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Adolfo García-Sastre

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Kochs Georg; Martínez-Sobrido Luis; Lienenklaus Stefan; Weiss Siegfried; García-Sastre Adolfo; Staeheli Peter
Strong interferon-inducing capacity of a highly virulent variant of influenza A virus strain PR8 with deletions in the NS1 gene.
Nistal-Villán Estanislao; García-Sastre Adolfo
New prospects for the rational design of antivirals.
Martínez-Sobrido Luis; Emonet Sébastien; Giannakas Panagiotis; Cubitt Beatrice; García-Sastre Adolfo; de la Torre Juan C
Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus.

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All Publications

2009: Kochs Georg; Martínez-Sobrido Luis; Lienenklaus Stefan; Weiss Siegfried; García-Sastre Adolfo; Staeheli Peter
Strong interferon-inducing capacity of a highly virulent variant of influenza A virus strain PR8 with deletions in the NS1 gene.
The Journal of general virology 2009;90(Pt 12):2990-4.
2009: Nistal-Villán Estanislao; García-Sastre Adolfo
New prospects for the rational design of antivirals.
Nature medicine 2009;15(11):1253-4.
2009: Martínez-Sobrido Luis; Emonet Sébastien; Giannakas Panagiotis; Cubitt Beatrice; García-Sastre Adolfo; de la Torre Juan C
Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus.
Journal of virology 2009;83(21):11330-40.
2009: Kuri Thomas; Zhang Xiaonan; Habjan Matthias; Martínez-Sobrido Luis; García-Sastre Adolfo; Yuan Zhenghong; Weber Friedemann
Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation.
The Journal of general virology 2009;90(Pt 11):2686-94.
2009: Gannagé Monique; Dormann Dorothee; Albrecht Randy; Dengjel Jörn; Torossi Tania; Rämer Patrick C; Lee Monica; Strowig Till; Arrey Frida; Conenello Gina; Pypaert Marc; Andersen Jens; García-Sastre Adolfo; Münz Christian
Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes.
Cell host & microbe 2009;6(4):367-80.
2009: Billharz Rosalind; Zeng Hui; Proll Sean C; Korth Marcus J; Lederer Sharon; Albrecht Randy; Goodman Alan G; Rosenzweig Elizabeth; Tumpey Terrence M; García-Sastre Adolfo; Katze Michael G
The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways.
Journal of virology 2009;83(20):10557-70.
2009: Haye Kester; Burmakina Svetlana; Moran Thomas; García-Sastre Adolfo; Fernandez-Sesma Ana
The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells.
Journal of virology 2009;83(13):6849-62.
2009: Nguyen David N; Kim Phillip; Martínez-Sobrido Luis; Beitzel Brett; García-Sastre Adolfo; Langer Robert; Anderson Daniel G
A novel high-throughput cell-based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery.
Biotechnology and bioengineering 2009;103(4):664-75.
2009: Dauber Bianca; Martínez-Sobrido Luis; Schneider Jana; Hai Rong; Waibler Zoe; Kalinke Ulrich; García-Sastre Adolfo; Wolff Thorsten
Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR.
PLoS pathogens 2009;5(6):e1000473.
2009: Ashour Joseph; Laurent-Rolle Maudry; Shi Pei-Yong; García-Sastre Adolfo
NS5 of dengue virus mediates STAT2 binding and degradation.
Journal of virology 2009;83(11):5408-18.
2009: Zamarin D; Vigil A; Kelly K; García-Sastre A; Fong Y
Genetically engineered Newcastle disease virus for malignant melanoma therapy.
Gene therapy 2009;16(6):796-804.
2009: Gack Michaela Ulrike; Albrecht Randy Allen; Urano Tomohiko; Inn Kyung-Soo; Huang I-Chueh; Carnero Elena; Farzan Michael; Inoue Satoshi; Jung Jae Ung; García-Sastre Adolfo
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I.
Cell host & microbe 2009;5(5):439-49.
2009: Weingartl Hana M; Albrecht Randy A; Lager Kelly M; Babiuk Shawn; Marszal Peter; Neufeld James; Embury-Hyatt Carissa; Lekcharoensuk Porntippa; Tumpey Terrence M; García-Sastre Adolfo; Richt Jürgen A
Experimental infection of pigs with the human 1918 pandemic influenza virus.
Journal of virology 2009;83(9):4287-96.
2009: Zamarin Dmitriy; Martínez-Sobrido Luis; Kelly Kaitlyn; Mansour Mena; Sheng Gang; Vigil Adam; García-Sastre Adolfo; Palese Peter; Fong Yuman
Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(4):697-706.
2009: Lowen Anice C; Steel John; Mubareka Samira; Carnero Elena; García-Sastre Adolfo; Palese Peter
Blocking interhost transmission of influenza virus by vaccination in the guinea pig model.
Journal of virology 2009;83(7):2803-18.
2009: Mubareka Samira; Lowen Anice C; Steel John; Coates Allan L; García-Sastre Adolfo; Palese Peter
Transmission of influenza virus via aerosols and fomites in the guinea pig model.
The Journal of infectious diseases 2009;199(6):858-65.
2009: Baskin Carole R; Bielefeldt-Ohmann Helle; Tumpey Terrence M; Sabourin Patrick J; Long James P; García-Sastre Adolfo; Tolnay Airn-E; Albrecht Randy; Pyles John A; Olson Pam H; Aicher Lauri D; Rosenzweig Elizabeth R; Murali-Krishna Kaja; Clark Edward A; Kotur Mark S; Fornek Jamie L; Proll Sean; Palermo Robert E; Sabourin Carol L; Katze Michael G
Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3455-60.
2009: Van Hoeven Neal; Pappas Claudia; Belser Jessica A; Maines Taronna R; Zeng Hui; García-Sastre Adolfo; Sasisekharan Ram; Katz Jacqueline M; Tumpey Terrence M
Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3366-71.
