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Martin Fussenegger
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Research Profile (preview)
Anatomy
Living Beings
Physiology
Genes & Molecular Sequences
Chemicals & Drugs
Procedures
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Network (preview)
43
Weber, Wilfried
25
Bailey, James
16
Kelm, Jens
15
Rimann, Markus
15
Fux, Cornelia
13
Daoud-el Baba, Marie
13
Weber, Cornelia
12
Aubel, Dominique
12
Kramer, Beat
11
Keller, Bettina
9
Schlatter, Stefan
9
Djonov, Valentin
8
Mazur, X
8
Link, Nils
7
Malphettes, Laetitia
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All Publications
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2010: Peng Ren-Wang; Guetg Claudio; Tigges Marcel; Fussenegger Martin
The vesicle-trafficking protein munc18b increases the secretory capacity of mammalian cells.
Metabolic engineering 2010;12(1):18-25.
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2009: Weber Wilfried; Fussenegger Martin
The impact of synthetic biology on drug discovery.
Drug discovery today 2009;14(19-20):956-63.
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2009: Tigges Marcel; Fussenegger Martin
Recent advances in mammalian synthetic biology-design of synthetic transgene control networks.
Current opinion in biotechnology 2009;20(4):449-60.
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2009: Christen Erik H; Karlsson Maria; Kämpf Michael M; Weber Cornelia C; Fussenegger Martin; Weber Wilfried
A general strategy for the production of difficult-to-express inducer-dependent bacterial repressor proteins in Escherichia coli.
Protein expression and purification 2009;66(2):158-64.
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2009: Weber Wilfried; Schuetz Marco; Dénervaud Nicolas; Fussenegger Martin
A synthetic metabolite-based mammalian inter-cell signaling system.
Molecular bioSystems 2009;5(7):757-63.
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2009: Gitzinger Marc; Kemmer Christian; El-Baba Marie Daoud; Weber Wilfried; Fussenegger Martin
Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(26):10638-43.
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2009: Weber Wilfried; Lienhart Cédric; Daoud-El Baba Marie; Grass Robert N; Kohler Thomas; Müller Ralph; Stark Wendelin J; Fussenegger Martin
Magnet-guided transduction of mammalian cells and mice using engineered magnetic lentiviral particles.
Journal of biotechnology 2009;141(3-4):118-22.
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2009: Weber Wilfried; Fussenegger Martin
Engineering of synthetic mammalian gene networks.
Chemistry & biology 2009;16(3):287-97.
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2009: Weber Wilfried; Lienhart Cédric; Baba Marie Daoud-El; Fussenegger Martin
A biotin-triggered genetic switch in mammalian cells and mice.
Metabolic engineering 2009;11(2):117-24.
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2009: Weber Wilfried; Luzi Stefan; Karlsson Maria; Sanchez-Bustamante Carlota Diaz; Frey Urs; Hierlemann Andreas; Fussenegger Martin
A synthetic mammalian electro-genetic transcription circuit.
Nucleic acids research 2009;37(4):e33.
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2009: Peng Ren-Wang; Fussenegger Martin
Molecular engineering of exocytic vesicle traffic enhances the productivity of Chinese hamster ovary cells.
Biotechnology and bioengineering 2009;102(4):1170-81.
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2009: Dreesen Imke A J; Lüchinger Norman A; Stark Wendelin J; Fussenegger Martin
Tricalcium phosphate nanoparticles enable rapid purification, increase transduction kinetics, and modify the tropism of mammalian viruses.
Biotechnology and bioengineering 2009;102(4):1197-208.
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2009: Weber Wilfried; Luzi Stefan; Karlsson Maria; Fussenegger Martin
A novel hybrid dual-channel catalytic-biological sensor system for assessment of fruit quality.
Journal of biotechnology 2009;139(4):314-7.
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2009: Tigges Marcel; Marquez-Lago Tatiana T; Stelling Jörg; Fussenegger Martin
A tunable synthetic mammalian oscillator.
Nature 2009;457(7227):309-12.
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2009: Gitzinger Marc; Parsons Juliana; Reski Ralf; Fussenegger Martin
Functional cross-kingdom conservation of mammalian and moss (Physcomitrella patens) transcription, translation and secretion machineries.
Plant biotechnology journal 2009;7(1):73-86.
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2009: Santoro Raffaella; Lienemann Philipp; Fussenegger Martin
Epigenetic engineering of ribosomal RNA genes enhances protein production.
PloS one 2009;4(8):e6653.
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2008: Fluri David A; Kemmer Christian; Daoud-El Baba Marie; Fussenegger Martin
A novel system for trigger-controlled drug release from polymer capsules.
