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Cecilia Garlanda

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Roberto Ronca; Regina Tardanico; Chiara Tobia; william vermi; Patrizia Alessi; Mirella Belleri; Elisa Bonomi; Daniela Coltrini; Michela Corsini; Emanuela Di Salle; Cecilia Garlanda; Arianna Giacomini; Daria Leali; Marco Presta
Long pentraxin-3 as an epithelial-stromal fibroblast growth factor-targeting inhibitor in prostate cancer.
Maciej Lech; Alberto Mantovani; Christoph Reichel; Christoph Römmele; Bernd Uhl; Shijun Wang; Heni Eka Susanti; Cecilia Garlanda; Regina Gröbmayr; Hermann-Josef Gröne; Fritz Krombach; Onkar P Kulkarni; Hans-Joachim Anders
Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury.
Valeria Cozzi; Cecilia Garlanda; virginia maina; A Martinelli; Manuela Nebuloni; S Calabrese; Irene Cetin
PTX3 as a potential endothelial dysfunction biomarker for severity of preeclampsia and IUGR.

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All Publications

2013: Roberto Ronca; Regina Tardanico; Chiara Tobia; william vermi; Patrizia Alessi; Mirella Belleri; Elisa Bonomi; Daniela Coltrini; Michela Corsini; Emanuela Di Salle; Cecilia Garlanda; Arianna Giacomini; Daria Leali; Marco Presta
Long pentraxin-3 as an epithelial-stromal fibroblast growth factor-targeting inhibitor in prostate cancer.
The Journal of pathology 2013;230(2):228-38.
2013: Maciej Lech; Alberto Mantovani; Christoph Reichel; Christoph Römmele; Bernd Uhl; Shijun Wang; Heni Eka Susanti; Cecilia Garlanda; Regina Gröbmayr; Hermann-Josef Gröne; Fritz Krombach; Onkar P Kulkarni; Hans-Joachim Anders
Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury.
Kidney international 2013;83(4):647-61.
2012: Valeria Cozzi; Cecilia Garlanda; virginia maina; A Martinelli; Manuela Nebuloni; S Calabrese; Irene Cetin
PTX3 as a potential endothelial dysfunction biomarker for severity of preeclampsia and IUGR.
Placenta 2012;33(12):1039-44.
2012: Andrea Doni; Cecilia Garlanda; Peter Garred; Barbara Bottazzi; Seppo Meri; Alberto Mantovani
Interactions of the humoral pattern recognition molecule PTX3 with the complement system.
Immunobiology 2012;217(11):1122-8.
2012: Daria Leali; Giuseppe D Norata; Roberto Ronca; Marina Sironi; Mirella Belleri; Roberta Bianchi; Barbara Bottazzi; Daniela Coltrini; Anthony J Day; Emanuela Di Salle; Cecilia Garlanda; Antonio Inforzato; Marco Presta
Long pentraxin 3/tumor necrosis factor-stimulated gene-6 interaction: a biological rheostat for fibroblast growth factor 2-mediated angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(3):696-703.
2012: Jacob S Lee; Alberto Mantovani; Keely G McDonald; Rodney D Newberry; Manabu Nukaya; Christopher A Bradfield; Marina Cella; Cecilia Garlanda; Gregory D Kennedy; Raphael Kopan; Marco COLONna
AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch.
Nature immunology 2012;13(2):144-51.
2012: Antonio Inforzato; Elisa Barbati; Barbara Bottazzi; Cecilia Garlanda; Patrick C Reading; Alberto Mantovani
The "sweet" side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation.
Frontiers in immunology 2012;3():407.
2012: Elisa Barbati; Simona Barlera; Barbara Bottazzi; Luisa Crociati; Carmela d'Arienzo; Raffaele Fanelli; Cecilia Garlanda; Francesca Gori; Ruggiero Mango; Alberto Mantovani; Giuseppe Merla; Enrico Nicolis; Silvia Pietri; Patrizia Presbitero; Marco Luciano Rossi; Claudia Specchia; Yukio Sudo; Massimo Villella; Alessandro Villella; Maria Grazia Franzosi
Influence of pentraxin 3 (PTX3) genetic variants on myocardial infarction risk and PTX3 plasma levels.
PloS one 2012;7(12):e53030.
