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James Gainer

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James V Gainer; Michael Lipkowitz; Chang Yu; Michael R Waterman; Elliott P Dawson; Jorge H Capdevila; Nancy Brown
Association of a CYP4A11 variant and blood pressure in black men.
Cheryl L Laffer; James V Gainer; Michael R Waterman; Jorge H Capdevila; Michal Laniado-Schwartzman; Alberto Nasjletti; Nancy Brown; Fernando Elijovich
The T8590C polymorphism of CYP4A11 and 20-hydroxyeicosatetraenoic acid in essential hypertension.
Gary P Van Guilder; Mias Pretorius; James M Luther; James Brian Byrd; Kevin Hill; James V Gainer; Nancy Brown
Bradykinin type 2 receptor BE1 genotype influences bradykinin-dependent vasodilation during angiotensin-converting enzyme inhibition.

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All Publications

2008: James V Gainer; Michael Lipkowitz; Chang Yu; Michael R Waterman; Elliott P Dawson; Jorge H Capdevila; Nancy Brown
Association of a CYP4A11 variant and blood pressure in black men.
Journal of the American Society of Nephrology : JASN 2008;19(8):1606-12.
2008: Cheryl L Laffer; James V Gainer; Michael R Waterman; Jorge H Capdevila; Michal Laniado-Schwartzman; Alberto Nasjletti; Nancy Brown; Fernando Elijovich
The T8590C polymorphism of CYP4A11 and 20-hydroxyeicosatetraenoic acid in essential hypertension.
Hypertension 2008;51(3):767-72.
2008: Gary P Van Guilder; Mias Pretorius; James M Luther; James Brian Byrd; Kevin Hill; James V Gainer; Nancy Brown
Bradykinin type 2 receptor BE1 genotype influences bradykinin-dependent vasodilation during angiotensin-converting enzyme inhibition.
Hypertension 2008;51(2):454-9.
2008: James Brian Byrd; Karine Touzin; Saba Sile; James V Gainer; Chang Yu; John Nadeau; Albert Adam; Nancy Brown
Dipeptidyl peptidase IV in angiotensin-converting enzyme inhibitor associated angioedema.
Hypertension 2008;51(1):141-7.
2008: Mias Pretorius; James V Gainer; G P Van Guilder; E B Coelho; James M Luther; P Fong; D D Rosenbaum; Hector A Malave; Chang Yu; Marylyn Ritchie; Douglas E Vaughan; Nancy Brown
The bradykinin type 2 receptor BE1 polymorphism and ethnicity influence systolic blood pressure and vascular resistance.
Clinical pharmacology and therapeutics 2008;83(1):122-9.
2007: Saba Sile; Niloufar B Gillani; Digna R Velez; Carlos G Vanoye; Chang Yu; Loretta M Byrne; James V Gainer; Nancy Brown; scott williams; Alfred L George
Functional BSND variants in essential hypertension.
American journal of hypertension 2007;20(11):1176-1182.
2007: Dawood Darbar; Alison A Motsinger; Marylyn Ritchie; James V Gainer; Dan Mark Roden
Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(6):743-9.
2006: James M Luther; James V Gainer; Laine J Murphey; Chang Yu; Douglas E Vaughan; Jason D Morrow; Nancy Brown
Angiotensin II induces interleukin-6 in humans through a mineralocorticoid receptor-dependent mechanism.
Hypertension 2006;48(6):1050-7.
2006: Rocio Zamorano; Sunil Suchindran; James V Gainer
3'-Untranslated region of the type 2 bradykinin receptor is a potent regulator of gene expression.
American journal of physiology. Renal physiology 2006;290(2):F456-64.
2005: James V Gainer; Aouatef Bellamine; Elliott P Dawson; Kristie E Womble; Sarah W Grant; Yarong Wang; L Adrienne Cupples; Chao-Yu Guo; Serkalem Demissie; Christopher J O'Donnell; Nancy Brown; Michael R Waterman; Jorge H Capdevila
Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.
Circulation 2005;111(1):63-9.
2004: Marshall Summar; James V Gainer; Mias Pretorius; Hector A Malave; Stephanie Harris; Lynn D Hall; Alec D Weisberg; Douglas E Vaughan; Brian W Christman; Nancy Brown
