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Luis Gardell

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Luis R Gardell; Jian-Nong Ma; Jimmi Gerner Seitzberg; Anne E Knapp; Hans H Schiffer; Ali Tabatabaei; Christopher N Davis; Michelle Owens; Bryan Clemons; Kenneth K Wong; Birgitte Lund; Norman R Nash; Yan Gao; Jelveh Lameh; Kara Schmelzer; Roger Olsson; Ethan S Burstein
Identification and characterization of novel small-molecule protease-activated receptor 2 agonists.
Beatriz Fioravanti; Milena De Felice; Cheryl L Stucky; Karen A Medler; Miaw-Chyi Luo; Luis R Gardell; mukwaya Ibrahim; T Philip Malan; Henry I Yamamura; Michael H Ossipov; Tamara King; Josephine Lai; Frank Porreca; Todd W Vanderah
Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists.
Luis R Gardell; Lene Hyldtoft; Andria L Del Tredici; Carsten B Andersen; Luke C Fairbairn; Birgitte W Lund; Magnus Gustafsson; Mark R Brann; Roger Olsson; Fabrice Piu
Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist.

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2008: Luis R Gardell; Jian-Nong Ma; Jimmi Gerner Seitzberg; Anne E Knapp; Hans H Schiffer; Ali Tabatabaei; Christopher N Davis; Michelle Owens; Bryan Clemons; Kenneth K Wong; Birgitte Lund; Norman R Nash; Yan Gao; Jelveh Lameh; Kara Schmelzer; Roger Olsson; Ethan S Burstein
Identification and characterization of novel small-molecule protease-activated receptor 2 agonists.
The Journal of pharmacology and experimental therapeutics 2008;327(3):799-808.
2008: Beatriz Fioravanti; Milena De Felice; Cheryl L Stucky; Karen A Medler; Miaw-Chyi Luo; Luis R Gardell; mukwaya Ibrahim; T Philip Malan; Henry I Yamamura; Michael H Ossipov; Tamara King; Josephine Lai; Frank Porreca; Todd W Vanderah
Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(45):11593-602.
2008: Luis R Gardell; Lene Hyldtoft; Andria L Del Tredici; Carsten B Andersen; Luke C Fairbairn; Birgitte W Lund; Magnus Gustafsson; Mark R Brann; Roger Olsson; Fabrice Piu
Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist.
European journal of pharmacology 2008;592(1-3):158-9.
2008: Fabrice Piu; Cindy Cheevers; Lene Hyldtoft; Luis R Gardell; Andria L Del Tredici; Carsten B Andersen; Luke C Fairbairn; Birgitte W Lund; Magnus Gustafsson; Hans H Schiffer; John E Donello; Roger Olsson; Daniel W Gil; Mark R Brann
Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist.
European journal of pharmacology 2008;590(1-3):423-9.
2008: Fabrice Piu; Luis R Gardell; Thomas Son; Nathalie Schlienger; Birgitte W Lund; Hans H Schiffer; Kim E Vanover; Robert E Davis; Roger Olsson; Stefania Risso Bradley
Pharmacological characterization of AC-262536, a novel selective androgen receptor modulator.
The Journal of steroid biochemistry and molecular biology 2008;109(1-2):129-37.
2007: Michael H Ossipov; Igor Bazov; Luis R Gardell; Justin Kowal; Tatiana Yakovleva; Ivan Usynin; Tomas J Ekström; Frank Porreca; Georgy Bakalkin
Control of chronic pain by the ubiquitin proteasome system in the spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(31):8226-37.
2007: Luis R Gardell; Kimberly E Vanover; Linda Pounds; Robert W Johnson; Richard Barido; Gary T Anderson; isaac veinbergs; Agnete Dyssegaard; Per Brunmark; Ali Tabatabaei; Robert E Davis; Mark R Brann; Uli Hacksell; Douglas W Bonhaus
ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models.
The Journal of pharmacology and experimental therapeutics 2007;322(2):862-70.