2009: Steel John; Lowen Anice C; Pena Lindomar; Angel Matthew; Solórzano Alicia; Albrecht Randy; Perez Daniel R; García-Sastre Adolfo; Palese Peter
Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza.
Journal of virology 2009;83(4):1742-53.
2009: Taylor Shannon L; Frias-Staheli Natalia; García-Sastre Adolfo; Schmaljohn Connie S
Hantaan virus nucleocapsid protein binds to importin alpha proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappa B.
Journal of virology 2009;83(3):1271-9.
2009: Lai Caroline; Struckhoff Jessica J; Schneider Jana; Martinez-Sobrido Luis; Wolff Thorsten; García-Sastre Adolfo; Zhang Dong-Er; Lenschow Deborah J
Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection.
Journal of virology 2009;83(2):1147-51.
2009: Carnero Elena; Li Wenjing; Borderia Antonio V; Moltedo Bruno; Moran Thomas; García-Sastre Adolfo
Optimization of human immunodeficiency virus gag expression by newcastle disease virus vectors for the induction of potent immune responses.
Journal of virology 2009;83(2):584-97.
2009: Richt Jüergen A; García-Sastre Adolfo
Attenuated influenza virus vaccines with modified NS1 proteins.
Current topics in microbiology and immunology 2009;333():177-95.
2008: Hai Rong; Martínez-Sobrido Luis; Fraser Kathryn A; Ayllon Juan; García-Sastre Adolfo; Palese Peter
Influenza B virus NS1-truncated mutants: live-attenuated vaccine approach.
Journal of virology 2008;82(21):10580-90.
2008: Vigil Adam; Martinez Osvaldo; Chua Mark A; García-Sastre Adolfo
Recombinant Newcastle disease virus as a vaccine vector for cancer therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(11):1883-90.
2008: Yu Chun I; Gallegos Michael; Marches Florentina; Zurawski Gerard; Ramilo Octavio; García-Sastre Adolfo; Banchereau Jacques; Palucka A Karolina
Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines.
Blood 2008;112(9):3671-8.
2008: Muñoz-Fontela César; Macip Salvador; Martínez-Sobrido Luis; Brown Lauren; Ashour Joseph; García-Sastre Adolfo; Lee Sam W; Aaronson Stuart A
Transcriptional role of p53 in interferon-mediated antiviral immunity.
The Journal of experimental medicine 2008;205(8):1929-38.
2008: Wang Shixia; Parker Chris; Taaffe Jessica; Solórzano Alicia; García-Sastre Adolfo; Lu Shan
Heterologous HA DNA vaccine prime--inactivated influenza vaccine boost is more effective than using DNA or inactivated vaccine alone in eliciting antibody responses against H1 or H3 serotype influenza viruses.
Vaccine 2008;26(29-30):3626-33.
2008: Wu Lan; Huang Tian-gui; Meseck Marcia; Altomonte Jennifer; Ebert Oliver; Shinozaki Katsunori; García-Sastre Adolfo; Fallon John; Mandeli John; Woo Savio L C
rVSV(M Delta 51)-M3 is an effective and safe oncolytic virus for cancer therapy.
Human gene therapy 2008;19(6):635-47.
2008: Dittmann Jan; Stertz Silke; Grimm Daniel; Steel John; García-Sastre Adolfo; Haller Otto; Kochs Georg
Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase.
Journal of virology 2008;82(7):3624-31.
2008: Pappas Claudia; Aguilar Patricia V; Basler Christopher F; Solórzano Alicia; Zeng Hui; Perrone Lucy A; Palese Peter; García-Sastre Adolfo; Katz Jacqueline M; Tumpey Terrence M
Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(8):3064-9.
2008: Shen Ching-Hung; Ge Qing; Talay Oezcan; Eisen Herman N; García-Sastre Adolfo; Chen Jianzhu
Loss of IL-7R and IL-15R expression is associated with disappearance of memory T cells in respiratory tract following influenza infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):171-8.
2008: Cockburn Ian A; Chakravarty Sumana; Overstreet Michael G; García-Sastre Adolfo; Zavala Fidel
Memory CD8+ T cell responses expand when antigen presentation overcomes T cell self-regulation.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):64-71.
2008: Steel John; Burmakina Svetlana V; Thomas Colleen; Spackman Erica; García-Sastre Adolfo; Swayne David E; Palese Peter
A combination in-ovo vaccine for avian influenza virus and Newcastle disease virus.
Vaccine 2008;26(4):522-31.
2008: Altomonte Jennifer; Wu Lan; Chen Li; Meseck Marcia; Ebert Oliver; García-Sastre Adolfo; Fallon John; Woo Savio L C
Exponential enhancement of oncolytic vesicular stomatitis virus potency by vector-mediated suppression of inflammatory responses in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(1):146-53.
2008: Loo Yueh-Ming; Fornek Jamie; Crochet Nanette; Bajwa Gagan; Perwitasari Olivia; Martinez-Sobrido Luis; Akira Shizuo; Gill Michelle A; García-Sastre Adolfo; Katze Michael G; Gale Michael
Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity.
Journal of virology 2008;82(1):335-45.
2008: Perrone Lucy A; Plowden Julie K; García-Sastre Adolfo; Katz Jacqueline M; Tumpey Terrence M
H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice.
PLoS pathogens 2008;4(8):e1000115.
2007: Frias-Staheli Natalia; Giannakopoulos Nadia V; Kikkert Marjolein; Taylor Shannon L; Bridgen Anne; Paragas Jason; Richt Juergen A; Rowland Raymond R; Schmaljohn Connie S; Lenschow Deborah J; Snijder Eric J; García-Sastre Adolfo; Virgin Herbert Whiting
Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses.
Cell host & microbe 2007;2(6):404-16.
