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Akiyoshi Fukamizu

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Araya Natsumi; Arimura Hitoshi; Kawahara Ko-ichi; Yagishita Naoko; Ishida Junji; Fujii Ryoji; Aratani Satoko; Fujita Hidetoshi; Sato Tomoo; Yamano Yoshihisa; Higuchi Itsuro; Osame Mitsuhiro; Nishioka Kusuki; Fukamizu Akiyoshi; Arimura Kimiyoshi; Maruyama Ikuro; Nakajima Toshihiro
Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase.
Sugawara Michiko; Okamoto Kiyoshi; Kadowaki Tadashi; Kusano Kazutomi; Fukamizu Akiyoshi; Yoshimura Tsutomu
Inoculation of human tumor cells alters the Basal expression but not the inducibility of cytochrome P450 enzymes in tumor-bearing mouse liver.
Kurosaka Maya; Suzuki Tatsunori; Hosono Kanako; Kamata Yuji; Fukamizu Akiyoshi; Kitasato Hidero; Fujita Yoshikuni; Majima Masataka
Reduced angiogenesis and delay in wound healing in angiotensin II type 1a receptor-deficient mice.

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All Publications

2009: Araya Natsumi; Arimura Hitoshi; Kawahara Ko-ichi; Yagishita Naoko; Ishida Junji; Fujii Ryoji; Aratani Satoko; Fujita Hidetoshi; Sato Tomoo; Yamano Yoshihisa; Higuchi Itsuro; Osame Mitsuhiro; Nishioka Kusuki; Fukamizu Akiyoshi; Arimura Kimiyoshi; Maruyama Ikuro; Nakajima Toshihiro
Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase.
International journal of molecular medicine 2009;24(5):605-11.
2009: Sugawara Michiko; Okamoto Kiyoshi; Kadowaki Tadashi; Kusano Kazutomi; Fukamizu Akiyoshi; Yoshimura Tsutomu
Inoculation of human tumor cells alters the Basal expression but not the inducibility of cytochrome P450 enzymes in tumor-bearing mouse liver.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(11):2244-54.
2009: Kurosaka Maya; Suzuki Tatsunori; Hosono Kanako; Kamata Yuji; Fukamizu Akiyoshi; Kitasato Hidero; Fujita Yoshikuni; Majima Masataka
Reduced angiogenesis and delay in wound healing in angiotensin II type 1a receptor-deficient mice.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2009;63(9):627-34.
2009: Matsuzaki Hitomi; Okamura Eiichi; Shimotsuma Motoshi; Fukamizu Akiyoshi; Tanimoto Keiji
A randomly integrated transgenic H19 imprinting control region acquires methylation imprinting independently of its establishment in germ cells.
Molecular and cellular biology 2009;29(17):4595-603.
2009: Yamagata Kazuyuki; Daitoku Hiroaki; Fukamizu Akiyoshi
[Regulation of cellular functions by arginine methylation]
Seikagaku. The Journal of Japanese Biochemical Society 2009;81(8):688-99.
2009: Satofuka Shingo; Ichihara Atsuhiro; Nagai Norihiro; Noda Kousuke; Ozawa Yoko; Fukamizu Akiyoshi; Tsubota Kazuo; Itoh Hiroshi; Oike Yuichi; Ishida Susumu
(Pro)renin receptor-mediated signal transduction and tissue renin-angiotensin system contribute to diabetes-induced retinal inflammation.
Diabetes 2009;58(7):1625-33.
2009: Sakamaki Jun-ichi; Daitoku Hiroaki; Yoshimochi Kenji; Miwa Masanao; Fukamizu Akiyoshi
Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1.
Biochemical and biophysical research communications 2009;382(3):497-502.
2009: Hara Yasuhiro; Onishi Yoshiaki; Oishi Katsutaka; Miyazaki Koyomi; Fukamizu Akiyoshi; Ishida Norio
Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter.
Nucleic acids research 2009;37(4):1115-26.
2009: Sako Keisuke; Fukuhara Shigetomo; Minami Takashi; Hamakubo Takao; Song Haihua; Kodama Tatsuhiko; Fukamizu Akiyoshi; Gutkind J Silvio; Koh Gou Young; Mochizuki Naoki
Angiopoietin-1 induces Kruppel-like factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2.
The Journal of biological chemistry 2009;284(9):5592-601.
2009: Asaba Yutaro; Ito Masako; Fumoto Toshio; Watanabe Ken; Fukuhara Ryoji; Takeshita Sunao; Nimura Yuji; Ishida Junji; Fukamizu Akiyoshi; Ikeda Kyoji
Activation of renin-angiotensin system induces osteoporosis independently of hypertension.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009;24(2):241-50.
2009: Ito Yu; Daitoku Hiroaki; Fukamizu Akiyoshi
Foxo1 increases pro-inflammatory gene expression by inducing C/EBPbeta in TNF-alpha-treated adipocytes.
Biochemical and biophysical research communications 2009;378(2):290-5.
2008: Sakairi Akira; Ishida Junji; Honjo Kaori; Inaba Saki; Nakamura Shoko; Sugiyama Fumihiro; Yagami Ken-Ichi; Fukamizu Akiyoshi
Angiotensin type 1 receptor blockade prevents cardiac remodeling in mice with pregnancy-associated hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(12):2165-75.
2008: Satofuka Shingo; Ichihara Atsuhiro; Nagai Norihiro; Noda Kousuke; Ozawa Yoko; Fukamizu Akiyoshi; Tsubota Kazuo; Itoh Hiroshi; Oike Yuichi; Ishida Susumu
(Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.
The American journal of pathology 2008;173(6):1911-8.
2008: Hirota Keiko; Sakamaki Jun-ichi; Ishida Junji; Shimamoto Yoko; Nishihara Shigeki; Kodama Norio; Ohta Kazuhide; Yamamoto Masayuki; Tanimoto Keiji; Fukamizu Akiyoshi
A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding.
The Journal of biological chemistry 2008;283(47):32432-41.
2008: Yamagata Kazuyuki; Daitoku Hiroaki; Takahashi Yuta; Namiki Kana; Hisatake Koji; Kako Koichiro; Mukai Hidehito; Kasuya Yoshitoshi; Fukamizu Akiyoshi
Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt.
Molecular cell 2008;32(2):221-31.
2008: Hamada Juri; Kimura Junko; Ishida Junji; Kohda Takeo; Morishita Setsuo; Ichihara Shigeyasu; Fukamizu Akiyoshi
Evaluation of novel cyclic analogues of apelin.
International journal of molecular medicine 2008;22(4):547-52.
2008: Kim Jun-Dal; Kako Koichiro; Kakiuchi Misako; Park Gwi Gun; Fukamizu Akiyoshi
EWS is a substrate of type I protein arginine methyltransferase, PRMT8.
International journal of molecular medicine 2008;22(3):309-15.
2008: Ohno Osamu; Ye Mao; Koyama Tomoyuki; Yazawa Kazunaga; Mura Emi; Matsumoto Hiroshi; Ichino Takao; Yamada Kaoru; Nakamura Kazuhiko; Ohno Tomohiro; Yamaguchi Kohji; Ishida Junji; Fukamizu Akiyoshi; Uemura Daisuke
Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension.
Bioorganic & medicinal chemistry 2008;16(16):7843-52.
2008: Yayama Katsutoshi; Miyagi Ryoko; Sugiyama Kaori; Sugaya Takeshi; Fukamizu Akiyoshi; Okamoto Hiroshi
Angiotensin II regulates liver regeneration via type 1 receptor following partial hepatectomy in mice.
Biological & pharmaceutical bulletin 2008;31(7):1356-61.
2008: Asada Sachie; Ikeda Akemi; Nagao Rina; Hama Hiroshi; Sudo Tatsuhiko; Fukamizu Akiyoshi; Kasuya Yoshitoshi; Kishi Tsutomu
Oxidative stress-induced ubiquitination of RCAN1 mediated by SCFbeta-TrCP ubiquitin ligase.
International journal of molecular medicine 2008;22(1):95-104.
2008: Kato Hideki; Ishida Junji; Nagano Katsumasa; Honjo Kaori; Sugaya Takeshi; Takeda Norifumi; Sugiyama Fumihiro; Yagami Ken-Ichi; Fujita Toshiro; Nangaku Masaomi; Fukamizu Akiyoshi
Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells.
Laboratory investigation; a journal of technical methods and pathology 2008;88(7):731-9.
