FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Koichi Furukawa

Research Profile

Chemicals & Drugs

Living Beings

Concepts & Ideas

Molecular Sequence Data

Physiology

Anatomy

Co-author Network

Publications

TOP 3
Yuji Kondo; Yoshio Kuroki; Kensuke Miyake; Chiaki Nishitani; Umeharu Ohto; Ryo Taguchi; Noriyo Tokuda; Makoto Uchikawa; Qing Zhang; Sachiko Akashi-Takamura; Keiko Furukawa; Kazutaka Ikeda; Yasutomo Ito; Koichi Furukawa
TLR4-MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide.
Maiko Kurosawa; Eva-Maria Surmann; Vignesh Venkatraman; Ashok R Venkitaraman; Koichi Furukawa; Noboru Hashimoto; Anand D Jeyasekharan; Gene Kurosawa; Yoshikazu Kurosawa
Expression of LY6D is induced at the surface of MCF10A cells by X-ray irradiation.
Koichi Furukawa; Kazunori Hamamura; Yuki Ohkawa; Yuhsuke Ohmi; Keiko Furukawa
Disialyl gangliosides enhance tumor phenotypes with differential modalities.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Koichi Furukawa (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Yuji Kondo; Yoshio Kuroki; Kensuke Miyake; Chiaki Nishitani; Umeharu Ohto; Ryo Taguchi; Noriyo Tokuda; Makoto Uchikawa; Qing Zhang; Sachiko Akashi-Takamura; Keiko Furukawa; Kazutaka Ikeda; Yasutomo Ito; Koichi Furukawa
TLR4-MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(12):4714-9.
2012: Maiko Kurosawa; Eva-Maria Surmann; Vignesh Venkatraman; Ashok R Venkitaraman; Koichi Furukawa; Noboru Hashimoto; Anand D Jeyasekharan; Gene Kurosawa; Yoshikazu Kurosawa
Expression of LY6D is induced at the surface of MCF10A cells by X-ray irradiation.
The FEBS journal 2012;279(24):4479-91.
2012: Koichi Furukawa; Kazunori Hamamura; Yuki Ohkawa; Yuhsuke Ohmi; Keiko Furukawa
Disialyl gangliosides enhance tumor phenotypes with differential modalities.
Glycoconjugate journal 2012;29(8-9):579-84.
2012: Noboru Hashimoto; Koichi Honke; Kei Kaneko; Norihiro Kotani; Keiko Furukawa; Kazunori Hamamura; Koichi Furukawa
Proteomic analysis of ganglioside-associated membrane molecules: substantial basis for molecular clustering.
Proteomics 2012;12(21):3154-63.
2012: Hidenobu Shibuya; Minoru Ueda; Keiko Furukawa; Kazunori Hamamura; Hisashi Hattori; Hiroshi Hotta; Yasuyuki Matsumoto; Yoshihiro Nishida; Koichi Furukawa
Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3.
Cancer science 2012;103(9):1656-64.
2012: Koichi Furukawa; Kazunori Hamamura; Yuki Ohkawa; Yuhsuke Ohmi; Yoshio Yamauchi; Keiko Furukawa
Fine tuning of cell signals by glycosylation.
Journal of biochemistry 2012;151(6):573-8.
2012: Yuhsuke Ohmi; Orie Tajima; Yoshio Yamauchi; Keiko Furukawa; Yuki Ohkawa; Koichi Furukawa
Essential roles of gangliosides in the formation and maintenance of membrane microdomains in brain tissues.
Neurochemical research 2012;37(6):1185-91.
2012: Yuta Sakaidani; Chika Saito; Koichi Furukawa; Naoki Ichiyanagi; Makiko Ito; Tsukasa Matsuda; Daita Nadano; Yosuke Nishio; Tomoko Nomura; Tetsuya Okajima
O-linked-N-acetylglucosamine modification of mammalian Notch receptors by an atypical O-GlcNAc transferase Eogt1.
Biochemical and biophysical research communications 2012;419(1):14-9.
2012: Yasuyuki Matsumoto; Hiroshi Nakada; Tetsuya Okajima; Noriyo Tokuda; Akiko Tsuchida; Takeshi Urano; Qing Zhang; Keiko Furukawa; Kazunori Hamamura; Tomoko Hori; Takeshi Matsubara; Kaoru Akita; Koichi Furukawa
pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen.
Biochemical and biophysical research communications 2012;419(1):7-13.
