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Antony Galione

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Anthony J Morgan; John Parrington; Siegfried K T Y Wagner; Grant C Churchill; Lianne C Davis; Alexander M Lewis; Antony Galione
Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organelles.
Lianne C Davis; Duncan Bloor-Young; Vincenzo Cerundolo; Ji-Li Chen; Grant C Churchill; Stuart J Conway; Anthony J Morgan; John Parrington; Eugene Shenderov; Charlotte M Snead; Megan N Stanton-Humphreys; Antony Galione
NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing.
Anthony J Morgan; John Parrington; Antony Galione
The luminal Ca(2+) chelator, TPEN, inhibits NAADP-induced Ca(2+) release.

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2013: Anthony J Morgan; John Parrington; Siegfried K T Y Wagner; Grant C Churchill; Lianne C Davis; Alexander M Lewis; Antony Galione
Bidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organelles.
The Journal of cell biology 2013;200(6):789-805.
2012: Lianne C Davis; Duncan Bloor-Young; Vincenzo Cerundolo; Ji-Li Chen; Grant C Churchill; Stuart J Conway; Anthony J Morgan; John Parrington; Eugene Shenderov; Charlotte M Snead; Megan N Stanton-Humphreys; Antony Galione
NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing.
Current biology : CB 2012;22(24):2331-7.
2012: Anthony J Morgan; John Parrington; Antony Galione
The luminal Ca(2+) chelator, TPEN, inhibits NAADP-induced Ca(2+) release.
Cell calcium 2012;52(6):481-7.
2012: Alexander M Lewis; Roser Masgrau; Claire Paramore; Ali Roomi; Luke E L Sanders; Katherine Shipman; Derek A Terrar; Justyn M Thomas; Parvinder Aley; Duncan Bloor-Young; Antony Galione; Clive Garnham; Grant C Churchill
β-Adrenergic receptor signaling increases NAADP and cADPR levels in the heart.
Biochemical and biophysical research communications 2012;427(2):326-9.
2012: Nina Larisch; Christina Schulze; Antony Galione; Petra Dietrich
An N-terminal dileucine motif directs two-pore channels to the tonoplast of plant cells.
Traffic (Copenhagen, Denmark) 2012;13(7):1012-22.
2012: Timothy F Walseth; Antony Galione; Pooja Jain; Yaping Lin-Moshier; Jonathan S Marchant; John Parrington; Margarida Ruas; James T Slama
Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg.
The Journal of biological chemistry 2012;287(4):2308-15.
2012: Antony Galione; Kai-Ting Chuang
Pyridine nucleotide metabolites and calcium release from intracellular stores.
Advances in experimental medicine and biology 2012;740():305-23.
2011: Junaid Kashir; Hoi-Chang Lee; Dimitra Nikiforaki; John Parrington; Katja Rietdorf; Margarida Ruas; Sze Tian Tee; Petra De Sutter; Claire Durrans; Rafael A Fissore; Antony Galione; Bjorn Heindryckx; Celine Jones; Kevin Coward
Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes.
Human reproduction (Oxford, England) 2011;26(12):3372-87.
2011: Anthony J Morgan; Frances M Platt; Emyr Lloyd-Evans; Antony Galione
Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease.
The Biochemical journal 2011;439(3):349-74.
2011: Thomas P Collins; Antony Galione; Rebecca Bayliss; Grant C Churchill; Derek A Terrar
NAADP influences excitation-contraction coupling by releasing calcium from lysosomes in atrial myocytes.
Cell calcium 2011;50(5):449-58.
2011: Katja Rietdorf; Margarida Ruas; Tim M Funnell; Jennifer Heinemann; John Parrington; Antony Galione
Two-pore channels form homo- and heterodimers.
The Journal of biological chemistry 2011;286(43):37058-62.
2011: Antony Galione; John Parrington; Tim Funnell
Physiological roles of NAADP-mediated Ca2+ signaling.
Science China. Life sciences 2011;54(8):725-32.
2011: Bianca Esposito; Guido Gambara; Alexander M Lewis; Fioretta Palombi; Alessio D'Alessio; Lewis X Taylor; Armando Genazzani; Elio Ziparo; Antony Galione; Grant C Churchill; Antonio Filippini
NAADP links histamine H1 receptors to secretion of von Willebrand factor in human endothelial cells.
Blood 2011;117(18):4968-77.
2011: Christelle Moreau; Gloria A Ashamu; Victoria C Bailey; Antony Galione; Andreas H Guse; Barry V L Potter
Synthesis of cyclic adenosine 5'-diphosphate ribose analogues: a C2'endo/syn "southern" ribose conformation underlies activity at the sea urchin cADPR receptor.
