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Tohru Funahashi

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Masaya Yamaoka; Yu Tsushima; Yuya Fujishima; Tohru Funahashi; Ayumu Hirata; Kana Inoue; Susumu Kashine; Noriyuki Komura; Norikazu Maeda; Ken-Ichi Matsubara; Keisuke Matsuda; Yuji Matsuzawa; Takuya Mori; Yasuhiko Nakagawa; Seiji Nakamura; Hitoshi Nishizawa; Ryohei Sekimoto; Iichiro Shimomura
Gene expression levels of S100 protein family in blood cells are associated with insulin resistance and inflammation (Peripheral blood S100 mRNAs and metabolic syndrome).
Ayumu Hirata; Ken Kishida; Hironori Kobayashi; Hideaki Nakatsuji; Tohru Funahashi; Iichiro Shimomura
High serum C1q-adiponectin/total adiponectin ratio correlates with coronary artery disease in Japanese type 2 diabetics.
Ayumu Hirata; Ken Kishida; Hironori Kobayashi; Hideaki Nakatsuji; Tohru Funahashi; Iichiro Shimomura
Correlation between serum C1q-adiponectin/total adiponectin ratio and polyvascular lesions detected by vascular ultrasonography in Japanese type 2 diabetics.

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2013: Masaya Yamaoka; Yu Tsushima; Yuya Fujishima; Tohru Funahashi; Ayumu Hirata; Kana Inoue; Susumu Kashine; Noriyuki Komura; Norikazu Maeda; Ken-Ichi Matsubara; Keisuke Matsuda; Yuji Matsuzawa; Takuya Mori; Yasuhiko Nakagawa; Seiji Nakamura; Hitoshi Nishizawa; Ryohei Sekimoto; Iichiro Shimomura
Gene expression levels of S100 protein family in blood cells are associated with insulin resistance and inflammation (Peripheral blood S100 mRNAs and metabolic syndrome).
Biochemical and biophysical research communications 2013;433(4):450-5.
2013: Ayumu Hirata; Ken Kishida; Hironori Kobayashi; Hideaki Nakatsuji; Tohru Funahashi; Iichiro Shimomura
High serum C1q-adiponectin/total adiponectin ratio correlates with coronary artery disease in Japanese type 2 diabetics.
Metabolism: clinical and experimental 2013;62(4):578-85.
2013: Ayumu Hirata; Ken Kishida; Hironori Kobayashi; Hideaki Nakatsuji; Tohru Funahashi; Iichiro Shimomura
Correlation between serum C1q-adiponectin/total adiponectin ratio and polyvascular lesions detected by vascular ultrasonography in Japanese type 2 diabetics.
Metabolism: clinical and experimental 2013;62(3):376-85.
2013: Mitsuyoshi Takahara; Akihito Otsuka; Iichiro Shimomura; Hideaki Fukamizu; Tohru Funahashi; Kikuo Ichihara; Hideaki Kaneto; Naoto Katakami; Ken Kishida; Satoko Kubo; Sai Matsunaga; Tadashi Nakamura
Circulating adiponectin levels and their associated factors in young lean healthy Japanese women.
Journal of atherosclerosis and thrombosis 2013;20(1):57-64.
2013: Hideaki Nakatsuji; Tohru Funahashi; Ken Kishida; Hironori Kobayashi; Tohru Nakagawa; Iichiro Shimomura
Correlation of circulating C1q and C1q-binding adiponectin concentrations with aging in males: a preliminary report.
Diabetology & metabolic syndrome 2013;5(1):17.
2013: Kana Inoue; Ken Kishida; Tohru Funahashi; Ayumu Hirata; Iichiro Shimomura
Low serum eicosapentaenoic acid / arachidonic acid ratio in male subjects with visceral obesity.
Nutrition & metabolism 2013;10(1):25.
2013: Ken Kishida; Naohiro Kishida; Hironori Kobayashi; Hideaki Nakatsuji; Masaaki Arima; Tohru Funahashi; Iichiro Shimomura
Serum C1q- binding adiponectin in maintenance hemodialysis patients.
BMC nephrology 2013;14():50.
2013: Norikazu Maeda; Tohru Funahashi; Iichiro Shimomura
Cardiovascular-metabolic impact of adiponectin and aquaporin.
Endocrine journal 2013;60(3):251-9.
2013: Kohei Okita; Tohru Funahashi; Akihisa Imagawa; Hiromi Iwahashi; Junji Kozawa; Yukiyoshi Okauchi; Iichiro Shimomura
Homeostasis model assessment of insulin resistance for evaluating insulin sensitivity in patients with type 2 diabetes on insulin therapy.
Endocrine journal 2013;60(3):283-90.
2013: Hideaki Nakatsuji; Iichiro Shimomura; Tohru Funahashi; Ken Kishida; Hironori Kobayashi
Three-month treatment with pioglitazone reduces circulating C1q-binding adiponectin complex to total-adiponectin ratio, without changes in body mass index, in people with type 2 diabetes.
Diabetes research and clinical practice 2013;99(1):e14-7.
2013: Hideaki Nakatsuji; Shigeo Takahashi; Hideaki Tanaka; Suguru Akamatsu; Tohru Funahashi; Ken Kishida; Hironori Kobayashi; Tohru Nakagawa; Iichiro Shimomura
Binding of adiponectin and C1q in human serum, and clinical significance of the measurement of C1q-adiponectin / total adiponectin ratio.
Metabolism: clinical and experimental 2013;62(1):109-20.
2012: Aki Hiuge-Shimizu; Yuko Ishizaka; Ken Kishida; Yuji Matsuzawa; Tohru Nakagawa; Tadashi Nakamura; Tetsuya Ohira; Rie Oka; Minoru Okada; Shizu Suzuki; Norihide Takaya; Naoya Watanabe; Minoru Yamakado; Tohru Yoshizumi; Hiroshi Fukuda; Toshiki Fukui; Tohru Funahashi; Iichiro Shimomura
Reduction of visceral fat correlates with the decrease in the number of obesity-related cardiovascular risk factors in Japanese with Abdominal Obesity (VACATION-J Study).
Journal of atherosclerosis and thrombosis 2012;19(11):1006-18.
2012: Ken Kishida; Tohru Funahashi; Iichiro Shimomura
Importance of assessing the effect of statins on the function of high- density lipoproteins on coronary plaque.
Cardiovascular & hematological disorders drug targets 2012;12(1):28-34.
2012: Ayumu Hirata; Aki Hiuge-Shimizu; Ken Kishida; Hideaki Nakatsuji; Tohru Funahashi; Iichiro Shimomura
High serum S100A8/A9 levels and high cardiovascular complication rate in type 2 diabetics with ultrasonographic low carotid plaque density.
Diabetes research and clinical practice 2012;97(1):82-90.
2012: Ken Kishida; Tohru Funahashi; Iichiro Shimomura
Molecular mechanisms of diabetes and atherosclerosis: role of adiponectin.
Endocrine, metabolic & immune disorders drug targets 2012;12(2):118-31.
2012: Ayumu Hirata; Aki Hiuge-Shimizu; Ken Kishida; Hideaki Nakatsuji; Tohru Funahashi; Iichiro Shimomura
Metabolic syndrome correlates with polyvascular lesions detected by systemic vascular ultrasonography in Japanese people with type 2 diabetes.
Diabetes research and clinical practice 2012;96(2):e26-9.
2012: Ken Kishida; Yuji Matsuzawa; Tohru Funahashi; Iichiro Shimomura
Visceral adiposity as a target for the management of the metabolic syndrome.
Annals of medicine 2012;44(3):233-41.
2012: Shunsuke Yamamoto; Masahiko Tsujii; Shusaku Tsutsui; Kenji Watabe; Hiroshi Araki; Tohru Funahashi; Norio Hayashi; Yoshihiro Kamada; Motohiko Kato; Shinji Kihara; Shinichi Kiso; Takashi Kizu; Iichiro Shimomura; Tetsuo Takehara
Protective role of adiponectin against ethanol-induced gastric injury in mice.
American journal of physiology. Gastrointestinal and liver physiology 2012;302(8):G773-80.
2012: Ryohei Sekimoto; Tohru Funahashi; Ken Kishida; Tohru Nakagawa; Hideaki Nakatsuji; Iichiro Shimomura
High circulating levels of S100A8/A9 complex (calprotectin) in male Japanese with abdominal adiposity and dysregulated expression of S100A8 and S100A9 in adipose tissues of obese mice.
Biochemical and biophysical research communications 2012;419(4):782-9.
2012: Ayumu Hirata; Aki Hiuge-Shimizu; Norikazu Maeda; Hideaki Nakatsuji; Takuya Okada; Tohru Funahashi; Iichiro Shimomura
Contribution of glucocorticoid-mineralocorticoid receptor pathway on the obesity-related adipocyte dysfunction.
Biochemical and biophysical research communications 2012;419(2):182-7.
2012: Ken Kishida; Tohru Funahashi; Iichiro Shimomura
Clinical importance of assessment of type 2 diabetes mellitus with visceral obesity. A Japanese perspective.
Current diabetes reviews 2012;8(2):84-91.
2012: Hideaki Nakatsuji; Iichiro Shimomura; Tohru Funahashi; Ken Kishida
Three-month treatment with pioglitazone reduces circulating levels of S100A8/A9 (MRP8/14) complex, a biomarker of inflammation, without changes in body mass index, in type 2 diabetics with abdominal obesity.
Diabetes research and clinical practice 2012;95(3):e58-60.
2012: Naoto Katakami; Koichi Kawai; Ryuzo Kawamori; Norikazu Maeda; Munehide Matsuhisa; Taka-Aki Matsuoka; Keizo Ohno; Takeshi Osonoi; Ikki Shimizu; Tohru Funahashi; Kenichi Imamura; Fukashi Ishibashi; Hideaki Kaneto; Atsunori Kashiwagi; Mitsuyoshi Takahara; Yoshimitsu Yamasaki; Iichiro Shimomura
Adiponectin G276T gene polymorphism is associated with cardiovascular disease in Japanese patients with type 2 diabetes.
Atherosclerosis 2012;220(2):437-42.
2012: Aki Hiuge-Shimizu; Yuko Ishizaka; Ken Kishida; Yuji Matsuzawa; Tohru Nakagawa; Tadashi Nakamura; Rie Oka; Minoru Okada; Shizu Suzuki; Norihide Takaya; Naoya Watanabe; Minoru Yamakado; Tohru Yoshizumi; Hiroshi Fukuda; Toshiki Fukui; Tohru Funahashi; Iichiro Shimomura
Absolute value of visceral fat area measured on computed tomography scans and obesity-related cardiovascular risk factors in large-scale Japanese general population (the VACATION-J study).
Annals of medicine 2012;44(1):82-92.
2012: Masaya Yamaoka; Tohru Funahashi; Aki Hiuge-Shimizu; Akihisa Imagawa; Susumu Kashine; Norikazu Maeda; Ken-ichi Matsubara; Yuji Matsuzawa; Yasuhiko Nakagawa; Seiji Nakamura; Kohei Okita; Iichiro Shimomura
A pilot investigation of visceral fat adiposity and gene expression profile in peripheral blood cells.
