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Tina Garofalo

Research Profile

Chemicals & Drugs

Anatomy

Procedures

Disorders

Antiphospholipid Syndrome

Physiology

Signal Transduction

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Publications

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Laura Ciarlo; Lucrezia Gambardella; Tina Garofalo; Maria Grasso; Valeria Manganelli; Matteo Marconi; Paola Matarrese; Roberta Misasi; Maurizio Sorice; Antonella Tinari; Walter Malorni
Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease.
Maurizio Sorice; Vincenzo Tasciotti; Tina Garofalo; Valeria Manganelli; Vincenzo Mattei; Roberta Misasi
Trafficking of PrPc to mitochondrial raft-like microdomains during cell apoptosis.
Antonella Capozzi; Tina Garofalo; Maria Grasso; Emanuela Lococo; Agostina Longo; Roberta Misasi; Maurizio Sorice
Detection of antiphospholipid antibodies by automated chemiluminescence assay.

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All Publications

2012: Laura Ciarlo; Lucrezia Gambardella; Tina Garofalo; Maria Grasso; Valeria Manganelli; Matteo Marconi; Paola Matarrese; Roberta Misasi; Maurizio Sorice; Antonella Tinari; Walter Malorni
Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease.
Journal of lipid research 2012;53(10):2057-68.
2012: Maurizio Sorice; Vincenzo Tasciotti; Tina Garofalo; Valeria Manganelli; Vincenzo Mattei; Roberta Misasi
Trafficking of PrPc to mitochondrial raft-like microdomains during cell apoptosis.
Prion 2012;6(4):354-8.
2012: Antonella Capozzi; Tina Garofalo; Maria Grasso; Emanuela Lococo; Agostina Longo; Roberta Misasi; Maurizio Sorice
Detection of antiphospholipid antibodies by automated chemiluminescence assay.
Journal of immunological methods 2012;379(1-2):48-52.
2012: Maurizio Sorice; Rosa Vona; Tina Garofalo; Valeria Manganelli; Roberta Misasi; Walter Malorni
Ganglioside GD3 as a raft component in cell death regulation.
Anti-cancer agents in medicinal chemistry 2012;12(4):376-82.
2012: Maurizio Sorice; Vincenzo Tasciotti; Antonella Tinari; Laura Ciarlo; Lucrezia Gambardella; Tina Garofalo; Valeria Manganelli; Paola Matarrese; Vincenzo Mattei; Roberta Misasi; Walter Malorni
Dynamics of mitochondrial raft-like microdomains in cell life and death.
Communicative & integrative biology 2012;5(2):217-9.
2012: F Conti; Tina Garofalo; G R V Hughes; Munther A Khamashta; A Longo; Roberta Misasi; M Sorice; Cristiano Alessandri; D Bompane; A Capozzi; Guido Valesini
Thin-layer chromatography immunostaining in detecting anti-phospholipid antibodies in seronegative anti-phospholipid syndrome.
Clinical and experimental immunology 2012;167(3):429-37.
2011: Vincenzo Mattei; Roberta Misasi; Vincenzo Tasciotti; Antonella Tinari; Laura Ciarlo; Lucrezia Gambardella; Tina Garofalo; Walter Malorni; Valeria Manganelli; Paola Matarrese; Maurizio Sorice
Recruitment of cellular prion protein to mitochondrial raft-like microdomains contributes to apoptosis execution.
Molecular biology of the cell 2011;22(24):4842-53.
2010: Elena Ortona; Antonella Capozzi; Tania Colasanti; Fabrizio Conti; Cristiano Alessandri; Agostina Longo; Tina Garofalo; Paola Margutti; Roberta Misasi; Munther A Khamashta; Graham R V Hughes; Guido Valesini; Maurizio Sorice