2012: Federica Riva; Elisa Barbati; Eduardo Bonavita; Alberto Mantovani; Marta Muzio; Cecilia Garlanda
TIR8/SIGIRR is an Interleukin-1 Receptor/Toll Like Receptor Family Member with Regulatory Functions in Inflammation and Immunity.
Frontiers in immunology 2012;3():322.
2012: Antonio Inforzato; Barbara Bottazzi; Cecilia Garlanda; Sonia Valentino; Alberto Mantovani
Pentraxins in humoral innate immunity.
Advances in experimental medicine and biology 2012;946():1-20.
2012: Silvia Oldani; Serenella Valaperta; Marco Albini; Eleonora Baldassarre; Barbara Bottazzi; Maurice Child; Ivan Cuccovillo; Silvia Finazzi; Cecilia Garlanda; Giorgio Graziani; Alessandro Montanelli; Salvatore Badalamenti
Plasma pentraxin-3 as a marker of bioincompatibility in hemodialysis patients.
Journal of nephrology 2012;25(1):120-6.
2011: Maria T S Bertilaccio; Federico Caligaris-Cappio; Antonis Dagklis; Cecilia Garlanda; Paolo Ghia; Alberto Mantovani; Maurilio Ponzoni; Martina Rocchi; Tania Veliz Rodriguez; Giorgia Simonetti; Benedetta Apollonio; Marta Muzio
Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models.
Blood 2011;118(3):660-9.
2011: Norma Maugeri; Patrizia Rovere-Querini; Massimo Slavich; Alberto Mantovani; Attilio Maseri; Barbara Bottazzi; Domenico Cianflone; Giovanni Coppi; Andrea Doni; Cecilia Garlanda; Angelo A Manfredi
Early and transient release of leukocyte pentraxin 3 during acute myocardial infarction.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(2):970-9.
2011: FEDERICA MOALLI; Moira Paroni; Tania Véliz Rodriguez; Federica Riva; Nadia Polentarutti; Barbara Bottazzi; Sonia Valentino; Stefano Mantero; Manuela Nebuloni; Alberto Mantovani; Alessandra Bragonzi; Cecilia Garlanda
The therapeutic potential of the humoral pattern recognition molecule PTX3 in chronic lung infection caused by Pseudomonas aeruginosa.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(9):5425-34.
2011: Derek A Costello; Melanie B Watson; Thelma R Cowley; Niamh Murphy; Ciarán Murphy Royal; Cecilia Garlanda; Marina A Lynch
Interleukin-1alpha and HMGB1 mediate hippocampal dysfunction in SIGIRR-deficient mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(10):3871-9.
2011: Elisa Roncati Zanier; Giovanna Brandi; Giuseppe Peri; Luca Longhi; Tommaso Zoerle; Mauro Tettamanti; Cecilia Garlanda; Anna Sigurtà; Serenella Valaperta; Alberto Mantovani; Maria Grazia De Simoni; Nino Stocchetti
Cerebrospinal fluid pentraxin 3 early after subarachnoid hemorrhage is associated with vasospasm.
Intensive care medicine 2011;37(2):302-9.
2011: FEDERICA MOALLI; Marina Sironi; Barbara Bottazzi; Antonio Inforzato; Sebastien Jaillon; Alberto Mantovani; Cecilia Garlanda
Pathogen recognition by the long pentraxin PTX3.
Journal of biomedicine & biotechnology 2011;2011():830421.
2011: Maciej Lech; Christoph Römmele; Onkar P Kulkarni; Heni Eka Susanti; Adriana Migliorini; Cecilia Garlanda; Alberto Mantovani; Hans-Joachim Anders
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus.
PloS one 2011;6(5):e20118.
2011: Veronika Skuginna; Maciej Lech; Ramanjaneyulu Allam; Mi Ryu; Sebastian Clauss; Heni Eka Susanti; Christoph Römmele; Cecilia Garlanda; Alberto Mantovani; Hans-Joachim Anders
Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction.
PloS one 2011;6(4):e19204.
2011: Cecilia Garlanda; Barbara Bottazzi; FEDERICA MOALLI; Livija Deban; Fabiola Molla; Roberto Latini; Alberto Mantovani
Pentraxins and atherosclerosis: the role of PTX3.
Current pharmaceutical design 2011;17(1):38-46.
2011: Livija Deban; Sebastien Jaillon; Cecilia Garlanda; Barbara Bottazzi; Alberto Mantovani
Pentraxins in innate immunity: lessons from PTX3.
Cell and tissue research 2011;343(1):237-49.
