Robin Ganellin

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Concepts & Ideas

Structure-Activity Relationship

Anatomy

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Levoin Nicolas; Calmels Thierry; Poupardin-Olivier Olivia; Labeeuw Olivier; Danvy Denis; Robert Philippe; Berrebi-Bertrand Isabelle; Ganellin C Robin; Schunack Walter; Stark Holger; Capet Marc
Refined docking as a valuable tool for lead optimization: application to histamine H3 receptor antagonists.
da Silva Joaquim Fernando Mendes; Walters Marcus; Al-Damluji Saad; Ganellin C Robin
Molecular features of the prazosin molecule required for activation of Transport-P.
Das Bhaskar C; Madhukumar Ankanahlli V; Anguiano Jaime; Kim Sean; Sinz Michael; Zvyaga Tatyana A; Power Eoin C; Ganellin C Robin; Mani Sridhar
Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR).

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Robin Ganellin (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2008: Levoin Nicolas; Calmels Thierry; Poupardin-Olivier Olivia; Labeeuw Olivier; Danvy Denis; Robert Philippe; Berrebi-Bertrand Isabelle; Ganellin C Robin; Schunack Walter; Stark Holger; Capet Marc
Refined docking as a valuable tool for lead optimization: application to histamine H3 receptor antagonists.
Archiv der Pharmazie 2008;341(10):610-23.
2008: da Silva Joaquim Fernando Mendes; Walters Marcus; Al-Damluji Saad; Ganellin C Robin
Molecular features of the prazosin molecule required for activation of Transport-P.
Bioorganic & medicinal chemistry 2008;16(15):7254-63.
2008: Das Bhaskar C; Madhukumar Ankanahlli V; Anguiano Jaime; Kim Sean; Sinz Michael; Zvyaga Tatyana A; Power Eoin C; Ganellin C Robin; Mani Sridhar
Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR).
Bioorganic & medicinal chemistry letters 2008;18(14):3974-7.
2007: Fletcher David I; Ganellin C Robin; Piergentili Alessandro; Dunn Philip M; Jenkinson Donald H
Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SK(Ca)).
Bioorganic & medicinal chemistry 2007;15(16):5457-79.
2007: Ligneau X; Perrin D; Landais L; Camelin J-C; Calmels T P G; Berrebi-Bertrand I; Lecomte J-M; Parmentier R; Anaclet C; Lin J-S; Bertaina-Anglade V; la Rochelle C Drieu; d'Aniello F; Rouleau A; Gbahou F; Arrang J-M; Ganellin C R; Stark H; Schunack W; Schwartz J-C
BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical pharmacology.
The Journal of pharmacology and experimental therapeutics 2007;320(1):365-75.
2006: Shah Mala M; Javadzadeh-Tabatabaie Mazyar; Benton David C H; Ganellin C Robin; Haylett Dennis G
Enhancement of hippocampal pyramidal cell excitability by the novel selective slow-afterhyperpolarization channel blocker 3-(triphenylmethylaminomethyl)pyridine (UCL2077).
Molecular pharmacology 2006;70(5):1494-502.
2006: Power Eoin C; Ganellin C Robin; Benton David C H
Partial structures of ketoconazole as modulators of the large conductance calcium-activated potassium channel (BK(Ca)).
Bioorganic & medicinal chemistry letters 2006;16(4):887-90.
2006: Parsons Mike E; Ganellin C Robin
Histamine and its receptors.
British journal of pharmacology 2006;147 Suppl 1():S127-35.
2005: Ganellin C Robin; Bishop Paul B; Bambal Ramesh B; Chan Suzanne M T; Leblond Bertrand; Moore Andrew N J; Zhao Lihua; Bourgeat Pierre; Rose Christiane; Vargas Froylan; Schwartz Jean-Charles
Inhibitors of tripeptidyl peptidase II. 3. Derivation of butabindide by successive structure optimizations leading to a potential general approach to designing exopeptidase inhibitors.
Journal of medicinal chemistry 2005;48(23):7333-42.
2005: Zunszain Patricia A; Federico Cesare; Sechi Mario; Al-Damluji Saad; Ganellin C Robin
Search for the pharmacophore in prazosin for Transport-P.