2007: Jian-Nong Ma; Hans H Schiffer; Anne E Knapp; Jean Wang; Kenneth K Wong; Erika A Currier; Michelle Owens; Norman R Nash; Luis R Gardell; Mark R Brann; Roger Olsson; Ethan S Burstein
Identification of the atypical L-type Ca2+ channel blocker diltiazem and its metabolites as ghrelin receptor agonists.
Molecular pharmacology 2007;72(2):380-6.
2006: Josephine Lai; Miaw-Chyi Luo; Qingmin Chen; Shouwu Ma; Luis R Gardell; Michael H Ossipov; Frank Porreca
Dynorphin A activates bradykinin receptors to maintain neuropathic pain.
Nature neuroscience 2006;9(12):1534-40.
2006: Kimberly E Vanover; David M Weiner; Malath Makhay; isaac veinbergs; Luis R Gardell; Jelveh Lameh; Andria L Del Tredici; Fabrice Piu; Hans H Schiffer; Thomas R Ott; Ethan S Burstein; Allan K Uldam; Mikkel B Thygesen; Nathalie Schlienger; Carl Magnus Andersson; Thomas Y Son; Scott C Harvey; Susan B Powell; Mark A Geyer; Bo-Ragnar Tolf; Mark R Brann; Robert E Davis
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.
The Journal of pharmacology and experimental therapeutics 2006;317(2):910-8.
2006: Luis R Gardell; Tamara King; Michael H Ossipov; Kenner C Rice; Josephine Lai; Todd W Vanderah; Frank Porreca
Opioid receptor-mediated hyperalgesia and antinociceptive tolerance induced by sustained opiate delivery.
Neuroscience letters 2006;396(1):44-9.
2005: Tamara King; Luis R Gardell; Ruizhong Wang; Anna Vardanyan; Michael H Ossipov; T Philip Malan; Todd W Vanderah; Stephen P Hunt; Victor J Hruby; Josephine Lai; Frank Porreca
Role of NK-1 neurotransmission in opioid-induced hyperalgesia.
Pain 2005;116(3):276-88.
2005: Jennifer Y Xie; David Herman; Carl-Olav Stiller; Luis R Gardell; Michael H Ossipov; Josephine Lai; Frank Porreca; Todd W Vanderah
Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(2):409-16.
2004: Luis R Gardell; mukwaya Ibrahim; Ruizhong Wang; Zaijie Jim Wang; Michael H Ossipov; T Philip Malan; Frank Porreca; Josephine Lai
Mouse strains that lack spinal dynorphin upregulation after peripheral nerve injury do not develop neuropathic pain.
Neuroscience 2004;123(1):43-52.
2003: Luis R Gardell; Ruizhong Wang; Chris Ehrenfels; Michael H Ossipov; Anthony J Rossomando; Stephan Miller; Carolyn Buckley; Amber K Cai; Albert Tse; Susan F Foley; BangJian Gong; Lee Walus; Paul Carmillo; Dane Worley; Carol Huang; Thomas Engber; Blake Pepinsky; Richard L Cate; Todd W Vanderah; Josephine Lai; Dinah W Y Sah; Frank Porreca
Multiple actions of systemic artemin in experimental neuropathy.
Nature medicine 2003;9(11):1383-9.
2003: Luis R Gardell; Todd W Vanderah; S E Gardell; Ruizhong Wang; Michael H Ossipov; Josephine Lai; Frank Porreca
Enhanced evoked excitatory transmitter release in experimental neuropathy requires descending facilitation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(23):8370-9.
2003: Ahmet Dogrul; Luis R Gardell; Michael H Ossipov; F Cankat Tulunay; Josephine Lai; Frank Porreca
Reversal of experimental neuropathic pain by T-type calcium channel blockers.
Pain 2003;105(1-2):159-68.
2002: Luis R Gardell; Michael H Ossipov; Todd W Vanderah; Josephine Lai; Frank Porreca
Dynorphin-independent spinal cannabinoid antinociception.
Pain 2002;100(3):243-8.
2002: Michael H Ossipov; En-Tan Zhang; Cristina Carvajal; Luis R Gardell; Rémi Quirion; Yvan Dumont; Josephine Lai; Frank Porreca
Selective mediation of nerve injury-induced tactile hypersensitivity by neuropeptide Y.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(22):9858-67.