Vimentin/cardiolipin complex as a new antigenic target of the antiphospholipid syndrome.
Blood 2010;116(16):2960-7.
2010: L Ciarlo; V Manganelli; Tina Garofalo; Paola Matarrese; Antonella Tinari; Roberta Misasi; Walter Malorni; Maurizio Sorice
Association of fission proteins with mitochondrial raft-like domains.
Cell death and differentiation 2010;17(6):1047-58.
2010: Maurizio Sorice; Paola Matarrese; Valeria Manganelli; Antonella Tinari; Anna Maria Giammarioli; Vincenzo Mattei; Roberta Misasi; Tina Garofalo; Walter Malorni
Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis triggered by CD95/Fas.
PloS one 2010;5(1):e8567.
2009: Maurizio Sorice; Paola Matarrese; Antonella Tinari; Anna Maria Giammarioli; Tina Garofalo; Valeria Manganelli; Laura Ciarlo; Lucrezia Gambardella; Giorgio Maccari; Maurizio Botta; Roberta Misasi; Walter Malorni
Raft component GD3 associates with tubulin following CD95/Fas ligation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(10):3298-308.
2009: Maurizio Sorice; Valeria Manganelli; Paola Matarrese; Antonella Tinari; Roberta Misasi; Walter Malorni; Tina Garofalo
Cardiolipin-enriched raft-like microdomains are essential activating platforms for apoptotic signals on mitochondria.
FEBS letters 2009;583(15):2447-50.
2008: Paola Matarrese; Valeria Manganelli; Tina Garofalo; Antonella Tinari; Lucrezia Gambardella; Kenneth Ndebele; Roya Khosravi-Far; Maurizio Sorice; Mauro Degli Esposti; Walter Malorni
Endosomal compartment contributes to the propagation of CD95/Fas-mediated signals in type II cells.
The Biochemical journal 2008;413(3):467-78.
2008: Paola Margutti; Paola Matarrese; Fabrizio Conti; Tania Colasanti; Federica Delunardo; Antonella Capozzi; Tina Garofalo; Elisabetta Profumo; Rachele Riganò; Alessandra Siracusano; Cristiano Alessandri; Bruno Salvati; Guido Valesini; Walter Malorni; Maurizio Sorice; Elena Ortona
Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis.
Blood 2008;111(9):4559-70.
2008: Walter Malorni; Tina Garofalo; Antonella Tinari; Valeria Manganelli; Roberta Misasi; Maurizio Sorice
Analyzing lipid raft dynamics during cell apoptosis.
Methods in enzymology 2008;442():125-40.
2007: Tina Garofalo; Antonella Tinari; Paola Matarrese; Anna Maria Giammarioli; Valeria Manganelli; Laura Ciarlo; Roberta Misasi; Maurizio Sorice; Walter Malorni
Do mitochondria act as "cargo boats" in the journey of GD3 to the nucleus during apoptosis?
FEBS letters 2007;581(21):3899-903.
2007: Maurizio Sorice; Agostina Longo; Antonella Capozzi; Tina Garofalo; Roberta Misasi; Cristiano Alessandri; Fabrizio Conti; Brigitta Buttari; Rachele Riganò; Elena Ortona; Guido Valesini
Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts.
Arthritis and rheumatism 2007;56(8):2687-97.
2007: Walter Malorni; Anna Maria Giammarioli; Tina Garofalo; Maurizio Sorice
Dynamics of lipid raft components during lymphocyte apoptosis: the paradigmatic role of GD3.
Apoptosis : an international journal on programmed cell death 2007;12(5):941-9.
2007: Antonella Tinari; Tina Garofalo; Maurizio Sorice; Mauro Degli Esposti; Walter Malorni
Mitoptosis: different pathways for mitochondrial execution.
Autophagy 2007;3(3):282-4.
2007: Christiane Barbat; Maylis Trucy; Maurizio Sorice; Tina Garofalo; Valeria Manganelli; Alain Fischer; Fabienne Mazerolles
