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Hong Qiang Gao

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TOP 3
A Geoffrey Skillman; Karl W Maurer; Diana C Roe; Margaret J Stauber; Dolan Eargle; Todd J A Ewing; Angelika Muscate; Elisabeth Davioud; Maxine V Medaglia; Robert J Fisher; Eddy Arnold; Hong Qiang Gao; Robert W Buckheit; Paul L Boyer; Stephen H Hughes; Irwin D Kuntz; George L Kenyon
A novel mechanism for inhibition of HIV-1 reverse transcriptase.
Hong Qiang Gao; Stefan G Sarafianos; Eddy Arnold; Stephen H Hughes
RNase H cleavage of the 5' end of the human immunodeficiency virus type 1 genome.
Paul L Boyer; Hong Qiang Gao; Patrick K Clark; Stefan G Sarafianos; Eddy Arnold; Stephen H Hughes
YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitro.

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2002: A Geoffrey Skillman; Karl W Maurer; Diana C Roe; Margaret J Stauber; Dolan Eargle; Todd J A Ewing; Angelika Muscate; Elisabeth Davioud; Maxine V Medaglia; Robert J Fisher; Eddy Arnold; Hong Qiang Gao; Robert W Buckheit; Paul L Boyer; Stephen H Hughes; Irwin D Kuntz; George L Kenyon
A novel mechanism for inhibition of HIV-1 reverse transcriptase.
Bioorganic chemistry 2002;30(6):443-58.
2001: Hong Qiang Gao; Stefan G Sarafianos; Eddy Arnold; Stephen H Hughes
RNase H cleavage of the 5' end of the human immunodeficiency virus type 1 genome.
Journal of virology 2001;75(23):11874-80.
2001: Paul L Boyer; Hong Qiang Gao; Patrick K Clark; Stefan G Sarafianos; Eddy Arnold; Stephen H Hughes
YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitro.
Journal of virology 2001;75(14):6321-8.
2001: Paul L Boyer; Hong Qiang Gao; P Frank; Patrick K Clark; Stephen H Hughes
The basic loop of the RNase H domain of MLV RT is important both for RNase H and for polymerase activity.
Virology 2001;282(1):206-13.
2000: Hong Qiang Gao; Paul L Boyer; Stefan G Sarafianos; Eddy Arnold; Stephen H Hughes
The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
Journal of molecular biology 2000;300(2):403-18.
1999: Hong Qiang Gao; Stefan G Sarafianos; Eddy Arnold; Stephen H Hughes
Similarities and differences in the RNase H activities of human immunodeficiency virus type 1 reverse transcriptase and Moloney murine leukemia virus reverse transcriptase.
Journal of molecular biology 1999;294(5):1097-113.
1998: Hong Qiang Gao; Paul L Boyer; Eddy Arnold; Stephen H Hughes
Effects of mutations in the polymerase domain on the polymerase, RNase H and strand transfer activities of human immunodeficiency virus type 1 reverse transcriptase.
Journal of molecular biology 1998;277(3):559-72.
1998: Paul L Boyer; Hong Qiang Gao; Stephen H Hughes
A mutation at position 190 of human immunodeficiency virus type 1 reverse transcriptase interacts with mutations at positions 74 and 75 via the template primer.
Antimicrobial agents and chemotherapy 1998;42(2):447-52.
1997: Shoshana Loya; Hong Qiang Gao; Orna Avidan; Paul L Boyer; Stephen H Hughes; Amnon Hizi
Subunit-specific mutagenesis of the cysteine 280 residue of the reverse transcriptase of human immunodeficiency virus type 1: effects on sensitivity to a specific inhibitor of the RNase H activity.
Journal of virology 1997;71(7):5668-72.