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Haruhiko Aoyagi

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Genes & Molecular Sequences

Amino Acid Sequence

Phenomena

Circular Dichroism

Chemicals & Drugs

Concepts & Ideas

Anatomy

Lipid Bilayers

Procedures

Disorders

Hemolysis

Physiology

Transfection

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Co-Publications
Name
27
Niidome, Takuro
23
Lee, Sannamu
19
Hatakeyama, Tomomitsu
13
Hirayama, Toshiya
13
Wada, Akihiro
9
Ohmori, N
6
Yahiro, Kinnosuke
6
Kirino, Yutaka
5
Mihara, H
5
Kuwahara, Hiromiki
4
Sugawara, Hajime
4
Sugihara, Gohsuke
4
Moss, Joel
3
Ohsaki, Mio
3
Yamasaki, Nobuyuki

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Publications

TOP 3
Sugawara Hajime; Kusunoki Masami; Kurisu Genji; Fujimoto Tokiko; Aoyagi Haruhiko; Hatakeyama Tomomitsu
Characteristic recognition of N-acetylgalactosamine by an invertebrate C-type Lectin, CEL-I, revealed by X-ray crystallographic analysis.
Hatakeyama Tomomitsu; Shiba Kouhei; Matsuo Noriaki; Fujimoto Tokiko; Oda Tatsuya; Sugawara Hajime; Aoyagi Haruhiko
Characterization of recombinant CEL-I, a GalNAc-specific C-type lectin, expressed in Escherichia coli using an artificial synthetic gene.
Hatakeyama Tomomitsu; Suenaga Tomoko; Eto Seiichiro; Niidome Takuro; Aoyagi Haruhiko
Antibacterial activity of peptides derived from the C-terminal region of a hemolytic lectin, CEL-III, from the marine invertebrate Cucumaria echinata.

