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Sehamuddin Galadari

Research Profile

Chemicals & Drugs

Anatomy

Phenomena

Living Beings

Rats
Ranidae

Physiology

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Publications

TOP 3
Shahanas Chathoth; Alaa Galadari; Mahendra Patel; Faisal Thayyullathil; Sehamuddin Galadari
Purification and biochemical characterization of membrane-bound neutral ceramidase from camel brain (Camelus dromedarius).
Faisal Thayyullathil; Shahanas Chathoth; Jaleel Kizhakkayil; Siraj Pallichankandy; Mahendra Patel; Anees Rahman; Sehamuddin Galadari
Caspase-3 mediated release of SAC domain containing fragment from Par-4 is necessary for the sphingosine-induced apoptosis in Jurkat cells.
Oleg I Voitychuk; Ganna V Sotkis; Valentyna S Asmolkova; Sehamuddin Galadari; Nadiya M Gula; Frank C Howarth; Murat Oz; Yaroslav Shuba
Modulation of excitability, membrane currents and survival of cardiac myocytes by N-acylethanolamines.

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All Publications

2013: Shahanas Chathoth; Alaa Galadari; Mahendra Patel; Faisal Thayyullathil; Sehamuddin Galadari
Purification and biochemical characterization of membrane-bound neutral ceramidase from camel brain (Camelus dromedarius).
International journal of biochemistry and molecular biology 2013;4(1):54-66.
2013: Faisal Thayyullathil; Shahanas Chathoth; Jaleel Kizhakkayil; Siraj Pallichankandy; Mahendra Patel; Anees Rahman; Sehamuddin Galadari
Caspase-3 mediated release of SAC domain containing fragment from Par-4 is necessary for the sphingosine-induced apoptosis in Jurkat cells.
Journal of molecular signaling 2013;8(1):2.
2012: Oleg I Voitychuk; Ganna V Sotkis; Valentyna S Asmolkova; Sehamuddin Galadari; Nadiya M Gula; Frank C Howarth; Murat Oz; Yaroslav Shuba
Modulation of excitability, membrane currents and survival of cardiac myocytes by N-acylethanolamines.
Biochimica et biophysica acta 2012;1821(9):1167-76.
2012: Jaleel Kizhakkayil; Mahendra Patel; Faisal Thayyullathil; Shahanas Chathoth; Abdulkader Hago; Sehamuddin Galadari
Glutathione regulates caspase-dependent ceramide production and curcumin-induced apoptosis in human leukemic cells.
Free radical biology & medicine 2012;52(9):1854-64.
2011: Faisal Thayyullathil; Shahanas Chathoth; Alaa Galadari; Abdulkader Hago; Jaleel Kizhakkayil; Mahendra Patel; Sehamuddin Galadari
Glutathione selectively inhibits Doxorubicin induced phosphorylation of p53Ser¹⁵, caspase dependent ceramide production and apoptosis in human leukemic cells.
Biochemical and biophysical research communications 2011;411(1):1-6.
2011: Faisal Thayyullathil; Shahanas Chathoth; Allen Shahin; Jaleel Kizhakkayil; Abdulkader Hago; Mahendra Patel; Sehamuddin Galadari
Protein phosphatase 1-dependent dephosphorylation of Akt is the prime signaling event in sphingosine-induced apoptosis in Jurkat cells.
Journal of cellular biochemistry 2011;112(4):1138-53.
2011: Faisal Thayyullathil; Shahanas Chathoth; Abdulkader Hago; Mahendra Patel; Zdzislaw M Szulc; Yusuf Hannun; Sehamuddin Galadari
Purification and characterization of a second type of neutral ceramidase from rat brain: a second more hydrophobic form of rat brain ceramidase.
Biochimica et biophysica acta 2011;1811(4):242-52.
2010: K H S Yang; D Isaev; M Morales; G Petroianu; Sehamuddin Galadari; Murat Oz
The effect of Δ9-tetrahydrocannabinol on 5-HT3 receptors depends on the current density.
Neuroscience 2010;171(1):40-9.
2010: Keun-Hang Yang; Sehamuddin Galadari; Dmytro Isaev; Georg Petroianu; Toni S Shippenberg; Murat Oz
The nonpsychoactive cannabinoid cannabidiol inhibits 5-hydroxytryptamine3A receptor-mediated currents in Xenopus laevis oocytes.
The Journal of pharmacology and experimental therapeutics 2010;333(2):547-54.
2010: Jaleel Kizhakkayil; Faisal Thayyullathil; Shahanas Chathoth; Abdulkader Hago; Mahendra Patel; Sehamuddin Galadari
Modulation of curcumin-induced Akt phosphorylation and apoptosis by PI3K inhibitor in MCF-7 cells.