2008: Murayama Akiko; Ohmori Kazuji; Fujimura Akiko; Minami Hiroshi; Yasuzawa-Tanaka Kayoko; Kuroda Takao; Oie Shohei; Daitoku Hiroaki; Okuwaki Mitsuru; Nagata Kyosuke; Fukamizu Akiyoshi; Kimura Keiji; Shimizu Toshiyuki; Yanagisawa Junn
Epigenetic control of rDNA loci in response to intracellular energy status.
Cell 2008;133(4):627-39.
2008: Furuya Mitsuko; Ishida Junji; Inaba Saki; Kasuya Yoshitoshi; Kimura Sadao; Nemori Ryoichi; Fukamizu Akiyoshi
Impaired placental neovascularization in mice with pregnancy-associated hypertension.
Laboratory investigation; a journal of technical methods and pathology 2008;88(4):416-29.
2008: Lu Hong; Rateri Debra L; Feldman David L; Jr Richard J Charnigo; Fukamizu Akiyoshi; Ishida Junji; Oesterling Elizabeth G; Cassis Lisa A; Daugherty Alan
Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice.
The Journal of clinical investigation 2008;118(3):984-93.
2008: Tanimoto Keiji; Sugiura Akiko; Kanafusa Sumiyo; Saito Tomoko; Masui Naoto; Yanai Kazuyuki; Fukamizu Akiyoshi
A single nucleotide mutation in the mouse renin promoter disrupts blood pressure regulation.
The Journal of clinical investigation 2008;118(3):1006-16.
2008: Furuya Mitsuko; Ishida Junji; Aoki Ichiro; Fukamizu Akiyoshi
Pathophysiology of placentation abnormalities in pregnancy-induced hypertension.
Vascular health and risk management 2008;4(6):1301-13.
2007: Hashimoto Tatsuo; Kihara Minoru; Imai Nozomi; Yoshida Shin-Ichiro; Shimoyamada Hiroaki; Yasuzaki Hiroaki; Ishida Junji; Toya Yoshiyuki; Kiuchi Yoshihiro; Hirawa Nobuhito; Tamura Kouichi; Yazawa Takuya; Kitamura Hitoshi; Fukamizu Akiyoshi; Umemura Satoshi
Requirement of apelin-apelin receptor system for oxidative stress-linked atherosclerosis.
The American journal of pathology 2007;171(5):1705-12.
2007: Umemura Mariko; Fujita Morihisa; Yoko-O Takehiko; Fukamizu Akiyoshi; Jigami Yoshifumi
Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramides.
Molecular biology of the cell 2007;18(11):4304-16.
2007: Nakanishi Michio; Harada Masaki; Kishimoto Ichiro; Kuwahara Koichiro; Kawakami Rika; Nakagawa Yasuaki; Yasuno Shinji; Usami Satoru; Kinoshita Hideyuki; Adachi Yuichiro; Fukamizu Akiyoshi; Saito Yoshihiko; Nakao Kazuwa
Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation.
Circulation journal : official journal of the Japanese Circulation Society 2007;71(8):1310-6.
2007: Sekine Keisuke; Chen Yen-Rong; Kojima Nobuhiko; Ogata Kazuhiro; Fukamizu Akiyoshi; Miyajima Atsushi
Foxo1 links insulin signaling to C/EBPalpha and regulates gluconeogenesis during liver development.
The EMBO journal 2007;26(15):3607-15.
2007: Shimotsuma Motoshi; Matsuzaki Hitomi; Tanabe Osamu; Campbell Andrew D; Engel James Douglas; Fukamizu Akiyoshi; Tanimoto Keiji
Linear distance from the locus control region determines epsilon-globin transcriptional activity.
Molecular and cellular biology 2007;27(16):5664-72.
2007: Daitoku Hiroaki; Fukamizu Akiyoshi
FOXO transcription factors in the regulatory networks of longevity.
Journal of biochemistry 2007;141(6):769-74.
2007: Zhang Jianyong; Hosoya Tomonori; Maruyama Atsushi; Nishikawa Keizo; Maher Jonathan M; Ohta Tsutomu; Motohashi Hozumi; Fukamizu Akiyoshi; Shibahara Shigeki; Itoh Ken; Yamamoto Masayuki
Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.
The Biochemical journal 2007;404(3):459-66.
2007: Yamagata Kazuyuki; Yoshimochi Kenji; Daitoku Hiroaki; Hirota Keiko; Fukamizu Akiyoshi
Bile acid represses the peroxisome proliferator-activated receptor-gamma coactivator-1 promoter activity in a small heterodimer partner-dependent manner.
International journal of molecular medicine 2007;19(5):751-6.
2007: Fan WuQiang; Yanase Toshihiko; Morinaga Hidetaka; Okabe Taijiro; Nomura Masatoshi; Daitoku Hiroaki; Fukamizu Akiyoshi; Kato Shigeaki; Takayanagi Ryoichi; Nawata Hajime
Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor.
The Journal of biological chemistry 2007;282(10):7329-38.
2007: Asada Sachie; Daitoku Hiroaki; Matsuzaki Hitomi; Saito Tomoko; Sudo Tatsuhiko; Mukai Hidehito; Iwashita Shintaro; Kako Koichiro; Kishi Tsutomu; Kasuya Yoshitoshi; Fukamizu Akiyoshi
Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.
Cellular signalling 2007;19(3):519-27.
2006: Nakae Jun; Cao Yongheng; Daitoku Hiroaki; Fukamizu Akiyoshi; Ogawa Wataru; Yano Yoshihiko; Hayashi Yoshitake
The LXXLL motif of murine forkhead transcription factor FoxO1 mediates Sirt1-dependent transcriptional activity.
The Journal of clinical investigation 2006;116(9):2473-83.
2006: Aoyama Hisanori; Daitoku Hiroaki; Fukamizu Akiyoshi
Nutrient control of phosphorylation and translocation of Foxo1 in C57BL/6 and db/db mice.
International journal of molecular medicine 2006;18(3):433-9.
2006: Marchetti Valentina; Menghini Rossella; Rizza Stefano; Vivanti Alessia; Feccia Tiziana; Lauro Davide; Fukamizu Akiyoshi; Lauro Renato; Federici Massimo
Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling.
Diabetes 2006;55(8):2231-7.
2006: Fukamizu Akiyoshi
[Genetic dissection of the renin-angiotensin system]
Nippon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 5():273-7.
2006: Hashimoto Tatsuo; Kihara Minoru; Ishida Junji; Imai Nozomi; Yoshida Shin-ichiro; Toya Yoshiyuki; Fukamizu Akiyoshi; Kitamura Hitoshi; Umemura Satoshi
Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(6):1267-72.
2006: Utsunomiya Ryuji; Suto Kyoko; Balasundaresan Dhakshnamoorthy; Fukamizu Akiyoshi; Kumar Penmetcha K R; Mizuno Hiroshi
Structure of an RNA duplex r(GGCGBrUGCGCU)2 with terminal and internal tandem G.U base pairs.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 3):331-8.
2006: Hatta Mitsutoki; Yoshimura Yoshitaka; Deyama Yoshiaki; Fukamizu Akiyoshi; Suzuki Kuniaki
Molecular characterization of the zinc finger transcription factor, Osterix.
International journal of molecular medicine 2006;17(3):425-30.
2006: Aratani Satoko; Oishi Takayuki; Fujita Hidetoshi; Nakazawa Minako; Fujii Ryouji; Imamoto Naoko; Yoneda Yoshihiro; Fukamizu Akiyoshi; Nakajima Toshihiro
The nuclear import of RNA helicase A is mediated by importin-alpha3.
Biochemical and biophysical research communications 2006;340(1):125-33.
2006: Hashimoto Tatsuo; Kihara Minoru; Sato Keiko; Matsushita Kei; Tanimoto Keiji; Toya Yoshiyuki; Fukamizu Akiyoshi; Umemura Satoshi
Expression of cyclooxygenase-2 in the juxtaglomerular apparatus of angiotensinogen gene-knockout mice.
Nephron. Physiology 2006;102(1):p1-8.
2005: Nakahara Mayuko; Furuya Norihiko; Takagaki Kentaro; Sugaya Takeshi; Hirota Keiko; Fukamizu Akiyoshi; Kanda Tatsuo; Fujii Hiroshi; Sato Ryuichiro
Ileal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestine.
The Journal of biological chemistry 2005;280(51):42283-9.
