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Shiroh Futaki

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Chisato M Yamazaki; Yoshihiro Mashiyama; Ryo Masuda; Ikuhiko Nakase; Hiroyuki Endo; Shiroh Futaki; Saya Kishimoto; Takaki Koide
Collagen-like Cell-Penetrating Peptides.
Ikuhiko Nakase; Gen Tanaka; Shiroh Futaki
Cell-penetrating peptides (CPPs) as a vector for the delivery of siRNAs into cells.
Fatemeh Madani; Rania Abdo; Shiroh Futaki; Hisaaki Hirose; Ulo Langel; Staffan Lindberg; Astrid Gräslund
Modeling the endosomal escape of cell-penetrating peptides using a transmembrane pH gradient.

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2013: Chisato M Yamazaki; Yoshihiro Mashiyama; Ryo Masuda; Ikuhiko Nakase; Hiroyuki Endo; Shiroh Futaki; Saya Kishimoto; Takaki Koide
Collagen-like Cell-Penetrating Peptides.
Angewandte Chemie (International ed. in English) 2013;52(21):5497-500.
2013: Ikuhiko Nakase; Gen Tanaka; Shiroh Futaki
Cell-penetrating peptides (CPPs) as a vector for the delivery of siRNAs into cells.
Molecular bioSystems 2013;9(5):855-61.
2013: Fatemeh Madani; Rania Abdo; Shiroh Futaki; Hisaaki Hirose; Ulo Langel; Staffan Lindberg; Astrid Gräslund
Modeling the endosomal escape of cell-penetrating peptides using a transmembrane pH gradient.
Biochimica et biophysica acta 2013;1828(4):1198-204.
2013: Daisuke Noshiro; Kazuhiro Sonomura; Hao-Hsin Yu; Koji Asami; Miki Imanishi; Shiroh Futaki
Construction of a Ca(2+)-gated artificial channel by fusing alamethicin with a calmodulin-derived extramembrane segment.
Bioconjugate chemistry 2013;24(2):188-95.
2013: Yoshihiro Kuroda; Kazuhide Miyamoto; Eri Murata; Ikuhiko Nakase; Emi Tasaki; Yumi Tohyama; Koyo Ueda; Mineo Abe; Shiroh Futaki; Nahoko Kato-Kogoe; Munetaka Hirose
Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells.
European journal of pharmacology 2013;698(1-3):87-94.
2013: Shiroh Futaki; Hisaaki Hirose; Ikuhiko Nakase
Arginine-rich Peptides: Methods of Translocation Through Biological Membranes.
Current pharmaceutical design 2013;19(16):2863-8.
2012: Daisuke Noshiro; Koji Asami; Shiroh Futaki
Control of leakage activities of alamethicin analogs by metals: side chain-dependent adverse gating response to Zn(2+).
Bioorganic & medicinal chemistry 2012;20(23):6870-6.
2012: Yutaka Ueda; Fan-Yan Wei; Shiroh Futaki; Taku-ichiro Hide; Taku Kaitsuka; Jun-ichi Kuratsu; Keishi Makino; Hiroyuki Michiue; Hideo Nakamura; Kentaro Takayama; Kazuhito Tomizawa
Induction of autophagic cell death of glioma-initiating cells by cell-penetrating D-isomer peptides consisting of Pas and the p53 C-terminus.
Biomaterials 2012;33(35):9061-9.
2012: Gen Tanaka; Nobutaka Fujii; Yasunori Fukuda; Astrid Gräslund; Yasumaru Hatanaka; Yoshimasa Kawaguchi; Ulo Langel; Ryo Masuda; Masao Matsuoka; Ikuhiko Nakase; Shinya Oishi; Katsuya Okawa; Kazuya Shimura; Tomoka Takatani-Nakase; Shiroh Futaki
CXCR4 stimulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV.
Chemistry & biology 2012;19(11):1437-46.
2012: Ikuhiko Nakase; Shinya Okumura; Sílvia Pujals; Shigeomi Shimizu; Hirofumi Yamaguchi; Satoko Arakawa; Hisaaki Hirose; Sayaka Katayama; Shiroh Futaki
Transformation of an antimicrobial peptide into a plasma membrane-permeable, mitochondria-targeted peptide via the substitution of lysine with arginine.
Chemical communications (Cambridge, England) 2012;48(90):11097-9.
2012: Miki Imanishi; Hitoshi Okamura; Hiroyuki Yamada; Kazutoshi Yamamoto; Yuka Hirose; Shiroh Futaki
Construction of a rhythm transfer system that mimics the cellular clock.
ACS chemical biology 2012;7(11):1817-21.
2012: Yusuke Azuma; Haruka Imai; Miki Imanishi; Takeo Kawabata; Tomoyuki Yoshimura; Shiroh Futaki
Dipicolylamine as a unique structural switching element for helical peptides.
Organic & biomolecular chemistry 2012;10(30):6062-8.
2012: Ikuhiko Nakase; Shinya Okumura; Katsuhiro Osaki; Gen Tanaka; Miki Imanishi; Shiroh Futaki
Signal transduction using an artificial receptor system that undergoes dimerization upon addition of a bivalent leucine-zipper ligand.
Angewandte Chemie (International ed. in English) 2012;51(30):7464-7.
2012: Ikuhiko Nakase; Hidetaka Akita; Astrid Gräslund; Hideyoshi Harashima; Kentaro Kogure; Ulo Langel; Shiroh Futaki
Efficient intracellular delivery of nucleic acid pharmaceuticals using cell-penetrating peptides.
Accounts of chemical research 2012;45(7):1132-9.
2012: Kentaro Takayama; Gen Tanaka; Hisaaki Hirose; Sayaka Katayama; Ikuhiko Nakase; Sílvia Pujals; Shiroh Futaki
Effect of the attachment of a penetration accelerating sequence and the influence of hydrophobicity on octaarginine-mediated intracellular delivery.
Molecular pharmaceutics 2012;9(5):1222-30.
2012: Hisaaki Hirose; Sayaka Katayama; Shouhei Kobayashi; Ikuhiko Nakase; Hiroko Osakada; Sílvia Pujals; Toshihide Takeuchi; Tokuko Haraguchi; Shiroh Futaki
Transient focal membrane deformation induced by arginine-rich peptides leads to their direct penetration into cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(5):984-93.