Journal of controlled release : official journal of the Controlled Release Society 2008;131(3):211-9.
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2008: Ehrbar Martin; Schoenmakers Ronald; Christen Erik H; Fussenegger Martin; Weber Wilfried
Drug-sensing hydrogels for the inducible release of biopharmaceuticals.
Nature materials 2008;7(10):800-4.
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2008: Greber David; El-Baba Marie Daoud; Fussenegger Martin
Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch.
Nucleic acids research 2008;36(16):e101.
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2008: Diaz Sanchez-Bustamante Carlota; Kelm Jens Maria; Egermann Marcus; Djonov Valentin; Fussenegger Martin
Ectopic expression of delta FBJ murine osteosarcoma viral oncogene homolog B mediates transdifferentiation of adipose-like spheroids into osteo-like microtissues.
Tissue engineering. Part A 2008;14(8):1377-94.
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2008: Weber Wilfried; Schoenmakers Ronald; Keller Bettina; Gitzinger Marc; Grau Thomas; Daoud-El Baba Marie; Sander Peter; Fussenegger Martin
A synthetic mammalian gene circuit reveals antituberculosis compounds.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):9994-8.
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2008: Mitterberger Michael; Marksteiner Rainer; Margreiter Eva; Pinggera Germar M; Frauscher Ferdinand; Ulmer Hanno; Fussenegger Martin; Bartsch Georg; Strasser Hannes
Myoblast and fibroblast therapy for post-prostatectomy urinary incontinence: 1-year followup of 63 patients.
The Journal of urology 2008;179(1):226-31.
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2008: Mitterberger Michael; Pinggera Germar-Michael; Marksteiner Rainer; Margreiter Eva; Fussenegger Martin; Frauscher Ferdinand; Ulmer Hanno; Hering Steffen; Bartsch Georg; Strasser Hannes
Adult stem cell therapy of female stress urinary incontinence.
European urology 2008;53(1):169-75.
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2008: Gonzalez-Nicolini Valeria; Fussenegger Martin
Adenovirus-mediated transduction of auto- and dual-regulated transgene expression in mammalian cells.
Methods in molecular biology (Clifton, N.J.) 2008;434():221-37.
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2007: Link Nils; Brunner Tobias J; Dreesen Imke A J; Stark Wendelin J; Fussenegger Martin
Inorganic nanoparticles for transfection of mammalian cells and removal of viruses from aqueous solutions.
Biotechnology and bioengineering 2007;98(5):1083-93.
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2007: Weber Wilfried; Link Nils; Aubel Dominique; Weber Cornelia C; Fussenegger Martin
RepTAGs: universal tags for isolation and labeling of proteins, for labeling live mammalian cells and for drug discovery.
Biotechnology and bioengineering 2007;98(6):1276-87.
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2007: Mitterberger Michael; Marksteiner Rainer; Margreiter Eva; Pinggera Germar M; Colleselli Daniela; Frauscher Ferdinand; Ulmer Hanno; Fussenegger Martin; Bartsch Georg; Strasser Hannes
Autologous myoblasts and fibroblasts for female stress incontinence: a 1-year follow-up in 123 patients.
BJU international 2007;100(5):1081-5.
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2007: Weber Wilfried; Kramer Beat P; Fussenegger Martin
A genetic time-delay circuitry in mammalian cells.
Biotechnology and bioengineering 2007;98(4):894-902.
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2007: Fussenegger Martin; Hauser Hansjörg
Protein expression by engineering of yeast, plant and animal cells.
Current opinion in biotechnology 2007;18(5):385-6.
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2007: Weber Wilfried; Fussenegger Martin
Inducible product gene expression technology tailored to bioprocess engineering.
Current opinion in biotechnology 2007;18(5):399-410.
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2007: Fluri David A; Kelm Jens M; Lesage Guillaume; Baba Marie Daoud-El; Fussenegger Martin
InXy and SeXy, compact heterologous reporter proteins for mammalian cells.
Biotechnology and bioengineering 2007;98(3):655-67.
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2007: Strasser H; Marksteiner R; Margreiter E; Mitterberger M; Pinggera G M; Frauscher F; Fussenegger M; Kofler K; Bartsch G
Transurethral ultrasonography-guided injection of adult autologous stem cells versus transurethral endoscopic injection of collagen in treatment of urinary incontinence.
World journal of urology 2007;25(4):385-92.
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2007: Weber Wilfried; Bacchus William; Gruber Franziska; Hamberger Mattia; Fussenegger Martin
A novel vector platform for vitamin H-inducible transgene expression in mammalian cells.
Journal of biotechnology 2007;131(2):150-8.
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2007: Greber David; Fussenegger Martin
Mammalian synthetic biology: engineering of sophisticated gene networks.