2005: Kato Hideki; Ishida Junji; Imagawa Shigehiko; Saito Tomoko; Suzuki Norio; Matsuoka Toshiki; Sugaya Takeshi; Tanimoto Keiji; Yokoo Takashi; Ohneda Osamu; Sugiyama Fumihiro; Yagami Ken-ichi; Fujita Toshiro; Yamamoto Masayuki; Nangaku Masaomi; Fukamizu Akiyoshi
Enhanced erythropoiesis mediated by activation of the renin-angiotensin system via angiotensin II type 1a receptor.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):2023-5.
2005: Hashimoto Yasumi; Ishida Junji; Yamamoto Rie; Fujiwara Kae; Asada Sachie; Kasuya Yoshitoshi; Mochizuki Naoki; Fukamizu Akiyoshi
G protein-coupled APJ receptor signaling induces focal adhesion formation and cell motility.
International journal of molecular medicine 2005;16(5):787-92.
2005: Suzuki Nobuhiro; Fujimoto Zui; Morita Takashi; Fukamizu Akiyoshi; Mizuno Hiroshi
pH-Dependent structural changes at Ca(2+)-binding sites of coagulation factor IX-binding protein.
Journal of molecular biology 2005;353(1):80-7.
2005: Matsuzaki Hitomi; Daitoku Hiroaki; Hatta Mitsutoki; Aoyama Hisanori; Yoshimochi Kenji; Fukamizu Akiyoshi
Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11278-83.
2005: Tsuchimochi Kaneyuki; Yagishita Naoko; Yamasaki Satoshi; Amano Tetsuya; Kato Yukihiro; Kawahara Ko-ichi; Aratani Satoko; Fujita Hidetoshi; Ji Fengyun; Sugiura Akiko; Izumi Toshihiko; Sugamiya Asako; Maruyama Ikuro; Fukamizu Akiyoshi; Komiya Setsuro; Nishioka Kusuki; Nakajima Toshihiro
Identification of a crucial site for synoviolin expression.
Molecular and cellular biology 2005;25(16):7344-56.
2005: Nakanishi Michio; Saito Yoshihiko; Kishimoto Ichiro; Harada Masaki; Kuwahara Koichiro; Takahashi Nobuki; Kawakami Rika; Nakagawa Yasuaki; Tanimoto Keiji; Yasuno Shinji; Usami Satoru; Li Yuhao; Adachi Yuichiro; Fukamizu Akiyoshi; Garbers David L; Nakao Kazuwa
Role of natriuretic peptide receptor guanylyl cyclase-A in myocardial infarction evaluated using genetically engineered mice.
Hypertension 2005;46(2):441-7.
2005: Kouyama Ryuji; Suganami Takayoshi; Nishida Junko; Tanaka Miyako; Toyoda Takuya; Kiso Minako; Chiwata Tsuyoshi; Miyamoto Yoshihiro; Yoshimasa Yasunao; Fukamizu Akiyoshi; Horiuchi Masatsugu; Hirata Yukio; Ogawa Yoshihiro
Attenuation of diet-induced weight gain and adiposity through increased energy expenditure in mice lacking angiotensin II type 1a receptor.
Endocrinology 2005;146(8):3481-9.
2005: Tanimoto Keiji; Shimotsuma Motoshi; Matsuzaki Hitomi; Omori Akane; Bungert Jörg; Engel James Douglas; Fukamizu Akiyoshi
Genomic imprinting recapitulated in the human beta-globin locus.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(29):10250-5.
2005: Imai Yumiko; Kuba Keiji; Rao Shuan; Huan Yi; Guo Feng; Guan Bin; Yang Peng; Sarao Renu; Wada Teiji; Leong-Poi Howard; Crackower Michael A; Fukamizu Akiyoshi; Hui Chi-Chung; Hein Lutz; Uhlig Stefan; Slutsky Arthur S; Jiang Chengyu; Penninger Josef M
Angiotensin-converting enzyme 2 protects from severe acute lung failure.
Nature 2005;436(7047):112-6.
2005: Daitoku Hiroaki; Fukamizu Akiyoshi
[FOXO: the regulator of metabolism, longevity, and aging]
Seikagaku. The Journal of Japanese Biochemical Society 2005;77(5):423-7.
2005: Omori Akane; Tanabe Osamu; Engel James Douglas; Fukamizu Akiyoshi; Tanimoto Keiji
Adult stage gamma-globin silencing is mediated by a promoter direct repeat element.
Molecular and cellular biology 2005;25(9):3443-51.
2005: Dateki Minori; Horii Takuro; Kasuya Yoshitoshi; Mochizuki Reiko; Nagao Yasumitsu; Ishida Junji; Sugiyama Fumihiro; Tanimoto Keiji; Yagami Ken-Ichi; Imai Hiroshi; Fukamizu Akiyoshi
Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in epileptic seizure.
The Journal of biological chemistry 2005;280(21):20503-8.
2005: Takimoto-Ohnishi Eriko; Saito Tomoko; Ishida Junji; Ohnishi Junji; Sugiyama Fumihiro; Yagami Ken-Ichi; Fukamizu Akiyoshi
Differential roles of renin and angiotensinogen in the feto-maternal interface in the development of complications of pregnancy.
Molecular endocrinology (Baltimore, Md.) 2005;19(5):1361-72.
2005: Shimizu Taku; Oishi Takayuki; Omori Akane; Sugiura Akiko; Hirota Keiko; Aoyama Hisanori; Saito Tomoko; Sugaya Takeshi; Kon Yasuhiro; Engel James Douglas; Fukamizu Akiyoshi; Tanimoto Keiji
Identification of cis-regulatory sequences in the human angiotensinogen gene by transgene coplacement and site-specific recombination.
Molecular and cellular biology 2005;25(8):2938-45.
2005: Fujita Hidetoshi; Ohshima Takayuki; Oishi Takayuki; Aratani Satoko; Fujii Ryouji; Fukamizu Akiyoshi; Nakajima Toshihiro
Relevance of nuclear localization and functions of RNA helicase A.
International journal of molecular medicine 2005;15(4):555-60.
2005: Araya Natsumi; Hiraga Hideaki; Kako Koichiro; Arao Yukitomo; Kato Shigeaki; Fukamizu Akiyoshi
Transcriptional down-regulation through nuclear exclusion of EWS methylated by PRMT1.
Biochemical and biophysical research communications 2005;329(2):653-60.
2005: Fukamizu Akiyoshi
[Genetic dissection of the renin-angiotensin system]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 3():42-8.
2005: Fukamizu Akiyoshi
[A new paradigm for renin research]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 3():12-6.
2005: Hirota Keiko; Aoyama Hisanori; Fukamizu Akiyoshi
Mutation analysis of HNF-4 binding sites in the human glucose-6-phosphatase promoter.
International journal of molecular medicine 2005;15(3):487-90.
2005: Yagishita Naoko; Ohneda Kinuko; Amano Tetsuya; Yamasaki Satoshi; Sugiura Akiko; Tsuchimochi Kaneyuki; Shin Hiroshi; Kawahara Ko-Ichi; Ohneda Osamu; Ohta Tomohiko; Tanaka Sakae; Yamamoto Masayuki; Maruyama Ikuro; Nishioka Kusuki; Fukamizu Akiyoshi; Nakajima Toshihiro
Essential role of synoviolin in embryogenesis.
The Journal of biological chemistry 2005;280(9):7909-16.
2005: Fujita Mamoru; Hayashi Izumi; Yamashina Shohei; Fukamizu Akiyoshi; Itoman Moritoshi; Majima Masataka
Angiotensin type 1a receptor signaling-dependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor growth.
Carcinogenesis 2005;26(2):271-9.
2005: Kunori Yuichi; Muroga Yumiko; Iidaka Minako; Mitsuhashi Hiroaki; Kamimura Takashi; Fukamizu Akiyoshi
Species differences in angiotensin II generation and degradation by mast cell chymases.
Journal of receptor and signal transduction research 2005;25(1):35-44.
2004: Asada Sachie; Takanami-Ohnishi Yoko; Zhou Jing; Hama Hiroshi; Fukamizu Akiyoshi; Kimura Sadao; Goto Katsutoshi; Kasuya Yoshitoshi
Cytodifferentiation enhances Erk activation induced by endothelin-1 in primary cultured astrocytes.
Journal of cardiovascular pharmacology 2004;44 Suppl 1():S307-12.