PloS one 2012;7(10):e47377.
2012: Yukari Fujita; Tohru Funahashi; Akihisa Imagawa; Hiromi Iwahashi; Hideaki Kaneto; Tetsuhiro Kitamura; Yoko Kobayashi; Junji Kozawa; Norikazu Maeda; Kohei Okita; Michio Otsuki; Shugo Sasaki; Daisuke Tamada; Tetsuyuki Yasuda; Iichiro Shimomura
Successful treatment of reactive hypoglycemia secondary to late dumping syndrome using miglitol.
Internal medicine (Tokyo, Japan) 2012;51(18):2581-5.
2012: Yuya Fujishima; Tohru Funahashi; Ayumu Hirata; Akihisa Imagawa; Kana Inoue; Susumu Kashine; Junji Kozawa; Norikazu Maeda; Hitoshi Nishizawa; Kohei Okita; Tetsuyuki Yasuda; Iichiro Shimomura
Efficacy of liraglutide, a glucagon-like peptide-1 (GLP-1) analogue, on body weight, eating behavior, and glycemic control, in Japanese obese type 2 diabetes.
Cardiovascular diabetology 2012;11():107.
2012: Yasuhiko Nakagawa; Tohru Funahashi; Ken Kishida; Koji Yanagi; Iichiro Shimomura
Coexistence of visceral fat accumulation and sleep-disordered breathing correlates with coronary artery disease.
Journal of atherosclerosis and thrombosis 2012;19(8):728-35.
2012: Tomoko Nakanishi-Minami; Tohru Funahashi; Ken Kishida; Iichiro Shimomura
Sleep-wake cycle irregularities in type 2 diabetics.
Diabetology & metabolic syndrome 2012;4(1):18.
2012: Aki Hiuge-Shimizu; Ryosuke Kametani; Ken Kishida; Hiroshi Kobayashi; Yuji Matsuzawa; Tadashi Nakamura; Akihiro Nomura; Yoichi Nozaki; Tetsuya Ohira; Masaaki Okutsu; Satoru Sumitsuji; Hiroyoshi Yokoi; Tohru Yoshizumi; Tohru Funahashi; Iichiro Shimomura
Coexistence of visceral fat and multiple risk factor accumulations is strongly associated with coronary artery disease in Japanese (the VACATION-J study).
Journal of atherosclerosis and thrombosis 2012;19(7):657-63.
2012: Hideaki Nakatsuji; Tohru Funahashi; Ken Kishida; Tohru Nakagawa; Iichiro Shimomura
Hyperinsulinemia correlates with low levels of plasma B-type natriuretic peptide in Japanese men irrespective of fat distribution.
Cardiovascular diabetology 2012;11():22.
2012: Tomoko Nakanishi-Minami; Yoshiharu Nishida; Munetaka Nishio; Tohru Funahashi; Ken Kishida; Chisa Nakagawa; Yasuhiko Nakagawa; Koji Yanagi; Ryoko Yoshida; Iichiro Shimomura
Metabolic syndrome correlates intracoronary stenosis detected by multislice computed tomography in male subjects with sleep-disordered breathing.
Diabetology & metabolic syndrome 2012;4():6.
2012: Ayumu Hirata; Aki Hiuge-Shimizu; Kana Inoue; Ken Kishida; Hideaki Nakatsuji; Tohru Funahashi; Iichiro Shimomura
High prevalence of gastroesophageal reflux symptoms in type 2 diabetics with hypoadiponectinemia and metabolic syndrome.
Nutrition & metabolism 2012;9(1):4.
2012: Susumu Kashine; Ken Kishida; Tohru Funahashi; Iichiro Shimomura
Characteristics of sleep-disordered breathing in Japanese patients with acromegaly.
Endocrine journal 2012;59(1):31-8.
2011: Ayumu Hirata; Aki Hiuge-Shimizu; Ken Kishida; Hideaki Nakatsuji; Tohru Funahashi; Iichiro Shimomura
Qualitative score of systemic arteriosclerosis by vascular ultrasonography as a predictor of coronary artery disease in type 2 diabetes.
Atherosclerosis 2011;219(2):623-9.
2011: Yasuhiko Nakagawa; Masakiyo Nobuyoshi; Tohru Funahashi; Ken Kishida; Tohru Mazaki; Hiroyoshi Yokoi; Iichiro Shimomura
Impact of sleep-disordered breathing, visceral fat accumulation and adiponectin levels in patients with night-time onset of acute coronary syndrome.
The American journal of cardiology 2011;108(9):1266-71.
2011: Yuko Fujiwara; Tohru Funahashi; Ken Kishida; Munehide Matsuhisa; Iichiro Shimomura; Mitsuyoshi Takahara; Mika Terao; Yasuko Shimizu
Beneficial effects of foot care nursing for people with diabetes mellitus: an uncontrolled before and after intervention study.
Journal of advanced nursing 2011;67(9):1952-62.
2011: Kaori Nakanishi; Yoshito Takeda; Satoshi Tetsumoto; Takeo Iwasaki; Kazuyuki Tsujino; Hanako Kuhara; Yingji Jin; Izumi Nagatomo; Hiroshi Kida; Sho Goya; Takashi Kijima; Norikazu Maeda; Tohru Funahashi; Iichiro Shimomura; Isao Tachibana; Ichiro Kawase
Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: implications for therapy.
American journal of respiratory and critical care medicine 2011;183(9):1164-75.
2011: Aki Hiuge-Shimizu; Norikazu Maeda; Ayumu Hirata; Hideaki Nakatsuji; Kouichi Nakamura; Akira Okuno; Shinji Kihara; Tohru Funahashi; Iichiro Shimomura
Dynamic changes of adiponectin and S100A8 levels by the selective peroxisome proliferator-activated receptor-gamma agonist rivoglitazone.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(4):792-9.
2011: Kana Inoue; Susumu Kashine; Junji Kozawa; Norikazu Maeda; Kohei Okita; Yuya Fujishima; Tohru Funahashi; Aki Hiuge-Shimizu; Akihisa Imagawa; Iichiro Shimomura
Short-term effects of liraglutide on visceral fat adiposity, appetite, and food preference: a pilot study of obese Japanese patients with type 2 diabetes.
Cardiovascular diabetology 2011;10():109.
2011: Kana Inoue; Hiromi Iwahashi; Ken Kishida; Tetsuhiro Kitamura; Junji Kozawa; Norikazu Maeda; Eri Mitsui; Yukiko Nakata; Kohei Okita; Michio Otsuki; Tohru Funahashi; Akihisa Imagawa; Iichiro Shimomura
Right-sided acute suppurative thyroiditis caused by infectious endocarditis.
Internal medicine (Tokyo, Japan) 2011;50(23):2893-7.
2011: Yukiyoshi Okauchi; Kohei Okita; Tohru Funahashi; Akihisa Imagawa; Hiromi Iwahashi; Ken Kishida; Tadashi Nakamura; Midori Noguchi; Tomoko Ogawa; Tetsuya Ohira; Iichiro Shimomura
Cross-sectional and longitudinal study of association between circulating thiobarbituric acid-reacting substance levels and clinicobiochemical parameters in 1,178 middle-aged Japanese men - the Amagasaki Visceral Fat Study.
Nutrition & metabolism 2011;8():82.
2011: Susumu Kashine; Ken Kishida; Yuji Matsuzawa; Kohei Okita; Tohru Funahashi; Tetsuyuki Yasuda; Iichiro Shimomura
Selective contribution of waist circumference reduction on the improvement of sleep-disordered breathing in patients hospitalized with type 2 diabetes mellitus.
Internal medicine (Tokyo, Japan) 2011;50(18):1895-903.
2011: Ken Kishida; Tohru Funahashi; Iichiro Shimomura
Clinical significance of visceral fat reduction through health education in preventing atherosclerotic cardiovascular disease - Lesson from the Amagasaki Visceral Fat Study: A Japanese perspective.
Nutrition & metabolism 2011;8():57.
2011: Miwa Ryo; Tohru Funahashi; Akihisa Imagawa; Hiromi Iwahashi; Ken Kishida; Sumi Kojima; Yuji Matsuzawa; Tadashi Nakamura; Hitoshi Nishizawa; Midori Noguchi; Tomoko Ogawa; Tetsuya Ohira; Yukiyoshi Okauchi; Kohei Okita; Iichiro Shimomura
Health education "Hokenshido" program reduced metabolic syndrome in the Amagasaki visceral fat study. Three-year follow-up study of 3,174 Japanese employees.
Internal medicine (Tokyo, Japan) 2011;50(16):1643-8.
2011: Norikazu Maeda; Tohru Funahashi; Toshiyuki Hibuse; Iichiro Shimomura
[Aquaporin adipose (AQPap)].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 1():325-30.
2011: Ken Kishida; Yuji Matsuzawa; Tohru Funahashi; Hee-Cheol Kang; Kyoung-Kon Kim; Iichiro Shimomura
Relationships between circulating adiponectin levels and fat distribution in obese subjects.
Journal of atherosclerosis and thrombosis 2011;18(7):592-5.
2011: Yasuhiko Nakagawa; Ken Kishida; Shinji Kihara; Ryoko Yoshida; Tohru Funahashi; Iichiro Shimomura
Nocturnal falls of adiponectin levels in sleep apnea with abdominal obesity and impact of hypoxia-induced dysregulated adiponectin production in obese murine mesenteric adipose tissue.
Journal of atherosclerosis and thrombosis 2011;18(3):240-7.
2010: Yukiyoshi Okauchi; Ken Kishida; Tohru Funahashi; Midori Noguchi; Tomoko Ogawa; Miwa Ryo; Kohei Okita; Hiromi Iwahashi; Akihisa Imagawa; Tadashi Nakamura; Yuji Matsuzawa; Iichiro Shimomura
Absolute value of bioelectrical impedance analysis-measured visceral fat area with obesity-related cardiovascular risk factors in Japanese workers.
Journal of atherosclerosis and thrombosis 2010;17(12):1237-45.
2010: Yukiyoshi Okauchi; Ken Kishida; Tohru Funahashi; Midori Noguchi; Sachiko Morita; Tomoko Ogawa; Akihisa Imagawa; Tadashi Nakamura; Yuji Matsuzawa; Iichiro Shimomura
4-year follow-up of cardiovascular events and changes in visceral fat accumulation after health promotion program in the Amagasaki Visceral Fat Study.
Atherosclerosis 2010;212(2):698-700.
2010: Hideharu Ogiyama; Yoshihiro Kamada; Shinichi Kiso; Hiroshi Araki; Takuya Yamada; Tamao Nishihara; Kenji Watabe; Yoshihiro Tochino; Shinji Kihara; Tohru Funahashi; Keishi Kanno; Iichiro Shimomura; Shusaku Tsutsui; Susumu Tazuma; Norio Hayashi
Lack of adiponectin promotes formation of cholesterol gallstones in mice.
Biochemical and biophysical research communications 2010;399(3):352-8.