2011: Koei Hayashi; Kiyomi Hori; Kazunori Itoh; Kenji Kawakita; Kazue Mizumura; Noriyuki Ozaki; Takeshi Yamaguchi; Masaya Yasui; Shuang-Qin Yi; Koichi Furukawa; Yasuo Sugiura
Involvement of NGF in the rat model of persistent muscle pain associated with taut band.
The journal of pain : official journal of the American Pain Society 2011;12(10):1059-68.
2011: Koichi Furukawa; Yuji Kondo; Yuki Ohkawa; Yuhsuke Ohmi; Orie Tajima; Noriyo Tokuda; Keiko Furukawa
Regulatory mechanisms of nervous systems with glycosphingolipids.
Neurochemical research 2011;36(9):1578-86.
2011: Yuki Ohkawa; Yuhsuke Ohmi; Orie Tajima; Yoshio Yamauchi; Keiko Furukawa; Koichi Furukawa
Wisp2/CCN5 up-regulated in the central nervous system of GM3-only mice facilitates neurite formation in Neuro2a cells via integrin-Akt signaling.
Biochemical and biophysical research communications 2011;411(3):483-9.
2011: Xiaoyan Fan; Keiko Furukawa; Reiko Ando; Koji Kikkawa; Yuji Kondo; Hisashi Narimatsu; Yuhsuke Ohmi; Tetsuya Okajima; Kiyosumi Shibata; Akira Togayachi; Noriyo Tokuda; Tomokazu Umezu; Qing Zhang; Koichi Furukawa
Strong antibody reaction against glycosphingolipids injected in liposome-embedded forms in beta3GN-T5 knockout mice.
Nagoya journal of medical science 2011;73(3-4):137-46.
2011: Yuji Kondo; Noriyo Tokuda; Makoto Uchikawa; Fan Xiaoyan; Qing Zhang; Reiko Ando; Keiko Furukawa; Koichi Furukawa
Efficient generation of useful monoclonal antibodies reactive with globotriaosylceramide using knockout mice lacking Gb3/CD77 synthase.
Glycoconjugate journal 2011;28(6):371-84.
2011: Koichi Furukawa; Yuhsuke Ohmi; Yuki Ohkawa; Noriyo Tokuda; Orie Tajima; Keiko Furukawa
[Molecular mechanisms for the regulation of nervous systems with glycosphingolipids].
Seikagaku. The Journal of Japanese Biochemical Society 2011;83(3):169-78.
2011: Yuhsuke Ohmi; Orie Tajima; Yuki Ohkawa; Yoshio Yamauchi; Yasuo Sugiura; Keiko Furukawa; Koichi Furukawa
Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice.
Journal of neurochemistry 2011;116(5):926-35.
2011: Yukihisa Hamaguchi; Yasushi Tatematsu; Koichi Furukawa; Tatsuaki Matsubara; Shinsuke Nakayama
Imipramine inhibition of TRPM-like plasmalemmal Mg2+ transport in vascular smooth muscle cells.
Journal of cellular and molecular medicine 2011;15(3):593-601.
2010: Koichi Furukawa; Kazunori Hamamura; Yuki Ohkawa; Keiko Furukawa
[Drug discovery sciences in Japan with focus on molecular-targeted drugs].
Nihon rinsho. Japanese journal of clinical medicine 2010;68(10):1797-802.
2010: Yu Dong; Kazutaka Ikeda; Kazunori Hamamura; Qing Zhang; Yuji Kondo; Yasuyuki Matsumoto; Yuhsuke Ohmi; Yoshio Yamauchi; Keiko Furukawa; Ryo Taguchi; Koichi Furukawa
GM1 / GD1b / GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line.
Cancer science 2010;101(9):2039-47.
2010: Yuki Ohkawa; Sayaka Miyazaki; Kazunori Hamamura; Mariko Kambe; Maiko Miyata; Orie Tajima; Yuhsuke Ohmi; Yoshio Yamauchi; Koichi Furukawa; Keiko Furukawa
Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains.
The Journal of biological chemistry 2010;285(35):27213-23.
2010: Orie Tajima; Nobuaki Egashira; Yuhsuke Ohmi; Yoshihiko Fukue; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara; Yasuo Sugiura; Keiko Furukawa; Koichi Furukawa
Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice.
Behavioural brain research 2010;206(1):101-8.
2009: Yuhsuke Ohmi; Orie Tajima; Yuki Ohkawa; Atsushi Mori; Yasuo Sugiura; Keiko Furukawa; Koichi Furukawa
Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(52):22405-10.