2004: Kako Koichiro; Takehara Akio; Arai Hidenori; Onodera Takashi; Takahashi Yoshinori; Hanagata Hiroshi; Ogra Yasumitsu; Takagi Hiroaki; Kodama Hiroko; Suzuki Kazuo T; Munekata Eisuke; Fukamizu Akiyoshi
A selective requirement for copper-dependent activation of cytochrome c oxidase by Cox17p.
Biochemical and biophysical research communications 2004;324(4):1379-85.
2004: Kamijo Atsuko; Sugaya Takeshi; Hikawa Akihisa; Okada Mitsuhiro; Okumura Fumikazu; Yamanouchi Masaya; Honda Akiko; Okabe Masaru; Fujino Tomoya; Hirata Yasunobu; Omata Masao; Kaneko Ritsuko; Fujii Hiroshi; Fukamizu Akiyoshi; Kimura Kenjiro
Urinary excretion of fatty acid-binding protein reflects stress overload on the proximal tubules.
The American journal of pathology 2004;165(4):1243-55.
2004: Mochizuki-Sakisaka Reiko; Dateki Minori; Ishizuka Yasuyuki; Yanai Kazuyuki; Matsuda Yoichi; Koga Yoshihiko; Fukamizu Akiyoshi
Structural organization of the mouse neurochondrin gene.
International journal of molecular medicine 2004;14(3):361-6.
2004: Kunori Yuichi; Hase Naoki; Kawamura Takashi; Sato Hiroaki; Kasai Hidenori; Muroga Yumiko; Kamimura Takashi; Fukamizu Akiyoshi
Generation and characterization of new monoclonal antibodies against human chymase.
Hybridoma and hybridomics 2004;23(4):237-43.
2004: Daitoku Hiroaki; Hatta Mitsutoki; Matsuzaki Hitomi; Aratani Satoko; Ohshima Takayuki; Miyagishi Makoto; Nakajima Toshihiro; Fukamizu Akiyoshi
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10042-7.
2004: Sato Keiko; Kihara Minoru; Hashimoto Tatsuo; Matsushita Kei; Koide Yu-Ichi; Tamura Koichi; Hirawa Nobuhito; Toya Yoshiyuki; Fukamizu Akiyoshi; Umemura Satoshi
Alterations in renal endothelial nitric oxide synthase expression by salt diet in angiotensin type-1a receptor gene knockout mice.
Journal of the American Society of Nephrology : JASN 2004;15(7):1756-63.
2004: Zou Yunzeng; Akazawa Hiroshi; Qin Yingjie; Sano Masanori; Takano Hiroyuki; Minamino Tohru; Makita Noriko; Iwanaga Koji; Zhu Weidong; Kudoh Sumiyo; Toko Haruhiro; Tamura Koichi; Kihara Minoru; Nagai Toshio; Fukamizu Akiyoshi; Umemura Satoshi; Iiri Taroh; Fujita Toshiro; Komuro Issei
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II.
Nature cell biology 2004;6(6):499-506.
2004: Ishida Junji; Hashimoto Tatsuo; Hashimoto Yasumi; Nishiwaki Shiro; Iguchi Taku; Harada Shuichi; Sugaya Takeshi; Matsuzaki Hitomi; Yamamoto Rie; Shiota Naotaka; Okunishi Hideki; Kihara Minoru; Umemura Satoshi; Sugiyama Fumihiro; Yagami Ken-Ichi; Kasuya Yoshitoshi; Mochizuki Naoki; Fukamizu Akiyoshi
Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo.
The Journal of biological chemistry 2004;279(25):26274-9.
2004: Shimamoto Yoko; Hirota Keiko; Fukamizu Akiyoshi
Effect of peroxisome proliferator-activated receptor alpha on human angiotensinogen promoter.
International journal of molecular medicine 2004;13(5):729-33.
2004: Date Shoichi; Nibu Yutaka; Yanai Kazuyuki; Hirata Jun; Yagami Ken-Ichi; Fukamizu Akiyoshi
Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogen gene.
International journal of molecular medicine 2004;13(5):637-42.
2004: Yamagata Kazuyuki; Daitoku Hiroaki; Shimamoto Yoko; Matsuzaki Hitomi; Hirota Keiko; Ishida Junji; Fukamizu Akiyoshi
Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1.
The Journal of biological chemistry 2004;279(22):23158-65.
2004: Ide Tomohiro; Shimano Hitoshi; Yahagi Naoya; Matsuzaka Takashi; Nakakuki Masanori; Yamamoto Takashi; Nakagawa Yoshimi; Takahashi Akimitsu; Suzuki Hiroaki; Sone Hirohito; Toyoshima Hideo; Fukamizu Akiyoshi; Yamada Nobuhiro
SREBPs suppress IRS-2-mediated insulin signalling in the liver.
Nature cell biology 2004;6(4):351-7.
2004: Ohashi Hirokazu; Takagi Hitoshi; Oh Hideyasu; Suzuma Kiyoshi; Suzuma Izumi; Miyamoto Noriko; Uemura Akiyoshi; Watanabe Daisuke; Murakami Tomoaki; Sugaya Takeshi; Fukamizu Akiyoshi; Honda Yoshihito
Phosphatidylinositol 3-kinase/Akt regulates angiotensin II-induced inhibition of apoptosis in microvascular endothelial cells by governing survivin expression and suppression of caspase-3 activity.
Circulation research 2004;94(6):785-93.
2004: Ieda Masaki; Fukuda Keiichi; Hisaka Yasuyo; Kimura Kensuke; Kawaguchi Haruko; Fujita Jun; Shimoda Kouji; Takeshita Eiko; Okano Hideyuki; Kurihara Yukiko; Kurihara Hiroki; Ishida Junji; Fukamizu Akiyoshi; Federoff Howard J; Ogawa Satoshi
Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression.
The Journal of clinical investigation 2004;113(6):876-84.
2004: Dateki Minori; Mochizuki Reiko; Yanai Kazuyuki; Fukamizu Akiyoshi
Identification of the mouse neurochondrin promoter region and the responsible region for cell type specific gene regulation.
Neuroscience letters 2004;356(2):107-10.
2004: Saito Tomoko; Ishida Junji; Takimoto-Ohnishi Eriko; Takamine Shoko; Shimizu Taku; Sugaya Takeshi; Kato Hideki; Matsuoka Toshiki; Nangaku Masaomi; Kon Yasuhiro; Sugiyama Fumihiro; Yagami Ken-ichi; Fukamizu Akiyoshi
An essential role for angiotensin II type 1a receptor in pregnancy-associated hypertension with intrauterine growth retardation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(2):388-90.
2004: Shimamoto Yoko; Ishida Junji; Yamagata Kazuyuki; Saito Tomoko; Kato Hideki; Matsuoka Toshiki; Hirota Keiko; Daitoku Hiroaki; Nangaku Masaomi; Yamagata Kazuya; Fujii Hiroshi; Takeda Jun; Fukamizu Akiyoshi
Inhibitory effect of the small heterodimer partner on hepatocyte nuclear factor-4 mediates bile acid-induced repression of the human angiotensinogen gene.
The Journal of biological chemistry 2004;279(9):7770-6.
2004: Li Yuhao; Kishimoto Ichiro; Saito Yoshihiko; Harada Masaki; Kuwahara Koichiro; Izumi Takehiko; Hamanaka Ichiro; Takahashi Nobuki; Kawakami Rika; Tanimoto Keiji; Nakagawa Yasuaki; Nakanishi Michio; Adachi Yuichiro; Garbers David L; Fukamizu Akiyoshi; Nakao Kazuwa
Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A.
Endocrinology 2004;145(2):951-8.
2004: Maki Shinichi; Miyauchi Takashi; Kakinuma Yoshihiko; Sakai Satoshi; Kobayashi Tsutomu; Sugiyama Fumihiro; Fukamizu Akiyoshi; Goto Katsutoshi; Yamaguchi Iwao
The endothelin receptor antagonist ameliorates the hypertensive phenotypes of transgenic hypertensive mice with renin-angiotensin genes and discloses roles of organ specific activation of endothelin system in transgenic mice.
Life sciences 2004;74(9):1105-18.
2003: Tanimoto Keiji; Sugiura Akiko; Omori Akane; Felsenfeld Gary; Engel James Douglas; Fukamizu Akiyoshi
Human beta-globin locus control region HS5 contains CTCF- and developmental stage-dependent enhancer-blocking activity in erythroid cells.
Molecular and cellular biology 2003;23(24):8946-52.
