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Dinorah Gambino

Research Profile

Chemicals & Drugs

Procedures

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Publications

TOP 3
Bruno Demoro; Dinorah Gambino; Julia Lorenzo; Fernanda Marques; Cristina P Matos; Virtudes Moreno; Lucía Otero; Alejandra Rodríguez; Isabel Santos; João Costa Pessoa; Rodrigo F M de Almeida; Ana Isabel Tomaz
Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding mechanism.
Julio Benítez; Aline Cavalcanti de Queiroz; Hugo Cerecetto; Isabel Correia; Mercedes González; Luís Maurício T R Lima; Virtudes Moreno; João Costa Pessoa; Javier Varela; Magna S Alexandre-Moreira; Marina Amaral Alves; Eliezer J Barreiro; Dinorah Gambino
New oxidovanadium(IV) N-acylhydrazone complexes: promising antileishmanial and antitrypanosomal agents.
Ignacio E León; Dinorah Gambino; Gabriel Arrambide; Daniel A Barrio; Ana L Di Virgilio; Susana B Etcheverry
Hydroxylamido-amino acid complexes of oxovanadium(V). Toxicological study in cell culture and in a zebrafish model.

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All Publications

2013: Bruno Demoro; Dinorah Gambino; Julia Lorenzo; Fernanda Marques; Cristina P Matos; Virtudes Moreno; Lucía Otero; Alejandra Rodríguez; Isabel Santos; João Costa Pessoa; Rodrigo F M de Almeida; Ana Isabel Tomaz
Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding mechanism.
Dalton transactions (Cambridge, England : 2003) 2013;42(19):7131-46.
2013: Julio Benítez; Aline Cavalcanti de Queiroz; Hugo Cerecetto; Isabel Correia; Mercedes González; Luís Maurício T R Lima; Virtudes Moreno; João Costa Pessoa; Javier Varela; Magna S Alexandre-Moreira; Marina Amaral Alves; Eliezer J Barreiro; Dinorah Gambino
New oxidovanadium(IV) N-acylhydrazone complexes: promising antileishmanial and antitrypanosomal agents.
European journal of medicinal chemistry 2013;62():20-7.
2012: Ignacio E León; Dinorah Gambino; Gabriel Arrambide; Daniel A Barrio; Ana L Di Virgilio; Susana B Etcheverry
Hydroxylamido-amino acid complexes of oxovanadium(V). Toxicological study in cell culture and in a zebrafish model.
Metallomics : integrated biometal science 2012;4(12):1287-96.
2012: Diego Santos; Javier Varela; Diego Benítez; María E Caputto; Francesco Caruso; Hugo Cerecetto; Liliana M Finkielsztein; Natalia Gómez; Mercedes González; Albertina G Moglioni; Graciela Y Moltrasio; Beatriz Parajón-Costa; Miriam Rossi; Dinorah Gambino
Activity on Trypanosoma cruzi, erythrocytes lysis and biologically relevant physicochemical properties of Pd(II) and Pt(II) complexes of thiosemicarbazones derived from 1-indanones.
Journal of inorganic biochemistry 2012;117():270-6.
2012: Bruno Demoro; Roberto Docampo; Ricardo Faccio; Melina Galizzi; Dinorah Gambino; Mercedes González; Leena Malayil; Alvaro W Mombrú; Diego Benítez; Francesco Caruso; Hugo Cerecetto; Miriam Rossi; Lucía Otero
Bisphosphonate metal complexes as selective inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
Dalton transactions (Cambridge, England : 2003) 2012;41(21):6468-76.
2012: Lorena Becco; María Elena Bravo; Beatriz Garat; Virtudes Moreno; María José Prieto; Alejandra Rodríguez; Lena Ruiz-Azuara; Dinorah Gambino
New achievements on biological aspects of copper complexes Casiopeínas®: interaction with DNA and proteins and anti-Trypanosoma cruzi activity.
Journal of inorganic biochemistry 2012;109():49-56.
2011: Marisol Vieites; Francielle Luane Fischer; Beatriz Garat; Virtudes Moreno; Lucía Otero; Mariana Pagano; María José Prieto; Pablo Smircich; Hernán Terenzi; Dinorah Gambino
DNA as molecular target of analogous palladium and platinum anti-Trypanosoma cruzi compounds: a comparative study.
Journal of inorganic biochemistry 2011;105(12):1704-11.
2011: Fernando R Pavan; Gustavo V Poelhsitz; Leticia S Sato; Sergio R A Leite; Virtudes Moreno; Marilia I F Barbosa; Alzir A Batista; Javier Ellena; Scott Franzblau; Dinorah Gambino; Clarice Queico Fujimura Leite