2012: Ikuhiko Nakase; Hideo Saji; Masashi Ueda; Yusuke Konishi; Shiroh Futaki
Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery in vivo.
Journal of controlled release : official journal of the Controlled Release Society 2012;159(2):181-8.
2012: Miki Imanishi; Kazushi Matsumura; Tomohiro Nakaya; Shigeru Negi; Shiroh Futaki; Shogo Tsuji; Yukio Sugiura
Zn(II) binding and DNA binding properties of ligand-substituted CXHH-type zinc finger proteins.
Biochemistry 2012;51(16):3342-8.
2012: Hidetoshi Kono; Chie Nakayama; Shigeru Negi; Yui Sakaeda; Shiroh Futaki; Ayaka Hashimoto; Miki Imanishi; Kazuya Tatsutani; Yukio Sugiura
Rational design of DNA sequence-specific zinc fingers.
FEBS letters 2012;586(6):918-23.
2011: Miki Imanishi; Atsushi Nakamura; Masao Doi; Shiroh Futaki; Hitoshi Okamura
Control of circadian phase by an artificial zinc finger transcription regulator.
Angewandte Chemie (International ed. in English) 2011;50(40):9396-9.
2011: Sharif M Shaheen; Shota Takayama; Atsushi Yamashita; Nobuhiko Yui; Hidetaka Akita; Shiroh Futaki; Ryo Katoono; Takashi Nakamura; Hideyoshi Harashima
KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine.
Biomaterials 2011;32(26):6342-50.
2011: Yu Sakurai; Hiroto Hatakeyama; Yusuke Sato; Hidetaka Akita; Kentaro Takayama; Sachiko Kobayashi; Shiroh Futaki; Hideyoshi Harashima
Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA.
Biomaterials 2011;32(24):5733-42.
2011: Shigeru Negi; Maeko Sasaki; Shiroh Futaki; Miki Imanishi; Kazuya Tatsutani; Yukio Sugiura
An arginine residue instead of a conserved leucine residue in the recognition helix of the finger 3 of Zif268 stabilizes the domain structure and mediates DNA binding.
Biochemistry 2011;50(28):6266-72.
2011: Kazuhiro Sonomura; Hiroki Kuyama; Ei-ichi Matsuo; Susumu Tsunasawa; Shiroh Futaki; Osamu Nishimura
Selective isolation of N-blocked peptide by combining AspN digestion, transamination, and tosylhydrazine glass treatment.
Analytical biochemistry 2011;410(2):214-23.
2011: Shuhei Kawamoto; Masako Takasu; Takeshi Miyakawa; Ryota Morikawa; Tatsuki Oda; Shiroh Futaki; Hidemi Nagao
Inverted micelle formation of cell-penetrating peptide studied by coarse-grained simulation: importance of attractive force between cell-penetrating peptides and lipid head group.
The Journal of chemical physics 2011;134(9):095103.
2011: Hidetaka Akita; Kentaro Kogure; Rumiko Moriguchi; Yoshio Nakamura; Tomoko Higashi; Takashi Nakamura; Satoshi Serada; Minoru Fujimoto; Tetsuji Naka; Shiroh Futaki; Hideyoshi Harashima
Reprint of: Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation.
Journal of controlled release : official journal of the Controlled Release Society 2011;149(1):58-64.
2011: Sayaka Katayama; Hisaaki Hirose; Kentaro Takayama; Ikuhiko Nakase; Shiroh Futaki
Acylation of octaarginine: Implication to the use of intracellular delivery vectors.
Journal of controlled release : official journal of the Controlled Release Society 2011;149(1):29-35.
2011: Chung Yeng Looi; Yoji Sasahara; Miki Sato; Satoshi Takaki; Shigeru Tsuchiya; Natsuko Chiba; Shiroh Futaki; Miki Imanishi; Satoru Kumaki
Octa-arginine mediated delivery of wild-type Lnk protein inhibits TPO-induced M-MOK megakaryoblastic leukemic cell growth by promoting apoptosis.
PloS one 2011;6(8):e23640.
2011: Fatemeh Madani; Shiroh Futaki; Ulo Langel; Staffan Lindberg; Astrid Gräslund
Mechanisms of cellular uptake of cell-penetrating peptides.
Journal of biophysics (Hindawi Publishing Corporation : Online) 2011;2011():414729.
2011: Ikuhiko Nakase; Kentaro Kogure; Hideyoshi Harashima; Shiroh Futaki
Application of a fusiogenic peptide GALA for intracellular delivery.
Methods in molecular biology (Clifton, N.J.) 2011;683():525-33.
2010: Hao-Hsin Yu; Ikuhiko Nakase; Sílvia Pujals; Hisaaki Hirose; Gen Tanaka; Sayaka Katayama; Miki Imanishi; Shiroh Futaki
Expressed protein ligation for the preparation of fusion proteins with cell penetrating peptides for endotoxin removal and intracellular delivery.
Biochimica et biophysica acta 2010;1798(12):2249-57.
2010: Rei Miyamoto; Hiromichi Akizawa; Takeshi Nishikawa; Tomoya Uehara; Yusuke Azuma; Ikuhiko Nakase; Shiroh Futaki; Hirofumi Hanaoka; Yasuhiko Iida; Keigo Endo; Yasushi Arano
Enhanced target-specific accumulation of radiolabeled antibodies by conjugating arginine-rich peptides as anchoring molecules.
Bioconjugate chemistry 2010;21(11):2031-7.
2010: Miki Imanishi; Chika Imamura; Chika Higashi; Wei Yan; Shigeru Negi; Shiroh Futaki; Yukio Sugiura
Zinc finger-zinc finger interaction between the transcription factors, GATA-1 and Sp1.
Biochemical and biophysical research communications 2010;400(4):625-30.
2010: Kazuki Shimane; Eiichi N Kodama; Ikuhiko Nakase; Shiroh Futaki; Yasuteru Sakurai; Yasuko Sakagami; Xiaoguang Li; Toshio Hattori; Stefan G Sarafianos; Masao Matsuoka
Rev-derived peptides inhibit HIV-1 replication by antagonism of Rev and a co-receptor, CXCR4.
The international journal of biochemistry & cell biology 2010;42(9):1482-8.