2003: Okada Hirokazu; Watanabe Yusuke; Inoue Tsutomu; Kobayashi Tatsuya; Kanno Yoshihiko; Shiota Goshi; Nakamura Toshikazu; Sugaya Takeshi; Fukamizu Akiyoshi; Suzuki Hiromichi
Transgene-derived hepatocyte growth factor attenuates reactive renal fibrosis in aristolochic acid nephrotoxicity.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(12):2515-23.
2003: Mochizuki Reiko; Dateki Minori; Yanai Kazuyuki; Ishizuka Yasuyuki; Amizuka Norio; Kawashima Hiroyuki; Koga Yoshihiko; Ozawa Hidehiro; Fukamizu Akiyoshi
Targeted disruption of the neurochondrin/norbin gene results in embryonic lethality.
Biochemical and biophysical research communications 2003;310(4):1219-26.
2003: Amano Tetsuya; Yamasaki Satoshi; Yagishita Naoko; Tsuchimochi Kaneyuki; Shin Hiroshi; Kawahara Ko-ichi; Aratani Satoko; Fujita Hidetoshi; Zhang Lei; Ikeda Rie; Fujii Ryoji; Miura Naoki; Komiya Setsuro; Nishioka Kusuki; Maruyama Ikuro; Fukamizu Akiyoshi; Nakajima Toshihiro
Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy.
Genes & development 2003;17(19):2436-49.
2003: Fukuoka Masahiro; Daitoku Hiroaki; Hatta Mitsutoki; Matsuzaki Hitomi; Umemura Satoshi; Fukamizu Akiyoshi
Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation.
International journal of molecular medicine 2003;12(4):503-8.
2003: Matsuzaki Hitomi; Daitoku Hiroaki; Hatta Mitsutoki; Tanaka Keiji; Fukamizu Akiyoshi
Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11285-90.
2003: Aratani Satoko; Fujii Ryouji; Fujita Hidetoshi; Fukamizu Akiyoshi; Nakajima Toshihiro
Aromatic residues are required for RNA helicase A mediated transactivation.
International journal of molecular medicine 2003;12(2):175-80.
2003: Saito Tomoko; Oishi Takayuki; Yanai Kazuyuki; Shimamoto Yoko; Fukamizu Akiyoshi
Cloning and characterization of a novel splicing isoform of USF1.
International journal of molecular medicine 2003;12(2):161-7.
2003: Uehara Sayuri; Tsuchida Minoru; Kanno Tetsuya; Sasaki Minoru; Nishikibe Masaru; Fukamizu Akiyoshi
Late-onset obesity in mice transgenic for the human renin gene.
International journal of molecular medicine 2003;11(6):723-7.
2003: Fujita Hidetoshi; Fujii Ryouji; Aratani Satoko; Amano Tetsuya; Fukamizu Akiyoshi; Nakajima Toshihiro
Antithetic effects of MBD2a on gene regulation.
Molecular and cellular biology 2003;23(8):2645-57.
2003: Hirota Keiko; Daitoku Hiroaki; Matsuzaki Hitomi; Araya Natsumi; Yamagata Kazuyuki; Asada Sachie; Sugaya Takeshi; Fukamizu Akiyoshi
Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor.
The Journal of biological chemistry 2003;278(15):13056-60.
2003: Nishinokubi Izumi; Shimoda Masami; Kako Koichiro; Sakai Takaomi; Fukamizu Akiyoshi; Ishida Norio
Highly conserved Drosophila ananassae timeless gene functions as a clock component in Drosophila melanogaster.
Gene 2003;307():183-90.
2003: Daitoku Hiroaki; Yamagata Kazuyuki; Matsuzaki Hitomi; Hatta Mitsutoki; Fukamizu Akiyoshi
Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.
Diabetes 2003;52(3):642-9.
2003: Araya Natsumi; Hirota Keiko; Shimamoto Yoko; Miyagishi Makoto; Yoshida Eisaku; Ishida Junji; Kaneko Setsuko; Kaneko Michio; Nakajima Toshihiro; Fukamizu Akiyoshi
Cooperative interaction of EWS with CREB-binding protein selectively activates hepatocyte nuclear factor 4-mediated transcription.
The Journal of biological chemistry 2003;278(7):5427-32.
2002: Kunori Yuichi; Koizumi Masahiro; Masegi Tsukio; Kasai Hidenori; Kawabata Hiroshi; Yamazaki Yuzo; Fukamizu Akiyoshi
Rodent alpha-chymases are elastase-like proteases.
European journal of biochemistry / FEBS 2002;269(23):5921-30.
2002: Sano Masayuki; Kuwabara Tomoko; Warashina Masaki; Fukamizu Akiyoshi; Taira Kazunari
Novel method for selection of tRNA-driven ribozymes with enhanced stability in mammalian cells.
Antisense & nucleic acid drug development 2002;12(5):341-52.
2002: Li Yuhao; Kishimoto Ichiro; Saito Yoshihiko; Harada Masaki; Kuwahara Koichiro; Izumi Takehiko; Takahashi Nobuki; Kawakami Rika; Tanimoto Keiji; Nakagawa Yasuaki; Nakanishi Michio; Adachi Yuichiro; Garbers David L; Fukamizu Akiyoshi; Nakao Kazuwa
Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart.
Circulation 2002;106(13):1722-8.
2002: Nakazawa Minako; Aratani Satoko; Hatta Mitsutoki; Araya Natsumi; Daitoku Hiroaki; Kawahara Ko-Ichi; Watanabe Shin-Ichi; Nakamura Hiroshi; Yoshino Shin-Ichi; Fujii Ryouji; Fujita Hidetoshi; Fukamizu Akiyoshi; Nishioka Kusuki; Nakajima Toshihiro
TNFalpha induces acetylation of p53 but attenuates its transcriptional activation in rheumatoid synoviocytes.
International journal of molecular medicine 2002;10(3):269-75.
2002: Kang Ningling; Walther Thomas; Tian Xiao-Li; Bohlender Jürgen; Fukamizu Akiyoshi; Ganten Detlev; Bader Michael
Reduced hypertension-induced end-organ damage in mice lacking cardiac and renal angiotensinogen synthesis.
Journal of molecular medicine (Berlin, Germany) 2002;80(6):359-66.
2002: Takahashi Yoshinori; Kako Koichiro; Arai Hidenori; Ohishi Takahiro; Inada Yoshiko; Takehara Akio; Fukamizu Akiyoshi; Munekata Eisuke
Characterization and identification of promoter elements in the mouse COX17 gene.
Biochimica et biophysica acta 2002;1574(3):359-64.
2002: Saitoh Masayuki; Takayanagi Ryoichi; Goto Kiminobu; Fukamizu Akiyoshi; Tomura Arihiro; Yanase Toshihiko; Nawata Hajime
The presence of both the amino- and carboxyl-terminal domains in the AR is essential for the completion of a transcriptionally active form with coactivators and intranuclear compartmentalization common to the steroid hormone receptors: a three-dimensional imaging study.
Molecular endocrinology (Baltimore, Md.) 2002;16(4):694-706.
2002: Kawabata Hisashi; Kawahara Ko-ichi; Kanekura Takuro; Araya Natsumi; Daitoku Hiroaki; Hatta Mitsutoki; Miura Naoki; Fukamizu Akiyoshi; Kanzaki Tamotsu; Maruyama Ikuro; Nakajima Toshihiro
Possible role of transcriptional coactivator P/CAF and nuclear acetylation in calcium-induced keratinocyte differentiation.
The Journal of biological chemistry 2002;277(10):8099-105.
2002: Hatta Mitsutoki; Daitoku Hiroaki; Matsuzaki Hitomi; Deyama Yoshiaki; Yoshimura Yoshitaka; Suzuki Kuniaki; Matsumoto Akira; Fukamizu Akiyoshi
Regulation of alkaline phosphatase promoter activity by forkhead transcription factor FKHR.
International journal of molecular medicine 2002;9(2):147-52.
2001: Takanami-Ohnishi Y; Asada S; Tsunoda H; Fukamizu A; Goto K; Yoshikawa H; Kubo T; Sudo T; Kimura S; Kasuya Y
Possible involvement of p38 mitogen-activated protein kinase in decidual function in parturition.
Biochemical and biophysical research communications 2001;288(5):1155-61.
2001: Yamamoto N; Yamamoto S; Inagaki F; Kawaichi M; Fukamizu A; Kishi N; Matsuno K; Nakamura K; Weinmaster G; Okano H; Nakafuku M
Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor.
The Journal of biological chemistry 2001;276(48):45031-40.