2009: Koichi Furukawa; Akiko Tsuchida; Tetsuya Okajima; Keiko Furukawa
Glycoconjugate glycosyltransferases.
Glycoconjugate journal 2009;26(8):987-98.
2009: Orie Tajima; Nobuaki Egashira; Yuhsuke Ohmi; Yoshihiko Fukue; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara; Jinichi Inokuchi; Yasuo Sugiura; Keiko Furukawa; Koichi Furukawa
Reduced motor and sensory functions and emotional response in GM3-only mice: emergence from early stage of life and exacerbation with aging.
Behavioural brain research 2009;198(1):74-82.
2009: Yuji Kondo; Noriyo Tokuda; Xiayan Fan; Tatsuyuki Yamashita; Koichi Honke; Hiromu Takematsu; Hiroshi Takematsu; Akira Togayachi; Michio Ohta; Yasunori Kotzusumi; Hisashi Narimatsu; Orie Tajima; Koichi Furukawa; Keiko Furukaw; Koichi Furukawa
Glycosphingolipids are not pivotal receptors for Subtilase cytotoxin in vivo: sensitivity analysis with glycosylation-defective mutant mice.
Biochemical and biophysical research communications 2009;378(2):179-81.
2008: Aiko Matsuura; Makiko Ito; Yuta Sakaidani; Tatsuhiko Kondo; Kosuke Murakami; Koichi Furukawa; Daita Nadano; Tsukasa Matsuda; Tetsuya Okajima
O-linked N-acetylglucosamine is present on the extracellular domain of notch receptors.
The Journal of biological chemistry 2008;283(51):35486-95.
2008: Yuko Fujii; Noriyuki Ozaki; Toru Taguchi; Kazue Mizumura; Koichi Furukawa; Yasuo Sugiura
TRP channels and ASICs mediate mechanical hyperalgesia in models of inflammatory muscle pain and delayed onset muscle soreness.
Pain 2008;140(2):292-304.
2008: Yuki Ohkawa; Sayaka Miyazaki; Maiko Miyata; Kazunori Hamamura; Koichi Furukawa; Keiko Furukawa
Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3.
Biochemical and biophysical research communications 2008;373(1):14-9.
2008: Yingsong Zhu; Akiko Tsuchida; Akihito Yamamoto; Keiko Furukawa; Orie Tajima; Noriyo Tokuda; Shinichi Aizawa; Takeshi Urano; Kenji Kadomatsu; Koichi Furukawa
Expression and roles of a xenopus head-forming gene homologue in human cancer cell lines.
Nagoya journal of medical science 2008;70(3-4):73-82.
2008: Koichi Furukawa; Kazunori Hamamura; Hideyuki Nakashima; Keiko Furukawa
Molecules in the signaling pathway activated by gangliosides can be targets of therapeutics for malignant melanomas.
Proteomics 2008;8(16):3312-6.
2008: Daiji Kittaka; Michi-ichirou Itoh; Yuhsuke Ohmi; Yuji Kondo; Satoshi Fukumoto; Takeshi Urano; Orie Tajima; Keiko Furukawa; Koichi Furukawa
Impaired hypoglossal nerve regeneration in mutant mice lacking complex gangliosides: down-regulation of neurotrophic factors and receptors as possible mechanisms.
Glycobiology 2008;18(7):509-16.
2008: Yukihisa Hamaguchi; Tatsuaki Matsubara; Tetsuya Amano; Tadayuki Uetani; Haruhiko Asano; Takashi Iwamoto; Koichi Furukawa; Toyoaki Murohara; Shinsuke Nakayama
Na(+)-independent Mg(2+) transport sensitive to 2-aminoethoxydiphenyl borate (2-APB) in vascular smooth muscle cells: involvement of TRPM-like channels.
Journal of cellular and molecular medicine 2008;12(3):962-74.
2008: Keiko Furukawa; Wei Aixinjueluo; Takeshi Kasama; Yuki Ohkawa; Michiko Yoshihara; Yusuke Ohmi; Orie Tajima; Akio Suzumura; Daiji Kittaka; Koichi Furukawa
Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis21.
Journal of neurochemistry 2008;105(3):1057-66.
2008: Kazunori Hamamura; Momoko Tsuji; Yuki Ohkawa; Hideyuki Nakashima; Sayaka Miyazaki; Takeshi Urano; Noriyuki Yamamoto; Minoru Ueda; Koichi Furukawa; Keiko Furukawa
Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells.
