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Valérie Gailus-Durner

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Limei Ju; Martin Klingenspor; Thomas Klopstock; Thure Adler; Martin Hrabě de Angelis; Lore Becker; Johannes Beckers; Renata Brandt; Dirk H Busch; Helmut Fuchs; Valérie Gailus-Durner; Wolfgang Hans; Marion Horsch; Ildikó Rácz; Birgit Rathkolb; Jan Rozman; Predrag Slijepcevic; Elaine Taylor; Gilbertus van der Horst; Jonathan Wing; Eckhard Wolf; Andreas Zimmer; Alan R Lehmann
SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities.
Tomáš Venit; Eckhard Wolf; Ali Önder Yildirim; Michal Kahle; Alžběta Kalendová; Birgit Rathkolb; Jana Rohožková; Thomas Rülicke; Volker Schmidt; Tobias Stoeger; Alexander Bohla; Martin Hrabě de Angelis; Rastislav Dzijak; Oliver Eickelberg; Helmut Fuchs; Valérie Gailus-Durner; Wolfgang Hans; Pavel Hozak
Mouse nuclear Myosin I knock-out shows interchangeability and redundancy of Myosin isoforms in the cell nucleus.
Oliver Puk; Sibylle Sabrautzki; Xiaohe Yan; Helmut Fuchs; Valérie Gailus-Durner; Martin Hrabe de Angelis; Jochen Graw
Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon.

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All Publications

2013: Limei Ju; Martin Klingenspor; Thomas Klopstock; Thure Adler; Martin Hrabě de Angelis; Lore Becker; Johannes Beckers; Renata Brandt; Dirk H Busch; Helmut Fuchs; Valérie Gailus-Durner; Wolfgang Hans; Marion Horsch; Ildikó Rácz; Birgit Rathkolb; Jan Rozman; Predrag Slijepcevic; Elaine Taylor; Gilbertus van der Horst; Jonathan Wing; Eckhard Wolf; Andreas Zimmer; Alan R Lehmann
SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities.
DNA repair 2013;12(5):356-66.
2013: Tomáš Venit; Eckhard Wolf; Ali Önder Yildirim; Michal Kahle; Alžběta Kalendová; Birgit Rathkolb; Jana Rohožková; Thomas Rülicke; Volker Schmidt; Tobias Stoeger; Alexander Bohla; Martin Hrabě de Angelis; Rastislav Dzijak; Oliver Eickelberg; Helmut Fuchs; Valérie Gailus-Durner; Wolfgang Hans; Pavel Hozak
Mouse nuclear Myosin I knock-out shows interchangeability and redundancy of Myosin isoforms in the cell nucleus.
PloS one 2013;8(4):e61406.
2013: Oliver Puk; Sibylle Sabrautzki; Xiaohe Yan; Helmut Fuchs; Valérie Gailus-Durner; Martin Hrabe de Angelis; Jochen Graw
Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon.
Molecular vision 2013;19():877-84.
2013: R Serpi; Julia Calzada-Wack; H Fuchs; Valérie Gailus-Durner; M Hrabrè de Angelis; T Klein-Rodewald; F Neff; M Poutanen; T Schuster; I Esposito
Inbred wild type mouse strains have distinct spontaneous morphological phenotypes.
Histology and histopathology 2013;28(1):79-88.
2012: Katrin Hochrath; Marion Horsch; Martin Klingenspor; Marcin Krawczyk; Monica Acalovschi; Johannes Beckers; Helmut Fuchs; Valérie Gailus-Durner; Reinhild Goebel; Miriam Langhirt; Kateryna Micklich; Birgit Rathkolb; Jan Rozman; Dietrich A Volmer; Eckhard Wolf; Martin Hrabe de Angelis; Frank Lammert
The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(12):5081-91.
2012: Robert Waltereit; Thomas Wieland; Karola Wittig; Wolfgang Wurst; Jerzy Adamski; Claire Bacon; Lore Becker; Stefan Berger; Julia Calzada-Wack; Martin Hrabe de Angelis; Volker Endris; Irene Esposito; Helmut Fuchs; Valérie Gailus-Durner; Lillian Garrett; Sabine M Hölter; Thomas Klopstock; Sergej Kutscherjawy; Uwe Leimer; Frauke Neff; Jutta Panke; Cornelia Prehn; Gudrun Rappold; Camie Schmitt; Miriam Schneider; Kai Schönig; Oliver von Bohlen und Halbach; Dusan Bartsch
Srgap3⁻/⁻ mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(11):4418-28.
