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David Gailani

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Publications

TOP 3
Yipeng Geng; Anton Matafonov; James H Morrissey; Stephanie A Smith; Stephen B Smith; Mao-Fu Sun; Ingrid Verhamme; Qiufang Cheng; David Gailani
The dimeric structure of factor XI and zymogen activation.
Yipeng Geng; Amanda Messer; Stephen B Smith; Mao-Fu Sun; Ingrid Verhamme; S Paul Bajaj; David Gailani
A sequential mechanism for exosite-mediated factor IX activation by factor XIa.
Meghann Pine McManus; Christopher Frantz; David Gailani
Acquired factor XI deficiency in a child with membranoproliferative glomerulonephritis.

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All Publications

2013: Yipeng Geng; Anton Matafonov; James H Morrissey; Stephanie A Smith; Stephen B Smith; Mao-Fu Sun; Ingrid Verhamme; Qiufang Cheng; David Gailani
The dimeric structure of factor XI and zymogen activation.
Blood 2013;121(19):3962-9.
2012: Yipeng Geng; Amanda Messer; Stephen B Smith; Mao-Fu Sun; Ingrid Verhamme; S Paul Bajaj; David Gailani
A sequential mechanism for exosite-mediated factor IX activation by factor XIa.
The Journal of biological chemistry 2012;287(45):38200-9.
2012: Meghann Pine McManus; Christopher Frantz; David Gailani
Acquired factor XI deficiency in a child with membranoproliferative glomerulonephritis.
Pediatric blood & cancer 2012;59(1):173-5.
2012: Erik I Tucker; Norah G Verbout; David Gailani; Sawan Hurst; Philberta Y Leung; Owen J T McCarty; András Gruber
Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis.
Blood 2012;119(20):4762-8.
2010: Qiufang Cheng; Erik Tucker; Meghann S Pine; India Sisler; Anton Matafonov; Mao-Fu Sun; Tara C White-Adams; Ann Stephanie Smith; Stephen R Hanson; Owen J T McCarty; Thomas Renné; András Gruber; David Gailani
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.
Blood 2010;116(19):3981-9.
2010: David Gailani; Mao-Fu Sun; Qiufang Cheng; Anton Matafonov; Erik Tucker; Andras Gruber; Jonas Emsley
Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7.
Blood 2010;116(7):1185-6; author reply 1186-7.
2010: Tara White; Michelle Berny; I A Patel; Erik Tucker; David Gailani; Andras Gruber; Owen J T McCarty
Laminin promotes coagulation and thrombus formation in a factor XII-dependent manner.
Journal of thrombosis and haemostasis : JTH 2010;8(6):1295-301.
2009: David Gailani
Factor IX binding to collagen.
Journal of thrombosis and haemostasis : JTH 2009;7(11):1840-2.
2009: Tara White; Michelle Berny; Erik Tucker; Jacqueline Gertz; David Gailani; Rolf T Urbanus; Philip G de Groot; Andras Gruber; Owen J T McCarty
Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2).
Arteriosclerosis, thrombosis, and vascular biology 2009;29(10):1602-7.
2009: Dmitri V Kravtsov; Anton Matafonov; Erik Tucker; Mao-Fu Sun; Peter N Walsh; Andras Gruber; David Gailani
Factor XI contributes to thrombin generation in the absence of factor XII.
Blood 2009;114(2):452-8.
2009: David Gailani; S B Smith
Structural and functional features of factor XI.
Journal of thrombosis and haemostasis : JTH 2009;7 Suppl 1():75-8.
2009: Likui Yang; Mao-Fu Sun; David Gailani; Alireza R Rezaie
Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1-inhibitor.
Biochemistry 2009;48(7):1517-24.
2009: Erik Tucker; Ulla M Marzec; Tara White; Sawan Hurst; Sandra Rugonyi; Owen J T McCarty; David Gailani; Andras Gruber; Stephen R Hanson
Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI.
Blood 2009;113(4):936-44.
2008: Stephen B Smith; David Gailani
Update on the physiology and pathology of factor IX activation by factor XIa.
Expert review of hematology 2008;1(1):87-98.
