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William Applegate

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Robert P Byington; Curt D Furberg; David M Herrington; J Alan Herd; Donald B Hunninghake; Maureen H Lowery; Ward A Riley; Timothy E Craven; Lily Chaput; Christine C Ireland; William B Applegate
Effect of estrogen plus progestin on progression of carotid atherosclerosis in postmenopausal women with heart disease: HERS B-mode substudy.
William B Applegate
Elderly patients' adherence to statin therapy.
Grant W Somes; Stephen B Kritchevsky; Ronald I Shorr; Marco Pahor; William B Applegate
Body mass index, weight change, and death in older adults: the systolic hypertension in the elderly program.

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2002: Robert P Byington; Curt D Furberg; David M Herrington; J Alan Herd; Donald B Hunninghake; Maureen H Lowery; Ward A Riley; Timothy E Craven; Lily Chaput; Christine C Ireland; William B Applegate
Effect of estrogen plus progestin on progression of carotid atherosclerosis in postmenopausal women with heart disease: HERS B-mode substudy.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(10):1692-7.
2002: William B Applegate
Elderly patients' adherence to statin therapy.
JAMA : the journal of the American Medical Association 2002;288(4):495-7.
2002: Grant W Somes; Stephen B Kritchevsky; Ronald I Shorr; Marco Pahor; William B Applegate
Body mass index, weight change, and death in older adults: the systolic hypertension in the elderly program.
American journal of epidemiology 2002;156(2):132-8.
2002: Mauro Di Bari; Marco Pahor; M Barnard; N Gades; Marshall J Graney; Lonneke V van de Poll-Franse; Brenda W J H Penninx; N Marchionni; William B Applegate
Evaluation and correction for a 'training effect' in the cognitive assessment of older adults.
Neuroepidemiology 2002;21(2):87-92.
2002: Brenda W J H Penninx; W Jack Rejeski; Jasma Pandya; Michael E Miller; Mauro Di Bari; William B Applegate; Marco Pahor
Exercise and depressive symptoms: a comparison of aerobic and resistance exercise effects on emotional and physical function in older persons with high and low depressive symptomatology.
The journals of gerontology. Series B, Psychological sciences and social sciences 2002;57(2):P124-32.
2002: Marco Pahor; Lonneke V van de Poll-Franse; Steven R Deitcher; William Cushman; Karen C Johnson; Ronald I Shorr; Kandice Kottke-Marchant; Russell P Tracy; Grant W Somes; William B Applegate
Fosinopril versus amlodipine comparative treatments study: a randomized trial to assess effects on plasminogen activator inhibitor-1.
Circulation 2002;105(4):457-61.
2002: William B Applegate
JAGS Approaches Middle Age with a Growth Spurt!
Journal of the American Geriatrics Society 2002;50(1):7-8.
2001: Brenda W J H Penninx; Stephen P Messier; W Jack Rejeski; Jeff D Williamson; M DiBari; C Cavazzini; William B Applegate; Marco Pahor
Physical exercise and the prevention of disability in activities of daily living in older persons with osteoarthritis.
Archives of internal medicine 2001;161(19):2309-16.
2001: Luigi Ferrucci; Curt D Furberg; Brenda W J H Penninx; M DiBari; Jeff D Williamson; Jack M Guralnik; J G Chen; William B Applegate; Marco Pahor
Treatment of isolated systolic hypertension is most effective in older patients with high-risk profile.
Circulation 2001;104(16):1923-6.
2001: M Pahor; B M Psaty; Michael H Alderman; William B Applegate; Curt D Furberg
Blood-pressure-lowering treatment.
Lancet 2001;358(9276):152-3.
2001: Jane A Cauley; D M Black; Elizabeth Barrett-Connor; F Harris; K Shields; William B Applegate; Steven R Cummings
Effects of hormone replacement therapy on clinical fractures and height loss: The Heart and Estrogen/Progestin Replacement Study (HERS).
The American journal of medicine 2001;110(6):442-50.
2001: Mauro Di Bari; Marco Pahor; Lonneke V van de Poll-Franse; Ronald I Shorr; Jim Y Wan; Luigi Ferrucci; Grant W Somes; William B Applegate
Dementia and disability outcomes in large hypertension trials: lessons learned from the systolic hypertension in the elderly program (SHEP) trial.
American journal of epidemiology 2001;153(1):72-8.
2001: Deborah Grady; Jeanette S Brown; Eric Vittinghoff; William B Applegate; E Varner; T Snyder
Postmenopausal hormones and incontinence: the Heart and Estrogen/Progestin Replacement Study.
Obstetrics and gynecology 2001;97(1):116-20.
2000: Marco Pahor; Bruce M Psaty; Michael H Alderman; William B Applegate; Jeff D Williamson; C Cavazzini; Curt D Furberg
Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: a meta-analysis of randomised controlled trials.
Lancet 2000;356(9246):1949-54.
2000: M L O'Toole; Karen C Johnson; Suzanne Satterfield; Andrew J Bush; Winston W K Koo; R C Klesges; William B Applegate
Do sweat calcium losses affect bone mass during firefighter training?