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All Publications

2004: Sugawara Hajime; Kusunoki Masami; Kurisu Genji; Fujimoto Tokiko; Aoyagi Haruhiko; Hatakeyama Tomomitsu
Characteristic recognition of N-acetylgalactosamine by an invertebrate C-type Lectin, CEL-I, revealed by X-ray crystallographic analysis.
The Journal of biological chemistry 2004;279(43):45219-25.
2004: Hatakeyama Tomomitsu; Shiba Kouhei; Matsuo Noriaki; Fujimoto Tokiko; Oda Tatsuya; Sugawara Hajime; Aoyagi Haruhiko
Characterization of recombinant CEL-I, a GalNAc-specific C-type lectin, expressed in Escherichia coli using an artificial synthetic gene.
Journal of biochemistry 2004;135(1):101-7.
2004: Hatakeyama Tomomitsu; Suenaga Tomoko; Eto Seiichiro; Niidome Takuro; Aoyagi Haruhiko
Antibacterial activity of peptides derived from the C-terminal region of a hemolytic lectin, CEL-III, from the marine invertebrate Cucumaria echinata.
Journal of biochemistry 2004;135(1):65-70.
2003: Yahiro Kinnosuke; Wada Akihiro; Nakayama Masaaki; Kimura Takahiro; Ogushi Ken-ichi; Niidome Takuro; Aoyagi Haruhiko; Yoshino Ken-ichi; Yonezawa Kazuyoshi; Moss Joel; Hirayama Toshiya
Protein-tyrosine phosphatase alpha, RPTP alpha, is a Helicobacter pylori VacA receptor.
The Journal of biological chemistry 2003;278(21):19183-9.
2003: Okuda Tatsuya; Kidoaki Satoru; Ohsaki Mio; Koyama Yoshiyuki; Yoshikawa Kenichi; Niidome Takuro; Aoyagi Haruhiko
Time-dependent complex formation of dendritic poly(L-lysine) with plasmid DNA and correlation with in vitro transfection efficiencies.
Organic & biomolecular chemistry 2003;1(8):1270-3.
2002: Ohsaki Mio; Okuda Tatsuya; Wada Akihiro; Hirayama Toshiya; Niidome Takuro; Aoyagi Haruhiko
In vitro gene transfection using dendritic poly(L-lysine).
Bioconjugate chemistry 2002;13(3):510-7.
2002: Kuwahara Hiromiki; Yamasaki Takayuki; Hatakeyama Tomomitsu; Aoyagi Haruhiko; Fujisawa Tetsuro
Oligomerization process of the hemolytic lectin CEL-III purified from a sea cucumber, Cucumaria echinata.
Journal of biochemistry 2002;131(5):751-6.
2002: Hatakeyama Tomomitsu; Matsuo Noriaki; Shiba Kouhei; Nishinohara Shoichi; Yamasaki Nobuyuki; Sugawara Hajime; Aoyagi Haruhiko
Amino acid sequence and carbohydrate-binding analysis of the N-acetyl-D-galactosamine-specific C-type lectin, CEL-I, from the Holothuroidea, Cucumaria echinata.
Bioscience, biotechnology, and biochemistry 2002;66(1):157-63.
2002: Hatakeyama Tomomitsu; Matsuo Noriaki; Aoyagi Haruhiko; Sugawara Hajime; Uchida Tatsuya; Kurisu Genji; Kusunoki Masami
Crystallization and preliminary crystallographic study of an invertebrate C-type lectin, CEL-I, from the marine invertebrate Cucumaria echinata.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 1):143-4.
2001: Ogushi K; Wada A; Niidome T; Mori N; Oishi K; Nagatake T; Takahashi A; Asakura H; Makino S; Hojo H; Nakahara Y; Ohsaki M; Hatakeyama T; Aoyagi H; Kurazono H; Moss J; Hirayama T
Salmonella enteritidis FliC (flagella filament protein) induces human beta-defensin-2 mRNA production by Caco-2 cells.
The Journal of biological chemistry 2001;276(32):30521-6.
2001: Kimura M; Goto S; Ihara Y; Wada A; Yahiro K; Niidome T; Aoyagi H; Hirayama T; Kondo T
Impairment of glutathione metabolism in human gastric epithelial cells treated with vacuolating cytotoxin from Helicobacter pylori.
Microbial pathogenesis 2001;31(1):29-36.
2001: Tokunaga Y; Niidome T; Hatakeyama T; Aoyagi H
Antibacterial activity of bactenecin 5 fragments and their interaction with phospholipid membranes.
Journal of peptide science : an official publication of the European Peptide Society 2001;7(6):297-304.
2001: Yoshida K; Mukai Y; Niidome T; Takashi C; Tokunaga Y; Hatakeyama T; Aoyagi H
Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity.
The journal of peptide research : official journal of the American Peptide Society 2001;57(2):119-26.
2000: Niidome T; Urakawa M; Sato H; Takahara Y; Anai T; Hatakayama T; Wada A; Hirayama T; Aoyagi H
Gene transfer into hepatoma cells mediated by galactose-modified alpha-helical peptides.
Biomaterials 2000;21(17):1811-9.
2000: Kuwahara H; Funada T; Hatakeyama T; Aoyagi H
Effects of chemical modification of carboxyl groups in the hemolytic lectin CEL-III on its hemolytic and carbohydrate-binding activities.