Biochimica et biophysica acta 2008;1780(3):513-9.
2007: Akikazu Fujita; Jinglei Cheng; Minako Hirakawa; Koichi Furukawa; Susumu Kusunoki; Toyoshi Fujimoto
Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling.
Molecular biology of the cell 2007;18(6):2112-22.
2007: Hideyuki Nakashima; Kazunori Hamamura; Toshiaki Houjou; Ryo Taguchi; Noriyuki Yamamoto; Kenji Mitsudo; Iwai Tohnai; Minoru Ueda; Takeshi Urano; Keiko Furukawa; Koichi Furukawa
Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.
Cancer science 2007;98(4):512-20.
2007: Motohiro Senda; Akihiro Ito; Akiko Tsuchida; Tomoko Hagiwara; Tsuguhiro Kaneda; Yoko Nakamura; Kenji Kasama; Makoto Kiso; Kazuhiro Yoshikawa; Yoko Katagiri; Yoshinari Ono; Manabu Ogiso; Takeshi Urano; Keiko Furukawa; Shinichi Oshima; Koichi Furukawa
Identification and expression of a sialyltransferase responsible for the synthesis of disialylgalactosylgloboside in normal and malignant kidney cells: downregulation of ST6GalNAc VI in renal cancers.
The Biochemical journal 2007;402(3):459-70.
2007: Tadayuki Uetani; Daisuke Yamashita; Juichiro Shimizu; Hiromi Misawa; Yasushi Tatematsu; Yukihisa Hamaguchi; Takehiro Miyasaka; Yuki Katanosaka; Toshiaki Kato; Tatsuaki Matsubara; Koichi Furukawa; Toyoaki Murohara; Miyako Takaki; Shinsuke Nakayama
Heart slice NMR.
American journal of physiology. Heart and circulatory physiology 2007;292(2):H1181-6.
2006: S Ohashi; G Sakashita; R Ban; M Nagasawa; H Matsuzaki; Y Murata; H Taniguchi; H Shima; Koichi Furukawa; Takeshi Urano
Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies.
Oncogene 2006;25(59):7691-702.
2006: K Ko; Koichi Furukawa; Takashi Takahashi; Takeshi Urano; Y Sanai; Masato Nagino; Yuji Nimura; K Furukawa
Fundamental study of small interfering RNAs for ganglioside GD3 synthase gene as a therapeutic target of lung cancers.
Oncogene 2006;25(52):6924-35.
2006: Koichi Furukawa; Kazunori Hamamura; Wei Aixinjueluo; Keiko Furukawa
Biosignals modulated by tumor-associated carbohydrate antigens: novel targets for cancer therapy.
Annals of the New York Academy of Sciences 2006;1086():185-98.
2006: Noriyo Tokuda; Qing Zhang; Shoko Yoshida; Susumu Kusunoki; Takeshi Urano; Keiko Furukawa; Koichi Furukawa
Genetic mechanisms for the synthesis of fucosyl GM1 in small cell lung cancer cell lines.
Glycobiology 2006;16(10):916-25.
2006: Qing Zhang; Keiko Furukawa; Ho-Hsiang Chen; Reiko Fujinawa; Yasunori Kozutsumi; Akemi Suzuki; Takeshi Urano; Koichi Furukawa
Down-regulation of caveolin-1 in mouse Lewis lung cancer P29 is a causal factor for the malignant properties in a high-metastatic subline.
Oncology reports 2006;16(2):289-94.
2006: Qing Zhang; Keiko Furukawa; Ho-Hsiang Chen; Takumi Sakakibara; Takeshi Urano; Koichi Furukawa
Metastatic potential of mouse Lewis lung cancer cells is regulated via ganglioside GM1 by modulating the matrix metalloprotease-9 localization in lipid rafts.
The Journal of biological chemistry 2006;281(26):18145-55.
2006: Tetsuya Okuda; Noriyo Tokuda; Shin-ichiro Numata; Masafumi Ito; Michio Ohta; Kumiko Kawamura; Joelle Wiels; Takeshi Urano; Orie Tajima; Keiko Furukawa; Koichi Furukawa
Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins.
The Journal of biological chemistry 2006;281(15):10230-5.
2006: Koichi Furukawa; Tetsuya Okuda; Keiko Furukawa
Roles of glycolipids in the development and maintenance of nervous tissues.
Methods in enzymology 2006;417():37-52.