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2000;42(11):1054-9.
2000: William B Applegate; M Graney
Editor's note.
Journal of the American Geriatrics Society 2000;48(11):1539.
2000: Rekha Garg; Marshall B Elam; John R Crouse; KB Davis; JW Kennedy; DA Egan; J Alan Herd; Donald B Hunninghake; W C Johnson; John B Kostis; David S Sheps; William B Applegate
Effective and safe modification of multiple atherosclerotic risk factors in patients with peripheral arterial disease.
American heart journal 2000;140(5):792-803.
2000: Judith Hsia; James A Simon; F Lin; William B Applegate; M T Vogt; Donald B Hunninghake; M Carr
Peripheral arterial disease in randomized trial of estrogen with progestin in women with coronary heart disease: the Heart and Estrogen/Progestin Replacement Study.
Circulation 2000;102(18):2228-32.
2000: C M Chesney; Marshall B Elam; J Alan Herd; KB Davis; Rekha Garg; Donald B Hunninghake; JW Kennedy; William B Applegate
Effect of niacin, warfarin, and antioxidant therapy on coagulation parameters in patients with peripheral arterial disease in the Arterial Disease Multiple Intervention Trial (ADMIT).
American heart journal 2000;140(4):631-6.
2000: Lonneke V van de Poll-Franse; Marco Pahor; Mauro Di Bari; Ronald I Shorr; Jim Y Wan; Grant W Somes; William B Applegate
Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP).
Journal of hypertension 2000;18(8):1149-54.
2000: H M Perry; Barry R Davis; Thomas R Price; William B Applegate; W S Fields; J M Guralnik; L Kuller; Sara Pressel; J Stamler; Jeffrey L Probstfield
Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke: the Systolic Hypertension in the Elderly Program (SHEP).
JAMA : the journal of the American Medical Association 2000;284(4):465-71.
2000: Marco Pahor; Bruce M Psaty; Michael H Alderman; William B Applegate; Jeff D Williamson; Curt D Furberg
Therapeutic benefits of ACE inhibitors and other antihypertensive drugs in patients with type 2 diabetes.
Diabetes care 2000;23(7):888-92.
2000: D Chao; Mark A Espeland; Deborah Farmer; Thomas C Register; Leon Lenchik; William B Applegate; Walter H Ettinger
Effect of voluntary weight loss on bone mineral density in older overweight women.
Journal of the American Geriatrics Society 2000;48(7):753-9.
2000: Lonneke V van de Poll-Franse; Marco Pahor; Mauro Di Bari; Grant W Somes; William Cushman; William B Applegate
Hypokalemia associated with diuretic use and cardiovascular events in the Systolic Hypertension in the Elderly Program.
Hypertension 2000;35(5):1025-30.
1999: Karen C Johnson; Marshall J Graney; William B Applegate; Abbas E Kitabchi; John W Runyan; GH Rutan
Does syndrome X exist in hypertensive elderly persons with impaired glycemic control?
The journals of gerontology. Series A, Biological sciences and medical sciences 1999;54(11):M571-6.
1999: Grant W Somes; Marco Pahor; Ronald I Shorr; William Cushman; William B Applegate
The role of diastolic blood pressure when treating isolated systolic hypertension.
Archives of internal medicine 1999;159(17):2004-9.
1999: Robert P Byington; Gregory Evans; Mark A Espeland; William B Applegate; Donald B Hunninghake; Jeffrey L Probstfield; Curt D Furberg
Effects of lovastatin and warfarin on early carotid atherosclerosis: sex-specific analyses. Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group.
Circulation 1999;100(3):e14-7.
1999: Mark A Espeland; Paul K Whelton; John B Kostis; Judy Bahnson; Walter H Ettinger; Jeffrey A Cutler; Lawrence J Appel; Shiriki K Kumanyika; Deborah Farmer; JT Elam; Alan C Wilson; William B Applegate
Predictors and mediators of successful long-term withdrawal from antihypertensive medications. TONE Cooperative Research Group. Trial of Nonpharmacologic Interventions in the Elderly.
Archives of family medicine 1999;8(3):228-36.
1999: DA Egan; Rekha Garg; T J Wilt; Mary Pettinger; KB Davis; John R Crouse; J Alan Herd; Donald B Hunninghake; David S Sheps; John B Kostis; Jeffrey L Probstfield; Myron A Waclawiw; William B Applegate; Marshall B Elam
Rationale and design of the Arterial Disease Multiple Intervention Trial (ADMIT) pilot study.
The American journal of cardiology 1999;83(4):569-75.
1999: Marco Pahor; Marshall B Elam; R J Garrison; Stephen B Kritchevsky; William B Applegate
Emerging noninvasive biochemical measures to predict cardiovascular risk.
Archives of internal medicine 1999;159(3):237-45.
1999: Marco Pahor; Grant W Somes; Lonneke V van de Poll-Franse; R I Shorr; William B Applegate
Prevention of dementia: Syst-Eur trial.
Lancet 1999;353(9148):235; author reply 236-7.