Bioorganic & medicinal chemistry 2005;13(11):3681-9.
2005: Apelt J; Grassmann S; Ligneau X; Pertz H H; Ganellin C R; Arrang J M; Schwartz J C; Schunack W; Stark H
Search for histamine H3 receptor antagonists with combined inhibitory potency at Ntau-methyltransferase: ether derivatives.
Die Pharmazie 2005;60(2):97-106.
2004: Grassmann Sven; Apelt Joachim; Ligneau Xavier; Pertz Heinz H; Arrang Jean-Michel; Ganellin C Robin; Schwartz Jean-Charles; Schunack Walter; Stark Holger
Search for histamine H(3) receptor ligands with combined inhibitory potency at histamine N-methyltransferase: omega-piperidinoalkanamine derivatives.
Archiv der Pharmazie 2004;337(10):533-45.
2004: Galanakis Dimitrios; Ganellin C Robin; Chen Jian-Quing; Gunasekera Diyan; Dunn Philip M
Bis-quinolinium cyclophanes: toward a pharmacophore model for the blockade of apamin-sensitive SKCa channels in sympathetic neurons.
Bioorganic & medicinal chemistry letters 2004;14(16):4231-5.
2004: Galanakis Dimitrios; Ganellin C Robin
Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry.
Bioorganic & medicinal chemistry letters 2004;14(15):4031-5.
2004: Pelloux-Léon Nadia; Fkyerat Abdellatif; Piripitsi Antonia; Tertiuk Wasyl; Schunack Walter; Stark Holger; Garbarg Monique; Ligneau Xavier; Arrang Jean-Michel; Schwartz Jean-Charles; Ganellin C Robin
Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.
Journal of medicinal chemistry 2004;47(12):3264-74.
2004: Meier Galina; Krause Michael; Hüls Annette; Ligneau Xavier; Pertz Heinz H; Arrang Jean-Michel; Ganellin C Robin; Schwartz Jean-Charles; Schunack Walter; Stark Holger
4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.
Journal of medicinal chemistry 2004;47(10):2678-87.
2004: Mikó Tibor; Ligneau Xavier; Pertz Heinz H; Arrang Jean-Michel; Ganellin C Robin; Schwartz Jean-Charles; Schunack Walter; Stark Holger
Structural variations of 1-(4-(phenoxymethyl)benzyl)piperidines as nonimidazole histamine H3 receptor antagonists.
Bioorganic & medicinal chemistry 2004;12(10):2727-36.
2004: Dougalis Antonios; Lees George; Ganellin C Robin
The sleep lipid oleamide may represent an endogenous anticonvulsant: an in vitro comparative study in the 4-aminopyridine rat brain-slice model.
Neuropharmacology 2004;46(4):541-54.
2004: Ganellin C Robin
Robin Ganellin gives his views on medicinal chemistry and drug discovery. Interview by Stephen L. Carney.
Drug discovery today 2004;9(4):158-60.
2004: Narenjkar Jamshid; Assem El-Sayed K; Ganellin C Robin
Inhibition of the antigen-induced activation of RBL-2H3 cells by cetiedil and some of its analogues.
European journal of pharmacology 2004;483(2-3):107-16.
2004: Dougalis Antonios; Lees George; Ganellin C Robin
The sleep inducing brain lipid cis-oleamide (cOA) does not modulate serotonergic transmission in the CA1 pyramidal neurons of the hippocampus in vitro.
Neuropharmacology 2004;46(1):63-73.
2003: Gbahou Florence; Rouleau Agnès; Morisset Séverine; Parmentier Régis; Crochet Sylvain; Lin Jian-Sheng; Ligneau Xavier; Tardivel-Lacombe Joël; Stark Holger; Schunack Walter; Ganellin C Robin; Schwartz Jean-Charles; Arrang Jean-Michel
Protean agonism at histamine H3 receptors in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):11086-91.
2003: Grassmann Sven; Apelt Joachim; Sippl Wolfgang; Ligneau Xavier; Pertz Heinz H; Zhao Yuan Hui; Arrang Jean Michel; Ganellin C Robin; Schwartz Jean Charles; Schunack Walter; Stark Holger
Imidazole derivatives as a novel class of hybrid compounds with inhibitory histamine N-methyltransferase potencies and histamine hH3 receptor affinities.