2012: Frank Thiele; Wolfgang Wurst; Boris Ivandic; Hugo A Katus; Thomas S Lisse; Joan C Marini; Gerhard K H Przemeck; Catherine Reisenberg; Anja Schrewe; Johannes Beckers; Hollis Chaney; Christian M Cohrs; Armando Flor; Helmut Fuchs; Valérie Gailus-Durner; Wolfgang Hans; Marion Horsch; Martin Hrabé De Angelis
Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms.
Human molecular genetics 2012;21(16):3535-45.
2012: Helmut Fuchs; Valérie Gailus-Durner; Wolfgang Hans; Sabine M Hölter; Matthias Klaften; Martina Klempt; Martin Klingenspor; Thomas Klopstock; Birgit Rathkolb; Jan Rozman; Sibylle Sabrautzki; Ralf Schneider; Hartwig Seedorf; Eckhard Wolf; Wolfgang Wurst; Lore Becker; Ralf Elvert; Martin Hrabě de Angelis
Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines.
European journal of oral sciences 2012;120(4):269-77.
2012: Martin Irmler; Magdalena Kallnik; Martin Klingenspor; Helmut E Meyer; Jan Rozman; Holger Schulz; Fred W Van Leeuwen; Ines Bolle; Jing Jun Cheng; Frank J A Dennissen; Nicole Ehrhardt; Helmut Fuchs; Valérie Gailus-Durner; Romina J G Gentier; Denise J H P Hermes; Sabine M Hölter; David A Hopkins; Martin Hrabě de Angelis; Johannes Beckers
Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients.
Acta neuropathologica 2012;124(2):187-97.
2012: Benedetta Pozzi; Birgit Rathkolb; Simona Ronzoni; Anna Sciullo; Irina Treise; Eckhard Wolf; Thure Adler; Stefania Amodio; Christer Betsholtz; Ingrid Holmberg Betsholtz; Dirk H Busch; Stefano Casola; Daniela Castelletti; Martin Hrabě de Angelis; Pier Paolo Di Fiore; Helmut Fuchs; Valérie Gailus-Durner; Caterina Lucano; Nina Offenhäuser
The endocytic adaptor Eps15 controls marginal zone B cell numbers.
PloS one 2012;7(11):e50818.
2012: Ingeborg Klymiuk; Ralf Kühn; Nicole Leitner; Mathias Müller; Michaela Schlederer; Irina Treise; Barbara Fridrich; Auke Boersma; Dirk H Busch; Martin Hrabě de Angelis; Helmut Fuchs; Valérie Gailus-Durner; Martin Irmler; Lukas Kenner; Thure Adler; Johannes Beckers
In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis.
PloS one 2012;7(10):e44609.
2012: Giorgio Giacomo Galli; Wolfgang Hans; Kristian Honnens de Lichtenberg; Martin Hrabě de Angelis; Klaus Thorleif Jensen; Raffaele Adolfo Calogero; Matteo Carrara; John Robert Couchman; Les Coulton; Cathrine Kolster Fog; Helmut Fuchs; Valérie Gailus-Durner; Bettina Mentz; Hinke Arnolda Multhaupt; Juri Rappsilber; Andrea Vortkamp; Manuela Wuelling; Anders H Lund
Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone.
PLoS genetics 2012;8(5):e1002711.
2012: Pawel K Olszewski; Birgit Rathkolb; Ulf Risérus; Jan Rozman; Helgi B Schiöth; Siv Strömberg; Eckhard Wolf; Wolfgang Wurst; Martin Hrabě de Angelis; Johan Alsiö; Lore Becker; Nicole Ehrhardt; Ralf Elvert; Robert Fredriksson; Helmut Fuchs; Valérie Gailus-Durner; Wolfgang Hans; Sabine M Hölter; Josefin A Jacobsson; Martin Klingenspor; Anica Klockars; Thomas Klopstock; Allen S Levine; Claude Marcus; Manfred W Kilimann
Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans.
PLoS genetics 2012;8(3):e1002568.
2011: Juha Saarikangas; Pieta K Mattila; Markku Varjosalo; Miia Bovellan; Janne Hakanen; Julia Calzada-Wack; Monica Tost; Luise Jennen; Birgit Rathkolb; Wolfgang Hans; Marion Horsch; Mervi E Hyvönen; Nina Perälä; Helmut Fuchs; Valérie Gailus-Durner; Irene Esposito; Eckhard Wolf; Martin Hrabé De Angelis; Mikko J Frilander; Harri Savilahti; Hannu Sariola; Kirsi Sainio; Sanna Lehtonen; Jussi Taipale; Marjo Salminen; Pekka Lappalainen
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.
Journal of cell science 2011;124(Pt 8):1245-55.
2011: Alexander A Götz; Martin Hrabě de Angelis; Martin Klingenspor; Heiko G Rödel; Jan Rozman; Helmut Fuchs; Valérie Gailus-Durner; Tobias Stoeger
Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets.