Ruthenium(II) phosphine/diimine/picolinate complexes: inorganic compounds as agents against tuberculosis.
European journal of medicinal chemistry 2011;46(10):5099-107.
2011: Natalia Gómez; Albertina Moglioni; Alvaro Mombrú; Diego Santos; Carina Shayo; Leopoldo Suescun; Ramiro Vázquez; Monica Vermeulen; Liliana Finkielsztein; Dinorah Gambino; Carlos Davio
Synthesis, structural characterization, and pro-apoptotic activity of 1-indanone thiosemicarbazone platinum(II) and palladium(II) complexes: potential as antileukemic agents.
ChemMedChem 2011;6(8):1485-94.
2011: Alicia Merlino; Lucía Otero; Dinorah Gambino; E Laura Coitiño
In search of patterns over physicochemical properties and pharmacological activities for a set of [MCl₂(thiosemicarbazone)] complexes (M=Pt/Pd): support for multiple mechanisms of antichagasic action excluding DNA-bonding in vivo?
European journal of medicinal chemistry 2011;46(7):2639-51.
2011: Julio Benítez; Lorena Becco; Isabel Correia; Sandra Milena Leal; Helena Guiset; João Costa Pessoa; Julia Lorenzo; Sebastian Tanco; Patricia Escobar; Virtudes Moreno; Beatriz Garat; Dinorah Gambino
Vanadium polypyridyl compounds as potential antiparasitic and antitumoral agents: new achievements.
Journal of inorganic biochemistry 2011;105(2):303-12.
2010: Maribel Navarro; Chiara Gabbiani; Luigi Messori; Dinorah Gambino
Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives.
Drug discovery today 2010;15(23-24):1070-8.
2010: Bruno Demoro; Francesco Caruso; Miriam Rossi; Diego Benítez; Mercedes Gonzalez; Hugo Cerecetto; Beatriz Parajón-Costa; Jorge Castiglioni; Melina Galizzi; Roberto Docampo; Lucía Otero; Dinorah Gambino
Risedronate metal complexes potentially active against Chagas disease.
Journal of inorganic biochemistry 2010;104(12):1252-8.
2010: M Belén Tarallo; Carolina Urquiola; Antonio Monge; Beatriz Parajón Costa; Ronny R Ribeiro; Antonio J Costa-Filho; Roberto C Mercader; Fernando R Pavan; Clarice Queico Fujimura Leite; María H Torre; Dinorah Gambino
Design of novel iron compounds as potential therapeutic agents against tuberculosis.
Journal of inorganic biochemistry 2010;104(11):1164-70.
2010: Gabriel Arrambide; Daniel A Barrio; Susana B Etcheverry; Dinorah Gambino; Enrique J Baran
Spectroscopic behavior and biological activity of K2[VO(O2)NTA].2H2O.
Biological trace element research 2010;136(2):241-8.
2010: Dinorah Gambino
Advances and current perspectives in medicinal inorganic chemistry.
Current medicinal chemistry 2010;17(31):3605.
2010: Dinorah Gambino
Potential therapeutic applications of metal compounds directed towards hypoxic tissues.
Current medicinal chemistry 2010;17(31):3616-31.
2009: Mariana Pagano; Bruno Demoro; Jeanette Toloza; Lucía Boiani; Mercedes González; Hugo Cerecetto; Claudio Olea-Azar; Ester Norambuena; Dinorah Gambino; Lucía Otero
Effect of ruthenium complexation on trypanocidal activity of 5-nitrofuryl containing thiosemicarbazones.
European journal of medicinal chemistry 2009;44(12):4937-43.
2009: Julio Benítez; Lucía Guggeri; Isabel Tomaz; João Costa Pessoa; Virtudes Moreno; Julia Lorenzo; Francesc X Avilés; Beatriz Garat; Dinorah Gambino
A novel vanadyl complex with a polypyridyl DNA intercalator as ligand: a potential anti-protozoa and anti-tumor agent.
Journal of inorganic biochemistry 2009;103(10):1386-94.
2009: Marisol Vieites; Pablo Smircich; Lucía Guggeri; Edgar Marchán; Alicia Gómez-Barrio; Maribel Navarro; Beatriz Garat; Dinorah Gambino
Synthesis and characterization of a pyridine-2-thiol N-oxide gold(I) complex with potent antiproliferative effect against Trypanosoma cruzi and Leishmania sp. insight into its mechanism of action.
Journal of inorganic biochemistry 2009;103(10):1300-6.
2009: Josefina Rivadeneira; Daniel A Barrio; Gabriel Arrambide; Dinorah Gambino; Liliana Bruzzone; Susana B Etcheverry
Biological effects of a complex of vanadium(V) with salicylaldehyde semicarbazone in osteoblasts in culture: mechanism of action.