Organic & biomolecular chemistry 2011;9(1):278-90.
2011: Neil S Keddie; Yulin Ye; Tashfeen Aslam; Tomas Luyten; Davide Bello; Clive Garnham; Geert Bultynck; Antony Galione; Stuart J Conway
Development of inositol-based antagonists for the D-myo-inositol 1,4,5-trisphosphate receptor.
Chemical communications (Cambridge, England) 2011;47(1):242-4.
2011: Antony Galione
NAADP receptors.
Cold Spring Harbor perspectives in biology 2011;3(1):a004036.
2010: François Cosker; Nathalie Cheviron; Michiko Yamasaki; Alexis Menteyne; Frances E Lund; Marie-Jo Moutin; Antony Galione; Jose-Manuel Cancela
The ecto-enzyme CD38 is a nicotinic acid adenine dinucleotide phosphate (NAADP) synthase that couples receptor activation to Ca2+ mobilization from lysosomes in pancreatic acinar cells.
The Journal of biological chemistry 2010;285(49):38251-9.
2010: Antony Galione; Anthony J Morgan; Abdelilah Arredouani; Lianne C Davis; Katja Rietdorf; Margarida Ruas; John Parrington
NAADP as an intracellular messenger regulating lysosomal calcium-release channels.
Biochemical Society transactions 2010;38(6):1424-31.
2010: G Cristina Brailoiu; Bogdan Gurzu; Xin Gao; Raman Parkesh; Parvinder K Aley; Diana I Trifa; Antony Galione; Nae J Dun; Muniswamy Madesh; Sandip Patel; Grant C Churchill; Eugen Brailoiu
Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure.
The Journal of biological chemistry 2010;285(48):37133-7.
2010: Parvinder Aley; Anna M Mikolajczyk; Barbara Munz; Grant C Churchill; Antony Galione; Felicitas Berger
Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channels.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(46):19927-32.
2010: Samantha J Pitt; Tim M Funnell; Mano Sitsapesan; Elisa Venturi; Katja Rietdorf; Margarida Ruas; A Ganesan; Rajendra Gosain; Grant C Churchill; Michael X Zhu; John Parrington; Antony Galione; Rebecca Sitsapesan
TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+.
The Journal of biological chemistry 2010;285(45):35039-46.
2010: Abdelilah Arredouani; A Mark Evans; Jianjie Ma; John Parrington; Michael X Zhu; Antony Galione
An emerging role for NAADP-mediated Ca2+ signaling in the pancreatic β-cell.
Islets 2010;2(5):323-30.
2010: Nezahat Tugba Durlu-Kandilci; Margarida Ruas; Kai-Ting Chuang; Alison Brading; John Parrington; Antony Galione
TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle.
The Journal of biological chemistry 2010;285(32):24925-32.
2010: Sridhar R Vasudevan; Alexander M Lewis; Jennifer W Chan; Claire L Machin; Debroshi Sinha; Antony Galione; Grant C Churchill
The calcium-mobilizing messenger nicotinic acid adenine dinucleotide phosphate participates in sperm activation by mediating the acrosome reaction.
The Journal of biological chemistry 2010;285(24):18262-9.
2010: Michael X Zhu; Jianjie Ma; John Parrington; Antony Galione; A Mark Evans
TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP.
FEBS letters 2010;584(10):1966-74.
2010: Margarida Ruas; John A Ward; Keiko Watanabe; Gary M Wessel; Michael X Zhu; Abdelilah Arredouani; Xiaotong Cheng; Grant C Churchill; Lianne C Davis; Timothy M Funnell; Heidi Koegel; Emyr Lloyd-Evans; Anthony J Morgan; John Parrington; Frances M Platt; Katja Rietdorf; Antony Galione
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking.
Current biology : CB 2010;20(8):703-9.
2010: Michael X Zhu; Jianjie Ma; John Parrington; Peter J Calcraft; Antony Galione; A Mark Evans
Calcium signaling via two-pore channels: local or global, that is the question.
American journal of physiology. Cell physiology 2010;298(3):C430-41.
2010: Ji-Li Chen; Anthony J Morgan; Guillaume Stewart-Jones; Dawn Shepherd; Giovanna Bossi; Linda Wooldridge; Sarah L Hutchinson; Andrew K Sewell; Gillian M Griffiths; Philip van der Merwe; E Yvonne Jones; Antony Galione; Vincenzo Cerundolo
Ca2+ release from the endoplasmic reticulum of NY-ESO-1-specific T cells is modulated by the affinity of TCR and by the use of the CD8 coreceptor.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(4):1829-39.