2010: Miki Imanishi; Tomohiro Nakaya; Tatsuya Morisaki; Daisuke Noshiro; Shiroh Futaki; Yukio Sugiura
Metal-stimulated regulation of transcription by an artificial zinc-finger protein.
Chembiochem : a European journal of chemical biology 2010;11(12):1653-5.
2010: Daisuke Noshiro; Koji Asami; Shiroh Futaki
Metal-assisted channel stabilization: disposition of a single histidine on the N-terminus of alamethicin yields channels with extraordinarily long lifetimes.
Biophysical journal 2010;98(9):1801-8.
2010: Hidetaka Akita; Kentaro Kogure; Rumiko Moriguchi; Yoshio Nakamura; Tomoko Higashi; Takashi Nakamura; Satoshi Serada; Minoru Fujimoto; Tetsuji Naka; Shiroh Futaki; Hideyoshi Harashima
Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: programmed endosomal escape and dissociation.
Journal of controlled release : official journal of the Controlled Release Society 2010;143(3):311-7.
2010: Daiji Araki; Kentaro Takayama; Miyabi Inoue; Toyohiko Watanabe; Hiromi Kumon; Shiroh Futaki; Hideki Matsui; Kazuhito Tomizawa
Cell-penetrating D-isomer peptides of p53 C-terminus: long-term inhibitory effect on the growth of bladder cancer.
Urology 2010;75(4):813-9.
2010: Kazuhiro Shiga; Kentaro Takayama; Shiroh Futaki; Jessica E Hutti; Lewis C Cantley; Katsuko Ueki; Yoshitaka Ono; Hideyuki Mukai
Development of an intracellularly acting inhibitory peptide selective for PKN.
The Biochemical journal 2010;425(2):445-543.
2010: Hiroshi Yukawa; Hirofumi Noguchi; Ikuhiko Nakase; Yoshitaka Miyamoto; Koichi Oishi; Nobuyuki Hamajima; Shiroh Futaki; Shuji Hayashi
Transduction of cell-penetrating peptides into induced pluripotent stem cells.
Cell transplantation 2010;19(6):901-9.
2010: Ikuhiko Nakase; Sachiko Kobayashi; Shiroh Futaki
Endosome-disruptive peptides for improving cytosolic delivery of bioactive macromolecules.
Biopolymers 2010;94(6):763-70.
2010: Tatsuya Morisaki; Miki Imanishi; Shiroh Futaki; Yukio Sugiura
[Artificial transcription factors based on multi-zinc finger motifs].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010;130(1):45-8.
2009: Catherine L Watkins; Paul Brennan; Christopher Fegan; Kentaro Takayama; Ikuhiko Nakase; Shiroh Futaki; Arwyn T Jones
Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD.
Journal of controlled release : official journal of the Controlled Release Society 2009;140(3):237-44.
2009: Peter Guterstam; Fatemeh Madani; Hisaaki Hirose; Toshihide Takeuchi; Shiroh Futaki; Samir El-Andaloussi; Astrid Gräslund; Ulo Langel
Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate.
Biochimica et biophysica acta 2009;1788(12):2509-17.
2009: Ikuhiko Nakase; Shiroh Futaki
[Development of membrane-permeable peptide vectors and their internalization mechanisms].
Seikagaku. The Journal of Japanese Biochemical Society 2009;81(11):992-5.
2009: Ikuhiko Nakase; Hisaaki Hirose; Gen Tanaka; Akiko Tadokoro; Sachiko Kobayashi; Toshihide Takeuchi; Shiroh Futaki
Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(11):1868-76.
2009: Hiroto Hatakeyama; Erika Ito; Hidetaka Akita; Motoi Oishi; Yukio Nagasaki; Shiroh Futaki; Hideyoshi Harashima
A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo.
Journal of controlled release : official journal of the Controlled Release Society 2009;139(2):127-32.
2009: Miki Imanishi; Atsushi Nakamura; Tatsuya Morisaki; Shiroh Futaki
Positive and negative cooperativity of modularly assembled zinc fingers.
Biochemical and biophysical research communications 2009;387(3):440-3.
2009: Kentaro Takayama; Ikuhiko Nakase; Hiroyuki Michiue; Toshihide Takeuchi; Kazuhito Tomizawa; Hideki Matsui; Shiroh Futaki
Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas).
Journal of controlled release : official journal of the Controlled Release Society 2009;138(2):128-33.
2009: Dai Kurihara; Hidetaka Akita; Asako Kudo; Tomoya Masuda; Shiroh Futaki; Hideyoshi Harashima
Effect of polyethyleneglycol spacer on the binding properties of nuclear localization signal-modified liposomes to isolated nucleus.
Biological & pharmaceutical bulletin 2009;32(7):1303-6.
2009: Catherine L Watkins; Dirk Schmaljohann; Shiroh Futaki; Arwyn T Jones
Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide.
The Biochemical journal 2009;420(2):179-89.
2009: Sachiko Kobayashi; Ikuhiko Nakase; Noriko Kawabata; Hao-Hsin Yu; Sílvia Pujals; Miki Imanishi; Ernest Giralt; Shiroh Futaki
Cytosolic targeting of macromolecules using a pH-dependent fusogenic peptide in combination with cationic liposomes.
Bioconjugate chemistry 2009;20(5):953-9.
2009: Kohsuke Inomata; Ayako Ohno; Hidehito Tochio; Shin Isogai; Takeshi Tenno; Ikuhiko Nakase; Toshihide Takeuchi; Shiroh Futaki; Yutaka Ito; Hidekazu Hiroaki; Masahiro Shirakawa
High-resolution multi-dimensional NMR spectroscopy of proteins in human cells.
Nature 2009;458(7234):106-9.
2009: Ayman El-Sayed; Shiroh Futaki; Hideyoshi Harashima
Delivery of macromolecules using arginine-rich cell-penetrating peptides: ways to overcome endosomal entrapment.
The AAPS journal 2009;11(1):13-22.
2009: Ikuhiko Nakase; Byron Gallis; Tomoka Takatani-Nakase; Steve Oh; Eric Lacoste; Narendra P Singh; David R Goodlett; Seigo Tanaka; Shiroh Futaki; Henry Lai; Tomikazu Sasaki
Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis.
Cancer letters 2009;274(2):290-8.