Bioscience, biotechnology, and biochemistry 2000;64(6):1278-81.
2000: Niidome T; Wakamatsu M; Wada A; Hirayama T; Aoyagi H
Required structure of cationic peptide for oligonucleotide-binding and -delivering into cells.
Journal of peptide science : an official publication of the European Peptide Society 2000;6(6):271-9.
2000: Padilla P I; Wada A; Yahiro K; Kimura M; Niidome T; Aoyagi H; Kumatori A; Anami M; Hayashi T; Fujisawa J; Saito H; Moss J; Hirayama T
Morphologic differentiation of HL-60 cells is associated with appearance of RPTPbeta and induction of Helicobacter pylori VacA sensitivity.
The Journal of biological chemistry 2000;275(20):15200-6.
1999: Yahiro K; Niidome T; Kimura M; Hatakeyama T; Aoyagi H; Kurazono H; Imagawa K i; Wada A; Moss J; Hirayama T
Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase beta.
The Journal of biological chemistry 1999;274(51):36693-9.
1999: Niidome T; Urakawa M; Takaji K; Matsuo Y; Ohmori N; Wada A; Hirayama T; Aoyagi H
Influence of lipophilic groups in cationic alpha-helical peptides on their abilities to bind with DNA and deliver genes into cells.
The journal of peptide research : official journal of the American Peptide Society 1999;54(4):361-7.
1999: Niidome T; Takaji K; Urakawa M; Ohmori N; Wada A; Hirayama T; Aoyagi H
Chain length of cationic alpha-helical peptide sufficient for gene delivery into cells.
Bioconjugate chemistry 1999;10(5):773-80.
1999: Yoshida K; Ohmori N; Mukai Y; Niidome T; Hatakeyama T; Aoyagi H
Interaction of bundled Ser-rich amphiphilic peptides with phospholipid membranes.
Journal of peptide science : an official publication of the European Peptide Society 1999;5(8):360-7.
1999: Hatakeyama T; Kamine T; Konishi Y; Kuwahara H; Niidome T; Aoyagi H
Carbohydrate-dependent hemolytic activity of the conjugate composed of a C-type lectin, CEL-I, and an amphiphilic alpha-helical peptide, 4(3)-beta Ala2.
Bioscience, biotechnology, and biochemistry 1999;63(7):1312-4.
1999: Niidome T; Anzai S; Sonoda J; Tokunaga Y; Nakahara M; Hatakeyama T; Aoyagi H
Effect of amino acid substitution in amphiphilic alpha-helical peptides on peptide-phospholipid membrane interaction.
Journal of peptide science : an official publication of the European Peptide Society 1999;5(7):298-305.
1999: Hatakeyama T; Sato T; Taira E; Kuwahara H; Niidome T; Aoyagi H
Characterization of the interaction of hemolytic lectin CEL-III from the marine invertebrate, Cucumaria echinata, with artificial lipid membranes: involvement of neutral sphingoglycolipids in the pore-forming process.
Journal of biochemistry 1999;125(2):277-84.
1999: Kimura M; Goto S; Wada A; Yahiro K; Niidome T; Hatakeyama T; Aoyagi H; Hirayama T; Kondo T
Vacuolating cytotoxin purified from Helicobacter pylori causes mitochondrial damage in human gastric cells.
Microbial pathogenesis 1999;26(1):45-52.
1998: Hatakeyama T; Matsuyama Y; Funada T; Fukuyama S; Kuwahara H; Aoyagi H; Yamasaki N
Chemical modification of the hemolytic lectin CEL-III by succinic anhydride: involvement of amino groups in the oligomerization process.
Bioscience, biotechnology, and biochemistry 1998;62(6):1185-9.
1998: Niidome T; Mihara H; Oka M; Hayashi T; Saiki T; Yoshida K; Aoyagi H
Structure and property of model peptides of proline/arginine-rich region in bactenecin 5.
The journal of peptide research : official journal of the American Peptide Society 1998;51(5):337-45.
1998: Ohmori N; Niidome T; Kiyota T; Lee S; Sugihara G; Wada A; Hirayama T; Aoyagi H
Importance of hydrophobic region in amphiphilic structures of alpha-helical peptides for their gene transfer-ability into cells.
Biochemical and biophysical research communications 1998;245(1):259-65.
1998: Ohmori N; Niidome T; Hatakeyama T; Mihara H; Aoyagi H
Interaction of alpha-helical peptides with phospholipid membrane: effects of chain length and hydrophobicity of peptides.
The journal of peptide research : official journal of the American Peptide Society 1998;51(2):103-9.
1997: Niidome T; Kawakami R; Okamoto K; Ohmori N; Mihara H; Aoyagi H
Interaction of lipophilic peptides derived from mastoparan with phospholipid vesicles.
The journal of peptide research : official journal of the American Peptide Society 1997;50(6):458-64.
1997: Yahiro K; Niidome T; Hatakeyama T; Aoyagi H; Kurazono H; Padilla P I; Wada A; Hirayama T