2011: Manuela Nebuloni; Fabio Pasqualini; Pietro Zerbi; Eleonora Lauri; Alberto Mantovani; Luca Vago; Cecilia Garlanda
PTX3 expression in the heart tissues of patients with myocardial infarction and infectious myocarditis.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2011;20(1):e27-35.
2010: FEDERICA MOALLI; Andrea Doni; Livija Deban; Teresa Zelante; Silvia Zagarella; Barbara Bottazzi; Luigina Romani; Alberto Mantovani; Cecilia Garlanda
Role of complement and Fc{gamma} receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus.
Blood 2010;116(24):5170-80.
2010: Karel Otero; Annunciata Vecchi; Emilio Hirsch; Jennifer Kearley; william vermi; Annalisa Del Prete; Safiyè Gonzalvo-Feo; Cecilia Garlanda; Ornella Azzolino; Laura Salogni; Clare M Lloyd; Fabio Facchetti; Alberto Mantovani; Silvano Sozzani
Nonredundant role of CCRL2 in lung dendritic cell trafficking.
Blood 2010;116(16):2942-9.
2010: Chiara Agostinis; Roberta Bulla; Claudio Tripodo; Angela Gismondi; Helena Stabile; Fleur Bossi; Carla Guarnotta; Cecilia Garlanda; Francesco De Seta; Paola Spessotto; Angela Santoni; Berhane Ghebrehiwet; Guillermina Girardi; Francesco Tedesco
An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(7):4420-9.
2010: Stefan K Drexler; Philip Kong; Julia Inglis; Richard O Williams; Cecilia Garlanda; Alberto Mantovani; Amir S Yazdi; Fionula Brennan; Eugene Eyo Akujuru; Brian M J Foxwell
SIGIRR/TIR-8 is an inhibitor of Toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis.
Arthritis and rheumatism 2010;62(8):2249-61.
2010: Graziella Solinas; Federica Marchesi; Cecilia Garlanda; Alberto Mantovani; Paola Allavena
Inflammation-mediated promotion of invasion and metastasis.
Cancer metastasis reviews 2010;29(2):243-8.
2010: Alberto Mantovani; Cecilia Garlanda; Paola Allavena
Molecular pathways and targets in cancer-related inflammation.
Annals of medicine 2010;42(3):161-70.
2010: Livija Deban; Remo Castro Russo; Marina Sironi; FEDERICA MOALLI; Margherita Scanziani; Vanessa Zambelli; Ivan Cuccovillo; Antonio Bastone; Marco Gobbi; Sonia Valentino; Andrea Doni; Cecilia Garlanda; Silvio Danese; Giovanni Salvatori; Marica Sassano; Virgilio Evangelista; Barbara Rossi; Elena Zenaro; Gabriela Constantin; Carlo Laudanna; Barbara Bottazzi; Alberto Mantovani
Regulation of leukocyte recruitment by the long pentraxin PTX3.
Nature immunology 2010;11(4):328-34.
2010: Maciej Lech; Veronika Skuginna; Onkar P Kulkarni; Jing Gong; Tiandi Wei; Robert W Stark; Cecilia Garlanda; Alberto Mantovani; Hans-Joachim Anders
Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis.
The Journal of pathology 2010;220(5):596-607.
2010: Giuseppe D Norata; Cecilia Garlanda; Alberico Luigi Catapano
The long pentraxin PTX3: a modulator of the immunoinflammatory response in atherosclerosis and cardiovascular diseases.
Trends in cardiovascular medicine 2010;20(2):35-40.
2010: Martijn D de Kruif; Maarten Limper; Karlien Sierhuis; Jiri F P Wagenaar; C Arnold Spek; Cecilia Garlanda; Alessia Cotena; Alberto Mantovani; Hugo ten Cate; Pieter H Reitsma; Eric C M van Gorp
PTX3 predicts severe disease in febrile patients at the emergency department.
The Journal of infection 2010;60(2):122-7.
2010: Rosaria Cammarota; Valentina Bertolini; Giuseppina Pennesi; Eraldo O Bucci; Ornella Gottardi; Cecilia Garlanda; Luigi Laghi; Massimo C Barberis; Fausto Sessa; Douglas M Noonan; Adriana Albini
The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker.
Journal of translational medicine 2010;8():112.