2010: Sachiko Tamba; Hideaki Nakatsuji; Ken Kishida; Midori Noguchi; Tomoko Ogawa; Yukiyoshi Okauchi; Hitoshi Nishizawa; Akihisa Imagawa; Tadashi Nakamura; Yuji Matsuzawa; Tohru Funahashi; Iichiro Shimomura
Relationship between visceral fat accumulation and urinary albumin-creatinine ratio in middle-aged Japanese men.
Atherosclerosis 2010;211(2):601-5.
2010: Takuya Yamada; Hiroshi Araki; Kenji Watabe; Yoshihiro Kamada; Shinichi Kiso; Hideharu Ogiyama; Tamao Nishihara; Shinji Kihara; Tohru Funahashi; Iichiro Shimomura; Shusaku Tsutsui; Norio Hayashi
Adiponectin deficiency enhanced the severity of cerulein-induced chronic pancreatitis in mice.
Journal of gastroenterology 2010;45(7):742-9.
2010: Noriyuki Komura; Shinji Kihara; Mina Sonoda; Norikazu Maeda; Yoshihiro Tochino; Tohru Funahashi; Iichiro Shimomura
Increment and impairment of adiponectin in renal failure.
Cardiovascular research 2010;86(3):471-7.
2010: Susumu Kashine; Ken Kishida; Tohru Funahashi; Yasuhiko Nakagawa; Michio Otuki; Kohei Okita; Hiromi Iwahashi; Shinji Kihara; Tadashi Nakamura; Yuji Matsuzawa; Iichiro Shimomura
Characteristics of sleep-disordered breathing in Japanese patients with type 2 diabetes mellitus.
Metabolism: clinical and experimental 2010;59(5):690-6.
2010: Hideaki Nakatsuji; Ken Kishida; Teruo Kitamura; Chika Nakajima; Tohru Funahashi; Iichiro Shimomura
Dysregulation of glucose, insulin, triglyceride, blood pressure, and oxidative stress after an oral glucose tolerance test in men with abdominal obesity.
Metabolism: clinical and experimental 2010;59(4):520-6.
2010: Y Kuroda; H Kuriyama; Shinji Kihara; Ken Kishida; Norikazu Maeda; Toshiyuki Hibuse; Hitoshi Nishizawa; M Matsuda; Tohru Funahashi; Iichiro Shimomura
Insulin-mediated regulation of decidual protein induced by progesterone (DEPP) in adipose tissue and liver.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2010;42(3):173-7.
2010: Hideaki Nakatsuji; Norikazu Maeda; Toshiyuki Hibuse; Aki Hiuge; Ayumu Hirata; Yohei Kuroda; Ken Kishida; Shinji Kihara; Tohru Funahashi; Iichiro Shimomura
Reciprocal regulation of natriuretic peptide receptors by insulin in adipose cells.
Biochemical and biophysical research communications 2010;392(1):100-5.
2010: Koichi Fujita; Norikazu Maeda; Junji Kozawa; Kakeyoshi Murano; Kohei Okita; Hiromi Iwahashi; Shinji Kihara; Masato Ishigami; Motoko Omura; Tadashi Nakamura; Kohji Shirai; Taku Yamamura; Tohru Funahashi; Iichiro Shimomura
A case of adolescent hyperlipoproteinemia with xanthoma and acute pancreatitis, associated with decreased activities of lipoprotein lipase and hepatic triglyceride lipase.
Internal medicine (Tokyo, Japan) 2010;49(22):2467-72.
2009: Hannah Kanety; Rina Hemi; Shira Ginsberg; Clara Pariente; Eleanor Yissachar; Ehud Barhod; Tohru Funahashi; Zvi Laron
Total and high molecular weight adiponectin are elevated in patients with Laron syndrome despite marked obesity.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161(6):837-44.
2009: Yoshihiro Kamada; Tadashi Nakamura; Tohru Funahashi; Miwa Ryo; Hitoshi Nishizawa; Yukiyoshi Okauchi; Juichi Fukushima; Yuichi Yoshida; Shinichi Kiso; Iichiro Shimomura; Norio Hayashi
Visceral obesity and hypoadiponectinemia are significant determinants of hepatic dysfunction: An epidemiologic study of 3827 Japanese subjects.
Journal of clinical gastroenterology 2009;43(10):995-1000.
2009: Akira Tsujimura; Shingo Takada; Yasuhiro Matsuoka; Jiro Nakayama; Tetsuya Takao; Yasushi Miyagawa; Mina Sonoda; Hitoshi Nishizawa; Hiromi Iwahashi; Tohru Funahashi; Norio Nonomura; Akihiko Okuyama
Adiponectin and testosterone in patients with symptoms of late-onset hypogonadism: is there a link?
International journal of urology : official journal of the Japanese Urological Association 2009;16(10):830-5.
2009: Ayumu Hirata; Norikazu Maeda; Aki Hiuge; Toshiyuki Hibuse; Koichi Fujita; Takuya Okada; Shinji Kihara; Tohru Funahashi; Iichiro Shimomura
Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice.
Cardiovascular research 2009;84(1):164-72.
2009: Juichi Fukushima; Yoshihiro Kamada; Hitoshi Matsumoto; Yuichi Yoshida; Hisao Ezaki; Takayo Takemura; Yukiko Saji; Takumi Igura; Shusaku Tsutsui; Shinji Kihara; Tohru Funahashi; Iichiro Shimomura; Shinji Tamura; Shinichi Kiso; Norio Hayashi
Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(7):724-38.
2009: Toshiyuki Hibuse; Norikazu Maeda; Hideaki Nakatsuji; Yoshihiro Tochino; Koichi Fujita; Shinji Kihara; Tohru Funahashi; Iichiro Shimomura
The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator.
Cardiovascular research 2009;83(1):34-41.
2009: Osamu Tsukamoto; Masashi Fujita; Mahoto Kato; Satoru Yamazaki; Yoshihiro Asano; Akiko Ogai; Hidetoshi Okazaki; Mitsutoshi Asai; Yoko Nagamachi; Norikazu Maeda; Yasunori Shintani; Tetsuo Minamino; Masanori Asakura; Ichiro Kishimoto; Tohru Funahashi; Hitonobu Tomoike; Masafumi Kitakaze
Natriuretic peptides enhance the production of adiponectin in human adipocytes and in patients with chronic heart failure.
Journal of the American College of Cardiology 2009;53(22):2070-7.
2009: Yasuhiko Nakagawa; Ken Kishida; Shinji Kihara; Tohru Funahashi; Iichiro Shimomura
Adiponectin ameliorates hypoxia-induced pulmonary arterial remodeling.
Biochemical and biophysical research communications 2009;382(1):183-8.
2009: Makoto Nishida; Tohru Funahashi
[Validity of indices (BMI, Rohrer index, Broca method) for assessment of obesity].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(2):301-6.
2009: Hisao Ezaki; Yuichi Yoshida; Yukiko Saji; Takayo Takemura; Juichi Fukushima; Hitoshi Matsumoto; Yoshihiro Kamada; Akira Wada; Takumi Igura; Shinji Kihara; Tohru Funahashi; Iichiro Shimomura; Shinji Tamura; Shinichi Kiso; Norio Hayashi
Delayed liver regeneration after partial hepatectomy in adiponectin knockout mice.
Biochemical and biophysical research communications 2009;378(1):68-72.
2009: Yukiyoshi Okauchi; Takao Nammo; Hiromi Iwahashi; Takashi Kizu; Isao Hayashi; Kohei Okita; Kazuya Yamagata; Sae Uno; Fumie Katsube; Munehide Matsuhisa; Ken Kato; Katsuyuki Aozasa; Tonsok Kim; Keigo Osuga; Shoji Nakamori; Yasuhiro Tamaki; Tohru Funahashi; Jun-ichiro Miyagawa; Iichiro Shimomura
Glucagonoma diagnosed by arterial stimulation and venous sampling (ASVS).
Internal medicine (Tokyo, Japan) 2009;48(12):1025-30.
2008: Yukiyoshi Okauchi; Hiromi Iwahashi; Kohei Okita; Ming Yuan; Morihiro Matsuda; Toshiya Tanaka; Jun-ichiro Miyagawa; Tohru Funahashi; Yukio Horikawa; Iichiro Shimomura; Kazuya Yamagata
PGC-1alpha Gly482Ser polymorphism is associated with the plasma adiponectin level in type 2 diabetic men.
Endocrine journal 2008;55(6):991-7.
2008: Tamao Nishihara; Miyako Baba; Morihiro Matsuda; Masahiro Inoue; Yasuko Nishizawa; Atsunori Fukuhara; Hiroshi Araki; Shinji Kihara; Tohru Funahashi; Shinji Tamura; Norio Hayashi; Hiroyasu Iishi; Iichiro Shimomura
Adiponectin deficiency enhances colorectal carcinogenesis and liver tumor formation induced by azoxymethane in mice.
World journal of gastroenterology : WJG 2008;14(42):6473-80.
2008: Norikazu Maeda; Tohru Funahashi; Iichiro Shimomura
Metabolic impact of adipose and hepatic glycerol channels aquaporin 7 and aquaporin 9.
Nature clinical practice. Endocrinology & metabolism 2008;4(11):627-34.
2008: Hiroyuki Araki; T Nishihara; Morihiro Matsuda; Atsunori Fukuhara; Shinji Kihara; Tohru Funahashi; T R Kataoka; Yoshihiro Kamada; Tatsuya Kiyohara; Shinji Tamura; Norio Hayashi; Iichiro Shimomura
Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet.
Gut 2008;57(10):1431-40.
2008: Takahiro Ohara; Jiyoong Kim; Masanori Asakura; Hiroshi Asanuma; Satoshi Nakatani; Kazuhiko Hashimura; Hideaki Kanzaki; Tohru Funahashi; Hitonobu Tomoike; Masafumi Kitakaze
Plasma adiponectin is associated with plasma brain natriuretic peptide and cardiac function in healthy subjects.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(5):825-31.
2008: Koichi Fujita; Norikazu Maeda; Mina Sonoda; Koji Ohashi; Toshiyuki Hibuse; Hitoshi Nishizawa; Makoto Nishida; Aki Hiuge; Akifumi Kurata; Shinji Kihara; Iichiro Shimomura; Tohru Funahashi
Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):863-70.
2008: Yasuhiko Nakagawa; Ken Kishida; Shinji Kihara; Mina Sonoda; Ayumu Hirata; Atsutaka Yasui; Hitoshi Nishizawa; Tadashi Nakamura; Ryoko Yoshida; Iichiro Shimomura; Tohru Funahashi
Nocturnal reduction in circulating adiponectin concentrations related to hypoxic stress in severe obstructive sleep apnea-hypopnea syndrome.
American journal of physiology. Endocrinology and metabolism 2008;294(4):E778-84.
2008: Takuya Okada; Hitoshi Nishizawa; Akifumi Kurata; Sachiko Tamba; Mina Sonoda; Atsutaka Yasui; Yohei Kuroda; Toshiyuki Hibuse; Norikazu Maeda; Shinji Kihara; Tohru Hadama; Kazuki Tobita; Suguru Akamatsu; Kazuhisa Maeda; Iichiro Shimomura; Tohru Funahashi
URB is abundantly expressed in adipose tissue and dysregulated in obesity.
