FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Bernard Futscher

Research Profile

Anatomy

Physiology

Chemicals & Drugs

Procedures

Genes & Molecular Sequences

Genes, Tumor Suppressor

Co-author Network

Publications

TOP 3
Brandon T Nokes; Robert B Livingston; David W Mount; Heather E Cunliffe; Bernard W Futscher; Bonnie Lafleur; Julie Lang
In Vitro Assessment of the Inflammatory Breast Cancer Cell Line SUM 149: Discovery of 2 Single Nucleotide Polymorphisms in the RNase L Gene.
Lukas Vrba; José L Muñoz-Rodríguez; Martha R Stampfer; Bernard W Futscher
miRNA gene promoters are frequent targets of aberrant DNA methylation in human breast cancer.
Bernard W Futscher
Epigenetic changes during cell transformation.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Bernard Futscher (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Brandon T Nokes; Robert B Livingston; David W Mount; Heather E Cunliffe; Bernard W Futscher; Bonnie Lafleur; Julie Lang
In Vitro Assessment of the Inflammatory Breast Cancer Cell Line SUM 149: Discovery of 2 Single Nucleotide Polymorphisms in the RNase L Gene.
Journal of Cancer 2013;4(2):104-16.
2013: Lukas Vrba; José L Muñoz-Rodríguez; Martha R Stampfer; Bernard W Futscher
miRNA gene promoters are frequent targets of aberrant DNA methylation in human breast cancer.
PloS one 2013;8(1):e54398.
2013: Bernard W Futscher
Epigenetic changes during cell transformation.
Advances in experimental medicine and biology 2013;754():179-94.
2012: Paul L Severson; Erik J Tokar; Lukas Vrba; Michael P Waalkes; Bernard W Futscher
Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation.
Epigenetics : official journal of the DNA Methylation Society 2012;7(11):1238-48.
2012: Petr Novak; Martha R Stampfer; Jose L Munoz-Rodriguez; Mathias Ehrich; Bernard W Futscher; James C Garbe; Taylor J Jensen
Cell-type specific DNA methylation patterns define human breast cellular identity.
PloS one 2012;7(12):e52299.
2012: Melissa L T Teoh-Fitzgerald; Matthew P Fitzgerald; Bernard W Futscher; Taylor J Jensen; Frederick E Domann
Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis.
Molecular cancer research : MCR 2012;10(1):40-51.
2011: Lukas Vrba; James C Garbe; Martha R Stampfer; Bernard W Futscher
Epigenetic regulation of normal human mammary cell type-specific miRNAs.
Genome research 2011;21(12):2026-37.
2011: Vijayababu M Radhakrishnan; Haiyan Cui; Bernard W Futscher; Taylor J Jensen; Jesse D Martinez
Hypomethylation of the 14-3-3σ promoter leads to increased expression in non-small cell lung cancer.
Genes, chromosomes & cancer 2011;50(10):830-6.
2011: J Christopher States; John F Reichard; Aaron Barchowsky; Iain L Cartwright; Bernard W Futscher; R Clark Lantz
Arsenic toxicology: translating between experimental models and human pathology.
Environmental health perspectives 2011;119(10):1356-63.
2010: Shawn M Wnek; Taylor J Jensen; Paul L Severson; Bernard W Futscher; A Jay Gandolfi
Monomethylarsonous acid produces irreversible events resulting in malignant transformation of a human bladder cell line following 12 weeks of low-level exposure.
Toxicological sciences : an official journal of the Society of Toxicology 2010;116(1):44-57.
2010: Lukas Vrba; Taylor J Jensen; James C Garbe; Ronald L Heimark; Anne E Cress; Sally Dickinson; Martha R Stampfer; Bernard W Futscher
Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells.
PloS one 2010;5(1):e8697.
2009: Taylor J Jensen; Petr Novak; Shawn M Wnek; A Jay Gandolfi; Bernard W Futscher
Arsenicals produce stable progressive changes in DNA methylation patterns that are linked to malignant transformation of immortalized urothelial cells.
Toxicology and applied pharmacology 2009;241(2):221-9.
2009: Novak Petr; Taylor J Jensen; James C Garbe; Martha R Stampfer; Bernard W Futscher
Stepwise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization.