2010: Nele S Pauwels; Ken R Bracke; Tania Maes; Geert R Van Pottelberge; Cecilia Garlanda; Alberto Mantovani; Guy FP JOOS; Guy G Brusselle
Cigarette smoke induces PTX3 expression in pulmonary veins of mice in an IL-1 dependent manner.
Respiratory research 2010;11():134.
2010: Barbara Bottazzi; Andrea Doni; Cecilia Garlanda; Alberto Mantovani
An integrated view of humoral innate immunity: pentraxins as a paradigm.
Annual review of immunology 2010;28():157-83.
2009: Cecilia Garlanda; Virginia Maina; Alessia Cotena; FEDERICA MOALLI
The soluble pattern recognition receptor pentraxin-3 in innate immunity, inflammation and fertility.
Journal of reproductive immunology 2009;83(1-2):128-33.
2009: Marina Noris; Paola Cassis; Nadia Azzollini; Regiane Cavinato; Daniela Cugini; Federica Casiraghi; Sistiana Aiello; Samantha Solini; linda cassis; Marilena Mister; Marta Todeschini; Mauro Abbate; Ariela Benigni; Piera Trionfini; Susanna Tomasoni; Caterina Mele; Cecilia Garlanda; Nadia Polentarutti; Alberto Mantovani; Giuseppe Remuzzi
The Toll-IL-1R member Tir8/SIGIRR negatively regulates adaptive immunity against kidney grafts.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4249-60.
2009: Alberto Mantovani; Cecilia Garlanda; Massimo Locati
Macrophage diversity and polarization in atherosclerosis: a question of balance.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(10):1419-23.
2009: Maciej Lech; Alejandro Avila-Ferrufino; Ramanjaneyulu Allam; Stephan Segerer; Andrej Khandoga; Fritz Krombach; Cecilia Garlanda; Alberto Mantovani; Hans-Joachim Anders
Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(6):4109-18.
2009: Federica Riva; Nadia Polentarutti; Giulia Tribbioli; Alberto Mantovani; Cecilia Garlanda; Lauretta Turin
The expression pattern of TIR8 is conserved among vertebrates.
Veterinary immunology and immunopathology 2009;131(1-2):44-9.
2009: Cecilia Garlanda; Hans-Joachim Anders; Alberto Mantovani
TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization.
Trends in immunology 2009;30(9):439-46.
2009: Giuseppe D Norata; Patrizia Marchesi; Vivek Krishna Pulakazhi Venu; Fabio Pasqualini; Achille Anselmo; FEDERICA MOALLI; Irene Pizzitola; Cecilia Garlanda; Alberto Mantovani; Alberico Luigi Catapano
Deficiency of the long pentraxin PTX3 promotes vascular inflammation and atherosclerosis.
Circulation 2009;120(8):699-708.
2009: Francesco Colotta; Paola Allavena; Antonio Sica; Cecilia Garlanda; Alberto Mantovani
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability.
Carcinogenesis 2009;30(7):1073-81.
2009: Virginia Maina; Alessia Cotena; Andrea Doni; Manuela Nebuloni; Fabio Pasqualini; Caroline M Milner; Anthony J Day; Alberto Mantovani; Cecilia Garlanda
Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6.
Journal of leukocyte biology 2009;86(1):123-32.
2009: Jiri F P Wagenaar; Marga G A Goris; M Hussein Gasem; Bambang Isbandrio; FEDERICA MOALLI; Alberto Mantovani; Kimberly R Boer; Rudy A Hartskeerl; Cecilia Garlanda; Eric C M van Gorp
Long pentraxin PTX3 is associated with mortality and disease severity in severe Leptospirosis.
The Journal of infection 2009;58(6):425-32.
2009: Andrea Doni; Alessio Paffoni; Manuela Nebuloni; Guido Ragni; Fabio Pasqualini; Sonia Valentino; Silvia Bonetti; Alberto Mantovani; Edgardo Somigliana; Cecilia Garlanda
The long pentraxin 3 is a soluble and cell-associated component of the human semen.
International journal of andrology 2009;32(3):255-64.
2009: Alberto Mantovani; Antonio Sica; Paola Allavena; Cecilia Garlanda; Massimo Locati
Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation.
Human immunology 2009;70(5):325-30.
2009: Livija Deban; Barbara Bottazzi; Cecilia Garlanda; Yeny Martinez de la Torre; Alberto Mantovani
Pentraxins: multifunctional proteins at the interface of innate immunity and inflammation.
BioFactors (Oxford, England) 2009;35(2):138-45.