Biochemical and biophysical research communications 2008;367(2):370-6.
2008: Ayumi Tokunaga; Atsuko Miura; Yukiyoshi Okauchi; Katsumori Segawa; Atsunori Fukuhara; Kohei Okita; Masahiko Takahashi; Tohru Funahashi; Jun-ichiro Miyagawa; Iichiro Shimomura; Kazuya Yamagata
The -1535 promoter variant of the visfatin gene is associated with serum triglyceride and HDL-cholesterol levels in Japanese subjects.
Endocrine journal 2008;55(1):205-12.
2008: Etsuko Fukuda-Akita; Kohei Okita; Yukiyoshi Okauchi; Miwa Ryo; Tadashi Nakamura; Tohru Funahashi; Hiromi Iwahashi; Iichiro Shimomura; Junichiro Miyagawa; Kazuya Yamagata
Impaired early insulin secretion in Japanese type 2 diabetes with metabolic syndrome.
Diabetes research and clinical practice 2008;79(3):482-9.
2008: Sachiko Tamba; Hitoshi Nishizawa; Tohru Funahashi; Yukiyoshi Okauchi; Tomoko Ogawa; Midori Noguchi; Koichi Fujita; Miwa Ryo; Shinji Kihara; Hiromi Iwahashi; Kazuya Yamagata; Tadashi Nakamura; Iichiro Shimomura; Yuji Matsuzawa
Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men.
Internal medicine (Tokyo, Japan) 2008;47(13):1175-80.
2008: Noriyuki Komura; Shinji Kihara; Mina Sonoda; Masahiro Kumada; Koichi Fujita; Aki Hiuge; Takuya Okada; Yasuhiko Nakagawa; Sachiko Tamba; Yohei Kuroda; Noriyuki Hayashi; Satoru Sumitsuji; Toshiharu Kawamoto; Satoru Matsumoto; Noriyuki Ouchi; Yukio Arita; Yoshihisa Okamoto; Iichiro Shimomura; Tohru Funahashi; Yuji Matsuzawa
Clinical significance of high-molecular weight form of adiponectin in male patients with coronary artery disease.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(1):23-8.
2008: Tomomi Fujisawa; Hiroshi Ikegami; Soji Kasayama; Munehide Matsuhisa; Yoshimitsu Yamasaki; Jun-ichiro Miyagawa; Tohru Funahashi; Iichiro Shimomura
Age-dependent difference in factors affecting choice of system for self-monitoring of blood glucose.
Diabetes research and clinical practice 2008;79(1):103-7.
2008: Toshiyuki Takagi; Morihiro Matsuda; Manabu Abe; Hironori Kobayashi; Atsunori Fukuhara; Ryutaro Komuro; Shinji Kihara; Muriel J Caslake; Alex McMahon; James Shepherd; Tohru Funahashi; Iichiro Shimomura
Effect of pravastatin on the development of diabetes and adiponectin production.
Atherosclerosis 2008;196(1):114-21.
2007: Atsutaka Yasui; Hitoshi Nishizawa; Yosuke Okuno; Kentaro Morita; Hironori Kobayashi; Kenichiro Kawai; Morihiro Matsuda; Ken Kishida; Shinji Kihara; Yasutomi Kamei; Yoshihiro Ogawa; Tohru Funahashi; Iichiro Shimomura
Foxo1 represses expression of musclin, a skeletal muscle-derived secretory factor.
Biochemical and biophysical research communications 2007;364(2):358-65.
2007: Atsunori Fukuhara; Morihiro Matsuda; Masako Nishizawa; Katsumori Segawa; Masaki Tanaka; Kae Kishimoto; Yasushi Matsuki; Mirei Murakami; Tomoko Ichisaka; Hiroko Murakami; Eijiro Watanabe; Toshiyuki Takagi; Megumi Akiyoshi; Tsuguteru Ohtsubo; Shinji Kihara; Shizuya Yamashita; Makoto Makishima; Tohru Funahashi; Shinya Yamanaka; Ryuji Hiramatsu; Yuji Matsuzawa; Iichiro Shimomura
Retraction.
Science (New York, N.Y.) 2007;318(5850):565.
2007: Yoshihiro Kamada; Hitoshi Matsumoto; Shinji Tamura; Juichi Fukushima; Shinichi Kiso; Koji Fukui; Takumi Igura; Norikazu Maeda; Shinji Kihara; Tohru Funahashi; Yuji Matsuzawa; Iichiro Shimomura; Norio Hayashi
Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model.
Journal of hepatology 2007;47(4):556-64.
2007: Koji Ohashi; Hirotsugu Iwatani; Shinji Kihara; Yasuhiko Nakagawa; Noriyuki Komura; Koichi Fujita; Norikazu Maeda; Makoto Nishida; Fumie Katsube; Iichiro Shimomura; Takahito Ito; Tohru Funahashi
Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(9):1910-7.
2007: Yukiyoshi Okauchi; Hitoshi Nishizawa; Tohru Funahashi; Tomoko Ogawa; Midori Noguchi; Miwa Ryo; Shinji Kihara; Hiromi Iwahashi; Kazuya Yamagata; Tadashi Nakamura; Iichiro Shimomura; Yuji Matsuzawa
Reduction of visceral fat is associated with decrease in the number of metabolic risk factors in Japanese men.
Diabetes care 2007;30(9):2392-4.
2007: Noriyuki Hayashi; Tohru Funahashi
[Hyperlipidemia in endocrine disease].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 7():417-20.
2007: Tohru Funahashi
[Definition of metabolic syndrome in Japan--concept and perspective].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 7():84-90.
2007: Munehide Matsuhisa; Yoshimitsu Yamasaki; Masanori Emoto; Michio Shimabukuro; Shinichiro Ueda; Tohru Funahashi; Yuji Matsuzawa
A novel index of insulin resistance determined from the homeostasis model assessment index and adiponectin levels in Japanese subjects.
Diabetes research and clinical practice 2007;77(1):151-4.
2007: Makoto Nishida; Tohru Funahashi; Iichiro Shimomura
Pathophysiological significance of adiponectin.
Medical molecular morphology 2007;40(2):55-67.
2007: Koichi Fujita; Tohru Funahashi
[Adipocytokine].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 4():191-5.
2007: Aki Hiuge; Alexander Tenenbaum; Norikazu Maeda; Michal Benderly; Masahiro Kumada; Enrique Z Fisman; David Tanne; Zipora Matas; Toshiyuki Hibuse; Koichi Fujita; Hitoshi Nishizawa; Yehuda Adler; Michael Motro; Shinji Kihara; Iichiro Shimomura; Solomon Behar; Tohru Funahashi
Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):635-41.
2007: Tohru Funahashi; Yuji Matsuzawa
Metabolic syndrome: clinical concept and molecular basis.
Annals of medicine 2007;39(7):482-94.
2007: Tadashi Nakamura; Yukiyoshi Okauchi; Miwa Ryo; Tohru Funahashi; Iichiro Shimomura
Clinical diagnosis of metabolic syndrome 3. Diagnostic criteria for metabolic syndrome in Japan and its clinical significance.
Internal medicine (Tokyo, Japan) 2007;46(16):1287.
2006: Miwa Ryo; Tohru Funahashi
[Global diagnosis definition of the metabolic syndrome and its management].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():463-9.
2006: Miwa Ryo; Tohru Funahashi
[Definition and characteristics of the metabolic syndrome in Japan].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():457-62.
2006: Norikazu Maeda; Tohru Funahashi
[Gene mutations of adipocytokine associated with metabolic syndrome].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():330-3.
2006: Norikazu Maeda; Toshiyuki Hibuse; Tohru Funahashi
[Aquaporin adipose (AQPap)].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():277-81.
2006: Morihiro Matsuda; Tohru Funahashi
[Adiponectin, visfatin, PAI-1].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():212-6.
2006: Norikazu Maeda; Tohru Funahashi
[Fat distribution and its regulation].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():188-91.
2006: Yoshio Iwashima; Takeshi Horio; Masahiro Kumada; Yoshihiko Suzuki; Shinji Kihara; Hiromi Rakugi; Yuhei Kawano; Tohru Funahashi; Toshio Ogihara
Adiponectin and renal function, and implication as a risk of cardiovascular disease.
The American journal of cardiology 2006;98(12):1603-8.
2006: Koichi Fujita; Hitoshi Nishizawa; Tohru Funahashi; Iichiro Shimomura; Michio Shimabukuro
Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome.
Circulation journal : official journal of the Japanese Circulation Society 2006;70(11):1437-42.
2006: A Kurata; Hitoshi Nishizawa; Shinji Kihara; Norikazu Maeda; M Sonoda; T Okada; Koji Ohashi; Toshiyuki Hibuse; Koichi Fujita; A Yasui; Aki Hiuge; Masahiro Kumada; Hiroshi Kuriyama; Iichiro Shimomura; Tohru Funahashi
Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation.
Kidney international 2006;70(10):1717-24.
2006: Noriyuki Komura; Tohru Funahashi
[Obesity].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 7():705-8.
2006: Katsumori Segawa; Atsunori Fukuhara; Naomi Hosogai; Kentaro Morita; Yosuke Okuno; Masaki Tanaka; Yasuhiko Nakagawa; Shinji Kihara; Tohru Funahashi; Ryutaro Komuro; Morihiro Matsuda; Iichiro Shimomura
Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism.
Biochemical and biophysical research communications 2006;349(3):875-82.
2006: Yoshio Iwashima; Takeshi Horio; Yoshihiko Suzuki; Shinji Kihara; Hiromi Rakugi; Kenji Kangawa; Tohru Funahashi; Toshio Ogihara; Yuhei Kawano
Adiponectin and inflammatory markers in peripheral arterial occlusive disease.
Atherosclerosis 2006;188(2):384-90.
2006: Koji Ohashi; Tohru Funahashi
[Mutations and polymorphisms in adiponectin gene].
Nihon rinsho. Japanese journal of clinical medicine 2006;Suppl 3():264-8.
2006: Tamao Nishihara; Morihiro Matsuda; Hiroshi Araki; Kazuya Oshima; Shinji Kihara; Tohru Funahashi; Iichiro Shimomura
Effect of adiponectin on murine colitis induced by dextran sulfate sodium.
Gastroenterology 2006;131(3):853-61.
2006: Tohru Funahashi; Yuji Matsuzawa
Hypoadiponectinemia: a common basis for diseases associated with overnutrition.
Current atherosclerosis reports 2006;8(5):433-8.
2006: Toshiyuki Hibuse; Norikazu Maeda; Azumi Nagasawa; Tohru Funahashi
Aquaporins and glycerol metabolism.
Biochimica et biophysica acta 2006;1758(8):1004-11.
2006: Koji Ohashi; Tohru Funahashi
[Adiponectin].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 5():163-7.