2007: Vincent Amy L; Ma Wenjun; Lager Kelly M; Janke Bruce H; Webby Richard J; García-Sastre Adolfo; Richt Jürgen A
Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine.
Vaccine 2007;25(47):7999-8009.
2007: Martínez-Sobrido Luis; Giannakas Panagiotis; Cubitt Beatrice; García-Sastre Adolfo; de la Torre Juan Carlos
Differential inhibition of type I interferon induction by arenavirus nucleoproteins.
Journal of virology 2007;81(22):12696-703.
2007: Baskin C R; Bielefeldt-Ohmann H; García-Sastre A; Tumpey T M; Van Hoeven N; Carter V S; Thomas M J; Proll S; Solórzano A; Billharz R; Fornek J L; Thomas S; Chen C-H; Clark E A; Murali-Krishna Kaja; Katze M G
Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus.
Journal of virology 2007;81(21):11817-27.
2007: Tumpey Terrence M; Szretter Kristy J; Van Hoeven Neal; Katz Jacqueline M; Kochs Georg; Haller Otto; García-Sastre Adolfo; Staeheli Peter
The Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses.
Journal of virology 2007;81(19):10818-21.
2007: Tsuda Naotake; Chang David Z; Mine Takashi; Efferson Clay; García-Sastre Adolfo; Wang Xinhui; Ferrone Soldano; Ioannides Constantin G
Taxol increases the amount and T cell activating ability of self-immune stimulatory multimolecular complexes found in ovarian cancer cells.
Cancer research 2007;67(17):8378-87.
2007: Vigil Adam; Park Man-Seong; Martinez Osvaldo; Chua Mark A; Xiao Sa; Cros Jerome F; Martínez-Sobrido Luis; Woo Savio L C; García-Sastre Adolfo
Use of reverse genetics to enhance the oncolytic properties of Newcastle disease virus.
Cancer research 2007;67(17):8285-92.
2007: Irie Takashi; Carnero Elena; Okumura Atsushi; García-Sastre Adolfo; Harty Ronald N
Modifications of the PSAP region of the matrix protein lead to attenuation of vesicular stomatitis virus in vitro and in vivo.
The Journal of general virology 2007;88(Pt 9):2559-67.
2007: Quan Phenix-Lan; Palacios Gustavo; Jabado Omar J; Conlan Sean; Hirschberg David L; Pozo Francisco; Jack Philippa J M; Cisterna Daniel; Renwick Neil; Hui Jeffrey; Drysdale Andrew; Amos-Ritchie Rachel; Baumeister Elsa; Savy Vilma; Lager Kelly M; Richt Jürgen A; Boyle David B; García-Sastre Adolfo; Casas Inmaculada; Perez-Breña Pilar; Briese Thomas; Lipkin W Ian
Detection of respiratory viruses and subtype identification of influenza A viruses by GreeneChipResp oligonucleotide microarray.
Journal of clinical microbiology 2007;45(8):2359-64.
2007: Ghanem Alexander; Mayer Daniel; Chase Geoffrey; Tegge Werner; Frank Ronald; Kochs Georg; García-Sastre Adolfo; Schwemmle Martin
Peptide-mediated interference with influenza A virus polymerase.
Journal of virology 2007;81(14):7801-4.
2007: Roth-Cross Jessica K; Martínez-Sobrido Luis; Scott Erin P; García-Sastre Adolfo; Weiss Susan R
Inhibition of the alpha/beta interferon response by mouse hepatitis virus at multiple levels.
Journal of virology 2007;81(13):7189-99.
2007: Kochs Georg; García-Sastre Adolfo; Martínez-Sobrido Luis
Multiple anti-interferon actions of the influenza A virus NS1 protein.
Journal of virology 2007;81(13):7011-21.
2007: Escalante Carlos R; Nistal-Villán Estanislao; Shen Leyi; García-Sastre Adolfo; Aggarwal Aneel K
Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer.
Molecular cell 2007;26(5):703-16.
2007: Wang Xingyu; Hussain Sofia; Wang Emilie-Jeanne; Wang Xiuyan; Li Ming O; García-Sastre Adolfo; Beg Amer A
Lack of essential role of NF-kappa B p50, RelA, and cRel subunits in virus-induced type 1 IFN expression.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):6770-6.
2007: Stertz Silke; Reichelt Mike; Spiegel Martin; Kuri Thomas; Martínez-Sobrido Luis; García-Sastre Adolfo; Weber Friedemann; Kochs Georg
The intracellular sites of early replication and budding of SARS-coronavirus.
Virology 2007;361(2):304-15.
2007: Grimm Daniel; Staeheli Peter; Hufbauer Martin; Koerner Iris; Martínez-Sobrido Luis; Solórzano Alicia; García-Sastre Adolfo; Haller Otto; Kochs Georg
Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(16):6806-11.
2007: Puig-Basagoiti Francesc; Tilgner Mark; Bennett Corey J; Zhou Yangsheng; Muñoz-Jordán Jorge L; García-Sastre Adolfo; Bernard Kristen A; Shi Pei-Yong
A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis.
Virology 2007;361(1):229-41.
2007: Tenoever Benjamin R; Ng Sze-Ling; Chua Mark A; McWhirter Sarah M; García-Sastre Adolfo; Maniatis Tom
Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity.
Science (New York, N.Y.) 2007;315(5816):1274-8.
2007: Tumpey Terrence M; Maines Taronna R; Van Hoeven Neal; Glaser Laurel; Solórzano Alicia; Pappas Claudia; Cox Nancy J; Swayne David E; Palese Peter; Katz Jacqueline M; García-Sastre Adolfo
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission.
Science (New York, N.Y.) 2007;315(5812):655-9.