1998: Steven R Cummings; Dennis M Black; Desmond E Thompson; William B Applegate; Elizabeth Barrett-Connor; TA Musliner; Lisa Palermo; R Prineas; Susan M Rubin; J C Scott; Thomas M. Vogt; Robert Wallace; AJ Yates; Andrea Z LaCroix
Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial.
JAMA : the journal of the American Medical Association 1998;280(24):2077-82.
1998: Deborah Grady; William B Applegate; Trudy L Bush; Curt D Furberg; B Riggs; Stephen B Hulley
Heart and Estrogen/progestin Replacement Study (HERS): design, methods, and baseline characteristics.
Controlled clinical trials 1998;19(4):314-35.
1998: Steven N Blair; William B Applegate; Andrea L Dunn; Walter H Ettinger; W L Haskell; Abby C King; Timothy M Morgan; J A Shih; Denise Simons-Morton
Activity Counseling Trial (ACT): rationale, design, and methods. Activity Counseling Trial Research Group.
Medicine and science in sports and exercise 1998;30(7):1097-106.
1998: Marco Pahor; Ronald I Shorr; Grant W Somes; William Cushman; Luigi Ferrucci; James E Bailey; JT Elam; William B Applegate
Diuretic-based treatment and cardiovascular events in patients with mild renal dysfunction enrolled in the systolic hypertension in the elderly program.
Archives of internal medicine 1998;158(12):1340-5.
1998: P J Savage; Sara Pressel; J D Curb; Eleanor Schron; William B Applegate; Henry R Black; J Cohen; Barry R Davis; P Frost; W Smith; N Gonzalez; G P Guthrie; A Oberman; GH Rutan; Jeffrey L Probstfield; J Stamler
Influence of long-term, low-dose, diuretic-based, antihypertensive therapy on glucose, lipid, uric acid, and potassium levels in older men and women with isolated systolic hypertension: The Systolic Hypertension in the Elderly Program. SHEP Cooperative Research Group.
Archives of internal medicine 1998;158(7):741-51.
1998: Cyril F Chang; Laurel J Kiser; J E Bailey; M Martins; W C Gibson; K A Schaberg; D M Mirvis; William B Applegate
Tennessee's failed managed care program for mental health and substance abuse services.
JAMA : the journal of the American Medical Association 1998;279(11):864-9.
1998: Paul K Whelton; Lawrence J Appel; Mark A Espeland; William B Applegate; Walter H Ettinger; John B Kostis; Shiriki K Kumanyika; Clifton R Lacy; Karen C Johnson; Steven Folmar; Jeffrey A Cutler
Sodium reduction and weight loss in the treatment of hypertension in older persons: a randomized controlled trial of nonpharmacologic interventions in the elderly (TONE). TONE Collaborative Research Group.
JAMA : the journal of the American Medical Association 1998;279(11):839-46.
1998: William B Applegate
Anti-hypertensive therapy reduced the incidence of stroke in older patients with isolated systolic hypertension.
Evidence-based cardiovascular medicine 1998;2(1):22.
1998: William B Applegate
Quality of life during antihypertensive treatment. Lessons from the Systolic Hypertension in the Elderly Program.
American journal of hypertension 1998;11(3 Pt 2):57S-61S.
1998: Ronald I Shorr; Karen C Johnson; Jim Y Wan; K Sutton-Tyrrell; M Pahor; J E Bailey; William B Applegate
The prognostic significance of asymptomatic carotid bruits in the elderly.
Journal of general internal medicine 1998;13(2):86-90.
1997: Marshall J Graney; William B Applegate
Sources of end-of-life ethics publications.
Archives of internal medicine 1997;157(22):2664.
1997: M Pahor; William B Applegate
Recent advances. Geriatric medicine.
BMJ (Clinical research ed.) 1997;315(7115):1071-4.
1997: John B Kostis; Barry R Davis; J Cutler; Richard H Grimm; K G Berge; J D Cohen; Clifton R Lacy; H M Perry; M Donald Blaufox; Sylvia Wassertheil-Smoller; Henry R Black; Eleanor Schron; D M Berkson; J D Curb; W M Smith; R McDonald; William B Applegate
Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension. SHEP Cooperative Research Group.
JAMA : the journal of the American Medical Association 1997;278(3):212-6.
1997: S S Solomon; William B Applegate
How the university medical center survived by going "back to the future".
The American journal of the medical sciences 1997;314(1):1-2.
1997: William B Applegate; M Pahor
Geriatric medicine.
JAMA : the journal of the American Medical Association 1997;277(23):1863-4.
1997: Karen C Johnson; Marshall J Graney; William B Applegate; Abbas E Kitabchi; John W Runyan; Ronald I Shorr
Prevalence of undiagnosed non-insulin-dependent diabetes mellitus and impaired glucose tolerance in a cohort of older persons with hypertension.
Journal of the American Geriatrics Society 1997;45(6):695-700.
1997: J Stamler; William B Applegate; J D Cohen; Jeffrey A Cutler; Paul K Whelton
More on dietary sodium and blood pressure.
JAMA : the journal of the American Medical Association 1997;277(20):1594-6.
1997: William B Applegate; M W Rich; M D Cheitlin
Integrating geriatrics into cardiology training programs.
