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Amos Gaikwad

Research Profile

Chemicals & Drugs

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Polymerase Chain Reaction

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Publications

TOP 3
Alfonso Quintás-Cardama; Ying Zhang; Zeev Estrov; Amos Gaikwad; David Harris; Hagop M Kantarjian; Taghi Manshouri; Srdan Verstovsek
Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor.
Carl E Allen; Liunan Li; Tricia L Peters; Hon-Chiu Eastwood Leung; Alexander Yu; Tsz-Kwong Man; Sivashankarappa Gurusiddappa; Michelle T Phillips; M John Hicks; Amos Gaikwad; Miriam Merad; Kenneth L McClain
Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells.
Amos Gaikwad; Cassia L Rye; Meenakshi Devidas; Nyla A Heerema; Andrew J Carroll; Shai Izraeli; Sharon E Plon; Giuseppe Basso; Andrea Pession; Karen Rabin
Prevalence and clinical correlates of JAK2 mutations in Down syndrome acute lymphoblastic leukaemia.

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All Publications

2011: Alfonso Quintás-Cardama; Ying Zhang; Zeev Estrov; Amos Gaikwad; David Harris; Hagop M Kantarjian; Taghi Manshouri; Srdan Verstovsek
Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor.
Investigational new drugs 2011;29(5):818-26.
2010: Carl E Allen; Liunan Li; Tricia L Peters; Hon-Chiu Eastwood Leung; Alexander Yu; Tsz-Kwong Man; Sivashankarappa Gurusiddappa; Michelle T Phillips; M John Hicks; Amos Gaikwad; Miriam Merad; Kenneth L McClain
Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(8):4557-67.
2009: Amos Gaikwad; Cassia L Rye; Meenakshi Devidas; Nyla A Heerema; Andrew J Carroll; Shai Izraeli; Sharon E Plon; Giuseppe Basso; Andrea Pession; Karen Rabin
Prevalence and clinical correlates of JAK2 mutations in Down syndrome acute lymphoblastic leukaemia.
British journal of haematology 2009;144(6):930-2.
2008: Chunlei Zhang; Baoqiang Li; Amos Gaikwad; Valsala Haridas; Zhixiang Xu; Jordan U Gutterman; Madeleine Duvic
Avicin D selectively induces apoptosis and downregulates p-STAT-3, bcl-2, and survivin in cutaneous T-cell lymphoma cells.
The Journal of investigative dermatology 2008;128(11):2728-35.
2007: Amos Gaikwad; Josef T Prchal
Study of two tyrosine kinase inhibitors on growth and signal transduction in polycythemia vera.
Experimental hematology 2007;35(11):1647-56.
2007: Zhi-Xiang Xu; Jiyong Liang; Valsala Haridas; Amos Gaikwad; F P Connolly; Gordon B Mills; Jordan U Gutterman
A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase.
Cell death and differentiation 2007;14(11):1948-57.
2007: Amos Gaikwad; Srdan Verstovsek; Donghoon Yoon; Ko-Tung Chang; Taghi Manshouri; Roberto H Nussenzveig; Jorge Cortes; William Vainchenker; Josef T Prchal
Imatinib effect on growth and signal transduction in polycythemia vera.
Experimental hematology 2007;35(6):931-8.
2007: Amos Gaikwad; Roberto H Nussenzveig; Enli Liu; Stephen Gottshalk; KoTung Chang; Josef T Prchal
In vitro expansion of erythroid progenitors from polycythemia vera patients leads to decrease in JAK2 V617F allele.
Experimental hematology 2007;35(4):587-95.
2007: Roberto H Nussenzveig; Sabina I Swierczek; Jaroslav Jelinek; Amos Gaikwad; Enli Liu; Srdan Verstovsek; Jaroslav F Prchal; Josef T Prchal
Polycythemia vera is not initiated by JAK2V617F mutation.
Experimental hematology 2007;35(1):32-8.
2006: Roberto H Nussenzveig; H Bindu Lingam; Amos Gaikwad; Qiqing Zhu; Naijie Jing; Josef T Prchal
A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia.
Haematologica 2006;91(11):1542-5.
2005: Jordan U Gutterman; Hong T Lai; Peirong Yang; Valsala Haridas; Amos Gaikwad; Stevan Marcus
Effects of the tumor inhibitory triterpenoid avicin G on cell integrity, cytokinesis, and protein ubiquitination in fission yeast.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(36):12771-6.
2005: Karim Iskander; Amos Gaikwad; Marilene Paquet; Delwin J Long; CORY BRAYTON; Roberto Barrios; Anil K Jaiswal
Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis.
Cancer research 2005;65(6):2054-8.
2005: Amos Gaikwad; Ann Poblenz; Valsala Haridas; Chunlei Zhang; Madeleine Duvic; Jordan U Gutterman
Triterpenoid electrophiles (avicins) suppress heat shock protein-70 and x-linked inhibitor of apoptosis proteins in malignant cells by activation of ubiquitin machinery: implications for proapoptotic activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(5):1953-62.
2004: Janet L Stringer; Amos Gaikwad; Bianca N Gonzales; Delwin J Long; Latoia M Marks; Anil K Jaiswal
Presence and induction of the enzyme NAD(P)H: quinone oxidoreductase 1 in the central nervous system.
The Journal of comparative neurology 2004;471(3):289-97.
2004: Valsala Haridas; Margaret Hanausek; Goshi Nishimura; Holly Soehnge; Amos Gaikwad; Maciej Narog; Erick Spears; Robert Zoltaszek; Zbigniew Walaszek; Jordan U Gutterman
Triterpenoid electrophiles (avicins) activate the innate stress response by redox regulation of a gene battery.
The Journal of clinical investigation 2004;113(1):65-73.
2002: Delwin J Long; Karim Iskander; Amos Gaikwad; Meral J Arin; Dennis R Roop; Richard Knox; Roberto Barrios; Anil K Jaiswal
Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity.
The Journal of biological chemistry 2002;277(48):46131-9.
2002: Delwin J Long; Amos Gaikwad; Asha Multani; Sen Pathak; Charles Montgomery; Frank J Gonzalez; Anil K Jaiswal
Disruption of the NAD(P)H:quinone oxidoreductase 1 (NQO1) gene in mice causes myelogenous hyperplasia.
Cancer research 2002;62(11):3030-6.
2001: Amos Gaikwad; Delwin J Long; Janet L Stringer; Anil K Jaiswal
In vivo role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in the regulation of intracellular redox state and accumulation of abdominal adipose tissue.
The Journal of biological chemistry 2001;276(25):22559-64.