2006: Hitoshi Matsumoto; Shinji Tamura; Yoshihiro Kamada; Shinichi Kiso; Juichi Fukushima; Akira Wada; Norikazu Maeda; Shinji Kihara; Tohru Funahashi; Yuji Matsuzawa; Iichiro Shimomura; Norio Hayashi
Adiponectin deficiency exacerbates lipopolysaccharide/D-galactosamine-induced liver injury in mice.
World journal of gastroenterology : WJG 2006;12(21):3352-8.
2006: Koji Ohashi; Shinji Kihara; Noriyuki Ouchi; Masahiro Kumada; Koichi Fujita; Aki Hiuge; Toshiyuki Hibuse; Miwa Ryo; Hitoshi Nishizawa; Norikazu Maeda; Kazuhisa Maeda; Rei Shibata; Kenneth Walsh; Tohru Funahashi; Iichiro Shimomura
Adiponectin replenishment ameliorates obesity-related hypertension.
Hypertension 2006;47(6):1108-16.
2006: Hidetoshi Ujiie; Kenji Oritani; Hisashi Kato; Takafumi Yokota; Ichiro Takahashi; Tetsuo Maeda; Hiroaki Masaie; Michiko Ichii; Yoshihiro Kamada; Shinji Tamura; Shinji Kihara; Tohru Funahashi; Yoshiaki Tomiyama; Yuzuru Kanakura
Identification of amino-terminal region of adiponectin as a physiologically functional domain.
Journal of cellular biochemistry 2006;98(1):194-207.
2006: Yasuo Miyoshi; Tohru Funahashi; Sachiyo Tanaka; Tetsuya Taguchi; Yasuhiro Tamaki; Iichiro Shimomura; Shinzaburo Noguchi
High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels.
International journal of cancer. Journal international du cancer 2006;118(6):1414-9.
2006: Yoshihisa Okamoto; Shinji Kihara; Tohru Funahashi; Yuji Matsuzawa; Peter Libby
Adiponectin: a key adipocytokine in metabolic syndrome.
Clinical science (London, England : 1979) 2006;110(3):267-78.
2006: Tohru Funahashi; Azumi Nagasawa; Toshiyuki Hibuse; Norikazu Maeda
Impact of glycerol gateway molecule in adipocytes.
Cellular and molecular biology (Noisy-le-Grand, France) 2006;52(7):40-5.
2006: Toshiyuki Hibuse; Tohru Funahashi
[Adipocytokines and diabetes in the elderly].
Nihon rinsho. Japanese journal of clinical medicine 2006;64(1):2-5.
2006: Hisashi Kato; Hirokazu Kashiwagi; Masamichi Shiraga; Seiji Tadokoro; Tsuyoshi Kamae; Hidetoshi Ujiie; Shigenori Honda; Shigeki Miyata; Yoshinobu Ijiri; Junichiro Yamamoto; Norikazu Maeda; Tohru Funahashi; Yoshiyuki Kurata; Iichiro Shimomura; Yoshiaki Tomiyama; Yuzuru Kanakura
Adiponectin acts as an endogenous antithrombotic factor.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):224-30.
2005: Yulin Liao; Seiji Takashima; Norikazu Maeda; Noriyuki Ouchi; Kazuo Komamura; Iichiro Shimomura; Masatsugu Hori; Yuji Matsuzawa; Tohru Funahashi; Masafumi Kitakaze
Exacerbation of heart failure in adiponectin-deficient mice due to impaired regulation of AMPK and glucose metabolism.
Cardiovascular research 2005;67(4):705-13.
2005: Toshiyuki Hibuse; Norikazu Maeda; Tohru Funahashi; Kaori Yamamoto; Azumi Nagasawa; Wataru Mizunoya; Ken Kishida; Kazuo Inoue; Hiroshi Kuriyama; Tadashi Nakamura; Tohru Fushiki; Shinji Kihara; Iichiro Shimomura
Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):10993-8.
2005: Miwa Ryo; Tohru Funahashi
[Adiponectin].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 8():595-9.
2005: Takeshi Horio; Masaaki Suzuki; Kazutaka Suzuki; Itaru Takamisawa; Aki Hiuge; Kei Kamide; Shin Takiuchi; Yoshio Iwashima; Shinji Kihara; Tohru Funahashi; Yasunao Yoshimasa; Yuhei Kawano
Pioglitazone improves left ventricular diastolic function in patients with essential hypertension.
American journal of hypertension 2005;18(7):949-57.
2005: Yoshio Iwashima; Tomohiro Katsuya; Kazuhiko Ishikawa; Iwao Kida; Mitsuru Ohishi; Takeshi Horio; Noriyuki Ouchi; Koji Ohashi; Shinji Kihara; Tohru Funahashi; Hiromi Rakugi; Toshio Ogihara
Association of hypoadiponectinemia with smoking habit in men.
Hypertension 2005;45(6):1094-100.
2005: Kouichi Yamamoto; Tatsuya Kiyohara; Yoko Murayama; Shinji Kihara; Yoshihisa Okamoto; Tohru Funahashi; Takahito Ito; Riichiro Nezu; S Tsutsui; Jun-ichiro Miyagawa; Shinji Tamura; Yuji Matsuzawa; Iichiro Shimomura; Yasuhisa Shinomura
Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease.
Gut 2005;54(6):789-96.
2005: Miwa Ryo; Kazuhisa Maeda; Tomohiro Onda; Mitsuhiro Katashima; Akiko Okumiya; Makoto Nishida; Tohru Yamaguchi; Tohru Funahashi; Yuji Matsuzawa; Tadashi Nakamura; Iichiro Shimomura
A new simple method for the measurement of visceral fat accumulation by bioelectrical impedance.
Diabetes care 2005;28(2):451-3.
2005: Atsunori Fukuhara; Morihiro Matsuda; Masako Nishizawa; Katsumori Segawa; Masaki Tanaka; Kae Kishimoto; Yasushi Matsuki; Mirei Murakami; Tomoko Ichisaka; Hiroko Murakami; Eijiro Watanabe; Toshiyuki Takagi; Megumi Akiyoshi; Tsuguteru Ohtsubo; Shinji Kihara; Shizuya Yamashita; Makoto Makishima; Tohru Funahashi; Shinya Yamanaka; Ryuji Hiramatsu; Yuji Matsuzawa; Iichiro Shimomura
Visfatin: a protein secreted by visceral fat that mimics the effects of insulin.
Science (New York, N.Y.) 2005;307(5708):426-30.
2004: Norikazu Maeda; Tohru Funahashi; Toshiyuki Hibuse; Azumi Nagasawa; Ken Kishida; Hiroshi Kuriyama; Tadashi Nakamura; Shinji Kihara; Iichiro Shimomura; Yuji Matsuzawa
Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(51):17801-6.
2004: Miwa Ryo; Tadashi Nakamura; Shinji Kihara; Masahiro Kumada; Satomi Shibazaki; Mihoko Takahashi; Masaki Nagai; Yuji Matsuzawa; Tohru Funahashi
Adiponectin as a biomarker of the metabolic syndrome.
Circulation journal : official journal of the Japanese Circulation Society 2004;68(11):975-81.
2004: Norikazu Maeda; Tohru Funahashi
[Adiponectin knockout mice].
Nihon rinsho. Japanese journal of clinical medicine 2004;62(6):1067-76.
2004: Yoshio Iwashima; Tomohiro Katsuya; Kazuhiko Ishikawa; Noriyuki Ouchi; Mitsuru Ohishi; Ken Sugimoto; Yuxiao Fu; Masaharu Motone; Kouichi Yamamoto; Akiko Matsuo; Koji Ohashi; Shinji Kihara; Tohru Funahashi; Hiromi Rakugi; Yuji Matsuzawa; Toshio Ogihara
Hypoadiponectinemia is an independent risk factor for hypertension.
Hypertension 2004;43(6):1318-23.
2004: Masahiro Kumada; Shinji Kihara; Noriyuki Ouchi; Hideki Kobayashi; Yoshihisa Okamoto; Koji Ohashi; Kazuhisa Maeda; Hiroyuki Nagaretani; Ken Kishida; Norikazu Maeda; Azumi Nagasawa; Tohru Funahashi; Yuji Matsuzawa
Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages.
Circulation 2004;109(17):2046-9.
2004: Koji Ohashi; Noriyuki Ouchi; Shinji Kihara; Tohru Funahashi; Tadashi Nakamura; Satoru Sumitsuji; Toshiharu Kawamoto; Satoru Matsumoto; Hiroyuki Nagaretani; Masahiro Kumada; Yoshihisa Okamoto; Hitoshi Nishizawa; Ken Kishida; Norikazu Maeda; Hisatoyo Hiraoka; Yoshio Iwashima; Kazuhiko Ishikawa; Mitsuru Ohishi; Tomohiro Katsuya; Hiromi Rakugi; Toshio Ogihara; Yuji Matsuzawa
Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease.
Journal of the American College of Cardiology 2004;43(7):1195-200.
2004: Hideki Kobayashi; Noriyuki Ouchi; Shinji Kihara; Kenneth Walsh; Masahiro Kumada; Yuki Abe; Tohru Funahashi; Yuji Matsuzawa
Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin.
Circulation research 2004;94(4):e27-31.
2004: Masahiro Kumada; Shinji Kihara; Tohru Funahashi; Yuji Matsuzawa
[High sensitivity C-reactive protein analysis in th diagnosis of arteriosclerosis].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 3():292-5.
2004: Yuji Matsuzawa; Tohru Funahashi; Shinji Kihara; Iichiro Shimomura
Adiponectin and metabolic syndrome.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):29-33.
2003: Yoshihiro Kamada; Shinji Tamura; Shinichi Kiso; Hitoshi Matsumoto; Yukiko Saji; Yuichi Yoshida; Koji Fukui; Norikazu Maeda; Hitoshi Nishizawa; Hiroyuki Nagaretani; Yoshihisa Okamoto; Shinji Kihara; Jun-ichiro Miyagawa; Yasuhisa Shinomura; Tohru Funahashi; Yuji Matsuzawa
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin.
Gastroenterology 2003;125(6):1796-807.
2003: Noriyuki Ouchi; Shinji Kihara; Tohru Funahashi; Yuji Matsuzawa; Kenneth Walsh
Obesity, adiponectin and vascular inflammatory disease.
Current opinion in lipidology 2003;14(6):561-6.
2003: Azumi Nagasawa; Kensuke Fukui; Makiko Kojima; Ken Kishida; Norikazu Maeda; Hiroyuki Nagaretani; Toshiyuki Hibuse; Hitoshi Nishizawa; Shinji Kihara; Masako Waki; Kiyoharu Takamatsu; Tohru Funahashi; Yuji Matsuzawa
Divergent effects of soy protein diet on the expression of adipocytokines.
Biochemical and biophysical research communications 2003;311(4):909-14.
2003: Yasuo Miyoshi; Tohru Funahashi; Shinji Kihara; Tetsuya Taguchi; Yasuhiro Tamaki; Yuji Matsuzawa; Shinzaburo Noguchi
Association of serum adiponectin levels with breast cancer risk.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5699-704.
