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Karen Gale

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David Dybdal; Patrick A Forcelli; Angela Holmes; Ludise Malkova; Michael Oppedisano; Mark Dubach; Karen Gale
Topography of dyskinesias and torticollis evoked by inhibition of substantia nigra pars reticulata.
Jacqueline T DesJardin; Patrick A Forcelli; John T Gale; Karen Gale; Angela L Holmes; Claire E Cole; Laurie L Wellman; Ludise Malkova
Defense-like behaviors evoked by pharmacological disinhibition of the superior colliculus in the primate.
Patrick A Forcelli; Karen Gale; Anthony D Kammerich; Yohani P Kayinamura; Brian C-W Lee; Laura H Rubinson; Cameron T Sweeney; Judith F Rubinson
Histocompatibility and in vivo signal throughput for PEDOT, PEDOP, P3MT, and polycarbazole electrodes.

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All Publications

2013: David Dybdal; Patrick A Forcelli; Angela Holmes; Ludise Malkova; Michael Oppedisano; Mark Dubach; Karen Gale
Topography of dyskinesias and torticollis evoked by inhibition of substantia nigra pars reticulata.
Movement disorders : official journal of the Movement Disorder Society 2013;28(4):460-8.
2013: Jacqueline T DesJardin; Patrick A Forcelli; John T Gale; Karen Gale; Angela L Holmes; Claire E Cole; Laurie L Wellman; Ludise Malkova
Defense-like behaviors evoked by pharmacological disinhibition of the superior colliculus in the primate.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(1):150-5.
2012: Patrick A Forcelli; Karen Gale; Anthony D Kammerich; Yohani P Kayinamura; Brian C-W Lee; Laura H Rubinson; Cameron T Sweeney; Judith F Rubinson
Histocompatibility and in vivo signal throughput for PEDOT, PEDOP, P3MT, and polycarbazole electrodes.
Journal of biomedical materials research. Part A 2012;100(12):3455-62.
2012: Angela L Holmes; Ludise Malkova; Menna Teferra; Elizabeth A West; Ashley L Decker; Jacqueline T DesJardin; Patrick A Forcelli; Karen Gale
Superior colliculus mediates cervical dystonia evoked by inhibition of the substantia nigra pars reticulata.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(38):13326-32.
2012: Patrick A Forcelli; Megan J Janssen; Stefano Vicini; Karen Gale
Neonatal exposure to antiepileptic drugs disrupts striatal synaptic development.
Annals of neurology 2012;72(3):363-72.
2012: Elizabeth A West; Patrick A Forcelli; Karen Gale; David L McCue; Alice T Murnen; Ludise Malkova
Transient inactivation of basolateral amygdala during selective satiation disrupts reinforcer devaluation in rats.
Behavioral neuroscience 2012;126(4):563-74.
2012: Patrick A Forcelli; Karen Gale; Anand Lakhkar; Colin Soper; Alexei D. Kondratyev
Anticonvulsant effect of retigabine during postnatal development in rats.
Epilepsy research 2012;101(1-2):135-40.
2012: Patrick A Forcelli; Alexei D. Kondratyev; Ryan Kozlowski; Charles Snyder; Karen Gale
Effects of neonatal antiepileptic drug exposure on cognitive, emotional, and motor function in adult rats.
The Journal of pharmacology and experimental therapeutics 2012;340(3):558-66.
2011: Patrick A Forcelli; Jinsook Kim; Alexei D. Kondratyev; Karen Gale
Pattern of antiepileptic drug-induced cell death in limbic regions of the neonatal rat brain.
Epilepsia 2011;52(12):e207-11.
2011: Elizabeth A West; Jacqueline T DesJardin; Karen Gale; Ludise Malkova
Transient inactivation of orbitofrontal cortex blocks reinforcer devaluation in macaques.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(42):15128-35.
2011: Ludise Malkova; Alan P Kozikowski; Karen Gale
The effects of huperzine A and IDRA 21 on visual recognition memory in young macaques.
Neuropharmacology 2011;60(7-8):1262-8.
2011: Samantha L Crowe; Susanna Tsukerman; Karen Gale; Timothy Jorgensen; Alexei D. Kondratyev
Phosphorylation of histone H2A.X as an early marker of neuronal endangerment following seizures in the adult rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(21):7648-56.
