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Elsa Garcin

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Chemicals & Drugs

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TOP 3
Zhi-Wen Guan; Mohammad Mahfuzul Haque; Chin-Chuan Wei; Elsa D Garcin; Elizabeth D Getzoff; Dennis J Stuehr
Lys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin binding, increase FMN shielding, and suppress interflavin electron transfer.
Elsa D Garcin; Andrew S Arvai; Robin J Rosenfeld; Matt D Kroeger; Brian R Crane; Gunilla Andersson; Glen Andrews; Peter J Hamley; Philip R Mallinder; David J Nicholls; Stephen A St-Gallay; Alan C Tinker; Nigel P Gensmantel; Antonio Mete; David R Cheshire; Stephen Connolly; Dennis J Stuehr; Anders Aberg; Alan V Wallace; John A Tainer; Elizabeth D Getzoff
Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Elsa D Garcin; David J Hosfield; Brenda Osborne; Brian J Haas; Magnar Björas; Richard P Cunningham; John A Tainer
DNA apurinic-apyrimidinic site binding and excision by endonuclease IV.

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All Publications

2010: Zhi-Wen Guan; Mohammad Mahfuzul Haque; Chin-Chuan Wei; Elsa D Garcin; Elizabeth D Getzoff; Dennis J Stuehr
Lys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin binding, increase FMN shielding, and suppress interflavin electron transfer.
The Journal of biological chemistry 2010;285(5):3064-75.
2008: Elsa D Garcin; Andrew S Arvai; Robin J Rosenfeld; Matt D Kroeger; Brian R Crane; Gunilla Andersson; Glen Andrews; Peter J Hamley; Philip R Mallinder; David J Nicholls; Stephen A St-Gallay; Alan C Tinker; Nigel P Gensmantel; Antonio Mete; David R Cheshire; Stephen Connolly; Dennis J Stuehr; Anders Aberg; Alan V Wallace; John A Tainer; Elizabeth D Getzoff
Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nature chemical biology 2008;4(11):700-7.
2008: Elsa D Garcin; David J Hosfield; Brenda Osborne; Brian J Haas; Magnar Björas; Richard P Cunningham; John A Tainer
DNA apurinic-apyrimidinic site binding and excision by endonuclease IV.
Nature structural & molecular biology 2008;15(5):515-22.
2005: Mauro Tiso; David W Konas; Koustubh Panda; Elsa D Garcin; Manisha Sharma; Elizabeth D Getzoff; Dennis J Stuehr
C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase.
The Journal of biological chemistry 2005;280(47):39208-19.
2005: Chin-Chuan Wei; Zhi-Qiang Wang; Deborah Durra; Craig Hemann; Russ Hille; Elsa D Garcin; Elizabeth D Getzoff; Dennis J Stuehr
The three nitric-oxide synthases differ in their kinetics of tetrahydrobiopterin radical formation, heme-dioxy reduction, and arginine hydroxylation.
The Journal of biological chemistry 2005;280(10):8929-35.
2004: Elsa D Garcin; Christopher M Bruns; Sarah J Lloyd; David J Hosfield; Mauro Tiso; Ratan Gachhui; Dennis J Stuehr; John A Tainer; Elizabeth D Getzoff
Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase.
The Journal of biological chemistry 2004;279(36):37918-27.
2002: Robin J Rosenfeld; Elsa D Garcin; Koustubh Panda; Gunilla Andersson; Anders Aberg; Alan V Wallace; Garrett M Morris; Arthur J Olson; Dennis J Stuehr; John A Tainer; Elizabeth D Getzoff
Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency.
Biochemistry 2002;41(47):13915-25.