Journal of biotechnology 2007;130(4):329-45.
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2007: Strasser Hannes; Marksteiner Rainer; Margreiter Eva; Pinggera Germar Michael; Mitterberger Michael; Frauscher Ferdinand; Ulmer Hanno; Fussenegger Martin; Kofler Kurt; Bartsch Georg
Autologous myoblasts and fibroblasts versus collagen for treatment of stress urinary incontinence in women: a randomised controlled trial.
Lancet 2007;369(9580):2179-86.
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2007: Weber Wilfried; Daoud-El Baba Marie; Fussenegger Martin
Synthetic ecosystems based on airborne inter- and intrakingdom communication.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10435-40.
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2007: Greber David; Fussenegger Martin
Multi-gene engineering: simultaneous expression and knockdown of six genes off a single platform.
Biotechnology and bioengineering 2007;96(5):821-34.
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2007: Werner Nicola Susann; Weber Wilfried; Fussenegger Martin; Geisse Sabine
A gas-inducible expression system in HEK.EBNA cells applied to controlled proliferation studies by expression of p27(Kip1).
Biotechnology and bioengineering 2007;96(6):1155-66.
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2007: Weber Wilfried; Stelling Jörg; Rimann Markus; Keller Bettina; Daoud-El Baba Marie; Weber Cornelia C; Aubel Dominique; Fussenegger Martin
A synthetic time-delay circuit in mammalian cells and mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2643-8.
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2007: Link Nils; Weber Wilfried; Fussenegger Martin
A novel generic dipstick-based technology for rapid and precise detection of tetracycline, streptogramin and macrolide antibiotics in food samples.
Journal of biotechnology 2007;128(3):668-80.
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2007: Kelm Jens M; Moritz Wolfgang; Schmidt Doerthe; Hoerstrup Simon P; Fussenegger Martin
In vitro vascularization of human connective microtissues.
Methods in molecular medicine 2007;140():153-66.
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2007: Frey U; Sanchez-Bustamante C D; Ugniwenko T; Heer F; Sedivy J; Hafizovic S; Roscic B; Fussenegger M; Blau A; Egert U; Hierlemann A
Cell recordings with a CMOS high-density microelectrode array.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2007;2007():167-70.
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2007: Fluri David A; Baba Marie Daoud-El; Fussenegger Martin
Adeno-associated viral vectors engineered for macrolide-adjustable transgene expression in mammalian cells and mice.
BMC biotechnology 2007;7():75.
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2007: Hartenbach Shizuka; Daoud-El Baba Marie; Weber Wilfried; Fussenegger Martin
An engineered L-arginine sensor of Chlamydia pneumoniae enables arginine-adjustable transcription control in mammalian cells and mice.
Nucleic acids research 2007;35(20):e136.
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2007: Weber Wilfried; Bacchus William; Daoud-El Baba Marie; Fussenegger Martin
Vitamin H-regulated transgene expression in mammalian cells.
Nucleic acids research 2007;35(17):e116.
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2007: Weber W; Fussenegger M
Novel gene switches.
Handbook of experimental pharmacology 2007;(178):73-105.
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2006: Malphettes Laetitia; Fussenegger Martin
Impact of RNA interference on gene networks.
Metabolic engineering 2006;8(6):672-83.
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2006: Malphettes Laetitia; Schoenmakers Ronald G; Fussenegger Martin
6-hydroxy-nicotine-inducible multilevel transgene control in mammalian cells.
Metabolic engineering 2006;8(6):543-53.
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2006: Hartenbach Shizuka; Fussenegger Martin
A novel synthetic mammalian promoter derived from an internal ribosome entry site.
Biotechnology and bioengineering 2006;95(4):547-59.
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2006: Gonzalez-Nicolini Valeria; Sanchez-Bustamante Carlota Diaz; Hartenbach Shizuka; Fussenegger Martin
Adenoviral vector platform for transduction of constitutive and regulated tricistronic or triple-transcript transgene expression in mammalian cells and microtissues.
The journal of gene medicine 2006;8(10):1208-22.
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2006: Kelm Jens M; Djonov Valentin; Hoerstrup Simon P; Guenter Christina I; Ittner Lars M; Greve Frauke; Hierlemann Andreas; Sanchez-Bustamante Carlota Diaz; Perriard Jean-Claude; Ehler Elisabeth; Fussenegger Martin
Tissue-transplant fusion and vascularization of myocardial microtissues and macrotissues implanted into chicken embryos and rats.
Tissue engineering 2006;12(9):2541-53.