2002: Ahmet Dogrul; Luis R Gardell; Shouwu Ma; Michael H Ossipov; Frank Porreca; Josephine Lai
'Knock-down' of spinal CB1 receptors produces abnormal pain and elevates spinal dynorphin content in mice.
Pain 2002;100(1-2):203-9.
2002: Luis R Gardell; Ruizhong Wang; Shannon E Burgess; Michael H Ossipov; Todd W Vanderah; T Philip Malan; Josephine Lai; Frank Porreca
Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(15):6747-55.
2002: Luis R Gardell; Shannon E Burgess; Ahmet Dogrul; Michael H Ossipov; T Philip Malan; Josephine Lai; Frank Porreca
Pronociceptive effects of spinal dynorphin promote cannabinoid-induced pain and antinociceptive tolerance.
Pain 2002;98(1-2):79-88.
2002: Shannon E Burgess; Luis R Gardell; Michael H Ossipov; T Philip Malan; Todd W Vanderah; Josephine Lai; Frank Porreca
Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(12):5129-36.
2001: Frank Porreca; Shannon E Burgess; Luis R Gardell; Todd W Vanderah; T Philip Malan; Michael H Ossipov; D A Lappi; Josephine Lai
Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(14):5281-8.
2001: Zaijie Jim Wang; Luis R Gardell; Michael H Ossipov; Todd W Vanderah; Miles B Brennan; Ute Hochgeschwender; Victor J Hruby; T Philip Malan; Josephine Lai; Frank Porreca
Pronociceptive actions of dynorphin maintain chronic neuropathic pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(5):1779-86.
2000: Todd W Vanderah; Luis R Gardell; Shannon E Burgess; mukwaya Ibrahim; Ahmet Dogrul; C M Zhong; En-Tan Zhang; T Philip Malan; Michael H Ossipov; Josephine Lai; Frank Porreca
Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):7074-9.
2000: T Philip Malan; Michael H Ossipov; Luis R Gardell; mukwaya Ibrahim; Di Bian; Josephine Lai; Frank Porreca
Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats.
Pain 2000;86(1-2):185-94.
1999: Luis R Gardell; Meta L Reid; C A Cavallero; Shannon E Burgess; R F Wallace; Christopher L Hubbell; Larry D Reid
Amlodipine, a calcium channel inhibitor, and cocaine and ethanol's reinforcing effects.
Pharmacology, biochemistry, and behavior 1999;64(3):567-72.
1998: Luis R Gardell; C A Whalen; M D Chambers; Karen J Boswell; Christopher L Hubbell; Larry D Reid
Valproate reduces intake of alcoholic beverage among rats.
Behavioural pharmacology 1998;9(8):683-9.
1998: CM Cramer; Luis R Gardell; KL Boedeker; J R Harris; Christopher L Hubbell; Larry D Reid
Isradipine combined with naltrexone persistently reduces the reward-relevant effects of cocaine and alcohol.
Pharmacology, biochemistry, and behavior 1998;60(2):345-56.
1997: Luis R Gardell; Larry D Reid; KL Boedeker; T M Liakos; Christopher L Hubbell
Isradipine and naltrexone in combination with isradipine interact with a period of abstinence to reduce rats' intakes of an alcoholic beverage.
Alcoholism, clinical and experimental research 1997;21(9):1592-8.
1997: Luis R Gardell; C A Whalen; S Chattophadyay; C A Cavallaro; Christopher L Hubbell; Larry D Reid
Combination of naltrexone and fluoxetine on rats' propensity to take alcoholic beverage.
Alcoholism, clinical and experimental research 1997;21(8):1435-9.
1996: Larry D Reid; Luis R Gardell; S Chattopadhyay; Christopher L Hubbell
Periodic naltrexone and propensity to take alcoholic beverage.
Alcoholism, clinical and experimental research 1996;20(8):1329-34.
1996: Luis R Gardell; Christopher L Hubbell; Larry D Reid
Naltrexone persistently reduces rats' intake of a palatable alcoholic beverage.
Alcoholism, clinical and experimental research 1996;20(3):584-8.