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Guro Gafvelin

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J Grundström; I Janczewska; L Linton; Sarah Thunberg; Marianne van Hage; R Befrits; H Forsslund; Guro Gafvelin; M Eberhardson
Altered immunoregulatory profile during anti-tumour necrosis factor treatment of patients with inflammatory bowel disease.
Susanna L Lundström; Sarah Thunberg; Marianne van Hage; Anders Eklund; Guro Gafvelin; Reidar Grönneberg; Johan Grunewald; Jesper Z Haeggström; Bruce D Hammock; Henrik J Källberg; Jun Yang; Asa M Wheelock; Craig E Wheelock
Allergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocation.
Jeanette Grundström; Cecilia Kemi; Theresa Neimert-Andersson; Ola B Nilsson; Tiiu Saarne; Marianne van Hage; Mats Andersson; Guro Gafvelin
Covalent coupling of vitamin D3 to the major cat allergen Fel d 1 improves the effects of allergen-specific immunotherapy in a mouse model for cat allergy.

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All Publications

2012: J Grundström; I Janczewska; L Linton; Sarah Thunberg; Marianne van Hage; R Befrits; H Forsslund; Guro Gafvelin; M Eberhardson
Altered immunoregulatory profile during anti-tumour necrosis factor treatment of patients with inflammatory bowel disease.
Clinical and experimental immunology 2012;169(2):137-47.
2012: Susanna L Lundström; Sarah Thunberg; Marianne van Hage; Anders Eklund; Guro Gafvelin; Reidar Grönneberg; Johan Grunewald; Jesper Z Haeggström; Bruce D Hammock; Henrik J Källberg; Jun Yang; Asa M Wheelock; Craig E Wheelock
Allergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocation.
PloS one 2012;7(3):e33780.
2012: Jeanette Grundström; Cecilia Kemi; Theresa Neimert-Andersson; Ola B Nilsson; Tiiu Saarne; Marianne van Hage; Mats Andersson; Guro Gafvelin
Covalent coupling of vitamin D3 to the major cat allergen Fel d 1 improves the effects of allergen-specific immunotherapy in a mouse model for cat allergy.
International archives of allergy and immunology 2012;157(2):136-46.
2011: Theresa Neimert-Andersson; Julie Nilsen-Nygaard; Marianne van Hage; Louise Zettergren; Mats Andersson; Kurt Ingar Draget; Guro Gafvelin; Anne-Charlotte Hällgren; Joakim Langebäck; Alf Lindberg; Hans Grönlund
Improved immune responses in mice using the novel chitosan adjuvant ViscoGel, with a Haemophilus influenzae type b glycoconjugate vaccine.
Vaccine 2011;29(48):8965-73.
2011: T Saarne; T Neimert-Andersson; Hans Grönlund; M Jutel; Guro Gafvelin; Marianne van Hage
Treatment with a Fel d 1 hypoallergen reduces allergic responses in a mouse model for cat allergy.
Allergy 2011;66(2):255-63.
2011: Camilla Osterlund; Hans Grönlund; Guro Gafvelin; Anders Bucht
Non-proteolytic aeroallergens from mites, cat and dog exert adjuvant-like activation of bronchial epithelial cells.
International archives of allergy and immunology 2011;155(2):111-8.
2010: Hans Grönlund; Guro Gafvelin
Recombinant Bet v 1 vaccine for treatment of allergy to birch pollen.
Human vaccines 2010;6(12):970-7.
2010: Sarah Thunberg; Guro Gafvelin; M Nord; Reidar Grönneberg; Johan Grunewald; Anders Eklund; Marianne van Hage
Allergen provocation increases TH2-cytokines and FOXP3 expression in the asthmatic lung.
Allergy 2010;65(3):311-8.
2010: Hans Grönlund; Tiiu Saarne; Guro Gafvelin; Marianne van Hage
The major cat allergen, Fel d 1, in diagnosis and therapy.
International archives of allergy and immunology 2010;151(4):265-74.
2009: Sarah Thunberg; T Neimert-Andersson; Q Cheng; F Wermeling; Ulrika Bergström; L Swedin; S-E Dahlén; Elias Arnér; Annika Scheynius; M C I Karlsson; Guro Gafvelin; Marianne van Hage; Hans Grönlund
Prolonged antigen-exposure with carbohydrate particle based vaccination prevents allergic immune responses in sensitized mice.
Allergy 2009;64(6):919-26.
2008: Marianne van Hage; Hans Grönlund; Guro Gafvelin
[Biological engineering for new asthma therapy].
Läkartidningen 2008;105(26-27):1942-5.
2008: T Neimert-Andersson; Sarah Thunberg; L Swedin; Ursula Wiedermann; Gunilla Jacobsson Ekman; S-E Dahlén; Annika Scheynius; Hans Grönlund; Marianne van Hage; Guro Gafvelin
Carbohydrate-based particles reduce allergic inflammation in a mouse model for cat allergy.
Allergy 2008;63(5):518-26.