p56lck, LFA-1 and PI3K but not SHP-2 interact with GM1- or GM3-enriched microdomains in a CD4-p56lck association-dependent manner.
The Biochemical journal 2007;402(3):471-81.
2006: Elena Sottocornola; Roberta Misasi; Vincenzo Mattei; Laura Ciarlo; Roberto Gradini; Tina Garofalo; Bruno Berra; Irma Colombo; Maurizio Sorice
Role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells.
The FEBS journal 2006;273(8):1821-30.
2006: Cristiano Alessandri; Maurizio Sorice; Michele Bombardieri; Paola Conigliaro; Agostina Longo; Tina Garofalo; Valeria Manganelli; Fabrizio Conti; Mauro Degli Esposti; Guido Valesini
Antiphospholipid reactivity against cardiolipin metabolites occurring during endothelial cell apoptosis.
Arthritis research & therapy 2006;8(6):R180.
2005: Maria Isabella Sirinian; Francesca Belleudi; Filomena Campagna; Mara Ceridono; Tina Garofalo; Fabiana Quagliarini; Roberto Verna; Sebastiano Calandra; Stefano Bertolini; Maurizio Sorice; Maria Rosaria Torrisi; Marcello Arca
Adaptor protein ARH is recruited to the plasma membrane by low density lipoprotein (LDL) binding and modulates endocytosis of the LDL/LDL receptor complex in hepatocytes.
The Journal of biological chemistry 2005;280(46):38416-23.
2005: Tina Garofalo; Anna Maria Giammarioli; Roberta Misasi; Antonella Tinari; Valeria Manganelli; Lucrezia Gambardella; Antonio Pavan; Walter Malorni; Maurizio Sorice
Lipid microdomains contribute to apoptosis-associated modifications of mitochondria in T cells.
Cell death and differentiation 2005;12(11):1378-89.
2004: Maurizio Sorice; Annapia Circella; Ileana M Cristea; Tina Garofalo; Livia Di Renzo; Cristiano Alessandri; Guido Valesini; Mauro Degli Esposti
Cardiolipin and its metabolites move from mitochondria to other cellular membranes during death receptor-mediated apoptosis.
Cell death and differentiation 2004;11(10):1133-45.
2004: Roberta Misasi; Tina Garofalo; Luisa Di Marzio; Vincenzo Mattei; Chiara Gizzi; Masao Hiraiwa; Antonio Pavan; Maria Grazia Cifone; Maurizio Sorice
Prosaposin: a new player in cell death prevention of U937 monocytic cells.
Experimental cell research 2004;298(1):38-47.
2004: Vincenzo Mattei; Tina Garofalo; Roberta Misasi; Annapia Circella; Valeria Manganelli; Giuseppe Lucania; Antonio Pavan; Maurizio Sorice
Prion protein is a component of the multimolecular signaling complex involved in T cell activation.
FEBS letters 2004;560(1-3):14-8.
2004: Maurizio Sorice; Agostina Longo; Tina Garofalo; Vincenzo Mattei; Roberta Misasi; Antonio Pavan
Role of GM3-enriched microdomains in signal transduction regulation in T lymphocytes.
Glycoconjugate journal 2004;20(1):63-70.
2003: Tina Garofalo; Roberta Misasi; Vincenzo Mattei; Anna Maria Giammarioli; Walter Malorni; Giuseppe M Pontieri; Antonio Pavan; Maurizio Sorice
Association of the death-inducing signaling complex with microdomains after triggering through CD95/Fas. Evidence for caspase-8-ganglioside interaction in T cells.
The Journal of biological chemistry 2003;278(10):8309-15.
2002: Vincenzo Mattei; Tina Garofalo; Roberta Misasi; Chiara Gizzi; Maria Teresa Mascellino; Vincenza Dolo; Giuseppe M Pontieri; Maurizio Sorice; Antonio Pavan
Association of cellular prion protein with gangliosides in plasma membrane microdomains of neural and lymphocytic cells.
Neurochemical research 2002;27(7-8):743-9.