2009: Kentaro Takayama; Akiko Tadokoro; Sílvia Pujals; Ikuhiko Nakase; Ernest Giralt; Shiroh Futaki
Novel system to achieve one-pot modification of cargo molecules with oligoarginine vectors for intracellular delivery.
Bioconjugate chemistry 2009;20(2):249-57.
2009: Akihiro Nishio; Nobuya Sawa; Keiko Onodera; Seiji Sakamoto; Yasuyuki Araki; Ikuhiko Nakase; Shiroh Futaki; Yoshihisa Inoue; Takehiko Wada
Studies on the effects of arginine residues introduced to peptide ribonucleic acids (PRNA) on the complex stability with RNA.
Nucleic acids symposium series (2004) 2009;(53):55-6.
2009: Yusuke Azuma; Miki Imanishi; Tomoyuki Yoshimura; Takeo Kawabata; Shiroh Futaki
Cobalt(II)-responsive DNA binding of a GCN4-bZIP protein containing cysteine residues functionalized with iminodiacetic acid.
Angewandte Chemie (International ed. in English) 2009;48(37):6853-6.
2008: Kentaro Takayama; Yuka Suehisa; Takuya Fujita; Jeffrey-Tri Nguyen; Shiroh Futaki; Akira Yamamoto; Yoshiaki Kiso; Yoshio Hayashi
Oligoarginine-based prodrugs with self-cleavable spacers for caco-2 cell permeation.
Chemical & pharmaceutical bulletin 2008;56(11):1515-20.
2008: Tatsuya Morisaki; Miki Imanishi; Shiroh Futaki; Yukio Sugiura
Rapid transcriptional activity in vivo and slow DNA binding in vitro by an artificial multi-zinc finger protein.
Biochemistry 2008;47(38):10171-7.
2008: Ayman El-Sayed; Ikramy A Khalil; Kentaro Kogure; Shiroh Futaki; Hideyoshi Harashima
Octaarginine- and octalysine-modified nanoparticles have different modes of endosomal escape.
The Journal of biological chemistry 2008;283(34):23450-61.
2008: Kentaro Sasaki; Kentaro Kogure; Shinji Chaki; Yoshio Nakamura; Rumiko Moriguchi; Hirofumi Hamada; Radostin Danev; Kuniaki Nagayama; Shiroh Futaki; Hideyoshi Harashima
An artificial virus-like nano carrier system: enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives.
Analytical and bioanalytical chemistry 2008;391(8):2717-27.
2008: Ikramy A Khalil; Kentaro Kogure; Shiroh Futaki; Hideyoshi Harashima
Octaarginine-modified liposomes: enhanced cellular uptake and controlled intracellular trafficking.
International journal of pharmaceutics 2008;354(1-2):39-48.
2008: Michie Kosuge; Toshihide Takeuchi; Ikuhiko Nakase; Arwyn T Jones; Shiroh Futaki
Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans.
Bioconjugate chemistry 2008;19(3):656-64.
2008: Shiroh Futaki
Membrane permeable peptide vectors: chemistry and functional design for the therapeutic applications.
Advanced drug delivery reviews 2008;60(4-5):447.
2008: Ikuhiko Nakase; Toshihide Takeuchi; Gen Tanaka; Shiroh Futaki
Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides.
Advanced drug delivery reviews 2008;60(4-5):598-607.
2008: Takehiko Wada; Nobuya Sawa; Hirofumi Sato; Shiroh Futaki; Yoshihisa Inoue
Effects of arginine residue introduction upon interaction and complexation behavior of peptide ribonucleic acids (PRNAs) with RNA: synthesis and properties of alpha-containing arginine.
Nucleic acids symposium series (2004) 2008;(52):673-4.
2007: Yoshio Hayashi; Kentaro Takayama; Yuka Suehisa; Takuya Fujita; Jeffrey-Tri Nguyen; Shiroh Futaki; Akira Yamamoto; Yoshiaki Kiso
Development of oligoarginine-drug conjugates linked to new peptidic self-cleavable spacers toward effective intestinal absorption.
Bioorganic & medicinal chemistry letters 2007;17(18):5129-32.
2007: Shiroh Futaki; Ikuhiko Nakase; Akiko Tadokoro; Toshihide Takeuchi; Arwyn T Jones
Arginine-rich peptides and their internalization mechanisms.
Biochemical Society transactions 2007;35(Pt 4):784-7.
2007: Wei Yan; Miki Imanishi; Shiroh Futaki; Yukio Sugiura
Alpha-helical linker of an artificial 6-zinc finger peptide contributes to selective DNA binding to a discontinuous recognition sequence.
Biochemistry 2007;46(29):8517-24.
2007: Atthachai Homhuan; Kentaro Kogure; Hideyuki Akaza; Shiroh Futaki; Takashi Naka; Yukiko Fujita; Ikuya Yano; Hideyoshi Harashima
New packaging method of mycobacterial cell wall using octaarginine-modified liposomes: enhanced uptake by and immunostimulatory activity of dendritic cells.
Journal of controlled release : official journal of the Controlled Release Society 2007;120(1-2):60-9.
2007: Yoshio Nakamura; Kentaro Kogure; Shiroh Futaki; Hideyoshi Harashima
Octaarginine-modified multifunctional envelope-type nano device for siRNA.
Journal of controlled release : official journal of the Controlled Release Society 2007;119(3):360-7.
2007: Shiroh Futaki; Koji Asami
Ligand-induced extramembrane conformation switch controlling alamethicin assembly and the channel current.
Chemistry & biodiversity 2007;4(6):1313-22.
2007: Marjan Fretz; Neal A Penning; Saly Al-Taei; Shiroh Futaki; Toshihide Takeuchi; Ikuhiko Nakase; Gert Storm; Arwyn T Jones
Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells.
The Biochemical journal 2007;403(2):335-42.
2007: Tomohiro Kimura; Keiko Ninomiya; Shiroh Futaki
NMR investigation of the electrostatic effect in binding of a neuropeptide, achatin-I, to phosphatidylcholine bilayers.
The journal of physical chemistry. B 2007;111(14):3831-8.
2007: I A Khalil; Kentaro Kogure; Shiroh Futaki; S Hama; H Akita; Masaharu Ueno; H Kishida; M Kudoh; Y Mishina; K Kataoka; M Yamada; Hideyoshi Harashima
Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery.
Gene therapy 2007;14(8):682-9.
