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Ruth Gabizon

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Eran Cohen; Oren S Cohen; Kati Frid; Esther Kahana; Iris Lavon; Ephrat Levy Lahad; Shira Perlberg; Sharon Zeligson; Dana Avrahami; Tamar Canello; Joab Chapman; Ruth Gabizon
Snord 3A: a molecular marker and modulator of prion disease progression.
A Tzour; E Sosial; T Canello; Ruth Gabizon; T Meir; Tally Naveh-Many; Itzhak Nussinovitch
Multiple pathways for high voltage-activated ca(2+) influx in anterior pituitary lactotrophs and somatotrophs.
Tamar Canello; Eran Cohen; Kati Frid; Yael Friedman-Levi; Orli Binyamin; Michal Mizrahi; Ruth Gabizon
Copper is toxic to PrP-ablated mice and exacerbates disease in a mouse model of E200K genetic prion disease.

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All Publications

2013: Eran Cohen; Oren S Cohen; Kati Frid; Esther Kahana; Iris Lavon; Ephrat Levy Lahad; Shira Perlberg; Sharon Zeligson; Dana Avrahami; Tamar Canello; Joab Chapman; Ruth Gabizon
Snord 3A: a molecular marker and modulator of prion disease progression.
PloS one 2013;8(1):e54433.
2013: A Tzour; E Sosial; T Canello; Ruth Gabizon; T Meir; Tally Naveh-Many; Itzhak Nussinovitch
Multiple pathways for high voltage-activated ca(2+) influx in anterior pituitary lactotrophs and somatotrophs.
Journal of neuroendocrinology 2013;25(1):76-86.
2012: Tamar Canello; Eran Cohen; Kati Frid; Yael Friedman-Levi; Orli Binyamin; Michal Mizrahi; Ruth Gabizon
Copper is toxic to PrP-ablated mice and exacerbates disease in a mouse model of E200K genetic prion disease.
Neurobiology of disease 2012;45(3):1010-7.
2012: Yael Friedman-Levi; Oded Abramsky; Herbert Budka; Romana Hoftberger; Tehila Mayer-Sonnenfeld; Haim Ovadia; Ruth Gabizon
Targeting of prion-infected lymphoid cells to the central nervous system accelerates prion infection.
Journal of neuroinflammation 2012;9():58.
2011: Yael Friedman-Levi; Gabor Geza Kovacs; Zeev Meiner; Dana Avrahami; Herbert Budka; Tamar Canello; Kati Frid; Ruth Gabizon
Fatal prion disease in a mouse model of genetic E200K Creutzfeldt-Jakob disease.
PLoS pathogens 2011;7(11):e1002350.
2011: Dana Avrahami; Ruth Gabizon
Age-related alterations affect the susceptibility of mice to prion infection.
Neurobiology of aging 2011;32(11):2006-15.
2011: Zeev Meiner; Esther Kahana; Fanny Baitcher; Amos D Korczyn; Joab Chapman; Oren S Cohen; Ron Milo; Judith Aharon-Perez; Oded Abramsky; Ruth Gabizon; Hanna Rosenmann
Tau and 14-3-3 of genetic and sporadic Creutzfeldt-Jakob disease patients in Israel.
Journal of neurology 2011;258(2):255-62.
2010: Silvia Lisa; Massimiliano Meli; Gema Cabello; Ruth Gabizon; Giorgio Colombo; María Gasset
The structural intolerance of the PrP alpha-fold for polar substitution of the helix-3 methionines.
Cellular and molecular life sciences : CMLS 2010;67(16):2825-38.
2010: Tamar Canello; Kati Frid; Ruth Gabizon; Silvia Lisa; Assaf Friedler; Jackob Moskovitz; María Gasset; Ruth Gabizon
Oxidation of Helix-3 methionines precedes the formation of PK resistant PrP.
PLoS pathogens 2010;6(7):e1000977.
2009: Derek B Oien; Tamar Canello; Ruth Gabizon; Maria Gasset; Brandi L Lundquist; Jeff M Burns; Jackob Moskovitz
Detection of oxidized methionine in selected proteins, cellular extracts and blood serums by novel anti-methionine sulfoxide antibodies.