2011: Patrick A Forcelli; Karen Gale; Alexei D. Kondratyev
Early postnatal exposure of rats to lamotrigine, but not phenytoin, reduces seizure threshold in adulthood.
Epilepsia 2011;52(4):e20-2.
2011: Elizabeth A West; Patrick A Forcelli; Alice Murnen; Karen Gale; Ludise Malkova
A visual, position-independent instrumental reinforcer devaluation task for rats.
Journal of neuroscience methods 2011;194(2):297-304.
2010: Patrick A Forcelli; Megan J Janssen; Lauren A Stamps; Cameron Sweeney; Stefano Vicini; Karen Gale
Therapeutic strategies to avoid long-term adverse outcomes of neonatal antiepileptic drug exposure.
Epilepsia 2010;51 Suppl 3():18-23.
2010: Jinsook Kim; Karen Gale; Alexei Kondratyev
Effects of repeated minimal electroshock seizures on NGF, BDNF and FGF-2 protein in the rat brain during postnatal development.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2010;28(3):227-32.
2009: Giuseppe Conti; Karen Gale; Alexei D. Kondratyev
Immunohistochemical evaluation of the protein expression of nerve growth factor and its TrkA receptor in rat limbic regions following electroshock seizures.
Neuroscience research 2009;65(2):201-9.
2007: Jinsook Kim; Alexei D. Kondratyev; Karen Gale
Antiepileptic drug-induced neuronal cell death in the immature brain: effects of carbamazepine, topiramate, and levetiracetam as monotherapy versus polytherapy.
The Journal of pharmacology and experimental therapeutics 2007;323(1):165-73.
2007: Irina Katz; Jinsook Kim; Karen Gale; Alexei D. Kondratyev
Effects of lamotrigine alone and in combination with MK-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain.
The Journal of pharmacology and experimental therapeutics 2007;322(2):494-500.
2007: Jin-Sook Kim; Alexei D. Kondratyev; York Tomita; Karen Gale
Neurodevelopmental impact of antiepileptic drugs and seizures in the immature brain.
Epilepsia 2007;48 Suppl 5():19-26.
2005: Laurie L Wellman; Karen Gale; Ludise Malkova
GABAA-mediated inhibition of basolateral amygdala blocks reward devaluation in macaques.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(18):4577-86.
2005: Francesco Fornai; Carla L Busceti; Alexei D. Kondratyev; Karen Gale
AMPA receptor desensitization as a determinant of vulnerability to focally evoked status epilepticus.
The European journal of neuroscience 2005;21(2):455-63.
2004: Alexei D. Kondratyev; Karen Gale
Latency to onset of status epilepticus determines molecular mechanisms of seizure-induced cell death.
Brain research. Molecular brain research 2004;121(1-2):86-94.
2003: Kristen A Richardson; Bruce J Gluckman; Steven L Weinstein; Caryn E Glosch; Jessica B Moon; Ryder P Gwinn; Karen Gale; Steven J Schiff
In vivo modulation of hippocampal epileptiform activity with radial electric fields.
Epilepsia 2003;44(6):768-77.
2002: Alexei D. Kondratyev; Dawn Selby; Karen Gale
Status epilepticus leads to the degradation of the endogenous inhibitor of caspase-activated DNase in rats.
Neuroscience letters 2002;319(3):145-8.
2002: Alexei D. Kondratyev; R Ved; Karen Gale
The effects of repeated minimal electroconvulsive shock exposure on levels of mRNA encoding fibroblast growth factor-2 and nerve growth factor in limbic regions.
Neuroscience 2002;114(2):411-6.
2002: Ryder P Gwinn; Alexei D. Kondratyev; Karen Gale
Time-dependent increase in basic fibroblast growth factor protein in limbic regions following electroshock seizures.
Neuroscience 2002;114(2):403-9.
2001: Alexei D. Kondratyev; Karen Gale
Temporal and spatial patterns of DNA fragmentation following focally or systemically-evoked status epilepticus in rats.
Neuroscience letters 2001;310(1):13-6.
2001: Alexei D. Kondratyev; Niaz Sahibzada; Karen Gale
Electroconvulsive shock exposure prevents neuronal apoptosis after kainic acid-evoked status epilepticus.
Brain research. Molecular brain research 2001;91(1-2):1-13.
2000: D Dybdal; Karen Gale
Postural and anticonvulsant effects of inhibition of the rat subthalamic nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(17):6728-33.
2000: Alexei D. Kondratyev; Karen Gale
Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus.
