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Tsutomu Fukuwatari

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Chiaki Hiratsuka; Kuniaki Saito; Mitsue Sano; Satoshi Sasaki; Tsutomu Fukuwatari; Katsumi Shibata
Supplementing Healthy Women with up to 5.0 g/d of L-Tryptophan Has No Adverse Effects.
Eri Imai; Mitsue Sano; Tsutomu Fukuwatari; Katsumi Shibata
Changes in B-group vitamin status in adenine-induced chronic renal failure rats.
Katsumi Shibata; Chisa Sugita; Isao Azumano; Tsutomu Fukuwatari; Saori Higashiyama; Masaaki Onda
Pantothenic acid refeeding diminishes the liver, perinephrical fats, and plasma fats accumulated by pantothenic acid deficiency and/or ethanol consumption.

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2013: Chiaki Hiratsuka; Kuniaki Saito; Mitsue Sano; Satoshi Sasaki; Tsutomu Fukuwatari; Katsumi Shibata
Supplementing Healthy Women with up to 5.0 g/d of L-Tryptophan Has No Adverse Effects.
The Journal of nutrition 2013;143(6):859-66.
2013: Eri Imai; Mitsue Sano; Tsutomu Fukuwatari; Katsumi Shibata
Changes in B-group vitamin status in adenine-induced chronic renal failure rats.
Bioscience, biotechnology, and biochemistry 2013;77(5):1108-10.
2013: Katsumi Shibata; Chisa Sugita; Isao Azumano; Tsutomu Fukuwatari; Saori Higashiyama; Masaaki Onda
Pantothenic acid refeeding diminishes the liver, perinephrical fats, and plasma fats accumulated by pantothenic acid deficiency and/or ethanol consumption.
Nutrition (Burbank, Los Angeles County, Calif.) 2013;29(5):796-801.
2013: Katsumi Shibata; Rina Kondo; Mitsue Sano; Tsutomu Fukuwatari
Increased conversion of tryptophan to nicotinamide in rats by dietary valproate.
Bioscience, biotechnology, and biochemistry 2013;77(2):295-300.
2012: Miki Terakata; Shin-Ichi Fukuoka; Tsutomu Fukuwatari; Natsuki Nakao; Mitsue Sano; Ryuzo Sasaki; Katsumi Shibata
Establishment of true niacin deficiency in quinolinic acid phosphoribosyltransferase knockout mice.
The Journal of nutrition 2012;142(12):2148-53.
2012: Katsumi Shibata; Tsutomu Fukuwatari
The metabolites in the tryptophan degradation pathway might be useful to determine the tolerable upper intake level of tryptophan intake in rats.
The Journal of nutrition 2012;142(12):2227S-2230S.
2012: Katsumi Shibata; Takumi Nakai; Tsutomu Fukuwatari
Simultaneous high-performance liquid chromatography determination of coenzyme A, dephospho-coenzyme A, and acetyl-coenzyme A in normal and pantothenic acid-deficient rats.
Analytical biochemistry 2012;430(2):151-5.
2012: Aiko Miyazaki; Mitsue Sano; Tsutomu Fukuwatari; Katsumi Shibata
Effects of ethanol consumption on the B-group vitamin contents of liver, blood and urine in rats.
The British journal of nutrition 2012;108(6):1034-41.
2012: Chiaki Hiratsuka; Tsutomu Fukuwatari; Katsumi Shibata
Fate of dietary tryptophan in young Japanese women.
International journal of tryptophan research : IJTR 2012;5():33-47.
2012: Eri Imai; Mitsue Sano; Tsutomu Fukuwatari; Katsumi Shibata
Urinary excretion of water-soluble vitamins increases in streptozotocin-induced diabetic rats without decreases in liver or blood vitamin content.
Journal of nutritional science and vitaminology 2012;58(1):54-8.
2012: Katsumi Shibata; Eri Imai; Mitsue Sano; Tsutomu Fukuwatari
The urinary excretory ratio of nicotinamide catabolites was associated with the conversion ratio of tryptophan to nicotinamide in growing rats fed a niacin-free 20% casein diet.
Bioscience, biotechnology, and biochemistry 2012;76(1):186-8.
2011: Alato Okuno; Tsutomu Fukuwatari; Katsumi Shibata
High tryptophan diet reduces extracellular dopamine release via kynurenic acid production in rat striatum.
Journal of neurochemistry 2011;118(5):796-805.
