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Mihaela Gadjeva

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Thomas Reidy; Alexander Rittenberg; Samantha D'Ortona; Markryan Dwyer; Gerald Pier; Mihaela Gadjeva
Homotrimeric macrophage migration inhibitory factor (MIF) drives inflammatory responses in the corneal epithelium by promoting caveolin-rich platform assembly in response to infection.
Tanweer Zaidi; Samantha D'Ortona; Raina Fichorova; Gerald Pier; Thomas Reidy; Mihaela Gadjeva
CD74 deficiency ameliorates Pseudomonas aeruginosa-induced ocular infection.
David Skurnik; Massimo Merighi; Martha Grout; Mihaela Gadjeva; Tomas Maira-Litran; Maria Ericsson; Donald A Goldmann; Susan S Huang; Rupak Datta; Jean C Lee; Gerald B Pier
Animal and human antibodies to distinct Staphylococcus aureus antigens mutually neutralize opsonic killing and protection in mice.

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All Publications

2013: Thomas Reidy; Alexander Rittenberg; Samantha D'Ortona; Markryan Dwyer; Gerald Pier; Mihaela Gadjeva
Homotrimeric macrophage migration inhibitory factor (MIF) drives inflammatory responses in the corneal epithelium by promoting caveolin-rich platform assembly in response to infection.
The Journal of biological chemistry 2013;288(12):8269-78.
2011: Tanweer Zaidi; Samantha D'Ortona; Raina Fichorova; Gerald Pier; Thomas Reidy; Mihaela Gadjeva
CD74 deficiency ameliorates Pseudomonas aeruginosa-induced ocular infection.
Scientific reports 2011;1():58.
2010: David Skurnik; Massimo Merighi; Martha Grout; Mihaela Gadjeva; Tomas Maira-Litran; Maria Ericsson; Donald A Goldmann; Susan S Huang; Rupak Datta; Jean C Lee; Gerald B Pier
Animal and human antibodies to distinct Staphylococcus aureus antigens mutually neutralize opsonic killing and protection in mice.
The Journal of clinical investigation 2010;120(9):3220-33.
2010: Mihaela Kojouharova; Kenneth Reid; Mihaela Gadjeva
New insights into the molecular mechanisms of classical complement activation.
Molecular immunology 2010;47(13):2154-60.
2010: Mihaela Gadjeva; Jill Nagashima; Tanweer Zaidi; Robert A Mitchell; Gerald B Pier
Inhibition of macrophage migration inhibitory factor ameliorates ocular Pseudomonas aeruginosa-induced keratitis.
PLoS pathogens 2010;6(3):e1000826.
2010: Mihaela Gadjeva; Catherine Paradis-Bleau; Gregory P Priebe; Raina Fichorova; Gerald B Pier
Caveolin-1 modifies the immunity to Pseudomonas aeruginosa.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(1):296-302.
2010: Akinobu Kamei; Andrew Y Koh; Mihaela Gadjeva; Gregory P Priebe; Stephen Lory; Gerald B Pier
Analysis of acquisition of Pseudomonas aeruginosa gastrointestinal mucosal colonization and horizontal transmission in a murine model.
The Journal of infectious diseases 2010;201(1):71-80.
2009: Milan Bajmoczi; Mihaela Gadjeva; Seth L Alper; Gerald B Pier; David E Golan
Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa.
American journal of physiology. Cell physiology 2009;297(2):C263-77.
2009: Marieta M Ruseva; Martin Kolev; Frederik Dagnaes-Hansen; Soren B Hansen; Kazue Takahashi; AB Ezekowitz; Steffen Thiel; Jens C Jensenius; Mihaela Gadjeva
Mannan-binding lectin deficiency modulates the humoral immune response dependent on the genetic environment.
Immunology 2009;127(2):279-88.
2009: Steffen Thiel; Mihaela Gadjeva
Humoral pattern recognition molecules: mannan-binding lectin and ficolins.
Advances in experimental medicine and biology 2009;653():58-73.
2008: Lubka T Roumenina; Krustyo T Popov; Svetlana V Bureeva; Mihaela S Kojouharova; Mihaela Gadjeva; Shweta Rabheru; Roshni Thakrar; Alexander Kaplun; Uday Kishore
Interaction of the globular domain of human C1q with Salmonella typhimurium lipopolysaccharide.
Biochimica et biophysica acta 2008;1784(9):1271-6.
2008: Victoria L Campodónico; Mihaela Gadjeva; Catherine Paradis-Bleau; Ahmet Uluer; Gerald B Pier
Airway epithelial control of Pseudomonas aeruginosa infection in cystic fibrosis.
Trends in molecular medicine 2008;14(3):120-33.
2007: Mihaela Gadjeva; Yanyan Wang; Bruce H Horwitz
NF-kappaB p50 and p65 subunits control intestinal homeostasis.
European journal of immunology 2007;37(9):2509-17.
2007: Steffen Thiel; R Steffensen; I J Christensen; W K Ip; Y L Lau; I J M Reason; Hans Eiberg; Mihaela Gadjeva; Marieta M Ruseva; Jens C Jensenius
Deficiency of mannan-binding lectin associated serine protease-2 due to missense polymorphisms.
Genes and immunity 2007;8(2):154-63.