Journal of the American Geriatrics Society 1997;45(5):641-2.
1997: Marshall B Elam; William Cushman; William B Applegate; M Heimberg
Recent developments in coronary heart disease prevention: the Scandinavian and west of Scotland studies.
Tennessee medicine : journal of the Tennessee Medical Association 1997;90(5):189-92.
1997: William B Applegate; Marshall J Graney
Overlapping publications.
Journal of the American Geriatrics Society 1997;45(2):249.
1997: William B Applegate; Curt D Furberg; Robert P Byington; R Grimm
The Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS)
JAMA : the journal of the American Medical Association 1997;277(4):297; author reply 297-8.
1997: William B Applegate; J D Cohen; P Wolfson; A Davis; S Green
Long-term effectiveness of enalapril plus extended-release diltiazem in essential hypertension.
Pharmacotherapy 1997;17(1):107-12.
1997: William B Applegate
Evolution of our understanding of the importance of elevated systolic blood pressure.
Tennessee medicine : journal of the Tennessee Medical Association 1997;90(1):24-6.
1997: Nancy C Santanello; BL Barber; William B Applegate; JT Elam; C Curtis; Donald B Hunninghake; D J Gordon
Effect of pharmacologic lipid lowering on health-related quality of life in older persons: results from the Cholesterol Reduction in Seniors Program (CRISP) Pilot Study.
Journal of the American Geriatrics Society 1997;45(1):8-14.
1997: Walter H Ettinger; R Burns; Stephen P Messier; William B Applegate; W Jack Rejeski; Timothy Morgan; Sally A Shumaker; Michael J Berry; M O'Toole; J Monu; Timothy E Craven
A randomized trial comparing aerobic exercise and resistance exercise with a health education program in older adults with knee osteoarthritis. The Fitness Arthritis and Seniors Trial (FAST).
JAMA : the journal of the American Medical Association 1997;277(1):25-31.
1996: J David Curb; S L Pressel; J A Cutler; P J Savage; William B Applegate; H Black; G Camel; Barry R Davis; P H Frost; N Gonzalez; G Guthrie; A Oberman; G H Rutan; J Stamler
Effect of diuretic-based antihypertensive treatment on cardiovascular disease risk in older diabetic patients with isolated systolic hypertension. Systolic Hypertension in the Elderly Program Cooperative Research Group.
JAMA : the journal of the American Medical Association 1996;276(23):1886-92.
1996: William B Applegate
Rationale and safety of angiotensin converting enzyme inhibitor combination with calcium channel blockers.
American journal of hypertension 1996;9(12 Pt 2):192S.
1996: P K Whelton; J D Cohen; William B Applegate
Dietary sodium and blood pressure.
JAMA : the journal of the American Medical Association 1996;276(18):1467-8; author reply 1469-70.
1996: Mark A Espeland; S Kumanyika; John B Kostis; J Algire; William B Applegate; Walter H Ettinger; Paul K Whelton; Judy Bahnson
Antihypertensive medication use among recruits for the Trial of Nonpharmacologic Interventions in the Elderly (TONE).
Journal of the American Geriatrics Society 1996;44(10):1183-9.
1996: Matthew R Weir; John M Flack; William B Applegate
Tolerability, safety, and quality of life and hypertensive therapy: the case for low-dose diuretics.
The American journal of medicine 1996;101(3A):83S-92S.
1996: William B Applegate; James R Sowers
Elevated systolic blood pressure: increased cardiovascular risk and rationale for treatment.
The American journal of medicine 1996;101(3A):3S-9S.
1996: Robert C Klesges; Kenneth D Ward; M L Shelton; William B Applegate; E D Cantler; G M Palmieri; K Harmon; J Davis
Changes in bone mineral content in male athletes. Mechanisms of action and intervention effects.
JAMA : the journal of the American Medical Association 1996;276(3):226-30.
1996: R J Garrison; L M Klesges; William B Applegate
Improving dietary patterns and physical activity levels among children and adolescents.
JAMA : the journal of the American Medical Association 1996;276(3):195.
1996: Michael J Berry; Peter H Brubaker; M L O'Toole; W Jack Rejeski; J Soberman; P M Ribisl; Henry S Miller; R F Afable; William B Applegate; Walter H Ettinger
Estimation of VO2 in older individuals with osteoarthritis of the knee and cardiovascular disease.
Medicine and science in sports and exercise 1996;28(7):808-14.
1996: William B Applegate; J D Cohen; P Wolfson; A Davis; S Green
Evaluation of blood pressure response to the combination of enalapril (single dose) and diltiazem ER (four different doses) in systemic hypertension.
The American journal of cardiology 1996;78(1):51-5.
1996: William B Applegate; R Burns
Geriatric medicine.
JAMA : the journal of the American Medical Association 1996;275(23):1812-3.
1996: Sylvia Wassertheil-Smoller; William B Applegate; K Berge; C J Chang; Barry R Davis; R Grimm; John B Kostis; S Pressel; Eleanor Schron
Change in depression as a precursor of cardiovascular events. SHEP Cooperative Research Group (Systoloc Hypertension in the elderly).
