Man-Lung Fung

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Jia Xiao; Emily C Liong; Ming-Tat Ling; Yick-Pang Ching; Man-Lung Fung; George L Tipoe
S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice.
Siu-Yin Lam; Yu Liu; Kwong-Man Ng; Chi-Fai Lau; Emily C Liong; George L Tipoe; Man-Lung Fung
Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways.
Kwong-Man Ng; Yau-Chi Chan; Yee-Ki Lee; Wing-Hon Lai; Ka-Wing Au; Man-Lung Fung; Chung-Wah Siu; Ronald A Li; Hung-Fat Tse
Cobalt chloride pretreatment promotes cardiac differentiation of human embryonic stem cells under atmospheric oxygen level.

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All Publications

2012: Jia Xiao; Emily C Liong; Ming-Tat Ling; Yick-Pang Ching; Man-Lung Fung; George L Tipoe
S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice.
European journal of nutrition 2012;51(3):323-33.
2012: Siu-Yin Lam; Yu Liu; Kwong-Man Ng; Chi-Fai Lau; Emily C Liong; George L Tipoe; Man-Lung Fung
Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways.
Histochemistry and cell biology 2012;137(3):303-17.
2011: Kwong-Man Ng; Yau-Chi Chan; Yee-Ki Lee; Wing-Hon Lai; Ka-Wing Au; Man-Lung Fung; Chung-Wah Siu; Ronald A Li; Hung-Fat Tse
Cobalt chloride pretreatment promotes cardiac differentiation of human embryonic stem cells under atmospheric oxygen level.
Cellular reprogramming 2011;13(6):527-37.
2011: Tung-Ming Leung; Man-Lung Fung; Emily C Liong; Thomas Y H Lau; Amin A Nanji; George L Tipoe
Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice.
Histology and histopathology 2011;26(2):201-11.
2011: Kwong-Man Ng; Yee-Ki Lee; Wing-Hon Lai; Yau-Chi Chan; Man-Lung Fung; Hung-Fat Tse; Chung-Wah Siu
Exogenous expression of human apoA-I enhances cardiac differentiation of pluripotent stem cells.
PloS one 2011;6(5):e19787.
2011: King-Tung Ng; Jing-Ping Li; Kwong Man Ng; George L Tipoe; W Keung Leung; Man-Lung Fung
Expression of hypoxia-inducible factor-1α in human periodontal tissue.
Journal of periodontology 2011;82(1):136-41.
2010: Kwong-Man Ng; Chi-Fai Lau; Man-Lung Fung
Melatonin reduces hippocampal beta-amyloid generation in rats exposed to chronic intermittent hypoxia.
Brain research 2010;1354():163-71.
2010: Kwong-Man Ng; Yee-Ki Lee; Yau-Chi Chan; Wing-Hon Lai; Man-Lung Fung; Ronald A Li; Chung-Wah Siu; Hung-Fat Tse
Exogenous expression of HIF-1 alpha promotes cardiac differentiation of embryonic stem cells.
Journal of molecular and cellular cardiology 2010;48(6):1129-37.
2009: G L Tipoe; C T Ho; E C Liong; T M Leung; T Y H Lau; M L Fung; A A Nanji
Voluntary oral feeding of rats not requiring a very high fat diet is a clinically relevant animal model of non-alcoholic fatty liver disease (NAFLD).
Histology and histopathology 2009;24(9):1161-9.
2009: S Y Lam; G L Tipoe; M L Fung
Upregulation of erythropoietin and its receptor expression in the rat carotid body during chronic and intermittent hypoxia.
Advances in experimental medicine and biology 2009;648():207-14.
2008: H M Yeung; M W Hung; M L Fung
Melatonin ameliorates calcium homeostasis in myocardial and ischemia-reperfusion injury in chronically hypoxic rats.
Journal of pineal research 2008;45(4):373-82.
2008: Jiangang Shen; Waisin Lee; Yue Li; Chi Fai Lau; Kwong Man Ng; Man Lung Fung; Ke Jian Liu
Interaction of caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells.
Journal of neurochemistry 2008;107(2):478-87.
2008: Siu-Yin Lam; George L Tipoe; Emily C Liong; Man-Lung Fung
Chronic hypoxia upregulates the expression and function of proinflammatory cytokines in the rat carotid body.
Histochemistry and cell biology 2008;130(3):549-59.
2008: Tung-Ming Leung; George L Tipoe; Emily C Liong; Thomas Y H Lau; Man-Lung Fung; Amin A Nanji
Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis.
International journal of experimental pathology 2008;89(4):241-50.