2011: Eri Imai; Mitsue Sano; Tsutomu Fukuwatari; Tomiko Tsuji; Katsumi Shibata
Association between 24 hour urinary α-tocopherol catabolite, 2,5,7,8-tetramethyl-2(2'-carboxyethyl)-6-hydroxychroman (α-CEHC) and α-tocopherol intake in intervention and cross-sectional studies.
Asia Pacific journal of clinical nutrition 2011;20(4):507-13.
2011: Mika Endo; Tsutomu Fukuwatari; Mitsue Sano; Katsumi Shibata
Vitamin contents in rat milk and effects of dietary vitamin intakes of dams on the vitamin contents in their milk.
Journal of nutritional science and vitaminology 2011;57(3):203-8.
2011: Katsumi Shibata; Miki Yasui; Mitsue Sano; Tsutomu Fukuwatari
Fluorometric determination of 2-oxoadipic acid, a common metabolite of tryptophan and lysine, by high-performance liquid chromatography with pre-chemical derivatization.
Bioscience, biotechnology, and biochemistry 2011;75(1):185-7.
2010: Erina Yoshida; Tsutomu Fukuwatari; Masako Ohtsubo; Katsumi Shibata
High-fat diet lowers the nutritional status indicators of pantothenic acid in weaning rats.
Bioscience, biotechnology, and biochemistry 2010;74(8):1691-3.
2010: Tsutomu Fukuwatari; Erina Yoshida; Kei Takahashi; Katsumi Shibata
Effect of fasting on the urinary excretion of water-soluble vitamins in humans and rats.
Journal of nutritional science and vitaminology 2010;56(1):19-26.
2009: Katsumi Shibata; Tsutomu Fukuwatari; Toshiaki Watanabe; Mamoru Nishimuta
Intra- and inter-individual variations of blood and urinary water-soluble vitamins in Japanese young adults consuming a semi-purified diet for 7 days.
Journal of nutritional science and vitaminology 2009;55(6):459-70.
2009: Tsutomu Fukuwatari; Ema Sugimoto; Tomiko Tsuji; Junko Hirose; Tomiho Fukui; Katsumi Shibata
Urinary excretion of vitamin B12 depends on urine volume in Japanese female university students and elderly.
Nutrition research (New York, N.Y.) 2009;29(12):839-45.
2009: Stephen J D O'Keefe; Junhai Ou; Susanne Aufreiter; Deborah O'Connor; Sumit Sharma; Jorge Sepulveda; Tsutomu Fukuwatari; Katsumi Shibata; Thomas Mawhinney
Products of the colonic microbiota mediate the effects of diet on colon cancer risk.
The Journal of nutrition 2009;139(11):2044-8.
2009: Kei Takahashi; Tsutomu Fukuwatari; Katsumi Shibata
Fluorometric determination of pantothenic acid in human urine by isocratic reversed-phase ion-pair high-performance liquid chromatography with post-column derivatization.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(22):2168-72.
2009: Tsutomu Fukuwatari; Katsumi Shibata
Consideration of diurnal variations in human blood NAD and NADP concentrations.
Journal of nutritional science and vitaminology 2009;55(3):279-81.
2009: Tsutomu Fukuwatari; Kaori Kurata; Katsumi Shibata
[Effects of excess nicotinic acid on growth and the urinary excretion of B-group vitamins and the metabolism of tryptophan in weaning rats].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2009;50(2):80-4.
2009: Tsutomu Fukuwatari; Keiko Itoh; Katsumi Shibata
[Effects of excess pyridoxine-HCl on growth and urinary excretion of water-soluble vitamins in weaning rats].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2009;50(2):75-9.
2009: Tsutomu Fukuwatari; Mako Kuzuya; Shiori Satoh; Katsumi Shibata
[Effects of excess vitamin B1 or vitamin B2 on growth and urinary excretion of water-soluble vitamins in weaning rats].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2009;50(2):70-4.
2009: Kei Takahashi; Alato Okuno; Tsutomu Fukuwatari; Katsumi Shibata
Comparison of the nicotinamide catabolism among rat strains.
Bioscience, biotechnology, and biochemistry 2009;73(2):274-9.
2009: Tsutomu Fukuwatari; Mio Fujita; Katsumi Shibata
Effects of UVA irradiation on the concentration of folate in human blood.
Bioscience, biotechnology, and biochemistry 2009;73(2):322-7.
2008: Tsutomu Fukuwatari; Hideko Wada; Katsumi Shibata
Age-related alterations of B-group vitamin contents in urine, blood and liver from rats.