2001: Katoh Y; Itoh K; Yoshida E; Miyagishi M; Fukamizu A; Yamamoto M
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(10):857-68.
2001: Daitoku H; Isida J; Fujiwara K; Nakajima T; Fukamizu A
Dimerization of small GTPase Rab5.
International journal of molecular medicine 2001;8(4):397-404.
2001: Aratani S; Fujii R; Oishi T; Fujita H; Amano T; Ohshima T; Hagiwara M; Fukamizu A; Nakajima T
Dual roles of RNA helicase A in CREB-dependent transcription.
Molecular and cellular biology 2001;21(14):4460-9.
2001: Zhou J; Moroi K; Nishiyama M; Usui H; Seki N; Ishida J; Fukamizu A; Kimura S
Characterization of RGS5 in regulation of G protein-coupled receptor signaling.
Life sciences 2001;68(13):1457-69.
2001: Fujii R; Okamoto M; Aratani S; Oishi T; Ohshima T; Taira K; Baba M; Fukamizu A; Nakajima T
A Role of RNA Helicase A in cis-Acting Transactivation Response Element-mediated Transcriptional Regulation of Human Immunodeficiency Virus Type 1.
The Journal of biological chemistry 2001;276(8):5445-51.
2001: Ohshima T; Yoshida E; Nakajima T; Yagami K I; Fukamizu A
Effects of interaction between parvovirus minute virus of mice NS1 and coactivator CBP on NS1- and p53-transactivation.
International journal of molecular medicine 2001;7(1):49-54.
2001: Nakazawa M; Ishii H; Nakamura H; Yoshino S I; Fukamizu A; Nishioka K; Nakajima T
NFkappaB2 (p52) promoter activation via Notch signaling pathway in rheumatoid synoviocytes.
International journal of molecular medicine 2001;7(1):31-5.
2000: Kashiwabara S; Zhuang T; Yamagata K; Noguchi J; Fukamizu A; Baba T
Identification of a novel isoform of poly(A) polymerase, TPAP, specifically present in the cytoplasm of spermatogenic cells.
Developmental biology 2000;228(1):106-15.
2000: Fukamizu A
Genomic expression systems on hierarchy and network leading to hypertension: long on history, short on facts.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(6):545-52.
2000: Miyagishi M; Fujii R; Hatta M; Yoshida E; Araya N; Nagafuchi A; Ishihara S; Nakajima T; Fukamizu A
Regulation of Lef-mediated transcription and p53-dependent pathway by associating beta-catenin with CBP/p300.
The Journal of biological chemistry 2000;275(45):35170-5.
2000: Usui H; Nishiyama M; Moroi K; Shibasaki T; Zhou J; Ishida J; Fukamizu A; Haga T; Sekiya S; Kimura S
RGS domain in the amino-terminus of G protein-coupled receptor kinase 2 inhibits Gq-mediated signaling.
International journal of molecular medicine 2000;5(4):335-40.
2000: Sugiyama F; Yagami K; Fukamizu A
[Transgenic models for human hypertension]
Nippon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 2():721-4.
2000: Yanai K; Saito T; Kakinuma Y; Kon Y; Hirota K; Taniguchi-Yanai K; Nishijo N; Shigematsu Y; Horiguchi H; Kasuya Y; Sugiyama F; Yagami K i; Murakami K; Fukamizu A
Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice.
The Journal of biological chemistry 2000;275(1):5-8.
2000: Miyagishi M; Nakajima T; Fukamizu A
Molecular characterization of mesoderm-restricted basic helix-loop-helix protein, POD-1/Capsulin.
International journal of molecular medicine 2000;5(1):27-31.
1999: Kawahara K; Watanabe S; Ohshima T; Soejima Y; Oishi T; Aratani S; Nakata M; Shibata M; Inoue K; Amano T; Fujii R; Yanai K; Hagiwara M; Fukamizu A; Maruyama I; Nakajima T
Hypernuclear acetylation in atherosclerotic lesions and activated vascular smooth muscle cells.
Biochemical and biophysical research communications 1999;266(2):417-24.
1999: Yanai K; Hirota K; Taniguchi-Yanai K; Shigematsu Y; Shimamoto Y; Saito T; Chowdhury S; Takiguchi M; Arakawa M; Nibu Y; Sugiyama F; Yagami K; Fukamizu A
Regulated expression of human angiotensinogen gene by hepatocyte nuclear factor 4 and chicken ovalbumin upstream promoter-transcription factor.
The Journal of biological chemistry 1999;274(49):34605-12.
1999: Mochizuki R; Ishizuka Y; Yanai K; Koga Y; Fukamizu A; Murakami K
Molecular cloning and expression of human neurochondrin-1 and -2.
Biochimica et biophysica acta 1999;1446(3):397-402.
1999: Nishijo N; Takamine S; Sugiyama F; Kimoto K; Taniguchi K; Horiguchi H; Ogata T; Murakami K; Fukamizu A; Yagami K
Vascular remodeling in hypertensive transgenic mice.
Experimental animals / Japanese Association for Laboratory Animal Science 1999;48(3):203-8.
1999: Fukamizu A
[Angiotensin and arteriosclerosis: an approach from transgenic and knockout mice]
Nippon rinsho. Japanese journal of clinical medicine 1999;57(5):1176-81.
1999: Ishida J; Fukamizu A
[Angiotensin II and apoptosis]
Nippon rinsho. Japanese journal of clinical medicine 1999;57(5):1117-23.
1999: Ishiduka Y; Mochizuki R; Yanai K; Takatsuka M; Nonomura T; Niida S; Horiguchi H; Maeda N; Fukamizu A
Induction of hydroxyapatite resorptive activity in bone marrow cell populations resistant to bafilomycin A1 by a factor with restricted expression to bone and brain, neurochondrin.
Biochimica et biophysica acta 1999;1450(1):92-8.
1999: Ishida J; Asada S; Daitoku H; Fujiwara K; Kon Y; Sugaya T; Murakami K; Nakajima T; Kasuya Y; Fukamizu A
Expression and characterization of mouse angiotensin II type 1a receptor tagging hemagglutinin epitope in cultured cells.
International journal of molecular medicine 1999;3(3):263-70.
1998: Ishida J; Sugiyama F; Tanimoto K; Taniguchi K; Syouji M; Takimoto E; Horiguchi H; Murakami K; Yagami K i; Fukamizu A
Rescue of angiotensinogen-knockout mice.
Biochemical and biophysical research communications 1998;252(3):610-6.
1998: Nishijo N; Sugiyama F; Kimoto K; Taniguchi K; Murakami K; Suzuki S; Fukamizu A; Yagami K
Salt-sensitive aortic aneurysm and rupture in hypertensive transgenic mice that overproduce angiotensin II.
Laboratory investigation; a journal of technical methods and pathology 1998;78(9):1059-66.
1998: Tamura K; Umemura S; Sumida Y; Nyui N; Kobayashi S; Ishigami T; Kihara M; Sugaya T; Fukamizu A; Miyazaki H; Murakami K; Ishii M
Effect of genetic deficiency of angiotensinogen on the renin-angiotensin system.
Hypertension 1998;32(2):223-7.
1998: Tamura K; Umemura S; Nyui N; Yabana M; Toya Y; Fukamizu A; Murakami K; Ishii M
Possible role of c-Jun in transcription of the mouse renin gene.
Kidney international 1998;54(2):382-93.
1998: Shiota N; Fukamizu A; Okunishi H; Takai S; Murakami K; Miyazaki M
Cloning of the gene and cDNA for hamster chymase 2, and expression of chymase 1, chymase 2 and angiotensin-converting enzyme in the terminal stage of cardiomyopathic hearts.
The Biochemical journal 1998;333 ( Pt 2)():417-24.
1998: Kihara M; Umemura S; Sugaya T; Toya Y; Yabana M; Kobayashi S; Tamura K; Kadota T; Kishida R; Murakami K; Fukamizu A; Ishii M
Expression of neuronal type nitric oxide synthase and renin in the juxtaglomerular apparatus of angiotensin type-1a receptor gene-knockout mice.
Kidney international 1998;53(6):1585-93.
1998: Taniguchi K; Sugiyama F; Kakinuma Y; Uehara S; Nishijho N; Tanimoto K; Murakami K; Fukamizu A; Yagami K I
Pathologic characterization of hypotensive C57BL/6J-agt: angiotensinogen-deficient C57BL/6J mice.
International journal of molecular medicine 1998;1(3):583-7.