Archives of internal medicine 1996;156(5):553-61.
1995: Mark A Espeland; William B Applegate; Curt D Furberg; D Lefkowitz; L Rice; Donald B Hunninghake
Estrogen replacement therapy and progression of intimal-medial thickness in the carotid arteries of postmenopausal women. ACAPS Investigators. Asymptomatic Carotid Atherosclerosis Progression Study.
American journal of epidemiology 1995;142(10):1011-9.
1995: David M Mirvis; C F Chang; C J Hall; G T Zaar; William B Applegate
TennCare--health system reform for Tennessee.
JAMA : the journal of the American Medical Association 1995;274(15):1235-41.
1995: T A Hughes; Marshall B Elam; William B Applegate; M G Bond; S M Hughes; X Wang; Elizabeth A Tolley; J B Bittle; F B Stentz; ES Kang
Postprandial lipoprotein responses in hypertriglyceridemic subjects with and without cardiovascular disease.
Metabolism: clinical and experimental 1995;44(8):1082-98.
1995: Teri A Manolio; J A Cutler; Curt D Furberg; Bruce M Psaty; P K Whelton; William B Applegate
Trends in pharmacologic management of hypertension in the United States.
Archives of internal medicine 1995;155(8):829-37.
1995: J Probstfield; William B Applegate
Prospective meta-analysis: ahoy! A clinical trial?
Journal of the American Geriatrics Society 1995;43(4):452-3.
1995: M E Yamamoto; William B Applegate; Michael J Klag; N O Borhani; J D Cohen; K A Kirchner; E Lakatos; F M Sacks; J O Taylor; C H Hennekens
Lack of blood pressure effect with calcium and magnesium supplementation in adults with high-normal blood pressure. Results from Phase I of the Trials of Hypertension Prevention (TOHP). Trials of Hypertension Prevention (TOHP) Collaborative Research Group.
Annals of epidemiology 1995;5(2):96-107.
1995: Lawrence J Appel; M Espeland; Paul K Whelton; Therese A Dolecek; Shiriki K Kumanyika; William B Applegate; Walter H Ettinger; John B Kostis; Alan C Wilson; Clifton R Lacy
Trial of Nonpharmacologic Intervention in the Elderly (TONE). Design and rationale of a blood pressure control trial.
Annals of epidemiology 1995;5(2):119-29.
1995: JA Johnson; W S Akers; S T Miller; William B Applegate
Metoprolol minimizes nighttime blood pressure dip in hypertensive black males.
American journal of hypertension 1995;8(3):254-9.
1995: JA Johnson; W S Akers; S T Miller; William B Applegate
Lymphocyte beta 2-receptor activity, metoprolol kinetics, and response to metoprolol in hypertensive black men.
Pharmacotherapy 1995;15(2):150-7.
1995: Clarence E Davis; William B Applegate; D J Gordon; R C Curtis; M McCormick
An empirical evaluation of the placebo run-in.
Controlled clinical trials 1995;16(1):41-50.
1994: William B Applegate; S Pressel; Janet Wittes; J Luhr; R B Shekelle; G H Camel; M R Greenlick; E Hadley; L Moye; H M Perry
Impact of the treatment of isolated systolic hypertension on behavioral variables. Results from the systolic hypertension in the elderly program.
Archives of internal medicine 1994;154(19):2154-60.
1994: Curt D Furberg; H P Adams; William B Applegate; Robert P Byington; Mark A Espeland; Tyler D Hartwell; Donald B Hunninghake; D S Lefkowitz; Jeffrey L Probstfield; Ward A Riley
Effect of lovastatin on early carotid atherosclerosis and cardiovascular events. Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group.
Circulation 1994;90(4):1679-87.
1994: C V Ram; R P Ames; William B Applegate; J F Burris; M E Davidov; W J Mroczek
Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension.
Clinical cardiology 1994;17(5):251-6.
1994: J C LaRosa; William B Applegate; J R Crouse; Donald B Hunninghake; R Grimm; R Knopp; J H Eckfeldt; C E Davis; D J Gordon
Cholesterol lowering in the elderly. Results of the Cholesterol Reduction in Seniors Program (CRISP) pilot study.
Archives of internal medicine 1994;154(5):529-39.
1994: F M Sacks; P Hebert; Lawrence J Appel; N O Borhani; William B Applegate; J D Cohen; J A Cutler; K A Kirchner; L H Kuller; K J Roth
Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the Trials of Hypertension Prevention.
Journal of hypertension 1994;12(2):209-13.
1994: S T Miller; William B Applegate; J T Elam; Marshall J Graney
Influence of diagnostic classification on outcomes and charges in geriatric assessment and rehabilitation.
Journal of the American Geriatrics Society 1994;42(1):11-5.
1994: Frank M Sacks; P Hebert; Lawrence J Appel; N O Borhani; William B Applegate; J D Cohen; J A Cutler; K A Kirchner; L H Kuller; K J Roth
The effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the Trials of Hypertension Prevention. Trials of Hypertension Prevention Collaborative Research Group.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1994;12(7):S23-31.
1993: William B Applegate
Geriatricians are generalist physicians.