Journal of nutritional science and vitaminology 2008;54(5):357-62.
2008: Tsutomu Fukuwatari; Katsumi Shibata
The formation of nicotinamide by administration of di(2-ethylhexyl)phthalate does not cause growth retardation in young rats in contrast with excess exogenous administration of nicotinamide.
Bioscience, biotechnology, and biochemistry 2008;72(9):2423-7.
2008: Munehiro Yoshida; Akiko Takada; Junko Hirose; Mika Endô; Tsutomu Fukuwatari; Katsumi Shibata
Molybdenum and chromium concentrations in breast milk from Japanese women.
Bioscience, biotechnology, and biochemistry 2008;72(8):2247-50.
2008: Alato Okuno; Tsutomu Fukuwatari; Katsumi Shibata
Urinary excretory ratio of anthranilic acid/kynurenic acid as an index of the tolerable amount of tryptophan.
Bioscience, biotechnology, and biochemistry 2008;72(7):1667-72.
2008: Tsutomu Fukuwatari; Katsumi Shibata
Urinary water-soluble vitamins and their metabolite contents as nutritional markers for evaluating vitamin intakes in young Japanese women.
Journal of nutritional science and vitaminology 2008;54(3):223-9.
2008: Tsutomu Fukuwatari; Katsumi Shibata
[Effects of excess folic acid on growth and metabolism of water-soluble vitamins in weaning rats].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2008;49(1):51-5.
2007: Hiromi Sawamura; Tsutomu Fukuwatari; Katsumi Shibata
Effects of excess biotin administration on the growth and urinary excretion of water-soluble vitamins in young rats.
Bioscience, biotechnology, and biochemistry 2007;71(12):2977-84.
2007: Tsutomu Fukuwatari; Katsumi Shibata
Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 2007;77(4):255-62.
2006: Katsumi Shibata; Tsutomu Fukuwatari; Yoriko Iguchi; Yuko Kurata; Miki Sudo; Ryuzo Sasaki
Comparison of the effects of di(2-ethylhexyl)phthalate, a peroxisome proliferator, on the vitamin metabolism involved in the energy formation in rats fed with a casein or gluten diet.
Bioscience, biotechnology, and biochemistry 2006;70(6):1331-7.
2006: Naoko Kimura; Tsutomu Fukuwatari; Ryuzo Sasaki; Katsumi Shibata
Comparison of metabolic fates of nicotinamide, NAD+ and NADH administered orally and intraperitoneally; characterization of oral NADH.
Journal of nutritional science and vitaminology 2006;52(2):142-8.
2005: Katsumi Shibata; Chisato Takahashi; Tsutomu Fukuwatari; Ryuzo Sasaki
Effects of excess pantothenic acid administration on the other water-soluble vitamin metabolisms in rats.
Journal of nutritional science and vitaminology 2005;51(6):385-91.
2005: Katsumi Shibata; Tsutomu Fukuwatari; Mari Ohta; Hidemi Okamoto; Toshiaki Watanabe; Tooru Fukui; Mamoru Nishimuta; Masayuki Totani; Mieko Kimura; Nobuko Ohishi; Mieko Nakashima; Fumio Watanabe; Emi Miyamoto; Shigeru Shigeoka; Tooru Takeda; Megumi Murakami; Hiroshi Ihara; Naotaka Hashizume
Values of water-soluble vitamins in blood and urine of Japanese young men and women consuming a semi-purified diet based on the Japanese Dietary Reference Intakes.
Journal of nutritional science and vitaminology 2005;51(5):319-28.
2005: Naoko Kimura; Tsutomu Fukuwatari; Ryuzo Sasaki; Katsumi Shibata
The necessity of niacin in rats fed on a high protein diet.
Bioscience, biotechnology, and biochemistry 2005;69(2):273-9.
2004: Tsutomu Fukuwatari; Mari Ohta; Naoko Kimtjra; Ryuzo Sasaki; Katsumi Shibata
Conversion ratio of tryptophan to niacin in Japanese women fed a purified diet conforming to the Japanese Dietary Reference Intakes.
Journal of nutritional science and vitaminology 2004;50(6):385-91.
2004: Tsutomu Fukuwatari; Chie Suzuura; Ryuzo Sasaki; Katsumi Shibata
[Action site of bisphenol A as metabolic disruptor lies in the tryptophan-nicotinamide conversion pathway].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2004;45(5):231-8.
2004: Tsutomu Fukuwatari; Seiko Ohsaki; Shin-Ichi Fukuoka; Ryuzo Sasaki; Katsumi Shibata
Phthalate esters enhance quinolinate production by inhibiting alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of the tryptophan pathway.