Bioorganic & medicinal chemistry 2003;11(10):2163-74.
2003: Mikó Tibor; Ligneau Xavier; Pertz Heinz H; Ganellin C Robin; Arrang Jean-Michel; Schwartz Jean-Charles; Schunack Walter; Stark Holger
Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
Journal of medicinal chemistry 2003;46(8):1523-30.
2003: Schwartz J C; Morisset S; Rouleau A; Ligneau X; Gbahou F; Tardivel-Lacombe J; Stark H; Schunack W; Ganellin C R; Arrang J M
Therapeutic implications of constitutive activity of receptors: the example of the histamine H3 receptor.
Journal of neural transmission. Supplementum 2003;(64):1-16.
2002: Sasse Astrid; Ligneau Xavier; Rouleau Agnès; Elz Sigurd; Ganellin C Robin; Arrang Jean-Michel; Schwartz Jean-Charles; Schunack Walter; Stark Holger
Influence of bulky substituents on histamine h(3) receptor agonist/antagonist properties.
Journal of medicinal chemistry 2002;45(18):4000-10.
2002: Meier Galina; Ligneau Xavier; Pertz Heinz H; Ganellin C Robin; Schwartz Jean-Charles; Schunack Walter; Stark Holger
Piperidino-hydrocarbon compounds as novel non-imidazole histamine H(3)-receptor antagonists.
Bioorganic & medicinal chemistry 2002;10(8):2535-42.
2002: Grassmann Sven; Sadek Bassem; Ligneau Xavier; Elz Sigurd; Ganellin C Robin; Arrang Jean-Michel; Schwartz Jean-Charles; Stark Holger; Schunack Walter
Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H(3)-receptor antagonists.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;15(4):367-78.
2002: Zunszain Patricia A; Shah Mala M; Miscony Zena; Javadzadeh-Tabatabaie Mazyar; Haylett Dennis G; Ganellin C Robin
Tritylamino aromatic heterocycles and related carbinols as blockers of ca 2+-activated potassium ion channels underlying neuronal hyperpolarization.
Archiv der Pharmazie 2002;335(4):159-66.
2002: Apelt Joachim; Ligneau Xavier; Pertz Heinz H; Arrang Jean-Michel; Ganellin C Robin; Schwartz Jean-Charles; Schunack Walter; Stark Holger
Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity.
Journal of medicinal chemistry 2002;45(5):1128-41.
2001: Roxburgh C J; Ganellin C R; Athmani S; Bisi A; Quaglia W; Benton D C; Shiner M A; Malik-Hall M; Haylett D G; Jenkinson D H
Synthesis and structure-activity relationships of cetiedil analogues as blockers of the Ca(2+)-activated K+ permeability of erythrocytes.
Journal of medicinal chemistry 2001;44(20):3244-53.
2001: Meier G; Apelt J; Reichert U; Grassmann S; Ligneau X; Elz S; Leurquin F; Ganellin C R; Schwartz J C; Schunack W; Stark H
Influence of imidazole replacement in different structural classes of histamine H(3)-receptor antagonists.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;13(3):249-59.
2001: Stark H; Sippl W; Ligneau X; Arrang J M; Ganellin C R; Schwartz J C; Schunack W
Different antagonist binding properties of human and rat histamine H3 receptors.
Bioorganic & medicinal chemistry letters 2001;11(7):951-4.
2001: Sasse A; Ligneau X; Sadek B; Elz S; Pertz H H; Ganellin C R; Arrang J M; Schwartz J C; Schunack W; Stark H
Benzophenone derivatives and related compounds as potent histamine H3-receptor antagonists and potential PET/SPECT ligands.
Archiv der Pharmazie 2001;334(2):45-52.
2001: Shah M M; Miscony Z; Javadzadeh-Tabatabaie M; Ganellin C R; Haylett D G
Clotrimazole analogues: effective blockers of the slow afterhyperpolarization in cultured rat hippocampal pyramidal neurones.
British journal of pharmacology 2001;132(4):889-98.