2009: Alok Agrawal; Prem Prakash Singh; Barbara Bottazzi; Cecilia Garlanda; Alberto Mantovani
Pattern recognition by pentraxins.
Advances in experimental medicine and biology 2009;653():98-116.
2009: Irene Cetin; Valeria Cozzi; Aris T Papageorghiou; Virginia Maina; Alessandro Montanelli; Cecilia Garlanda; Basky Thilaganathan
First trimester PTX3 levels in women who subsequently develop preeclampsia and fetal growth restriction.
Acta obstetricia et gynecologica Scandinavica 2009;88(7):846-9.
2009: Barbara Bottazzi; Cecilia Garlanda; Alessia Cotena; FEDERICA MOALLI; Sebastien Jaillon; Livija Deban; Alberto Mantovani
The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity.
Immunological reviews 2009;227(1):9-18.
2008: Hui Wan; Cornelia G Van Helden-Meeuwsen; Cecilia Garlanda; Lonneke M E Leijten; virginia maina; Nisar A Khan; Hemmo Drexhage; Alberto Mantovani; Robbert Benner; Marjan A Versnel
Chorionic gonadotropin up-regulates long pentraxin 3 expression in myeloid cells.
Journal of leukocyte biology 2008;84(5):1346-52.
2008: angelo manfredi; Patrizia Rovere-Querini; Barbara Bottazzi; Cecilia Garlanda; Alberto Mantovani
Pentraxins, humoral innate immunity and tissue injury.
Current opinion in immunology 2008;20(5):538-44.
2008: Maciej Lech; Onkar P Kulkarni; Stephanie Pfeiffer; Emina Savarese; Anne Krug; Cecilia Garlanda; Alberto Mantovani; Hans-Joachim Anders
Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.
The Journal of experimental medicine 2008;205(8):1879-88.
2008: Ceire Costelloe; Melanie Watson; Aine Murphy; Keith McQuillan; Christine Loscher; Michelle E Armstrong; Cecilia Garlanda; Alberto Mantovani; Luke A J O'Neill; Kingston H G Mills; Marina A Lynch
IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8.
Journal of neurochemistry 2008;105(5):1960-9.
2008: Giuseppe D Norata; Patrizia Marchesi; Angela Pirillo; Patrizia Uboldi; Giulia Chiesa; virginia maina; Cecilia Garlanda; Alberto Mantovani; Alberico L Catapano
Long pentraxin 3, a key component of innate immunity, is modulated by high-density lipoproteins in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):925-31.
2008: Paola Allavena; Antonio Sica; Cecilia Garlanda; Alberto Mantovani
The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance.
Immunological reviews 2008;222():155-61.
2008: Silvia Bozza; Teresa Zelante; Silvia Moretti; Pierluigi Bonifazi; Antonella DeLuca; Carmen D'Angelo; Gloria Giovannini; Cecilia Garlanda; Louis Boon; Francesco Bistoni; Paolo Puccetti; Alberto Mantovani; Luigina Romani
Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(6):4022-31.
2008: Roxana M Popovici; Miriam S Krause; Julia Jauckus; Ariane Germeyer; Ilma Simoni Brum; Cecilia Garlanda; Thomas Strowitzki; Michael Von Wolff
The long pentraxin PTX3 in human endometrium: regulation by steroids and trophoblast products.
Endocrinology 2008;149(3):1136-43.
2008: Monica Salio; Stefano Chimenti; Noeleen De Angelis; Fabiola Molla; virginia maina; Manuela Nebuloni; Fabio Pasqualini; Roberto Latini; Cecilia Garlanda; Alberto Mantovani
Cardioprotective function of the long pentraxin PTX3 in acute myocardial infarction.
Circulation 2008;117(8):1055-64.
2008: Paola Allavena; Cecilia Garlanda; Maria Grazia Borrello; Antonio Sica; Alberto Mantovani
Pathways connecting inflammation and cancer.
Current opinion in genetics & development 2008;18(1):3-10.
2008: Alberto Mantovani; Cecilia Garlanda; Andrea Doni; Barbara Bottazzi
Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3.
Journal of clinical immunology 2008;28(1):1-13.
2007: Alberto Mantovani; Cecilia Garlanda; Massimo Locati; Tania Veliz Rodriguez; Safiye Gonzalvo Feo; Benedetta Savino; Annunciata Vecchi
Regulatory pathways in inflammation.