Archives of biochemistry and biophysics 2009;485(1):35-40.
2008: Tehila Mayer-Sonnenfeld; Dana Avrahami; Yael Friedman-Levi; Ruth Gabizon
Chemically induced accumulation of GAGs delays PrP(Sc) clearance but prolongs prion disease incubation time.
Cellular and molecular neurobiology 2008;28(7):1005-15.
2008: Dana Avrahami; Yael Dayan-Amouyal; Saar Tal; Michal Mincberg; Claytus Davis; Oded Abramsky; Ruth Gabizon
Virus-induced alterations of membrane lipids affect the incorporation of PrP Sc into cells.
Journal of neuroscience research 2008;86(12):2753-62.
2008: Tamar Canello; Roni Engelstein; Ofra Moshel; Konstantinos Xanthopoulos; María E Juanes; Jan Langeveld; Theodoros Sklaviadis; Maria Gasset; Ruth Gabizon
Methionine sulfoxides on PrPSc: a prion-specific covalent signature.
Biochemistry 2008;47(34):8866-73.
2008: Yaron Haviv; Dana Avrahami; Haim Ovadia; Tamir Ben-Hur; Ruth Gabizon; Ronit Sharon
Induced neuroprotection independently from PrPSc accumulation in a mouse model for prion disease treated with simvastatin.
Archives of neurology 2008;65(6):762-75.
2008: Spyros Petrakis; T Irinopoulou; Cynthia H Panagiotidis; Roni Engelstein; J Lindstrom; A Orr-Urtreger; Ruth Gabizon; Nikolaos Grigoriadis; Theodoros Sklaviadis
Cellular prion protein co-localizes with nAChR beta4 subunit in brain and gastrointestinal tract.
The European journal of neuroscience 2008;27(3):612-20.
2007: Yael Friedman-Levi; Haim Ovadia; Romana Hoftberger; Ofira Einstein; Oded Abramsky; Herbert Budka; Ruth Gabizon
Fatal neurological disease in scrapie-infected mice induced for experimental autoimmune encephalomyelitis.
Journal of virology 2007;81(18):9942-9.
2007: Roni Engelstein; Haim Ovadia; Ruth Gabizon
Copaxone interferes with the PrP Sc-GAG interaction.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2007;14(8):877-84.
2006: Michele Halimi; Yael Dayan-Amouyal; Zehavit Kariv-Inbal; Yael Friedman-Levi; Tehila Mayer-Sonnenfeld; Ruth Gabizon
Prion urine comprises a glycosaminoglycan-light chain IgG complex that can be stained by Congo red.
Journal of virological methods 2006;133(2):205-10.
2006: Zehavit Kariv-Inbal; Tamir Ben-Hur; Nikolaos Grigoriadis; Roni Engelstein; Ruth Gabizon
Urine from scrapie-infected hamsters comprises low levels of prion infectivity.
Neuro-degenerative diseases 2006;3(3):123-8.
2005: Tehila Mayer-Sonnenfeld; Marsha Zeigler; Michele Halimi; Yael Dayan; Christian Herzog; Corinne I Lasmezas; Ruth Gabizon
The metabolism of glycosaminoglycans is impaired in prion diseases.
Neurobiology of disease 2005;20(3):738-43.
2005: Zehavit Kariv-Inbal; Michele Halimi; Yael Dayan; Roni Engelstein; Ruth Gabizon
Characterization of light chain immunoglobulin in urine from animals and humans infected with prion diseases.
Journal of neuroimmunology 2005;162(1-2):12-8.
2005: Nuha Hijazi; Zehavit Kariv-Inbal; María Gasset; Ruth Gabizon
PrPSc incorporation to cells requires endogenous glycosaminoglycan expression.
The Journal of biological chemistry 2005;280(17):17057-61.
2005: Roni Engelstein; Nikolaos Grigoriadis; Nigel H Greig; Haim Ovadia; Ruth Gabizon
Inhibition of P53-related apoptosis had no effect on PrP(Sc) accumulation and prion disease incubation time.
Neurobiology of disease 2005;18(2):282-5.
