33-9.
1999: Robert Dumaine; J A Towbin; Pedro Brugada; Matteo Vatta; D V Nesterenko; V V Nesterenko; Josep Brugada; Ramon Brugada; Charles Antzelevitch
Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent.
Circulation research 1999;85(9):803-9.
1999: Gan-Xin Yan; Charles Antzelevitch
Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation.
Circulation 1999;100(15):1660-6.
1999: Alexander Burashnikov; Charles Antzelevitch
Differences in the electrophysiologic response of four canine ventricular cell types to alpha 1-adrenergic agonists.
Cardiovascular research 1999;43(4):901-8.
1999: Charles Antzelevitch; Wataru Shimizu; Gan-Xin Yan; Serge Sicouri; Jacques Weissenburger; Vladislav Nesterenko; Alexander Burashnikov; José M Di Diego; J Saffitz; GP Thomas
The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart.
Journal of cardiovascular electrophysiology 1999;10(8):1124-52.
1999: Charles Antzelevitch
Ion channels and ventricular arrhythmias: cellular and ionic mechanisms underlying the Brugada syndrome.
Current opinion in cardiology 1999;14(3):274-9.
1999: Wataru Shimizu; Charles Antzelevitch
Cellular and ionic basis for T-wave alternans under long-QT conditions.
Circulation 1999;99(11):1499-507.
1999: Wataru Shimizu; B McMahon; Charles Antzelevitch
Sodium pentobarbital reduces transmural dispersion of repolarization and prevents torsades de Pointes in models of acquired and congenital long QT syndrome.
Journal of cardiovascular electrophysiology 1999;10(2):154-64.
1999: Charles Antzelevitch; Gan-Xin Yan; Wataru Shimizu
Transmural dispersion of repolarization and arrhythmogenicity: the Brugada syndrome versus the long QT syndrome.
Journal of electrocardiology 1999;32 Suppl():158-65.
1998: Wataru Shimizu; Charles Antzelevitch
Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: effects of beta-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes.
Circulation 1998;98(21):2314-22.
1998: Gan-Xin Yan; Charles Antzelevitch
Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome.
Circulation 1998;98(18):1928-36.
1998: Gan-Xin Yan; Wataru Shimizu; Charles Antzelevitch
Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations.
Circulation 1998;98(18):1921-7.
1998: Alexander Burashnikov; Charles Antzelevitch
Acceleration-induced action potential prolongation and early afterdepolarizations.
Journal of cardiovascular electrophysiology 1998;9(9):934-48.
1998: Qiuyun Chen; Glenn E Kirsch; Dianzheng Zhang; Ramon Brugada; Josep Brugada; Pedro Brugada; D Potenza; A Moya; M Borggrefe; G Breithardt; R Ortiz-Lopez; Z Wang; Charles Antzelevitch; R E O'Brien; E Schulze-Bahr; M T Keating; Jeffrey A Towbin; Qing Wang
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation.
Nature 1998;392(6673):293-6.
1998: Charles Antzelevitch; Wataru Shimizu; Gan-Xin Yan; Serge Sicouri
Cellular basis for QT dispersion.
Journal of electrocardiology 1998;30 Suppl():168-75.
1997: Serge Sicouri; D Antzelevitch; C Heilmann; Charles Antzelevitch
Effects of sodium channel block with mexiletine to reverse action potential prolongation in in vitro models of the long term QT syndrome.
Journal of cardiovascular electrophysiology 1997;8(11):1280-90.
1997: Serge Sicouri; Sandra Moro; S Litovsky; Marcelo V Elizari; Charles Antzelevitch
Chronic amiodarone reduces transmural dispersion of repolarization in the canine heart.
Journal of cardiovascular electrophysiology 1997;8(11):1269-79.
1997: Wataru Shimizu; Charles Antzelevitch
Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade des pointes in LQT2 and LQT3 models of the long-QT syndrome.
Circulation 1997;96(6):2038-47.
1997: Andrew C Zygmunt; Robert J Goodrow; Charles Antzelevitch
Sodium effects on 4-aminopyridine-sensitive transient outward current in canine ventricular cells.
The American journal of physiology 1997;272(1 Pt 2):H1-11.
1996: Charles Antzelevitch; Z Q Sun; Z Q Zhang; Gan-Xin Yan
Cellular and ionic mechanisms underlying erythromycin-induced long QT intervals and torsade de pointes.
Journal of the American College of Cardiology 1996;28(7):1836-48.
1996: A Lukas; Charles Antzelevitch
Phase 2 reentry as a mechanism of initiation of circus movement reentry in canine epicardium exposed to simulated ischemia.
Cardiovascular research 1996;32(3):593-603.
1996: Jose Di Diego; Z Q Sun; Charles Antzelevitch
I(to) and action potential notch are smaller in left vs. right canine ventricular epicardium.
The American journal of physiology 1996;271(2 Pt 2):H548-61.
1996: Serge Sicouri; M Quist; Charles Antzelevitch
Evidence for the presence of M cells in the guinea pig ventricle.
Journal of cardiovascular electrophysiology 1996;7(6):503-11.