2007: Rohit Ghai; Patrick Waters; Lubka T Roumenina; Mihaela Gadjeva; Mihaela S Kojouharova; Kenneth B M Reid; Robert B Sim; Uday Kishore
C1q and its growing family.
Immunobiology 2007;212(4-5):253-66.
2006: Alexandra S Zlatarova; Marieta Rouseva; Lubka T Roumenina; Mihaela Gadjeva; Martin Kolev; Ivan Dobrev; Neli Olova; Rohit Ghai; Jens C Jensenius; Kenneth B M Reid; Uday Kishore; Mihaela S Kojouharova
Existence of different but overlapping IgG- and IgM-binding sites on the globular domain of human C1q.
Biochemistry 2006;45(33):9979-88.
2006: Lubka T Roumenina; Marieta M Ruseva; Alexandra S Zlatarova; Rohit Ghai; Martin Kolev; Neli Olova; Mihaela Gadjeva; Alok Agrawal; Barbara Bottazzi; Alberto Mantovani; Kenneth B M Reid; Uday Kishore; Mihaela S Kojouharova
Interaction of C1q with IgG1, C-reactive protein and pentraxin 3: mutational studies using recombinant globular head modules of human C1q A, B, and C chains.
Biochemistry 2006;45(13):4093-104.
2006: Michal F Tomczak; Mihaela Gadjeva; Yan Yan Wang; Ketorah Brown; Ioanna G Maroulakou; Philip Tsichlis; Susan E Erdman; James G Fox; Bruce H Horwitz
Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with Helicobacter hepaticus.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(2):1244-51.
2005: Lubka T Roumenina; Alexander A Kantardjiev; Boris P Atanasov; Patrick Waters; Mihaela Gadjeva; Kenneth B M Reid; Alberto Mantovani; Uday Kishore; Mihaela S Kojouharova
Role of Ca2+ in the electrostatic stability and the functional activity of the globular domain of human C1q.
Biochemistry 2005;44(43):14097-109.
2005: Mette Møller-Kristensen; W Wang; Marieta M Ruseva; Steffen Thiel; S Nielsen; Kazue Takahashi; Lei Shi; AB Ezekowitz; Jens C Jensenius; Mihaela Gadjeva
Mannan-binding lectin recognizes structures on ischaemic reperfused mouse kidneys and is implicated in tissue injury.
Scandinavian journal of immunology 2005;61(5):426-34.
2004: Mihaela Gadjeva; Søren R Paludan; Steffen Thiel; V Slavov; Marieta M Ruseva; Kristina Eriksson; G-B Löwhagen; Lei Shi; Kazue Takahashi; AB Ezekowitz; Jens C Jensenius
Mannan-binding lectin modulates the response to HSV-2 infection.
Clinical and experimental immunology 2004;138(2):304-11.
2004: Mihaela Gadjeva; Michal F Tomczak; Ming Zhang; Yan Yan Wang; Karen Dull; Arlin Rogers; Susan E Erdman; James G Fox; Michael Carroll; Bruce H Horwitz
A role for NF-kappa B subunits p50 and p65 in the inhibition of lipopolysaccharide-induced shock.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5786-93.
2004: Uday Kishore; Rohit Ghai; Trevor J Greenhough; Annette K Shrive; Domenico Marco Bonifati; Mihaela Gadjeva; Patrick Waters; Mihaela S Kojouharova; Trinad Chakraborty; Alok Agrawal
Structural and functional anatomy of the globular domain of complement protein C1q.
Immunology letters 2004;95(2):113-28.
2004: Mihaela Gadjeva; Kazue Takahashi; Steffen Thiel
Mannan-binding lectin--a soluble pattern recognition molecule.
Molecular immunology 2004;41(2-3):113-21.
2004: Mihaela S Kojouharova; Mihaela Gadjeva; Ivanka G Tsacheva; Alexandra S Zlatarova; Lubka T Roumenina; Magdalena I Tchorbadjieva; Boris P Atanasov; Patrick Waters; Britta C Urban; Robert B Sim; Kenneth B M Reid; Uday Kishore
Mutational analyses of the recombinant globular regions of human C1q A, B, and C chains suggest an essential role for arginine and histidine residues in the C1q-IgG interaction.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4351-8.
2004: Mihaela Gadjeva; Steffen Thiel; Jens C Jensenius
Assays for the mannan-binding lectin pathway.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2004;Chapter 13():Unit 13.6.
2003: Admar Verschoor; Mark Alan Brockman; Mihaela Gadjeva; David M Knipe; Michael C Carroll
Myeloid C3 determines induction of humoral responses to peripheral herpes simplex virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5363-71.
2003: Kristian Stengaard-Pedersen; Steffen Thiel; Mihaela Gadjeva; Mette Møller-Kristensen; Rikke Sørensen; Lise T Jensen; Anders G Sjøholm; Lars Fugger; Jens C Jensenius
Inherited deficiency of mannan-binding lectin-associated serine protease 2.
The New England journal of medicine 2003;349(6):554-60.
2002: Mihaela Gadjeva; Admar Verschoor; Mark Alan Brockman; Heather Jezak; Li Ming Shen; David M Knipe; Michael C Carroll
Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5489-95.
2001: Mihaela Gadjeva; Steffen Thiel; Jens C Jensenius
The mannan-binding-lectin pathway of the innate immune response.
Current opinion in immunology 2001;13(1):74-8.