2003: Nuha Hijazi; Yuval Shaked; Hanna Rosenmann; Tamir Ben-Hur; Ruth Gabizon
Copper binding to PrPC may inhibit prion disease propagation.
Brain research 2003;993(1-2):192-200.
2003: Oshrat Schonberger; Lior Horonchik; Ruth Gabizon; Dulce Papy-Garcia; Denis Barritault; Albert Taraboulos
Novel heparan mimetics potently inhibit the scrapie prion protein and its endocytosis.
Biochemical and biophysical research communications 2003;312(2):473-9.
2003: Gideon M Shaked; Roni Engelstein; Inbal Avraham; Esther Kahana; Ruth Gabizon
Dimethyl sulfoxide delays PrP sc accumulation and disease symptoms in prion-infected hamsters.
Brain research 2003;983(1-2):137-43.
2002: Yuval Shaked; Nuha Hijazi; Ruth Gabizon
Doppel and PrP(C) do not share the same membrane microenvironment.
FEBS letters 2002;530(1-3):85-8.
2002: Salit Tzaban; Gilgi Friedlander; Oshrat Schonberger; Lior Horonchik; Yifat Yedidia; Gideon M Shaked; Ruth Gabizon; Albert Taraboulos
Protease-sensitive scrapie prion protein in aggregates of heterogeneous sizes.
Biochemistry 2002;41(42):12868-75.
2002: Gideon M Shaked; Roni Engelstein; Inbal Avraham; Hanna Rosenmann; Ruth Gabizon
Valproic acid treatment results in increased accumulation of prion proteins.
Annals of neurology 2002;52(4):416-20.
2002: Yuval Shaked; Roni Engelstein; Ruth Gabizon
The binding of prion proteins to serum components is affected by detergent extraction conditions.
Journal of neurochemistry 2002;82(1):1-5.
2001: Yuval Shaked; Hanna Rosenmann; Nuha Hijazi; Michele Halimi; Ruth Gabizon
Copper binding to the PrP isoforms: a putative marker of their conformation and function.
Journal of virology 2001;75(17):7872-4.
2001: Gideon M Shaked; Yuval Shaked; Zehavit Kariv-Inbal; Michele Halimi; Inbal Avraham; Ruth Gabizon
A protease-resistant prion protein isoform is present in urine of animals and humans affected with prion diseases.
The Journal of biological chemistry 2001;276(34):31479-82.
2001: Gideon M Shaked; Zeev Meiner; Inbal Avraham; Albert Taraboulos; Ruth Gabizon
Reconstitution of prion infectivity from solubilized protease-resistant PrP and nonprotein components of prion rods.
The Journal of biological chemistry 2001;276(17):14324-8.
2001: Hanna Rosenmann; G Talmor; Michele Halimi; A Yanai; Ruth Gabizon; Zeev Meiner
Prion protein with an E200K mutation displays properties similar to those of the cellular isoform PrP(C).
Journal of neurochemistry 2001;76(6):1654-62.
2000: Gilmor Keshet; O Bar-Peled; David Yaffe; Uri Nudel; Ruth Gabizon
The cellular prion protein colocalizes with the dystroglycan complex in the brain.
Journal of neurochemistry 2000;75(5):1889-97.
2000: Ely Simon; Esther Kahana; Joab Chapman; Therese A Treves; Ruth Gabizon; Hanna Rosenmann; Nelly Zilber; Amos D Korczyn
Creutzfeldt-Jakob disease profile in patients homozygous for the PRNP E200K mutation.
Annals of neurology 2000;47(2):257-60.
1999: Yuval Shaked; Hanna Rosenmann; G Talmor; Ruth Gabizon
A C-terminal-truncated PrP isoform is present in mature sperm.
The Journal of biological chemistry 1999;274(45):32153-8.
1999: A Yanai; Zeev Meiner; I Gahali; Ruth Gabizon; Albert Taraboulos
Subcellular trafficking abnormalities of a prion protein with a disrupted disulfide loop.
FEBS letters 1999;460(1):11-6.
1999: Hanna Rosenmann; Esther Kahana; Amos D Korczyn; I Kahana; Joab Chapman; Ruth Gabizon
Preliminary evidence for anticipation in genetic E200K Creutzfeldt-Jakob disease.