2003: Ken Kishida; Makoto Moriwaki; Jun-ichiro Miyagawa; Kohei Okita; Takashi Kondo; Kimiko Itoh; Satoshi Umemura; Junji Kozawa; Hiromi Iwahashi; Tohru Yoshizumi; Akihisa Imagawa; Kazuya Yamagata; Takao Maruyama; Hiroyuki Toyoshima; Eiji Kurokawa; Tohru Funahashi; Yuji Matsuzawa
Successful use of 111In-pentetrotide scintigraphy for localizing ectopic adrenocorticotropin-producing bronchial carcinoid tumor in a patient with Cushing's syndrome.
Internal medicine (Tokyo, Japan) 2003;42(10):996-1005.
2003: Hiromi Iwahashi; Tohru Funahashi; Nobuo Kurokawa; Kouichi Sayama; E Fukuda; K Okita; Akihisa Imagawa; Kazuya Yamagata; Iichiro Shimomura; Jun-ichiro Miyagawa; Yuji Matsuzawa
Plasma adiponectin levels in women with anorexia nervosa.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2003;35(9):537-40.
2003: Noriyuki Ouchi; Mitsuru Ohishi; Shinji Kihara; Tohru Funahashi; Tadashi Nakamura; Hiroyuki Nagaretani; Masahiro Kumada; Koji Ohashi; Yoshihisa Okamoto; Hitoshi Nishizawa; Ken Kishida; Norikazu Maeda; Azumi Nagasawa; Hideki Kobayashi; Hisatoyo Hiraoka; Norio Komai; Masaharu Kaibe; Hiromi Rakugi; Toshio Ogihara; Yuji Matsuzawa
Association of hypoadiponectinemia with impaired vasoreactivity.
Hypertension 2003;42(3):231-4.
2003: Masanori Iwaki; Morihiro Matsuda; Norikazu Maeda; Tohru Funahashi; Yuji Matsuzawa; Makoto Makishima; Iichiro Shimomura
Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors.
Diabetes 2003;52(7):1655-63.
2003: Ken Kishida; Hiroyuki Nagaretani; Hidehiko Kondo; Hideki Kobayashi; Sachiyo Tanaka; Norikazu Maeda; Azumi Nagasawa; Toshiyuki Hibuse; Koji Ohashi; Masahiro Kumada; Hitoshi Nishizawa; Yoshihisa Okamoto; Noriyuki Ouchi; Kazuhisa Maeda; Shinji Kihara; Tohru Funahashi; Yuji Matsuzawa
Disturbed secretion of mutant adiponectin associated with the metabolic syndrome.
Biochemical and biophysical research communications 2003;306(1):286-92.
2003: Noriyuki Ouchi; Shinji Kihara; Tohru Funahashi; Tadashi Nakamura; Makoto Nishida; Masahiro Kumada; Yoshihisa Okamoto; Koji Ohashi; Hiroyuki Nagaretani; Ken Kishida; Hitoshi Nishizawa; Norikazu Maeda; Hideki Kobayashi; Hisatoyo Hiraoka; Yuji Matsuzawa
Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue.
Circulation 2003;107(5):671-4.
2003: Yuji Matsuzawa; Iichiro Shimomura; Shinji Kihara; Tohru Funahashi
Importance of adipocytokines in obesity-related diseases.
Hormone research 2003;60 Suppl 3():56-9.
2003: Masahiro Kumada; Shinji Kihara; Satoru Sumitsuji; Toshiharu Kawamoto; Satoru Matsumoto; Noriyuki Ouchi; Yukio Arita; Yoshihisa Okamoto; Iichiro Shimomura; Hisatoyo Hiraoka; Tadashi Nakamura; Tohru Funahashi; Yuji Matsuzawa
Association of hypoadiponectinemia with coronary artery disease in men.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(1):85-9.
2002: Yoshihisa Okamoto; Shinji Kihara; Noriyuki Ouchi; Makoto Nishida; Yukio Arita; Masahiro Kumada; Koji Ohashi; Naohiko Sakai; Iichiro Shimomura; Hideki Kobayashi; Naoki Terasaka; Toshimori Inaba; Tohru Funahashi; Yuji Matsuzawa
Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice.
Circulation 2002;106(22):2767-70.
2002: Azumi Nagasawa; K Fukui; Tohru Funahashi; Norikazu Maeda; Iichiro Shimomura; Shinji Kihara; M Waki; K Takamatsu; Yuji Matsuzawa
Effects of soy protein diet on the expression of adipose genes and plasma adiponectin.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(11-12):635-9.
2002: Morihiro Matsuda; Iichiro Shimomura; Masataka Sata; Yukio Arita; Makoto Nishida; Norikazu Maeda; Masahiro Kumada; Yoshihisa Okamoto; Hiroyuki Nagaretani; Hitoshi Nishizawa; Ken Kishida; Ryutaro Komuro; Noriyuki Ouchi; Shinji Kihara; Ryozo Nagai; Tohru Funahashi; Yuji Matsuzawa
Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis.
The Journal of biological chemistry 2002;277(40):37487-91.
2002: Hiroshi Kuriyama; Iichiro Shimomura; Ken Kishida; Hidehiko Kondo; Naoki Furuyama; Hitoshi Nishizawa; Norikazu Maeda; Morihiro Matsuda; Hiroyuki Nagaretani; Shinji Kihara; Tadashi Nakamura; Yoshihiro Tochino; Tohru Funahashi; Yuji Matsuzawa
Coordinated regulation of fat-specific and liver-specific glycerol channels, aquaporin adipose and aquaporin 9.
Diabetes 2002;51(10):2915-21.
2002: Hitoshi Nishizawa; Iichiro Shimomura; Ken Kishida; Norikazu Maeda; Hiroshi Kuriyama; Hiroyuki Nagaretani; Morihiro Matsuda; Hidehiko Kondo; Naoki Furuyama; Shinji Kihara; Tadashi Nakamura; Yoshihiro Tochino; Tohru Funahashi; Yuji Matsuzawa
Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein.
Diabetes 2002;51(9):2734-41.
2002: Akihisa Imagawa; Tohru Funahashi; Tadashi Nakamura; Makoto Moriwaki; Sachiyo Tanaka; Hitoshi Nishizawa; Kouichi Sayama; Sae Uno; Hiromi Iwahashi; Kazuya Yamagata; Jun-ichiro Miyagawa; Yuji Matsuzawa
Elevated serum concentration of adipose-derived factor, adiponectin, in patients with type 1 diabetes.
Diabetes care 2002;25(9):1665-6.
2002: Tohru Funahashi; Yuji Matsuzawa
[Adiponectin as a key molecule of the metabolic syndrome].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 7():583-92.
2002: Hidehiko Kondo; Iichiro Shimomura; Yuko Matsukawa; Masahiro Kumada; Masahiko Takahashi; Morihiro Matsuda; Noriyuki Ouchi; Shinji Kihara; Toshiharu Kawamoto; Satoru Sumitsuji; Tohru Funahashi; Yuji Matsuzawa
Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome.
Diabetes 2002;51(7):2325-8.
2002: Norikazu Maeda; Iichiro Shimomura; Ken Kishida; Hitoshi Nishizawa; Morihiro Matsuda; Hiroyuki Nagaretani; Naoki Furuyama; Hidehiko Kondo; Masahiko Takahashi; Yukio Arita; Ryutaro Komuro; Noriyuki Ouchi; Shinji Kihara; Yoshihiro Tochino; Keiichi Okutomi; Masato Horie; Satoshi Takeda; Toshifumi Aoyama; Tohru Funahashi; Yuji Matsuzawa
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30.
Nature medicine 2002;8(7):731-7.
2002: Yukio Arita; Shinji Kihara; Noriyuki Ouchi; Kazuhisa Maeda; Hiroshi Kuriyama; Yoshihisa Okamoto; Masahiro Kumada; Kikuko Hotta; Makoto Nishida; Masahiko Takahashi; Tadashi Nakamura; Iichiro Shimomura; Masahiro Muraguchi; Yasukazu Ohmoto; Tohru Funahashi; Yuji Matsuzawa
Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell.
Circulation 2002;105(24):2893-8.
2002: Satoru Matsumoto; Ken Kishida; Iichiro Shimomura; Norikazu Maeda; Hiroyuki Nagaretani; Morihiro Matsuda; Hitoshi Nishizawa; Shinji Kihara; Tohru Funahashi; Yuji Matsuzawa; Akira Yamada; Shizuya Yamashita; Shinji Tamura; Sumio Kawata
Increased plasma HB-EGF associated with obesity and coronary artery disease.
Biochemical and biophysical research communications 2002;292(3):781-6.
2002: Hidehiko Kondo; Iichiro Shimomura; Ken Kishida; Hiroshi Kuriyama; Yasunaka Makino; Hitoshi Nishizawa; Morihiro Matsuda; Norikazu Maeda; Hiroyuki Nagaretani; Shinji Kihara; Yoshihisa Kurachi; Tadashi Nakamura; Tohru Funahashi; Yuji Matsuzawa
Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation.
European journal of biochemistry / FEBS 2002;269(7):1814-26.
2002: Hitoshi Nishizawa; Kazuya Yamagata; Iichiro Shimomura; Masahiko Takahashi; Hiroshi Kuriyama; Ken Kishida; Kikuko Hotta; Hiroyuki Nagaretani; Norikazu Maeda; Morihiro Matsuda; Shinji Kihara; Tadashi Nakamura; Hidekazu Nishigori; Hideaki Tomura; David D Moore; Jun Takeda; Tohru Funahashi; Yuji Matsuzawa
Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation.
The Journal of biological chemistry 2002;277(2):1586-92.
2002: Yuji Matsuzawa; Tohru Funahashi; Tadashi Nakamura
Molecular mechanism of vascular disease in metabolic syndrome X.
Journal of diabetes and its complications 2002;16(1):17-8.
2001: Ken Kishida; Iichiro Shimomura; Hitoshi Nishizawa; Norikazu Maeda; Hiroshi Kuriyama; Hidehiko Kondo; Morihiro Matsuda; Hiroyuki Nagaretani; Noriyuki Ouchi; Kikuko Hotta; Shinji Kihara; Takashi Kadowaki; Tohru Funahashi; Yuji Matsuzawa
Enhancement of the aquaporin adipose gene expression by a peroxisome proliferator-activated receptor gamma.
The Journal of biological chemistry 2001;276(51):48572-9.
2001: Hiroyuki Nagaretani; Tadashi Nakamura; Tohru Funahashi; K Kotani; M Miyanaga; K Tokunaga; Masahiko Takahashi; Hitoshi Nishizawa; Ken Kishida; Hiroshi Kuriyama; Kikuko Hotta; Shizuya Yamashita; Yuji Matsuzawa
Visceral fat is a major contributor for multiple risk factor clustering in Japanese men with impaired glucose tolerance.
Diabetes care 2001;24(12):2127-33.
2001: Tadashi Nakamura; Tohru Funahashi; Shizuya Yamashita; M Nishida; Y Nishida; Masahiko Takahashi; Kikuko Hotta; Hiroshi Kuriyama; Shinji Kihara; N Ohuchi; Tsunehiko Nishimura; B I Kishino; K Ishikawa; T Kawamoto; K Tokunaga; C Nakagawa; Ikuo Mineo; F Watanabe; Seiichiro Tarui; Yuji Matsuzawa
Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation--double-blind placebo-controlled trial.