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2006: Kelm Jens M; Djonov Valentin; Ittner Lars M; Fluri David; Born Walter; Hoerstrup Simon P; Fussenegger Martin
Design of custom-shaped vascularized tissues using microtissue spheroids as minimal building units.
Tissue engineering 2006;12(8):2151-60.
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2006: Malphettes Laetitia; Fussenegger Martin
Improved transgene expression fine-tuning in mammalian cells using a novel transcription-translation network.
Journal of biotechnology 2006;124(4):732-46.
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2006: Weber Wilfried; Fussenegger Martin
Pharmacologic transgene control systems for gene therapy.
The journal of gene medicine 2006;8(5):535-56.
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2006: Weber Wilfried; Link Nils; Fussenegger Martin
A genetic redox sensor for mammalian cells.
Metabolic engineering 2006;8(3):273-80.
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2006: Weber Wilfried; Rimann Markus; Schafroth Therese; Witschi Ulrich; Fussenegger Martin
Design of high-throughput-compatible protocols for microencapsulation, cryopreservation and release of bovine spermatozoa.
Journal of biotechnology 2006;123(2):155-63.
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2006: Sanchez-Bustamante Carlota Diaz; Kelm Jens M; Mitta Barbara; Fussenegger Martin
Heterologous protein production capacity of mammalian cells cultivated as monolayers and microtissues.
Biotechnology and bioengineering 2006;93(1):169-80.
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2006: Kelm Jens M; Ittner Lars M; Born Walter; Djonov Valentin; Fussenegger Martin
Self-assembly of sensory neurons into ganglia-like microtissues.
Journal of biotechnology 2006;121(1):86-101.
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2006: Link Nils; Aubel Corinne; Kelm Jens M; Marty René R; Greber David; Djonov Valentin; Bourhis Jean; Weber Wilfried; Fussenegger Martin
Therapeutic protein transduction of mammalian cells and mice by nucleic acid-free lentiviral nanoparticles.
Nucleic acids research 2006;34(2):e16.
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2005: Gonzalez-Nicolini Valeria; Fussenegger Martin
A novel binary adenovirus-based dual-regulated expression system for independent transcription control of two different transgenes.
The journal of gene medicine 2005;7(12):1573-85.
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2005: Mitta Barbara; Weber Cornelia C; Fussenegger Martin
In vivo transduction of HIV-1-derived lentiviral particles engineered for macrolide-adjustable transgene expression.
The journal of gene medicine 2005;7(11):1400-8.
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2005: Hartenbach Shizuka; Fussenegger Martin
Autoregulated, bidirectional and multicistronic gas-inducible mammalian as well as lentiviral expression vectors.
Journal of biotechnology 2005;120(1):83-98.
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2005: Carrondo Manuel; Fussenegger Martin
Advances in heterologous protein production.
Journal of biotechnology 2005;120(1):1.
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2005: Mitta Barbara; Rimann Markus; Fussenegger Martin
Detailed design and comparative analysis of protocols for optimized production of high-performance HIV-1-derived lentiviral particles.
Metabolic engineering 2005;7(5-6):426-36.
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2005: Kelm Jens M; Diaz Sanchez-Bustamante Carlota; Ehler Elisabeth; Hoerstrup Simon P; Djonov Valentin; Ittner Lars; Fussenegger Martin
VEGF profiling and angiogenesis in human microtissues.
Journal of biotechnology 2005;118(2):213-29.
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2005: Kramer Beat P; Fischer Monika; Fussenegger Martin
Semi-synthetic mammalian gene regulatory networks.
Metabolic engineering 2005;7(4):241-50.
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2005: Kramer Beat P; Fussenegger Martin
Hysteresis in a synthetic mammalian gene network.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(27):9517-22.
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2005: Weber Wilfried; Spielmann Manuela; Daoud El-Baba Marie; Keller Bettina; Aubel Dominique; Fussenegger Martin
Tobacco smoke as inducer for gas phase-controlled transgene expression in mammalian cells and mice.
Biotechnology and bioengineering 2005;90(7):893-7.
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2005: Weber Cornelia C; Cai Hao; Ehrbar Martin; Kubota Hisashi; Martiny-Baron Georg; Weber Wilfried; Djonov Valentin; Weber Ernst; Mallik Ajit S; Fussenegger Martin; Frei Karl; Hubbell Jeffrey A; Zisch Andreas H
Effects of protein and gene transfer of the angiopoietin-1 fibrinogen-like receptor-binding domain on endothelial and vessel organization.
The Journal of biological chemistry 2005;280(23):22445-53.
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2005: Weber Wilfried; Rimann Markus; de Glutz François-Nicolas; Weber Eric; Memmert Klaus; Fussenegger Martin
Gas-inducible product gene expression in bioreactors.
Metabolic engineering 2005;7(3):174-81.