Brain research. Molecular brain research 2000;75(2):216-24.
1999: Benjamin R Walker; A Easton; Karen Gale
Regulation of limbic motor seizures by GABA and glutamate transmission in nucleus tractus solitarius.
Epilepsia 1999;40(8):1051-7.
1999: D Masco; Niaz Sahibzada; R Switzer; Karen Gale
Electroshock seizures protect against apoptotic hippocampal cell death induced by adrenalectomy.
Neuroscience 1999;91(4):1315-9.
1998: Robert Cassidy; Karen Gale
Mediodorsal thalamus plays a critical role in the development of limbic motor seizures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(21):9002-9.
1998: K C New; Karen Gale; Robert L Martuza; samuel rabkin
Novel synthesis and release of GABA in cerebellar granule cell cultures after infection with defective herpes simplex virus vectors expressing glutamic acid decarboxylase.
Brain research. Molecular brain research 1998;61(1-2):121-35.
1997: A Tortorella; T Halonen; Niaz Sahibzada; Karen Gale
A crucial role of the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype of glutamate receptors in piriform and perirhinal cortex for the initiation and propagation of limbic motor seizures.
The Journal of pharmacology and experimental therapeutics 1997;280(3):1401-5.
1997: M R Proctor; Francesco Fornai; J K Afshar; Karen Gale
The role of nitric oxide in focally-evoked limbic seizures.
Neuroscience 1997;76(4):1231-6.
1996: A Pasini; A Tortorella; Karen Gale
The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin.
Brain research 1996;724(1):84-8.
1995: R Meloni; Karen Gale
Activation of tyrosine hydroxylase by haloperidol in fetal nigral transplants.
Neuroreport 1995;6(4):666-8.
1995: Karen Gale
Chemoconvulsant seizures: advantages of focally-evoked seizure models.
Italian journal of neurological sciences 1995;16(1-2):17-25.
1994: T Halonen; A Tortorella; H Zrebeet; Karen Gale
Posterior piriform and perirhinal cortex relay seizures evoked from the area tempestas: role of excitatory and inhibitory amino acid receptors.
Brain research 1994;652(1):145-8.
1994: P Follesa; Karen Gale; Italo Mocchetti
Regional and temporal pattern of expression of nerve growth factor and basic fibroblast growth factor mRNA in rat brain following electroconvulsive shock.
Experimental neurology 1994;127(1):37-44.
1994: F Fornai; D J Dybdal; M R Proctor; Karen Gale
Focal intracerebral elevation of L-lactate is anticonvulsant.
European journal of pharmacology 1994;254(3):R1-2.
1994: P J Karstaedt; H Kerasidis; J H Pincus; R Meloni; J Graham; Karen Gale
Unilateral destruction of dopamine pathways increases ipsilateral striatal serotonin turnover in rats.
Experimental neurology 1994;126(1):25-30.
1993: R Browning; R Maggio; Niaz Sahibzada; Karen Gale
Role of brainstem structures in seizures initiated from the deep prepiriform cortex of rats.
Epilepsia 1993;34(3):393-407.
1993: S Prendiville; Karen Gale
Anticonvulsant effect of fluoxetine on focally evoked limbic motor seizures in rats.
Epilepsia 1993;34(2):381-4.
1993: Karen Gale; A Pazos; R Maggio; K Japikse; P Pritchard
Blockade of GABA receptors in superior colliculus protects against focally evoked limbic motor seizures.
Brain research 1993;603(2):279-83.
1993: P Lanaud; R Maggio; Karen Gale; Dennis Grayson
Temporal and spatial patterns of expression of c-fos, zif/268, c-jun and jun-B mRNAs in rat brain following seizures evoked focally from the deep prepiriform cortex.
Experimental neurology 1993;119(1):20-31.
1993: R Maggio; P Lanaud; Dennis Grayson; Karen Gale
Expression of c-fos mRNA following seizures evoked from an epileptogenic site in the deep prepiriform cortex: regional distribution in brain as shown by in situ hybridization.
Experimental neurology 1993;119(1):11-9.
1992: A Pasini; A Tortorella; Karen Gale
Anticonvulsant effect of intranigral fluoxetine.
Brain research 1992;593(2):287-90.
1992: C J Peterson; S Vinayak; A Pazos; Karen Gale
A rodent model of focally evoked self-sustaining status epilepticus.
European journal of pharmacology 1992;221(1):151-5.