2008: Y W Tjong; M F Li; M W Hung; M L Fung
Melatonin ameliorates hippocampal nitric oxide production and large conductance calcium-activated potassium channel activity in chronic intermittent hypoxia.
Journal of pineal research 2008;44(3):234-43.
2008: Ming-Wai Hung; George L Tipoe; Angela Ming-See Poon; Russel J Reiter; Man-Lung Fung
Protective effect of melatonin against hippocampal injury of rats with intermittent hypoxia.
Journal of pineal research 2008;44(2):214-21.
2008: Siu-Yin Lam; George L Tipoe; Emily C Liong; Man-Lung Fung
Differential expressions and roles of hypoxia-inducible factor-1alpha, -2alpha and -3alpha in the rat carotid body during chronic and intermittent hypoxia.
Histology and histopathology 2008;23(3):271-80.
2008: Yung-Wui Tjong; Meifang Li; Ming-Wai Hung; Kun Wang; Man-Lung Fung
Nitric oxide deficit in chronic intermittent hypoxia impairs large conductance calcium-activated potassium channel activity in rat hippocampal neurons.
Free radical biology & medicine 2008;44(4):547-57.
2007: Kuihuan Jian; Ming Chen; Xiong Cao; Xin-Hong Zhu; Man-Lung Fung; Tian-Ming Gao
Nitric oxide modulation of voltage-gated calcium current by S-nitrosylation and cGMP pathway in cultured rat hippocampal neurons.
Biochemical and biophysical research communications 2007;359(3):481-5.
2007: George L Tipoe; Tung-Ming Leung; Ming-Wai Hung; Man-Lung Fung
Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection.
Cardiovascular & hematological disorders drug targets 2007;7(2):135-44.
2007: Hang Mee Yeung; Gennadi M Kravtsov; Kwong Man Ng; Tak Ming Wong; Man Lung Fung
Chronic intermittent hypoxia alters Ca2+ handling in rat cardiomyocytes by augmented Na+/Ca2+ exchange and ryanodine receptor activities in ischemia-reperfusion.
American journal of physiology. Cell physiology 2007;292(6):C2046-56.
2007: Man-Lung Fung; Siu-Yin Lam; Tung-Po Wong; Yung-Wui Tjong; Po-Sing Leung
Carotid Body AT(4) Receptor Expression and its Upregulation in Chronic Hypoxia.
The open cardiovascular medicine journal 2007;1():1-7.
2007: Man-Lung Fung; Meifang Li; Sukhamay Lahiri
Increased endogenous nitric oxide release by iron chelation and purinergic activation in the rat carotid body.
The open biochemistry journal 2007;1():1-6.
2007: Isabel S S Hwang; Man Lung Fung; Emily C Liong; George L Tipoe; Fai Tang
Age-related changes in adrenomedullin expression and hypoxia-inducible factor-1 activity in the rat lung and their responses to hypoxia.
The journals of gerontology. Series A, Biological sciences and medical sciences 2007;62(1):41-9.
2007: Yung-Wui Tjong; Kuihuan Jian; Meifang Li; Ming Chen; Tian-Ming Gao; Man-Lung Fung
Elevated endogenous nitric oxide increases Ca2+ flux via L-type Ca2+ channels by S-nitrosylation in rat hippocampal neurons during severe hypoxia and in vitro ischemia.
Free radical biology & medicine 2007;42(1):52-63.
2006: G L Tipoe; T M Leung; E Liong; H So; K M Leung; T Y H Lau; W M Tom; M L Fung; S T Fan; A A Nanji
Inhibitors of inducible nitric oxide (NO) synthase are more effective than an NO donor in reducing carbon-tetrachloride induced acute liver injury.
Histology and histopathology 2006;21(11):1157-65.
2006: George L Tipoe; Thomas Y-H Lau; Amin A Nanji; Man-Lung Fung
Expression and functions of vasoactive substances regulated by hypoxia-inducible factor-1 in chronic hypoxemia.
Cardiovascular & hematological agents in medicinal chemistry 2006;4(3):199-218.
2006: Yung-Wui Tjong; Yueping Chen; Emily C Liong; George L Tipoe; Man-Lung Fung
Chronic hypoxia modulates the function and expression of melatonin receptors in the rat carotid body.
Journal of pineal research 2006;40(2):125-34.
2006: Siu-Yin Lam; Emily C Liong; George L Tipoe; Man-Lung Fung
Expression of HIF-2alpha and HIF-3alpha in the rat carotid body in chronic hypoxia.
