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Michael Gardner

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
23
Hostetler, Karl
9
Beadle, James
8
Aldern, Kathy
7
Bergeron-Lynn, Germaine
7
Cheng, Lingyun
7
Freeman, William
5
Richman, Douglas
4
Kini, GD
4
Wright, KN
3
Severson, GM
3
Keefe, KS
3
Chaidhawangul, Sunan
3
Avila, CP
2
Kern, Earl
2
Mueller, Arthur

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Publications

TOP 3
Cheng Lingyun; Hostetler Karl Y; Toyoguchi Mitsuko; Beadle James R; Rodanant Nuttawut; Gardner Michael F; Aldern Kathy A; Bergeron-Lynn Germaine; Freeman William R
Ganciclovir release rates in vitreous from different formulations of 1-O-hexadecylpropanediol-3-phospho-ganciclovir.
Cheng Lingyun; Hostetler Karl Y; Chaidhawangul Sunan; Gardner Michael F; Beadle James R; Toyoguchi Mitsuko; Bergeron-Lynn Germaine; Freeman William R
Treatment or prevention of herpes simplex virus retinitis with intravitreally injectable crystalline 1-O-hexadecylpropanediol-3-phospho-ganciclovir.
Hostetler K Y; Rybak R J; Beadle J R; Gardner M F; Aldern K A; Wright K N; Kern E R
In vitro and in vivo activity of 1-O-hexadecylpropanediol-3-phospho-ganciclovir and 1-O-hexadecylpropanediol-3-phospho-penciclovir in cytomegalovirus and herpes simplex virus infections.