Journal of inorganic biochemistry 2009;103(4):633-42.
2009: Julio Benítez; Lucía Guggeri; Isabel Tomaz; Gabriel Arrambide; Maribel Navarro; João Costa Pessoa; Beatriz Garat; Dinorah Gambino
Design of vanadium mixed-ligand complexes as potential anti-protozoa agents.
Journal of inorganic biochemistry 2009;103(4):609-16.
2009: Marisol Vieites; Lucía Otero; Diego Santos; Claudio Olea-Azar; Ester Norambuena; Gabriela Aguirre; Hugo Cerecetto; Mercedes González; Ulrike Kemmerling; Antonio Morello; Juan Diego Maya; Dinorah Gambino
Platinum-based complexes of bioactive 3-(5-nitrofuryl)acroleine thiosemicarbazones showing anti-Trypanosoma cruzi activity.
Journal of inorganic biochemistry 2009;103(3):411-8.
2009: Carolina Urquiola; Marisol Vieites; María H Torre; Mauricio Cabrera; María Laura Lavaggi; Hugo Cerecetto; Mercedes González; Adela López de Cerain; Antonio Monge; Pablo Smircich; Beatriz Garat; Dinorah Gambino
Cytotoxic palladium complexes of bioreductive quinoxaline N1,N4-dioxide prodrugs.
Bioorganic & medicinal chemistry 2009;17(4):1623-9.
2008: Lucía Otero; Christian Folch; Germán Barriga; Carolina Rigol; Lucia Opazo; Marisol Vieites; Dinorah Gambino; Hugo Cerecetto; Ester Norambuena; Claudio Olea-Azar
ESR, electrochemical and reactivity studies of antitrypanosomal palladium thiosemicarbazone complexes.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2008;70(3):519-23.
2008: Marisol Vieites; Pablo Smircich; Beatriz Parajón-Costa; Jorge Rodríguez; Verónica Galaz; Claudio Olea-Azar; Lucía Otero; Gabriela Aguirre; Hugo Cerecetto; Mercedes González; Alicia Gómez-Barrio; Beatriz Garat; Dinorah Gambino
Potent in vitro anti-Trypanosoma cruzi activity of pyridine-2-thiol N-oxide metal complexes having an inhibitory effect on parasite-specific fumarate reductase.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2008;13(5):723-35.
2008: Marisol Vieites; Lucía Otero; Diego Santos; Jeannette Toloza; Roberto Figueroa; Ester Norambuena; Claudio Olea-Azar; Gabriela Aguirre; Hugo Cerecetto; Mercedes González; Antonio Morello; Juan Diego Maya; Beatriz Garat; Dinorah Gambino
Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents.
Journal of inorganic biochemistry 2008;102(5-6):1033-43.
2008: Lucía Otero; Juan Diego Maya; Antonio Morello; Carolina Rigol; G Barriga; J Rodríguez; C Folch; Ester Norambuena; Mercedes González; C Olea Azar; Hugo Cerecetto; Dinorah Gambino
Insight into the bioreductive mode of action of antitrypanosomal 5-nitrofuryl containing thiosemicarbazones.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2008;4(1):11-7.
2008: Carolina Urquiola; Dinorah Gambino; Mauricio Cabrera; María Laura Lavaggi; Hugo Cerecetto; Mercedes González; Adela López de Cerain; Antonio Monge; Antonio J Costa-Filho; María H Torre
New copper-based complexes with quinoxaline N1,N4-dioxide derivatives, potential antitumoral agents.
Journal of inorganic biochemistry 2008;102(1):119-26.
2007: Dinorah Gambino; Lucía Otero; Marisol Vieites; Mariana Boiani; Mercedes González; Enrique J Baran; Hugo Cerecetto
Vibrational spectra of palladium 5-nitrofuryl thiosemicarbazone complexes: experimental and theoretical study.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2007;68(2):341-8.
2007: Lucía Otero; Pablo Smircich; Marisol Vieites; Martin Ciganda; Patricia Cardoso Severino; Hernán Terenzi; Hugo Cerecetto; Dinorah Gambino; Beatriz Garat
DNA conformational changes and cleavage by ruthenium(II) nitrofurylsemicarbazone complexes.
Journal of inorganic biochemistry 2007;101(1):74-9.
2006: Lucía Otero; Gabriela Aguirre; Lucía Boiani; Ana Denicola; Carolina Rigol; Claudio Olea-Azar; Juan Diego Maya; Antonio Morello; Mercedes González; Dinorah Gambino; Hugo Cerecetto
Nitrofurylsemicarbazone rhenium and ruthenium complexes as anti-trypanosomal agents.
European journal of medicinal chemistry 2006;41(11):1231-9.
2006: Carolina Urquiola; Marisol Vieites; Gabriela Aguirre; Adoración Marín; Beatriz Solano; Gabriel Arrambide; Pabla Noblía; María Laura Lavaggi; María H Torre; Mercedes González; Antonio Monge; Dinorah Gambino; Hugo Cerecetto