Helicobacter pylori vacuolating cytotoxin binds to the 140-kDa protein in human gastric cancer cell lines, AZ-521 and AGS.
Biochemical and biophysical research communications 1997;238(2):629-32.
1997: Niidome T; Kimura M; Chiba T; Ohmori N; Mihara H; Aoyagi H
Membrane interaction of synthetic peptides related to the putative fusogenic region of PH-30 alpha, a protein in sperm-egg fusion.
The journal of peptide research : official journal of the American Peptide Society 1997;49(6):563-9.
1997: Ohmori N; Niidome T; Wada A; Hirayama T; Hatakeyama T; Aoyagi H
The enhancing effect of anionic alpha-helical peptide on cationic peptide-mediating transfection systems.
Biochemical and biophysical research communications 1997;235(3):726-9.
1997: Niidome T; Ohmori N; Ichinose A; Wada A; Mihara H; Hirayama T; Aoyagi H
Binding of cationic alpha-helical peptides to plasmid DNA and their gene transfer abilities into cells.
The Journal of biological chemistry 1997;272(24):15307-12.
1995: Tani A; Lee S; Oishi O; Aoyagi H; Ohno M
Interaction of the fragments characteristic of bactenecin 7 with phospholipid bilayers and their antimicrobial activity.
Journal of biochemistry 1995;117(3):560-5.
1994: Lee S; Tanaka T; Anzai K; Kirino Y; Aoyagi H; Sugihara G
Two mode ion channels induced by interaction of acidic amphipathic alpha-helical peptides with lipid bilayers.
Biochimica et biophysica acta 1994;1191(1):181-9.
1994: Kato T; Lee S; Oishi O; Aoyagi H; Ohno M
Interactions of N-terminal fragments of groups I and II phospholipases A2 with phospholipid bilayers and their surface recognition properties.
Biochimica et biophysica acta 1994;1211(2):215-20.
1994: Iwata T; Lee S; Oishi O; Aoyagi H; Ohno M; Anzai K; Kirino Y; Sugihara G
Design and synthesis of amphipathic 3(10)-helical peptides and their interactions with phospholipid bilayers and ion channel formation.
The Journal of biological chemistry 1994;269(7):4928-33.
1994: Shinozaki K; Anzai K; Kirino Y; Lee S; Aoyagi H
Ion channel activity of a synthetic peptide with a primary structure corresponding to the presumed pore-forming region of the voltage dependent potassium channel.
Biochemical and biophysical research communications 1994;198(2):445-50.
1993: Lee S; Iwata T; Oyagi H; Aoyagi H; Ohno M; Anzai K; Kirino Y; Sugihara G
Effect of salts on conformational change of basic amphipathic peptides from beta-structure to alpha-helix in the presence of phospholipid liposomes and their channel-forming ability.
Biochimica et biophysica acta 1993;1151(1):76-82.
1992: Park N G; Lee S; Oishi O; Aoyagi H; Iwanaga S; Yamashita S; Ohno M
Conformation of tachyplesin I from Tachypleus tridentatus when interacting with lipid matrices.
Biochemistry 1992;31(48):12241-7.
1992: Kato T; Mizuno H; Lee S; Aoyagi H; Kodama H; Go N; Kato T
Survey of conformational role of ester bonds in a cyclic depsipeptide. Study on cyclo(-L-Ala-L-Hmb-)2 by energy calculation and NMR spectroscopy.
International journal of peptide and protein research 1992;39(6):485-92.
1992: Aoyagi H; Waki K; Kato T; Lee S; Yamasaki H; Furuya S
Interaction of amino acid-substituted partial extension peptides of adrenodoxin precursor with artificial membranes and isolated mitochondria.
Peptide research 1992;5(2):91-6.
1992: Ueda T; Kiyohara K; Lee S; Aoyagi H; Izumiya N
Four diastereoisomers of cyclo(-Asp-Val-): inconsistency of their properties with the proposed structure of cairomycin A.
The Journal of antibiotics 1992;45(2):235-9.
1992: Lee S; Aoki R; Oishi O; Aoyagi H; Yamasaki N
Effect of amphipathic peptides with different alpha-helical contents on liposome-fusion.
Biochimica et biophysica acta 1992;1103(1):157-62.
1991: Agawa Y; Lee S; Ono S; Aoyagi H; Ohno M; Taniguchi T; Anzai K; Kirino Y
Interaction with phospholipid bilayers, ion channel formation, and antimicrobial activity of basic amphipathic alpha-helical model peptides of various chain lengths.
The Journal of biological chemistry 1991;266(30):20218-22.
1991: Anzai K; Hamasuna M; Kadono H; Lee S; Aoyagi H; Kirino Y
Formation of ion channels in planar lipid bilayer membranes by synthetic basic peptides.
Biochimica et biophysica acta 1991;1064(2):256-66.
1991: Kato T; Lee S; Ono S; Agawa Y; Aoyagi H; Ohno M; Nishino N
