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Subbu Apparsundaram

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Xingrong Liu; Olga Vilenski; Joyce Kwan; Subbu Apparsundaram; Robert Weikert
Unbound brain concentration determines receptor occupancy: a correlation of drug concentration and brain serotonin and dopamine reuptake transporter occupancy for eighteen compounds in rats.
Jun Zhu; Subbu Apparsundaram; Linda P Dwoskin
Nicotinic receptor activation increases [3H]dopamine uptake and cell surface expression of dopamine transporters in rat prefrontal cortex.
Renee S Martin; Robert A Henningsen; Alexander Suen; Subbu Apparsundaram; Becky Leung; Zhongjiang Jia; Rama K Kondru; Marcos E Milla
Kinetic and thermodynamic assessment of binding of serotonin transporter inhibitors.

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All Publications

2009: Xingrong Liu; Olga Vilenski; Joyce Kwan; Subbu Apparsundaram; Robert Weikert
Unbound brain concentration determines receptor occupancy: a correlation of drug concentration and brain serotonin and dopamine reuptake transporter occupancy for eighteen compounds in rats.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(7):1548-56.
2009: Jun Zhu; Subbu Apparsundaram; Linda P Dwoskin
Nicotinic receptor activation increases [3H]dopamine uptake and cell surface expression of dopamine transporters in rat prefrontal cortex.
The Journal of pharmacology and experimental therapeutics 2009;328(3):931-9.
2008: Renee S Martin; Robert A Henningsen; Alexander Suen; Subbu Apparsundaram; Becky Leung; Zhongjiang Jia; Rama K Kondru; Marcos E Milla
Kinetic and thermodynamic assessment of binding of serotonin transporter inhibitors.
The Journal of pharmacology and experimental therapeutics 2008;327(3):991-1000.
2008: Subbu Apparsundaram; Daniel J Stockdale; Robert A Henningsen; Marcos E Milla; Renee S Martin
Antidepressants targeting the serotonin reuptake transporter act via a competitive mechanism.
The Journal of pharmacology and experimental therapeutics 2008;327(3):982-90.
2007: Justin Nickell; Michael F Salvatore; Francois Pomerleau; Subbu Apparsundaram; Greg A Gerhardt
Reduced plasma membrane surface expression of GLAST mediates decreased glutamate regulation in the aged striatum.
Neurobiology of aging 2007;28(11):1737-48.
2007: Lisa S Middleton; Subbu Apparsundaram; Kelley A King-Pospisil; Linda P Dwoskin
Nicotine increases dopamine transporter function in rat striatum through a trafficking-independent mechanism.
European journal of pharmacology 2007;554(2-3):128-36.
2006: Vinay Parikh; Subbu Apparsundaram; Rouba Kozak; J B Richards; Martin Sarter
Reduced expression and capacity of the striatal high-affinity choline transporter in hyperdopaminergic mice.
Neuroscience 2006;141(1):379-89.
2005: Jun Zhu; Subbu Apparsundaram; Michael T Bardo; Linda P Dwoskin
Environmental enrichment decreases cell surface expression of the dopamine transporter in rat medial prefrontal cortex.
Journal of neurochemistry 2005;93(6):1434-43.
2005: Subbu Apparsundaram; Vicente Martinez; Vinay Parikh; Rouba Kozak; Martin Sarter
Increased capacity and density of choline transporters situated in synaptic membranes of the right medial prefrontal cortex of attentional task-performing rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(15):3851-6.
2004: Lixin Zhang; Anita Fletcher-Turner; Mark A Marchionni; Subbu Apparsundaram; Kerstin H Lundgren; David M Yurek; Kim B Seroogy
Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures.
Journal of neurochemistry 2004;91(6):1358-68.
2004: Jeremiah Gates; Shawn M Ferguson; Randy D Blakely; Subbu Apparsundaram
Regulation of choline transporter surface expression and phosphorylation by protein kinase C and protein phosphatase 1/2A.
The Journal of pharmacology and experimental therapeutics 2004;310(2):536-45.