2007: Mayer Daniel; Molawi Kaaweh; Martínez-Sobrido Luis; Ghanem Alexander; Thomas Stefan; Baginsky Sacha; Grossmann Jonas; García-Sastre Adolfo; Schwemmle Martin
Identification of cellular interaction partners of the influenza virus ribonucleoprotein complex and polymerase complex using proteomic-based approaches.
Journal of proteome research 2007;6(2):672-82.
2007: Lenschow Deborah J; Lai Caroline; Frias-Staheli Natalia; Giannakopoulos Nadia V; Lutz Andrew; Wolff Thorsten; Osiak Anna; Levine Beth; Schmidt Robert E; García-Sastre Adolfo; Leib David A; Pekosz Andrew; Knobeloch Klaus-Peter; Horak Ivan; Virgin Herbert Whiting
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(4):1371-6.
2007: Basler Christopher F; García-Sastre Adolfo
Sensing RNA virus infections.
Nature chemical biology 2007;3(1):20-1.
2007: Mibayashi Masaki; Martínez-Sobrido Luis; Loo Yueh-Ming; Cárdenas Washington B; Gale Michael; García-Sastre Adolfo
Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus.
Journal of virology 2007;81(2):514-24.
2006: Wang Shixia; Taaffe Jessica; Parker Christopher; Solórzano Alicia; Cao Hong; García-Sastre Adolfo; Lu Shan
Hemagglutinin (HA) proteins from H1 and H3 serotypes of influenza A viruses require different antigen designs for the induction of optimal protective antibody responses as studied by codon-optimized HA DNA vaccines.
Journal of virology 2006;80(23):11628-37.
2006: Richt Jürgen A; Lekcharoensuk Porntippa; Lager Kelly M; Vincent Amy L; Loiacono Christina M; Janke Bruce H; Wu Wai-Hong; Yoon Kyoung-Jin; Webby Richard J; Solórzano Alicia; García-Sastre Adolfo
Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine.
Journal of virology 2006;80(22):11009-18.
2006: Baas T; Baskin C R; Diamond D L; García-Sastre A; Bielefeldt-Ohmann H; Tumpey T M; Thomas M J; Carter V S; Teal T H; Van Hoeven N; Proll S; Jacobs J M; Caldwell Z R; Gritsenko M A; Hukkanen R R; Camp D G; Smith R D; Katze M G
Integrated molecular signature of disease: analysis of influenza virus-infected macaques through functional genomics and proteomics.
Journal of virology 2006;80(21):10813-28.
2006: Kong Wing-Pui; Hood Chantelle; Yang Zhi-Yong; Wei Chih-Jen; Xu Ling; García-Sastre Adolfo; Tumpey Terrence M; Nabel Gary J
Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(43):15987-91.
2006: Kash John C; Tumpey Terrence M; Proll Sean C; Carter Victoria; Perwitasari Olivia; Thomas Matthew J; Basler Christopher F; Palese Peter; Taubenberger Jeffery K; García-Sastre Adolfo; Swayne David E; Katze Michael G
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus.
Nature 2006;443(7111):578-81.
2006: Martínez-Sobrido Luis; Zúñiga Elina I; Rosario Debralee; García-Sastre Adolfo; de la Torre Juan Carlos
Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus.
Journal of virology 2006;80(18):9192-9.
2006: Fernandez-Sesma Ana; Marukian Svetlana; Ebersole Barbara J; Kaminski Dorothy; Park Man-Seong; Yuen Tony; Sealfon Stuart C; García-Sastre Adolfo; Moran Thomas M
Influenza virus evades innate and adaptive immunity via the NS1 protein.
Journal of virology 2006;80(13):6295-304.
2006: Lowen Anice C; Mubareka Samira; Tumpey Terrence M; García-Sastre Adolfo; Palese Peter
The guinea pig as a transmission model for human influenza viruses.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(26):9988-92.
2006: Park Man-Seong; Steel John; García-Sastre Adolfo; Swayne David; Palese Peter
Engineered viral vaccine constructs with dual specificity: avian influenza and Newcastle disease.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8203-8.
2006: García-Sastre Adolfo; Biron Christine A
Type 1 interferons and the virus-host relationship: a lesson in détente .
Science (New York, N.Y.) 2006;312(5775):879-82.
2006: Glaser Laurel; Zamarin Dmitriy; Acland Helen M; Spackman Erica; Palese Peter; García-Sastre Adolfo; Tewari Deepanker
Sequence analysis and receptor specificity of the hemagglutinin of a recent influenza H2N2 virus isolated from chicken in North America.
Glycoconjugate journal 2006;23(1-2):93-9.
2006: Martinez-Sobrido Luis; Gitiban Negin; Fernandez-Sesma Ana; Cros Jerome; Mertz Sara E; Jewell Nancy A; Hammond Sue; Flano Emilio; Durbin Russell K; García-Sastre Adolfo; Durbin Joan E
Protection against respiratory syncytial virus by a recombinant Newcastle disease virus vector.
Journal of virology 2006;80(3):1130-9.
2006: García-Sastre Adolfo
Antiviral response in pandemic influenza viruses.
Emerging infectious diseases 2006;12(1):44-7.
2006: Efferson Clay L; Tsuda Naotake; Kawano Kouichiro; Nistal-Villán Estanislao; Sellappan Shankhar; Yu Dihua; Murray James L; García-Sastre Adolfo; Ioannides Constantin G
Prostate tumor cells infected with a recombinant influenza virus expressing a truncated NS1 protein activate cytolytic CD8+ cells to recognize noninfected tumor cells.
Journal of virology 2006;80(1):383-94.
2006: Carr Simon M; Carnero Elena; García-Sastre Adolfo; Brownlee George G; Fodor Ervin
Characterization of a mitochondrial-targeting signal in the PB2 protein of influenza viruses.
Virology 2006;344(2):492-508.