2002: Tina Garofalo; Maurizio Sorice; Roberta Misasi; Benedetta Cinque; Vincenzo Mattei; Giuseppe M Pontieri; Maria Grazia Cifone; Antonio Pavan
Ganglioside GM3 activates ERKs in human lymphocytic cells.
Journal of lipid research 2002;43(6):971-8.
2002: Maurizio Sorice; Domenico Ferro; Roberta Misasi; Valerio Pittoni; Agostina Longo; Annapia Circella; Tina Garofalo; Roberto Gradini; Francesco Violi; J Gruenberg; Guido Valesini
Evidence for anticoagulant activity and beta2-GPI accumulation in late endosomes of endothelial cells induced by anti-LBPA antibodies.
Thrombosis and haemostasis 2002;87(4):735-41.
2002: Tina Garofalo; Luisa Lenti; Agostina Longo; Roberta Misasi; Vincenzo Mattei; Giuseppe M Pontieri; Antonio Pavan; Maurizio Sorice
Association of GM3 with Zap-70 induced by T cell activation in plasma membrane microdomains: GM3 as a marker of microdomains in human lymphocytes.
The Journal of biological chemistry 2002;277(13):11233-8.
2001: Maurizio Sorice; Tina Garofalo; Roberta Misasi; Agostina Longo; Vincenzo Mattei; sale Patrizio; Vincenza Dolo; Roberto Gradini; Antonio Pavan
Evidence for cell surface association between CXCR4 and ganglioside GM3 after gp120 binding in SupT1 lymphoblastoid cells.
FEBS letters 2001;506(1):55-60.
2001: Anna Maria Giammarioli; Tina Garofalo; Maurizio Sorice; Roberta Misasi; Lucrezia Gambardella; Roberto Gradini; Stefano Fais; Antonio Pavan; Walter Malorni
GD3 glycosphingolipid contributes to Fas-mediated apoptosis via association with ezrin cytoskeletal protein.
FEBS letters 2001;506(1):45-50.
2001: Federico Bordi; Cesare Cametti; F De Luca; T Gili; Roberta Misasi; Maurizio Sorice; Annapia Circella; Tina Garofalo
Structural alteration of erythrocyte membrane during storage: a combined electrical conductometric and flow-cytometric study.
Zeitschrift für Naturforschung. C, Journal of biosciences 2001;56(9-10):857-64.
2000: Maurizio Sorice; Annapia Circella; Roberta Misasi; Valerio Pittoni; Tina Garofalo; Augusto Cirelli; Antonio Pavan; Giuseppe M Pontieri; Guido Valesini
Cardiolipin on the surface of apoptotic cells as a possible trigger for antiphospholipids antibodies.
Clinical and experimental immunology 2000;122(2):277-84.
2000: Roberta Misasi; Maurizio Sorice; Tina Garofalo; Tamara Griggi; Anna Maria Giammarioli; Gabriella d'Ettorre; Vincenzo Vullo; Giuseppe M Pontieri; Walter Malorni; Antonio Pavan
Overexpression of lymphocytic GD3 ganglioside and presence of anti-GD3 antibodies in patients with HIV infection.
AIDS research and human retroviruses 2000;16(15):1539-49.
2000: Maurizio Sorice; Tina Garofalo; Roberta Misasi; Agostina Longo; J Mikulak; Vincenza Dolo; Giuseppe M Pontieri; Antonio Pavan
Association between GM3 and CD4-Ick complex in human peripheral blood lymphocytes.
Glycoconjugate journal 2000;17(3 -4):247-52.
2000: Roberta Priori; Fabrizio Conti; Valerio Pittoni; Tina Garofalo; Maurizio Sorice; Guido Valesini
Is there a role for anti-phospholipid-binding protein antibodies in the pathogenesis of thrombosis in Behcet's disease?
Thrombosis and haemostasis 2000;83(1):173-4.
2000: Vincenzo Visco; Giuseppe Lucania; T Sansolini; Vincenza Dolo; Tina Garofalo; Maurizio Sorice; Luigi Frati; Maria Rosaria Torrisi; Antonio Pavan