2010: Michael X Zhu; A Mark Evans; Jianjie Ma; John Parrington; Antony Galione
Two-pore channels for integrative Ca signaling.
Communicative & integrative biology 2010;3(1):12-7.
2009: Daniel Rosen; Alexander M Lewis; Akiko Mizote; Justyn M Thomas; Parvinder Aley; Sridhar R Vasudevan; Raman Parkesh; Antony Galione; Minoru Izumi; A Ganesan; Grant C Churchill
Analogues of the nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist Ned-19 indicate two binding sites on the NAADP receptor.
The Journal of biological chemistry 2009;284(50):34930-4.
2009: Antony Galione; A Mark Evans; Jianjie Ma; John Parrington; Abdelilah Arredouani; Xiaotong Cheng; Michael X Zhu
The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels.
Pflügers Archiv : European journal of physiology 2009;458(5):869-76.
2009: Peter J Calcraft; Margarida Ruas; Zui Pan; Xiaotong Cheng; Abdelilah Arredouani; Xuemei Hao; Jisen Tang; Katja Rietdorf; Lydia Teboul; Kai-Ting Chuang; Peihui Lin; Rui Xiao; Chunbo Wang; Yingmin Zhu; Yakang Lin; Christopher N Wyatt; John Parrington; Jianjie Ma; A Mark Evans; Antony Galione; Michael X Zhu
NAADP mobilizes calcium from acidic organelles through two-pore channels.
Nature 2009;459(7246):596-600.
2009: Edmund Naylor; Abdelilah Arredouani; Sridhar R Vasudevan; Alexander M Lewis; Raman Parkesh; Akiko Mizote; Daniel Rosen; Justyn M Thomas; Minoru Izumi; A Ganesan; Antony Galione; Grant C Churchill
Identification of a chemical probe for NAADP by virtual screening.
Nature chemical biology 2009;5(4):220-6.
2009: G Cristina Brailoiu; Eugen Brailoiu; Raman Parkesh; Antony Galione; Grant C Churchill; Sandip Patel; Nae J Dun
NAADP-mediated channel 'chatter' in neurons of the rat medulla oblongata.
The Biochemical journal 2009;419(1):91-7, 2 p following 97.
2008: Emyr Lloyd-Evans; Anthony J Morgan; Xingxuan He; David A Smith; Elena Elliot-Smith; Dan J Sillence; Grant C Churchill; Edward H Schuchman; Antony Galione; Frances M Platt
Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.
Nature medicine 2008;14(11):1247-55.
2008: Anthony J Morgan; Antony Galione
Investigating cADPR and NAADP in intact and broken cell preparations.
Methods (San Diego, Calif.) 2008;46(3):194-203.
2008: Lianne C Davis; Anthony J Morgan; Margarida Ruas; Julian L Wong; Richard M Graeff; Albert J Poustka; Hon Cheung Lee; Gary M Wessel; John Parrington; Antony Galione
Ca(2+) signaling occurs via second messenger release from intraorganelle synthesis sites.
Current biology : CB 2008;18(20):1612-8.
2008: Raman Parkesh; Alexander M Lewis; Parvinder Aley; Abdelilah Arredouani; Sara Rossi; Ricardo Tavares; Sridhar R Vasudevan; Daniel Rosen; Antony Galione; James Dowden; Grant C Churchill
Cell-permeant NAADP: a novel chemical tool enabling the study of Ca2+ signalling in intact cells.
Cell calcium 2008;43(6):531-8.
2008: Sridhar R Vasudevan; Antony Galione; Grant C Churchill
Sperm express a Ca2+-regulated NAADP synthase.
The Biochemical journal 2008;411(1):63-70.
2008: Bo Zhang; Gerd K Wagner; Karin Weber; Clive Garnham; Anthony J Morgan; Antony Galione; Andreas H Guse; Barry V L Potter
2'-deoxy cyclic adenosine 5'-diphosphate ribose derivatives: importance of the 2'-hydroxyl motif for the antagonistic activity of 8-substituted cADPR derivatives.
Journal of medicinal chemistry 2008;51(6):1623-36.
2007: Anthony J Morgan; Antony Galione
Fertilization and nicotinic acid adenine dinucleotide phosphate induce pH changes in acidic Ca(2+) stores in sea urchin eggs.
The Journal of biological chemistry 2007;282(52):37730-7.
2007: Alexander M Lewis; Roser Masgrau; Sridhar R Vasudevan; Michiko Yamasaki; John S O'Neill; Clive Garnham; Kristin James; Andrew Macdonald; Mathias Ziegler; Antony Galione; Grant C Churchill
Refinement of a radioreceptor binding assay for nicotinic acid adenine dinucleotide phosphate.