Neurology 1999;53(6):1328-9.
1999: Gideon M Shaked; G Fridlander; Zeev Meiner; Albert Taraboulos; Ruth Gabizon
Protease-resistant and detergent-insoluble prion protein is not necessarily associated with prion infectivity.
The Journal of biological chemistry 1999;274(25):17981-6.
1999: Gilmor Keshet; Haim Ovadia; Albert Taraboulos; Ruth Gabizon
Scrapie-infected mice and PrP knockout mice share abnormal localization and activity of neuronal nitric oxide synthase.
Journal of neurochemistry 1999;72(3):1224-31.
1998: Zeev Meiner; Ruth Gabizon
[A new variant of Creutzfeldt-Jakob disease and its relation to bovine spongiform encephalopathy (BSE) in Great Britain].
Harefuah 1998;134(6):465-8.
1998: Hanna Rosenmann; Jacob Vardi; Yoram Finkelstein; Joab Chapman; Ruth Gabizon
Identification in Israel of 2 Jewish Creutzfeld-Jakob disease patients with a 178 mutation at their PrP gene.
Acta neurologica Scandinavica 1998;97(3):184-7.
1998: S Caspi; Michele Halimi; A Yanai; S B Sasson; Albert Taraboulos; Ruth Gabizon
The anti-prion activity of Congo red. Putative mechanism.
The Journal of biological chemistry 1998;273(6):3484-9.
1997: Hanna Rosenmann; Michele Halimi; I Kahana; Iftah Biran; Ruth Gabizon
Differential allelic expression of PrP mRNA in carriers of the E200K mutation.
Neurology 1997;49(3):851-6.
1997: Hanna Rosenmann; Zeev Meiner; Esther Kahana; Michele Halimi; E Lenetsky; Oded Abramsky; Ruth Gabizon
Detection of 14-3-3 protein in the CSF of genetic Creutzfeldt-Jakob disease.
Neurology 1997;49(2):593-5.
1997: Zeev Meiner; Ruth Gabizon; Stanley B Prusiner
Familial Creutzfeldt-Jakob disease. Codon 200 prion disease in Libyan Jews.
Medicine 1997;76(4):227-37.
1997: Ruth Gabizon; Albert Taraboulos
Of mice and (mad) cows--transgenic mice help to understand prions.
Trends in genetics : TIG 1997;13(7):264-9.
1997: G Friedman; Ruth Gabizon; Arie Ben-Yehuda
Apolipoprotein Eepsilon4 allele, a risk factor for late onset nonfamilial Alzheimer's disease among Israeli Jews.
Archives of gerontology and geriatrics 1997;24(2):175-81.
1996: Glenn C Telling; Piero Parchi; Stephen J DeArmond; Pietro Cortelli; P Montagna; Ruth Gabizon; James A Mastrianni; E Lugaresi; P Gambetti; Stanley B Prusiner
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity.
Science (New York, N.Y.) 1996;274(5295):2079-82.
1996: H Ovadia; Hanna Rosenmann; Elias Shezen; Michele Halimi; I Ofran; Ruth Gabizon
Effect of scrapie infection on the activity of neuronal nitric-oxide synthase in brain and neuroblastoma cells.
The Journal of biological chemistry 1996;271(28):16856-61.
1996: Ruth Gabizon; Glenn C Telling; Zeev Meiner; Michele Halimi; I Kahana; Stanley B Prusiner
Insoluble wild-type and protease-resistant mutant prion protein in brains of patients with inherited prion disease.
Nature medicine 1996;2(1):59-64.
1995: Kiyotoshi Kaneko; David Peretz; K M Pan; T C Blochberger; Holger Wille; Ruth Gabizon; O H Griffith; Fred Cohen; Michael A Baldwin; Stanley B Prusiner
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):11160-4.
1995: Glenn C Telling; Michael Scott; James A Mastrianni; Ruth Gabizon; M Torchia; Fred Cohen; Stephen J DeArmond; Stanley B Prusiner
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein.
Cell 1995;83(1):79-90.