2008: Erik Tucker; David Gailani; Sawan Hurst; Qiufang Cheng; Stephen R Hanson; Andras Gruber
Survival advantage of coagulation factor XI-deficient mice during peritoneal sepsis.
The Journal of infectious diseases 2008;198(2):271-4.
2008: Qiufang Cheng; Jeanelle Kantz; Greg Poffenberger; Alvin C Powers; David Gailani
Factor XI protein in human pancreas and kidney.
Thrombosis and haemostasis 2008;100(1):158-60.
2008: Stephen B Smith; Ingrid Verhamme; Mao-Fu Sun; Paul E Bock; David Gailani
Characterization of Novel Forms of Coagulation Factor XIa: independence of factor XIa subunits in factor IX activation.
The Journal of biological chemistry 2008;283(11):6696-705.
2008: Amy E Schmidt; Mao-Fu Sun; Taketoshi Ogawa; S Paul Bajaj; David Gailani
Functional role of residue 193 (chymotrypsin numbering) in serine proteases: influence of side chain length and beta-branching on the catalytic activity of blood coagulation factor XIa.
Biochemistry 2008;47(5):1326-35.
2007: David Gailani; Thomas Renné
Intrinsic pathway of coagulation and arterial thrombosis.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):2507-13.
2007: Patricia Anderson; David Gailani; Hendrik Feys; Weiqiang Gao; Elaine M Majerus; Karen Vanhoorelbeke; J Evan Sadler
Factor XI/ADAMTS13 complexes are quantitatively insignificant in human plasma.
Haematologica 2007;92(10):1419-22.
2007: Thomas Renné; David Gailani
Role of Factor XII in hemostasis and thrombosis: clinical implications.
Expert review of cardiovascular therapy 2007;5(4):733-41.
2007: David Gailani; Thomas Renné
The intrinsic pathway of coagulation: a target for treating thromboembolic disease?
Journal of thrombosis and haemostasis : JTH 2007;5(6):1106-12.
2007: David Gailani; A Schmidt; Mao-Fu Sun; P H Bolton-Maggs; S P Bajaj
A cross-reactive material positive variant of coagulation factor XI (FXIP520L) with a catalytic defect.
Journal of thrombosis and haemostasis : JTH 2007;5(4):781-7.
2006: Alireza R Rezaie; Mao-Fu Sun; David Gailani
Contributions of basic amino acids in the autolysis loop of factor XIa to serpin specificity.
Biochemistry 2006;45(31):9427-33.
2006: Brian S Donahue; David Gailani; A E Mast
Disposition of tissue factor pathway inhibitor during cardiopulmonary bypass.
Journal of thrombosis and haemostasis : JTH 2006;4(5):1011-6.
2006: Christoph Kleinschnitz; Guido Stoll; Martin Bendszus; Kai Schuh; Hans-Ulrich Pauer; Peter Burfeind; Christoph Renné; David Gailani; Bernhard Nieswandt; Thomas Renné
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis.
The Journal of experimental medicine 2006;203(3):513-8.
2006: Thomas Renné; Bernhard Nieswandt; David Gailani
The intrinsic pathway of coagulation is essential for thrombus stability in mice.
Blood cells, molecules & diseases 2006;36(2):148-51.
2005: Qiufang Cheng; Yong Zhao; William E Lawson; Vasiliy V Polosukhin; Joyce E Johnson; Timothy S Blackwell; David Gailani
The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice.
Blood 2005;106(9):3055-7.
2005: Thomas Renné; Miroslava Pozgajová; Sabine Grüner; Kai Schuh; Hans-Ulrich Pauer; Peter Burfeind; David Gailani; Bernhard Nieswandt
Defective thrombus formation in mice lacking coagulation factor XII.
The Journal of experimental medicine 2005;202(2):271-81.
2005: Taketoshi Ogawa; Ingrid Verhamme; Mao-Fu Sun; Paul E Bock; David Gailani
Exosite-mediated substrate recognition of factor IX by factor XIa. The factor XIa heavy chain is required for initial recognition of factor IX.
The Journal of biological chemistry 2005;280(25):23523-30.