2001: Nicholson R A; Zheng J; Ganellin C R; Verdon B; Lees G
Anesthetic-like interaction of the sleep-inducing lipid oleamide with voltage-gated sodium channels in mammalian brain.
Anesthesiology 2001;94(1):120-8.
2001: Stark H; Arrang J M; Ligneau X; Garbarg M; Ganellin C R; Schwartz J C; Schunack W
The histamine H3 receptor and its ligands.
Progress in medicinal chemistry 2001;38():279-308.
2000: Morisset S; Rouleau A; Ligneau X; Gbahou F; Tardivel-Lacombe J; Stark H; Schunack W; Ganellin C R; Schwartz J C; Arrang J M
High constitutive activity of native H3 receptors regulates histamine neurons in brain.
Nature 2000;408(6814):860-4.
2000: Ligneau X; Morisset S; Tardivel-Lacombe J; Gbahou F; Ganellin C R; Stark H; Schunack W; Schwartz J C; Arrang J M
Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.
British journal of pharmacology 2000;131(7):1247-50.
2000: Stark H; Ligneau X; Sadek B; Ganellin C R; Arrang J M; Schwartz J C; Schunack W
Analogues and derivatives of ciproxifan, a novel prototype for generating potent histamine H3-receptor antagonists.
Bioorganic & medicinal chemistry letters 2000;10(20):2379-82.
2000: Stark H; Sadek B; Krause M; Hüls A; Ligneau X; Ganellin C R; Arrang J M; Schwartz J C; Schunack W
Novel histamine H(3)-receptor antagonists with carbonyl-substituted 4-(3-(phenoxy)propyl)-1H-imidazole structures like ciproxifan and related compounds.
Journal of medicinal chemistry 2000;43(21):3987-94.
2000: Chen J Q; Galanakis D; Ganellin C R; Dunn P M; Jenkinson D H
bis-Quinolinium cyclophanes: 8,14-diaza-1,7(1, 4)-diquinolinacyclotetradecaphane (UCL 1848), a highly potent and selective, nonpeptidic blocker of the apamin-sensitive Ca(2+)-activated K(+) channel.
Journal of medicinal chemistry 2000;43(19):3478-81.
2000: Sasse A; Sadek B; Ligneau X; Elz S; Pertz H H; Luger P; Ganellin C R; Arrang J M; Schwartz J C; Schunack W; Stark H
New histamine H(3)-receptor ligands of the proxifan series: imoproxifan and other selective antagonists with high oral in vivo potency.
Journal of medicinal chemistry 2000;43(17):3335-43.
2000: Kiec-Kononowicz K; Wiecek M; Sasse A; Ligneau X; Elz S; Ganellin C R; Schwartz J C; Stark H; Schunack W
Importance of the lipophilic group in carbamates having histamine H3-receptor antagonist activity.
Die Pharmazie 2000;55(5):349-55.
2000: Sasse A; Stark H; Ligneau X; Elz S; Reidemeister S; Ganellin C R; Schwartz J C; Schunack W
(Partial) agonist/antagonist properties of novel diarylalkyl carbamates on histamine H3 receptors.
Bioorganic & medicinal chemistry 2000;8(5):1139-49.
2000: Malik-Hall M; Ganellin C R; Galanakis D; Jenkinson D H
Compounds that block both intermediate-conductance (IK(Ca)) and small-conductance (SK(Ca)) calcium-activated potassium channels.
British journal of pharmacology 2000;129(7):1431-8.
2000: Reidemeister S; Stark H; Ligneau X; Ganellin C R; Schwartz J C; Schunack W
Substituted N-phenylcarbamates as histamine H3 receptor antagonists with improved in vivo potency.
Die Pharmazie 2000;55(2):83-6.
2000: Ganellin C R; Bishop P B; Bambal R B; Chan S M; Law J K; Marabout B; Luthra P M; Moore A N; Peschard O; Bourgeat P; Rose C; Vargas F; Schwartz J C
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors.
Journal of medicinal chemistry 2000;43(4):664-74.
2000: Campos Rosa J; Galanakis D; Piergentili A; Bhandari K; Ganellin C R; Dunn P M; Jenkinson D H
Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: potent, non-peptidic blockers of the apamin-sensitive Ca(2+)-activated K(+) channel.