2005: Yuko Fujii; Shin-ichiro Numata; Yoko Nakamura; Takashi Honda; Keiko Furukawa; Takeshi Urano; Joelle Wiels; Makoto Uchikawa; Noriyuki Ozaki; Sei-ichi Matsuo; Yasuo Sugiura; Koichi Furukawa
Murine glycosyltransferases responsible for the expression of globo-series glycolipids: cDNA structures, mRNA expression, and distribution of their products.
Glycobiology 2005;15(12):1257-67.
2005: Yoshihiro Handa; Noriyuki Ozaki; Takashi Honda; Koichi Furukawa; Yasushi Tomita; Masahiro Inoue; Keiko Furukawa; Masahiko Okada; Yasuo Sugiura
GD3 synthase gene knockout mice exhibit thermal hyperalgesia and mechanical allodynia but decreased response to formalin-induced prolonged noxious stimulation.
Pain 2005;117(3):271-9.
2005: Akiko Tsuchida; Manabu Ogiso; Yoko Nakamura; Makoto Kiso; Keiko Furukawa; Koichi Furukawa
Molecular cloning and expression of human ST6GalNAc III: restricted tissue distribution and substrate specificity.
Journal of biochemistry 2005;138(3):237-43.
2005: Wei Aixinjueluo; Keiko Furukawa; Qing Zhang; Kazunori Hamamura; Noriyo Tokuda; Shoko Yoshida; Ryuzo Ueda; Koichi Furukawa
Mechanisms for the apoptosis of small cell lung cancer cells induced by anti-GD2 monoclonal antibodies: roles of anoikis.
The Journal of biological chemistry 2005;280(33):29828-36.
2005: Kazunori Hamamura; Keiko Furukawa; Takanori Hayashi; Takeshi Hattori; Junji Nakano; Hideyuki Nakashima; Tetsuya Okuda; Hideki Mizutani; Hisashi Hattori; Minoru Ueda; Takeshi Urano; Kenneth O Lloyd; Koichi Furukawa
Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):11041-6.
2005: Kazunori Hamamura; Kuniaki Tanahashi; Keiko Furukawa; Takeshi Hattori; Hisashi Hattori; Hideki Mizutani; Minoru Ueda; Takeshi Urano; Koichi Furukawa
GM1 expression in H-ras-transformed NIH3T3 results in the suppression of cell proliferation inducing the partial transfer of activated H-ras from non-raft to raft fraction.
International journal of oncology 2005;26(4):897-904.
2005: Yutaka Kamimura; Keiko Furukawa; Daiji Kittaka; Masashi Nishio; Kazunori Hamamura; Satoshi Fukumoto; Koichi Furukawa
Differential enhancing effects of alpha2,8-sialyltransferase on the cell proliferation and mobility.
International journal of oncology 2005;26(2):337-44.
2005: Yasuo Sugiura; Koichi Furukawa; Orie Tajima; S Mii; Takashi Honda; K Furukawa
Sensory nerve-dominant nerve degeneration and remodeling in the mutant mice lacking complex gangliosides.
Neuroscience 2005;135(4):1167-78.
2005: Masashi Nishio; Orie Tajima; Keiko Furukawa; Takeshi Urano; Koichi Furukawa
Over-expression of GM1 enhances cell proliferation with epidermal growth factor without affecting the receptor localization in the microdomain in PC12 cells.
International journal of oncology 2005;26(1):191-9.
2004: Xiangyu Li; Gyosuke Sakashita; Hideki Matsuzaki; Kenji Sugimoto; Keiji Kimura; Fumio Hanaoka; Hisaaki Taniguchi; Koichi Furukawa; Takeshi Urano
Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C.
The Journal of biological chemistry 2004;279(45):47201-11.
2004: Masashi Nishio; Satoshi Fukumoto; Keiko Furukawa; Akiko Ichimura; Hiroshi Miyazaki; Susumu Kusunoki; Takeshi Urano; Koichi Furukawa
Overexpressed GM1 suppresses nerve growth factor (NGF) signals by modulating the intracellular localization of NGF receptors and membrane fluidity in PC12 cells.
The Journal of biological chemistry 2004;279(32):33368-78.
2004: Koichi Furukawa; Noriyo Tokuda; Tetsuya Okuda; Orie Tajima; Keiko Furukawa
Glycosphingolipids in engineered mice: insights into function.
Seminars in cell & developmental biology 2004;15(4):389-96.
2004: Masashi Nishio; Koichi Furukawa
Incorporation, remodeling and re-expression of exogenous gangliosides in human cancer cell lines in vitro and in vivo.