Diabetes research and clinical practice 2001;54(3):181-90.
2001: Ken Kishida; Iichiro Shimomura; Hidehiko Kondo; Hiroshi Kuriyama; Y Makino; Hitoshi Nishizawa; Norikazu Maeda; Morihiro Matsuda; Noriyuki Ouchi; Shinji Kihara; Yoshihisa Kurachi; Tohru Funahashi; Yuji Matsuzawa
Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel.
The Journal of biological chemistry 2001;276(39):36251-60.
2001: Kikuko Hotta; Tohru Funahashi; Y Matsukawa; Masahiko Takahashi; Hitoshi Nishizawa; Ken Kishida; Morihiro Matsuda; Hiroshi Kuriyama; Shinji Kihara; Tadashi Nakamura; Yoshihiro Tochino; Noni L Bodkin; Barbara C Hansen; Yuji Matsuzawa
Galectin-12, an Adipose-expressed Galectin-like Molecule Possessing Apoptosis-inducing Activity.
The Journal of biological chemistry 2001;276(36):34089-97.
2001: Norikazu Maeda; Masahiko Takahashi; Tohru Funahashi; Shinji Kihara; Hitoshi Nishizawa; Ken Kishida; Hiroyuki Nagaretani; Morihiro Matsuda; Ryutaro Komuro; Noriyuki Ouchi; Hiroshi Kuriyama; Kikuko Hotta; Tadashi Nakamura; Iichiro Shimomura; Yuji Matsuzawa
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein.
Diabetes 2001;50(9):2094-9.
2001: M Takahashi; Hiroyuki Nagaretani; Tohru Funahashi; Hitoshi Nishizawa; N Maeda; Ken Kishida; Hiroshi Kuriyama; Iichiro Shimomura; K Maeda; Kikuko Hotta; Noriyuki Ouchi; Shinji Kihara; T Nakamura; S Yamashita; Y Matsuzawa
The expression of SPARC in adipose tissue and its increased plasma concentration in patients with coronary artery disease.
Obesity research 2001;9(7):388-93.
2001: Kikuko Hotta; Tohru Funahashi; Noni L Bodkin; Heidi K Ortmeyer; Yukio Arita; Barbara C Hansen; Yuji Matsuzawa
Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys.
Diabetes 2001;50(5):1126-33.
2001: H Kobayashi; Tadashi Nakamura; K Miyaoka; Makoto Nishida; Tohru Funahashi; Shizuya Yamashita; Yuji Matsuzawa
Visceral fat accumulation contributes to insulin resistance, small-sized low-density lipoprotein, and progression of coronary artery disease in middle-aged non-obese Japanese men.
Japanese circulation journal 2001;65(3):193-9.
2001: Noriyuki Ouchi; Shinji Kihara; Yukio Arita; Makoto Nishida; Akifumi Matsuyama; Yoshihisa Okamoto; Masato Ishigami; Hiroshi Kuriyama; Ken Kishida; Hitoshi Nishizawa; Kikuko Hotta; Masahiro Muraguchi; Yasukazu Ohmoto; Shizuya Yamashita; Tohru Funahashi; Yuji Matsuzawa
Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages.
Circulation 2001;103(8):1057-63.
2001: K Kishida; H Kuriyama; Tohru Funahashi; Yuji Matsuzawa
[Molecular mechanism of energy regulation in adipose tissues].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 2():483-8.
2001: Tadashi Nakamura; Y Tsubono; K Kameda-Takemura; Tohru Funahashi; Shizuya Yamashita; S Hisamichi; T Kita; T Yamamura; Yuji Matsuzawa
Magnitude of sustained multiple risk factors for ischemic heart disease in Japanese employees: a case-control study.
Japanese circulation journal 2001;65(1):11-7.
2000: Noriyuki Ouchi; Shinji Kihara; Yukio Arita; Yoshihisa Okamoto; Kazuhisa Maeda; Hiroshi Kuriyama; Kikuko Hotta; Makoto Nishida; Masahiko Takahashi; Masahiro Muraguchi; Yasukazu Ohmoto; Tadashi Nakamura; Shizuya Yamashita; Tohru Funahashi; Yuji Matsuzawa
Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway.
Circulation 2000;102(11):1296-301.
2000: Takashi Yokota; Kenji Oritani; Ichiro Takahashi; Jun Ishikawa; Akifumi Matsuyama; Noriyuki Ouchi; Shinji Kihara; Tohru Funahashi; A J Tenner; Yoshiaki Tomiyama; Yuji Matsuzawa
Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages.
Blood 2000;96(5):1723-32.
2000: Ken Kishida; Hiroshi Kuriyama; Tohru Funahashi; Iichiro Shimomura; Shinji Kihara; Noriyuki Ouchi; Makoto Nishida; Hitoshi Nishizawa; Morihiro Matsuda; Masahiko Takahashi; Kikuko Hotta; Tadashi Nakamura; Shizuya Yamashita; Yoshihiro Tochino; Yuji Matsuzawa
Aquaporin adipose, a putative glycerol channel in adipocytes.
The Journal of biological chemistry 2000;275(27):20896-902.
2000: Masahiko Takahashi; Yukio Arita; Kazuya Yamagata; Y Matsukawa; K Okutomi; Masato Horie; Iichiro Shimomura; Kikuko Hotta; Hiroshi Kuriyama; Shinji Kihara; Tadashi Nakamura; Shizuya Yamashita; Tohru Funahashi; Yuji Matsuzawa
Genomic structure and mutations in adipose-specific gene, adiponectin.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(7):861-8.
2000: Kikuko Hotta; Tohru Funahashi; Yukio Arita; Masahiko Takahashi; Morihiro Matsuda; Yoshihisa Okamoto; Hiromi Iwahashi; Hiroshi Kuriyama; Noriyuki Ouchi; Kazuhisa Maeda; Makoto Nishida; Shinji Kihara; Norio Sakai; T Nakajima; K Hasegawa; Masahiro Muraguchi; Yasukazu Ohmoto; Tadashi Nakamura; Shizuya Yamashita; T Hanafusa; Yuji Matsuzawa
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(6):1595-9.
2000: Ryutaro Komuro; Shizuya Yamashita; Satoru Sumitsuji; Kenichi Hirano; T Maruyama; Makoto Nishida; Fumihiko Matsuura; Akifumi Matsuyama; T Sugimoto; Noriyuki Ouchi; Naohiko Sakai; Tadashi Nakamura; Tohru Funahashi; Yuji Matsuzawa
Tangier disease with continuous massive and longitudinal diffuse calcification in the coronary arteries : demonstration by the sagittal images of intravascular ultrasonography.
Circulation 2000;101(20):2446-8.
2000: Yoshihisa Okamoto; Yukio Arita; Makoto Nishida; Masahiro Muraguchi; Noriyuki Ouchi; Masahiko Takahashi; Takumi Igura; Yoshiaki Inui; Shinji Kihara; Tadashi Nakamura; Shizuya Yamashita; Jun-ichiro Miyagawa; Tohru Funahashi; Yuji Matsuzawa
An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2000;32(2):47-50.
2000: K Hotta; Y Matsukawa; Makoto Nishida; K Kotani; Masahiko Takahashi; H Kuriyama; Tadashi Nakamura; K Wada; Shizuya Yamashita; Tohru Funahashi; Yuji Matsuzawa
Mutation in bombesin receptor subtype-3 gene is not a major cause of obesity in the Japanese.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2000;32(1):33-4.
1999: Noriyuki Ouchi; Shinji Kihara; Yukio Arita; Kazuhisa Maeda; Hiroshi Kuriyama; Yoshihisa Okamoto; Kikuko Hotta; Makoto Nishida; Masahiko Takahashi; Tadashi Nakamura; Shizuya Yamashita; Tohru Funahashi; Yuji Matsuzawa
Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin.
Circulation 1999;100(25):2473-6.
1999: Yuji Matsuzawa; Tohru Funahashi; Tadashi Nakamura
Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances.
Annals of the New York Academy of Sciences 1999;892():146-54.
1999: Yukio Arita; Shinji Kihara; Noriyuki Ouchi; Masahiko Takahashi; Kazuhisa Maeda; Jun-ichiro Miyagawa; Kikuko Hotta; Iichiro Shimomura; Tadashi Nakamura; K Miyaoka; Hiroshi Kuriyama; Makoto Nishida; Shizuya Yamashita; K Okubo; K Matsubara; Masahiro Muraguchi; Yasukazu Ohmoto; Tohru Funahashi; Yuji Matsuzawa
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity.
Biochemical and biophysical research communications 1999;257(1):79-83.
1999: Tohru Funahashi; Tadashi Nakamura; Iichiro Shimomura; Kazuhisa Maeda; Hiroshi Kuriyama; Masahiko Takahashi; Yukio Arita; Shinji Kihara; Yuji Matsuzawa
Role of adipocytokines on the pathogenesis of atherosclerosis in visceral obesity.
Internal medicine (Tokyo, Japan) 1999;38(2):202-6.
1999: Fumihiko Matsuura; Shizuya Yamashita; Kenichi Hirano; Masato Ishigami; Hisatoyo Hiraoka; R Tamura; T Nakagawa; Makoto Nishida; Norio Sakai; Tadashi Nakamura; S Nozaki; Tohru Funahashi; C Matsumoto; M Higashiyama; K Yoshikawa; Yuji Matsuzawa
Activation of monocytes in vivo causes intracellular accumulation of lipoprotein-derived lipids and marked hypocholesterolemia--a possible pathogenesis of necrobiotic xanthogranuloma.
Atherosclerosis 1999;142(2):355-65.
1998: T Nakagawa; S Nozaki; Makoto Nishida; J M Yakub; Yoshiaki Tomiyama; A Nakata; Kunihiro Matsumoto; Tohru Funahashi; K Kameda-Takemura; Yoshiyuki Kurata; Shizuya Yamashita; Yuji Matsuzawa
Oxidized LDL increases and interferon-gamma decreases expression of CD36 in human monocyte-derived macrophages.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(8):1350-7.
1998: Fumihiko Matsuura; Shizuya Yamashita; Tadashi Nakamura; Makoto Nishida; S Nozaki; Tohru Funahashi; Yuji Matsuzawa
Effect of visceral fat accumulation on uric acid metabolism in male obese subjects: visceral fat obesity is linked more closely to overproduction of uric acid than subcutaneous fat obesity.
Metabolism: clinical and experimental 1998;47(8):929-33.
1998: E Shinohara; Shinji Kihara; Noriyuki Ouchi; Tohru Funahashi; Tadashi Nakamura; Shizuya Yamashita; K Kameda-Takemura; Yuji Matsuzawa
Troglitazone suppresses intimal formation following balloon injury in insulin-resistant Zucker fatty rats.
Atherosclerosis 1998;136(2):275-9.