2005: Dmitri V Kravtsov; Paul E Monahan; David Gailani
A classification system for cross-reactive material-negative factor XI deficiency.
Blood 2005;105(12):4671-3.
2004: Frank A Baglia; David Gailani; José A López; Peter N Walsh
Identification of a binding site for glycoprotein Ibalpha in the Apple 3 domain of factor XI.
The Journal of biological chemistry 2004;279(44):45470-6.
2004: Ariella Zivelin; T Ogawa; S Bulvik; meytal landau; John R Toomey; jacqueline lane; Uri Seligsohn; David Gailani
Severe factor XI deficiency caused by a Gly555 to Glu mutation (factor XI-Glu555): a cross-reactive material positive variant defective in factor IX activation.
Journal of thrombosis and haemostasis : JTH 2004;2(10):1782-9.
2004: David Gailani; Ariella Zivelin; D Sinha; Peter N Walsh
Do platelets synthesize factor XI?
Journal of thrombosis and haemostasis : JTH 2004;2(10):1709-12.
2004: Amy E Schmidt; Taketoshi Ogawa; David Gailani; S Paul Bajaj
Structural role of Gly(193) in serine proteases: investigations of a G555E (GLY193 in chymotrypsin) mutant of blood coagulation factor XI.
The Journal of biological chemistry 2004;279(28):29485-92.
2004: Dmitri V Kravtsov; Wenman Wu; Joost C M Meijers; Mao-Fu Sun; Morey A Blinder; Thao P Dang; Hongli Wang; David Gailani
Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain.
Blood 2004;104(1):128-34.
2003: Brian S Donahue; Daniel W Byrne; David Gailani; Alfred L George
Tissue factor and platelet glycoprotein Ib-alpha alleles are associated with age at first coronary bypass operation.
Anesthesiology 2003;99(6):1287-94.
2003: Qiufang Cheng; Mao-Fu Sun; Dmitri V Kravtsov; A Aktimur; David Gailani
Factor XI apple domains and protein dimerization.
Journal of thrombosis and haemostasis : JTH 2003;1(11):2340-7.
2003: Takashi Tarumi; Dmitri V Kravtsov; J H Moore; scott williams; David Gailani
Common single nucleotide polymorphisms in the promoter region of the human factor XI gene.
Journal of thrombosis and haemostasis : JTH 2003;1(8):1854-6.
2003: Aysar Aktimur; Melanie A Gabriel; David Gailani; John R Toomey
The factor IX gamma-carboxyglutamic acid (Gla) domain is involved in interactions between factor IX and factor XIa.
The Journal of biological chemistry 2003;278(10):7981-7.
2003: Brian S Donahue; David Gailani; Michael Scott Higgins; Davis C Drinkwater; Alfred L George
Factor V Leiden protects against blood loss and transfusion after cardiac surgery.
Circulation 2003;107(7):1003-8.
2002: Thomas Renné; Akiko Sugiyama; David Gailani; Willi Jahnen-Dechent; Ulrich Walter; Werner Müller-Esterl
Fine mapping of the H-kininogen binding site in plasma prekallikrein apple domain 2.
International immunopharmacology 2002;2(13-14):1867-73.
2002: Dipali Sinha; Mariola Marcinkiewicz; David Gailani; Peter N Walsh
Molecular cloning and biochemical characterization of rabbit factor XI.
The Biochemical journal 2002;367(Pt 1):49-56.
2002: Takashi Tarumi; Dmitri V Kravtsov; Mingming Zhao; scott williams; David Gailani
Cloning and characterization of the human factor XI gene promoter: transcription factor hepatocyte nuclear factor 4alpha (HNF-4alpha ) is required for hepatocyte-specific expression of factor XI.
The Journal of biological chemistry 2002;277(21):18510-6.
2002: Thomas Renné; David Gailani; Joost C M Meijers; Werner Müller-Esterl
Characterization of the H-kininogen-binding site on factor XI: a comparison of factor XI and plasma prekallikrein.
The Journal of biological chemistry 2002;277(7):4892-9.
2001: Mao-Fu Sun; Frank A Baglia; D Ho; Danko Martincic; R E Ware; Peter N Walsh; David Gailani
Defective binding of factor XI-N248 to activated human platelets.