2005: Tumpey Terrence M; García-Sastre Adolfo; Taubenberger Jeffery K; Palese Peter; Swayne David E; Pantin-Jackwood Mary J; Schultz-Cherry Stacey; Solórzano Alicia; Van Rooijen Nico; Katz Jacqueline M; Basler Christopher F
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice.
Journal of virology 2005;79(23):14933-44.
2005: Tumpey Terrence M; Basler Christopher F; Aguilar Patricia V; Zeng Hui; Solórzano Alicia; Swayne David E; Cox Nancy J; Katz Jacqueline M; Taubenberger Jeffery K; Palese Peter; García-Sastre Adolfo
Characterization of the reconstructed 1918 Spanish influenza pandemic virus.
Science (New York, N.Y.) 2005;310(5745):77-80.
2005: Falcón Ana M; Fernandez-Sesma Ana; Nakaya Yurie; Moran Thomas M; Ortín Juan; García-Sastre Adolfo
Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins.
The Journal of general virology 2005;86(Pt 10):2817-21.
2005: Zamarin Dmitriy; García-Sastre Adolfo; Xiao Xiaoyao; Wang Rong; Palese Peter
Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1.
PLoS pathogens 2005;1(1):e4.
2005: Glaser Laurel; Stevens James; Zamarin Dmitriy; Wilson Ian A; García-Sastre Adolfo; Tumpey Terrence M; Basler Christopher F; Taubenberger Jeffery K; Palese Peter
A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity.
Journal of virology 2005;79(17):11533-6.
2005: Quinlivan Michelle; Zamarin Dmitriy; García-Sastre Adolfo; Cullinane Ann; Chambers Thomas; Palese Peter
Attenuation of equine influenza viruses through truncations of the NS1 protein.
Journal of virology 2005;79(13):8431-9.
2005: Muñoz-Jordán Jorge L; Laurent-Rolle Maudry; Ashour Joseph; Martínez-Sobrido Luis; Ashok Mundrigi; Lipkin W Ian; García-Sastre Adolfo
Inhibition of alpha/beta interferon signaling by the NS4B protein of flaviviruses.
Journal of virology 2005;79(13):8004-13.
2005: Bourmakina Svetlana V; García-Sastre Adolfo
The morphology and composition of influenza A virus particles are not affected by low levels of M1 and M2 proteins in infected cells.
Journal of virology 2005;79(12):7926-32.
2005: Solórzano Alicia; Webby Richard J; Lager Kelly M; Janke Bruce H; García-Sastre Adolfo; Richt Jürgen A
Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs.
Journal of virology 2005;79(12):7535-43.
2005: Bertolotti-Ciarlet Andrea; Smith Jonathan; Strecker Karin; Paragas Jason; Altamura Louis A; McFalls Jeanne M; Frias-Stäheli Natalia; García-Sastre Adolfo; Schmaljohn Connie S; Doms Robert W
Cellular localization and antigenic characterization of crimean-congo hemorrhagic fever virus glycoproteins.
Journal of virology 2005;79(10):6152-61.
2005: Efferson Clay L; Kawano Kouichiro; Tsuda Naotake; Palese Peter; García-Sastre Adolfo; Ioannides Constantin G
Stimulation of human T cells by an influenza A vector expressing a CTL epitope from the HER-2/neu protooncogene results in higher numbers of antigen-specific TCRhi cells than stimulation with peptide. Divergent roles of IL-2 and IL-15.
Anticancer research 2005;25(2A):715-24.
2005: Cros Jerome F; García-Sastre Adolfo; Palese Peter
An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein.
Traffic (Copenhagen, Denmark) 2005;6(3):205-13.
2005: Spiegel Martin; Pichlmair Andreas; Martínez-Sobrido Luis; Cros Jerome; García-Sastre Adolfo; Haller Otto; Weber Friedemann
Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3.
Journal of virology 2005;79(4):2079-86.
2005: Basler Christopher F; García-Sastre Adolfo; Palese Peter
A novel paramyxovirus?
Emerging infectious diseases 2005;11(1):108-12.
2005: Marcos Fernando; Ferreira Laura; Cros Jerome; Park Man-Seong; Nakaya Takaaki; García-Sastre Adolfo; Villar Enrique
Mapping of the RNA promoter of Newcastle disease virus.
Virology 2005;331(2):396-406.
2005: Jennings Stephanie; Martínez-Sobrido Luis; García-Sastre Adolfo; Weber Friedemann; Kochs Georg
Thogoto virus ML protein suppresses IRF3 function.
Virology 2005;331(1):63-72.
2004: Donelan Nicola R; Dauber Bianca; Wang Xiuyan; Basler Christopher F; Wolff Thorsten; García-Sastre Adolfo
The N- and C-terminal domains of the NS1 protein of influenza B virus can independently inhibit IRF-3 and beta interferon promoter activation.
Journal of virology 2004;78(21):11574-82.
2004: Baskin Carole R; García-Sastre Adolfo; Tumpey Terrence M; Bielefeldt-Ohmann Helle; Carter Victoria S; Nistal-Villán Estanislao; Katze Michael G
Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina).
Journal of virology 2004;78(19):10420-32.
2004: Kash John C; Basler Christopher F; García-Sastre Adolfo; Carter Victoria; Billharz Rosalind; Swayne David E; Przygodzki Ronald M; Taubenberger Jeffery K; Katze Michael G; Tumpey Terrence M
Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus.
Journal of virology 2004;78(17):9499-511.
2004: Nakaya Yurie; Nakaya Takaaki; Park Man-Seong; Cros Jerome; Imanishi Jiro; Palese Peter; García-Sastre Adolfo
Induction of cellular immune responses to simian immunodeficiency virus gag by two recombinant negative-strand RNA virus vectors.
Journal of virology 2004;78(17):9366-75.