Cancer research 2009;69(12):5251-8.
2009: Taylor J Jensen; Ryan Wozniak; Kylee E Eblin; Sean M Wnek; A Jay Gandolfi; Bernard W Futscher
Epigenetic mediated transcriptional activation of WNT5A participates in arsenical-associated malignant transformation.
Toxicology and applied pharmacology 2009;235(1):39-46.
2009: K E Eblin; T J Jensen; S M Wnek; S E Buffington; Bernard W Futscher; A J Gandolfi
Reactive oxygen species regulate properties of transformation in UROtsa cells exposed to monomethylarsonous acid by modulating MAPK signaling.
Toxicology 2009;255(1-2):107-14.
2008: Novak Petr; Taylor Jensen; Marc M Oshiro; George S Watts; Christina J Kim; Bernard W Futscher
Agglomerative epigenetic aberrations are a common event in human breast cancer.
Cancer research 2008;68(20):8616-25.
2008: Kylee E Eblin; A M Hau; T J Jensen; Bernard W Futscher; A Gandolfi
The role of reactive oxygen species in arsenite and monomethylarsonous acid-induced signal transduction in human bladder cells: acute studies.
Toxicology 2008;250(1):47-54.
2008: Taylor J Jensen; Novak Petr; Kylee E Eblin; A Gandolfi; Bernard W Futscher
Epigenetic remodeling during arsenical-induced malignant transformation.
Carcinogenesis 2008;29(8):1500-8.
2008: Damian J Junk; Lukas Vrba; George S Watts; Marc M Oshiro; Jesse D Martinez; Bernard W Futscher
Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells.
Neoplasia (New York, N.Y.) 2008;10(5):450-61.
2008: Lukas Vrba; Damian J Junk; Novak Petr; Bernard W Futscher
p53 induces distinct epigenetic states at its direct target promoters.
BMC genomics 2008;9():486.
2008: George S Watts; Bernard W Futscher; Nicholas Holtan; Koen DeGeest; Frederick E Domann; Stephen L Rose
DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage.
BMC medical genomics 2008;1():47.
2007: Jiexun Li; Hua Su; Hsinchun Chen; Bernard W Futscher
Optimal search-based gene subset selection for gene array cancer classification.
IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society 2007;11(4):398-405.
2007: Adriana Beltran Lopez; S Parikh; Yuangang Liu; Bruce D Cuevas; Gary L Johnson; Bernard W Futscher; Pilar Blancafort
Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors.
Oncogene 2007;26(19):2791-8.
2007: Ryan Wozniak; Walter T Klimecki; Serrine S Lau; Y Feinstein; Bernard W Futscher
5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation.
Oncogene 2007;26(1):77-90.
2006: Natalia A Ignatenko; Hagit F Yerushalmi; George S Watts; Bernard W Futscher; David E Stringer; Laurence J Marton; Eugene W Gerner
Pharmacogenomics of the polyamine analog 3,8,13,18-tetraaza-10,11-[(E)-1,2-cyclopropyl]eicosane tetrahydrochloride, CGC-11093, in the colon adenocarcinoma cell line HCT1161.
Technology in cancer research & treatment 2006;5(6):553-64.
2006: Novak Petr; Taylor Jensen; Marc M Oshiro; Ryan Wozniak; Marcella Nouzova; George S Watts; Walter T Klimecki; Christina Kim; Bernard W Futscher
Epigenetic inactivation of the HOXA gene cluster in breast cancer.
Cancer research 2006;66(22):10664-70.
2006: H Li; George S Watts; Marc M Oshiro; Bernard W Futscher; Frederick E Domann
AP-2alpha and AP-2gamma are transcriptional targets of p53 in human breast carcinoma cells.
Oncogene 2006;25(39):5405-15.
2006: Stephen L Rose; Matthew P Fitzgerald; Natalie O White; Michael J Hitchler; Bernard W Futscher; Koen De Geest; Frederick E Domann
Epigenetic regulation of maspin expression in human ovarian carcinoma cells.
Gynecologic oncology 2006;102(2):319-24.
2006: Brian L Pike; Susan Groshen; Ya-Hsuan Hsu; Ruty Mehrian Shai; Xiaoming Wang; Nicholas Holtan; Bernard W Futscher; Joseph G Hacia
Comparisons of PCR-based genome amplification systems using CpG island microarrays.
Human mutation 2006;27(6):589-96.
2005: Marc M Oshiro; Bernard W Futscher; Aaron Lisberg; Ryan Wozniak; Walter T Klimecki; Frederick E Domann; Anne E Cress