Expression of GM3 microdomains on the surfaces of murine fibroblasts correlates with inhibition of cell proliferation.
Histochemistry and cell biology 2000;113(1):43-50.
1999: Maurizio Sorice; Tina Garofalo; Roberta Misasi; Vincenza Dolo; Giuseppe Lucania; T Sansolini; Isabella Parolini; Massimo Sargiacomo; Maria Rosaria Torrisi; Antonio Pavan
Glycosphingolipid domains on cell plasma membrane.
Bioscience reports 1999;19(3):197-208.
1998: Tina Garofalo; Maurizio Sorice; Roberta Misasi; Benedetta Cinque; M Giammatteo; Giuseppe M Pontieri; Maria Grazia Cifone; Antonio Pavan
A novel mechanism of CD4 down-modulation induced by monosialoganglioside GM3. Involvement of serine phosphorylation and protein kinase c delta translocation.
The Journal of biological chemistry 1998;273(52):35153-60.
1998: Roberta Misasi; Maurizio Sorice; Tina Garofalo; Tamara Griggi; W Marie Campana; M Giammatteo; Antonio Pavan; Masao Hiraiwa; Giuseppe M Pontieri; John S O'Brien
Colocalization and complex formation between prosaposin and monosialoganglioside GM3 in neural cells.
Journal of neurochemistry 1998;71(6):2313-21.
1997: Maurizio Sorice; Isabella Parolini; T Sansolini; Tina Garofalo; Vincenza Dolo; Massimo Sargiacomo; T Tai; Cesare Peschle; Maria Rosaria Torrisi; Antonio Pavan
Evidence for the existence of ganglioside-enriched plasma membrane domains in human peripheral lymphocytes.
Journal of lipid research 1997;38(5):969-80.
1996: Maurizio Sorice; Tina Garofalo; T Sansolini; T Griggi; A Circella; A Massetti; T Tai; Antonio Pavan
Overexpression of monosialoganglioside GM3 on lymphocyte plasma membrane in patients with HIV infection.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;12(2):112-9.
1996: Maurizio Sorice; T Griggi; G Nicodemo; Tina Garofalo; Massimo Marangi; S Sanguigni; S I Becker; David Mirelman
Evidence for the existence of ganglioside molecules in the antigen of Entamoeba histolytica.
Parasite immunology 1996;18(3):133-7.
1996: Maurizio Sorice; A Circella; T Griggi; Tina Garofalo; G Nicodemo; Valerio Pittoni; Giuseppe M Pontieri; Luisa Lenti; Guido Valesini
Anticardiolipin and anti-beta 2-GPI are two distinct populations of autoantibodies.
Thrombosis and haemostasis 1996;75(2):303-8.
1995: Maurizio Sorice; Antonio Pavan; Roberta Misasi; T Sansolini; Tina Garofalo; Luisa Lenti; Giuseppe M Pontieri; Luigi Frati; Maria Rosaria Torrisi
Monosialoganglioside GM3 induces CD4 internalization in human peripheral blood T lymphocytes.
Scandinavian journal of immunology 1995;41(2):148-56.
1994: Maurizio Sorice; T Griggi; A Circella; Tina Garofalo; F d'Agostino; Valerio Pittoni; Giuseppe M Pontieri; Luisa Lenti; Guido Valesini
Detection of antiphospholipid antibodies by immunostaining on thin layer chromatography plates.
Journal of immunological methods 1994;173(1):49-54.
1994: T Griggi; R Bauer; Tina Garofalo; S Kukel; Luisa Lenti; A P Massetti; C Müller; Maurizio Sorice; Giuseppe M Pontieri
Autoantibodies against ganglioside GM3 represent a portion of anti-lymphocyte antibodies in AIDS patients.
Scandinavian journal of immunology 1994;40(1):77-82.
1993: Roberta Misasi; Maurizio Sorice; T Griggi; F d'Agostino; Tina Garofalo; C Masala; Giuseppe M Pontieri; Luisa Lenti
GM3 as a target of anti-lymphocytic ganglioside antibodies in AIDS patients.
Clinical immunology and immunopathology 1993;67(3 Pt 1):216-23.