2004: Vecino William H; Quanquin Natalie M; Martinez-Sobrido Luis; Fernandez-Sesma Ana; García-Sastre Adolfo; Jacobs William R; Fennelly Glenn J
Mucosal immunization with attenuated Shigella flexneri harboring an influenza hemagglutinin DNA vaccine protects mice against a lethal influenza challenge.
Virology 2004;325(2):192-9.
2004: Shaw Megan L; García-Sastre Adolfo; Palese Peter; Basler Christopher F
Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively.
Journal of virology 2004;78(11):5633-41.
2004: Ebert Oliver; Shinozaki Katsunori; Kournioti Chryssanthi; Park Man-Seong; García-Sastre Adolfo; Woo Savio L C
Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer.
Cancer research 2004;64(9):3265-70.
2004: Muster Thomas; Rajtarova Julia; Sachet Monika; Unger Hermann; Fleischhacker Reinhard; Romirer Ingrid; Grassauer Andreas; Url Angelika; García-Sastre Adolfo; Wolff Klaus; Pehamberger Hubert; Bergmann Michael
Interferon resistance promotes oncolysis by influenza virus NS1-deletion mutants.
International journal of cancer. Journal international du cancer 2004;110(1):15-21.
2004: Tumpey Terrence M; García-Sastre Adolfo; Taubenberger Jeffery K; Palese Peter; Swayne David E; Basler Christopher F
Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3166-71.
2004: Li Wan-Xiang; Li Hongwei; Lu Rui; Li Feng; Dus Monica; Atkinson Peter; Brydon Edward W A; Johnson Kyle L; García-Sastre Adolfo; Ball L Andrew; Palese Peter; Ding Shou-Wei
Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1350-5.
2004: García-Sastre A
Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses.
Current topics in microbiology and immunology 2004;283():249-80.
2003: Miyahira Yasushi; Akiba Hisaya; Katae Masaharu; Kubota Kaori; Kobayashi Seiki; Takeuchi Tsutomu; García-Sastre Adolfo; Fukuchi Yoshinosuke; Okumura Ko; Yagita Hideo; Aoki Takashi
Cutting edge: a potent adjuvant effect of ligand to receptor activator of NF-kappa B gene for inducing antigen-specific CD8+ T cell response by DNA and viral vector vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6344-8.
2003: Donelan Nicola R; Basler Christopher F; García-Sastre Adolfo
A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice.
Journal of virology 2003;77(24):13257-66.
2003: Muñoz-Jordan Jorge L; Sánchez-Burgos Gilma G; Laurent-Rolle Maudry; García-Sastre Adolfo
Inhibition of interferon signaling by dengue virus.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14333-8.
2003: González-Aseguinolaza Gloria; Nakaya Yurie; Molano Alberto; Dy Edward; Esteban Mariano; Rodríguez Dolores; Rodríguez Juan Ramón; Palese Peter; García-Sastre Adolfo; Nussenzweig Ruth S
Induction of protective immunity against malaria by priming-boosting immunization with recombinant cold-adapted influenza and modified vaccinia Ankara viruses expressing a CD8+-T-cell epitope derived from the circumsporozoite protein of Plasmodium yoelii.
Journal of virology 2003;77(21):11859-66.
2003: Huang Tian-Gui; Ebert Oliver; Shinozaki Katsunori; García-Sastre Adolfo; Woo Savio L C
Oncolysis of hepatic metastasis of colorectal cancer by recombinant vesicular stomatitis virus in immune-competent mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(3):434-40.
2003: Park Man-Seong; García-Sastre Adolfo; Cros Jerome F; Basler Christopher F; Palese Peter
Newcastle disease virus V protein is a determinant of host range restriction.
Journal of virology 2003;77(17):9522-32.
2003: Flandorfer Astrid; García-Sastre Adolfo; Basler Christopher F; Palese Peter
Chimeric influenza A viruses with a functional influenza B virus neuraminidase or hemagglutinin.
Journal of virology 2003;77(17):9116-23.
2003: Ebert Oliver; Shinozaki Katsunori; Huang Tian-Gui; Savontaus Mikko J; García-Sastre Adolfo; Woo Savio L C
Oncolytic vesicular stomatitis virus for treatment of orthotopic hepatocellular carcinoma in immune-competent rats.
Cancer research 2003;63(13):3605-11.
2003: Basler Christopher F; Mikulasova Andrea; Martinez-Sobrido Luis; Paragas Jason; Mühlberger Elke; Bray Mike; Klenk Hans-Dieter; Palese Peter; García-Sastre Adolfo
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
Journal of virology 2003;77(14):7945-56.
2003: Efferson Clay L; Schickli Jeanne; Ko Byung Kyum; Kawano Kouichiro; Mouzi Sara; Palese Peter; García-Sastre Adolfo; Ioannides Constantin G
Activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs) by human dendritic cells infected with an attenuated influenza A virus expressing a CTL epitope derived from the HER-2/neu proto-oncogene.
Journal of virology 2003;77(13):7411-24.
2003: Gherardi M Magdalena; Nájera José Luis; Pérez-Jiménez Eva; Guerra Susana; García-Sastre Adolfo; Esteban Mariano
Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes.
Journal of virology 2003;77(12):7048-57.
2003: Huarte Maite; Falcón Ana; Nakaya Yuri; Ortín Juan; García-Sastre Adolfo; Nieto Amelia
Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses.
Journal of virology 2003;77(10):6007-13.
2003: Nakaya Yurie; Zheng Hongyong; García-Sastre Adolfo
Enhanced cellular immune responses to SIV Gag by immunization with influenza and vaccinia virus recombinants.
Vaccine 2003;21(17-18):2097-106.
2003: López Carolina B; García-Sastre Adolfo; Williams Bryan R G; Moran Thomas M
Type I interferon induction pathway, but not released interferon, participates in the maturation of dendritic cells induced by negative-strand RNA viruses.
The Journal of infectious diseases 2003;187(7):1126-36.
