Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Matthias Gaestel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Phenomena

Phosphorylation

Physiology

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Liu Tiegang; Guevara Oscar E; Warburton Rod R; Hill Nicholas S; Gaestel Matthias; Kayyali Usamah S
Modulation of HSP27 alters hypoxia-induced endothelial permeability and related signaling pathways.
Gorog Diana A; Jabr Rita I; Tanno Masaya; Sarafraz Negin; Clark James E; Fisher Simon G; Cao Xou Bin; Bellahcene Mohamed; Dighe Kushal; Kabir Alamgir M N; Quinlan Roy A; Kato Kanefusa; Gaestel Matthias; Marber Michael S; Heads Richard J
MAPKAPK-2 modulates p38-MAPK localization and small heat shock protein phosphorylation but does not mediate the injury associated with p38-MAPK activation during myocardial ischemia.
Gaestel Matthias; Kotlyarov Alexey; Kracht Michael
Targeting innate immunity protein kinase signalling in inflammation.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Matthias Gaestel (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Liu Tiegang; Guevara Oscar E; Warburton Rod R; Hill Nicholas S; Gaestel Matthias; Kayyali Usamah S
Modulation of HSP27 alters hypoxia-induced endothelial permeability and related signaling pathways.
Journal of cellular physiology 2009;220(3):600-10.
2009: Gorog Diana A; Jabr Rita I; Tanno Masaya; Sarafraz Negin; Clark James E; Fisher Simon G; Cao Xou Bin; Bellahcene Mohamed; Dighe Kushal; Kabir Alamgir M N; Quinlan Roy A; Kato Kanefusa; Gaestel Matthias; Marber Michael S; Heads Richard J
MAPKAPK-2 modulates p38-MAPK localization and small heat shock protein phosphorylation but does not mediate the injury associated with p38-MAPK activation during myocardial ischemia.
Cell stress & chaperones 2009;14(5):477-89.
2009: Gaestel Matthias; Kotlyarov Alexey; Kracht Michael
Targeting innate immunity protein kinase signalling in inflammation.
Nature reviews. Drug discovery 2009;8(6):480-99.
2009: Tudor Corina; Marchese Francesco P; Hitti Edward; Aubareda Anna; Rawlinson Lesley; Gaestel Matthias; Blackshear Perry J; Clark Andrew R; Saklatvala Jeremy; Dean Jonathan L E
The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophages.
FEBS letters 2009;583(12):1933-8.
2009: Zhu Jianzhong; Wu Xianzhu; Goel Suchi; Gowda Nagaraj M; Kumar Sanjeev; Krishnegowda Gowdahalli; Mishra Gourav; Weinberg Rebecca; Li Guangfu; Gaestel Matthias; Muta Tatsushi; Gowda D Channe
MAPK-activated protein kinase 2 differentially regulates plasmodium falciparum glycosylphosphatidylinositol-induced production of tumor necrosis factor-{alpha} and interleukin-12 in macrophages.
The Journal of biological chemistry 2009;284(23):15750-61.
2009: Schwermann Jessica; Rathinam Chozhavendan; Schubert Maria; Schumacher Stefanie; Noyan Fatih; Koseki Haruhiko; Kotlyarov Alexey; Klein Christoph; Gaestel Matthias
MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells.
The EMBO journal 2009;28(10):1392-406.
2009: Mikkelsen Susie S; Jensen Søren B; Chiliveru Srikanth; Melchjorsen Jesper; Julkunen Ilkka; Gaestel Matthias; Arthur J Simon C; Flavell Richard A; Ghosh Sankar; Paludan Søren R
RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1.
The Journal of biological chemistry 2009;284(16):10774-82.
2009: Funding Anne T; Johansen Claus; Gaestel Matthias; Bibby Bo M; Lilleholt Louise L; Kragballe Knud; Iversen Lars
Reduced oxazolone-induced skin inflammation in MAPKAP kinase 2 knockout mice.
The Journal of investigative dermatology 2009;129(4):891-8.
2009: Zimnik Susan; Gaestel Matthias; Niedenthal Rainer
Mutually exclusive STAT1 modifications identified by Ubc9/substrate dimerization-dependent SUMOylation.
Nucleic acids research 2009;37(4):e30.
2009: Skokowa Julia; Lan Dan; Thakur Basant Kumar; Wang Fei; Gupta Kshama; Cario Gunnar; Brechlin Annette Müller; Schambach Axel; Hinrichsen Lars; Meyer Gustav; Gaestel Matthias; Stanulla Martin; Tong Qiang; Welte Karl
NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway.
Nature medicine 2009;15(2):151-8.
2009: Gaestel Matthias; Kracht Michael
Peptides as signaling inhibitors for mammalian MAP kinase cascades.
Current pharmaceutical design 2009;15(21):2471-80.
2009: Damarla Mahendra; Hasan Emile; Boueiz Adel; Le Anne; Pae Hyun Hae; Montouchet Calypso; Kolb Todd; Simms Tiffany; Myers Allen; Kayyali Usamah S; Gaestel Matthias; Peng Xinqi; Reddy Sekhar P; Damico Rachel; Hassoun Paul M
Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury.
PloS one 2009;4(2):e4600.
2008: Thomas Tobias; Hitti Edward; Kotlyarov Alexey; Potschka Heidrun; Gaestel Matthias
MAP-kinase-activated protein kinase 2 expression and activity is induced after neuronal depolarization.
The European journal of neuroscience 2008;28(4):642-54.
2008: Thomas Tobias; Timmer Marco; Cesnulevicius Konstantin; Hitti Edward; Kotlyarov Alexey; Gaestel Matthias
MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation--relevance in a mouse model of Parkinson's disease.
Journal of neurochemistry 2008;105(5):2039-52.
2008: Park Joon-Keun; Ronkina Natalia; Höft Andreas; Prohl Corinna; Menne Jan; Gaestel Matthias; Haller Hermann; Meier Matthias
Deletion of MK2 signalling in vivo inhibits small Hsp phosphorylation but not diabetic nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008;23(6):1844-53.
2008: Mendoza Heidi; Campbell David G; Burness Kerry; Hastie James; Ronkina Natalia; Shim Jae-Hyuck; Arthur J Simon C; Davis Roger J; Gaestel Matthias; Johnson Gary L; Ghosh Sankar; Cohen Philip
Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex.
The Biochemical journal 2008;409(3):711-22.
2008: Gaestel Matthias
Specificity of signaling from MAPKs to MAPKAPKs: kinases' tango nuevo.
Frontiers in bioscience : a journal and virtual library 2008;13():6050-9.
2008: Ronkina Natalia; Kotlyarov Alexey; Gaestel Matthias
MK2 and MK3--a pair of isoenzymes?
Frontiers in bioscience : a journal and virtual library 2008;13():5511-21.
2007: Zaru Rossana; Ronkina Natalia; Gaestel Matthias; Arthur J Simon C; Watts Colin
The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways.
Nature immunology 2007;8(11):1227-35.
2007: Jagavelu Kumaravelu; Tietge Uwe J F; Gaestel Matthias; Drexler Helmut; Schieffer Bernhard; Bavendiek Udo
Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice.
Circulation research 2007;101(11):1104-12.
2007: Liu Tiegang; Warburton Rod R; Guevara Oscar E; Hill Nicholas S; Fanburg Barry L; Gaestel Matthias; Kayyali Usamah S
Lack of MK2 inhibits myofibroblast formation and exacerbates pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2007;37(5):507-17.
2007: Gorska Magdalena M; Liang Qiaoling; Stafford Susan J; Goplen Nicolas; Dharajiya Nilesh; Guo Lei; Sur Sanjiv; Gaestel Matthias; Alam Rafeul
MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation.
The Journal of experimental medicine 2007;204(7):1637-52.
2007: Thuraisingam Thusanth; Xu Yong Zhong; Moisan Jacques; Lachance Claude; Garnon James; Di Marco Sergio; Gaestel Matthias; Radzioch Danuta
Distinct role of MAPKAPK-2 in the regulation of TNF gene expression by Toll-like receptor 7 and 9 ligands.
Molecular immunology 2007;44(14):3482-91.
2007: Wu Yue; Zhan Lijun; Ai Youxi; Hannigan Micheal; Gaestel Matthias; Huang Chi-Kuang; Madri Joseph A
MAPKAPK2-mediated LSP1 phosphorylation and FMLP-induced neutrophil polarization.
Biochemical and biophysical research communications 2007;358(1):170-5.
2007: Sousa Anne Marie; Liu Tiegang; Guevara Oscar; Stevens Joanne; Fanburg Barry L; Gaestel Matthias; Toksoz Deniz; Kayyali Usamah S
Smooth muscle alpha-actin expression and myofibroblast differentiation by TGFbeta are dependent upon MK2.
Journal of cellular biochemistry 2007;100(6):1581-92.