2007: Ikuhiko Nakase; Akiko Tadokoro; Noriko Kawabata; Toshihide Takeuchi; Hironori Katoh; Kiyo Hiramoto; Manabu Negishi; Motoyoshi Nomizu; Yukio Sugiura; Shiroh Futaki
Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis.
Biochemistry 2007;46(2):492-501.
2007: Kaustabh K Maiti; Woo Sirl Lee; Toshihide Takeuchi; Catherine Watkins; Marjan Fretz; Dong-Chan Kim; Shiroh Futaki; Arwyn Jones; Kyong-Tai Kim; Sung-Kee Chung
Guanidine-containing molecular transporters: sorbitol-based transporters show high intracellular selectivity toward mitochondria.
Angewandte Chemie (International ed. in English) 2007;46(31):5880-4.
2007: Shouju Kameyama; Mayo Horie; Takeo Kikuchi; Takao Omura; Akiko Tadokoro; Toshihide Takeuchi; Ikuhiko Nakase; Yukio Sugiura; Shiroh Futaki
Acid wash in determining cellular uptake of Fab/cell-permeating peptide conjugates.
Biopolymers 2007;88(2):98-107.
2006: Marjan Fretz; Jing Jin; Robin Conibere; Neal A Penning; Saly Al-Taei; Gert Storm; Shiroh Futaki; Toshihide Takeuchi; Ikuhiko Nakase; Arwyn T Jones
Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):247-54.
2006: Toshihide Takeuchi; Michie Kosuge; Akiko Tadokoro; Yukio Sugiura; Mayumi Nishi; Mitsuhiro Kawata; Naomi Sakai; Stefan Matile; Shiroh Futaki
Direct and rapid cytosolic delivery using cell-penetrating peptides mediated by pyrenebutyrate.
ACS chemical biology 2006;1(5):299-303.
2006: Akitada Iwasa; Hidetaka Akita; Ikramy Khalil; Kentaro Kogure; Shiroh Futaki; Hideyoshi Harashima
Cellular uptake and subsequent intracellular trafficking of R8-liposomes introduced at low temperature.
Biochimica et biophysica acta 2006;1758(6):713-20.
2006: Takashi Nakamura; Rumiko Moriguchi; Kentaro Kogure; Arisa Minoura; Tomoya Masuda; Hidetaka Akita; Kazunori Kato; Hirofumi Hamada; Masaharu Ueno; Shiroh Futaki; Hideyoshi Harashima
Delivery of condensed DNA by liposomal non-viral gene delivery system into nucleus of dendritic cells.
Biological & pharmaceutical bulletin 2006;29(6):1290-3.
2006: Tatsuto Kiwada; Kazuhiro Sonomura; Yukio Sugiura; Koji Asami; Shiroh Futaki
Transmission of extramembrane conformational change into current: construction of metal-gated ion channel.
Journal of the American Chemical Society 2006;128(18):6010-1.
2006: Shouju Kameyama; Mayo Horie; Takeo Kikuchi; Takao Omura; Toshihide Takeuchi; Ikuhiko Nakase; Yukio Sugiura; Shiroh Futaki
Effects of cell-permeating peptide binding on the distribution of 125I-labeled Fab fragment in rats.
Bioconjugate chemistry 2006;17(3):597-602.
2006: Kaustabh K Maiti; Ock-Youm Jeon; Woo Sirl Lee; Dong-Chan Kim; Kyong-Tai Kim; Toshihide Takeuchi; Shiroh Futaki; Sung-Kee Chung
Design, synthesis, and membrane-translocation studies of inositol-based transporters.
Angewandte Chemie (International ed. in English) 2006;45(18):2907-12.
2006: Yoshio Nakamura; Kentaro Kogure; Yuma Yamada; Shiroh Futaki; Hideyoshi Harashima
Significant and prolonged antisense effect of a multifunctional envelope-type nano device encapsulating antisense oligodeoxynucleotide.
The Journal of pharmacy and pharmacology 2006;58(4):431-7.
2006: Shouju Kameyama; Ritsuko Okada; Takeo Kikuchi; Takao Omura; Ikuhiko Nakase; Toshihide Takeuchi; Yukio Sugiura; Shiroh Futaki
Distribution of immunoglobulin Fab fragment conjugated with HIV-1 REV peptide following intravenous administration in rats.
Molecular pharmaceutics 2006;3(2):174-80.
2006: Ikramy A Khalil; Kentaro Kogure; Shiroh Futaki; Hideyoshi Harashima
High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression.
The Journal of biological chemistry 2006;281(6):3544-51.
2006: Hidetaka Akita; Mitsuhide Tanimoto; Tomoya Masuda; Kentaro Kogure; Susumu Hama; Keiko Ninomiya; Shiroh Futaki; Hideyoshi Harashima
Evaluation of the nuclear delivery and intra-nuclear transcription of plasmid DNA condensed with micro (mu) and NLS-micro by cytoplasmic and nuclear microinjection: a comparative study with poly-L-lysine.
The journal of gene medicine 2006;8(2):198-206.
2006: Takehiko Wada; Yoshiki Maeda; Nobuya Sawa; Hirofumi Sato; Shiroh Futaki; Yoshihisa Inoue
RNA recognition and recognition control of alpha-peptide ribonucleic acids containing arginine residue by external factors.
Nucleic acids symposium series (2004) 2006;(50):75-6.
2006: Saly Al-Taei; Neal A Penning; Jeremy C Simpson; Shiroh Futaki; Toshihide Takeuchi; Ikuhiko Nakase; Arwyn T Jones
Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors.
Bioconjugate chemistry 2006;17(1):90-100.
2006: Shiroh Futaki
Oligoarginine vectors for intracellular delivery: design and cellular-uptake mechanisms.
Biopolymers 2006;84(3):241-9.
2005: Shiroh Futaki; Yumi Masui; Ikuhiko Nakase; Yukio Sugiura; Takashi Nakamura; Kentaro Kogure; Hideyoshi Harashima
Unique features of a pH-sensitive fusogenic peptide that improves the transfection efficiency of cationic liposomes.
The journal of gene medicine 2005;7(11):1450-8.
2005: Yuma Yamada; Yasuo Shinohara; Tomoyuki Kakudo; Shinji Chaki; Shiroh Futaki; Hiroyuki Kamiya; Hideyoshi Harashima
Mitochondrial delivery of mastoparan with transferrin liposomes equipped with a pH-sensitive fusogenic peptide for selective cancer therapy.