Epigenetic regulation of the cell type-specific gene 14-3-3sigma.
Neoplasia (New York, N.Y.) 2005;7(9):799-808.
2005: Marc M Oshiro; Christina J Kim; Ryan Wozniak; Damian J Junk; José L Muñoz-Rodríguez; Jeanne A Burr; Matthew Fitzgerald; Sangita C Pawar; Anne E Cress; Frederick E Domann; Bernard W Futscher
Epigenetic silencing of DSC3 is a common event in human breast cancer.
Breast cancer research : BCR 2005;7(5):R669-80.
2004: M Nouzova; Nicholas Holtan; Marc M Oshiro; RB Isett; J L Munoz-Rodriguez; Alan F List; M L Narro; S J Miller; N C Merchant; Bernard W Futscher
Epigenomic changes during leukemia cell differentiation: analysis of histone acetylation and cytosine methylation using CpG island microarrays.
The Journal of pharmacology and experimental therapeutics 2004;311(3):968-81.
2004: Bernard W Futscher; Megan M O'Meara; Christina J Kim; Margaret A Rennels; Di Lu; Lynn M Gruman; Richard E B Seftor; Mary J C Hendrix; Frederick E Domann
Aberrant methylation of the maspin promoter is an early event in human breast cancer.
Neoplasia (New York, N.Y.) 2004;6(4):380-9.
2004: Frederick E Domann; Bernard W Futscher
Flipping the epigenetic switch.
The American journal of pathology 2004;164(6):1883-6.
2004: George S Watts; Marc M Oshiro; Damian J Junk; Ryan Wozniak; Summer Watterson; Frederick E Domann; Bernard W Futscher
The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells.
Neoplasia (New York, N.Y.) 2004;6(3):187-94.
2003: Hong Duan; Hannah J Zhang; Ji-Qin Yang; Larry W Oberley; Bernard W Futscher; Frederick E Domann
MnSOD up-regulates maspin tumor suppressor gene expression in human breast and prostate cancer cells.
Antioxidants & redox signaling 2003;5(5):677-88.
2003: Matthew Fitzgerald; Marc M Oshiro; Nicholas Holtan; Kimberly Krager; Joseph J Cullen; Bernard W Futscher; Frederick E Domann
Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control.
Neoplasia (New York, N.Y.) 2003;5(5):427-36.
2003: Marc M Oshiro; George S Watts; Ryan Wozniak; Damian J Junk; Jose L Munoz-Rodriguez; Frederick E Domann; Bernard W Futscher
Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression.
Oncogene 2003;22(23):3624-34.
2003: Frederick E Domann; Bernard W Futscher
Editorial: maspin as a molecular target for cancer therapy.
The Journal of urology 2003;169(3):1162-4.
2002: Cara L Crowley-Weber; Claire M Payne; Mary Gleason-Guzman; George S Watts; Bernard W Futscher; Caroline N Waltmire; Cheray Crowley; Katerina Dvorakova; Carol Bernstein; Mary Craven; Harinder Garewal; Harris Bernstein
Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Carcinogenesis 2002;23(12):2063-80.
2002: Bernard W Futscher; Marc M Oshiro; Ryan Wozniak; Nicholas Holtan; Christin L Hanigan; Hong Duan; Frederick E Domann
Role for DNA methylation in the control of cell type specific maspin expression.
Nature genetics 2002;31(2):175-9.
2001: George S Watts; Bernard W Futscher; RB Isett; Mary Gleason-Guzman; M W Kunkel; Sydney E Salmon
cDNA microarray analysis of multidrug resistance: doxorubicin selection produces multiple defects in apoptosis signaling pathways.
The Journal of pharmacology and experimental therapeutics 2001;299(2):434-41.
2001: Tracy L Davis; I Rabinovitz; Bernard W Futscher; M Schnölzer; F Burger; Yuangang Liu; Molly Kulesz-Martin; Anne E Cress
Identification of a novel structural variant of the alpha 6 integrin.
The Journal of biological chemistry 2001;276(28):26099-106.
2001: Thomas Efferth; Bernard W Futscher; Rainhardt Osieka
5-Azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs.
Blood cells, molecules & diseases 2001;27(3):637-48.
2001: Robert Calaluce; M W Kunkel; George S Watts; Monika Schmelz; Junshan Hao; Jean Barrera; Mary Gleason-Guzman; RB Isett; M Fitchmun; George Bowden; Anne E Cress; Bernard W Futscher; Raymond B Nagle
Laminin-5-mediated gene expression in human prostate carcinoma cells.