Analytical biochemistry 2007;371(1):26-36.
2007: Bikram P Choudhary; Charalambos Antoniades; Alison F Brading; Antony Galione; Keith M Channon; David P Taggart
Diabetes mellitus as a predictor for radial artery vasoreactivity in patients undergoing coronary artery bypass grafting.
Journal of the American College of Cardiology 2007;50(11):1047-53.
2007: John Parrington; Lianne C Davis; Antony Galione; Gary Wessel
Flipping the switch: how a sperm activates the egg at fertilization.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(8):2027-38.
2007: Andrew T Macgregor; Stevan Rakovic; Antony Galione; Derek A Terrar
Dual effects of cyclic ADP-ribose on sarcoplasmic reticulum Ca2+ release and storage in cardiac myocytes isolated from guinea-pig and rat ventricle.
Cell calcium 2007;41(6):537-46.
2007: Andrew Macgregor; Michiko Yamasaki; Stevan Rakovic; Luke Sanders; Raman Parkesh; Grant C Churchill; Antony Galione; Derek A Terrar
NAADP controls cross-talk between distinct Ca2+ stores in the heart.
The Journal of biological chemistry 2007;282(20):15302-11.
2007: Anthony J Morgan; Antony Galione
NAADP induces pH changes in the lumen of acidic Ca2+ stores.
The Biochemical journal 2007;402(2):301-10.
2007: Raman Parkesh; Sridhar R Vasudevan; Alexandra Berry; Antony Galione; James Dowden; Grant C Churchill
Chemo-enzymatic synthesis and biological evaluation of photolabile nicotinic acid adenine dinuclotide phosphate (NAADP+).
Organic & biomolecular chemistry 2007;5(3):441-3.
2007: Sandra Soares; Michael Thompson; Thomas White; Amir Isbell; Michiko Yamasaki; Yedatore S Prakash; Frances E Lund; Antony Galione; Eduardo N Chini
NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells.
American journal of physiology. Cell physiology 2007;292(1):C227-39.
2006: Antony Galione
NAADP, a new intracellular messenger that mobilizes Ca2+ from acidic stores.
Biochemical Society transactions 2006;34(Pt 5):922-6.
2006: James Dowden; Georgina Berridge; Christelle Moreau; Michiko Yamasaki; Grant C Churchill; Barry V L Potter; Antony Galione
Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release.
Chemistry & biology 2006;13(6):659-65.
2006: Nael Nadif Kasri; Katalin Török; Antony Galione; Clive Garnham; Geert Callewaert; Ludwig Missiaen; Jan B Parys; Humbert De Smedt
Endogenously bound calmodulin is essential for the function of the inositol 1,4,5-trisphosphate receptor.
The Journal of biological chemistry 2006;281(13):8332-8.
2006: A Mark Evans; D Grahame Hardie; Antony Galione; Chris Peers; Prem Kumar; Christopher N Wyatt
AMP-activated protein kinase couples mitochondrial inhibition by hypoxia to cell-specific Ca2+ signalling mechanisms in oxygen-sensing cells.
Novartis Foundation symposium 2006;272():234-52; discussion 252-8, 274-9.
2005: Michiko Yamasaki; Grant C Churchill; Antony Galione
Calcium signalling by nicotinic acid adenine dinucleotide phosphate (NAADP).
The FEBS journal 2005;272(18):4598-606.
2005: Antony Galione; Margarida Ruas
NAADP receptors.
Cell calcium 2005;38(3-4):273-80.
2005: Michiko Yamasaki; Justyn M Thomas; Grant C Churchill; Clive Garnham; Alexander M Lewis; Jose M Cancela; Sandip Patel; Antony Galione
Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells.
Current biology : CB 2005;15(9):874-8.
2005: Antony Galione; Ole H Petersen
The NAADP receptor: new receptors or new regulation?
Molecular interventions 2005;5(2):73-9.
2005: James Dowden; Richard S Brown; Christelle Moreau; Antony Galione; Barry V L Potter
Chemical synthesis of the novel Ca2+ messenger NAADP.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):513-8.
2004: Nicholas P Kinnear; François-Xavier Boittin; Justyn M Thomas; Antony Galione; A Mark Evans
Lysosome-sarcoplasmic reticulum junctions. A trigger zone for calcium signaling by nicotinic acid adenine dinucleotide phosphate and endothelin-1.
The Journal of biological chemistry 2004;279(52):54319-26.