2008: Tanja Cirkovic Velickovic; Sarah Thunberg; Natalija Polovic; Theresa Neimert-Andersson; Hans Grönlund; Marianne van Hage; Guro Gafvelin
Low levels of endotoxin enhance allergen-stimulated proliferation and reduce the threshold for activation in human peripheral blood cells.
International archives of allergy and immunology 2008;146(1):1-10.
2007: Sarah Thunberg; Mübeccel Akdis; Cezmi A. Akdis; Reidar Grönneberg; Vivianne Malmström; Christina Trollmo; Marianne van Hage; Guro Gafvelin
Immune regulation by CD4+CD25+ T cells and interleukin-10 in birch pollen-allergic patients and non-allergic controls.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(8):1127-36.
2007: Liselotte Kaiser; Tanja Cirkovic Velickovic; Daniel Badia-Martinez; Justus Adedoyin; Sarah Thunberg; Dan Hallén; Kurt Berndt; Hans Grönlund; Guro Gafvelin; Marianne van Hage; Adnane Achour
Structural characterization of the tetrameric form of the major cat allergen Fel d 1.
Journal of molecular biology 2007;370(4):714-27.
2007: Guro Gafvelin; Stephen Parmley; Theresa Neimert-Andersson; Ulrich Blank; Tove L J Eriksson; Marianne van Hage; Juha Punnonen
Hypoallergens for allergen-specific immunotherapy by directed molecular evolution of mite group 2 allergens.
The Journal of biological chemistry 2007;282(6):3778-87.
2005: Linda Johansson; Guro Gafvelin; Elias Arnér
Selenocysteine in proteins-properties and biotechnological use.
Biochimica et biophysica acta 2005;1726(1):1-13.
2005: Guro Gafvelin; Sarah Thunberg; Marianne Kronqvist; Hans Grönlund; Reidar Grönneberg; Marita Troye-Blomberg; Mübeccel Akdis; Helmut Fiebig; Ashok Purohit; Friedrich Horak; Jürgen Reisinger; Verena Niederberger; Cezmi A. Akdis; Oliver Cromwell; Gabrielle Pauli; Rudolf Valenta; Marianne van Hage
Cytokine and antibody responses in birch-pollen-allergic patients treated with genetically modified derivatives of the major birch pollen allergen Bet v 1.
International archives of allergy and immunology 2005;138(1):59-66.
2005: Linda Johansson; Linda Svensson; Ulrika Bergström; Gunilla Jacobsson Ekman; Elias Arnér; Marianne van Hage; Anders Bucht; Guro Gafvelin
A mouse model for in vivo tracking of the major dust mite allergen Der p 2 after inhalation.
The FEBS journal 2005;272(13):3449-60.
2005: T Saarne; Liselotte Kaiser; Hans Grönlund; Omid Rasool; Guro Gafvelin; Marianne Van Hage-Hamsten
Rational design of hypoallergens applied to the major cat allergen Fel d 1.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(5):657-63.
2004: Verena Niederberger; Friedrich Horak; Susanne Vrtala; Susanne Spitzauer; Maria-Theresa Krauth; Peter Valent; Jürgen Reisinger; Martina Pelzmann; Brigitte Hayek; Marianne Kronqvist; Guro Gafvelin; Hans Grönlund; Ashok Purohit; Roland Suck; Helmut Fiebig; Oliver Cromwell; Gabrielle Pauli; Marianne Van Hage-Hamsten; Rudolf Valenta
Vaccination with genetically engineered allergens prevents progression of allergic disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101 Suppl 2():14677-82.
2004: Linda Johansson; Chunying Chen; Jan-Olov Thorell; Anna Fredriksson; Sharon Stone-Elander; Guro Gafvelin; Elias Arnér
Exploiting the 21st amino acid-purifying and labeling proteins by selenolate targeting.
Nature methods 2004;1(1):61-6.
2004: Theresa N Andersson; G Jacobsson Ekman; Hans Grönlund; Eva Buentke; Tove L J Eriksson; Annika Scheynius; Marianne Van Hage-Hamsten; Guro Gafvelin
A novel adjuvant-allergen complex, CBP-rFel d 1, induces up-regulation of CD86 expression and enhances cytokine release by human dendritic cells in vitro.
Immunology 2004;113(2):253-9.
2003: Tiiu Saarne; Liselotte Kaiser; Omid Rasool; Sonia Huecas; Marianne Van Hage-Hamsten; Guro Gafvelin
Cloning and characterisation of two IgE-binding proteins, homologous to tropomyosin and alpha-tubulin, from the mite Lepidoglyphus destructor.
International archives of allergy and immunology 2003;130(4):258-65.
2003: Liselotte Kaiser; Guro Gafvelin; Eva Johansson; Marianne Van Hage-Hamsten; Omid Rasool
Lep d 2 polymorphisms in wild and cultured Lepidoglyphus destructor mites.
European journal of biochemistry / FEBS 2003;270(4):646-53.
