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Hiroshi Fukamachi

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Shu Shimada; Hiroshi Tanaka; Yoshimitsu Akiyama; Yoshinobu Eishi; Hiroshi Fukamachi; Jos Jonkers; Ayako Mimata; Kaoru Mogushi; Masaki Sekine; Yasuhito Yuasa
Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer.
Ayako Mimata; Hiroshi Fukamachi; Yoshinobu Eishi; Yasuhito Yuasa
Loss of E-cadherin in mouse gastric epithelial cells induces signet ring-like cells, a possible precursor lesion of diffuse gastric cancer.
Rie Wada; Yoshimitsu Akiyama; Yutaka Hashimoto; Hiroshi Fukamachi; Yasuhito Yuasa
miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer.

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All Publications

2012: Shu Shimada; Hiroshi Tanaka; Yoshimitsu Akiyama; Yoshinobu Eishi; Hiroshi Fukamachi; Jos Jonkers; Ayako Mimata; Kaoru Mogushi; Masaki Sekine; Yasuhito Yuasa
Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer.
Gut 2012;61(3):344-53.
2011: Ayako Mimata; Hiroshi Fukamachi; Yoshinobu Eishi; Yasuhito Yuasa
Loss of E-cadherin in mouse gastric epithelial cells induces signet ring-like cells, a possible precursor lesion of diffuse gastric cancer.
Cancer science 2011;102(5):942-50.
2010: Rie Wada; Yoshimitsu Akiyama; Yutaka Hashimoto; Hiroshi Fukamachi; Yasuhito Yuasa
miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer.
International journal of cancer. Journal international du cancer 2010;127(5):1106-14.
2008: Hiroshi Fukamachi; Ayako Mimata; Issei Tanaka; Kosei Ito; Yoshiaki Ito; Yasuhito Yuasa
In vitro differentiation of Runx3-/- p53-/- gastric epithelial cells into intestinal type cells.
Cancer science 2008;99(4):671-6.
2008: Shun-Hua Jin; Yoshimitsu Akiyama; Hiroshi Fukamachi; Kazuyoshi Yanagihara; Takumi Akashi; Yasuhito Yuasa
IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells.
International journal of cancer. Journal international du cancer 2008;122(5):1040-6.
2007: Noriko Makita; Junichiro Sato; Philippe Rondard; Hiroshi Fukamachi; Yasuhito Yuasa; Micheala A Aldred; Makiko Hashimoto; Toshiro Fujita; Taroh Iiri
Human G(salpha) mutant causes pseudohypoparathyroidism type Ia/neonatal diarrhea, a potential cell-specific role of the palmitoylation cycle.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(44):17424-9.
2007: Kaori Taniwaki; Hiroshi Fukamachi; Kiyoshi Komori; Yohei Ohtake; Takahiro Nonaka; Takeharu Sakamoto; Takayuki Shiomi; Yasunori Okada; Takeshi Itoh; Shigeyoshi Itohara; Motoharu Seiki; Ikuo Yana
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice.
Cancer research 2007;67(9):4311-9.
2007: Yasuyo Tani; Yoshimitsu Akiyama; Hiroshi Fukamachi; Kazuyoshi Yanagihara; Yasuhito Yuasa
Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.
Journal of cancer research and clinical oncology 2007;133(4):263-9.
2006: Masumi Takano-Maruyama; Koji Hase; Hiroshi Fukamachi; Yasutaka Kato; Haruhiko Koseki; Hiroshi Ohno
Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(1):G163-70.
2006: Hiroshi Fukamachi
Runx3 controls growth and differentiation of gastric epithelial cells in mammals.
Development, growth & differentiation 2006;48(1):1-13.
2005: Hiroshi Fukamachi; Takanori Narita; Naoya Yahagi; Hiroyuki Takeda; Masao Ichinose
Endothelin-3 controls growth of colonic epithelial cells by mediating epithelial-mesenchymal interaction.
Development, growth & differentiation 2005;47(8):573-80.
2004: Hiroshi Fukamachi; Kosei Ito; Yoshiaki Ito
Runx3-/- gastric epithelial cells differentiate into intestinal type cells.
Biochemical and biophysical research communications 2004;321(1):58-64.
2004: Yasutaka Kato; Hiroshi Fukamachi; Masumi Takano-Maruyama; Tomohiko Aoe; Yasuaki Murahashi; Syunji Horie; Yasuo Suzuki; Yasushi Saito; Haruhiko Koseki; Hiroshi Ohno
Reduction of SNAP25 in acid secretion defect of Foxl1-/- gastric parietal cells.
Biochemical and biophysical research communications 2004;320(3):766-72.
2004: Hiroshi Fukamachi; Kosei Ito
Growth regulation of gastric epithelial cells by Runx3.
Oncogene 2004;23(24):4330-5.