2004: James Dowden; Christelle Moreau; Richard S Brown; Georgina Berridge; Antony Galione; Barry V L Potter
Chemical synthesis of the second messenger nicotinic acid adenine dinucleotide phosphate by total synthesis of nicotinamide adenine dinucleotide phosphate.
Angewandte Chemie (International ed. in English) 2004;43(35):4637-40.
2004: Antony Galione; John Parrington; James Dowden
The NAADP receptor: commentary on Billington et al.
British journal of pharmacology 2004;142(8):1203-7.
2004: Michiko Yamasaki; Roser Masgrau; Anthony J Morgan; Grant C Churchill; Sandip Patel; Stephen J H Ashcroft; Antony Galione
Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells.
The Journal of biological chemistry 2004;279(8):7234-40.
2004: Christopher J W Mort; Marie E Migaud; Antony Galione; Barry V L Potter
Aplysia californica mediated cyclisation of novel 3'-modified NAD+ analogues: a role for hydrogen bonding in the recognition of cyclic adenosine 5'-diphosphate ribose.
Bioorganic & medicinal chemistry 2004;12(2):475-87.
2003: Satoshi Shuto; Masayoshi Fukuoka; Takashi Kudoh; Clive Garnham; Antony Galione; Barry V L Potter; Akira Matsuda
Convergent synthesis and unexpected Ca(2+)-mobilizing activity of 8-substituted analogues of cyclic ADP-carbocyclic-ribose, a stable mimic of the Ca(2+)-mobilizing second messenger cyclic ADP-ribose.
Journal of medicinal chemistry 2003;46(22):4741-9.
2003: Kethurah P Howell; Aurelia Skipwith; Antony Galione; William R Eckberg
Phospholipase C-dependent Ca2+ release by worm and mammal sperm factors.
Biochemical and biophysical research communications 2003;307(1):47-51.
2003: Calum P Leckie; Ruth Empson; Andrea Becchetti; Justyn Thomas; Antony Galione; Michael Whitaker
The NO pathway acts late during the fertilization response in sea urchin eggs.
The Journal of biological chemistry 2003;278(14):12247-54.
2003: François-Xavier Boittin; Michelle Dipp; Nicholas P Kinnear; Antony Galione; A Mark Evans
Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose.
The Journal of biological chemistry 2003;278(11):9602-8.
2003: Roser Masgrau; Grant C Churchill; Anthony J Morgan; Stephen J H Ashcroft; Antony Galione
NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cells.
Current biology : CB 2003;13(3):247-51.
2003: Grant C Churchill; John S O'Neill; Roser Masgrau; Sandip Patel; Justyn M Thomas; Armando Genazzani; Antony Galione
Sperm deliver a new second messenger: NAADP.
Current biology : CB 2003;13(2):125-8.
2002: François-Xavier Boittin; Antony Galione; A Mark Evans
Nicotinic acid adenine dinucleotide phosphate mediates Ca2+ signals and contraction in arterial smooth muscle via a two-pool mechanism.
Circulation research 2002;91(12):1168-75.
2002: Justyn M Thomas; Robin J Summerhill; Bradley R Fruen; Grant C Churchill; Antony Galione
Calmodulin dissociation mediates desensitization of the cADPR-induced Ca2+ release mechanism.
Current biology : CB 2002;12(23):2018-22.
2002: Grant C Churchill; Yuhei Okada; Justyn M Thomas; Armando Genazzani; Sandip Patel; Antony Galione
NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs.
Cell 2002;111(5):703-8.
2002: Georgina Berridge; George Dickinson; John Parrington; Antony Galione; Sandip Patel
Solubilization of receptors for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate.
The Journal of biological chemistry 2002;277(46):43717-23.
2002: Antony Galione; Grant C Churchill
Interactions between calcium release pathways: multiple messengers and multiple stores.
Cell calcium 2002;32(5-6):343-54.
2002: Georgina Berridge; Rainer Cramer; Antony Galione; Sandip Patel
Metabolism of the novel Ca2+-mobilizing messenger nicotinic acid-adenine dinucleotide phosphate via a 2'-specific Ca2+-dependent phosphatase.
The Biochemical journal 2002;365(Pt 1):295-301.
2002: Flavia Barone; Armando Genazzani; Antonio Conti; Grant C Churchill; Fioretta Palombi; Elio Ziparo; Vincenzo Sorrentino; Antony Galione; Antonio Filippini
A pivotal role for cADPR-mediated Ca2+ signaling: regulation of endothelin-induced contraction in peritubular smooth muscle cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):697-705.