Particle and fibre toxicology 2011;8():30.
2011: Monika Raab; Birgit Rathkolb; Jan Rozman; Nicole Sänger; Mourad Mohamed Sanhaji; Jost Seibler; Eckhard Wolf; Juping Yuan; Thure Adler; Martin Hrabě de Angelis; Martin Bergmann; Dirk H Busch; Julia Calzada-Wack; Irene Esposito; Helmut Fuchs; Valérie Gailus-Durner; Sven Kappel; Martin Klingenspor; Rainald Knecht; Andrea Krämer; Bertolt Kreft; Elisabeth Kurunci-Csacsko; Yves Matthess; Florian Prinz; Klaus Strebhardt
Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells.
Nature communications 2011;2():395.
2010: Jan M Deussing; Johannes Breu; Claudia Kühne; Magdalena Kallnik; Mirjam Bunck; Lisa Glasl; Yi-Chun Yen; Mathias V Schmidt; Regine Zurmühlen; Annette M Vogl; Valérie Gailus-Durner; Helmut Fuchs; Sabine M Hölter; Carsten T Wotjak; Rainer Landgraf; Martin Hrabé De Angelis; Florian Holsboer; Wolfgang Wurst
Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(27):9103-16.
2010: Elisabeth Kemter; Birgit Rathkolb; Lise Bankir; Anja Schrewe; Wolfgang Hans; Christina Landbrecht; Matthias Klaften; Boris Ivandic; Helmut Fuchs; Valérie Gailus-Durner; Martin Hrabé De Angelis; Eckhard Wolf; Rüdiger Wanke; Bernhard Aigner
Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia.
American journal of physiology. Renal physiology 2010;298(6):F1405-15.
2010: Christoph Kleinschnitz; Henrike Grund; Kirstin Wingler; Melanie E Armitage; Emma Jones; Manish Mittal; David Barit; Tobias Schwarz; Christian Geis; Peter Kraft; Konstanze Barthel; Michael K Schuhmann; Alexander M Herrmann; Sven G Meuth; Guido Stoll; Sabine Meurer; Anja Schrewe; Lore Becker; Valérie Gailus-Durner; Helmut Fuchs; Thomas Klopstock; Martin Hrabé De Angelis; Karin Jandeleit-Dahm; Ajay M Shah; Norbert Weissmann; Harald Schmidt
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.
PLoS biology 2010;8(9):.
2010: Arianna Tocchetti; Charlotte Blanche Ekalle Soppo; Fabio Zani; Fabrizio Bianchi; Maria Cristina Gagliani; Benedetta Pozzi; Jan Rozman; Ralf Elvert; Nicole Ehrhardt; Birgit Rathkolb; Corinna Moerth; Marion Horsch; Helmut Fuchs; Valérie Gailus-Durner; Johannes Beckers; Martin Klingenspor; Eckhard Wolf; Martin Hrabé de Angelis; Eugenio Scanziani; Carlo Tacchetti; Giorgio Scita; Pier Paolo Di Fiore; Nina Offenhäuser
Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice.
PloS one 2010;5(3):e9468.
2009: Elisabeth Kemter; Birgit Rathkolb; Jan Rozman; Wolfgang Hans; Anja Schrewe; Christina Landbrecht; Matthias Klaften; Boris Ivandic; Helmut Fuchs; Valérie Gailus-Durner; Martin Klingenspor; Martin Hrabé De Angelis; Eckhard Wolf; Rüdiger Wanke; Bernhard Aigner
Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism.
American journal of physiology. Renal physiology 2009;297(5):F1391-8.
2009: Birgit Rathkolb; Harry Noyes; Andrew Brass; Paul Dark; Helmut Fuchs; Valérie Gailus-Durner; John Gibson; Martin Hrabé De Angelis; Moses Ogugo; Fuad A Iraqi; Stephen J Kemp; Jan Naessens; Mathew E Pope; Eckhard Wolf; Morris Agaba
Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection.
Infection and immunity 2009;77(9):3948-57.
2009: Uwe Ahting; Thomas Floss; Nikolas Uez; Ilka Schneider-Lohmar; Lore Becker; Eva Kling; Arcangela Iuso; Andreas Bender; Martin Hrabé De Angelis; Valérie Gailus-Durner; Helmut Fuchs; Thomas Meitinger; Wolfgang Wurst; Holger Prokisch; Thomas Klopstock
Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import.
Biochimica et biophysica acta 2009;1787(5):371-6.