Journal of medicinal chemistry 2000;43(3):420-31.
1999: Sasse A; Stark H; Reidemeister S; Hüls A; Elz S; Ligneau X; Ganellin C R; Schwartz J C; Schunack W
Novel partial agonists for the histamine H(3) receptor with high in vitro and in vivo activity.
Journal of medicinal chemistry 1999;42(20):4269-74.
1999: Sasse A; Kiec-Kononowicz K; Stark H; Motyl M; Reidemeister S; Ganellin C R; Ligneau X; Schwartz J C; Schunack W
Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity.
Journal of medicinal chemistry 1999;42(4):593-600.
1999: Benton D C; Roxburgh C J; Ganellin C R; Shiner M A; Jenkinson D H
Differences in the actions of some blockers of the calcium-activated potassium permeability in mammalian red cells.
British journal of pharmacology 1999;126(1):169-78.
1998: Ganellin C R; Leurquin F; Piripitsi A; Arrang J M; Garbarg M; Ligneau X; Schunack W; Schwartz J C
Synthesis of potent non-imidazole histamine H3-receptor antagonists.
Archiv der Pharmazie 1998;331(12):395-404.
1998: Ligneau X; Lin J; Vanni-Mercier G; Jouvet M; Muir J L; Ganellin C R; Stark H; Elz S; Schunack W; Schwartz J
Neurochemical and behavioral effects of ciproxifan, a potent histamine H3-receptor antagonist.
The Journal of pharmacology and experimental therapeutics 1998;287(2):658-66.
1998: Lees G; Edwards M D; Hassoni A A; Ganellin C R; Galanakis D
Modulation of GABA(A) receptors and inhibitory synaptic currents by the endogenous CNS sleep regulator cis-9,10-octadecenoamide (cOA).
British journal of pharmacology 1998;124(5):873-82.
1998: Rosa J C; Galanakis D; Ganellin C R; Dunn P M; Jenkinson D H
Bis-quinolinium cyclophanes: 6,10-diaza-3(1,3),8(1,4)-dibenzena-1,5(1,4)- diquinolinacyclodecaphane (UCL 1684), the first nanomolar, non-peptidic blocker of the apamin-sensitive Ca(2+)-activated K+ channel.
Journal of medicinal chemistry 1998;41(1):2-5.
1997: Hill S J; Ganellin C R; Timmerman H; Schwartz J C; Shankley N P; Young J M; Schunack W; Levi R; Haas H L
International Union of Pharmacology. XIII. Classification of histamine receptors.
Pharmacological reviews 1997;49(3):253-78.
1996: Galanakis D; Ganellin C R; Dunn P M; Jenkinson D H
On the concept of a bivalent pharmacophore for SKCa channel blockers: synthesis, pharmacological testing, and radioligand binding studies on mono-, bis-, and tris-quinolinium compounds.
Archiv der Pharmazie 1996;329(12):524-8.
1996: Campos Rosa J; Galanakis D; Ganellin C R; Dunn P M
Synthesis, molecular modeling, and K+ channel-blocking activity of dequalinium analogues having semirigid linkers.
Journal of medicinal chemistry 1996;39(21):4247-54.
1996: Ganellin C R; Fkyerat A; Bang-Andersen B; Athmani S; Tertiuk W; Garbarg M; Ligneau X; Schwartz J C
A novel series of (phenoxyalkyl)imidazoles as potent H3-receptor histamine antagonists.
Journal of medicinal chemistry 1996;39(19):3806-13.
1996: Roxburgh C J; Ganellin C R; Shiner M A; Benton D C; Dunn P M; Ayalew Y; Jenkinson D H
The synthesis and some pharmacological actions of the enantiomers of the K(+)-channel blocker cetiedil.
The Journal of pharmacy and pharmacology 1996;48(8):851-7.
1996: Galanakis D; Ganellin C R; Malik S; Dunn P M
Synthesis and pharmacological testing of dequalinium analogues as blockers of the apamin-sensitive Ca(2+)-activated K+ channel: variation of the length of the alkylene chain.
Journal of medicinal chemistry 1996;39(18):3592-5.