2004: Wendell S Akers; Shilpa K Shah; Jeremy D Flynn; Subbu Apparsundaram
Effect of clonidine on cardiac norepinephrine spillover in isolated rat heart.
Journal of cardiovascular pharmacology 2004;43(6):830-8.
2003: Michael F Salvatore; Subbu Apparsundaram; Greg A Gerhardt
Decreased plasma membrane expression of striatal dopamine transporter in aging.
Neurobiology of aging 2003;24(8):1147-54.
2003: Shawn M Ferguson; Valentina Savchenko; Subbu Apparsundaram; Melissa Zwick; Jane Wright; Craig J Heilman; Hong Yi; Allan Levey; Randy D Blakely
Vesicular localization and activity-dependent trafficking of presynaptic choline transporters.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(30):9697-709.
2003: Uhna Sung; Subbu Apparsundaram; Aurelio Galli; Kristopher M Kahlig; Valentina Savchenko; Sally Schroeter; Michael W Quick; Randy D Blakely
A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(5):1697-709.
2002: John G Partridge; Subbu Apparsundaram; Greg A Gerhardt; Jennifer Ronesi; David M Lovinger
Nicotinic acetylcholine receptors interact with dopamine in induction of striatal long-term depression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(7):2541-9.
2001: Subbu Apparsundaram; Shawn M Ferguson; Randy D Blakely
Molecular cloning and characterization of a murine hemicholinium-3-sensitive choline transporter.
Biochemical Society transactions 2001;29(Pt 6):711-6.
2001: Subbu Apparsundaram; Uhna Sung; Raymond Price; Randy D Blakely
Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells.
The Journal of pharmacology and experimental therapeutics 2001;299(2):666-77.
2001: Subbu Apparsundaram
Function and regulation of monoamine transporters: focus on the norepinephrine transporter.
CNS spectrums 2001;6(8):671-4, 677-8.
2000: Andrea L Bauman; Subbu Apparsundaram; Sammanda Ramamoorthy; Brian E Wadzinski; Roxanne A Vaughan; Randy D Blakely
Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(20):7571-8.
2000: Subbu Apparsundaram; Shawn M Ferguson; Alfred L George; Randy D Blakely
Molecular cloning of a human, hemicholinium-3-sensitive choline transporter.
Biochemical and biophysical research communications 2000;276(3):862-7.
2000: Sally Schroeter; Subbu Apparsundaram; R G Wiley; Leeann H Miner; Susan R Sesack; Randy D Blakely
Immunolocalization of the cocaine- and antidepressant-sensitive l-norepinephrine transporter.
The Journal of comparative neurology 2000;420(2):211-32.
1998: Subbu Apparsundaram; Sally Schroeter; E Giovanetti; Randy D Blakely
Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins.
The Journal of pharmacology and experimental therapeutics 1998;287(2):744-51.
1998: Subbu Apparsundaram; Aurelio Galli; Louis J DeFelice; H Criss Hartzell; Randy D Blakely
Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells.
The Journal of pharmacology and experimental therapeutics 1998;287(2):733-43.
1998: Lankupalle D Jayanthi; Subbu Apparsundaram; M D Malone; E Ward; D M Miller; M Eppler; Randy D Blakely
The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter.
Molecular pharmacology 1998;54(4):601-9.
1998: Randy D Blakely; Sammanda Ramamoorthy; Sally Schroeter; Y Qian; Subbu Apparsundaram; Aurelio Galli; Louis J DeFelice
Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins.
Biological psychiatry 1998;44(3):169-78.
1998: Randy D Blakely; Subbu Apparsundaram
Structural diversity in the catecholamine transporter gene family: molecular cloning and characterization of an L-epinephrine transporter from bullfrog sympathetic ganglia.
Advances in pharmacology (San Diego, Calif.) 1998;42():206-10.
1997: Subbu Apparsundaram; K R Moore; M D Malone; H Criss Hartzell; Randy D Blakely
Molecular cloning and characterization of an L-epinephrine transporter from sympathetic ganglia of the bullfrog, Rana catesbiana.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(8):2691-702.