1995: S Spudich; James A Mastrianni; M Wrensch; Ruth Gabizon; Zeev Meiner; I Kahana; Hanna Rosenmann; Esther Kahana; Stanley B Prusiner
Complete penetrance of Creutzfeldt-Jakob disease in Libyan Jews carrying the E200K mutation in the prion protein gene.
Molecular medicine (Cambridge, Mass.) 1995;1(6):607-13.
1994: Ruth Gabizon; H Rosenman; Zeev Meiner; I Kahana; Esther Kahana; Yin Yao Shugart; J Ott; Stanley B Prusiner
Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994;343(1306):385-90.
1994: Ruth Gabizon; Michele Halimi; Zeev Meiner
Genetics and biochemistry of Creutzfeldt-Jakob disease in Libyan Jews.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1994;48(8-9):385-90.
1993: Y Goldhammer; Ruth Gabizon; Zeev Meiner; M Sadeh
An Israeli family with Gerstmann-Sträussler-Scheinker disease manifesting the codon 102 mutation in the prion protein gene.
Neurology 1993;43(12):2718-9.
1993: Ruth Gabizon; Zeev Meiner; Michele Halimi; Shmuel A Ben-Sasson
Heparin-like molecules bind differentially to prion-proteins and change their intracellular metabolic fate.
Journal of cellular physiology 1993;157(2):319-25.
1993: Ruth Gabizon; Hanna Rosenmann; Zeev Meiner; I Kahana; Esther Kahana; Yin Yao Shugart; J Ott; Stanley B Prusiner
Mutation and polymorphism of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease (CJD).
American journal of human genetics 1993;53(4):828-35.
1993: Stanley B Prusiner; Darlene Groth; A Serban; Neil stahl; Ruth Gabizon
Attempts to restore scrapie prion infectivity after exposure to protein denaturants.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2793-7.
1992: Zeev Meiner; Michele Halimi; R D Polakiewicz; Stanley B Prusiner; Ruth Gabizon
Presence of prion protein in peripheral tissues of Libyan Jews with Creutzfeldt-Jakob disease.
Neurology 1992;42(7):1355-60.
1991: Karen K. Hsiao Ashe; Zeev Meiner; Esther Kahana; C Cass; I Kahana; D Avrahami; G Scarlato; Oded Abramsky; Stanley B Prusiner; Ruth Gabizon
Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease.
The New England journal of medicine 1991;324(16):1091-7.
1991: Zeev Meiner; Ruth Gabizon; Esther Kahana
[Creutzfeldt-Jacob disease: etiology and epidemiology].
Harefuah 1991;120(1):19-22.
1990: Ruth Gabizon; Stanley B Prusiner
Prion liposomes.
The Biochemical journal 1990;266(1):1-14.
1989: Ruth Gabizon; M P McKinley; Darlene Groth; David Westaway; Stephen J DeArmond; G A Carlson; Stanley B Prusiner
Immunoaffinity purification and neutralization of scrapie prions.
Progress in clinical and biological research 1989;317():583-600.
1988: Ruth Gabizon; M P McKinley; Darlene Groth; Stanley B Prusiner
Immunoaffinity purification and neutralization of scrapie prion infectivity.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(18):6617-21.
1988: C G Bellinger-Kawahara; E Kempner; Darlene Groth; Ruth Gabizon; Stanley B Prusiner
Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da.
Virology 1988;164(2):537-41.
1988: Ruth Gabizon; M P McKinley; Darlene Groth; L Kenaga; Stanley B Prusiner
Properties of scrapie prion protein liposomes.
The Journal of biological chemistry 1988;263(10):4950-5.
1988: Ruth Gabizon; M P McKinley; Stanley B Prusiner
Properties of scrapie prion proteins in liposomes and amyloid rods.
Ciba Foundation symposium 1988;135():182-96.
1987: Ruth Gabizon; M P McKinley; Stanley B Prusiner
Purified prion proteins and scrapie infectivity copartition into liposomes.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(12):4017-21.
1987: Stanley B Prusiner; Ruth Gabizon; M P McKinley
On the biology of prions.
Acta neuropathologica 1987;72(4):299-314.