Nagoya journal of medical science 2004;67(1-2):35-44.
2003: Koji Iwamura; Keiko Furukawa; Makoto Uchikawa; Birgitta Nilsson Sojka; Yoshinao Kojima; Joelle Wiels; Hiroshi Shiku; Takeshi Urano; Koichi Furukawa
The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle.
The Journal of biological chemistry 2003;278(45):44429-38.
2003: Akiko Tsuchida; Toshihide Okajima; Keiko Furukawa; Takayuki Ando; Hideharu Ishida; Aruto Yoshida; Yoko Nakamura; Reiji Kannagi; Makoto Kiso; Koichi Furukawa
Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides.
The Journal of biological chemistry 2003;278(25):22787-94.
2003: Keiko Furukawa; Masato Horie; Kei-ichi Okutomi; Sumio Sugano; Koichi Furukawa
Isolation and functional analysis of the melanoma specific promoter region of human GD3 synthase gene.
Biochimica et biophysica acta 2003;1627(2-3):71-8.
2003: Qian Ma; Miya Kobayashi; Midori Sugiura; Noriyuki Ozaki; Koji Nishio; Yosuke Shiraishi; Keiko Furukawa; Koichi Furukawa; Yasuo Sugiura
Morphological study of disordered myelination and the degeneration of nerve fibers in the spinal cord of mice lacking complex gangliosides.
Archives of histology and cytology 2003;66(1):37-44.
2003: Ho-Hsiang Chen; Satoshi Fukumoto; Keiko Furukawa; Akimasa Nakao; Seiji Akiyama; Takeshi Urano; Koichi Furukawa
Suppression of lung metastasis of mouse Lewis lung cancer P29 with transfection of the ganglioside GM2/GD2 synthase gene.
International journal of cancer. Journal international du cancer 2003;103(2):169-76.
2002: Koichi Furukawa; Toshihide Okajima
Galactosyltransferase I is a gene responsible for progeroid variant of Ehlers-Danlos syndrome: molecular cloning and identification of mutations.
Biochimica et biophysica acta 2002;1573(3):377-81.
2002: Koichi Furukawa; Kogo Takamiya; Keiko Furukawa
Beta1,4-N-acetylgalactosaminyltransferase--GM2/GD2 synthase: a key enzyme to control the synthesis of brain-enriched complex gangliosides.
Biochimica et biophysica acta 2002;1573(3):356-62.
2002: Yoko Nakamura; Nicola Haines; Jihua Chen; Toshihide Okajima; Keiko Furukawa; Takeshi Urano; Pamela Stanley; Kenneth D Irvine; Koichi Furukawa
Identification of a Drosophila gene encoding xylosylprotein beta4-galactosyltransferase that is essential for the synthesis of glycosaminoglycans and for morphogenesis.
The Journal of biological chemistry 2002;277(48):46280-8.
2002: Masahiro Inoue; Yuko Fujii; Keiko Furukawa; Masahiko Okada; Kenji Okumura; Tetsuo Hayakawa; Koichi Furukawa; Yasuo Sugiura
Refractory skin injury in complex knock-out mice expressing only the GM3 ganglioside.
The Journal of biological chemistry 2002;277(33):29881-8.
2002: Shoko Yoshida; Haruhiko Kawaguchi; Shigeki Sato; Ryuzo Ueda; Koichi Furukawa
An anti-GD2 monoclonal antibody enhances apoptotic effects of anti-cancer drugs against small cell lung cancer cells via JNK (c-Jun terminal kinase) activation.
Japanese journal of cancer research : Gann 2002;93(7):816-24.
2002: Sei ichi Taguchi; Kei Honda; Kazumitsu Sugiura; Akio Yamaguchi; Koichi Furukawa; Takeshi Urano
Degradation of human Aurora-A protein kinase is mediated by hCdh1.
FEBS letters 2002;519(1-3):59-65.
2002: Keiichi Sugiyama; Kazumitsu Sugiura; Tomohiro Hara; Kenji Sugimoto; Hiroshi Shima; Kei Honda; Koichi Furukawa; Shunichi Yamashita; Takeshi Urano
Aurora-B associated protein phosphatases as negative regulators of kinase activation.
Oncogene 2002;21(20):3103-11.
2002: Keiko Furukawa; Keiko Yokoyama; Takeyuki Sato; Joelle Wiels; Yutaka Hirayama; Michio Ohta; Koichi Furukawa
Expression of the Gb3/CD77 synthase gene in megakaryoblastic leukemia cells: implication in the sensitivity to verotoxins.