2007: Ehlting Christian; Lai Wi S; Schaper Fred; Brenndörfer Erwin D; Matthes Raphaela-Jessica; Heinrich Peter C; Ludwig Stephan; Blackshear Perry J; Gaestel Matthias; Häussinger Dieter; Bode Johannes G
Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-alpha involves activation of the MKK6/p38MAPK/MK2 cascade.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):2813-26.
2007: Jakobs Astrid; Koehnke Jesko; Himstedt Fabian; Funk Martin; Korn Bernhard; Gaestel Matthias; Niedenthal Rainer
Ubc9 fusion-directed SUMOylation (UFDS): a method to analyze function of protein SUMOylation.
Nature methods 2007;4(3):245-50.
2007: Ronkina N; Kotlyarov A; Dittrich-Breiholz O; Kracht M; Hitti E; Milarski K; Askew R; Marusic S; Lin L-L; Gaestel M; Telliez J-B
The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.
Molecular and cellular biology 2007;27(1):170-81.
2007: Jakobs Astrid; Himstedt Fabian; Funk Martin; Korn Bernhard; Gaestel Matthias; Niedenthal Rainer
Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation.
Nucleic acids research 2007;35(17):e109.
2006: Kant Shashi; Schumacher Stefanie; Singh Manvendra Kumar; Kispert Andreas; Kotlyarov Alexey; Gaestel Matthias
Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.
The Journal of biological chemistry 2006;281(46):35511-9.
2006: Rousseau Simon; Dolado Ignacio; Beardmore Victoria; Shpiro Natalia; Marquez Rudolfo; Nebreda Angel R; Arthur J Simon C; Case Lauren M; Tessier-Lavigne Marc; Gaestel Matthias; Cuenda Ana; Cohen Philip
CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway.
Cellular signalling 2006;18(11):1897-905.
2006: Vertii Anastassiia; Hakim Cosima; Kotlyarov Alexey; Gaestel Matthias
Analysis of properties of small heat shock protein Hsp25 in MAPK-activated protein kinase 2 (MK2)-deficient cells: MK2-dependent insolubilization of Hsp25 oligomers correlates with susceptibility to stress.
The Journal of biological chemistry 2006;281(37):26966-75.
2006: Bellahcene Mohamed; Jacquet Sebastien; Cao Xue B; Tanno Masaya; Haworth Robert S; Layland Joanne; Kabir Alamgir M; Gaestel Matthias; Davis Roger J; Flavell Richard A; Shah Ajay M; Avkiran Metin; Marber Michael S
Activation of p38 mitogen-activated protein kinase contributes to the early cardiodepressant action of tumor necrosis factor.
Journal of the American College of Cardiology 2006;48(3):545-55.
2006: Hegen Martin; Gaestel Matthias; Nickerson-Nutter Cheryl L; Lin Lih-Ling; Telliez Jean-Baptiste
MAPKAP kinase 2-deficient mice are resistant to collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1913-7.
2006: Culbert Ainsley A; Skaper Stephen D; Howlett David R; Evans Nicholas A; Facci Laura; Soden Peter E; Seymour Zoe M; Guillot Florence; Gaestel Matthias; Richardson Jill C
MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.
The Journal of biological chemistry 2006;281(33):23658-67.
2006: Tietz Anne Barbara; Malo Antje; Diebold Joachim; Kotlyarov Alexey; Herbst Andreas; Kolligs Frank T; Brandt-Nedelev Barbara; Halangk Walter; Gaestel Matthias; Göke Burkhard; Schäfer Claus
Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(6):G1298-306.
2006: Moisan J; Camateros P; Thuraisingam T; Marion D; Koohsari H; Martin P; Boghdady M L; Ding A; Gaestel M; Guiot M C; Martin J G; Radzioch D
TLR7 ligand prevents allergen-induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathway.
American journal of physiology. Lung cellular and molecular physiology 2006;290(5):L987-95.
2006: Hitti Edward; Iakovleva Tatiana; Brook Matthew; Deppenmeier Stefanie; Gruber Achim D; Radzioch Danuta; Clark Andrew R; Blackshear Perry J; Kotlyarov Alexey; Gaestel Matthias
Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element.
Molecular and cellular biology 2006;26(6):2399-407.
2006: Gaestel Matthias
MAPKAP kinases - MKs - two's company, three's a crowd.