Improving anti-trypanosomal activity of 3-aminoquinoxaline-2-carbonitrile N1,N4-dioxide derivatives by complexation with vanadium.
Bioorganic & medicinal chemistry 2006;14(16):5503-9.
2006: Marisol Vieites; Pabla Noblía; María H Torre; Hugo Cerecetto; María Laura Lavaggi; Antonio J Costa-Filho; Amaia Azqueta; Adela López de Cerain; Antonio Monge; Beatriz Parajón-Costa; Mercedes González; Dinorah Gambino
Selective hypoxia-cytotoxins based on vanadyl complexes with 3-aminoquinoxaline-2-carbonitrile-N1,N4-dioxide derivatives.
Journal of inorganic biochemistry 2006;100(8):1358-67.
2006: Lucía Otero; Marisol Vieites; Lucía Boiani; Ana Denicola; Carolina Rigol; Lucía Opazo; Claudio Olea-Azar; Juan Diego Maya; Antonio Morello; R Luise Krauth-Siegel; Oscar E Piro; Eduardo E Castellano; Mercedes González; Dinorah Gambino; Hugo Cerecetto
Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets.
Journal of medicinal chemistry 2006;49(11):3322-31.
2006: Pabla Noblía; Marisol Vieites; María H Torre; Antonio J Costa-Filho; Hugo Cerecetto; Mercedes González; María Laura Lavaggi; Yusuke Adachi; Hiromu Sakurai; Dinorah Gambino
Novel vanadyl complexes with quinoxaline N(1),N(4)-dioxide derivatives as potent in vitro insulin-mimetic compounds.
Journal of inorganic biochemistry 2006;100(2):281-7.
2005: Carolina Rigol; Claudio Olea-Azar; Fernando Mendizábal; Lucía Otero; Dinorah Gambino; Mercedes González; Hugo Cerecetto
Electrochemical and ESR study of 5-nitrofuryl-containing thiosemicarbazones antiprotozoal drugs.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2005;61(13-14):2933-8.
2005: María H Torre; Dinorah Gambino; Jeannette Araujo; Hugo Cerecetto; Mercedes González; María Laura Lavaggi; Amaia Azqueta; Adela López de Cerain; Antonio Monge Vega; Ulrich Abram; Antonio J Costa-Filho
Novel Cu(II) quinoxaline N1,N4-dioxide complexes as selective hypoxic cytotoxins.
European journal of medicinal chemistry 2005;40(5):473-80.
2005: Anayive P Rebolledo; Marisol Vieites; Dinorah Gambino; Oscar E Piro; Eduardo E Castellano; Carlos Zani; Elaine M Souza-Fagundes; Letícia R Teixeira; Alzir A Batista; Heloisa Beraldo
Palladium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones: spectral characterization, structural studies and cytotoxic activity.
Journal of inorganic biochemistry 2005;99(3):698-706.
2005: Pabla Noblía; Marisol Vieites; Beatriz Parajón-Costa; Enrique J Baran; Hugo Cerecetto; Patricia Draper; Mercedes González; Oscar E Piro; Eduardo E Castellano; Amaia Azqueta; Adela López de Ceráin; Antonio Monge-Vega; Dinorah Gambino
Vanadium(V) complexes with salicylaldehyde semicarbazone derivatives bearing in vitro anti-tumor activity toward kidney tumor cells (TK-10): crystal structure of [VVO2(5-bromosalicylaldehyde semicarbazone)].
Journal of inorganic biochemistry 2005;99(2):443-51.
2004: Gabriela Aguirre; Lucía Boiani; Hugo Cerecetto; Marcelo Fernández; Mercedes González; Ana Denicola; Lucía Otero; Dinorah Gambino; Carolina Rigol; Claudio Olea-Azar; Mario Faundez
In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones.
Bioorganic & medicinal chemistry 2004;12(18):4885-93.
2004: Eliana Cabrera; Hugo Cerecetto; Mercedes González; Dinorah Gambino; Pabla Noblia; Lucía Otero; Beatriz Parajón-Costa; Atilio Anzellotti; Roberto A Sánchez-Delgado; Amaia Azqueta; Adela López de Ceráin; Antonio Monge
Ruthenium (II) nitrofurylsemicarbazone complexes: new DNA binding agents.
European journal of medicinal chemistry 2004;39(4):377-82.
2004: Heloisa Beraldo; Dinorah Gambino
The wide pharmacological versatility of semicarbazones, thiosemicarba-zones and their metal complexes.
Mini reviews in medicinal chemistry 2004;4(1):31-9.
2002: Dinorah Gambino; Eduardo Kremer; Enrique J Baran
Infrared spectra of new Re(III) complexes with thiourea derivatives.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2002;58(14):3085-92.