1996: Dunn P M; Benton D C; Campos Rosa J; Ganellin C R; Jenkinson D H
Discrimination between subtypes of apamin-sensitive Ca(2+)-activated K+ channels by gallamine and a novel bis-quaternary quinolinium cyclophane, UCL 1530.
British journal of pharmacology 1996;117(1):35-42.
1996: Galanakis D; Davis C A; Ganellin C R; Dunn P M
Synthesis and quantitative structure-activity relationship of a novel series of small conductance Ca(2+)-activated K+ channel blockers related to dequalinium.
Journal of medicinal chemistry 1996;39(2):359-70.
1995: Galanakis D; Calder J A; Ganellin C R; Owen C S; Dunn P M
Synthesis and quantitative structure-activity relationships of dequalinium analogues as K+ channel blockers: investigation into the role of the substituent at position 4 of the quinoline ring.
Journal of medicinal chemistry 1995;38(18):3536-46.
1995: Ganellin C R; Hosseini S K; Khalaf Y S; Tertiuk W; Arrang J M; Garbarg M; Ligneau X; Schwartz J C
Design of potent non-thiourea H3-receptor histamine antagonists.
Journal of medicinal chemistry 1995;38(17):3342-50.
1995: Ganellin C R; Fkyerat A; Hosseini S K; Khalaf Y S; Piripitsi A; Tertiuk W; Arrang J M; Garbarg M; Ligneau X; Schwartz J C
Structure-activity studies with histamine H3-receptor ligands.
Journal de pharmacie de Belgique 1995;50(2-3):179-87.
1995: Galanakis D; Davis C A; Del Rey Herrero B; Ganellin C R; Dunn P M; Jenkinson D H
Synthesis and structure-activity relationships of dequalinium analogues as K+ channel blockers. Investigations on the role of the charged heterocycle.
Journal of medicinal chemistry 1995;38(4):595-606.
1994: Black J W; Duncan W A; Emmett J C; Ganellin C R; Hesselbo T; Parsons M E; Wyllie J H
Metiamide--an orally active histamine H2-receptor antagonist. 1973.
Agents and actions 1994;43(3-4):91-5; discussion 96.
1994: Durant G J; Ganellin C R; Parsons M E
Dimaprit, [S-[3-(N,N-dimethylamino)propyl]isothiourea]. A highly specific histamine H2-receptor agonist. Part 2. Structure-activity considerations. 1977.
Agents and actions 1994;43(3-4):139-43.
1994: Parsons M E; Owen D A; Ganellin C R; Durant G J
Dimaprit--[S-[3-(N,N-dimethylamino)propyl]isothiourea]--a highly specific histamine H2-receptor agonist. Part 1. Pharmacology. 1977.
Agents and actions 1994;43(3-4):132-8.
1994: Calder J A; Ganellin C R
Predicting the brain-penetrating capability of histaminergic compounds.
Drug design and discovery 1994;11(4):259-68.
1994: Bannister C; Burns K; Prout K; Watkin D J; Cooper D G; Duránt G J; Ganellin C R; Ife R J; Sach G S
Structures of histamine H1-receptor antagonists derived from the cimetidine group of histamine H2-receptor antagonists.
Acta crystallographica. Section B, Structural science 1994;50 ( Pt 2)():221-43.
1992: Garbarg M; Arrang J M; Rouleau A; Ligneau X; Tuong M D; Schwartz J C; Ganellin C R
S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist.
The Journal of pharmacology and experimental therapeutics 1992;263(1):304-10.
1992: Ruat M; Traiffort E; Garbarg M; Schwartz J C; Demonchaux P; Ife R J; Tertiuk W; Ganellin C R
Design of an affinity matrix for purification of the histamine H1 receptor from guinea pig cerebellum.
Journal of neurochemistry 1992;58(1):350-6.
1991: Cooper D G; Durant G J; Ganellin C R; Ife R J; Meeson M L; Sach G S
Structure-activity studies of pyridinylalkyl-isocytosine H1-receptor antihistamines and identification of an active conformation.
Farmaco (Società chimica italiana : 1989) 1991;46(1):3-19.