Academic medicine : journal of the Association of American Medical Colleges 1993;68(10):780-1.
1993: P E Pool; William B Applegate; T Woehler; P Sandall; W J Cady
A randomized, controlled trial comparing diltiazem, hydrochlorothiazide, and their combination in the therapy of essential hypertension.
Pharmacotherapy 1993;13(5):487-93.
1993: William B Applegate
Ankle/arm blood pressure index. A useful test for clinical practice?
JAMA : the journal of the American Medical Association 1993;270(4):497-8.
1993: William B Applegate
Managing the older patient with hypertension.
American journal of hypertension 1993;6(7 Pt 2):277S-282S.
1993: R Burns; Linda Nichols; Marshall J Graney; William B Applegate
Mortality in a public and a private hospital compared: the severity of antecedent disorders in Medicare patients.
American journal of public health 1993;83(7):966-71.
1993: F A Lederle; William B Applegate; R H Grimm
Reserpine and the medical marketplace.
Archives of internal medicine 1993;153(6):705-6.
1993: R N Paton; Marshall J Graney; J T Elam; William B Applegate
Prediction of elder caregiver burden.
Journal of the Tennessee Medical Association 1993;86(2):53-6.
1992: William B Applegate; G H Rutan
Advances in management of hypertension in older persons.
Journal of the American Geriatrics Society 1992;40(11):1164-74.
1992: William B Applegate
The relative importance of focusing on elevations of systolic vs diastolic blood pressure. A definitive answer at last.
Archives of internal medicine 1992;152(10):1969-71.
1992: Ward A Riley; R W Barnes; William B Applegate; R Dempsey; Tyler D Hartwell; V G Davis; M G Bond; Curt D Furberg
Reproducibility of noninvasive ultrasonic measurement of carotid atherosclerosis. The Asymptomatic Carotid Artery Plaque Study.
Stroke; a journal of cerebral circulation 1992;23(8):1062-8.
1992: William B Applegate
The hypertensive patient. Not just a number.
Postgraduate medicine 1992;92(1):237-44.
1992: William B Applegate; S T Miller; J T Elam; William Cushman; D el Derwi; A Brewer; Marshall J Graney
Nonpharmacologic intervention to reduce blood pressure in older patients with mild hypertension.
Archives of internal medicine 1992;152(6):1162-6.
1992: Paul K Whelton; P R Hebert; J Cutler; William B Applegate; K A Eberlein; Michael J Klag; M E Keough; S Hamill; N O Borhani; J Hollis
Baseline characteristics of participants in phase I of the Trials of Hypertension Prevention.
Annals of epidemiology 1992;2(3):295-310.
1992: William B Applegate
High blood pressure treatment in the elderly.
Clinics in geriatric medicine 1992;8(1):103-17.
1992: S T Miller; J T Elam; Marshall J Graney; William B Applegate
Discrepancies in recording systolic blood pressure of elderly persons by ambulatory blood pressure monitor.
American journal of hypertension 1992;5(1):16-21.
1992: William B Applegate
Systolic hypertension in older persons.
Advances in internal medicine 1992;37():37-54.
1991: William B Applegate; B R Davis; H R Black; W M Smith; S T Miller; A J Burlando
Prevalence of postural hypotension at baseline in the Systolic Hypertension in the Elderly Program (SHEP) cohort.
Journal of the American Geriatrics Society 1991;39(11):1057-64.
1991: William B Applegate; Marshall J Graney; S T Miller; J T Elam
Impact of a geriatric assessment unit on subsequent health care charges.
American journal of public health 1991;81(10):1302-6.
1991: J T Elam; Marshall J Graney; T Beaver; D el Derwi; William B Applegate; S T Miller
Comparison of subjective ratings of function with observed functional ability of frail older persons.
American journal of public health 1991;81(9):1127-30.
1991: William B Applegate; H L Phillips; H Schnaper; Alexander Shepherd; D Schocken; J C Luhr; Gary G Koch; G D Park
A randomized controlled trial of the effects of three antihypertensive agents on blood pressure control and quality of life in older women.
Archives of internal medicine 1991;151(9):1817-23.
1991: A Kramer; R Deyo; William B Applegate; S Meehan
Research strategies for geriatric evaluation and management: conference summary and recommendations.
Journal of the American Geriatrics Society 1991;39(9 Pt 2):53S-57S.
1991: D W Jahnigen; William B Applegate; H J Cohen; A Epstein; C Granger; D Hogan; R Kennedy; A Lazaroff
Working group recommendations: research on content and efficacy of geriatric evaluation and management interventions.
Journal of the American Geriatrics Society 1991;39(9 Pt 2):42S-44S.
1991: William B Applegate; R Deyo; A Kramer; S Meehan
Geriatric evaluation and management: current status and future research directions.
Journal of the American Geriatrics Society 1991;39(9 Pt 2):2S-7S.
1991: Laurence Z Rubenstein; William B Applegate; John R Burton; K Hyer; L G Pawlson; C H Winograd
Medicare reimbursement for geriatric assessment: report of the American Geriatrics Society Ad Hoc Committee on Geriatrics Assessment.