Autoimmunity reviews 2007;7(1):8-11.
2007: Alessia Cotena; virginia maina; Marina Sironi; Barbara Bottazzi; Pascale Jeannin; Annunciata Vecchi; Nathalie Corvaia; Mohamed R Daha; Alberto Mantovani; Cecilia Garlanda
Complement dependent amplification of the innate response to a cognate microbial ligand by the long pentraxin PTX3.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6311-7.
2007: Cecilia Garlanda; Diana Di Liberto; Annunciata Vecchi; Marco Pio La Manna; Chiara Buracchi; Nadia Caccamo; Alfredo Salerno; Francesco Dieli; Alberto Mantovani
Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by Toll IL-1 receptor 8/single Ig IL-1-related receptor, a negative regulator of IL-1/TLR signaling.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):3119-25.
2007: Cecilia Garlanda; Federica Riva; Tania Veliz; Nadia Polentarutti; Fabio Pasqualini; Enrico Radaelli; Marina Sironi; Manuela Nebuloni; Elisabetta Omodeo Zorini; Eugenio Scanziani; Alberto Mantovani
Increased susceptibility to colitis-associated cancer of mice lacking TIR8, an inhibitory member of the interleukin-1 receptor family.
Cancer research 2007;67(13):6017-21.
2007: Sébastien Jaillon; Giuseppe Peri; Yves Delneste; Isabelle Frémaux; Andrea Doni; FEDERICA MOALLI; Cecilia Garlanda; Luigina Romani; Hugues Gascan; Silvia Bellocchio; Silvia Bozza; Marco A Cassatella; Pascale Jeannin; Alberto Mantovani
The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps.
The Journal of experimental medicine 2007;204(4):793-804.
2006: Silvia Bozza; Francesco Bistoni; Roberta Gaziano; Lucia Pitzurra; Teresa Zelante; Pierluigi Bonifazi; Katia Perruccio; Silvia Bellocchio; Mariella Neri; Anna Maria Iorio; Giovanni Salvatori; Rita De Santis; Mario Calvitti; Andrea Doni; Cecilia Garlanda; Alberto Mantovani; Luigina Romani
Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation.
Blood 2006;108(10):3387-96.
2006: Alberto Mantovani; Cecilia Garlanda; Barbara Bottazzi; Giuseppe Peri; Andrea Doni; Yeny Martinez de la Torre; Roberto Latini
The long pentraxin PTX3 in vascular pathology.
Vascular pharmacology 2006;45(5):326-30.
2006: Antonio Inforzato; Giuseppe Peri; Andrea Doni; Cecilia Garlanda; Alberto Mantovani; Antonio Bastone; Andrea Carpentieri; Angela Amoresano; Piero Pucci; Anja Roos; Mohamed R Daha; Silvia Vincenti; Grazia Gallo; Paolo Carminati; Rita De Santis; Giovanni Salvatori
Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.
Biochemistry 2006;45(38):11540-51.
2006: Irene Cetin; Valeria Cozzi; Fabio Pasqualini; Manuela Nebuloni; Cecilia Garlanda; Luca Vago; Giorgio Pardi; Alberto Mantovani
Elevated maternal levels of the long pentraxin 3 (PTX3) in preeclampsia and intrauterine growth restriction.
American journal of obstetrics and gynecology 2006;194(5):1347-53.
2006: Barbara Bottazzi; Antonio Bastone; Andrea Doni; Cecilia Garlanda; Sonia Valentino; Livija Deban; virginia maina; Alessia Cotena; FEDERICA MOALLI; Luca Vago; Antonietta Salustri; Luigina Romani; Alberto Mantovani
The long pentraxin PTX3 as a link among innate immunity, inflammation, and female fertility.
Journal of leukocyte biology 2006;79(5):909-12.
2006: Alessio Paffoni; Guido Ragni; Andrea Doni; Edgardo Somigliana; Fabio Pasqualini; Liliana Restelli; Giorgio Pardi; Alberto Mantovani; Cecilia Garlanda
Follicular fluid levels of the long pentraxin PTX3.
Journal of the Society for Gynecologic Investigation 2006;13(3):226-31.
2006: Andrea Doni; Mosca Michela; Barbara Bottazzi; Giuseppe Peri; Sonia Valentino; Nadia Polentarutti; Cecilia Garlanda; Alberto Mantovani
Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL-10 and inhibition by IFN-gamma.