1990: Ruat M; Bouthenet M L; Schwartz J C; Ganellin C R
Histamine H1-receptor in heart: unique electrophoretic mobility and autoradiographic localization.
Journal of neurochemistry 1990;55(2):379-85.
1988: Chatenoud L; Villemain F; Hoebeke J; Garbarg M; Korner M; Gros C; Ruat M; Cazenave P A; Ganellin C R; Bach J F
Polyclonal and monoclonal antibodies directed against SK & F 94461, a specific H1 histamine receptor ligand.
Molecular pharmacology 1988;34(2):136-44.
1988: Shankley N P; Black J W; Ganellin C R; Mitchell R C
Correlation between log POCT/H2O and pKB estimates for a series of muscarinic and histamine H2-receptor antagonists.
British journal of pharmacology 1988;94(1):264-74.
1988: Ruat M; Körner M; Garbarg M; Gros C; Schwartz J C; Tertiuk W; Ganellin C R
Characterization of histamine H1-receptor binding peptides in guinea pig brain using [125I]iodoazidophenpyramine, an irreversible specific photoaffinity probe.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2743-7.
1988: Young R C; Mitchell R C; Brown T H; Ganellin C R; Griffiths R; Jones M; Rana K K; Saunders D; Smith I R; Sore N E
Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists.
Journal of medicinal chemistry 1988;31(3):656-71.
1988: Calcutt C R; Ganellin C R; Griffiths R; Leigh B K; Maguire J P; Mitchell R C; Mylek M E; Parsons M E; Smith I R; Young R C
Zolantidine (SK&F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist.
British journal of pharmacology 1988;93(1):69-78.
1987: Young R C; Ganellin C R; Graham M J; Mitchell R C; Roantree M L; Tashma Z
Zwitterionic analogues of cimetidine as H2 receptor antagonists.
Journal of medicinal chemistry 1987;30(7):1150-6.
1987: Calcutt C R; Ganellin C R; Jackson B; Leigh B K; Owen D A; Smith I R
Evidence for low brain penetration by the H1-receptor antagonist temelastine (SK&F 93944).
European journal of pharmacology 1987;133(1):65-74.
1986: Blakemore R C; Ganellin C R; Leigh B K; Parsons M E; Price C A; Smith I R; Tertiuk W
N-Methyldimaprit (SK&F92054). A chemical control for the histamine H2-receptor agonist dimaprit.
Agents and actions 1986;19(1-2):18-25.
1986: Ganellin C R; Blakemore R C; Brown T H; Cooper D G; Durant G J; Harvey C A; Ife R J; Owen D A; Parsons M E; Rasmussen A C
Icotidine, an antagonist of histamine at both H1 and H2 receptors.
New England and regional allergy proceedings 1986;7(2):126-33.
1986: Korner M; Bouthenet M L; Ganellin C R; Garbarg M; Gros C; Ife R J; Sales N; Schwartz J C
[125I]Iodobolpyramine, a highly sensitive probe for histamine H1-receptors in guinea-pig brain.
European journal of pharmacology 1986;120(2):151-60.
1986: Young R C; Durant G J; Emmett J C; Ganellin C R; Graham M J; Mitchell R C; Prain H D; Roantree M L
Dipole moment in relation to H2 receptor histamine antagonist activity for cimetidine analogues.
Journal of medicinal chemistry 1986;29(1):44-9.
1985: Durant G J; Ganellin C R; Hills D W; Miles P D; Parsons M E; Pepper E S; White G R
The histamine H2 receptor agonist impromidine: synthesis and structure-activity considerations.
Journal of medicinal chemistry 1985;28(10):1414-22.
1982: Emmett J C; Durant G J; Ganellin C R; Roe A M; Turner J L
Potential histamine H2-receptor antagonists. 4. Benzylhistamines.
Journal of medicinal chemistry 1982;25(10):1168-74.
1980: Smith I R; Cleverley M T; Ganellin C R; Metters K M
Binding of [3H]cimetidine to rat brain tissue.
Agents and actions 1980;10(5):422-6.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Robin Ganellin

Research Profile (preview)

Chemicals & Drugs

Living Beings

Concepts & Ideas

Anatomy

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Robin Ganellin (preview)

All Publications