The Journal of biological chemistry 2002;277(13):11247-54.
2002: Teruhiko Mitsuda; Keiko Furukawa; Satoshi Fukumoto; Hiroshi Miyazaki; Takeshi Urano; Koichi Furukawa
Overexpression of ganglioside GM1 results in the dispersion of platelet-derived growth factor receptor from glycolipid-enriched microdomains and in the suppression of cell growth signals.
The Journal of biological chemistry 2002;277(13):11239-46.
2001: Shoko Yoshida; Satoshi Fukumoto; H Kawaguchi; S Sato; Ryuzo Ueda; Koichi Furukawa
Ganglioside G(D2) in small cell lung cancer cell lines: enhancement of cell proliferation and mediation of apoptosis.
Cancer research 2001;61(10):4244-52.
2001: Koichi Furukawa; Kogo Takamiya; Mayumi Okada; M Inoue; Satoshi Fukumoto; K Furukawa
Novel functions of complex carbohydrates elucidated by the mutant mice of glycosyltransferase genes.
Biochimica et biophysica acta 2001;1525(1-2):1-12.
2000: Toshihide Okajima; Yoko Nakamura; Makoto Uchikawa; D B Haslam; Shin-ichiro Numata; Koichi Furukawa; Takeshi Urano; K Furukawa
Expression cloning of human globoside synthase cDNAs. Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase.
The Journal of biological chemistry 2000;275(51):40498-503.
2000: Koichi Furukawa; Koji Iwamura; Makoto Uchikawa; Birgitta Nilsson Sojka; Joelle Wiels; Toshihide Okajima; Takeshi Urano; K Furukawa
Molecular basis for the p phenotype. Identification of distinct and multiple mutations in the alpha 1,4-galactosyltransferase gene in Swedish and Japanese individuals.
The Journal of biological chemistry 2000;275(48):37752-6.
2000: Kei Honda; H Mihara; Y Kato; Akio Yamaguchi; H Tanaka; H Yasuda; Koichi Furukawa; Takeshi Urano
Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway.
Oncogene 2000;19(24):2812-9.
2000: Y Kojima; Satoshi Fukumoto; Koichi Furukawa; Toshihide Okajima; Joelle Wiels; Keiko Yokoyama; Y Suzuki; Takeshi Urano; Michio Ohta; K Furukawa
Molecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipids.
The Journal of biological chemistry 2000;275(20):15152-6.
2000: Toshihide Okajima; Ho-Hsiang Chen; H Ito; Makoto Kiso; T Tai; Koichi Furukawa; Takeshi Urano; K Furukawa
Molecular cloning and expression of mouse GD1alpha/GT1aalpha/GQ1balpha synthase (ST6GalNAc VI) gene.
The Journal of biological chemistry 2000;275(10):6717-23.
2000: Satoshi Fukumoto; Tatsuro Mutoh; T Hasegawa; Hiroshi Miyazaki; Masahiko Okada; G Goto; Koichi Furukawa; Takeshi Urano
GD3 synthase gene expression in PC12 cells results in the continuous activation of TrkA and ERK1/2 and enhanced proliferation.
The Journal of biological chemistry 2000;275(8):5832-8.
2000: Atsushi Kuroiwa; Yoichi Matsuda; Toshihide Okajima; Koichi Furukawa
Assignment of human xylosylprotein beta-1,4-galactosyltransferase gene (B4GALT7) to human chromosome 5q35.2-->q35.3 by in situ hybridization.
Cytogenetics and cell genetics 2000;89(1-2):8-9.
1999: Toshihide Okajima; Satoshi Fukumoto; H Ito; Makoto Kiso; Y Hirabayashi; Takeshi Urano; Koichi Furukawa
Molecular cloning of brain-specific GD1alpha synthase (ST6GalNAc V) containing CAG/Glutamine repeats.
The Journal of biological chemistry 1999;274(43):30557-62.
1999: Toshihide Okajima; Satoshi Fukumoto; Koichi Furukawa; Takeshi Urano
Molecular basis for the progeroid variant of Ehlers-Danlos syndrome. Identification and characterization of two mutations in galactosyltransferase I gene.
The Journal of biological chemistry 1999;274(41):28841-4.
1999: Koichi Furukawa
[Structure and function of the nuclear lamina].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(12 Suppl):1927-34.