Relationship between carbamoyl-phosphate synthetase genotype and systemic vascular function.
Hypertension 2004;43(2):186-91.
2003: Aouatef Bellamine; Yarong Wang; Michael R Waterman; James V Gainer; Elliott P Dawson; Nancy Brown; Jorge H Capdevila
Characterization of the CYP4A11 gene, a second CYP4A gene in humans.
Archives of biochemistry and biophysics 2003;409(1):221-7.
2002: David A Rosenbaum; Mias Pretorius; James V Gainer; Daniel Byrne; Laine J Murphey; Corrie A Painter; Douglas E Vaughan; Nancy Brown
Ethnicity affects vasodilation, but not endothelial tissue plasminogen activator release, in response to bradykinin.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):1023-8.
2001: T Wilsdorf; James V Gainer; Laine J Murphey; Douglas E Vaughan; Nancy Brown
Angiotensin-(1-7) does not affect vasodilator or TPA responses to bradykinin in human forearm.
Hypertension 2001;37(4):1136-40.
2000: James V Gainer; Nancy Brown; Magdalena Bachvarova; Luc Bastien; I Maltais; Francois Marceau; Dimcho Bachvarov
Altered frequency of a promoter polymorphism of the kinin B2 receptor gene in hypertensive African-Americans.
American journal of hypertension 2000;13(12):1268-73.
2000: Nancy Brown; James V Gainer; Laine J Murphey; Douglas E Vaughan
Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through B(2) receptor-dependent, NO synthase-independent, and cyclooxygenase-independent pathway.
Circulation 2000;102(18):2190-6.
2000: Laine J Murphey; James V Gainer; Douglas E Vaughan; Nancy Brown
Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin.
Circulation 2000;102(8):829-32.
2000: Hong-Guang Xie; C Michael Stein; Richard B Kim; James V Gainer; Gbenga G Sofowora; Victor Dishy; Nancy Brown; R E Goree; Jonathan L Haines; Alastair J J Wood
Human beta2-adrenergic receptor polymorphisms: no association with essential hypertension in black or white Americans.
Clinical pharmacology and therapeutics 2000;67(6):670-5.
1999: Hong-Guang Xie; Richard B Kim; C Michael Stein; James V Gainer; Nancy Brown; Alastair J J Wood
Alpha1A-adrenergic receptor polymorphism: association with ethnicity but not essential hypertension.
Pharmacogenetics 1999;9(5):651-6.
1999: Hong-Guang Xie; C Michael Stein; Richard B Kim; Zhou-Sheng Xiao; Nan He; Hong-Hao Zhou; James V Gainer; Nancy Brown; Jonathan L Haines; Alastair J J Wood
Frequency of functionally important beta-2 adrenoceptor polymorphisms varies markedly among African-American, Caucasian and Chinese individuals.
Pharmacogenetics 1999;9(4):511-6.
1999: Nancy Brown; James V Gainer; C Michael Stein; Douglas E Vaughan
Bradykinin stimulates tissue plasminogen activator release in human vasculature.
Hypertension 1999;33(6):1431-5.
1998: James V Gainer; Jason D Morrow; A Loveland; D J King; Nancy Brown
Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects.
The New England journal of medicine 1998;339(18):1285-92.
1998: S K Gandhi; James V Gainer; D King; Nancy Brown
Gender affects renal vasoconstrictor response to Ang I and Ang II.
Hypertension 1998;31(1):90-6.
1997: James V Gainer; Tracy E Hunley; Valentina Kon; J H Nadeau; James A S Muldowney; Nancy Brown
Angiotensin II type I receptor polymorphism in African Americans lower frequency of the C1166 variant.
Biochemistry and molecular biology international 1997;43(1):227-31.
1996: Nancy Brown; D Ryder; James V Gainer; Jason D Morrow; John Nadeau
Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin.
The Journal of pharmacology and experimental therapeutics 1996;279(2):703-12.
1996: James V Gainer; J H Nadeau; D Ryder; Nancy Brown
Increased sensitivity to bradykinin among African Americans.
The Journal of allergy and clinical immunology 1996;98(2):283-7.