Molecular carcinogenesis 2001;30(2):119-29.
2000: JC Rice; Hilmi Ozcelik; P Maxeiner; I Andrulis; Bernard W Futscher
Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens.
Carcinogenesis 2000;21(9):1761-5.
2000: JC Rice; Bernard W Futscher
Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter.
Nucleic acids research 2000;28(17):3233-9.
2000: Frederick E Domann; JC Rice; Mary J C Hendrix; Bernard W Futscher
Epigenetic silencing of maspin gene expression in human breast cancers.
International journal of cancer. Journal international du cancer 2000;85(6):805-10.
1999: M K Mitchell; Bernard W Futscher; Charlene A McQueen
Developmental expression of N-acetyltransferases in C57BI/6 mice.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(2):261-4.
1998: J E Dodge; Alan F List; Bernard W Futscher
Selective variegated methylation of the p15 CpG island in acute myeloid leukemia.
International journal of cancer. Journal international du cancer 1998;78(5):561-7.
1998: JC Rice; KS Massey-Brown; Bernard W Futscher
Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells.
Oncogene 1998;17(14):1807-12.
1997: George S Watts; R O Pieper; Joseph F Costello; Yei-Mei Peng; W S Dalton; Bernard W Futscher
Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene.
Molecular and cellular biology 1997;17(9):5612-9.
1997: H Wang; Z g Jiang; YW Wong; W S Dalton; Bernard W Futscher; V T Chan
Decreased CP-1 (NF-Y) activity results in transcriptional down-regulation of topoisomerase IIalpha in a doxorubicin-resistant variant of human multiple myeloma RPMI 8226.
Biochemical and biophysical research communications 1997;237(2):217-24.
1996: M R Abbaszadegan; A E Cress; Bernard W Futscher; William T Bellamy; William S Dalton
Evidence for cytoplasmic P-glycoprotein location associated with increased multidrug resistance and resistance to chemosensitizers.
Cancer research 1996;56(23):5435-42.
1996: R O Pieper; S Patel; S A Ting; Bernard W Futscher; Joseph F Costello
Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene.
The Journal of biological chemistry 1996;271(23):13916-24.
1996: Bernard W Futscher; N E Foley; Mary Gleason-Guzman; P S Meltzer; D M Sullivan; William S Dalton
Verapamil suppresses the emergence of P-glycoprotein-mediated multi-drug resistance.
International journal of cancer. Journal international du cancer 1996;66(4):520-5.
1995: G S Watts; Bernard W Futscher
Detecting differences in 5-methylcytosine using restriction enzyme isoschizomers: an endogenous control for complete digestion.
Nucleic acids research 1995;23(22):4740-1.
1994: Joseph F Costello; Bernard W Futscher; Roger Kroes; R O Pieper
Methylation-related chromatin structure is associated with exclusion of transcription factors from and suppressed expression of the O-6-methylguanine DNA methyltransferase gene in human glioma cell lines.
Molecular and cellular biology 1994;14(10):6515-21.
1994: M R Abbaszadegan; Bernard W Futscher; W T Klimecki; A List; William S Dalton
Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells.
Cancer research 1994;54(17):4676-9.
1994: Joseph F Costello; Bernard W Futscher; K Tano; D M Graunke; R O Pieper
Graded methylation in the promoter and body of the O6-methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells.
The Journal of biological chemistry 1994;269(25):17228-37.
1994: W T Klimecki; Bernard W Futscher; William S Dalton
Effects of ethanol and paraformaldehyde on RNA yield and quality.
BioTechniques 1994;16(6):1021-3.
1994: W T Klimecki; Bernard W Futscher; Thomas M Grogan; William S Dalton
P-glycoprotein expression and function in circulating blood cells from normal volunteers.
Blood 1994;83(9):2451-8.
1994: Bernard W Futscher; M R Abbaszadegan; F Domann; William S Dalton
Analysis of MRP mRNA in mitoxantrone-selected, multidrug-resistant human tumor cells.
Biochemical pharmacology 1994;47(9):1601-6.