Blood 2001;98(1):125-9.
2001: David Gailani; D Ho; Mao-Fu Sun; Qiufang Cheng; Peter N Walsh
Model for a factor IX activation complex on blood platelets: dimeric conformation of factor XIa is essential.
Blood 2001;97(10):3117-22.
2001: David Gailani
Gene targeting in hemostasis. factor XI.
Frontiers in bioscience : a journal and virtual library 2001;6():D201-7.
2000: Takashi Tarumi; Danko Martincic; James A Whitlock; Jonathan H Addy; scott williams; David Gailani
Conserved worldwide linkage disequilibrium in the human factor XI gene.
Genomics 2000;70(2):269-72.
2000: DH Ho; Karen O Badellino; Frank A Baglia; Mao-Fu Sun; M M Zhao; David Gailani; Peter N Walsh
The role of high molecular weight kininogen and prothrombin as cofactors in the binding of factor XI A3 domain to the platelet surface.
The Journal of biological chemistry 2000;275(33):25139-45.
2000: Takashi Tarumi; Danko Martincic; A Thomas; Robert Janco; M Hudson; P Baxter; David Gailani
Familial thrombophilia associated with fibrinogen paris V: Dusart syndrome.
Blood 2000;96(3):1191-3.
2000: David Gailani
Activation of factor IX by factor XIa.
Trends in cardiovascular medicine 2000;10(5):198-204.
1999: Mao-Fu Sun; Mingming Zhao; David Gailani
Identification of amino acids in the factor XI apple 3 domain required for activation of factor IX.
The Journal of biological chemistry 1999;274(51):36373-8.
1999: Danko Martincic; Vladimir Kravtsov; David Gailani
Factor XI messenger RNA in human platelets.
Blood 1999;94(10):3397-404.
1999: David Gailani; E P Reese
Anticoagulant-induced skin necrosis in a patient with hereditary deficiency of protein S.
American journal of hematology 1999;60(3):231-6.
1998: Mingming Zhao; T Abdel-Razek; Mao-Fu Sun; David Gailani
Characterization of a heparin binding site on the heavy chain of factor XI.
The Journal of biological chemistry 1998;273(47):31153-9.
1998: Danko Martincic; S A Zimmerman; R E Ware; Mao-Fu Sun; James A Whitlock; David Gailani
Identification of mutations and polymorphisms in the factor XI genes of an African American family by dideoxyfingerprinting.
Blood 1998;92(9):3309-17.
1997: David Gailani; Mao-Fu Sun; Y Sun
A comparison of murine and human factor XI.
Blood 1997;90(3):1055-64.
1997: David Gailani; Nina Lasky; George J Broze
A murine model of factor XI deficiency.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1997;8(2):134-44.
1996: Y Sun; David Gailani
Identification of a factor IX binding site on the third apple domain of activated factor XI.
The Journal of biological chemistry 1996;271(46):29023-8.
1994: T J Girard; David Gailani; George J Broze
Complementary DNA sequencing of canine tissue factor pathway inhibitor reveals a unique nanomeric repetitive sequence between the second and third Kunitz domains.
The Biochemical journal 1994;303 ( Pt 3)():923-8.
1994: David Gailani
Advances and dilemmas in factor XI.
Current opinion in hematology 1994;1(5):347-53.
1993: David Gailani; George J Broze
Factor XII-independent activation of factor XI in plasma: effects of sulfatides on tissue factor-induced coagulation.
Blood 1993;82(3):813-9.
1993: George J Broze; David Gailani
The role of factor XI in coagulation.
Thrombosis and haemostasis 1993;70(1):72-4.
1993: David Gailani; George J Broze
Effects of glycosaminoglycans on factor XI activation by thrombin.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1993;4(1):15-20.
1993: David Gailani; George J Broze
Factor XI activation by thrombin and factor XIa.
Seminars in thrombosis and hemostasis 1993;19(4):396-404.
1991: David Gailani; George J Broze
Factor XI activation in a revised model of blood coagulation.
Science (New York, N.Y.) 1991;253(5022):909-12.