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2005: Weber Wilfried; Malphettes Laetitia; de Jesus Maria; Schoenmakers Ronald; El-Baba Marie Daoud; Spielmann Manuela; Keller Bettina; Weber Cornelia C; van de Wetering Petra; Aubel Dominique; Wurm Florian M; Fussenegger Martin
Engineered Streptomyces quorum-sensing components enable inducible siRNA-mediated translation control in mammalian cells and adjustable transcription control in mice.
The journal of gene medicine 2005;7(4):518-25.
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2005: Gonzalez-Nicolini Valeria; Fussenegger Martin
In vitro assays for anticancer drug discovery--a novel approach based on engineered mammalian cell lines.
Anti-cancer drugs 2005;16(3):223-8.
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2005: Weber Wilfried; Malphettes Laetitia; Rinderknecht Matthias; Schoenmakers Ronald G; Spielmann Manuela; Keller Bettina; van de Wetering Petra; Weber Cornelia C; Fussenegger Martin
Quorum-sensing-based toolbox for regulatable transgene and siRNA expression in mammalian cells.
Biotechnology progress 2005;21(1):178-85.
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2005: Franek Frantisek; Fussenegger Martin
Survival factor-like activity of small peptides in hybridoma and CHO cells cultures.
Biotechnology progress 2005;21(1):96-8.
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2005: Weber Cornelia C; Link Nils; Fux Cornelia; Zisch Andreas H; Weber Wilfried; Fussenegger Martin
Broad-spectrum protein biosensors for class-specific detection of antibiotics.
Biotechnology and bioengineering 2005;89(1):9-17.
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2005: Kramer Beat P; Fussenegger Martin
Transgene control engineering in mammalian cells.
Methods in molecular biology (Clifton, N.J.) 2005;308():123-43.
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2005: Malphettes Laetitia; Weber Cornelia C; El-Baba Marie Daoud; Schoenmakers Ronald G; Aubel Dominique; Weber Wilfried; Fussenegger Martin
A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1.
Nucleic acids research 2005;33(12):e107.
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2004: Weber Wilfried; Rinderknecht Matthias; Daoud-El Baba Marie; de Glutz François-Nicolas; Aubel Dominique; Fussenegger Martin
CellMAC: a novel technology for encapsulation of mammalian cells in cellulose sulfate/pDADMAC capsules assembled on a transient alginate/Ca2+ scaffold.
Journal of biotechnology 2004;114(3):315-26.
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2004: Weber Wilfried; Rimann Markus; Spielmann Manuela; Keller Bettina; Daoud-El Baba Marie; Aubel Dominique; Weber Cornelia C; Fussenegger Martin
Gas-inducible transgene expression in mammalian cells and mice.
Nature biotechnology 2004;22(11):1440-4.
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2004: Malphettes Laetitia; Fussenegger Martin
Macrolide- and tetracycline-adjustable siRNA-mediated gene silencing in mammalian cells using polymerase II-dependent promoter derivatives.
Biotechnology and bioengineering 2004;88(4):417-25.
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2004: Strasser H; Marksteiner R; Margreiter E; Pinggera G-M; Mitterberger M; Fritsch H; Klima G; Rädler C; Stadlbauer K-H; Fussenegger M; Hering S; Bartsch G
[Stem cell therapy for urinary incontinence]
Der Urologe. Ausg. A 2004;43(10):1237-41.
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2004: Weber Wilfried; Fussenegger Martin
Approaches for trigger-inducible viral transgene regulation in gene-based tissue engineering.
Current opinion in biotechnology 2004;15(5):383-91.
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2004: Fux Cornelia; Langer Dominik; Fussenegger Martin
Dual-regulated myoD- and msx1-based interventions in C2C12-derived cells enable precise myogenic/osteogenic/adipogenic lineage control.
The journal of gene medicine 2004;6(10):1159-69.
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2004: Kramer Beat P; Fischer Cornelius; Fussenegger Martin
BioLogic gates enable logical transcription control in mammalian cells.
Biotechnology and bioengineering 2004;87(4):478-84.
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2004: Gonzalez-Nicolini Valeria; Fux Cornelia; Fussenegger Martin
A novel mammalian cell-based approach for the discovery of anticancer drugs with reduced cytotoxicity on non-dividing cells.
Investigational new drugs 2004;22(3):253-62.
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2004: Chilov Dmitri; Fussenegger Martin
Toward construction of a self-sustained clock-like expression system based on the mammalian circadian clock.
Biotechnology and bioengineering 2004;87(2):234-42.
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2004: Kramer Beat P; Viretta Alessandro Usseglio; Daoud-El-Baba Marie; Aubel Dominique; Weber Wilfried; Fussenegger Martin
An engineered epigenetic transgene switch in mammalian cells.