Journal of leukocyte biology 2006;79(4):797-802.
2006: Barbara Bottazzi; Cecilia Garlanda; Giovanni Salvatori; Pascale Jeannin; angelo manfredi; Alberto Mantovani
Pentraxins as a key component of innate immunity.
Current opinion in immunology 2006;18(1):10-5.
2006: Cecilia Garlanda; Barbara Bottazzi; Giovanni Salvatori; Rita De Santis; Alessia Cotena; Livija Deban; virginia maina; FEDERICA MOALLI; Andrea Doni; Tania Veliz-Rodriguez; Alberto Mantovani
Pentraxins in innate immunity and inflammation.
Novartis Foundation symposium 2006;279():80-6; discussion 86-91, 216-9.
2005: Pascale Jeannin; Barbara Bottazzi; Marina Sironi; Andrea Doni; MARCO RUSNATI; Marco Presta; virginia maina; Giovanni Magistrelli; Jean-François Haeuw; guillaume hoeffel; Nathalie Thieblemont; Nathalie Corvaia; Cecilia Garlanda; Yves Delneste; Alberto Mantovani
Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors.
Immunity 2005;22(5):551-60.
2005: Cecilia Garlanda; Barbara Bottazzi; Antonio Bastone; Alberto Mantovani
Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility.
Annual review of immunology 2005;23():337-66.
2004: Annalisa Del Prete; William Vermi; Erica Dander; Karel Otero; Laura Barberis; Walter Luini; Sergio Bernasconi; Marina Sironi; Amerigo Santoro; Cecilia Garlanda; Fabio Facchetti; Matthias P Wymann; Annunciata Vecchi; Emilio Hirsch; Alberto Mantovani; Silvano Sozzani
Defective dendritic cell migration and activation of adaptive immunity in PI3Kgamma-deficient mice.
The EMBO journal 2004;23(17):3505-15.
2004: Alberto Mantovani; Massimo Locati; Nadia Polentarutti; Annunciata Vecchi; Cecilia Garlanda
Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR.
Journal of leukocyte biology 2004;75(5):738-42.
2004: Antonietta Salustri; Cecilia Garlanda; Emilio Hirsch; Marika De Acetis; Alessia Maccagno; Barbara Bottazzi; Andrea Doni; Antonio Bastone; Giovanna Mantovani; Paolo Beck-Peccoz; Giovanni Salvatori; David J Mahoney; Anthony J Day; Gregorio Siracusa; Luigina Romani; Alberto Mantovani
PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization.
Development (Cambridge, England) 2004;131(7):1577-86.
2004: Cecilia Garlanda; Federica Riva; Nadia Polentarutti; Chiara Buracchi; Marina Sironi; Maida De Bortoli; Marta Muzio; Raffaella Bergottini; Eugenio Scanziani; Annunciata Vecchi; Emilio Hirsch; Alberto Mantovani
Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(10):3522-6.
2003: Nadia Polentarutti; Giselle Penton Rol; Marta Muzio; Daniela Bosisio; Marco Camnasio; Federica Riva; Carla Zoja; Ariela Benigni; Susanna Tomasoni; Annunciata Vecchi; Cecilia Garlanda; Alberto Mantovani
Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR.
European cytokine network 2003;14(4):211-8.
2003: Andrea Doni; Giuseppe Peri; Marcello Chieppa; Paola Allavena; Fabio Pasqualini; Luca Vago; Luigina Romani; Cecilia Garlanda; Alberto Mantovani
Production of the soluble pattern recognition receptor PTX3 by myeloid, but not plasmacytoid, dendritic cells.
European journal of immunology 2003;33(10):2886-93.
2003: Alberto Mantovani; Cecilia Garlanda; Barbara Bottazzi
Pentraxin 3, a non-redundant soluble pattern recognition receptor involved in innate immunity.
Vaccine 2003;21 Suppl 2():S43-7.
2002: Cecilia Garlanda; Emilio Hirsch; Silvia Bozza; Antonietta Salustri; Marika De Acetis; Rachele Nota; Alessia Maccagno; Federica Riva; Barbara Bottazzi; Giuseppe Peri; Andrea Doni; Luca Vago; Marina Botto; Rita De Santis; Paolo Carminati; Gregorio Siracusa; Fiorella Altruda; Annunciata Vecchi; Luigina Romani; Alberto Mantovani
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response.
Nature 2002;420(6912):182-6.