2009: Jörg Isensee; Luca Meoli; Valeria Zazzu; Christoph Nabzdyk; Henning Witt; Dian Soewarto; Karin Effertz; Helmut Fuchs; Valérie Gailus-Durner; Dirk Busch; Thure Adler; Martin Hrabé De Angelis; Markus Irgang; Christiane Otto; Patricia Ruiz Noppinger
Expression pattern of G protein-coupled receptor 30 in LacZ reporter mice.
Endocrinology 2009;150(4):1722-30.
2009: Isabel Rubio-Aliaga; Gerhard K H Przemeck; Helmut Fuchs; Valérie Gailus-Durner; Thure Adler; Wolfgang Hans; Marion Horsch; Birgit Rathkolb; Jan Rozman; Anja Schrewe; Sibylle Wagner; Sabine M Hoelter; Lore Becker; Thomas Klopstock; Wolfgang Wurst; Eckhard Wolf; Martin Klingenspor; Boris T Ivandic; Dirk H Busch; Johannes Beckers; Martin Hrabé De Angelis
Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes.
PloS one 2009;4(6):e6054.
2008: Holger Maier; Christoph Lengger; Bruno Simic; Helmut Fuchs; Valérie Gailus-Durner; Martin Hrabé De Angelis
MausDB: an open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects.
BMC bioinformatics 2008;9():169.
2007: Carola W Meyer; Ralf Elvert; André Scherag; Nicole Ehrhardt; Valérie Gailus-Durner; Helmut Fuchs; Helmut Schäfer; Martin Hrabé De Angelis; Gerhard Heldmaier; Martin Klingenspor
Power matters in closing the phenotyping gap.
Die Naturwissenschaften 2007;94(5):401-6.
2007: Franz Vauti; Tobias Goller; Rafael Beine; Lore Becker; Thomas Klopstock; Sabine M Hölter; Wolfgang Wurst; Helmut Fuchs; Valérie Gailus-Durner; Martin Hrabé De Angelis; Hans-Henning Arnold
The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour.
Gene 2007;389(2):174-85.
2006: Ilka Schneider; Werner S Tirsch; Theresa Faus-Kessler; Lore Becker; Eva Kling; Rose-Leah Austin Busse; Andreas Bender; Berend Feddersen; Johannes Tritschler; Helmut Fuchs; Valérie Gailus-Durner; Karl-Hans Englmeier; Martin Hrabé De Angelis; Thomas Klopstock
Systematic, standardized and comprehensive neurological phenotyping of inbred mice strains in the German Mouse Clinic.
Journal of neuroscience methods 2006;157(1):82-90.
2006: Ivan del Barco Barrantes; Ana Montero-Pedrazuela; Ana Guadaño-Ferraz; Maria Jesus Obregón; Raquel Martinez de Mena; Valérie Gailus-Durner; Helmut Fuchs; Tobias J Franz; Svetoslav Kalaydjiev; Martina Klempt; Sabine Hölter; Birgit Rathkolb; Claudia Reinhard; Gabriella Morreale de Escobar; Juan Bernal; Dirk H Busch; Wolfgang Wurst; Eckhard Wolf; Holger Schulz; Svetlana Shtrom; Erich Greiner; Martin Hrabé De Angelis; Heiner Westphal; Christof Niehrs
Generation and characterization of dickkopf3 mutant mice.
Molecular and cellular biology 2006;26(6):2317-26.
2005: Bastian Pasche; Svetoslav Kalaydjiev; Tobias J Franz; Elisabeth Kremmer; Valérie Gailus-Durner; Helmut Fuchs; Martin Hrabé De Angelis; Andreas Lengeling; Dirk H Busch
Sex-dependent susceptibility to Listeria monocytogenes infection is mediated by differential interleukin-10 production.
Infection and immunity 2005;73(9):5952-60.
2004: Claudia Dalke; Jana Löster; Helmut Fuchs; Valérie Gailus-Durner; Dian Soewarto; Jack Favor; Angelika Neuhäuser-Klaus; Walter Pretsch; Florian Gekeler; Kei Shinoda; Eberhart Zrenner; Thomas Meitinger; Martin Hrabé De Angelis; Jochen Graw
Electroretinography as a screening method for mutations causing retinal dysfunction in mice.
Investigative ophthalmology & visual science 2004;45(2):601-9.
2001: M Scherf; Andreas Klingenhoff; Kornelie Frech; K Quandt; Ralf Schneider; Korbinian Grote; Matthias Frisch; Valérie Gailus-Durner; A Seidel; Ruth Brack-Werner; Thomas Werner
First pass annotation of promoters on human chromosome 22.
Genome research 2001;11(3):333-40.
2001: Valérie Gailus-Durner; M Scherf; Thomas Werner
Experimental data of a single promoter can be used for in silico detection of genes with related regulation in the absence of sequence similarity.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(1):67-72.