Biochemical and biophysical research communications 2010;394(3):476-81.
2010: Murat Oz; Vanaja Jaligam; Sehamuddin Galadari; George Petroianu; Yaroslav M Shuba; Toni S Shippenberg
The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism.
Journal of neurochemistry 2010;112(6):1454-64.
2009: Shahanas Chathoth; Faisal Thayyullathil; Abdulkader Hago; Allen Shahin; Mahendra Patel; Sehamuddin Galadari
UVC-induced apoptosis in Dubca cells is independent of JNK activation and p53(Ser-15) phosphorylation.
Biochemical and biophysical research communications 2009;383(4):426-32.
2009: Wei Sun; Wei Hu; Ruijuan Xu; Junfei Jin; Zdzislaw Szulc; Guofeng Zhang; Sehamuddin Galadari; Lina M Obeid; Cungui Mao
Alkaline ceramidase 2 regulates beta1 integrin maturation and cell adhesion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(2):656-66.
2008: Faisal Thayyullathil; Shahanas Chathoth; Abdulkader Hago; Mahendra Patel; Sehamuddin Galadari
Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells.
Free radical biology & medicine 2008;45(10):1403-12.
2008: Sehamuddin Galadari; Faisal Thayyullathil; Abdulkader Hago; Mahendra Patel; Shahanas Chathoth
Akt depletion is an important determinant of L929 cell death following heat stress.
Annals of the New York Academy of Sciences 2008;1138():385-92.
2008: Faisal Thayyullathil; Shahanas Chathoth; Abdulkader Hago; Ulli Wernery; Mahendra Patel; Sehamuddin Galadari
Investigation of heat stress response in the camel fibroblast cell line dubca.
Annals of the New York Academy of Sciences 2008;1138():376-84.
2008: J Michael Conlon; Sehamuddin Galadari; Haider Raza; Eric Condamine
Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7.
Chemical biology & drug design 2008;72(1):58-64.
2007: J Michael Conlon; Rokaya Al-Kharrge; Eman Ahmed; Haider Raza; Sehamuddin Galadari; Eric Condamine
Effect of aminoisobutyric acid (Aib) substitutions on the antimicrobial and cytolytic activities of the frog skin peptide, temporin-1DRa.
Peptides 2007;28(10):2075-80.
2006: S Salman Ashraf; Sehamuddin Galadari; Mahendra Patel
Protein S-thiolation and depletion of intracellular glutathione in skin fibroblasts exposed to various sources of oxidative stress.
Environmental toxicology and pharmacology 2006;22(1):75-9.
2006: Sehamuddin Galadari; Bill X Wu; Cungui Mao; Patrick Roddy; Samer El Bawab; Yusuf A Hannun
Identification of a novel amidase motif in neutral ceramidase.
The Biochemical journal 2006;393(Pt 3):687-95.
2005: J Michael Conlon; Bency Abraham; Sehamuddin Galadari; Floyd C Knoop; Agnes Sonnevend; Tibor Pál
Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives.
Peptides 2005;26(11):2104-10.
2005: Tibor Pál; Agnes Sonnevend; Sehamuddin Galadari; J Michael Conlon
Design of potent, non-toxic antimicrobial agents based upon the structure of the frog skin peptide, pseudin-2.
Regulatory peptides 2005;129(1-3):85-91.
2003: Cungui Mao; Ruijuan Xu; Zdzislaw Szulc; Jacek Bielawski; Kevin P Becker; Alicja Bielawska; Sehamuddin Galadari; Wei Hu; Lina M Obeid
Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramides.
The Journal of biological chemistry 2003;278(33):31184-91.
2001: Sehamuddin Galadari; A Hago; M Patel
Effects of cations on ceramide-activated protein phosphatase 2A.
Experimental & molecular medicine 2001;33(4):240-4.
2001: Charles E Chalfant; Besim Ogretmen; Sehamuddin Galadari; Bart-Jan Kroesen; Benjamin J Pettus; Yusuf A Hannun
FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1.
The Journal of biological chemistry 2001;276(48):44848-55.
2001: Cungui Mao; Ruijuan Xu; Zdzislaw Szulc; Alicja Bielawska; Sehamuddin Galadari; Lina M Obeid
Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide.
The Journal of biological chemistry 2001;276(28):26577-88.
2000: MS Nur-E-Kamal; MM Qureshi; MK Ijaz; Sehamuddin Galadari; Haider Raza
Proto-oncogene ras GTPase-linked induction of glutathione-S-transferase by growth factors in PC12 cells.
International journal of oncology 2000;16(5):1043-8.