Advances in experimental medicine and biology 2006;580():29-36; discussion 351-9.
2006: Siu-Yin Lam; George L Tipoe; Emily C Liong; Man-Lung Fung
Hypoxia-inducible factor (HIF)-1alpha and endothelin-1 expression in the rat carotid body during intermittent hypoxia.
Advances in experimental medicine and biology 2006;580():21-7; discussion 351-9.
2005: Yueping Chen; Yung-Wui Tjong; Shing-Fat Ip; George L Tipoe; Man-Lung Fung
Melatonin enhances the hypoxic response of rat carotid body chemoreceptor.
Journal of pineal research 2005;38(3):157-63.
2004: Siu Yin Lam; Man-Lung Fung; Po Sing Leung
Regulation of the angiotensin-converting enzyme activity by a time-course hypoxia in the carotid body.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(2):809-13.
2004: Yung Wui Tjong; Yueping Chen; Emily C Liong; Shing Fat Ip; George L Tipoe; Man Lung Fung
Melatonin attenuates rat carotid chemoreceptor response to hypercapnic acidosis.
Journal of pineal research 2004;36(1):49-57.
2003: Jian-Ming Pei; Gennadi M Kravtsov; Song Wu; Rapti Das; Man Lung Fung; Tak Ming Wong
Calcium homeostasis in rat cardiomyocytes during chronic hypoxia: a time course study.
American journal of physiology. Cell physiology 2003;285(6):C1420-8.
2003: George L Tipoe; Man-Lung Fung
Expression of HIF-1alpha, VEGF and VEGF receptors in the carotid body of chronically hypoxic rat.
Respiratory physiology & neurobiology 2003;138(2-3):143-54.
2003: Man-Lung Fung
Hypoxia-inducible factor-1: a molecular hint of physiological changes in the carotid body during long-term hypoxemia?
Current drug targets. Cardiovascular & haematological disorders 2003;3(3):254-9.
2003: Po Sing Leung; Man Lung Fung; Michael S C Tam
Renin-angiotensin system in the carotid body.
The international journal of biochemistry & cell biology 2003;35(6):847-54.
2003: Man-Lung Fung; George L Tipoe
Role of HIF-1 in physiological adaptation of the carotid body during chronic hypoxia.
Advances in experimental medicine and biology 2003;536():593-601.
2002: Tian-Ming Gao; Man-Lung Fung
Decreased large conductance Ca(2+)-activated K(+) channel activity in dissociated CA1 hippocampal neurons in rats exposed to perinatal and postnatal hypoxia.
Neuroscience letters 2002;332(3):163-6.
2002: Jian-Shan Ye; George L Tipoe; Peter C W Fung; Man-Lung Fung
Augmentation of hypoxia-induced nitric oxide generation in the rat carotid body adapted to chronic hypoxia: an involvement of constitutive and inducible nitric oxide synthases.
Pflügers Archiv : European journal of physiology 2002;444(1-2):178-85.
2002: Jian Shan; Xiao-Chun Yu; Man-Lung Fung; Tak-Ming Wong
Attenuated "cross talk" between kappa-opioid receptors and beta-adrenoceptors in the heart of chronically hypoxic rats.
Pflügers Archiv : European journal of physiology 2002;444(1-2):126-32.
2002: Man-Lung Fung; Hung-Yu Li; Tak-Ming Wong
Forskolin fails to activate L-type calcium current in hypertrophied cardiomyocytes of chronically hypoxic rats.
Life sciences 2002;70(15):1801-9.
2002: Yueping Chen; George L Tipoe; Emily Liong; Sing Leung; Siu-Yin Lam; Ryu Iwase; Yung-Wui Tjong; Man-Lung Fung
Chronic hypoxia enhances endothelin-1-induced intracellular calcium elevation in rat carotid body chemoreceptors and up-regulates ETA receptor expression.
Pflügers Archiv : European journal of physiology 2002;443(4):565-73.
2001: M L Fung; X Dong
Absence of MK801-induced inspiratory prolongation in chronically hypoxic rats.
Life sciences 2001;69(19):2319-26.
2001: M L Fung; J S Ye; P C Fung
Acute hypoxia elevates nitric oxide generation in rat carotid body in vitro.
Pflügers Archiv : European journal of physiology 2001;442(6):903-9.
2001: M L Fung; S Y Lam; Y Chen; X Dong; P S Leung
Functional expression of angiotensin II receptors in type-I cells of the rat carotid body.
Pflügers Archiv : European journal of physiology 2001;441(4):474-80.
2000: P S Leung; S Y Lam; M L Fung
Chronic hypoxia upregulates the expression and function of AT(1) receptor in rat carotid body.