2002: Jose M Cancela; Fabien Van Coppenolle; Antony Galione; Alexei V Tepikin; Ole H Petersen
Transformation of local Ca2+ spikes to global Ca2+ transients: the combinatorial roles of multiple Ca2+ releasing messengers.
The EMBO journal 2002;21(5):909-19.
2001: Justyn M Thomas; Roser Masgrau; Grant C Churchill; Antony Galione
Pharmacological characterization of the putative cADP-ribose receptor.
The Biochemical journal 2001;359(Pt 2):451-7.
2001: S Patel; Grant C Churchill; Antony Galione
Coordination of Ca2+ signalling by NAADP.
Trends in biochemical sciences 2001;26(8):482-9.
2001: Justyn M Thomas; Grant C Churchill; Sandip Patel; Antony Galione
Distinct pharmacology of 2-hydroxycarbazole-induced Ca2+ release in the sea urchin egg.
The Journal of pharmacology and experimental therapeutics 2001;298(2):644-50.
2001: Grant C Churchill; Antony Galione
NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ stores.
The EMBO journal 2001;20(11):2666-71.
2001: Grant C Churchill; Antony Galione
Prolonged inactivation of nicotinic acid adenine dinucleotide phosphate-induced Ca2+ release mediates a spatiotemporal Ca2+ memory.
The Journal of biological chemistry 2001;276(14):11223-5.
2001: Heather Wilson; Michelle Dipp; Justyn M Thomas; C Lad; Antony Galione; A Mark Evans
Adp-ribosyl cyclase and cyclic ADP-ribose hydrolase act as a redox sensor. a primary role for cyclic ADP-ribose in hypoxic pulmonary vasoconstriction.
The Journal of biological chemistry 2001;276(14):11180-8.
2000: Sandip Patel; Grant C Churchill; Antony Galione
Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhance the sensitivity of NAADP receptors for their ligand.
The Biochemical journal 2000;352 Pt 3():725-9.
2000: Grant C Churchill; Antony Galione
Spatial control of Ca2+ signaling by nicotinic acid adenine dinucleotide phosphate diffusion and gradients.
The Journal of biological chemistry 2000;275(49):38687-92.
2000: Sandip Patel; Grant C Churchill; T Sharp; Antony Galione
Widespread distribution of binding sites for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate, in the brain.
The Journal of biological chemistry 2000;275(47):36495-7.
2000: Denis Burdakov; Antony Galione
Two neuropeptides recruit different messenger pathways to evoke Ca2+ signals in the same cell.
Current biology : CB 2000;10(16):993-6.
2000: Antony Galione; Grant C Churchill
Cyclic ADP ribose as a calcium-mobilizing messenger.
Science's STKE : signal transduction knowledge environment 2000;2000(41):pe1.
2000: Antony Galione; Sandip Patel; Grant C Churchill
NAADP-induced calcium release in sea urchin eggs.
Biology of the cell / under the auspices of the European Cell Biology Organization 2000;92(3-4):197-204.
1999: M Reyes-Harde; Barry V L Potter; Antony Galione; Patric Stanton
Induction of hippocampal LTD requires nitric-oxide-stimulated PKG activity and Ca2+ release from cyclic ADP-ribose-sensitive stores.
Journal of neurophysiology 1999;82(3):1569-76.
1999: Y Cui; Antony Galione; Derek A Terrar
Effects of photoreleased cADP-ribose on calcium transients and calcium sparks in myocytes isolated from guinea-pig and rat ventricle.
The Biochemical journal 1999;342 ( Pt 2)():269-73.
1999: Judit Bak; Peter John White; György Timár; L Missiaen; Armando Genazzani; Antony Galione
Nicotinic acid adenine dinucleotide phosphate triggers Ca2+ release from brain microsomes.
Current biology : CB 1999;9(14):751-4.
1999: Rosaria A Cavallaro; L Filocamo; A Galuppi; Antony Galione; M Brufani; Armando Genazzani
Potentiation of cADPR-induced Ca(2+)-release by methylxanthine analogues.
Journal of medicinal chemistry 1999;42(14):2527-34.
1999: Patrick De Smet; Jan B Parys; Sara Vanlingen; Geert Bultynck; Geert Callewaert; Antony Galione; Humbert De Smedt; Ludwig Missiaen
The relative order of IP3 sensitivity of types 1 and 3 IP3 receptors is pH dependent.
Pflügers Archiv : European journal of physiology 1999;438(2):154-8.
1999: Stevan Rakovic; Y Cui; S Iino; Antony Galione; G A Ashamu; Barry V L Potter; Derek A Terrar
An antagonist of cADP-ribose inhibits arrhythmogenic oscillations of intracellular Ca2+ in heart cells.