Nature reviews. Molecular cell biology 2006;7(2):120-30.
2006: Wang XiaoZhe; Khaleque Md Abdul; Zhao Mei Juan; Zhong Rong; Gaestel Matthias; Calderwood Stuart K
Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding.
The Journal of biological chemistry 2006;281(2):782-91.
2006: Gaestel M
Molecular chaperones in signal transduction.
Handbook of experimental pharmacology 2006;(172):93-109.
2005: An Steven S; Pennella Corin M; Gonnabathula Achuta; Chen Jianxin; Wang Ning; Gaestel Matthias; Hassoun Paul M; Fredberg Jeffrey J; Kayyali Usamah S
Hypoxia alters biophysical properties of endothelial cells via p38 MAPK- and Rho kinase-dependent pathways.
American journal of physiology. Cell physiology 2005;289(3):C521-30.
2005: Weber Hans Oliver; Ludwig Robert L; Morrison Deborah; Kotlyarov Alexey; Gaestel Matthias; Vousden Karen H
HDM2 phosphorylation by MAPKAP kinase 2.
Oncogene 2005;24(12):1965-72.
2005: Li Yongzhong; Batra Sandeep; Sassano Antonella; Majchrzak Beata; Levy David E; Gaestel Matthias; Fish Eleanor N; Davis Roger J; Platanias Leonidas C
Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons.
The Journal of biological chemistry 2005;280(11):10001-10.
2004: Schumacher Stefanie; Laass Kathrin; Kant Shashi; Shi Yu; Visel Axel; Gruber Achim D; Kotlyarov Alexey; Gaestel Matthias
Scaffolding by ERK3 regulates MK5 in development.
The EMBO journal 2004;23(24):4770-9.
2004: An Steven S; Fabry Ben; Mellema Mathew; Bursac Predrag; Gerthoffer William T; Kayyali Usamah S; Gaestel Matthias; Shore Stephanie A; Fredberg Jeffrey J
Role of heat shock protein 27 in cytoskeletal remodeling of the airway smooth muscle cell.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(5):1701-13.
2004: Yannoni Yvonne M; Gaestel Matthias; Lin Lih-Ling
P66(ShcA) interacts with MAPKAP kinase 2 and regulates its activity.
FEBS letters 2004;564(1-2):205-11.
2004: Wu Yue; Hannigan Michael O; Kotlyarov Alexey; Gaestel Matthias; Wu Dianqing; Huang Chi-Kuang
A requirement of MAPKAPK2 in the uropod localization of PTEN during FMLP-induced neutrophil chemotaxis.
Biochemical and biophysical research communications 2004;316(3):666-72.
2004: Sawitzki Birgit; Kieselbach Brit; Fisser Marion; Meisel Christian; Vogt Katrin; Gaestel Matthias; Lehmann Manfred; Risch Kirsten; Grütz Gerald; Volk Hans-Dieter
IFN-gamma regulation in anti-CD4 antibody-induced T cell unresponsiveness.
Journal of the American Society of Nephrology : JASN 2004;15(3):695-703.
2004: Li Yongzhong; Sassano Antonella; Majchrzak Beata; Deb Dilip K; Levy David E; Gaestel Matthias; Nebreda Angel R; Fish Eleanor N; Platanias Leonidas C
Role of p38alpha Map kinase in Type I interferon signaling.
The Journal of biological chemistry 2004;279(2):970-9.
2003: Shi Yu; Kotlyarov Alexey; Laabeta Kathrin; Gruber Achim D; Butt Elke; Marcus Katrin; Meyer Helmut E; Friedrich Anke; Volk Hans-Dieter; Gaestel Matthias
Elimination of protein kinase MK5/PRAK activity by targeted homologous recombination.
Molecular and cellular biology 2003;23(21):7732-41.
2003: Stromer Thusnelda; Ehrnsperger Monika; Gaestel Matthias; Buchner Johannes
Analysis of the interaction of small heat shock proteins with unfolding proteins.
The Journal of biological chemistry 2003;278(20):18015-21.
2003: Bollig Frank; Winzen Reinhard; Gaestel Matthias; Kostka Susanne; Resch Klaus; Holtmann Helmut
Affinity purification of ARE-binding proteins identifies polyA-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization.
Biochemical and biophysical research communications 2003;301(3):665-70.
2002: Kontoyiannis Dimitris; Boulougouris George; Manoloukos Menelaos; Armaka Maria; Apostolaki Maria; Pizarro Theresa; Kotlyarov Alexey; Forster Irmgard; Flavell Richard; Gaestel Matthias; Tsichlis Philip; Cominelli Fabio; Kollias George
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease.
The Journal of experimental medicine 2002;196(12):1563-74.