1998: Umemura S; Kihara M; Sumida Y; Yabana M; Ishigami T; Tamura K; Nyui N; Hibi K; Murakami K; Fukamizu A; Ishii M
Endocrinological abnormalities in angiotensinogen-gene knockout mice: studies of hormonal responses to dietary salt loading.
Journal of hypertension 1998;16(3):285-9.
1998: Kihara M; Umemura S; Yabana M; Sumida Y; Nyui N; Tamura K; Kadota T; Kishida R; Murakami K; Fukamizu A; Ishii M
Dietary salt loading decreases the expressions of neuronal-type nitric oxide synthase and renin in the juxtaglomerular apparatus of angiotensinogen gene-knockout mice.
Journal of the American Society of Nephrology : JASN 1998;9(3):355-62.
1998: Kihara M; Umemura S; Sumida Y; Yokoyama N; Yabana M; Nyui N; Tamura K; Murakami K; Fukamizu A; Ishii M
Genetic deficiency of angiotensinogen produces an impaired urine concentrating ability in mice.
Kidney international 1998;53(3):548-55.
1998: Yoshida E; Tanimoto K; Murakami K; Fukamizu A
Isolation and characterization of 5'-regulatory region of mouse activin beta A subunit gene.
Biochemistry and molecular biology international 1998;44(2):325-32.
1998: Yoshida E; Nakajima T; Murakami K; Fukamizu A
Identification of N-terminal minimal transactivation domain of CBP, p300 and caenorhabditis elegans homologues.
Gene 1998;208(2):307-14.
1998: Sumida Y; Umemura S; Tamura K; Kihara M; Kobayashi S; Ishigami T; Yabana M; Nyui N; Ochiai H; Fukamizu A; Miyazaki H; Murakami K; Ishii M
Increased cardiac angiotensin II receptors in angiotensinogen-deficient mice.
Hypertension 1998;31(1):45-9.
1997: Yoshida E; Aratani S; Itou H; Miyagishi M; Takiguchi M; Osumu T; Murakami K; Fukamizu A
Functional association between CBP and HNF4 in trans-activation.
Biochemical and biophysical research communications 1997;241(3):664-9.
1997: Fukamizu A
[Genetic dissection of protease and signal transduction network]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(14 Suppl):2441-7.
1997: Sugiyama F; Tanimoto Y; Kato H; Nomura T; Taniguchi K; Tanimoto K; Murakami K; Fukamizu A; Yagami K
Speedy backcrossing through in vitro fertilization, using pre-pubertal superovulation and neonatal death dependent on genetic background in angiotensinogen-deficient mice.
Laboratory animal science 1997;47(5):545-8.
1997: Fukamizu A
[Molecular biology and genetics of angiotensin signal-transduction system]
Seikagaku. The Journal of Japanese Biochemical Society 1997;69(8):991-1002.
1997: Sugiyama F; Taniguchi K; Fukamizu A; Yagami K
[Genetically engineered mice for study of human hypertension]
Nippon rinsho. Japanese journal of clinical medicine 1997;55(8):2005-10.
1997: Yanai K; Murakami K; Fukamizu A
ATF-like element contributes to hepatic activation of human angiotensinogen promoter.
Biochemical and biophysical research communications 1997;237(1):158-62.
1997: Yanai K; Matsuyama S; Murakami K; Fukamizu A
Differential action of AGCF2 upon cell type-dependent expression of human angiotensinogen gene.
FEBS letters 1997;412(2):285-9.
1997: Tamura K; Umemura S; Nyui N; Yamaguchi S; Ishigami T; Hibi K; Yabana M; Kihara M; Fukamizu A; Murakami K; Ishii M
A novel proximal element mediates the regulation of mouse Ren-1C promoter by retinoblastoma protein in cultured cells.
The Journal of biological chemistry 1997;272(27):16845-51.
1997: Nyui N; Tamura K; Mizuno K; Ishigami T; Hibi K; Yabana M; Kihara M; Fukamizu A; Ochiai H; Umemura S; Murakami K; Ohno S; Ishii M
Stretch-induced MAP kinase activation in cardiomyocytes of angiotensinogen-deficient mice.
Biochemical and biophysical research communications 1997;235(1):36-41.
1997: Sugiyama F; Haraoka S; Watanabe T; Shiota N; Taniguchi K; Ueno Y; Tanimoto K; Murakami K; Fukamizu A; Yagami K
Acceleration of atherosclerotic lesions in transgenic mice with hypertension by the activated renin-angiotensin system.
Laboratory investigation; a journal of technical methods and pathology 1997;76(6):835-42.
1997: Shiota N; Fukamizu A; Takai S; Okunishi H; Murakami K; Miyazaki M
Activation of angiotensin II-forming chymase in the cardiomyopathic hamster heart.
Journal of hypertension 1997;15(4):431-40.
1997: Fukamizu A; Murakami K
Activated and inactivated renin-angiotensin system in transgenic animals: from genes to blood pressure.
Laboratory animal science 1997;47(2):127-31.
1997: Kihara M; Umemura S; Kadota T; Yabana M; Tamura K; Nyuui N; Ogawa N; Murakami K; Fukamizu A; Ishii M
The neuronal isoform of constitutive nitric oxide synthase is up-regulated in the macula densa of angiotensinogen gene-knockout mice.
Laboratory investigation; a journal of technical methods and pathology 1997;76(2):285-94.
1997: Bohlender J; Fukamizu A; Lippoldt A; Nomura T; Dietz R; Ménard J; Murakami K; Luft F C; Ganten D
High human renin hypertension in transgenic rats.
Hypertension 1997;29(1 Pt 2):428-34.
1996: Tanimoto K; Yoshida E; Mita S; Nibu Y; Murakami K; Fukamizu A
Human activin betaA gene. Identification of novel 5' exon, functional promoter, and enhancers.
The Journal of biological chemistry 1996;271(51):32760-9.
1996: Nagata M; Tanimoto K; Fukamizu A; Kon Y; Sugiyama F; Yagami K; Murakami K; Watanabe T
Nephrogenesis and renovascular development in angiotensinogen-deficient mice.
Laboratory investigation; a journal of technical methods and pathology 1996;75(5):745-53.
1996: Takimoto E; Ishida J; Sugiyama F; Horiguchi H; Murakami K; Fukamizu A
Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen.
Science (New York, N.Y.) 1996;274(5289):995-8.
1995: Goto Y; Sugiyama F; Tanimoto K; Ishida J; Syoji M; Takahashi A; Sugiyama Y; Murakami K; Fukamizu A; Yagami K
Evaluation of coculture aggregation with TT2 cells for production of germline chimera.
Laboratory animal science 1995;45(5):601-3.
1995: Sugiyama F; Sagara M; Matsuda Y; Horiguchi H; Kamma H; Ogata T; Hatae T; Yagami K; Murakami K; Fukamizu A
Heritable formation of neuroectodermal tumor in transgenic mice carrying the combined E1 region gene of adenovirus type 12 with the deregulated human renin promoter.
Journal of cellular biochemistry 1995;57(4):691-700.
1995: Tamura K; Umemura S; Fukamizu A; Ishii M; Murakami K
Recent advances in the study of renin and angiotensinogen genes: from molecules to the whole body.
Hypertension research : official journal of the Japanese Society of Hypertension 1995;18(1):7-18.
1995: Sagara M; Sugiyama F; Horiguchi H; Kamma H; Ogata T; Yagami K; Murakami K; Fukamizu A
Activation of the nuclear oncogenes N-myc and c-jun in carcinoid [correction of cartinoid] tumors of transgenic mice carrying the human adenovirus type 12 E1 region gene.
DNA and cell biology 1995;14(2):95-101.
1994: Tanimoto K; Sugiyama F; Goto Y; Ishida J; Takimoto E; Yagami K; Fukamizu A; Murakami K
Angiotensinogen-deficient mice with hypotension.
The Journal of biological chemistry 1994;269(50):31334-7.
1994: Fukamizu A; Sagara M; Sugiyama F; Horiguchi H; Kamma H; Hatae T; Ogata T; Yagami K; Murakami K
Neuroectodermal tumors expressing c-, L-, and N-myc in transgenic mice that carry the E1A/E1B gene of human adenovirus type 12.
The Journal of biological chemistry 1994;269(49):31252-8.
1994: Nibu Y; Tanimoto K; Takahashi S; Ono H; Murakami K; Fukamizu A
A cell type-dependent enhancer core element is located in exon 5 of the human angiotensinogen gene.