2003: Bourmakina Svetlana V; García-Sastre Adolfo
Reverse genetics studies on the filamentous morphology of influenza A virus.
The Journal of general virology 2003;84(Pt 3):517-27.
2003: Park Man-Seong; Shaw Megan L; Muñoz-Jordan Jorge; Cros Jerome F; Nakaya Takaaki; Bouvier Nicole; Palese Peter; García-Sastre Adolfo; Basler Christopher F
Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins.
Journal of virology 2003;77(2):1501-11.
2003: Chesler David A; Muñoz-Jordán Jorge Luis; Donelan Nicola; García-Sastre Adolfo; Reiss Carol Shoshkes
PKR is not required for interferon-gamma inhibition of VSV replication in neurons.
Viral immunology 2003;16(1):87-96.
2002: Wang Xiuyan; Basler Christopher F; Williams Bryan R G; Silverman Robert H; Palese Peter; García-Sastre Adolfo
Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.
Journal of virology 2002;76(24):12951-62.
2002: Ludwig Stephan; Wang Xiuyan; Ehrhardt Christina; Zheng Hongyong; Donelan Nicola; Planz Oliver; Pleschka Stephan; García-Sastre Adolfo; Heins Gudrun; Wolff Thorsten
The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors.
Journal of virology 2002;76(21):11166-71.
2002: Tumpey Terrence M; García-Sastre Adolfo; Mikulasova Andrea; Taubenberger Jeffery K; Swayne David E; Palese Peter; Basler Christopher F
Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13849-54.
2002: Palese Peter; Basler Christopher F; García-Sastre Adolfo
The makings of a killer.
Nature medicine 2002;8(9):927-8.
2002: Yewdell Jonathan; García-Sastre Adolfo
Influenza virus still surprises.
Current opinion in microbiology 2002;5(4):414-8.
2002: Geiss Gary K; Salvatore Mirella; Tumpey Terrence M; Carter Victoria S; Wang Xiuyan; Basler Christopher F; Taubenberger Jeffery K; Bumgarner Roger E; Palese Peter; Katze Michael G; García-Sastre Adolfo
Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10736-41.
2002: Basler Christopher F; García-Sastre Adolfo
Viruses and the type I interferon antiviral system: induction and evasion.
International reviews of immunology 2002;21(4-5):305-37.
2002: Palese Peter; García-Sastre Adolfo
Influenza vaccines: present and future.
The Journal of clinical investigation 2002;110(1):9-13.
2002: Palese Peter; García-Sastre Adolfo
New directions in vaccine research.
The Journal of clinical investigation 2002;109(12):1517-8.
2002: García-Sastre Adolfo
Mechanisms of inhibition of the host interferon alpha/beta-mediated antiviral responses by viruses.
Microbes and infection / Institut Pasteur 2002;4(6):647-55.
2002: Mora Rosalia; Rodriguez-Boulan Enrique; Palese Peter; García-Sastre Adolfo
Apical budding of a recombinant influenza A virus expressing a hemagglutinin protein with a basolateral localization signal.
Journal of virology 2002;76(7):3544-53.
2002: Salvatore Mirella; Basler Christopher F; Parisien Jean-Patrick; Horvath Curt M; Bourmakina Svetlana; Zheng Hongyong; Muster Thomas; Palese Peter; García-Sastre Adolfo
Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis.
Journal of virology 2002;76(3):1206-12.
2001: Schickli J H; Flandorfer A; Nakaya T; Martinez-Sobrido L; García-Sastre A; Palese P
Plasmid-only rescue of influenza A virus vaccine candidates.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001;356(1416):1965-73.
2001: Nakaya T; Cros J; Park M S; Nakaya Y; Zheng H; Sagrera A; Villar E; García-Sastre A; Palese P
Recombinant Newcastle disease virus as a vaccine vector.
Journal of virology 2001;75(23):11868-73.
2001: Bergmann M; Romirer I; Sachet M; Fleischhacker R; García-Sastre A; Palese P; Wolff K; Pehamberger H; Jakesz R; Muster T
A genetically engineered influenza A virus with ras-dependent oncolytic properties.
Cancer research 2001;61(22):8188-93.
2001: Paragas J; Talon J; O'Neill R E; Anderson D K; García-Sastre A; Palese P
Influenza B and C virus NEP (NS2) proteins possess nuclear export activities.
Journal of virology 2001;75(16):7375-83.
2001: Levy D E; García-Sastre A
The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion.
Cytokine & growth factor reviews 2001;12(2-3):143-56.
2001: Sagrera A; Cobaleda C; González De Buitrago J M; García-Sastre A; Villar E
Membrane glycoproteins of Newcastle disease virus: nucleotide sequence of the hemagglutinin-neuraminidase cloned gene and structure/function relationship of predicted amino acid sequence.
Glycoconjugate journal 2001;18(4):283-9.
2001: Smith E J; Marié I; Prakash A; García-Sastre A; Levy D E
IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein.
The Journal of biological chemistry 2001;276(12):8951-7.
2001: Basler C F; Reid A H; Dybing J K; Janczewski T A; Fanning T G; Zheng H; Salvatore M; Perdue M L; Swayne D E; García-Sastre A; Palese P; Taubenberger J K
Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2746-51.
2001: García-Sastre A
Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses.
Virology 2001;279(2):375-84.
2000: Zheng H; Palese P; García-Sastre A
Antitumor properties of influenza virus vectors.
Cancer research 2000;60(24):6972-6.
2000: Wang X; Li M; Zheng H; Muster T; Palese P; Beg A A; García-Sastre A
Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon.
Journal of virology 2000;74(24):11566-73.
2000: Basler C F; Wang X; Mühlberger E; Volchkov V; Paragas J; Klenk H D; García-Sastre A; Palese P
The Ebola virus VP35 protein functions as a type I IFN antagonist.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12289-94.