The Journal of endocrinology 2000;167(3):517-24.
2000: J M Pei; J J Zhou; J S Bian; X C Yu; M L Fung; T M Wong
Impaired [Ca(2+)](i) and pH(i) responses to kappa-opioid receptor stimulation in the heart of chronically hypoxic rats.
American journal of physiology. Cell physiology 2000;279(5):C1483-94.
2000: J M Pei; X C Yu; M L Fung; J J Zhou; C S Cheung; N S Wong; M P Leung; T M Wong
Impaired G(s)alpha and adenylyl cyclase cause beta-adrenoceptor desensitization in chronically hypoxic rat hearts.
American journal of physiology. Cell physiology 2000;279(5):C1455-63.
2000: M L Fung
Role of voltage-gated Na+ channels in hypoxia-induced neuronal injuries.
Clinical and experimental pharmacology & physiology 2000;27(8):569-74.
2000: W P Chan; M L Fung; R Nobiling; P S Leung
Activation of local renin-angiotensin system by chronic hypoxia in rat pancreas.
Molecular and cellular endocrinology 2000;160(1-2):107-14.
1999: M L Fung; M D Croning; G G Haddad
Sodium homeostasis in rat hippocampal slices during oxygen and glucose deprivation: role of voltage-sensitive sodium channels.
Neuroscience letters 1999;275(1):41-4.
1998: M L Fung; W M St John
Pontine cholinergic respiratory depression in neonatal and young rats.
Life sciences 1998;62(24):2249-56.
1997: M L Fung; Q Huang; D Zhou; W M St John
The morphology and connections of neurons in the gasping centre of adult rats.
Neuroscience 1997;76(4):1237-44.
1996: D Zhou; Q Huang; M L Fung; A Li; R A Darnall; E E Nattie; W M St John
Phrenic response to hypercapnia in the unanesthetized, decerbrate, newborn rat.
Respiration physiology 1996;104(1):11-22.
1996: M L Fung; W Wang; R A Darnall; W M St John
Characterization of ventilatory responses to hypoxia in neonatal rats.
Respiration physiology 1996;103(1):57-66.
1996: W Wang; M L Fung; R A Darnall; W M St John
Characterizations and comparisons of eupnoea and gasping in neonatal rats.
The Journal of physiology 1996;490 ( Pt 1)():277-92.
1995: M L Fung; W M St John
The functional expression of a pontine pneumotaxic centre in neonatal rats.
The Journal of physiology 1995;489 ( Pt 2)():579-91.
1995: Z Tomori; M L Fung; V Donic; V Donicova; W M St John
Power spectral analysis of respiratory responses to pharyngeal stimulation in cats: comparisons with eupnoea and gasping.
The Journal of physiology 1995;485 ( Pt 2)():551-9.
1995: M L Fung; Z Tomori; W M St John
Medullary neuronal activities in gasping induced by pharyngeal stimulation and hypoxia.
Respiration physiology 1995;100(3):195-202.
1995: M L Fung; W M St John
Expiratory neural activities in gasping induced by pharyngeal stimulation and hypoxia.
Respiration physiology 1995;100(2):119-27.
1994: M L Fung; W M St John
Neuronal activities underlying inspiratory termination by pneumotaxic mechanisms.
Respiration physiology 1994;98(3):267-81.
1994: M L Fung; W Wang; W M St John
Medullary loci critical for expression of gasping in adult rats.
The Journal of physiology 1994;480 ( Pt 3)():597-611.
1994: M L Fung; W Wang; W M St John
Involvement of pontile NMDA receptors in inspiratory termination in rat.
Respiration physiology 1994;96(2-3):177-88.
1994: M L Fung; W M St John
Separation of multiple functions in ventilatory control of pneumotaxic mechanisms.
Respiration physiology 1994;96(1):83-98.
1994: M L Fung; W M St John
Electrical stimulation of pneumotaxic center: activation of fibers and neurons.
Respiration physiology 1994;96(1):71-82.
1994: M L Fung; W M St John; Z Tomori
Reflex recruitment of medullary gasping mechanisms in eupnoea by pharyngeal stimulation in cats.
The Journal of physiology 1994;475(3):519-29.
1993: E E Nattie; M L Fung; A Li; W M St John
Responses of respiratory modulated and tonic units in the retrotrapezoid nucleus to CO2.
Respiration physiology 1993;94(1):35-50.
1993: W Wang; M L Fung; W M St John
Pontile regulation of ventilatory activity in the adult rat.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(6):2801-11.