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Maureen Gannon

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Maria P Alfaro; Jayasri DasGupta; Jeffrey M Davidson; Desirae L Deskins; Maureen Gannon; Lillian B Nanney; Meredith Wallus; Michelle A Guney; Pampee P Young
A physiological role for connective tissue growth factor in early wound healing.
Kathryn D Henley; Kimberly A Gooding; Aris N Economides; Maureen Gannon
Inactivation of the dual Bmp/Wnt inhibitor Sostdc1 enhances pancreatic islet function.
Uma Gunasekaran; Courtney W Hudgens; Matthew F Maulis; Brian T Wright; Maureen Gannon
Differential regulation of embryonic and adult β cell replication.

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All Publications

2013: Maria P Alfaro; Jayasri DasGupta; Jeffrey M Davidson; Desirae L Deskins; Maureen Gannon; Lillian B Nanney; Meredith Wallus; Michelle A Guney; Pampee P Young
A physiological role for connective tissue growth factor in early wound healing.
Laboratory investigation; a journal of technical methods and pathology 2013;93(1):81-95.
2012: Kathryn D Henley; Kimberly A Gooding; Aris N Economides; Maureen Gannon
Inactivation of the dual Bmp/Wnt inhibitor Sostdc1 enhances pancreatic islet function.
American journal of physiology. Endocrinology and metabolism 2012;303(6):E752-61.
2012: Uma Gunasekaran; Courtney W Hudgens; Matthew F Maulis; Brian T Wright; Maureen Gannon
Differential regulation of embryonic and adult β cell replication.
Cell cycle (Georgetown, Tex.) 2012;11(13):2431-42.
2012: Rachel B Reinert; Marcela Brissova; Maureen Gannon; Jeannelle Kantz; Amanda Ackermann Misfeldt; Greg Poffenberger; Alvin C Powers
Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice.
PloS one 2012;7(3):e33529.
2011: Michelle A Guney; Anna L Means; Renuka Menon; Christine P Petersen; Courtney Warfield; Andre Boustani; Matthew R Duncan; Aris N Economides; Gary Grotendorst; Uma Gunasekaran; Maureen Gannon
Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(37):15242-7.
2011: Uma Gunasekaran; Maureen Gannon
Type 2 diabetes and the aging pancreatic beta cell.
Aging 2011;3(6):565-75.
2010: Barton Wicksteed; Marcela Brissova; Wenbo Yan; Darren M Opland; Jennifer L Plank; Rachel B Reinert; Lorna M Dickson; Natalia A Tamarina; Louis H Philipson; Alena Shostak; Ernesto Bernal-Mizrachi; Lynda Elghazi-Cras; Michael W Roe; Patricia A Labosky; Martin G Myers Jr; Maureen Gannon; Alvin C Powers; Peter J Dempsey
Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.
Diabetes 2010;59(12):3090-8.
2010: Hongjie Zhang; Jia Zhang; Christine F Pope; Laura A Crawford; Rupangi C Vasavada; Shubhada M Jagasia; Maureen Gannon
Gestational diabetes mellitus resulting from impaired beta-cell compensation in the absence of FoxM1, a novel downstream effector of placental lactogen.
Diabetes 2010;59(1):143-52.
2010: John Virostko; Aramandla Radhika; Greg Poffenberger; Zhongyi Chen; Marcela Brissova; Joshua Gilchrist; Brian Coleman; Maureen Gannon; E Duco Jansen; Alvin C Powers
Bioluminescence imaging in mouse models quantifies beta cell mass in the pancreas and after islet transplantation.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2010;12(1):42-53.
2009: Hongjie Zhang; Elizabeth Tweedie Ables; Christine F Pope; M Kay Washington; Susan Hipkens; Anna L Means; Gunter Path; Jochen Seufert; Robert H Costa; Andrew B Leiter; Mark Magnuson; Maureen Gannon
Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation.
Mechanisms of development 2009;126(11-12):958-73.
2009: Michelle A Guney; Maureen Gannon
Pancreas cell fate.
Birth defects research. Part C, Embryo today : reviews 2009;87(3):232-48.
2009: Laura A Crawford; Michelle A Guney; Young Ah Oh; R Andrea Deyoung; David M Valenzuela; Andrew J Murphy; George D Yancopoulos; Karen M Lyons; David R Brigstock; Aris Economides; Maureen Gannon
Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis.
Molecular endocrinology (Baltimore, Md.) 2009;23(3):324-36.
2008: Amanda Ackermann Misfeldt; Robert H Costa; Maureen Gannon
Beta-cell proliferation, but not neogenesis, following 60% partial pancreatectomy is impaired in the absence of FoxM1.
Diabetes 2008;57(11):3069-77.
2008: Maureen Gannon; Elizabeth Tweedie Ables; Laura Crawford; David Lowe; Martin F Offield; Mark Magnuson; Christopher V E Wright
pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.
Developmental biology 2008;314(2):406-17.
2008: Laura Wilding Crawford; Elizabeth Tweedie Ables; Young Ah Oh; Braden Boone; Shawn Levy; Maureen Gannon
Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis.
PloS one 2008;3(2):e1611.
2007: Peter O Wiebe; Jay D Kormish; Venus T Roper; Yoshio Fujitani; Ninche I Alston; Kenneth S Zaret; Christopher V E Wright; Roland W Stein; Maureen Gannon
Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression.
Molecular and cellular biology 2007;27(11):4093-104.
2007: Yukiko Kanetsuna; Keiko Takahashi; Michio Nagata; Maureen Gannon; Matthew D Breyer; Raymond C Harris; Takamune Takahashi
Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice.
The American journal of pathology 2007;170(5):1473-84.
2007: Maureen Gannon
BuMP-ing up insulin secretion by pancreatic beta cells.
Cell metabolism 2007;5(3):157-9.
2007: Amanda M Ackermann; Maureen Gannon
Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion.
Journal of molecular endocrinology 2007;38(1-2):193-206.
2006: Elizabeth Tweedie; Isabella Artner; Laura Crawford; Greg Poffenberger; Bernard Thorens; Roland Stein; Alvin C Powers; Maureen Gannon
Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of beta-cells.
Diabetes 2006;55(12):3264-70.
2006: Yukiko Kanetsuna; Keita Hirano; Michio Nagata; Maureen Gannon; Keiko Takahashi; Raymond C Harris; Matthew D Breyer; Takamune Takahashi
Characterization of diabetic nephropathy in a transgenic model of hypoinsulinemic diabetes.
American journal of physiology. Renal physiology 2006;291(6):F1315-22.
2006: Marcela Brissova; Alena Shostak; Masakazu Shiota; Peter O Wiebe; Greg Poffenberger; Jeannelle Kantz; Zhongyi Chen; Chad Carr; W Gray Jerome; Jin Chen; H Scott Baldwin; Wendell Nicholson; David M Bader; Thomas L Jetton; Maureen Gannon; Alvin C Powers
Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function.
Diabetes 2006;55(11):2974-85.
2006: Daniel F Boyer; Yoshio Fujitani; Maureen Gannon; Alvin C Powers; Roland W Stein; Christopher V E Wright
Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression.
Developmental biology 2006;298(2):616-31.
2006: Hongjie Zhang; Amanda M Ackermann; Galina A Gusarova; David Lowe; Xue Feng; Usa G Kopsombut; Robert H Costa; Maureen Gannon
The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass.
Molecular endocrinology (Baltimore, Md.) 2006;20(8):1853-66.
2006: Yoshio Fujitani; Shuko Fujitani; Daniel F Boyer; Maureen Gannon; Yoshiya Kawaguchi; Michael Ray; Masakazu Shiota; Roland W Stein; Mark Magnuson; Christopher V E Wright
Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.
Genes & development 2006;20(2):253-66.
2005: Hongjie Zhang; Yoshio Fujitani; Christopher V E Wright; Maureen Gannon
Efficient recombination in pancreatic islets by a tamoxifen-inducible Cre-recombinase.
Genesis (New York, N.Y. : 2000) 2005;42(3):210-7.
2004: Claudia Frigeri; Cyrus C Martin; Christina A Svitek; James K Oeser; John C Hutton; Maureen Gannon; Richard M O'Brien
The proximal islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen promoter is sufficient to initiate but not maintain transgene expression in mouse islets in vivo.
Diabetes 2004;53(7):1754-64.
2004: Marcela Brissova; Michael Fowler; Peter O Wiebe; Alena Shostak; Masakazu Shiota; Aramandla Radhika; P Charles Lin; Maureen Gannon; Alvin C Powers
Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets.
Diabetes 2004;53(5):1318-25.
2004: Laura Wilding; Maureen Gannon
The role of pdx1 and HNF6 in proliferation and differentiation of endocrine precursors.
Diabetes/metabolism research and reviews 2004;20(2):114-23.
2002: Yoshiya Kawaguchi; Bonnie Cooper; Maureen Gannon; Michael Ray; Raymond J MacDonald; Christopher V E Wright
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors.
Nature genetics 2002;32(1):128-34.
2002: Susan E Samaras; Michelle A Cissell; Kevin Gerrish; Christopher V E Wright; Maureen Gannon; Roland Stein
Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6.
Molecular and cellular biology 2002;22(13):4702-13.
2002: Marcela Brissova; Masakazu Shiota; Wendell E Nicholson; Maureen Gannon; Susan M Knobel; David W Piston; Christopher V E Wright; Alvin C Powers
Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion.
The Journal of biological chemistry 2002;277(13):11225-32.
2001: Maureen Gannon; Laura Gamer; Christopher V E Wright
Regulatory regions driving developmental and tissue-specific expression of the essential pancreatic gene pdx1.
Developmental biology 2001;238(1):185-201.
2000: Maureen Gannon; MK Ray; K Van Zee; Francisco M Rausa; Robert H Costa; Christopher V E Wright
Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function.
Development (Cambridge, England) 2000;127(13):2883-95.
2000: Kevin Gerrish; Maureen Gannon; D Shih; Eva Henderson; M Stoffel; Christopher V E Wright; Roland Stein
Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites.
The Journal of biological chemistry 2000;275(5):3485-92.
2000: Maureen Gannon; P L Herrera; Christopher V E Wright
Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter.
Genesis (New York, N.Y. : 2000) 2000;26(2):143-4.
2000: Maureen Gannon; Chiyo Shiota; C Postic; Christopher V E Wright; Mark Magnuson
Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas.
Genesis (New York, N.Y. : 2000) 2000;26(2):139-42.
1997: K L Wu; Maureen Gannon; M Peshavaria; M F Offield; Eva Henderson; M Ray; A Marks; Laura Gamer; Christopher V E Wright; Roland Stein
Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene.
Molecular and cellular biology 1997;17(10):6002-13.