The Journal of biological chemistry 1999;274(25):17820-7.
1999: M Reyes-Harde; Ruth Empson; Barry V L Potter; Antony Galione; Patric Stanton
Evidence of a role for cyclic ADP-ribose in long-term synaptic depression in hippocampus.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):4061-6.
1999: Jose M Cancela; Grant C Churchill; Antony Galione
Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells.
Nature 1999;398(6722):74-6.
1998: T W Thomas; William R Eckberg; François Dubé; Antony Galione
Mechanisms of calcium release and sequestration in eggs of Chaetopterus pergamentaceus.
Cell calcium 1998;24(4):285-92.
1998: Heather Wilson; Antony Galione
Differential regulation of nicotinic acid-adenine dinucleotide phosphate and cADP-ribose production by cAMP and cGMP.
The Biochemical journal 1998;331 ( Pt 3)():837-43.
1998: Antony Galione; Y Cui; Ruth Empson; S Iino; H Wilson; Derek A Terrar
Cyclic ADP-ribose and the regulation of calcium-induced calcium release in eggs and cardiac myocytes.
Cell biochemistry and biophysics 1998;28(1):19-30.
1997: Antony Galione; Keith T Jones; F Anthony Lai; Karl Swann
A cytosolic sperm protein factor mobilizes Ca2+ from intracellular stores by activating multiple Ca2+ release mechanisms independently of low molecular weight messengers.
The Journal of biological chemistry 1997;272(46):28901-5.
1997: S Iino; Y Cui; Antony Galione; Derek A Terrar
Actions of cADP-ribose and its antagonists on contraction in guinea pig isolated ventricular myocytes. Influence of temperature.
Circulation research 1997;81(5):879-84.
1997: Ruth Empson; Antony Galione
Cyclic ADP-ribose enhances coupling between voltage-gated Ca2+ entry and intracellular Ca2+ release.
The Journal of biological chemistry 1997;272(34):20967-70.
1997: G A Ashamu; Jaswinder Sethi; Antony Galione; Barry V L Potter
Roles for adenosine ribose hydroxyl groups in cyclic adenosine 5'-diphosphate ribose-mediated Ca2+ release.
Biochemistry 1997;36(31):9509-17.
1997: Armando Genazzani; M Mezna; D M Dickey; Francesco Michelangeli; Timothy F Walseth; Antony Galione
Pharmacological properties of the Ca2+-release mechanism sensitive to NAADP in the sea urchin egg.
British journal of pharmacology 1997;121(7):1489-95.
1997: Jaswinder Sethi; Ruth Empson; VC Bailey; Barry V L Potter; Antony Galione
7-Deaza-8-bromo-cyclic ADP-ribose, the first membrane-permeant, hydrolysis-resistant cyclic ADP-ribose antagonist.
The Journal of biological chemistry 1997;272(26):16358-63.
1997: Armando Genazzani; Antony Galione
A Ca2+ release mechanism gated by the novel pyridine nucleotide, NAADP.
Trends in pharmacological sciences 1997;18(4):108-10.
1997: Armando Genazzani; M Mezna; R J Summerhill; Antony Galione; Francesco Michelangeli
Kinetic properties of nicotinic acid adenine dinucleotide phosphate-induced Ca2+ release.
The Journal of biological chemistry 1997;272(12):7669-75.
1997: VC Bailey; Jaswinder Sethi; S M Fortt; Antony Galione; Barry V L Potter
7-Deaza cyclic adenosine 5'-diphosphate ribose: first example of a Ca(2+)-mobilizing partial agonist related to cyclic adenosine 5'-diphosphate ribose.
Chemistry & biology 1997;4(1):51-61.
1996: Jaswinder Sethi; Ruth Empson; Antony Galione
Nicotinamide inhibits cyclic ADP-ribose-mediated calcium signalling in sea urchin eggs.
The Biochemical journal 1996;319 ( Pt 2)():613-7.
1996: S Rakovic; Antony Galione; G A Ashamu; B V Potter; Derek A Terrar
A specific cyclic ADP-ribose antagonist inhibits cardiac excitation-contraction coupling.
Current biology : CB 1996;6(8):989-96.
1996: K T Ault; G Durmowicz; Antony Galione; P L Harger; W B Busa
Modulation of Xenopus embryo mesoderm-specific gene expression and dorsoanterior patterning by receptors that activate the phosphatidylinositol cycle signal transduction pathway.
Development (Cambridge, England) 1996;122(7):2033-41.