2002: Rousseau Simon; Morrice Nick; Peggie Mark; Campbell David G; Gaestel Matthias; Cohen Philip
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs.
The EMBO journal 2002;21(23):6505-14.
2002: Kotlyarov A; Gaestel M
Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?
Biochemical Society transactions 2002;30(Pt 6):959-63.
2002: Wang Xinkang; Xu Lin; Wang Hugh; Young Peter R; Gaestel Matthias; Feuerstein Giora Z
Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice.
The Journal of biological chemistry 2002;277(46):43968-72.
2002: Kayyali Usamah S; Pennella Corin M; Trujillo Carolina; Villa Otto; Gaestel Matthias; Hassoun Paul M
Cytoskeletal changes in hypoxic pulmonary endothelial cells are dependent on MAPK-activated protein kinase MK2.
The Journal of biological chemistry 2002;277(45):42596-602.
2002: Shi Yu; Gaestel Matthias
In the cellular garden of forking paths: how p38 MAPKs signal for downstream assistance.
Biological chemistry 2002;383(10):1519-36.
2002: Kotlyarov Alexey; Yannoni Yvonne; Fritz Susann; Laass Kathrin; Telliez Jean-Baptiste; Pitman Deborah; Lin Lih-Ling; Gaestel Matthias
Distinct cellular functions of MK2.
Molecular and cellular biology 2002;22(13):4827-35.
2002: Lehner Martin D; Schwoebel Frank; Kotlyarov Alexey; Leist Marcel; Gaestel Matthias; Hartung Thomas
Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4667-73.
2002: Neininger Armin; Kontoyiannis Dimitris; Kotlyarov Alexey; Winzen Reinhard; Eckert Rolf; Volk Hans-Dieter; Holtmann Helmut; Kollias George; Gaestel Matthias
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels.
The Journal of biological chemistry 2002;277(5):3065-8.
2002: Haydon Claire E; Watt Peter W; Morrice Nick; Knebel Axel; Gaestel Matthias; Cohen Philip
Identification of a phosphorylation site on skeletal muscle myosin light chain kinase that becomes phosphorylated during muscle contraction.
Archives of biochemistry and biophysics 2002;397(2):224-31.
2001: Hannigan M O; Zhan L; Ai Y; Kotlyarov A; Gaestel M; Huang C K
Abnormal migration phenotype of mitogen-activated protein kinase-activated protein kinase 2-/- neutrophils in Zigmond chambers containing formyl-methionyl-leucyl-phenylalanine gradients.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):3953-61.
2001: Neininger A; Thielemann H; Gaestel M
FRET-based detection of different conformations of MK2.
EMBO reports 2001;2(8):703-8.
2001: Kontoyiannis D; Kotlyarov A; Carballo E; Alexopoulou L; Blackshear P J; Gaestel M; Davis R; Flavell R; Kollias G
Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology.
The EMBO journal 2001;20(14):3760-70.
2001: Butt E; Immler D; Meyer H E; Kotlyarov A; Laass K; Gaestel M
Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants.
The Journal of biological chemistry 2001;276(10):7108-13.
2000: Ehrnsperger M; Gaestel M; Buchner J
Analysis of chaperone properties of small Hsp's.
Methods in molecular biology (Clifton, N.J.) 2000;99():421-9.
1999: Kovarik P; Stoiber D; Eyers P A; Menghini R; Neininger A; Gaestel M; Cohen P; Decker T
Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13956-61.
1999: Winzen R; Kracht M; Ritter B; Wilhelm A; Chen C Y; Shyu A B; Müller M; Gaestel M; Resch K; Holtmann H
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.
The EMBO journal 1999;18(18):4969-80.
1999: Gross S; Knebel A; Tenev T; Neininger A; Gaestel M; Herrlich P; Böhmer F D
Inactivation of protein-tyrosine phosphatases as mechanism of UV-induced signal transduction.
The Journal of biological chemistry 1999;274(37):26378-86.
1999: Rolli M; Kotlyarov A; Sakamoto K M; Gaestel M; Neininger A
Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner.
The Journal of biological chemistry 1999;274(28):19559-64.
1999: Rogalla T; Ehrnsperger M; Preville X; Kotlyarov A; Lutsch G; Ducasse C; Paul C; Wieske M; Arrigo A P; Buchner J; Gaestel M