Journal of the American Geriatrics Society 1991;39(9):926-31.
1991: S Satterfield; J A Cutler; H G Langford; William B Applegate; N O Borhani; E Brittain; J D Cohen; L H Kuller; Norman L Lasser; A Oberman
Trials of hypertension prevention. Phase I design.
Annals of epidemiology 1991;1(5):455-71.
1991: J D Curb; M Lee; J Jensen; William B Applegate
Systolic Hypertension in the Elderly Program (SHEP). Part 4: Baseline medical history findings.
Hypertension 1991;17(3 Suppl):II35-61.
1991: N O Borhani; William B Applegate; J A Cutler; Barry R Davis; Curt D Furberg; E Lakatos; L Page; H M Perry; W M Smith; J L Probstfield
Systolic Hypertension in the Elderly Program (SHEP). Part 1: Rationale and design.
Hypertension 1991;17(3 Suppl):II2-15.
1991: William B Applegate; N Borhani; V DeQuattro; P M Kaihlanen; S Oishi; D L Due; M A Sirgo
Comparison of labetalol versus enalapril as monotherapy in elderly patients with hypertension: results of 24-hour ambulatory blood pressure monitoring.
The American journal of medicine 1991;90(2):198-205.
1991: William B Applegate; R P Byington
MIDAS, the Multicenter Isradipine/Diuretic Atherosclerosis Study. Design features and baseline data.
American journal of hypertension 1991;4(2 Pt 2):114S-117S.
1991: William B Applegate; J P Hughes; R Vander Zwaag
Case-control study of coronary heart disease risk factors in the elderly.
Journal of clinical epidemiology 1991;44(4-5):409-15.
1990: William B Applegate; J D Curb
Designing and executing randomized clinical trials involving elderly persons.
Journal of the American Geriatrics Society 1990;38(8):943-50.
1990: William B Applegate; S T Miller; Marshall J Graney; J T Elam; R Burns; D E Akins
A randomized, controlled trial of a geriatric assessment unit in a community rehabilitation hospital.
The New England journal of medicine 1990;322(22):1572-8.
1990: P C Rosmarin; William B Applegate; G W Somes
Coffee consumption and blood pressure: a randomized, crossover clinical trial.
Journal of general internal medicine 1990;5(3):211-3.
1990: William B Applegate; J P Blass; T F Williams
Instruments for the functional assessment of older patients.
The New England journal of medicine 1990;322(17):1207-14.
1990: P C Rosmarin; William B Applegate; G W Somes
Coffee consumption and serum lipids: a randomized, crossover clinical trial.
The American journal of medicine 1990;88(4):349-56.
1990: William B Applegate; M E Williams
Career development in academic medicine.
The American journal of medicine 1990;88(3):263-7.
1990: Marshall J Graney; William B Applegate; S T Miller; J T Elam; T C Gettelfinger; T O Wood; J M Freeman
An index for estimating probabilities of surgical success for cataract patients with retinal disease.
Journal of gerontology 1990;45(2):M40-4.
1989: William B Applegate; S T Miller
Choice of antihypertensive medication regimen.
Clinics in geriatric medicine 1989;5(4):803-11.
1989: William B Applegate
Hypertension in elderly patients.
Annals of internal medicine 1989;110(11):901-15.
1989: William B Applegate
Therapeutic choices for the older hypertensive patient.
Journal of the National Medical Association 1989;81 Suppl():25-9.
1989: M A Sirgo; B K Boyd; William B Applegate
Treatment of hypertension in the elderly with labetalol.
Pharmacotherapy 1989;9(5):295-302.
1989: Jeffrey L Probstfield; William B Applegate; N O Borhani; J David Curb; J A Cutler; Barry R Davis; Curt D Furberg; C M Hawkins; E Lakatos; L B Page
The Systolic Hypertension in the Elderly Program (SHEP): an intervention trial on isolated systolic hypertension. SHEP Cooperative Research Group.
Clinical and experimental hypertension. Part A, Theory and practice 1989;11(5-6):973-89.
1988: J T Elam; Marshall J Graney; William B Applegate; S T Miller; J M Freeman; T O Wood; T C Gettlefinger
Functional outcome one year following cataract surgery in elderly persons.
Journal of gerontology 1988;43(5):M122-6.
1988: S T Miller; Marshall J Graney; J T Elam; William B Applegate; J M Freeman
Predictions of outcomes from cataract surgery in elderly persons.
Ophthalmology 1988;95(8):1125-9.
1988: Marshall J Graney; William B Applegate; S T Miller; J T Elam; J M Freeman; T O Wood; T C Gettlefinger
A clinical index for predicting visual acuity after cataract surgery.
American journal of ophthalmology 1988;105(5):460-5.
1988: J F Burris; R P Ames; William B Applegate; C V Ram; M E Davidov; W J Mroczek
Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension.
Journal of cardiovascular pharmacology 1988;12 Suppl 7():S98-102.
1987: William B Applegate; S T Miller; J T Elam; J M Freeman; T O Wood; T C Gettlefinger
Impact of cataract surgery with lens implantation on vision and physical function in elderly patients.