Nature biotechnology 2004;22(7):867-70.
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2004: Viretta Alessandro Usseglio; Fussenegger Martin
Modeling the quorum sensing regulatory network of human-pathogenic Pseudomonas aeruginosa.
Biotechnology progress 2004;20(3):670-8.
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2004: Fux Cornelia; Langer Dominik; Kelm Jens M; Weber Wilfried; Fussenegger Martin
New-generation multicistronic expression platform: pTRIDENT vectors containing size-optimized IRES elements enable homing endonuclease-based cistron swapping into lentiviral expression vectors.
Biotechnology and bioengineering 2004;86(2):174-87.
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2004: Kelm Jens M; Fussenegger Martin
Microscale tissue engineering using gravity-enforced cell assembly.
Trends in biotechnology 2004;22(4):195-202.
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2004: Kelm Jens M; Kramer Beat P; Gonzalez-Nicolini Valeria; Ley Bettina; Fussenegger Martin
Synergies of microtissue design, viral transduction and adjustable transgene expression for regenerative medicine.
Biotechnology and applied biochemistry 2004;39(Pt 1):3-16.
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2004: Kelm Jens M; Ehler Elisabeth; Nielsen Lars K; Schlatter Stefan; Perriard Jean-Claude; Fussenegger Martin
Design of artificial myocardial microtissues.
Tissue engineering 2004;10(1-2):201-14.
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2004: Weber Wilfried; Fussenegger Martin
Inducible gene expression in mammalian cells and mice.
Methods in molecular biology (Clifton, N.J.) 2004;267():451-66.
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2004: Mitta Barbara; Weber Cornelia C; Rimann Markus; Fussenegger Martin
Design and in vivo characterization of self-inactivating human and non-human lentiviral expression vectors engineered for streptogramin-adjustable transgene expression.
Nucleic acids research 2004;32(12):e106.
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2004: Fux Cornelia; Mitta Barbara; Kramer Beat P; Fussenegger Martin
Dual-regulated expression of C/EBP-alpha and BMP-2 enables differential differentiation of C2C12 cells into adipocytes and osteoblasts.
Nucleic acids research 2004;32(1):e1.
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2003: Fux Cornelia; Weber Wilfried; Daoud-El Baba Marie; Heinzen Christoph; Aubel Dominique; Fussenegger Martin
Novel macrolide-adjustable bidirectional expression modules for coordinated expression of two different transgenes in mice.
The journal of gene medicine 2003;5(12):1067-79.
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2003: Fussenegger Martin; Meinhart Johann; Höbling Walter; Kullich Werner; Funk Siegfried; Bernatzky Günther
Stabilized autologous fibrin-chondrocyte constructs for cartilage repair in vivo.
Annals of plastic surgery 2003;51(5):493-8.
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2003: Chilov Dmitri; Fux Cornelia; Joch Hana; Fussenegger Martin
Identification of a novel proliferation-inducing determinant using lentiviral expression cloning.
Nucleic acids research 2003;31(18):e113.
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2003: Kramer Beat P; Weber Wilfried; Fussenegger Martin
Artificial regulatory networks and cascades for discrete multilevel transgene control in mammalian cells.
Biotechnology and bioengineering 2003;83(7):810-20.
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2003: Fux Cornelia; Fussenegger Martin
Bidirectional expression units enable streptogramin-adjustable gene expression in mammalian cells.
Biotechnology and bioengineering 2003;83(5):618-25.
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2003: Weber Wilfried; Schoenmakers Ronald; Spielmann Manuela; El-Baba Marie Daoud; Folcher Marc; Keller Bettina; Weber Cornelia C; Link Nils; van de Wetering Petra; Heinzen Christoph; Jolivet Benoît; Séquin Urs; Aubel Dominique; Thompson Charles J; Fussenegger Martin
Streptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice.
Nucleic acids research 2003;31(14):e71.
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2003: Schlatter Stefan; Senn Claudia; Fussenegger Martin
Modulation of translation-initiation in CHO-K1 cells by rapamycin-induced heterodimerization of engineered eIF4G fusion proteins.
Biotechnology and bioengineering 2003;83(2):210-25.
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2003: Kelm Jens M; Timmins Nicholas E; Brown Catherine J; Fussenegger Martin; Nielsen Lars K
Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types.
Biotechnology and bioengineering 2003;83(2):173-80.
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2003: Weber Wilfried; Marty René R; Link Nils; Ehrbar Martin; Keller Bettina; Weber Cornelia C; Zisch Andreas H; Heinzen Christoph; Djonov Valentin; Fussenegger Martin
Conditional human VEGF-mediated vascularization in chicken embryos using a novel temperature-inducible gene regulation (TIGR) system.