2000: Talon J; Horvath C M; Polley R; Basler C F; Muster T; Palese P; García-Sastre A
Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein.
Journal of virology 2000;74(17):7989-96.
2000: Durbin J E; Fernandez-Sesma A; Lee C K; Rao T D; Frey A B; Moran T M; Vukmanovic S; García-Sastre A; Levy D E
Type I IFN modulates innate and specific antiviral immunity.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(8):4220-8.
2000: Gilleland H E; Gilleland L B; Staczek J; Harty R N; García-Sastre A; Palese P; Brennan F R; Hamilton W D; Bendahmane M; Beachy R N
Chimeric animal and plant viruses expressing epitopes of outer membrane protein F as a combined vaccine against Pseudomonas aeruginosa lung infection.
FEMS immunology and medical microbiology 2000;27(4):291-7.
2000: Talon J; Salvatore M; O'Neill R E; Nakaya Y; Zheng H; Muster T; García-Sastre A; Palese P
Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4309-14.
2000: Solorzano A; Zheng H; Fodor E; Brownlee G G; Palese P; García-Sastre A
Reduced levels of neuraminidase of influenza A viruses correlate with attenuated phenotypes in mice.
The Journal of general virology 2000;81(Pt 3):737-42.
1999: Fodor E; Devenish L; Engelhardt O G; Palese P; Brownlee G G; García-Sastre A
Rescue of influenza A virus from recombinant DNA.
Journal of virology 1999;73(11):9679-82.
1999: Basler C F; García-Sastre A; Palese P
Mutation of neuraminidase cysteine residues yields temperature-sensitive influenza viruses.
Journal of virology 1999;73(10):8095-103.
1999: Zheng H; Lee H A; Palese P; García-Sastre A
Influenza A virus RNA polymerase has the ability to stutter at the polyadenylation site of a viral RNA template during RNA replication.
Journal of virology 1999;73(6):5240-3.
1999: Gonzalo R M; Rodríguez D; García-Sastre A; Rodríguez J R; Palese P; Esteban M
Enhanced CD8+ T cell response to HIV-1 env by combined immunization with influenza and vaccinia virus recombinants.
Vaccine 1999;17(7-8):887-92.
1998: García-Sastre A; Egorov A; Matassov D; Brandt S; Levy D E; Durbin J E; Palese P; Muster T
Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems.
Virology 1998;252(2):324-30.
1998: García-Sastre A; Durbin R K; Zheng H; Palese P; Gertner R; Levy D E; Durbin J E
The role of interferon in influenza virus tissue tropism.
Journal of virology 1998;72(11):8550-8.
1998: Staczek J; Gilleland H E; Gilleland L B; Harty R N; García-Sastre A; Engelhardt O G; Palese P
A chimeric influenza virus expressing an epitope of outer membrane protein F of Pseudomonas aeruginosa affords protection against challenge with P. aeruginosa in a murine model of chronic pulmonary infection.
Infection and immunity 1998;66(8):3990-4.
1998: Fodor E; Palese P; Brownlee G G; García-Sastre A
Attenuation of influenza A virus mRNA levels by promoter mutations.
Journal of virology 1998;72(8):6283-90.
1998: García-Sastre A
Negative-strand RNA viruses: applications to biotechnology.
Trends in biotechnology 1998;16(5):230-5.
1998: Miyahira Y; García-Sastre A; Rodriguez D; Rodriguez J R; Murata K; Tsuji M; Palese P; Esteban M; Zavala F; Nussenzweig R S
Recombinant viruses expressing a human malaria antigen can elicit potentially protective immune CD8+ responses in mice.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3954-9.
1998: Bot A; Bot S; García-Sastre A; Bona C
Protective cellular immunity against influenza virus induced by plasmid inoculation of newborn mice.
Developmental immunology 1998;5(3):197-210.
1997: Palese P; Zavala F; Muster T; Nussenzweig R S; García-Sastre A
Development of novel influenza virus vaccines and vectors.
The Journal of infectious diseases 1997;176 Suppl 1():S45-9.
1996: Palese P; Zheng H; Engelhardt O G; Pleschka S; García-Sastre A
Negative-strand RNA viruses: genetic engineering and applications.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11354-8.
1996: Pleschka S; Jaskunas R; Engelhardt O G; Zürcher T; Palese P; García-Sastre A
A plasmid-based reverse genetics system for influenza A virus.
Journal of virology 1996;70(6):4188-92.
1996: Zheng H; Palese P; García-Sastre A
Nonconserved nucleotides at the 3' and 5' ends of an influenza A virus RNA play an important role in viral RNA replication.
Virology 1996;217(1):242-51.
1995: García-Sastre A; Palese P
Influenza virus vectors.
Biologicals : journal of the International Association of Biological Standardization 1995;23(2):171-8.
1995: García-Sastre A; Palese P
The cytoplasmic tail of the neuraminidase protein of influenza A virus does not play an important role in the packaging of this protein into viral envelopes.
Virus research 1995;37(1):37-47.
1994: García-Sastre A; Muster T; Barclay W S; Percy N; Palese P
Use of a mammalian internal ribosomal entry site element for expression of a foreign protein by a transfectant influenza virus.
Journal of virology 1994;68(10):6254-61.
1994: Percy N; Barclay W S; García-Sastre A; Palese P
Expression of a foreign protein by influenza A virus.
Journal of virology 1994;68(7):4486-92.
1994: García-Sastre A; Percy N; Barclay W; Palese P
Introduction of foreign sequences into the genome of influenza A virus.
Developments in biological standardization 1994;82():237-46.
1993: García-Sastre A; Palese P
Genetic manipulation of negative-strand RNA virus genomes.
Annual review of microbiology 1993;47():765-90.
1992: Bergmann M; García-Sastre A; Palese P
Transfection-mediated recombination of influenza A virus.
Journal of virology 1992;66(12):7576-80.

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