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation.
The Journal of biological chemistry 1999;274(27):18947-56.
1999: Ehrnsperger M; Lilie H; Gaestel M; Buchner J
The dynamics of Hsp25 quaternary structure. Structure and function of different oligomeric species.
The Journal of biological chemistry 1999;274(21):14867-74.
1999: Heidenreich O; Neininger A; Schratt G; Zinck R; Cahill M A; Engel K; Kotlyarov A; Kraft R; Kostka S; Gaestel M; Nordheim A
MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo.
The Journal of biological chemistry 1999;274(20):14434-43.
1998: Neininger A; Gaestel M
Evidence for a hsp25-specific mechanism involved in transcriptional activation by heat shock.
Experimental cell research 1998;242(1):285-93.
1998: Engel K; Kotlyarov A; Gaestel M
Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation.
The EMBO journal 1998;17(12):3363-71.
1998: Buchner J; Ehrnsperger M; Gaestel M; Walke S
Purification and characterization of small heat shock proteins.
Methods in enzymology 1998;290():339-49.
1997: Schultz H; Rogalla T; Engel K; Lee J C; Gaestel M
The protein kinase inhibitor SB203580 uncouples PMA-induced differentiation of HL-60 cells from phosphorylation of Hsp27.
Cell stress & chaperones 1997;2(1):41-9.
1997: Ehrnsperger M; Gräber S; Gaestel M; Buchner J
Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation.
The EMBO journal 1997;16(2):221-9.
1996: Gotthardt R; Neininger A; Gaestel M
The anti-cancer drug cisplatin induces H25 in Ehrlich ascites tumor cells by a mechanism different from transcriptional stimulation influencing predominantly H25 translation.
International journal of cancer. Journal international du cancer 1996;66(6):790-5.
1995: Engel K; Schultz H; Martin F; Kotlyarov A; Plath K; Hahn M; Heinemann U; Gaestel M
Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif.
The Journal of biological chemistry 1995;270(45):27213-21.
1995: Carver J A; Esposito G; Schwedersky G; Gaestel M
1H NMR spectroscopy reveals that mouse Hsp25 has a flexible C-terminal extension of 18 amino acids.
FEBS letters 1995;369(2-3):305-10.
1995: Engel K; Ahlers A; Brach M A; Herrmann F; Gaestel M
MAPKAP kinase 2 is activated by heat shock and TNF-alpha: in vivo phosphorylation of small heat shock protein results from stimulation of the MAP kinase cascade.
Journal of cellular biochemistry 1995;57(2):321-30.
1994: Ahlers A; Belka C; Gaestel M; Lamping N; Sott C; Herrmann F; Brach M A
Interleukin-1-induced intracellular signaling pathways converge in the activation of mitogen-activated protein kinase and mitogen-activated protein kinase-activated protein kinase 2 and the subsequent phosphorylation of the 27-kilodalton heat shock protein in monocytic cells.
Molecular pharmacology 1994;46(6):1077-83.
1994: van den IJssel P R; Overkamp P; Knauf U; Gaestel M; de Jong W W
Alpha A-crystallin confers cellular thermoresistance.
FEBS letters 1994;355(1):54-6.
1994: Plath K; Engel K; Schwedersky G; Gaestel M
Characterization of the proline-rich region of mouse MAPKAP kinase 2: influence on catalytic properties and binding to the c-abl SH3 domain in vitro.
Biochemical and biophysical research communications 1994;203(2):1188-94.
1994: Knauf U; Jakob U; Engel K; Buchner J; Gaestel M
Stress- and mitogen-induced phosphorylation of the small heat shock protein Hsp25 by MAPKAP kinase 2 is not essential for chaperone properties and cellular thermoresistance.
The EMBO journal 1994;13(1):54-60.
1993: Engel K; Plath K; Gaestel M
The MAP kinase-activated protein kinase 2 contains a proline-rich SH3-binding domain.
FEBS letters 1993;336(1):143-7.
1993: Merck K B; Horwitz J; Kersten M; Overkamp P; Gaestel M; Bloemendal H; de Jong W W
Comparison of the homologous carboxy-terminal domain and tail of alpha-crystallin and small heat shock protein.