Nucleic acids research 2003;31(12):e69.
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2003: Fux Cornelia; Fussenegger Martin
Toward higher order control modalities in mammalian cells-independent adjustment of two different gene activities.
Biotechnology progress 2003;19(1):109-20.
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2003: Schlatter Stefan; Fussenegger Martin
Novel CNBP- and La-based translation control systems for mammalian cells.
Biotechnology and bioengineering 2003;81(1):1-12.
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2002: Meents Heiko; Enenkel Barbara; Eppenberger Hans M; Werner Rolf G; Fussenegger Martin
Impact of coexpression and coamplification of sICAM and antiapoptosis determinants bcl-2/bcl-x(L) on productivity, cell survival, and mitochondria number in CHO-DG44 grown in suspension and serum-free media.
Biotechnology and bioengineering 2002;80(6):706-16.
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2002: Weber Wilfried; Marty René R; Keller Bettina; Rimann Markus; Kramer Beat P; Fussenegger Martin
Versatile macrolide-responsive mammalian expression vectors for multiregulated multigene metabolic engineering.
Biotechnology and bioengineering 2002;80(6):691-705.
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2002: Weber Wilfried; Kramer Beat P; Fux Cornelia; Keller Bettina; Fussenegger Martin
Novel promoter/transactivator configurations for macrolide- and streptogramin-responsive transgene expression in mammalian cells.
The journal of gene medicine 2002;4(6):676-86.
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2002: Mitta Barbara; Rimann Markus; Ehrengruber Markus U; Ehrbar Martin; Djonov Valentin; Kelm Jens; Fussenegger Martin
Advanced modular self-inactivating lentiviral expression vectors for multigene interventions in mammalian cells and in vivo transduction.
Nucleic acids research 2002;30(21):e113.
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2002: Fussenegger Martin; Betenbaugh Michael J
Metabolic engineering II. Eukaryotic systems.
Biotechnology and bioengineering 2002;79(5):509-31.
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2002: Meents Heiko; Enenkel Barbara; Werner Rolf G; Fussenegger Martin
p27Kip1-mediated controlled proliferation technology increases constitutive sICAM production in CHO-DUKX adapted for growth in suspension and serum-free media.
Biotechnology and bioengineering 2002;79(6):619-27.
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2002: Weber Wilfried; Fux Cornelia; Daoud-el Baba Marie; Keller Bettina; Weber Cornelia C; Kramer Beat P; Heinzen Christoph; Aubel Dominique; Bailey James E; Fussenegger Martin
Macrolide-based transgene control in mammalian cells and mice.
Nature biotechnology 2002;20(9):901-7.
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2002: Weber Wilfried; Fussenegger Martin
Artificial mammalian gene regulation networks-novel approaches for gene therapy and bioengineering.
Journal of biotechnology 2002;98(2-3):161-87.
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2002: Schlatter Stefan; Rimann Markus; Kelm Jens; Fussenegger Martin
SAMY, a novel mammalian reporter gene derived from Bacillus stearothermophilus alpha-amylase.
Gene 2002;282(1-2):19-31.
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2001: Schlatter S; Bailey J E; Fussenegger M
Novel surface tagging technology for selection of complex proliferation-controlled mammalian cell phenotypes.
Biotechnology and bioengineering 2001;75(5):597-606.
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2001: Moser S; Rimann M; Fux C; Schlatter S; Bailey J E; Fussenegger M
Dual-regulated expression technology: a new era in the adjustment of heterologous gene expression in mammalian cells.
The journal of gene medicine 2001;3(6):529-49.
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2001: Kaufmann H; Marone R; Olayioye M A; Bailey J E; Fussenegger M
Characterization of an N-terminally truncated cyclin A isoform in mammalian cells.
The Journal of biological chemistry 2001;276(32):29987-93.
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2001: Frey A D; Rimann M; Bailey J E; Kallio P T; Thompson C J; Fussenegger M
Novel pristinamycin-responsive expression systems for plant cells.
Biotechnology and bioengineering 2001;74(2):154-63.
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2001: Kaufmann H; Mazur X; Marone R; Bailey J E; Fussenegger M
Comparative analysis of two controlled proliferation strategies regarding product quality, influence on tetracycline-regulated gene expression, and productivity.
Biotechnology and bioengineering 2001;72(6):592-602.
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2001: Fux C; Moser S; Schlatter S; Rimann M; Bailey J E; Fussenegger M
Streptogramin- and tetracycline-responsive dual regulated expression of p27(Kip1) sense and antisense enables positive and negative growth control of Chinese hamster ovary cells.