International journal of pharmaceutics 2005;303(1-2):1-7.
2005: Rumiko Moriguchi; Kentaro Kogure; Hidetaka Akita; Shiroh Futaki; Makoto Miyagishi; Kazunari Taira; Hideyoshi Harashima
A multifunctional envelope-type nano device for novel gene delivery of siRNA plasmids.
International journal of pharmaceutics 2005;301(1-2):277-85.
2005: Diky Mudhakir; Hidetaka Akita; Ikramy A Khalil; Shiroh Futaki; Hideyoshi Harashima
Pharmacokinetic analysis of the tissue distribution of octaarginine modified liposomes in mice.
Drug metabolism and pharmacokinetics 2005;20(4):275-81.
2005: Hirofumi Noguchi; Yusuke Nakai; Shinichi Matsumoto; Miho Kawaguchi; Michiko Ueda; Teru Okitsu; Yasuhiro Iwanaga; Yukihide Yonekawa; Hideo Nagata; Kohtaro Minami; Yumi Masui; Shiroh Futaki; Koichi Tanaka
Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(8):1848-55.
2005: Masamichi Nishihara; Florent PERRET; Toshihide Takeuchi; Shiroh Futaki; Adina N Lazar; Anthony W Coleman; Naomi Sakai; Stefan Matile
Arginine magic with new counterions up the sleeve.
Organic & biomolecular chemistry 2005;3(9):1659-69.
2005: Takako Nakatsukasa; Yasuhisa Shiraishi; Shigeru Negi; Miki Imanishi; Shiroh Futaki; Yukio Sugiura
Site-specific DNA cleavage by artificial zinc finger-type nuclease with cerium-binding peptide.
Biochemical and biophysical research communications 2005;330(1):247-52.
2005: Shiroh Futaki; Ikuhiko Nakase; Tomoki Suzuki; Daisuke Nameki; Eiichi Kodama; Masao Matsuoka; Yukio Sugiura
RNase S complex bearing arginine-rich peptide and anti-HIV activity.
Journal of molecular recognition : JMR 2005;18(2):169-74.
2005: Shiroh Futaki
Membrane-permeable arginine-rich peptides and the translocation mechanisms.
Advanced drug delivery reviews 2005;57(4):547-58.
2005: Florent PERRET; Masamichi Nishihara; Toshihide Takeuchi; Shiroh Futaki; Adina N Lazar; Anthony W Coleman; Naomi Sakai; Stefan Matile
Anionic fullerenes, calixarenes, coronenes, and pyrenes as activators of oligo/polyarginines in model membranes and live cells.
Journal of the American Chemical Society 2005;127(4):1114-5.
2005: Hirofumi Noguchi; Shinichi Matsumoto; Teru Okitsu; Yasuhiro Iwanaga; Yukihide Yonekawa; Hideo Nagata; Masayuki Matsushita; Fan-Yan Wei; Hideki Matsui; Kohtaro Minami; Susumu Seino; Yumi Masui; Shiroh Futaki; Koichi Tanaka
PDX-1 protein is internalized by lipid raft-dependent macropinocytosis.
Cell transplantation 2005;14(9):637-45.
2005: Naomi Sakai; Toshihide Takeuchi; Shiroh Futaki; Stefan Matile
Direct observation of anion-mediated translocation of fluorescent oligoarginine carriers into and across bulk liquid and anionic bilayer membranes.
Chembiochem : a European journal of chemical biology 2005;6(1):114-22.
2004: Shiroh Futaki; Tatsuto Kiwada; Yukio Sugiura
Control of peptide structure and recognition by Fe(III)-induced helix destabilization.
Journal of the American Chemical Society 2004;126(48):15762-9.
2004: Ikuhiko Nakase; Miki Niwa; Toshihide Takeuchi; Kazuhiro Sonomura; Noriko Kawabata; Yukihiro Koike; Masanori Takehashi; Seigo Tanaka; Kunihiro Ueda; Jeremy C Simpson; Arwyn T Jones; Yukio Sugiura; Shiroh Futaki
Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(6):1011-22.
2004: Kentaro Kogure; Rumiko Moriguchi; Kentaro Sasaki; Masaharu Ueno; Shiroh Futaki; Hideyoshi Harashima
Development of a non-viral multifunctional envelope-type nano device by a novel lipid film hydration method.
Journal of controlled release : official journal of the Controlled Release Society 2004;98(2):317-23.
2004: Tomoyuki Kakudo; Shinji Chaki; Shiroh Futaki; Ikuhiko Nakase; Kenichi Akaji; Toru Kawakami; Kazuo Maruyama; Hiroyuki Kamiya; Hideyoshi Harashima
Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system.
Biochemistry 2004;43(19):5618-28.
2004: Shiroh Futaki; Miki Niwa; Ikuhiko Nakase; Akiko Tadokoro; Youjun Zhang; Makoto Nagaoka; Naoya Wakako; Yukio Sugiura
Arginine carrier peptide bearing Ni(II) chelator to promote cellular uptake of histidine-tagged proteins.
Bioconjugate chemistry 2004;15(3):475-81.
2004: I A Khalil; Shiroh Futaki; M Niwa; Y Baba; N Kaji; H Kamiya; Hideyoshi Harashima
Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: enhanced cellular association by hydrophobic core formation.
Gene therapy 2004;11(7):636-44.
2004: Shiroh Futaki; Youjun Zhang; Tatsuto Kiwada; Ikuhiko Nakase; Takeshi Yagami; Shigetoshi Oiki; Yukio Sugiura
Gramicidin-based channel systems for the detection of protein-ligand interaction.
Bioorganic & medicinal chemistry 2004;12(6):1343-50.
2004: Tomohiko Ohwada; Daisuke Kojima; Tatsuto Kiwada; Shiroh Futaki; Yukio Sugiura; Kentaro Yamaguchi; Yoshinori Nishi; Yuji Kobayashi
Alpha,alpha-disubstituted glycines bearing a large hydrocarbon ring: peptide self-assembly through hydrophobic recognition.
Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(3):617-26.
2004: Shiroh Futaki; Kiwada Tatsuto; Yasuhisa Shiraishi; Yukio Sugiura
Total synthesis of artificial zinc-finger proteins: Problems and perspectives.
