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Lucrezia Gambardella

Research Profile

Chemicals & Drugs

Anatomy

Procedures

Phenomena

Oxidation-Reduction

Physiology

Disorders

Oxidative Stress

Concepts & Ideas

Membrane Potentials

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Publications

TOP 3
Paola Matarrese; Daniel Remondini; Stefano Salvioli; Enrico Tagliafico; Elena Tenedini; Antonella Tinari; Barbara Ascione; Claudio Franceschi; Lucrezia Gambardella; Walter Malorni
Survival features of EBV-stabilized cells from centenarians: morpho-functional and transcriptomic analyses.
Elisabetta Straface; Isabella Tarissi de Jacobis; Alberto Villani; Marina Viora; Domenico Del Principe; Lucrezia Gambardella; Luciana Giordani; Walter Malorni; Alessandra Marchesi; Alessio Metere; Donatella Pietraforte
Does oxidative stress play a critical role in cardiovascular complications of Kawasaki disease?
Laura Ciarlo; Lucrezia Gambardella; Tina Garofalo; Maria Grasso; Valeria Manganelli; Matteo Marconi; Paola Matarrese; Roberta Misasi; Maurizio Sorice; Antonella Tinari; Walter Malorni
Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease.

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All Publications

2012: Paola Matarrese; Daniel Remondini; Stefano Salvioli; Enrico Tagliafico; Elena Tenedini; Antonella Tinari; Barbara Ascione; Claudio Franceschi; Lucrezia Gambardella; Walter Malorni
Survival features of EBV-stabilized cells from centenarians: morpho-functional and transcriptomic analyses.
Age (Dordrecht, Netherlands) 2012;34(6):1341-59.
2012: Elisabetta Straface; Isabella Tarissi de Jacobis; Alberto Villani; Marina Viora; Domenico Del Principe; Lucrezia Gambardella; Luciana Giordani; Walter Malorni; Alessandra Marchesi; Alessio Metere; Donatella Pietraforte
Does oxidative stress play a critical role in cardiovascular complications of Kawasaki disease?
Antioxidants & redox signaling 2012;17(10):1441-6.
2012: Laura Ciarlo; Lucrezia Gambardella; Tina Garofalo; Maria Grasso; Valeria Manganelli; Matteo Marconi; Paola Matarrese; Roberta Misasi; Maurizio Sorice; Antonella Tinari; Walter Malorni
Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease.
Journal of lipid research 2012;53(10):2057-68.
2012: Anna Maria Giammarioli; Lucio Gnessi; Roger J Griffin; Manuela Alberton; Cristiana Barbati; Lucrezia Gambardella; Maurizio Minetti; Donatella Pietraforte; Antonella Tinari; Walter Malorni
Differential effects of the glycolysis inhibitor 2-deoxy-D-glucose on the activity of pro-apoptotic agents in metastatic melanoma cells, and induction of a cytoprotective autophagic response.
International journal of cancer. Journal international du cancer 2012;131(4):E337-47.
2012: Antonella Capozzi; Lucrezia Gambardella; Walter Malorni; Clementina Manera; Elisabetta Mantuano; Paola Matarrese; Vincenzo Mattei; Giuseppe Saccomanni; Maurizio Sorice; Roberta Misasi
A new 4-phenyl-1,8-naphthyridine derivative affects carcinoma cell proliferation by impairing cell cycle progression and inducing apoptosis.
Anti-cancer agents in medicinal chemistry 2012;12(6):653-62.
2012: Brigitta Buttari; Raffaele Capoano; Barbara Cuccu; Lucrezia Gambardella; Igino Genuini; Walter Malorni; Elisabetta Profumo; Bruno Salvati; Elisabetta Straface; Rachele Riganò
Erythrocytes from patients with carotid atherosclerosis fail to control dendritic cell maturation.
International journal of cardiology 2012;155(3):484-6.
2012: Maurizio Sorice; Vincenzo Tasciotti; Antonella Tinari; Laura Ciarlo; Lucrezia Gambardella; Tina Garofalo; Valeria Manganelli; Paola Matarrese; Vincenzo Mattei; Roberta Misasi; Walter Malorni
Dynamics of mitochondrial raft-like microdomains in cell life and death.
Communicative & integrative biology 2012;5(2):217-9.
2012: Elisabetta Straface; Marta Brandani; Lucrezia Gambardella; Walter Malorni
Sex differences at cellular level: "cells have a sex".
Handbook of experimental pharmacology 2012;(214):49-65.
2012: Cristiana Barbati; Lucrezia Gambardella; Richard H Karas; Fiorella Malchiodi-Albedi; Walter Malorni; Marina Pierdominici; Giuseppe Rosano; Elena Ortona
Cell surface estrogen receptor alpha is upregulated during subchronic metabolic stress and inhibits neuronal cell degeneration.
PloS one 2012;7(7):e42339.