1992: MARCO RIVA; Karen Gale; Italo Mocchetti
Basic fibroblast growth factor mRNA increases in specific brain regions following convulsive seizures.
Brain research. Molecular brain research 1992;15(3-4):311-8.
1992: Karen Gale; P Zhong; L P Miller; T F Murray
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex.
Epilepsy research. Supplement 1992;8():229-34.
1992: Karen Gale
GABA and epilepsy: basic concepts from preclinical research.
Epilepsia 1992;33 Suppl 5():S3-12.
1992: Karen Gale; R Maggio; T Halonen; P Lanaud; Dennis Grayson
Regional changes in immediate early gene expression following focally-evoked limbic motor seizures.
Epilepsy research. Supplement 1992;9():361-9.
1991: R Meloni; Karen Gale
Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra.
European journal of pharmacology 1991;209(1-2):113-7.
1991: J Segovia; R Castro; Vicente Notario; Karen Gale
Transplants of fetal substantia nigra regulate glutamic acid decarboxylase gene expression in host striatal neurons.
Brain research. Molecular brain research 1991;10(4):359-62.
1991: R Maggio; E Sohn; Karen Gale
Lack of proconvulsant action of GABA depletion in substantia nigra in several seizure models.
Brain research 1991;547(1):1-6.
1990: J Segovia; Niranjala J K Tillakaratne; K Whelan; Allan J Tobin; Karen Gale
Parallel increases in striatal glutamic acid decarboxylase activity and mRNA levels in rats with lesions of the nigrostriatal pathway.
Brain research 1990;529(1-2):345-8.
1990: J Wardas; J Graham; Karen Gale
Evidence for a role of glycine in area tempestas for triggering convulsive seizures.
European journal of pharmacology 1990;187(1):59-66.
1990: R Maggio; U Liminga; Karen Gale
Selective stimulation of kainate but not quisqualate or NMDA receptors in substantia nigra evokes limbic motor seizures.
Brain research 1990;528(2):223-30.
1990: R Meloni; Karen Gale
Pharmacological evidence for feedback regulation of dopamine metabolism in solid fetal substantia nigra transplants.
The Journal of pharmacology and experimental therapeutics 1990;253(3):1259-64.
1990: R Meloni; Karen Gale
Differential regulation of dopamine metabolism in solid fetal substantia nigra transplants and their terminals in the host striatum.
Progress in brain research 1990;82():467-71.
1989: M Massotti; Karen Gale
Electroencephalographic evidence for a dose-related biphasic effect of morphine on bicuculline-induced seizures in the rat.
Epilepsy research 1989;4(2):81-9.
1989: R Maggio; Karen Gale
Seizures evoked from area tempestas are subject to control by GABA and glutamate receptors in substantia nigra.
Experimental neurology 1989;105(2):184-8.
1989: J Segovia; R Meloni; Karen Gale
Effect of dopaminergic denervation and transplant-derived reinnervation on a marker of striatal GABAergic function.
Brain research 1989;493(1):185-9.
1989: Karen Gale
GABA in epilepsy: the pharmacologic basis.
Epilepsia 1989;30 Suppl 3():S1-11.
1988: L M Gunne; S E Bachus; Karen Gale
Oral movements induced by interference with nigral GABA neurotransmission: relationship to tardive dyskinesias.
Experimental neurology 1988;100(3):459-69.
1988: Karen Gale
Progression and generalization of seizure discharge: anatomical and neurochemical substrates.
Epilepsia 1988;29 Suppl 2():S15-34.
1988: S E Bachus; Karen Gale
Differential effects of chronic treatment with chlorpromazine versus cocaine on behavioral responsiveness to nigral GABA receptor stimulation.
Psychopharmacology 1988;95(1):56-62.
1987: S Piredda; M Pavlick; Karen Gale
Anticonvulsant effects of GABA elevation in the deep prepiriform cortex.
Epilepsy research 1987;1(2):102-6.
1986: S E Bachus; Karen Gale
Muscimol microinfused into the nigrotegmental target area blocks selected components of behavior elicited by amphetamine or cocaine.
Naunyn-Schmiedeberg's archives of pharmacology 1986;333(2):143-8.
1985: Karen Gale; H Kerasidis; J R Wrathall
Spinal cord contusion in the rat: behavioral analysis of functional neurologic impairment.
Experimental neurology 1985;88(1):123-34.