Biopolymers 2004;76(2):98-109.
2003: Akira Shibata; Syuichi Murata; Satoru Ueno; Shaoqian Liu; Shiroh Futaki; Yoshinobu Baba
Synthetic copoly(Lys/Phe) and poly(Lys) translocate through lipid bilayer membranes.
Biochimica et biophysica acta 2003;1616(2):147-55.
2003: Shiroh Futaki; Susumu Goto; Yukio Sugiura
Membrane permeability commonly shared among arginine-rich peptides.
Journal of molecular recognition : JMR 2003;16(5):260-4.
2003: Shiroh Futaki; Susumu Goto; Tomoki Suzuki; Ikuhiko Nakase; Yukio Sugiura
Structural variety of membrane permeable peptides.
Current protein & peptide science 2003;4(2):87-96.
2003: Takeshi Nagasaki; Teruhiko Myohoji; Taro Tachibana; Shiroh Futaki; Seizo Tamagaki
Can nuclear localization signals enhance nuclear localization of plasmid DNA?
Bioconjugate chemistry 2003;14(2):282-6.
2003: Rieko Tachibana; Shiroh Futaki; Hideyoshi Harashima; Hiroshi Kiwada
pH-sensitive liposomes in nuclear targeting of macromolecules.
Methods in enzymology 2003;372():349-61.
2002: Shiroh Futaki
Arginine-rich peptides: potential for intracellular delivery of macromolecules and the mystery of the translocation mechanisms.
International journal of pharmaceutics 2002;245(1-2):1-7.
2002: Shiroh Futaki
[Membrane permeable basic peptides: the potential of these peptides for the intracellular delivery of proteins and drugs].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2002;47(11):1415-9.
2002: Youjun Zhang; Shiroh Futaki; Tatsuto Kiwada; Yukio Sugiura
Detection of protein-ligand interaction on the membranes using C-terminus biotin-tagged alamethicin.
Bioorganic & medicinal chemistry 2002;10(8):2635-9.
2002: Seigo Tanaka; Masanori Takehashi; Naomi Matoh; Shinya Iida; Tomoki Suzuki; Shiroh Futaki; Hirofumi Hamada; Eliezer Masliah; Yukio Sugiura; Kunihiro Ueda
Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid.
Journal of neurochemistry 2002;82(2):305-15.
2002: Shiroh Futaki; Ikuhiko Nakase; Tomoki Suzuki; Zhang Youjun; Yukio Sugiura
Translocation of branched-chain arginine peptides through cell membranes: flexibility in the spatial disposition of positive charges in membrane-permeable peptides.
Biochemistry 2002;41(25):7925-30.
2002: Yuushi Okumura; Yuichi Kamikubo; Scott A Curriden; Jieyi Wang; Tatsuto Kiwada; Shiroh Futaki; Kouki Kitagawa; David J Loskutoff
Kinetic analysis of the interaction between vitronectin and the urokinase receptor.
The Journal of biological chemistry 2002;277(11):9395-404.
2002: Yoshiaki Yano; Tomokazu Takemoto; Satoe Kobayashi; Hiroyuki Yasui; Hiromu Sakurai; Wakana Ohashi; Miki Niwa; Shiroh Futaki; Yukio Sugiura; Katsumi Matsuzaki
Topological stability and self-association of a completely hydrophobic model transmembrane helix in lipid bilayers.
Biochemistry 2002;41(9):3073-80.
2002: Tomoki Suzuki; Shiroh Futaki; Miki Niwa; Seigo Tanaka; Kunihiro Ueda; Yukio Sugiura
Possible existence of common internalization mechanisms among arginine-rich peptides.
The Journal of biological chemistry 2002;277(4):2437-43.
2001: Shiroh Futaki; Masatora Fukuda; M Omote; K Yamauchi; T Yagami; M Niwa; Yukio Sugiura
Alamethicin-leucine zipper hybrid peptide: a prototype for the design of artificial receptors and ion channels.
Journal of the American Chemical Society 2001;123(49):12127-34.
2001: Shiroh Futaki; Wakana Ohashi; Tomoki Suzuki; Miki Niwa; Seigo Tanaka; Kunihiro Ueda; Hideyoshi Harashima; Yukio Sugiura
Stearylated arginine-rich peptides: a new class of transfection systems.
Bioconjugate chemistry 2001;12(6):1005-11.
2001: Shiroh Futaki; M Araki; Tatsuto Kiwada; Ikuhiko Nakase; Yukio Sugiura
A 'cassette' RNase: site-selective cleavage of RNA by RNase S equipped with RNA-recognition segment.
Bioorganic & medicinal chemistry letters 2001;11(9):1165-8.
2001: Masaya Takikawa; Masaharu Kamada; Masahiko Maegawa; Shuji Yamano; Minoru Irahara; Toshihiro Aono; Shiroh Futaki; Yasukazu Ohmoto; Samuel S Koide
Evaluation of two sperm antigens, rSMP-B and YWK-II, as targets for immunocontraception.
Zygote (Cambridge, England) 2001;9(2):145-51.
2001: Naokatu Arakaki; Y Ueyama; M Hirose; Toshiki Himeda; Hirofumi Shibata; Shiroh Futaki; K Kitagawa; Tomihiko Higuti
Stoichiometry of subunit e in rat liver mitochondrial H(+)-ATP synthase and membrane topology of its putative Ca(2+)-dependent regulatory region.
Biochimica et biophysica acta 2001;1504(2-3):220-8.
2001: Masaharu Kamada; Masaya Takikawa; Masahiko Maegawa; Satoshi Yamamoto; Shuji Yamano; Minoru Irahara; Toshihiro Aono; Shiroh Futaki; Yasukazu Ohmoto; S Koide
Specific cytotoxicity of antibody to YAL-198, a sperm antigen peptide, to murine zygote.
Archives of andrology 2001;47(2):89-96.
2001: Shiroh Futaki; Tomoki Suzuki; Wakana Ohashi; T Yagami; Seigo Tanaka; Kunihiro Ueda; Yukio Sugiura
Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery.
The Journal of biological chemistry 2001;276(8):5836-40.
2000: Yuichiro Hori; K Suzuki; Yasushi Okuno; Makoto Nagaoka; Shiroh Futaki; Yukio Sugiura
The engineering, structure, and DNA binding properties of a novel His4-type zinc finger peptide.