Toxicological sciences : an official journal of the Society of Toxicology 2004;81(2):302-8.
2004: Tsutomu Fukuwatari; Mari Ohta; Etsuro Sugimoto; Ryuzo Sasaki; Katsumi Shibata
Effects of dietary di(2-ethylhexyl)phthalate, a putative endocrine disrupter, on enzyme activities involved in the metabolism of tryptophan to niacin in rats.
Biochimica et biophysica acta 2004;1672(2):67-75.
2004: Yutaka Takahashi; Araki Tanaka; Tsukasa Nakamura; Tsutomu Fukuwatari; Katsumi Shibata; Noriaki Shimada; Isao Ebihara; Hikaru Koide
Nicotinamide suppresses hyperphosphatemia in hemodialysis patients.
Kidney international 2004;65(3):1099-104.
2004: Tsutomu Fukuwatari; Mai Toriochi; Mari Ohta; Ryuzo Sasaki; Katsumi Shibata
[Metabolic disturbance of tryptophan-nicotinamide conversion pathway by putative endocrine disruptors, bisphenol A and styrene monomer].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2004;45(1):1-7.
2004: Mari Ohta; Junko Kitamura; Tsutomu Fukuwatari; Ryuzo Sasaki; Katsumi Shibata
Effects of dietary di(2-ethylhexyl)phthalate on the metabolism of tryptophan to niacin in mice.
Experimental animals / Japanese Association for Laboratory Animal Science 2004;53(1):57-60.
2004: Tsutomu Fukuwatari; Hideko Wada; Ryuzo Sasaki; Katsumi Shibata
Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats.
Bioscience, biotechnology, and biochemistry 2004;68(1):44-50.
2003: Takenori Hiraoka; Tsutomu Fukuwatari; Masahiro Imaizumi; Tohru Fushiki
Effects of oral stimulation with fats on the cephalic phase of pancreatic enzyme secretion in esophagostomized rats.
Physiology & behavior 2003;79(4-5):713-7.
2003: Naoko Kimura; Tsutomu Fukuwatari; Ryuzo Sasaki; Fumiko Hayakawa; Katsumi Shibata
Vitamin intake in Japanese women college students.
Journal of nutritional science and vitaminology 2003;49(3):149-55.
2003: Tsutomu Fukuwatari; Katsumi Shibata; Kaori Iguchi; Tomoko Saeki; Akiko Iwata; Kaori Tani; Etsuro Sugimoto; Tohru Fushiki
Role of gustation in the recognition of oleate and triolein in anosmic rats.
Physiology & behavior 2003;78(4-5):579-83.
2003: Hidemi Okamoto; Aya Ishikawa; Yutaka Yoshitake; Naoko Kodama; Mamoru Nishimuta; Tsutomu Fukuwatari; Katsumi Shibata
Diurnal variations in human urinary excretion of nicotinamide catabolites: effects of stress on the metabolism of nicotinamide.
The American journal of clinical nutrition 2003;77(2):406-10.
2003: Tsutomu Fukuwatari; Seiko Ohsaki; Yuko Suzuki; Shin-Ichi Fukuoka; Ryuzo Sasaki; Katsumi Shibata
The effects of phthalate esters on the tryptophan-niacin metabolism.
Advances in experimental medicine and biology 2003;527():659-64.
2003: Shin-Ichi Fukuoka; Kanako Ishiguro; Atsushi Tanabe; Yukari Egashira; Hiroo Sanada; Tsutomu Fukuwatari; Katsumi Shibata
Identification and expression of alpha cDNA encoding human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD): a key enzyme for the tryptophan-niacine pathway and quinolinate hypothesis.
Advances in experimental medicine and biology 2003;527():443-53.
2003: Katsumi Shibata; Tsutomu Fukuwatari; Mayumi Murakami; Ryuzo Sasaki
Increase in conversion of tryptophan to niacin in pregnant rats.
Advances in experimental medicine and biology 2003;527():435-41.
2002: Tsutomu Fukuwatari; Yuko Suzuki; Etsuro Sugimoto; Katsumi Shibata
Identification of a toxic mechanism of the plasticizers, phtahlic acid esters, which are putative endocrine disrupters: time-dependent increase in quinolinic acid and its metabolites in rats fed di(2-ethylhexyl)phthalate.
Bioscience, biotechnology, and biochemistry 2002;66(12):2687-91.