2003: Masatake Kai; Chikara Kaito; Hiroshi Fukamachi; Takayasu Higo; Eiji Takayama; Hiroshi Hara; Yoshikazu Ohya; Kazuei Igarashi; Koichiro Shiokawa
Overexpression of S-adenosylmethionine decarboxylase (SAMDC) in Xenopus embryos activates maternal program of apoptosis as a "fail-safe" mechanism of early embryogenesis.
Cell research 2003;13(3):147-58.
2001: Chikara Kaito; Masatake Kai; Takayasu Higo; Eiji Takayama; Hiroshi Fukamachi; Kazuhisa Sekimizu; Koichiro Shiokawa
Activation of the maternally preset program of apoptosis by microinjection of 5-aza-2'-deoxycytidine and 5-methyl-2'-deoxycytidine-5'-triphosphate in Xenopus laevis embryos.
Development, growth & differentiation 2001;43(4):383-90.
2001: Hiroshi Fukamachi; K Fukuda; M Suzuki; Tsuyoshi Furumoto; Masao Ichinose; S Shimizu; S Tsuchiya; S Horie; Yasuo Suzuki; Yasushi Saito; K Watanabe; M Taniguchi; Haruhiko Koseki
Mesenchymal transcription factor Fkh6 is essential for the development and differentiation of parietal cells.
Biochemical and biophysical research communications 2001;280(4):1069-76.
2000: Masatake Kai; Takayasu Higo; J Yokoska; Chikara Kaito; Eri Kajita; Hiroshi Fukamachi; Eiji Takayama; Kazuei Igarashi; Koichiro Shiokawa
Overexpression of S-adenosylmethionine decarboxylase (SAMDC) activates the maternal program of apoptosis shortly after MBT in Xenopus embryos.
The International journal of developmental biology 2000;44(5):507-10.
2000: H Hara; S Uchida; H Yoshimura; M Aoki; Y Toyoda; Y Sakai; S Morimoto; Hiroshi Fukamachi; Koichiro Shiokawa; K Hanada
Isolation and characterization of a novel liver-specific gene, hepassocin, upregulated during liver regeneration.
Biochimica et biophysica acta 2000;1492(1):31-44.
2000: Koichiro Shiokawa; Masatake Kai; Takayasu Higo; Chikara Kaito; J Yokoska; Yukuto Yasuhiko; Eri Kajita; M Nagano; Y Yamada; Mikihito Shibata; T Muto; Jun Shinga; Hiroshi Hara; Eiji Takayama; Hiroshi Fukamachi; Yoshio Yaoita; Kazuei Igarashi
Maternal program of apoptosis activated shortly after midblastula transition by overexpression of S-adenosylmethionine decarboxylase in Xenopus early embryos.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2000;126(2):149-55.
1999: Koichiro Shiokawa; Masatake Kai; Takayasu Higo; Hiroshi Fukamachi; Eiji Takayama
[Transcription in Xenopus early embryos and apoptotic program preset in the fertilized egg].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(1):32-41.
1998: Y Matsubara; Masao Ichinose; Naoya Yahagi; S Tsukada; Mikio Oka; Kazumasa Miki; Satoshi Kimura; Masao Omata; Koichiro Shiokawa; N Kitamura; Y Kaneko; Hiroshi Fukamachi
Hepatocyte growth factor activator: a possible regulator of morphogenesis during fetal development of the rat gastrointestinal tract.
Biochemical and biophysical research communications 1998;253(2):477-84.
1998: Shinya Bekku; Hidetaka Mochizuki; Eiji Takayama; N Shinomiya; Hiroshi Fukamachi; M Ichinose; Takushi Tadakuma; T Yamamoto
Carbonic anhydrase I and II as a differentiation marker of human and rat colonic enterocytes.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1998;198(4):175-85.
1998: M Kudo; Eiji Takayama; K Tashiro; Hiroshi Fukamachi; T Nakata; Takushi Tadakuma; Ken Kitajima; Y Inoue; Koichiro Shiokawa
Cloning and expression of an alpha-2,8-polysialyltransferase (STX) from Xenopus laevis.
Glycobiology 1998;8(8):771-7.
1998: S Tsukada; Masao Ichinose; Naoya Yahagi; Y Matsubara; S Yonezawa; Koichiro Shiokawa; Chie Furihata; Kazumasa Miki; Hiroshi Fukamachi
Induction of precocious pepsinogen synthesis by glucocorticoids in fetal rat gastric epithelium in organ culture: importance of mesenchyme for epithelial differentiation.
Differentiation; research in biological diversity 1998;62(5):239-47.
1997: T Suzuki; M Ichinose; Y Matsubara; Naoya Yahagi; K Kurokawa; Hiroshi Fukamachi; K Miki
Cowden's disease with a defined genetic alteration--chromosomal duplication at 15q11-q13.
Journal of gastroenterology 1997;32(5):696-9.
1997: Masao Ichinose; S Tsukada; Y Fujimitsu; Masae Tatematsu; Y Matsubara; Naoya Yahagi; Mikio Oka; Takahiro Suzuki; Yuko Shimizu; S Yonezawa; Takashi Kageyama; Kazumasa Miki; Hiroshi Fukamachi
Proliferation, differentiation and morphogenesis of fetal rat glandular stomach transplanted under the kidney capsule of syngeneic hosts.