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All Publications

2003: Cheng Lingyun; Hostetler Karl Y; Toyoguchi Mitsuko; Beadle James R; Rodanant Nuttawut; Gardner Michael F; Aldern Kathy A; Bergeron-Lynn Germaine; Freeman William R
Ganciclovir release rates in vitreous from different formulations of 1-O-hexadecylpropanediol-3-phospho-ganciclovir.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2003;19(2):161-9.
2002: Cheng Lingyun; Hostetler Karl Y; Chaidhawangul Sunan; Gardner Michael F; Beadle James R; Toyoguchi Mitsuko; Bergeron-Lynn Germaine; Freeman William R
Treatment or prevention of herpes simplex virus retinitis with intravitreally injectable crystalline 1-O-hexadecylpropanediol-3-phospho-ganciclovir.
Investigative ophthalmology & visual science 2002;43(2):515-21.
2001: Hostetler K Y; Rybak R J; Beadle J R; Gardner M F; Aldern K A; Wright K N; Kern E R
In vitro and in vivo activity of 1-O-hexadecylpropanediol-3-phospho-ganciclovir and 1-O-hexadecylpropanediol-3-phospho-penciclovir in cytomegalovirus and herpes simplex virus infections.
Antiviral chemistry & chemotherapy 2001;12(1):61-70.
2000: Cheng L; Hostetler K Y; Chaidhawangul S; Gardner M F; Beadle J R; Keefe K S; Bergeron-Lynn G; Severson G M; Soules K A; Mueller A J; Freeman W R
Intravitreal toxicology and duration of efficacy of a novel antiviral lipid prodrug of ganciclovir in liposome formulation.
Investigative ophthalmology & visual science 2000;41(6):1523-32.
2000: Beadle J R; Kini G D; Aldern K A; Gardner M F; Wright K N; Rybak R J; Kern E R; Hostetler K Y
Synthesis and antiviral evaluation of 1-O-hexadecylpropanediol-3-P-acyclovir: efficacy against HSV-1 infection in mice.
Nucleosides, nucleotides & nucleic acids 2000;19(1-2):471-9.
1999: Cheng L; Hostetler K Y; Gardner M F; Avila C P; Bergeron-Lynn G; Keefe K S; Beadle J R; Wiley C A; Freeman W R
Intravitreal toxicology and therapeutic efficacy of the carboxymethyl ester of the 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA-O-Me), a novel lipid antiviral prodrug for intraocular drug delivery.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 1999;15(4):363-77.
1999: Cheng L; Hostetler K Y; Gardner M F; Avila C P; Bergeron-Lynn G; Keefe K S; Wiley C A; Freeman W R
Intravitreal toxicology in rabbits of two preparations of 1-O-octadecyl-sn-glycerol-3-phosphonoformate, a sustained-delivery anti-CMV drug.
Investigative ophthalmology & visual science 1999;40(7):1487-95.
1999: Cheng L; Hostetler K Y; Gardner M F; Avila C P; Bergeron-Lynn G; Severson G M; Freeman W R
Intravitreal pharmacokinetics in rabbits of the foscarnet lipid prodrug: 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA).
Current eye research 1999;18(3):161-7.
1999: Cheng L; Hostetler K Y; Chaidhawangul S; Gardner M F; Ozerdem U; Bergeron-Lynn G; Mach-Hofacre B; Mueller A J; Severson G M; Freeman W R
Treatment of herpes retinitis in an animal model with a sustained delivery antiviral drug, liposomal 1-O-octadecyl-SN-glycerol-3-phosphonoformate.
Retina (Philadelphia, Pa.) 1999;19(4):325-31.
1998: Beadle J R; Kini G D; Aldern K A; Gardner M F; Wright K N; Richman D D; Hostetler K Y
Alkylthioglycerol prodrugs of foscarnet: synthesis, oral bioavailability and structure-activity studies in human cytomegalovirus-, herpes simplex virus type 1- and human immunodeficiency virus type 1-infected cells.
Antiviral chemistry & chemotherapy 1998;9(1):33-40.
1997: Hostetler K Y; Beadle J R; Kini G D; Gardner M F; Wright K N; Wu T H; Korba B A
Enhanced oral absorption and antiviral activity of 1-O-octadecyl-sn-glycero-3-phospho-acyclovir and related compounds in hepatitis B virus infection, in vitro.
Biochemical pharmacology 1997;53(12):1815-22.
1996: Hostetler K Y; Kini G D; Beadle J R; Aldern K A; Gardner M F; Border R; Kumar R; Barshak L; Sridhar C N; Wheeler C J; Richman D D
Lipid prodrugs of phosphonoacids: greatly enhanced antiviral activity of 1-O-octadecyl-sn-glycero-3-phosphonoformate in HIV-1, HSV-1 and HCMV-infected cells, in vitro.
Antiviral research 1996;31(1-2):59-67.
1996: Reasor M J; McCloud C M; Beard T L; Ebert D C; Kacew S; Gardner M F; Aldern K A; Hostetler K Y
Comparative evaluation of amiodarone-induced phospholipidosis and drug accumulation in Fischer-344 and Sprague-Dawley rats.
Toxicology 1996;106(1-3):139-47.
1994: Hostetler K Y; Richman D D; Sridhar C N; Felgner P L; Felgner J; Ricci J; Gardner M F; Selleseth D W; Ellis M N
Phosphatidylazidothymidine and phosphatidyl-ddC: assessment of uptake in mouse lymphoid tissues and antiviral activities in human immunodeficiency virus-infected cells and in Rauscher leukemia virus-infected mice.
Antimicrobial agents and chemotherapy 1994;38(12):2792-7.
1994: Hostetler K Y; Richman D D; Forssen E A; Selk L; Basava R; Gardner M F; Parker S; Basava C
Phospholipid prodrug inhibitors of the HIV protease. Antiviral activity and pharmacokinetics in rats.
Biochemical pharmacology 1994;48(7):1399-404.
1994: Hostetler K Y; Korba B E; Sridhar C N; Gardner M F
Antiviral activity of phosphatidyl-dideoxycytidine in hepatitis B-infected cells and enhanced hepatic uptake in mice.
Antiviral research 1994;24(1):59-67.
1993: Hostetler K Y; Parker S; Sridhar C N; Martin M J; Li J L; Stuhmiller L M; van Wijk G M; van den Bosch H; Gardner M F; Aldern K A
Acyclovir diphosphate dimyristoylglycerol: a phospholipid prodrug with activity against acyclovir-resistant herpes simplex virus.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11835-9.
1993: Huterer S J; Hostetler K Y; Gardner M F; Wherrett J R
Lysosomal phosphatidylcholine: bis(monoacylglycero)phosphate acyltransferase: specificity for the sn-1 fatty acid of the donor and co-purification with phospholipase A1.
Biochimica et biophysica acta 1993;1167(2):204-10.
1992: Kumar R; Gardner M F; Richman D D; Hostetler K Y
Equal inhibition of HIV replication by stereoisomers of phosphatidyl-azidothymidine. Lack of stereospecificity of lysosomal phospholipase A1.
The Journal of biological chemistry 1992;267(28):20288-92.
1991: Hostetler K Y; Gardner M F
Purification of rat kidney lysosomal phospholipase A1.
Methods in enzymology 1991;197():325-30.
1991: Hostetler K Y; Gardner M F; Aldern K A
Assay of phospholipases C and D in presence of other lipid hydrolases.
Methods in enzymology 1991;197():125-34.
1986: Kubo M; Gardner M F; Hostetler K Y
Binding of propranolol and gentamicin to small unilamellar phospholipid vesicles. Contribution of ionic and hydrophobic forces.
Biochemical pharmacology 1986;35(21):3761-5.
1986: Hostetler K Y; Gardner M F; Giordano J R
Purification of lysosomal phospholipase A and demonstration of proteins that inhibit phospholipase A in a lysosomal fraction from rat kidney cortex.
Biochemistry 1986;25(21):6456-61.

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