Conformational studies of amphipathic alpha-helical peptides containing an amino acid with a long alkyl chain and their anchoring to lipid bilayer liposomes.
Biochimica et biophysica acta 1991;1063(2):191-6.
1990: Nakamura H; Lee S; Ono S; Kato T; Aoyagi H
Side reaction of pyrenylalanine-peptides containing NG-tosylarginine during detosylation with hydrogen fluoride.
International journal of peptide and protein research 1990;36(5):471-5.
1990: Ono S; Lee S; Mihara H; Aoyagi H; Kato T; Yamasaki N
Design and synthesis of basic peptides having amphipathic beta-structure and their interaction with phospholipid membranes.
Biochimica et biophysica acta 1990;1022(2):237-44.
1989: Lee S; Yoshida M; Mihara H; Aoyagi H; Kato T; Yamasaki N
The spectroscopic analysis for binding of amphipathic and antimicrobial model peptides containing pyrenylalanine and tryptophan to lipid bilayer.
Biochimica et biophysica acta 1989;984(2):174-82.
1989: Suenaga M; Lee S; Park N G; Aoyagi H; Kato T; Umeda A; Amako K
Basic amphipathic helical peptides induce destabilization and fusion of acidic and neutral liposomes.
Biochimica et biophysica acta 1989;981(1):143-50.
1989: Park N G; Aoyagi H; Lee S; Kato T; Jinkawa S; Ou W; Ito A
Effects of model extension peptides containing glycine, proline and serine residues on the import of mitochondrial enzyme precursors into mitochondria.
Peptide research 1989;2(2):178-83.
1988: Aoyagi H; Lee S; Nakamura H; Park N G; Kato T
Interaction of basic extension peptide fragments of adrenodoxin precursor with phospholipid vesicles.
International journal of peptide and protein research 1988;32(5):406-14.
1988: Harano T; Miyata T; Lee S; Aoyagi H; Omura T
Biosynthesis and localization of rat liver microsomal carboxyesterase E1.
Journal of biochemistry 1988;103(1):149-55.
1987: Mihara H; Lee S; Shimohigashi Y; Aoyagi H; Kato T; Izumiya N; Costa T
Synthesis, receptor binding activity and fluorescence property of fluorescent enkephalin analogs containing L-1-pyrenylalanine.
International journal of peptide and protein research 1987;30(5):605-12.
1987: Furuya S; Okada M; Ito A; Aoyagi H; Kanmera T; Kato T; Sagara Y; Horiuchi T; Omura T
Synthetic partial extension peptides of P-450(SCC) and adrenodoxin precursors: effects on the import of mitochondrial enzyme precursors.
Journal of biochemistry 1987;102(4):821-32.
1987: Aoyagi H; Lee S; Kanmera T; Mihara H; Kato T
Interaction of synthetic fragments of the extension peptide of cytochrome P-450(SCC) precursor with phospholipid bilayer.
Journal of biochemistry 1987;102(4):813-20.
1985: Ito A; Ogishima T; Ou W; Omura T; Aoyagi H; Lee S; Mihara H; Izumiya N
Effects of synthetic model peptides resembling the extension peptides of mitochondrial enzyme precursors on import of the precursors into mitochondria.
Journal of biochemistry 1985;98(6):1571-82.
1985: Mihara H; Aoyagi H; Yonezawa H; Kuromizu K; Izumiya N
Synthesis of analogs of K-582A, an antibiotic heptapeptide.
International journal of peptide and protein research 1985;25(6):640-7.
1982: Yasutake A; Aoyagi H; Sada I; Kato T; Izumiya N
Cyclic peptides. XIV. Syntheses of [4-l-leucine]-, [4-D-leucine]-, and [3-L-proline, 4-D-leucine]-Cyl-2.
International journal of peptide and protein research 1982;20(3):246-53.
1981: Miyazaki K; Yasutake A; Nishino N; Aoyagi H; Kato T; Izumiya N
Cyclic peptides. X. Bitter taste and chymotryptic hydrolysis of cyclic depsidipeptides containing a tryptophan residue.
International journal of peptide and protein research 1981;17(1):118-24.
1980: Kanmera T; Lee S; Aoyagi H; Izumiya N
Cyclic peptides. IX. Asymmetric hydrogenation of alpha, beta-dehydroamino acid residue in cyclodipeptides and preparation of optically pure alpha-amino acids.
International journal of peptide and protein research 1980;16(4):280-90.
1980: Yasutake A; Miyazaki K; Aoyagi H; Kato T; Izumiya N
Cyclic peptides. VIII. Synthesis and tryptic hydrolysis of cyclic depsidipeptides containing a lysine residue.
International journal of peptide and protein research 1980;16(1):61-5.
1980: Yasutake A; Aoyagi H; Kato T; Izumiya N
Cyclic peptides. VII. Synthesis and conformation of diastereomeric analogs of cyl-2 containing L-proline and L-leucine.
International journal of peptide and protein research 1980;15(2):113-21.

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