2002: Hidemi Okamoto; Aya Ishikawa; Mamoru Nishimuta; Naoko Kodama; Yutaka Yoshitake; Tsutomu Fukuwatari; Katsumi Shibata
Effects of stress on the urinary excretory pattern of niacin catabolites, the most reliable index of niacin status, in humans.
Journal of nutritional science and vitaminology 2002;48(5):417-9.
2002: Tsutomu Fukuwatari; Etsuro Sugimoto; Katsumi Shibata
Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity.
Bioscience, biotechnology, and biochemistry 2002;66(7):1435-41.
2002: Tsutomu Fukuwatari; Yuko Morikawa; Etsuro Sugimoto; Katsumi Shibata
Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.
Bioscience, biotechnology, and biochemistry 2002;66(6):1196-204.
2002: Tsutomu Fukuwatari; Yuko Suzuki; Etsuro Sugimoto; Katsumi Shibata
Elucidation of the toxic mechanism of the plasticizers, phthalic acid esters, putative endocrine disrupters: effects of dietary di(2-ethylhexyl)phthalate on the metabolism of tryptophan to niacin in rats.
Bioscience, biotechnology, and biochemistry 2002;66(4):705-10.
2001: Tsutomu Fukuwatari; M Doi; Etsuro Sugimoto; T Kawada; Katsumi Shibata
Changes of pyridine nucleotide levels during adipocyte differentiation of mouse 3T3-L1 cells.
Bioscience, biotechnology, and biochemistry 2001;65(11):2565-8.
2001: Tsutomu Fukuwatari; Y Morikawa; F Hayakawa; Etsuro Sugimoto; Katsumi Shibata
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats.
Bioscience, biotechnology, and biochemistry 2001;65(10):2154-61.
2001: Tsutomu Fukuwatari; Etsuro Sugimoto; Katsumi Shibata
[Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2001;42(3):190-6.
2001: Tsutomu Fukuwatari; Etsuro Sugimoto; K Yokoyama; Katsumi Shibata
[Establishment of animal model for elucidating the mechanism of intoxication by the poisonous mushroom Clitocybe acromelalga].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2001;42(3):185-9.
2001: K Shibata; Tsutomu Fukuwatari; A Enomoto; Etsuro Sugimoto
Increased conversion ratio of tryptophan to niacin by dietary di-n-butylphthalate.
Journal of nutritional science and vitaminology 2001;47(3):263-6.
2001: Katsumi Shibata; Tsutomu Fukuwatari; S Zushi; Etsuro Sugimoto
Effect of dietary histidine content on the change in content of skin urocanic acid isomers in hairless mice irradiated with ultraviolet B.
Bioscience, biotechnology, and biochemistry 2001;65(6):1415-8.
2001: Katsumi Shibata; Tsutomu Fukuwatari; Etsuro Sugimoto
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.
Bioscience, biotechnology, and biochemistry 2001;65(6):1339-46.
2001: Tsutomu Fukuwatari; K Shibata; K Ishihara; Tohru Fushiki; Etsuro Sugimoto
Elevation of blood NAD level after moderate exercise in young women and mice.
Journal of nutritional science and vitaminology 2001;47(2):177-9.
2000: K Shibata; Tsutomu Fukuwatari; Etsuro Sugimoto
Reversed-phase high-performance liquid chromatography of nicotinic acid mononucleotide for measurement of quinolinate phosphoribosyltransferase.
Journal of chromatography. B, Biomedical sciences and applications 2000;749(2):281-5.
2000: Katsumi Shibata; M Swabe; Tsutomu Fukuwatari; Etsuro Sugimoto
Efficiency of D-tryptophan as Niacin in rats.
Bioscience, biotechnology, and biochemistry 2000;64(1):206-9.
1999: M Tsuruta; T Kawada; Tsutomu Fukuwatari; Tohru Fushiki
The orosensory recognition of long-chain fatty acids in rats.
Physiology & behavior 1999;66(2):285-8.
1997: Tsutomu Fukuwatari; T Kawada; M Tsuruta; T Hiraoka; T Iwanaga; Etsuro Sugimoto; Tohru Fushiki
Expression of the putative membrane fatty acid transporter (FAT) in taste buds of the circumvallate papillae in rats.
FEBS letters 1997;414(2):461-4.
1995: Y Kamei; Teruo Kawada; Tsutomu Fukuwatari; T Ono; S Kato; E Sugimoto
Cloning and sequencing of the gene encoding the mouse vitamin D receptor.
Gene 1995;152(2):281-2.