2001: Tove L J Eriksson; Guro Gafvelin; L H M Elfman; Catharina Johansson; Marianne Van Hage-Hamsten; S Olsson
T cell responses to recombinant isoforms, synthetic peptides and a mutant variant of Lep d 2, a major allergen from the dust mite Lepidoglyphus destructor.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(12):1881-90.
2001: Marianne Kronqvist; Eva Johansson; P Whitley; S Olsson; Guro Gafvelin; Annika Scheynius; Marianne Van Hage-Hamsten
A hypoallergenic derivative of the major allergen of the dust mite Lepidoglyphus destructor, Lep d 2.6Cys, induces less IgE reactivity and cellular response in the skin than recombinant Lep d 2.
International archives of allergy and immunology 2001;126(1):41-9.
2001: Alisa M Smith; DC Benjamin; N Hozic; Urszula Derewenda; W A Smith; W R Thomas; Guro Gafvelin; Marianne Van Hage-Hamsten; Martin D Chapman
The molecular basis of antigenic cross-reactivity between the group 2 mite allergens.
The Journal of allergy and clinical immunology 2001;107(6):977-84.
2001: Guro Gafvelin; Eva Johansson; A Lundin; Alisa M Smith; Martin D Chapman; DC Benjamin; Urszula Derewenda; Marianne Van Hage-Hamsten
Cross-reactivity studies of a new group 2 allergen from the dust mite Glycyphagus domesticus, Gly d 2, and group 2 allergens from Dermatophagoides pteronyssinus, Lepidoglyphus destructor, and Tyrophagus putrescentiae with recombinant allergens.
The Journal of allergy and clinical immunology 2001;107(3):511-8.
2001: Tove L J Eriksson; Omid Rasool; Sonia Huecas; P Whitley; Reto Crameri; Ulrich Appenzeller; Guro Gafvelin; Marianne Van Hage-Hamsten
Cloning of three new allergens from the dust mite Lepidoglyphus destructor using phage surface display technology.
European journal of biochemistry / FEBS 2001;268(2):287-94.
2000: Marianne Kronqvist; Eva Johansson; C G Magnusson; S Olsson; Tove L J Eriksson; Guro Gafvelin; Marianne Van Hage-Hamsten
Skin prick test and serological analysis with recombinant group 2 allergens of the dust mites L. destructor and T. putrescentiae.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(5):670-6.
1999: Eva Johansson; Tove L J Eriksson; S Olsson; Marianne Kronqvist; P Whitley; SG Johansson; Guro Gafvelin; Marianne Van Hage-Hamsten
Evaluation of specific IgE to the recombinant group 2 mite allergens Lep d 2 and Tyr p 2 in the Pharmacia CAP system.
International archives of allergy and immunology 1999;120(1):43-9.
1999: Tove L J Eriksson; P Whitley; Eva Johansson; Marianne Van Hage-Hamsten; Guro Gafvelin
Identification and characterisation of two allergens from the dust mite Acarus siro, homologous with fatty acid-binding proteins.
International archives of allergy and immunology 1999;119(4):275-81.
1999: Magnus Monné; Guro Gafvelin; R Nilsson; Gunnar von Heijne
N-tail translocation in a eukaryotic polytopic membrane protein: synergy between neighboring transmembrane segments.
European journal of biochemistry / FEBS 1999;263(1):264-9.
1998: IngMarie Nilsson; A Sääf; P Whitley; Guro Gafvelin; C Waller; Gunnar von Heijne
Proline-induced disruption of a transmembrane alpha-helix in its natural environment.
Journal of molecular biology 1998;284(4):1165-75.
1998: S Olsson; Marianne Van Hage-Hamsten; P Whitley; Eva Johansson; D R Hoffman; Guro Gafvelin; M Schmidt
Expression of two isoforms of Lep d 2, the major allergen of Lepidoglyphus destructor, in both prokaryotic and eukaryotic systems.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(8):984-91.
1997: Guro Gafvelin; M Sakaguchi; H Andersson; Gunnar von Heijne
Topological rules for membrane protein assembly in eukaryotic cells.
The Journal of biological chemistry 1997;272(10):6119-27.
1995: P Whitley; Guro Gafvelin; Gunnar von Heijne
SecA-independent translocation of the periplasmic N-terminal tail of an Escherichia coli inner membrane protein. Position-specific effects on translocation of positively charged residues and construction of a protein with a C-terminal translocation signal.
The Journal of biological chemistry 1995;270(50):29831-5.
1995: P Whitley; A Sääf; Guro Gafvelin; M Johansson; Ewa Wallin; Gunnar von Heijne
Membrane protein anchors and polytopic determinants.
Biochemical Society transactions 1995;23(4):965-7.
1995: A Sääf; H Andersson; Guro Gafvelin; Gunnar von Heijne
SecA-dependence of the translocation of a large periplasmic loop in the Escherichia coli MalF inner membrane protein is a function of sequence context.
Molecular membrane biology 1995;12(2):209-15.
1994: Guro Gafvelin; Gunnar von Heijne
Topological "frustration" in multispanning E. coli inner membrane proteins.
Cell 1994;77(3):401-12.