2012: Antonello Giovannetti; Walter Malorni; Donatella Pietraforte; Edoardo Rosato; FELICE SALSANO; Lucrezia Gambardella; Anna Maria Giammarioli; Elisabetta Straface
Red blood cell alterations in systemic sclerosis: a pilot study.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012;30(2):418-27.
2011: Elisabetta Profumo; Bruno Salvati; Elisabetta Straface; Brigitta Buttari; Raffaele Capoano; Lucrezia Gambardella; Igino Genuini; Walter Malorni; Linda Petrone; Donatella Pietraforte; Rachele Riganò
Redox imbalance of red blood cells impacts T lymphocyte homeostasis: implication in carotid atherosclerosis.
Thrombosis and haemostasis 2011;106(6):1117-26.
2011: Vincenzo Mattei; Roberta Misasi; Vincenzo Tasciotti; Antonella Tinari; Laura Ciarlo; Lucrezia Gambardella; Tina Garofalo; Walter Malorni; Valeria Manganelli; Paola Matarrese; Maurizio Sorice
Recruitment of cellular prion protein to mitochondrial raft-like microdomains contributes to apoptosis execution.
Molecular biology of the cell 2011;22(24):4842-53.
2011: Paola Matarrese; Lucia Nencioni; Rossella Sgarbanti; Barbara Ascione; Paola Checconi; Laura Ciarlo; Lucrezia Gambardella; Enrico Garaci; Walter Malorni; Anna Teresa Palamara
Pepstatin A alters host cell autophagic machinery and leads to a decrease in influenza A virus production.
Journal of cellular physiology 2011;226(12):3368-77.
2011: Elisabetta Straface; Antonella Mattatelli; Luciano Agati; Francesca Boccalini; Emanuele Canali; Lucrezia Gambardella; Walter Malorni
The red blood cell as a gender-associated biomarker in metabolic syndrome: a pilot study.
International journal of cell biology 2011;2011():204157.
2010: Elisabetta Straface; Pasquale Lista; Lucrezia Gambardella; Flavia Franconi; Walter Malorni
Gender-specific features of plasmatic and circulating cell alterations as risk factors in cardiovascular disease.
Fundamental & clinical pharmacology 2010;24(6):665-74.
2010: Antonello Giovannetti; Edoardo Rosato; Cristina Renzi; AM Maselli; Lucrezia Gambardella; Anna Maria Giammarioli; Paolo Palange; Patrizia Paoletti; Simonetta Pisarri; FELICE SALSANO; Walter Malorni; Marina Pierdominici
Analyses of T cell phenotype and function reveal an altered T cell homeostasis in systemic sclerosis. Correlations with disease severity and phenotypes.
Clinical immunology (Orlando, Fla.) 2010;137(1):122-33.
2010: Elisabetta Straface; Lucrezia Gambardella; Alessio Metere; Alessandra Marchesi; Giuseppe Palumbo; Elisabetta Cortis; Alberto Villani; Donatella Pietraforte; Marina Viora; Walter Malorni; Domenico Del Principe
Oxidative stress and defective platelet apoptosis in naïve patients with Kawasaki disease.
Biochemical and biophysical research communications 2010;392(3):426-30.
2009: Elisabetta Straface; Rosa Vona; Lucrezia Gambardella; Barbara Ascione; Maria Marino; Paola Bulzomi; Silvia Canu; Rita Coinu; Giuseppe Rosano; Walter Malorni; Flavia Franconi
Cell sex determines anoikis resistance in vascular smooth muscle cells.
FEBS letters 2009;583(21):3448-54.
2009: Anna M Giammarioli; Rosa Vona; Lucrezia Gambardella; Barbara Ascione; Angela Maselli; Cristiana Barbati; Antonella Tinari; Walter Malorni
Interferon-gamma bolsters CD95/Fas-mediated apoptosis of astroglioma cells.
The FEBS journal 2009;276(20):5920-35.
2009: Paola Matarrese; Elisabetta Straface; Giuseppe Palumbo; Maurizio Anselmi; Lucrezia Gambardella; Barbara Ascione; Domenico Del Principe; Walter Malorni
Mitochondria regulate platelet metamorphosis induced by opsonized zymosan A--activation and long-term commitment to cell death.
The FEBS journal 2009;276(3):845-56.
2008: Paola Matarrese; Valeria Manganelli; Tina Garofalo; Antonella Tinari; Lucrezia Gambardella; Kenneth Ndebele; Roya Khosravi-Far; Maurizio Sorice; Mauro Degli Esposti; Walter Malorni
Endosomal compartment contributes to the propagation of CD95/Fas-mediated signals in type II cells.
The Biochemical journal 2008;413(3):467-78.
2008: Anna Maria Giammarioli; Angela Maselli; Andrea Casagrande; Lucrezia Gambardella; Angelo Gallina; Massimo Spada; Antonello Giovannetti; Enrico Proietti; Walter Malorni; Marina Pierdominici
Pyrimethamine induces apoptosis of melanoma cells via a caspase and cathepsin double-edged mechanism.
Cancer research 2008;68(13):5291-300.