Nucleic acids research 2001;29(4):E19.
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2001: Aubel D; Morris R; Lennon B; Rimann M; Kaufmann H; Folcher M; Bailey J E; Thompson C J; Fussenegger M
Design of a novel mammalian screening system for the detection of bioavailable, non-cytotoxic streptogramin antibiotics.
The Journal of antibiotics 2001;54(1):44-55.
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2001: Fussenegger M
The impact of mammalian gene regulation concepts on functional genomic research, metabolic engineering, and advanced gene therapies.
Biotechnology progress 2001;17(1):1-51.
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2000: Fussenegger M; Morris R P; Fux C; Rimann M; von Stockar B; Thompson C J; Bailey J E
Streptogramin-based gene regulation systems for mammalian cells.
Nature biotechnology 2000;18(11):1203-8.
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2000: Moser S; Schlatter S; Fux C; Rimann M; Bailey J E; Fussenegger M
An update of pTRIDENT multicistronic expression vectors: pTRIDENTs containing novel streptogramin-responsive promoters.
Biotechnology progress 2000;16(5):724-35.
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2000: Fussenegger M; Bailey J E; Varner J
A mathematical model of caspase function in apoptosis.
Nature biotechnology 2000;18(7):768-74.
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2000: Zanghi J A; Renner W A; Bailey J E; Fussenegger M
The growth factor inhibitor suramin reduces apoptosis and cell aggregation in protein-free CHO cell batch cultures.
Biotechnology progress 2000;16(3):319-25.
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2000: Fussenegger M; Fassnacht D; Schwartz R; Zanghi J A; Graf M; Bailey J E; Pörtner R
Regulated overexpression of the survival factor bcl-2 in CHO cells increases viable cell density in batch culture and decreases DNA release in extended fixed-bed cultivation.
Cytotechnology 2000;32(1):45-61.
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1999: Mazur X; Eppenberger H M; Bailey J E; Fussenegger M
A novel autoregulated proliferation-controlled production process using recombinant CHO cells.
Biotechnology and bioengineering 1999;65(2):144-50.
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1999: Zanghi J A; Fussenegger M; Bailey J E
Serum protects protein-free competent Chinese hamster ovary cells against apoptosis induced by nutrient deprivation in batch culture.
Biotechnology and bioengineering 1999;64(1):108-19.
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1999: Kaufmann H; Mazur X; Fussenegger M; Bailey J E
Influence of low temperature on productivity, proteome and protein phosphorylation of CHO cells.
Biotechnology and bioengineering 1999;63(5):573-82.
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1999: Meinhart J; Fussenegger M; Höbling W
Stabilization of fibrin-chondrocyte constructs for cartilage reconstruction.
Annals of plastic surgery 1999;42(6):673-8.
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1998: Fussenegger M; Moser S; Bailey J E
pQuattro vectors allow one-step multigene metabolic engineering and auto-selection of quattrocistronic artificial mammalian operons.
Cytotechnology 1998;28(1-3):229-35.
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1998: Fussenegger M; Moser S; Bailey J E
Regulated multicistronic expression technology for mammalian metabolic engineering.
Cytotechnology 1998;28(1-3):111-26.
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1998: Fussenegger M; Bailey J E
Molecular regulation of cell-cycle progression and apoptosis in mammalian cells: implications for biotechnology.
Biotechnology progress 1998;14(6):807-33.
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1998: Steiner P; Fussenegger M; Bailey J E; Sauer U
Cloning and expression of the Zymomonas mobilis pyruvate kinase gene in Escherichia coli.
Gene 1998;220(1-2):31-8.
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1998: Mazur X; Fussenegger M; Renner W A; Bailey J E
Higher productivity of growth-arrested Chinese hamster ovary cells expressing the cyclin-dependent kinase inhibitor p27.
Biotechnology progress 1998;14(5):705-13.
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1998: Fussenegger M; Schlatter S; Dätwyler D; Mazur X; Bailey J E
Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells.
Nature biotechnology 1998;16(5):468-72.
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1998: Fussenegger M; Mazur X; Bailey J E
pTRIDENT, a novel vector family for tricistronic gene expression in mammalian cells.
Biotechnology and bioengineering 1998;57(1):1-10.
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1997: Fussenegger M; Moser S; Mazur X; Bailey J E
Autoregulated multicistronic expression vectors provide one-step cloning of regulated product gene expression in mammalian cells.
Biotechnology progress 1997;13(6):733-40.
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1997: Fussenegger M; Mazur X; Bailey J E
A novel cytostatic process enhances the productivity of Chinese hamster ovary cells.
Biotechnology and bioengineering 1997;55(6):927-39.
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