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Kenji Funami

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Hiroyuki Oshiumi; Hussein H Aly; Kenji Funami; Misako Matsumoto; Tsukasa Seya
Multi-step regulation of interferon induction by hepatitis C virus.
Misako Matsumoto; Hiroyuki Oshiumi; Kenji Funami; Tsukasa Seya
Toll-IL-1-Receptor-Containing Adaptor Molecule-1: A Signaling Adaptor Linking Innate Immunity to Adaptive Immunity.
Miwa Sasai; Megumi Tatematsu; Hiroyuki Oshiumi; Kenji Funami; Misako Matsumoto; Shigetsugu Hatakeyama; Tsukasa Seya
Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway.

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All Publications

2013: Hiroyuki Oshiumi; Hussein H Aly; Kenji Funami; Misako Matsumoto; Tsukasa Seya
Multi-step regulation of interferon induction by hepatitis C virus.
Archivum immunologiae et therapiae experimentalis 2013;61(2):127-38.
2013: Misako Matsumoto; Hiroyuki Oshiumi; Kenji Funami; Tsukasa Seya
Toll-IL-1-Receptor-Containing Adaptor Molecule-1: A Signaling Adaptor Linking Innate Immunity to Adaptive Immunity.
Progress in molecular biology and translational science 2013;117():487-510.
2010: Miwa Sasai; Megumi Tatematsu; Hiroyuki Oshiumi; Kenji Funami; Misako Matsumoto; Shigetsugu Hatakeyama; Tsukasa Seya
Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway.
Molecular immunology 2010;47(6):1283-91.
2008: Kiyoharu Itoh; Ayako Watanabe; Kenji Funami; Tsukasa Seya; Misako Matsumoto
The clathrin-mediated endocytic pathway participates in dsRNA-induced IFN-beta production.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5522-9.
2008: Masashi Shingai; Masahiro Azuma; Takashi Ebihara; Miwa Sasai; Kenji Funami; Minoru Ayata; Hisashi Ogura; Hiroyuki Tsutsumi; Misako Matsumoto; Tsukasa Seya
Soluble G protein of respiratory syncytial virus inhibits Toll-like receptor 3/4-mediated IFN-beta induction.
International immunology 2008;20(9):1169-80.
2008: Kenji Funami; Miwa Sasai; Hiroyuki Oshiumi; Tsukasa Seya; Misako Matsumoto
Homo-oligomerization is essential for Toll/interleukin-1 receptor domain-containing adaptor molecule-1-mediated NF-kappaB and interferon regulatory factor-3 activation.
The Journal of biological chemistry 2008;283(26):18283-91.
2008: Megumi Higuchi; Aya Matsuo; Masashi Shingai; Kyoko Shida; Akihiro Ishii; Kenji Funami; Yasuhiko Suzuki; Hiroyuki Oshiumi; Misako Matsumoto; Tsukasa Seya
Combinational recognition of bacterial lipoproteins and peptidoglycan by chicken Toll-like receptor 2 subfamily.
Developmental and comparative immunology 2008;32(2):147-55.
2007: Kenji Funami; Miwa Sasai; Yusuke Ohba; Hiroyuki Oshiumi; Tsukasa Seya; Misako Matsumoto
Spatiotemporal mobilization of Toll/IL-1 receptor domain-containing adaptor molecule-1 in response to dsRNA.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6867-72.
2007: Eiko Takada; Satoyo Okahira; Miwa Sasai; Kenji Funami; Tsukasa Seya; Misako Matsumoto
C-terminal LRRs of human Toll-like receptor 3 control receptor dimerization and signal transmission.
Molecular immunology 2007;44(15):3633-40.
2006: Miwa Sasai; Masashi Shingai; Kenji Funami; Mitsutoshi Yoneyama; Takashi Fujita; Misako Matsumoto; Tsukasa Seya
NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8676-83.
2005: Kenji Funami; Tsukasa Seya
[Immunologic tests: CR3 (Mac-1, CD11b/CD18), CR4 (CD11c/CD18)].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 7():71-3.
2005: Junji Uehori; Koichi Fukase; Takashi Akazawa; Satoshi Uematsu; Shizuo Akira; Kenji Funami; Masashi Shingai; Misako Matsumoto; Ichiro Azuma; Kumao Toyoshima; Shoichi Kusumoto; Tsukasa Seya
Dendritic cell maturation induced by muramyl dipeptide (MDP) derivatives: monoacylated MDP confers TLR2/TLR4 activation.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7096-103.
2005: Yoshiya Nakao; Kenji Funami; Satomi Kikkawa; Mitsue Taniguchi; Miyuki Nishiguchi; Yasuo Fukumori; Tsukasa Seya; Misako Matsumoto
Surface-expressed TLR6 participates in the recognition of diacylated lipopeptide and peptidoglycan in human cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1566-73.
2005: Tsukasa Seya; Kenji Funami; Mitsue Taniguchi; Misako Matsumoto
Antibodies against human Toll-like receptors (TLRs): TLR distribution and localization in human dendritic cells.
Journal of endotoxin research 2005;11(6):369-74.
2004: Kenji Funami; Misako Matsumoto; Hiroyuki Oshiumi; Takashi Akazawa; Akitsugu Yamamoto; Tsukasa Seya
The cytoplasmic 'linker region' in Toll-like receptor 3 controls receptor localization and signaling.
International immunology 2004;16(8):1143-54.
2004: Misako Matsumoto; Kenji Funami; Hiroyuki Oshiumi; Tsukasa Seya
Toll-like receptor 3: a link between toll-like receptor, interferon and viruses.
Microbiology and immunology 2004;48(3):147-54.
2003: Misako Matsumoto; Kenji Funami; Masako Tanabe; Hiroyuki Oshiumi; Masashi Shingai; Yoshiyuki Seto; Akitsugu Yamamoto; Tsukasa Seya
Subcellular localization of Toll-like receptor 3 in human dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):3154-62.
2003: Hiroyuki Oshiumi; Misako Matsumoto; Kenji Funami; Takashi Akazawa; Tsukasa Seya
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction.
Nature immunology 2003;4(2):161-7.