Molecular biology reports 1993;18(3):209-15.
1993: Gaestel M; Gotthardt R; Müller T
Structure and organisation of a murine gene encoding small heat-shock protein Hsp25.
Gene 1993;128(2):279-83.
1993: Jakob U; Gaestel M; Engel K; Buchner J
Small heat shock proteins are molecular chaperones.
The Journal of biological chemistry 1993;268(3):1517-20.
1993: Gernold M; Knauf U; Gaestel M; Stahl J; Kloetzel P M
Development and tissue-specific distribution of mouse small heat shock protein hsp25.
Developmental genetics 1993;14(2):103-11.
1992: Gaestel M; Benndorf R; Hayess K; Priemer E; Engel K
Dephosphorylation of the small heat shock protein hsp25 by calcium/calmodulin-dependent (type 2B) protein phosphatase.
The Journal of biological chemistry 1992;267(30):21607-11.
1992: Knauf U; Bielka H; Gaestel M
Over-expression of the small heat-shock protein, hsp25, inhibits growth of Ehrlich ascites tumor cells.
FEBS letters 1992;309(3):297-302.
1991: Behlke J; Lutsch G; Gaestel M; Bielka H
Supramolecular structure of the recombinant murine small heat shock protein hsp25.
FEBS letters 1991;288(1-2):119-22.
1991: Gaestel M; Schröder W; Benndorf R; Lippmann C; Buchner K; Hucho F; Erdmann V A; Bielka H
Identification of the phosphorylation sites of the murine small heat shock protein hsp25.
The Journal of biological chemistry 1991;266(22):14721-4.
1991: Engel K; Knauf U; Gaestel M
Generation of antibodies against human hsp27 and murine hsp25 by immunization with a chimeric small heat shock protein.
Biomedica biochimica acta 1991;50(9):1065-71.
1991: Böhm H; Gross B; Gaestel M; Bommer U A; Ryffel G; Bielka H
The 5'-untranslated region of p23 mRNA from the Ehrlich ascites tumor is involved in translation control of the growth related protein p23.
Biomedica biochimica acta 1991;50(12):1193-203.
1989: Gross B; Gaestel M; Böhm H; Bielka H
cDNA sequence coding for a translationally controlled human tumor protein.
Nucleic acids research 1989;17(20):8367.
1989: Böhm H; Benndorf R; Gaestel M; Gross B; Nürnberg P; Kraft R; Otto A; Bielka H
The growth-related protein P23 of the Ehrlich ascites tumor: translational control, cloning and primary structure.
Biochemistry international 1989;19(2):277-86.
1989: Schunck W H; Kärgel E; Gross B; Wiedmann B; Mauersberger S; Köpke K; Kiessling U; Strauss M; Gaestel M; Müller H G
Molecular cloning and characterization of the primary structure of the alkane hydroxylating cytochrome P-450 from the yeast Candida maltosa.
Biochemical and biophysical research communications 1989;161(2):843-50.
1989: Gaestel M; Gross B; Benndorf R; Strauss M; Schunk W H; Kraft R; Otto A; Böhm H; Stahl J; Drabsch H
Molecular cloning, sequencing and expression in Escherichia coli of the 25-kDa growth-related protein of Ehrlich ascites tumor and its homology to mammalian stress proteins.
European journal of biochemistry / FEBS 1989;179(1):209-13.
1989: Noll F; Handschack W; Eichmann E; Gaestel M; Schneider F; Kuhl R; Löster K
Production and characterization of four monoclonal antibodies specific for human interferon-alpha-1 and -alpha-2.
Biomedica biochimica acta 1989;48(1):165-76.
1987: Karawajew L; Micheel B; Behrsing O; Gaestel M
Bispecific antibody-producing hybrid hybridomas selected by a fluorescence activated cell sorter.
Journal of immunological methods 1987;96(2):265-70.
1987: Karawajew L; Micheel B; Behrsing O; Gaestel M; Pasternak G
Use of fluorescence-activated cell sorting to select hybrid hybridomas producing bispecific monoclonal antibodies.
Haematology and blood transfusion 1987;31():367-8.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Matthias Gaestel

Research Profile (preview)

Chemicals & Drugs

Living Beings

Phenomena

Physiology

Concepts & Ideas

Genes & Molecular Sequences

Anatomy

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Matthias Gaestel (preview)

All Publications