Biochemical and biophysical research communications 1994;205(2):1102-8.
1994: Fukamizu A; Watanabe M; Inoue Y; Kon Y; Shimada S; Shiota N; Sugiyama F; Murakami K
Cortical expression of the human angiotensinogen gene in the kidney of transgenic mice.
Kidney international 1994;46(6):1533-5.
1994: Nibu Y; Takahashi S; Tanimoto K; Murakami K; Fukamizu A
Identification of cell type-dependent enhancer core element located in the 3'-downstream region of the human angiotensinogen gene.
The Journal of biological chemistry 1994;269(46):28598-605.
1994: Tomura D; Obika K; Fukamizu A; Shoun H
Nitric oxide reductase cytochrome P-450 gene, CYP 55, of the fungus Fusarium oxysporum containing a potential binding-site for FNR, the transcription factor involved in the regulation of anaerobic growth of Escherichia coli.
Journal of biochemistry 1994;116(1):88-94.
1994: Tamura K; Umemura S; Ishii M; Tanimoto K; Murakami K; Fukamizu A
Molecular mechanism of transcriptional activation of angiotensinogen gene by proximal promoter.
The Journal of clinical investigation 1994;93(4):1370-9.
1994: Tanimoto K; Murakami K; Fukamizu A
Combinatorial action of cAMP and phorbol ester on synergistic expression of the human activin A gene.
Experimental cell research 1994;211(2):408-14.
1994: Tamura K; Umemura S; Iwamoto T; Yamaguchi S; Kobayashi S; Takeda K; Tokita Y; Takagi N; Murakami K; Fukamizu A
Molecular mechanism of adipogenic activation of the angiotensinogen gene.
Hypertension 1994;23(3):364-8.
1994: Fukamizu A; Uehara S; Hatae T; Tamura K; Watanabe K; Sugiyama F; Murakami K
Species-specific expression of the hepatic renin gene.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1994;56(1):109-14.
1994: Fukamizu A; Sagara M; Sugiyama F; Yagami K; Murakami K
Tissue-specific trans-activation of renin gene by targeted expression of adenovirus E1A in transgenic mice.
Biochemical and biophysical research communications 1994;199(1):183-90.
1994: Hatae T; Takimoto E; Murakami K; Fukamizu A
Comparative studies on species-specific reactivity between renin and angiotensinogen.
Molecular and cellular biochemistry 1994;131(1):43-7.
1993: Obika K; Tomura D; Fukamizu A; Shoun H
Expression of the fungal cytochrome P-450nor cDNA in Escherichia coli.
Biochemical and biophysical research communications 1993;196(3):1255-60.
1993: Tamura K; Tanimoto K; Ishii M; Murakami K; Fukamizu A
Proximal and core DNA elements are required for efficient angiotensinogen promoter activation during adipogenic differentiation.
The Journal of biological chemistry 1993;268(20):15024-32.
1993: Fukamizu A; Sugimura K; Takimoto E; Sugiyama F; Seo M S; Takahashi S; Hatae T; Kajiwara N; Yagami K; Murakami K
Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes.
The Journal of biological chemistry 1993;268(16):11617-21.
1993: Shimada S; Fukamizu A; Murakami K
[Developmental biotechnology and hypertension--emphasis on renin-angiotensin system]
Nippon rinsho. Japanese journal of clinical medicine 1993;51(6):1562-7.
1993: Shiota N; Okunishi H; Fukamizu A; Sakonjo H; Kikumori M; Nishimura T; Nakagawa T; Murakami K; Miyazaki M
Activation of two angiotensin-generating systems in the balloon-injured artery.
FEBS letters 1993;323(3):239-42.
1993: Tanimoto K; Murakami K; Fukamizu A
Possible roles of the 3'-flanking sequences of the human activin beta A subunit gene in its expression.
Archives of biochemistry and biophysics 1993;302(2):409-16.
1993: Tamura K; Tanimoto K; Murakami K; Fukamizu A
Activation of mouse renin promoter by cAMP and c-Jun in a kidney-derived cell line.
Biochimica et biophysica acta 1993;1172(3):306-10.
1993: Fukamizu A; Takimoto E; Sugimura K; Hatae T; Seo M S; Takahashi S; Sugiyama F; Kajiwara N; Yagami K; Murakami K
Dependence of angiotensin production in transgenic mice carrying either the human renin or human angiotensinogen genes on species-specific kinetics of the renin-angiotensin system.
Arzneimittel-Forschung 1993;43(2A):222-5.
1992: Takahashi S; Fukamizu A; Hatae T; Yamada Y; Sugiyama F; Kajiwara N; Yagami K; Murakami K
Species-specific kinetics of mouse renin contribute to maintenance of normal blood pressure in transgenic mice with overexpressed human angiotensinogen.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1992;54(6):1191-3.
1992: Hatae T; Takimoto E; Fukamizu A; Hori H; Kimoto K; Murakami K
Expression and purification of human angiotensinogen in Chinese hamster ovary cells.
Biochimica et biophysica acta 1992;1121(3):335-8.
1992: Takahashi S; Fukamizu A; Sugiyama F; Kajiwara N; Yagami K; Murakami K
Species-specific induction of angiotensinogen mRNA in transgenic mouse liver during acute phase reaction.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1992;54(2):367-9.
1992: Tamura K; Tanimoto K; Takahashi S; Sagara M; Fukamizu A; Murakami K
Structure and expression of the mouse angiotensinogen gene.
Japanese heart journal 1992;33(1):113-24.
1992: Tanimoto K; Tamura K; Ueno N; Usuki S; Murakami K; Fukamizu A
Regulation of activin beta A mRNA level by cAMP.
Biochemical and biophysical research communications 1992;182(2):773-8.
1991: Seo M S; Fukamizu A; Saito T; Murakami K
Identification of a previously unrecognized production site of human renin.
Biochimica et biophysica acta 1991;1129(1):87-9.
1991: Takahashi S; Fukamizu A; Hasegawa T; Yokoyama M; Nomura T; Katsuki M; Murakami K
Expression of the human angiotensinogen gene in transgenic mice and transfected cells.
Biochemical and biophysical research communications 1991;180(2):1103-9.
1991: Kizawa H; Tomura D; Oda M; Fukamizu A; Hoshino T; Gotoh O; Yasui T; Shoun H
Nucleotide sequence of the unique nitrate/nitrite-inducible cytochrome P-450 cDNA from Fusarium oxysporum.
The Journal of biological chemistry 1991;266(16):10632-7.
1991: Fukamizu A; Tanimoto K; Uehara S; Seo M S; Handa S; Sagara M; Takahashi S; Imai T; Murakami K
Regulation of human renin and angiotensinogen genes.
Biomedica biochimica acta 1991;50(4-6):659-63.
1991: Tanimoto K; Handa S; Ueno N; Murakami K; Fukamizu A
Structure and sequence analysis of the human activin beta A subunit gene.
DNA sequence : the journal of DNA sequencing and mapping 1991;2(2):103-10.
1990: Fukamizu A; Takahashi S; Seo M S; Tada M; Tanimoto K; Uehara S; Murakami K
Structure and expression of the human angiotensinogen gene. Identification of a unique and highly active promoter.
The Journal of biological chemistry 1990;265(13):7576-82.
1990: Seo M S; Fukamizu A; Nomura T; Yokoyama M; Katsuki M; Murakami K
The human renin gene in transgenic mice.
Journal of cardiovascular pharmacology 1990;16 Suppl 4():S8-10.
1990: Fukamizu A; Takahashi S; Murakami K
Expression of the human angiotensinogen gene in human cell lines.
Journal of cardiovascular pharmacology 1990;16 Suppl 4():S11-3.
1989: Fukamizu A; Seo M S; Hatae T; Yokoyama M; Nomura T; Katsuki M; Murakami K
Tissue-specific expression of the human renin gene in transgenic mice.
Biochemical and biophysical research communications 1989;165(2):826-32.
1989: Baba T; Kashiwabara S; Watanabe K; Itoh H; Michikawa Y; Kimura K; Takada M; Fukamizu A; Arai Y
Activation and maturation mechanisms of boar acrosin zymogen based on the deduced primary structure.
The Journal of biological chemistry 1989;264(20):11920-7.
1989: Tada M; Fukamizu A; Seo M S; Takahashi S; Murakami K
Renin expression in the kidney and brain is reciprocally controlled by captopril.
Biochemical and biophysical research communications 1989;159(3):1065-71.

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