1998: Hiroshi Kuriyama; Shizuya Yamashita; Iichiro Shimomura; Tohru Funahashi; Masato Ishigami; K Aragane; K Miyaoka; Tadashi Nakamura; K Takemura; Zhi-Wei Man; K Toide; N Nakayama; Yutaka Fukuda; M C Lin; J R Wetterau; Yuji Matsuzawa
Enhanced expression of hepatic acyl-coenzyme A synthetase and microsomal triglyceride transfer protein messenger RNAs in the obese and hypertriglyceridemic rat with visceral fat accumulation.
Hepatology (Baltimore, Md.) 1998;27(2):557-62.
1998: Shinji Kihara; Noriyuki Ouchi; Tohru Funahashi; E Shinohara; R Tamura; Shizuya Yamashita; Yuji Matsuzawa
Troglitazone enhances glucose uptake and inhibits mitogen-activated protein kinase in human aortic smooth muscle cells.
Atherosclerosis 1998;136(1):163-8.
1997: Noriyuki Ouchi; Shinji Kihara; S Yamashita; S Higashiyama; Takatoshi Nakagawa; I Shimomura; Tohru Funahashi; K Kameda-Takemura; Sumio Kawata; Naoyuki Taniguchi; Yuji Matsuzawa
Role of membrane-anchored heparin-binding epidermal growth factor-like growth factor and CD9 on macrophages.
The Biochemical journal 1997;328 ( Pt 3)():923-8.
1997: K Kotani; M Nishida; Shizuya Yamashita; Tohru Funahashi; S Fujioka; K Tokunaga; K Ishikawa; Seiichiro Tarui; Yuji Matsuzawa
Two decades of annual medical examinations in Japanese obese children: do obese children grow into obese adults?
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1997;21(10):912-21.
1997: K Yanagi; Shizuya Yamashita; Shinji Kihara; Tadashi Nakamura; S Nozaki; Yoji Nagai; Tohru Funahashi; K Kameda-Takemura; Y Ueyama; S Jiao; M Kubo; K Tokunaga; Yuji Matsuzawa
Characteristics of coronary artery disease and lipoprotein abnormalities in patients with heterozygous familial hypercholesterolemia associated with diabetes mellitus or impaired glucose tolerance.
Atherosclerosis 1997;132(1):43-51.
1997: Tadashi Nakamura; H Kobayashi; K Yanagi; Tsutomu Nakagawa; M Nishida; Shinji Kihara; Hisatoyo Hiraoka; S Nozaki; Tohru Funahashi; Shizuya Yamashita; K Kameda-Takemura; Yuji Matsuzawa
Importance of intra-abdominal visceral fat accumulation to coronary atherosclerosis in heterozygous familial hypercholesterolaemia.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1997;21(7):580-6.
1997: K Yanagi; Shizuya Yamashita; Hisatoyo Hiraoka; Masato Ishigami; Shinji Kihara; Kenichi Hirano; Norio Sakai; S Nozaki; Tohru Funahashi; K Kameda-Takemura; M Kubo; K Tokunaga; Yuji Matsuzawa
Increased serum remnant lipoproteins in patients with apolipoprotein E7 (apo E Suita).
Atherosclerosis 1997;131(1):49-58.
1996: M Takahashi; Tohru Funahashi; Iichiro Shimomura; K Miyaoka; Yuji Matsuzawa
Plasma leptin levels and body fat distribution.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1996;28(12):751-2.
1996: T Arai; S Yamashita; Norio Sakai; Kenichi Hirano; Shintaro Okada; Masato Ishigami; Takao Maruyama; M Yamane; H Kobayashi; S Nozaki; Tohru Funahashi; K Kameda-Takemura; N Nakajima; Yuji Matsuzawa
A novel nonsense mutation (G181X) in the human cholesteryl ester transfer protein gene in Japanese hyperalphalipoproteinemic subjects.
Journal of lipid research 1996;37(10):2145-54.
1996: Iichiro Shimomura; Tohru Funahashi; M Takahashi; K Maeda; K Kotani; Tadashi Nakamura; S Yamashita; M Miura; Y Fukuda; K Takemura; K Tokunaga; Yuji Matsuzawa
Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity.
Nature medicine 1996;2(7):800-3.
1996: Iichiro Shimomura; M Takahashi; K Tokunaga; Y Keno; Tadashi Nakamura; S Yamashita; K Takemura; T Yamamoto; Tohru Funahashi; Yuji Matsuzawa
Rapid enhancement of acyl-CoA synthetase, LPL, and GLUT-4 mRNAs in adipose tissue of VMH rats.
The American journal of physiology 1996;270(6 Pt 1):E995-1002.
1996: K Maeda; K Okubo; Iichiro Shimomura; Tohru Funahashi; Yuji Matsuzawa; K Matsubara
cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1).
Biochemical and biophysical research communications 1996;221(2):286-9.
1996: Tohru Funahashi; S Yamashita; T Maruyama; Y Ueyama; M Menju; Y Nagai; K Takemura; Y Miyake; S Tajima; Yuji Matsuzawa
A compound heterozygote for familial hypercholesterolaemia with a homozygous mother.
Journal of internal medicine 1996;239(2):187-90.
1995: Tohru Funahashi; Iichiro Shimomura; Hisatoyo Hiraoka; T Arai; M Takahashi; Tadashi Nakamura; S Nozaki; S Yamashita; K Takemura; K Tokunaga
Enhanced expression of rat obese (ob) gene in adipose tissues of ventromedial hypothalamus (VMH)-lesioned rats.
Biochemical and biophysical research communications 1995;211(2):469-75.
1995: Norio Sakai; S Yamashita; Kenichi Hirano; Masato Ishigami; T Arai; K Kobayashi; Tohru Funahashi; Yuji Matsuzawa
Decreased affinity of low density lipoprotein (LDL) particles for LDL receptors in patients with cholesteryl ester transfer protein deficiency.
European journal of clinical investigation 1995;25(5):332-9.
1995: T Nakagawa; Y Ueyama; S Nozaki; S Yamashita; M Menju; Tohru Funahashi; K Kameda-Takemura; M Kubo; K Tokunaga; T Tanaka
Marked hypocholesterolemia in a case with adrenal adenoma--enhanced catabolism of low density lipoprotein (LDL) via the LDL receptors of tumor cells.
The Journal of clinical endocrinology and metabolism 1995;80(1):92-6.
1993: Norio Sakai; S Yamashita; Y Ueyama; T Kawamoto; Tadashi Nakamura; Tohru Funahashi; K Kameda-Takemura; Sumio Kawata; M Kubo; K Tokunaga
Extralysosomal degradation of high-density lipoproteins in a human hepatoma cell line, Mahlavu.
Biochimica et biophysica acta 1993;1169(2):169-75.
1993: Iichiro Shimomura; K Tokunaga; K Kotani; Y Keno; M Yanase-Fujiwara; Kazuyuki Kanosue; S Jiao; Tohru Funahashi; T Kobatake; T Yamamoto
Marked reduction of acyl-CoA synthetase activity and mRNA in intra-abdominal visceral fat by physical exercise.
The American journal of physiology 1993;265(1 Pt 1):E44-50.
1993: Kenichi Hirano; S Yamashita; Tohru Funahashi; Norio Sakai; M Menju; Masato Ishigami; Hisatoyo Hiraoka; K Kameda-Takemura; K Tokunaga; T Hoshino
Frequency of intron 14 splicing defect of cholesteryl ester transfer protein gene in the Japanese general population--relation between the mutation and hyperalphalipoproteinemia.
Atherosclerosis 1993;100(1):85-90.
1992: Kenichi Hirano; Yuji Matsuzawa; Norio Sakai; Hisatoyo Hiraoka; S Nozaki; Tohru Funahashi; S Yamashita; M Kubo; S Tarui
Polydisperse low-density lipoproteins in hyperalphalipoproteinemic chronic alcohol drinkers in association with marked reduction of cholesteryl ester transfer protein activity.
Metabolism: clinical and experimental 1992;41(12):1313-8.
1992: Kenichi Hirano; S Yamashita; Norio Sakai; Hisatoyo Hiraoka; Y Ueyama; Tohru Funahashi; Yuji Matsuzawa
Low-density lipoproteins in hyperalphalipoproteinemic heavy alcohol drinkers have reduced affinity for the low-density lipoprotein receptor.
Clinical biochemistry 1992;25(5):357-62.
1992: S Nozaki; Iichiro Shimomura; Tohru Funahashi; M Menju; M Kubo; Yuji Matsuzawa
Stimulation of the activity and mRNA level of hepatic triacylglycerol lipase by triiodothyronine in HepG2 cells.
Biochimica et biophysica acta 1992;1127(3):298-302.
1992: Iichiro Shimomura; K Tokunaga; S Jiao; Tohru Funahashi; Y Keno; T Kobatake; K Kotani; H Suzuki; T Yamamoto; S Tarui
Marked enhancement of acyl-CoA synthetase activity and mRNA, paralleled to lipoprotein lipase mRNA, in adipose tissues of Zucker obese rats (fa/fa).
Biochimica et biophysica acta 1992;1124(2):112-8.
1992: Tadashi Nakamura; Y Ueyama; Tohru Funahashi; S Yamashita; K K Takemura; M Kubo; K Yamada; Yuji Matsuzawa
Non-macrophage-related accumulation of cholesterol during probucol treatment in familial hypercholesterolemia: report of two cases.
Atherosclerosis 1992;92(2-3):193-202.
1990: Y Ueyama; Yuji Matsuzawa; S Yamashita; Tohru Funahashi; Norio Sakai; Tadashi Nakamura; M Kubo; S Tarui
Hypocholesterolaemic factor from gallbladder cancer cells.
Lancet 1990;336(8717):707-9.
1989: Shinji Kihara; Yuji Matsuzawa; M Kubo; S Nozaki; Tohru Funahashi; S Yamashita; N Sho; S Tarui
Autoimmune hyperchylomicronemia.
The New England journal of medicine 1989;320(19):1255-9.
1988: T Nakajima; Tadashi Nakamura; Tohru Funahashi; H Kanai; Y Kurata; Yuji Matsuzawa; S Tarui
A novel system of LDL apheresis combining a centrifugal plasma separator with a specific LDL adsorption column.
Atherosclerosis 1988;73(2-3):143-8.
1988: Yuji Matsuzawa; S Yamashita; Tohru Funahashi; A Yamamoto; S Tarui
Selective reduction of cholesterol in HDL2 fraction by probucol in familial hypercholesterolemia and hyperHDL2 cholesterolemia with abnormal cholesteryl ester transfer.
The American journal of cardiology 1988;62(3):66B-72B.
1988: Tadashi Nakamura; Yuji Matsuzawa; M Okano; Y Kitano; Tohru Funahashi; S Yamashita; S Tarui
Characterization of low-density lipoproteins from patients with recessive X-linked ichthyosis.
Atherosclerosis 1988;70(1-2):43-52.
1987: S Yamashita; T Kawamoto; Y Ueyama; Tohru Funahashi; H Hara; K Hirobe; Yuji Matsuzawa; A Yamamoto; S Tarui
Relationship between LDL receptor activity and development of coronary heart disease in Japanese cases with heterozygous familial hypercholesterolemia.
Artery 1987;15(1):24-43.