1999: Toshihide Okajima; K Yoshida; Takao Kondo; Koichi Furukawa
Human homolog of Caenorhabditis elegans sqv-3 gene is galactosyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans.
The Journal of biological chemistry 1999;274(33):22915-8.
1999: Toshihide Okajima; Satoshi Fukumoto; Hiroshi Miyazaki; H Ishida; Makoto Kiso; Koichi Furukawa; Takeshi Urano; K Furukawa
Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids.
The Journal of biological chemistry 1999;274(17):11479-86.
1999: Satoshi Fukumoto; Hiroshi Miyazaki; G Goto; Takeshi Urano; Koichi Furukawa; K Furukawa
Expression cloning of mouse cDNA of CMP-NeuAc:Lactosylceramide alpha2,3-sialyltransferase, an enzyme that initiates the synthesis of gangliosides.
The Journal of biological chemistry 1999;274(14):9271-6.
1998: Koichi Furukawa; Kogo Takamiya; Satoshi Fukumoto; J Zhao; Masahiko Okada; K Furukawa; Hiroshi Miyazaki
[Function analysis of complex gangliosides by gangliosides-lacking mutant mice].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(16 Suppl):2295-302.
1998: Koichi Furukawa
[Recent advances in the analysis of ganglioside synthesis].
Seikagaku. The Journal of Japanese Biochemical Society 1998;70(7):532-6.
1998: Koichi Furukawa
Recent progress in the analysis of gangliosides biosynthesis.
Nagoya journal of medical science 1998;61(1-2):27-35.
1998: Koichi Furukawa; T Kondo
Identification of the lamina-associated-polypeptide-2-binding domain of B-type lamin.
European journal of biochemistry / FEBS 1998;251(3):729-33.
1997: Hiroshi Miyazaki; Satoshi Fukumoto; Masahiko Okada; T Hasegawa; Koichi Furukawa
Expression cloning of rat cDNA encoding UDP-galactose:GD2 beta1,3-galactosyltransferase that determines the expression of GD1b/GM1/GA1.
The Journal of biological chemistry 1997;272(40):24794-9.
1997: Koichi Furukawa; C Glass; T Kondo
Characterization of the chromatin binding activity of lamina-associated polypeptide (LAP) 2.
Biochemical and biophysical research communications 1997;238(1):240-6.
1997: Naohito Aoki; Tsukasa Matsuda; T Sakiyama; K Iwatsuki; Koichi Furukawa
Species-specific beta-N-acetylgalactosaminylation of serum IgG proteins.
Biochimica et biophysica acta 1997;1334(2-3):207-13.
1996: Koichi Furukawa
[Structure and function of lamin-associated-proteins].
Seikagaku. The Journal of Japanese Biochemical Society 1996;68(11):1721-5.
1995: N Aoki; Koichi Furukawa; K Iwatsuki; A Noda; T Sato; R Nakamura; Tsukasa Matsuda
A bovine IgG heavy chain contains N-acetylgalactosaminylated N-linked sugar chains.
Biochemical and biophysical research communications 1995;210(2):275-80.
1995: Koichi Furukawa; N Panté; U Aebi; Larry Gerace
Cloning of a cDNA for lamina-associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope.
The EMBO journal 1995;14(8):1626-36.
1995: Y Hotta; Koichi Furukawa; S Tabata
Meiosis specific transcription and functional proteins.
Advances in biophysics 1995;31():101-15.
1994: Koichi Furukawa; H Inagaki; Y Hotta
Identification and cloning of an mRNA coding for a germ cell-specific A-type lamin in mice.
Experimental cell research 1994;212(2):426-30.
1994: Koichi Furukawa; H Inagaki; T Naruge; S Tabata; T Tomida; A Yamaguchi; M Yoshikuni; Y Nagahama; Y Hotta
cDNA cloning and functional characterization of a meiosis-specific protein (MNS1) with apparent nuclear association.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1994;2(2):99-113.
1993: Koichi Furukawa; Y Hotta
cDNA cloning of a germ cell specific lamin B3 from mouse spermatocytes and analysis of its function by ectopic expression in somatic cells.
The EMBO journal 1993;12(1):97-106.
1988: A Hiraiwa; T Naoe; Koichi Furukawa; Y Hirabayashi; Tomomitsu Hotta; H Hara; H Shiku; K Yamada
Serological and biochemical characterization of surface antigen expressed on human myeloid cells and identification of six distinct antigen systems.
Acta haematologica 1988;79(2):61-7.