Nucleic acids symposium series 2000;(44):295-6.
1999: Masaharu Kamada; Satoshi Yamamoto; Masaya Takikawa; Kotaro Kunimi; Masahiko Maegawa; Shiroh Futaki; Yasukazu Ohmoto; Toshihiro Aono; Samuel S Koide
Identification of the human sperm protein that interacts with sperm-immobilizing antibodies in the sera of infertile women.
Fertility and sterility 1999;72(4):691-5.
1999: Shiroh Futaki; M Aoki; T Ishikawa; F Kondo; T Asahara; M Niwa; Y Nakaya; T Yagami; K Kitagawa
Chemical ligation to obtain proteins comprising helices with individual amino acid sequences.
Bioorganic & medicinal chemistry 1999;7(1):187-92.
1998: Rieko Tachibana; Hideyoshi Harashima; Masayuki Shono; M Azumano; M Niwa; Shiroh Futaki; Hiroshi Kiwada
Intracellular regulation of macromolecules using pH-sensitive liposomes and nuclear localization signal: qualitative and quantitative evaluation of intracellular trafficking.
Biochemical and biophysical research communications 1998;251(2):538-44.
1998: Masaharu Kamada; H Mori; N Maeda; Satoshi Yamamoto; Kotaro Kunimi; Masaya Takikawa; Masahiko Maegawa; Toshihiro Aono; Shiroh Futaki; Samuel S Koide
beta-Microseminoprotein/prostatic secretory protein is a member of immunoglobulin binding factor family.
Biochimica et biophysica acta 1998;1388(1):101-10.
1998: H Mori; Masaharu Kamada; Masahiko Maegawa; Satoshi Yamamoto; Toshihiro Aono; Shiroh Futaki; Makiko Yano; Hiroshi Kido; Samuel S Koide
Enzymatic activation of immunoglobulin binding factor in female reproductive tract.
Biochemical and biophysical research communications 1998;246(2):409-13.
1998: Y Tsutsumishita; T Onda; K Okada; M Takeda; H Endou; Shiroh Futaki; M Niwa
Involvement of H2O2 production in cisplatin-induced nephrotoxicity.
Biochemical and biophysical research communications 1998;242(2):310-2.
1998: Shiroh Futaki
Peptide ion channels: design and creation of function.
Biopolymers 1998;47(1):75-81.
1997: M Niwa; N Nakamura; K Kitajima; M Ueda; Y Tsutsumishita; Shiroh Futaki; Y Takaishi
Benzoquinones inhibit the expression of inducible nitric oxide synthase gene.
Biochemical and biophysical research communications 1997;239(2):367-71.
1997: Shiroh Futaki; T Ishikawa; M Niwa; K Kitagawa; T Yagami
Embodying a stable alpha-helical protein structure through efficient chemical ligation via thioether formation.
Bioorganic & medicinal chemistry 1997;5(9):1883-91.
1996: Y Tsutsumishita; Y Kawai; H Takahara; T Onda; J Miyoshi; Shiroh Futaki; M Niwa
Sequence analysis of inducible nitric oxide synthase in rat kidney, lung, and uterus.
Biological & pharmaceutical bulletin 1996;19(10):1374-6.
1996: M Niwa; Y Tsutsumishita; Y Kawai; H Takahara; N Nakamura; Shiroh Futaki; Yoshihisa Takaishi; W Kondoh; H Moritoki
Suppression of inducible nitric oxide synthase mRNA expression by tryptoquinone A.
Biochemical and biophysical research communications 1996;224(2):579-85.
1994: Masaharu Kamada; N Maeda; Masahiko Maegawa; H Mori; S Yamamoto; Toshihiro Aono; M Muraguchi; Yasukazu Ohmoto; Shiroh Futaki; Fumitaka Ogushi
Detection of immunoglobulin binding factor by enzyme-linked immunosorbent assay using two monoclonal antibodies.
Biochemistry and molecular biology international 1994;34(4):837-44.
1994: K Kitagawa; Shiroh Futaki; T Yagami; S Sumi; K Inoue
Solid-phase synthesis of cionin, a protochordate-derived octapeptide related to the gastrin/cholecystokinin family of peptides, and its mono-tyrosine-sulfate-containing derivatives.
International journal of peptide and protein research 1994;43(2):190-200.
1994: N Maeda; Masaharu Kamada; T Daitoh; Masahiko Maegawa; K Hirano; Toshihiro Aono; T Shiotsu; H Kanayama; S Kagawa; Shiroh Futaki
Immunoglobulin binding factor: a new tumor marker for prostatic tumors.
The Prostate 1994;24(3):125-30.
1993: N Maeda; Masaharu Kamada; T Daitoh; Toshihiro Aono; Shiroh Futaki; Z G Liang; Samuel S Koide
Immunoglobulin binding factor in human seminal plasma: immunological function.
Archives of andrology 1993;31(1):31-6.
1993: T Yagami; S Shiwa; Shiroh Futaki; K Kitagawa
Evaluation of the final deprotection system for the solid-phase synthesis of Tyr(SO3H)-containing peptides with 9-fluorenylmethyloxycarbonyl (Fmoc)-strategy and its application to the synthesis of cholecystokinin (CCK)-12.
Chemical & pharmaceutical bulletin 1993;41(2):376-80.
1990: K Kitagawa; T Tomoyasu; Shiroh Futaki; T Akita; S Higashide; K Inoue; T Tobe
Solution synthesis of human peptide YY (hPYY).
Chemical & pharmaceutical bulletin 1990;38(6):1731-4.
1989: T Oda; Shiroh Futaki; K Kitagawa; Y Yoshihara; I Tani; Tomihiko Higuti
Orientation of chargerin II (A6L) in the ATP synthase of rat liver mitochondria determined with antibodies against peptides of the protein.
Biochemical and biophysical research communications 1989;165(1):449-56.
1989: S Ono; S Kiyama; K Kitagawa; Shiroh Futaki; T Nakamura; T Taike; T Akita; S Sumi; K Inoue; M Fujimura
Application of the trimethylsilyl trifluoromethanesulfonate deprotecting procedure for the synthesis of porcine peptide YY (PYY).
International journal of peptide and protein research 1989;33(1):29-38.