JAMA : the journal of the American Medical Association 1987;257(8):1064-6.
1987: William B Applegate; D E Akins; J T Elam
A geriatric assessment and rehabilitation unit in a rehabilitation hospital.
Clinics in geriatric medicine 1987;3(1):145-54.
1987: William B Applegate
Use of assessment instruments in clinical settings.
Journal of the American Geriatrics Society 1987;35(1):45-50.
1986: William B Applegate
Physician management of patients with adverse outcomes.
Archives of internal medicine 1986;146(11):2249-52.
1985: C B Perry; William B Applegate
Medical paternalism and patient self-determination.
Journal of the American Geriatrics Society 1985;33(5):353-9.
1985: S T Miller; William B Applegate; C Perry
Clinical trials in elderly persons.
Journal of the American Geriatrics Society 1985;33(2):91-2.
1985: William B Applegate; E R Carper; S E Kahn; L Westbrook; M Linton; M G Baker; J W Runyan
Comparison of the use of reserpine versus alpha-methyldopa for second step treatment of hypertension in the elderly.
Journal of the American Geriatrics Society 1985;33(2):109-15.
1984: William B Applegate; S Graves; T Collins; R Vander Zwaag; D Akins
Acute myocardial infarction in elderly patients.
Southern medical journal 1984;77(9):1127-9.
1984: R E White; B J Skipper; William B Applegate; M D Bennett; L A Chilton
Ordering decision and clinic cost variation among resident physicians.
The Western journal of medicine 1984;141(1):117-22.
1984: William B Applegate
The femoral cement compactor.
The Journal of bone and joint surgery. American volume 1984;66(5):808.
1984: William B Applegate; J Mann
Hypertension in the elderly.
Journal of the Tennessee Medical Association 1984;77(4):216.
1984: William B Applegate; D Akins
Approach to the elderly confused person. Part II--Evaluation of chronic dementia.
Journal of the Tennessee Medical Association 1984;77(3):153-4.
1984: William B Applegate; D Akins
Approach to the elderly confused person. Part I--Evaluation and consideration of delirium.
Journal of the Tennessee Medical Association 1984;77(2):90-1.
1984: William B Applegate; S E Dismuke; J W Runyan
Treatment of hypertension in the elderly: a time for caution?
Journal of the American Geriatrics Society 1984;32(1):21-3.
1983: B P Quinn; William B Applegate; K Roberts; T Collins; R Vanderzwaag
Knowledge and use of medications in a group of elderly individuals.
Journal of the Tennessee Medical Association 1983;76(10):647-9.
1983: M D Bennett; William B Applegate; L A Chilton; B J Skipper; R E White
Comparison of family medicine and internal medicine: charges for continuing ambulatory care.
Medical care 1983;21(8):830-9.
1983: William B Applegate; M D Bennett; L Chilton; B J Skipper; R E White
Impact of a cost-containment educational program on housestaff ambulatory clinic charges.
Medical care 1983;21(5):486-96.
1983: William B Applegate; D Akins; R Vander Zwaag; K Thoni; M G Baker
A geriatric rehabilitation and assessment unit in a community hospital.
Journal of the American Geriatrics Society 1983;31(4):206-10.
1982: L A Chilton; William B Applegate; M D Bennett; B E Skipper; R E White
Evaluation of educational methods in a comprehensive cost-containment project in ambulatory care.
Southern medical journal 1982;75(10):1251-5.
1982: William B Applegate; R Vander Zwaag; S E Dismuke; J W Runyan
Control of systolic blood pressure in elderly black patients.
Journal of the American Geriatrics Society 1982;30(6):391-6.
1981: William B Applegate; J W Runyan; L Brasfield; M L Williams; C Konigsberg; C Fouche
Analysis of the 1980 heat wave in Memphis.
Journal of the American Geriatrics Society 1981;29(8):337-42.
1981: William B Applegate
Decision theory for clinicians: uses and misuses of clinical tests.
Southern medical journal 1981;74(4):468-73.
1981: William B Applegate; M H Spector
Colorectal cancer screening.
Journal of community health 1981;7(2):138-51.
1981: M H Spector; William B Applegate; S J Olmstead; P V DiVasto; B Skipper
Assessment of attitudes toward mass screening for colorectal cancer and polyps.
Preventive medicine 1981;10(1):105-9.
1979: William B Applegate
Technology and values in medicine.
Forum on medicine 1979;2(11):748-50.
1979: M L Garg; M J Garland; William B Applegate; J M Eisenberg; J G Freymann; J I Hudson
Symposium: New horizons in cost containment curricula.
Annual Conference on Research in Medical Education. Conference on Research in Medical Education 1979;18():399-405.
1976: C B Lyle; William B Applegate; D S Citron; Dale O Williams
Practice habits in a group of eight internists.
Annals of internal medicine 1976;84(5):594-601.
1972: R C Levy; William B Applegate
Student-community health projects. How to win friends without influencing people.
JAMA : the journal of the American Medical Association 1972;220(8):1113-5.
1972: William B Applegate; R C Levy
The role of community health in the education of Health Science students.
The Journal of the Kentucky Medical Association 1972;70(3):214-5.