Development, growth & differentiation 1997;39(5):635-42.
1997: Masao Ichinose; Naoya Yahagi; Y Matsubara; S Tsukada; Mikio Oka; Yuko Shimizu; S Yonezawa; Takashi Kageyama; Kazumasa Miki; Hiroshi Fukamachi
Substratum-dependent and region-specific control of attachment and proliferation of gastrointestinal epithelial cells in primary serum-free culture.
Biochemical and biophysical research communications 1997;230(3):537-41.
1996: Y Matsubara; M Ichinose; Masae Tatematsu; Masao Ichinose; Mikio Oka; Naoya Yahagi; Kiyoshi Kurokawa; T Kageyama; Kazumasa Miki; Hiroshi Fukamachi
Stage-specific elevated expression of the genes for hepatocyte growth factor, keratinocyte growth factor, and their receptors during the morphogenesis and differentiation of rat stomach mucosa.
Biochemical and biophysical research communications 1996;222(3):669-77.
1996: Naoya Yahagi; Masao Ichinose; M Matsushima; Y Matsubara; Kazumasa Miki; Kiyoshi Kurokawa; Hiroshi Fukamachi; Kei Tashiro; Koichiro Shiokawa; T Kageyama; T Takahashi; H Inoue; K Takahashi
Complementary DNA cloning and sequencing of rat enteropeptidase and tissue distribution of its mRNA.
Biochemical and biophysical research communications 1996;219(3):806-12.
1995: N Kakei; Masao Ichinose; Masae Tatematsu; M Shimizu; S Ishihama; Naoya Yahagi; M Matsushima; Hiroshi Fukamachi; Kazumasa Miki; Kiyoshi Kurokawa
Effect of CCK-B/gastrin receptor antagonist on pepsinogen-producing cells during omeprazole treatment.
Biochemical and biophysical research communications 1995;210(2):400-8.
1995: Hiroshi Fukamachi; Masao Ichinose; S Ishihama; S Tsukada; Chie Furihata; S Yonezawa; Kazumasa Miki
Cathepsin E is expressed in fetal rat glandular stomach epithelial cells in primary culture in the absence of mesenchymes.
Advances in experimental medicine and biology 1995;362():357-61.
1995: S Tsukada; Masao Ichinose; Kazumasa Miki; N Kakei; M Matsushima; Naoya Yahagi; S Ishihama; Y Shimizu; M Kido; Hiroshi Fukamachi
Tissue- and cell-specific control of guinea pig cathepsin E gene expression.
Advances in experimental medicine and biology 1995;362():349-55.
1995: Masao Ichinose; S Tsukada; Kazumasa Miki; N Kakei; M Matsushima; Naoya Yahagi; S Ishihama; Y Shimizu; Kiyoshi Kurokawa; Hiroshi Fukamachi
Effects of hydrocortisone on the pepsinogen-producing cells in rat stomach mucosa.
Advances in experimental medicine and biology 1995;362():107-13.
1994: Hiroshi Fukamachi; Masao Ichinose; S Tsukada; N Kakei; T Suzuki; K Miki; K Kurokawa; T Masui
Hepatocyte growth factor region specifically stimulates gastro-intestinal epithelial growth in primary culture.
Biochemical and biophysical research communications 1994;205(2):1445-51.
1994: Hiroshi Fukamachi; Masao Ichinose; S Ishihama; S Tsukada; Sadao Yasugi; Koichiro Shiokawa; Chie Furihata; S Yonezawa; Kazumasa Miki
Fetal rat glandular stomach epithelial cells differentiate into surface mucous cells which express cathepsin E in the absence of mesenchymal cells in primary culture.
Differentiation; research in biological diversity 1994;56(1-2):83-9.
1992: S Tsukada; Masao Ichinose; Kazumasa Miki; Masae Tatematsu; S Yonezawa; M Matsushima; N Kakei; Hiroshi Fukamachi; Sadao Yasugi; Kiyoshi Kurokawa
Tissue- and cell-specific control of guinea pig cathepsin E gene expression.
Biochemical and biophysical research communications 1992;187(3):1401-8.
1988: Arinobu Tojo; Hiroshi Fukamachi; T Saito; M Kasuga; A Urabe; F Takaku
Induction of the receptor for erythropoietin in murine erythroleukemia cells after dimethyl sulfoxide treatment.
Cancer research 1988;48(7):1818-22.
1988: C J Tsao; Arinobu Tojo; Hiroshi Fukamachi; T Kitamura; T Saito; A Urabe; F Takaku
Expression of the functional erythropoietin receptors on interleukin 3-dependent murine cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(1):89-93.
1987: Arinobu Tojo; Hiroshi Fukamachi; M Kasuga; A Urabe; F Takaku
Identification of erythropoietin receptors on fetal liver erythroid cells.
Biochemical and biophysical research communications 1987;148(1):443-8.