1993: Bernard W Futscher; L L Blake; J H Gerlach; T M Grogan; W S Dalton
Quantitative polymerase chain reaction analysis of mdr1 mRNA in multiple myeloma cell lines and clinical specimens.
Analytical biochemistry 1993;213(2):414-21.
1993: A F List; C Spier; J Greer; S Wolff; J Hutter; Robert T Dorr; S Salmon; Bernard W Futscher; M Baier; W Dalton
Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(9):1652-60.
1993: Mary K Danks; M R Warmoth; Ellen Friche; B Granzen; B Y Bugg; W G Harker; L A Zwelling; Bernard W Futscher; D P Suttle; William T Beck
Single-strand conformational polymorphism analysis of the M(r) 170,000 isozyme of DNA topoisomerase II in human tumor cells.
Cancer research 1993;53(6):1373-9.
1992: Bernard W Futscher; K Campbell; William S Dalton
Collateral sensitivity to nitrosoureas in multidrug-resistant cells selected with verapamil.
Cancer research 1992;52(18):5013-7.
1992: Mark A Nelson; Bernard W Futscher; M R Loew; George Bowden
Analysis of the Harvey ras gene in cisplatin-initiated mouse skin tumors by polymerase chain reaction and direct DNA sequencing.
Cancer letters 1992;65(1):27-33.
1992: Mark A Nelson; Bernard W Futscher; T Kinsella; J Wymer; George Bowden
Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(14):6398-402.
1992: Bernard W Futscher; R O Pieper; D M Barnes; Israel Hanin; L C Erickson
DNA-damaging and transcription-terminating lesions induced by AF64A in vitro.
Journal of neurochemistry 1992;58(4):1504-9.
1992: Bernard W Futscher; R O Pieper; W S Dalton; L C Erickson
Gene-specific DNA interstrand cross-links produced by nitrogen mustard in the human tumor cell line Colo320HSR.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992;3(4):217-23.
1992: K C Micetich; Bernard W Futscher; D Koch; Richard I Fisher; L C Erickson
Phase I study of streptozocin- and carmustine-sequenced administration in patients with advanced cancer.
Journal of the National Cancer Institute 1992;84(4):256-60.
1992: D T Grabowski; R O Pieper; Bernard W Futscher; Walter A Deutsch; L C Erickson; Mark R Kelley
Expression of ribosomal phosphoprotein PO is induced by antitumor agents and increased in Mer- human tumor cell lines.
Carcinogenesis 1992;13(2):259-63.
1991: R O Pieper; Joseph F Costello; Roger Kroes; Bernard W Futscher; U Marathi; L C Erickson
Direct correlation between methylation status and expression of the human O-6-methylguanine DNA methyltransferase gene.
Cancer communications 1991;3(8):241-53.
1991: R O Pieper; Bernard W Futscher; Q Dong; L C Erickson
Effects of streptozotocin/bis-chloroethylnitrosourea combination therapy on O6-methylguanine DNA methyltransferase activity and mRNA levels in HT-29 cells in vitro.
Cancer research 1991;51(6):1581-5.
1990: N S Vlahos; Bernard W Futscher; N K Hora; Jeffrey M. Trent; L C Erickson
Gene amplification affecting O(6)-alkylguanine-DNA alkyltransferase activity is not detected in nitrosourea resistant or sensitive human cell lines.
Carcinogenesis 1990;11(3):479-83.
1990: R O Pieper; Bernard W Futscher; Q Dong; T M Ellis; L C Erickson
Comparison of O-6-methylguanine DNA methyltransferase (MGMT) mRNA levels in Mer+ and Mer- human tumor cell lines containing the MGMT gene by the polymerase chain reaction technique.
Cancer communications 1990;2(1):13-20.
1990: Bernard W Futscher; L C Erickson
Changes in c-myc and c-fos expression in a human tumor cell line following exposure to bifunctional alkylating agents.
Cancer research 1990;50(1):62-6.
1989: R O Pieper; Bernard W Futscher; L C Erickson
Transcription-terminating lesions induced by bifunctional alkylating agents in vitro.
Carcinogenesis 1989;10(7):1307-14.
1989: Bernard W Futscher; K C Micetich; D M Barnes; Richard I Fisher; L C Erickson
Inhibition of a specific DNA repair system and nitrosourea cytotoxicity in resistant human cancer cells.
Cancer communications 1989;1(1):65-73.