2007: Paola Matarrese; Loredana Falzano; Alessia Fabbri; Lucrezia Gambardella; Claudio Frank; Blandine Geny; Michel R Popoff; Walter Malorni; Carla Fiorentini
Clostridium difficile toxin B causes apoptosis in epithelial cells by thrilling mitochondria. Involvement of ATP-sensitive mitochondrial potassium channels.
The Journal of biological chemistry 2007;282(12):9029-41.
2007: Donatella Pietraforte; Paola Matarrese; Elisabetta Straface; Lucrezia Gambardella; Alessio Metere; Giuseppe Scorza; Thomas L Leto; Walter Malorni; Maurizio Minetti
Two different pathways are involved in peroxynitrite-induced senescence and apoptosis of human erythrocytes.
Free radical biology & medicine 2007;42(2):202-14.
2006: Gabriele Lucantoni; Donatella Pietraforte; Paola Matarrese; Lucrezia Gambardella; Alessio Metere; Gregorino Paone; Enrico Li Bianchi; Elisabetta Straface
The red blood cell as a biosensor for monitoring oxidative imbalance in chronic obstructive pulmonary disease: an ex vivo and in vitro study.
Antioxidants & redox signaling 2006;8(7-8):1171-82.
2006: Anna Maria Giammarioli; Lucrezia Gambardella; Maria Giovanna Quaranta; Caterina Lapenta; Stefano M Santini; Filippo Belardelli; Marina Viora; Walter Malorni
Differentiation of monocyte-derived dendritic cells is associated with upregulation and activation of Rac-1 small GTPase.
FEBS letters 2006;580(13):3335-9.
2005: Marina Pierdominici; Anna Maria Giammarioli; Lucrezia Gambardella; Marco De Felice; Isabella Quinti; Metello Iacobini; Maurizio Carbonari; Walter Malorni; Antonello Giovannetti
Pyrimethamine (2,4-diamino-5-p-chlorophenyl-6-ethylpyrimidine) induces apoptosis of freshly isolated human T lymphocytes, bypassing CD95/Fas molecule but involving its intrinsic pathway.
The Journal of pharmacology and experimental therapeutics 2005;315(3):1046-57.
2005: Tina Garofalo; Anna Maria Giammarioli; Roberta Misasi; Antonella Tinari; Valeria Manganelli; Lucrezia Gambardella; Antonio Pavan; Walter Malorni; Maurizio Sorice
Lipid microdomains contribute to apoptosis-associated modifications of mitochondria in T cells.
Cell death and differentiation 2005;12(11):1378-89.
2005: Elisabetta Straface; Paola Matarrese; Lucrezia Gambardella; Rosa Vona; Antonio Sgadari; Maria Caterina Silveri; Walter Malorni
Oxidative imbalance and cathepsin D changes as peripheral blood biomarkers of Alzheimer disease: a pilot study.
FEBS letters 2005;579(13):2759-66.
2005: Paola Matarrese; Elisabetta Straface; Donatella Pietraforte; Lucrezia Gambardella; Rosa Vona; Alessandro Maccaglia; Maurizio Minetti; Walter Malorni
Peroxynitrite induces senescence and apoptosis of red blood cells through the activation of aspartyl and cysteinyl proteases.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):416-8.
2005: Paola Matarrese; Antonella Tinari; Lucrezia Gambardella; Elisabetta Mormone; Piero Narilli; Marina Pierdominici; Roberto Cauda; Walter Malorni
HIV protease inhibitors prevent mitochondrial hyperpolarization and redox imbalance and decrease endogenous uncoupler protein-2 expression in gp 120-activated human T lymphocytes.
Antiviral therapy 2005;10 Suppl 2():M29-45.
2003: Paola Matarrese; Lucrezia Gambardella; Antonio Cassone; STEFANO VELLA; Roberto Cauda; Walter Malorni
Mitochondrial membrane hyperpolarization hijacks activated T lymphocytes toward the apoptotic-prone phenotype: homeostatic mechanisms of HIV protease inhibitors.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(12):6006-15.
2001: Anna Maria Giammarioli; Tina Garofalo; Maurizio Sorice; Roberta Misasi; Lucrezia Gambardella; Roberto Gradini; Stefano Fais; Antonio Pavan; Walter Malorni
GD3 glycosphingolipid contributes to Fas-mediated apoptosis via association with ezrin cytoskeletal protein.
FEBS letters 2001;506(1):45-50.
2001: Paola Matarrese; Ugo Testa; Roberto Cauda; STEFANO VELLA; Lucrezia Gambardella; Walter Malorni
Expression of P-170 glycoprotein sensitizes lymphoblastoid CEM cells to mitochondria-mediated apoptosis.
The Biochemical journal 2001;355(Pt 3):587-95.
2000: Elisabetta Straface; Paola Matarrese; Lucrezia Gambardella; S Forte; S Carlone; E Libianchi; G Schmid; Walter Malorni
N-Acetylcysteine counteracts erythrocyte alterations occurring in chronic obstructive pulmonary disease.
Biochemical and biophysical research communications 2000;279(2):552-6.