2002: Michael S Rolph; Sabine Zimmer; Barbara Bottazzi; Cecilia Garlanda; Alberto Mantovani; Göran K Hansson
Production of the long pentraxin PTX3 in advanced atherosclerotic plaques.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(5):e10-4.
2001: Teresa Ravizza; Daniela Moneta; Barbara Bottazzi; Giuseppe Peri; Cecilia Garlanda; E Hirsch; G J Richards; A Mantovani; Annamaria Vezzani
Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegeneration.
Neuroscience 2001;105(1):43-53.
2001: Alberto Mantovani; Marta Muzio; Cecilia Garlanda; Silvano Sozzani; Paola Allavena
Macrophage control of inflammation: negative pathways of regulation of inflammatory cytokines.
Novartis Foundation symposium 2001;234():120-31; discussion 131-5.
2000: Patrizia Rovere-Querini; Giuseppe Peri; Fausto Fazzini; Barbara Bottazzi; Andrea Doni; Attilio Bondanza; Valérie S Zimmermann; Cecilia Garlanda; Umberto Fascio; Maria Grazia Sabbadini; Claudio Rugarli; Alberto Mantovani; angelo manfredi
The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells.
Blood 2000;96(13):4300-6.
2000: Emilio Hirsch; VL Katanaev; Cecilia Garlanda; Ornella Azzolino; Luciano Pirola; Lorenzo Silengo; S Sozzani; A Mantovani; Fiorella Altruda; Matthias P Wymann
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.
Science (New York, N.Y.) 2000;287(5455):1049-53.
1999: Alberto Mantovani; Cecilia Garlanda
Novel pathways for negative regulation of inflammatory cytokines centered on receptor expression.
Developments in biological standardization 1999;97():97-104.
1999: Cecilia Garlanda
Purification through affinity chromatography and microsequencing.
Methods in molecular biology (Clifton, N.J.) 1999;96():29-37.
1998: A Mantovani; Cecilia Garlanda; M Introna; Annunciata Vecchi
Regulation of endothelial cell function by pro- and anti-inflammatory cytokines.
Transplantation proceedings 1998;30(8):4239-43.
1998: F Fioretti; Didier Fradelizi; Antonella Stoppacciaro; S Ramponi; Luigi Ruco; A Minty; Silvano Sozzani; Cecilia Garlanda; Annunciata Vecchi; Alberto Mantovani
Reduced tumorigenicity and augmented leukocyte infiltration after monocyte chemotactic protein-3 (MCP-3) gene transfer: perivascular accumulation of dendritic cells in peritumoral tissue and neutrophil recruitment within the tumor.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):342-6.
1997: Q G Dong; Sergio Bernasconi; S Lostaglio; R W De Calmanovici; Ines Martin-Padura; F Breviario; Cecilia Garlanda; S Ramponi; Alberto Mantovani; Annunciata Vecchi
A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(8):1599-604.
1997: Cecilia Garlanda; R Berthier; J Garin; Antonella Stoppacciaro; Luigi Ruco; D Vittet; D Gulino; C Matteucci; Alberto Mantovani; Annunciata Vecchi; Elisabetta Dejana
Characterization of MEC 14.7, a new monoclonal antibody recognizing mouse CD34: a useful reage for identifying and characterizing blood vessels and hematopoietic precursors.
European journal of cell biology 1997;73(4):368-77.
1996: Q G Dong; Andrea Graziani; Cecilia Garlanda; R W De Calmanovici; M Arese; R Soldi; Annunciata Vecchi; A Mantovani; Federico Bussolino
Anti-tumor activity of cytokines against opportunistic vascular tumors in mice.
International journal of cancer. Journal international du cancer 1996;65(5):700-8.
1994: Cecilia Garlanda; C Parravicini; M Sironi; M De Rossi; R Wainstok de Calmanovici; F Carozzi; Federico Bussolino; F Colotta; A Mantovani; Annunciata Vecchi
Progressive growth in immunodeficient mice and host cell recruitment by mouse endothelial cells transformed by polyoma middle-sized T antigen: implications for the pathogenesis of opportunistic vascular tumors.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7291-5.
1994: Annunciata Vecchi; Cecilia Garlanda; Maria Grazia Lampugnani; M Resnati; C Matteucci; Antonella Stoppacciaro; H Schnurch; W Risau; Luigi Ruco; A Mantovani
Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium.
European journal of cell biology 1994;63(2):247-54.