1996: Armando Genazzani; J Bak; Antony Galione
Inhibition of cADPR-Hydrolase by ADP-ribose potentiates cADPR synthesis from beta-NAD+.
Biochemical and biophysical research communications 1996;223(3):502-7.
1996: Armando Genazzani; Ruth Empson; Antony Galione
Unique inactivation properties of NAADP-sensitive Ca2+ release.
The Journal of biological chemistry 1996;271(20):11599-602.
1996: N J Willmott; J Asselin; Antony Galione
Calcium store depletion potentiates a phosphodiesterase inhibitor- and dibutyryl cGMP-evoked calcium influx in rat pituitary GH3 cells.
FEBS letters 1996;386(1):39-42.
1996: Armando Genazzani; Antony Galione
Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive pool.
The Biochemical journal 1996;315 ( Pt 3)():721-5.
1996: Amir A Sadighi Akha; N J Willmott; K Brickley; Annette C Dolphin; Antony Galione; S V Hunt
Anti-Ig-induced calcium influx in rat B lymphocytes mediated by cGMP through a dihydropyridine-sensitive channel.
The Journal of biological chemistry 1996;271(13):7297-300.
1996: N Willmott; Jaswinder Sethi; T F Walseth; H C Lee; A M White; Antony Galione
Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway.
The Journal of biological chemistry 1996;271(7):3699-705.
1996: VC Bailey; S M Fortt; R J Summerhill; Antony Galione; B V Potter
Cyclic aristeromycin diphosphate ribose: a potent and poorly hydrolysable Ca(2+)-mobilising mimic of cyclic adenosine diphosphate ribose.
FEBS letters 1996;379(3):227-30.
1995: N J Willmott; Antony Galione; P A Smith
A cADP-ribose antagonist does not inhibit secretagogue-, caffeine- and nitric oxide-induced Ca2+ responses in rat pancreatic beta-cells.
Cell calcium 1995;18(5):411-9.
1995: N J Willmott; Antony Galione; P A Smith
Nitric oxide induces intracellular Ca2+ mobilization and increases secretion of incorporated 5-hydroxytryptamine in rat pancreatic beta-cells.
FEBS letters 1995;371(2):99-104.
1994: Antony Galione; Karl Swann; P Georgiou; Michael Whitaker
Regenerative and non-regenerative calcium transients in hamster eggs triggered by inositol 1,4,5-trisphosphate.
The Journal of physiology 1994;480 ( Pt 3)():465-74.
1994: M A Varney; Antony Galione; Steve P Watson
Lithium-induced decrease in spontaneous Ca2+ oscillations in single GH3 rat pituitary cells.
British journal of pharmacology 1994;112(2):390-5.
1994: Antony Galione
Cyclic ADP-ribose, the ADP-ribosyl cyclase pathway and calcium signalling.
Molecular and cellular endocrinology 1994;98(2):125-31.
1993: R J Summerhill; David G Jackson; Antony Galione
Human lymphocyte antigen CD38 catalyzes the production of cyclic ADP-ribose.
FEBS letters 1993;335(2):231-3.
1993: Antony Galione; A White; N Willmott; Martin Turner; B V Potter; Steve P Watson
cGMP mobilizes intracellular Ca2+ in sea urchin eggs by stimulating cyclic ADP-ribose synthesis.
Nature 1993;365(6445):456-9.
1993: Antony Galione; A McDougall; W B Busa; N Willmott; I Gillot; Michael Whitaker
Redundant mechanisms of calcium-induced calcium release underlying calcium waves during fertilization of sea urchin eggs.
Science (New York, N.Y.) 1993;261(5119):348-52.
1993: A M White; Steve P Watson; Antony Galione
Cyclic ADP-ribose-induced Ca2+ release from rat brain microsomes.
FEBS letters 1993;318(3):259-63.
1993: Antony Galione
Cyclic ADP-ribose: a new way to control calcium.
Science (New York, N.Y.) 1993;259(5093):325-6.
1992: K P Currie; K Swann; Antony Galione; Roderick H Scott
Activation of Ca(2+)-dependent currents in cultured rat dorsal root ganglion neurones by a sperm factor and cyclic ADP-ribose.
Molecular biology of the cell 1992;3(12):1415-25.
1992: Antony Galione
Ca(2+)-induced Ca2+ release and its modulation by cyclic ADP-ribose.
Trends in pharmacological sciences 1992;13(8):304-6.
1991: Antony Galione; H C Lee; W B Busa
Ca(2+)-induced Ca2+ release in sea urchin egg homogenates: modulation by cyclic ADP-ribose.
Science (New York, N.Y.) 1991;253(5024):1143-6.