1996: Gan-Xin Yan; Charles Antzelevitch
Cellular basis for the electrocardiographic J wave.
Circulation 1996;93(2):372-9.
1995: Serge Sicouri; Charles Antzelevitch
Electrophysiologic characteristics of M cells in the canine left ventricular free wall.
Journal of cardiovascular electrophysiology 1995;6(8):591-603.
1995: D W Liu; Charles Antzelevitch
Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes. A weaker IKs contributes to the longer action potential of the M cell.
Circulation research 1995;76(3):351-65.
1995: Charles Antzelevitch; V V Nesterenko; Gan-Xin Yan
Role of M cells in acquired long QT syndrome, U waves, and torsade de pointes.
Journal of electrocardiology 1995;28 Suppl():131-8.
1994: Serge Sicouri; J Fish; Charles Antzelevitch
Distribution of M cells in the canine ventricle.
Journal of cardiovascular electrophysiology 1994;5(10):824-37.
1994: Jose Di Diego; Charles Antzelevitch
High [Ca2+]o-induced electrical heterogeneity and extrasystolic activity in isolated canine ventricular epicardium. Phase 2 reentry.
Circulation 1994;89(4):1839-50.
1994: Charles Antzelevitch; Serge Sicouri
Clinical relevance of cardiac arrhythmias generated by afterdepolarizations. Role of M cells in the generation of U waves, triggered activity and torsade de pointes.
Journal of the American College of Cardiology 1994;23(1):259-77.
1993: A Lukas; Charles Antzelevitch
Differences in the electrophysiological response of canine ventricular epicardium and endocardium to ischemia. Role of the transient outward current.
Circulation 1993;88(6):2903-15.
1993: Jose Di Diego; Charles Antzelevitch
Pinacidil-induced electrical heterogeneity and extrasystolic activity in canine ventricular tissues. Does activation of ATP-regulated potassium current promote phase 2 reentry?
Circulation 1993;88(3):1177-89.
1993: D W Liu; Gary Gintant; Charles Antzelevitch
Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle.
Circulation research 1993;72(3):671-87.
1993: S C Krishnan; Charles Antzelevitch
Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry?
Circulation 1993;87(2):562-72.
1993: Serge Sicouri; Charles Antzelevitch
Drug-induced afterdepolarizations and triggered activity occur in a discrete subpopulation of ventricular muscle cells (M cells) in the canine heart: quinidine and digitalis.
Journal of cardiovascular electrophysiology 1993;4(1):48-58.
1992: Charles Antzelevitch; Jose Di Diego
Role of K+ channel activators in cardiac electrophysiology and arrhythmias.
Circulation 1992;85(4):1627-9.
1991: Charles Antzelevitch; Serge Sicouri; S H Litovsky; A Lukas; S C Krishnan; Jose Di Diego; Gary Gintant; D W Liu
Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells.
Circulation research 1991;69(6):1427-49.
1991: Serge Sicouri; Charles Antzelevitch
Afterdepolarizations and triggered activity develop in a select population of cells (M cells) in canine ventricular myocardium: the effects of acetylstrophanthidin and Bay K 8644.
Pacing and clinical electrophysiology : PACE 1991;14(11 Pt 2):1714-20.
1991: S C Krishnan; Charles Antzelevitch
Sodium channel block produces opposite electrophysiological effects in canine ventricular epicardium and endocardium.
Circulation research 1991;69(2):277-91.
1991: Serge Sicouri; Charles Antzelevitch
A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle. The M cell.
Circulation research 1991;68(6):1729-41.
1990: S H Litovsky; Charles Antzelevitch
Differences in the electrophysiological response of canine ventricular subendocardium and subepicardium to acetylcholine and isoproterenol. A direct effect of acetylcholine in ventricular myocardium.
Circulation research 1990;67(3):615-27.
1989: S H Litovsky; Charles Antzelevitch
Rate dependence of action potential duration and refractoriness in canine ventricular endocardium differs from that of epicardium: role of the transient outward current.
Journal of the American College of Cardiology 1989;14(4):1053-66.
1989: A Lukas; Charles Antzelevitch
Reflected reentry, delayed conduction, and electrotonic inhibition in segmentally depressed atrial tissues.
Canadian journal of physiology and pharmacology 1989;67(7):757-64.
1989: J M Davidenko; L Cohen; Robert J Goodrow; Charles Antzelevitch
Quinidine-induced action potential prolongation, early afterdepolarizations, and triggered activity in canine Purkinje fibers. Effects of stimulation rate, potassium, and magnesium.
Circulation 1989;79(3):674-86.
1988: S H Litovsky; Charles Antzelevitch
Transient outward current prominent in canine ventricular epicardium but not endocardium.
Circulation research 1988;62(1):116-26.
1986: J M Davidenko; Charles Antzelevitch
Electrophysiological mechanisms underlying rate-dependent changes of refractoriness in normal and segmentally depressed canine Purkinje fibers. The characteristics of post-repolarization refractoriness.
Circulation research 1986;58(2):257-68.
1984: J M Davidenko; Charles Antzelevitch
The effects of milrinone on conduction, reflection, and automaticity in canine Purkinje fibers.
Circulation 1984;69(5):1026-35.