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Leonardo Gaspa

Research Profile

Living Beings

Chemicals & Drugs

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Neovascularization, Physiologic

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Publications

TOP 3
Irene Marchesi; Valentina Nieddu; Valentina Caracciolo; Leonardo Gaspa; Antonio Giordano; Margherita Maioli; Luigi Bagella
Activation and function of murine Cyclin T2A and Cyclin T2B during skeletal muscle differentiation.
Salvatore Sotgia; Angelo Zinellu; Elisabetta Pisanu; Luciano Murgia; Gerard Aime Pinna; Leonardo Gaspa; Luca Deiana; Ciriaco Carru
A hydrophilic interaction ultraperformance liquid chromatography (HILIC-UPLC) method for genomic DNA methylation assessment by UV detection.
Valeria Pasciu; Anna Maria Posadino; Antonio Cossu; Bastiano Sanna; Bruna Tadolini; Leonardo Gaspa; Andrea Marchisio; Salvatore Dessole; Giampiero Capobianco; Gianfranco Pintus
Akt downregulation by flavin oxidase-induced ROS generation mediates dose-dependent endothelial cell damage elicited by natural antioxidants.

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All Publications

2013: Irene Marchesi; Valentina Nieddu; Valentina Caracciolo; Leonardo Gaspa; Antonio Giordano; Margherita Maioli; Luigi Bagella
Activation and function of murine Cyclin T2A and Cyclin T2B during skeletal muscle differentiation.
Journal of cellular biochemistry 2013;114(3):728-34.
2010: Salvatore Sotgia; Angelo Zinellu; Elisabetta Pisanu; Luciano Murgia; Gerard Aime Pinna; Leonardo Gaspa; Luca Deiana; Ciriaco Carru
A hydrophilic interaction ultraperformance liquid chromatography (HILIC-UPLC) method for genomic DNA methylation assessment by UV detection.
Analytical and bioanalytical chemistry 2010;396(8):2937-41.
2010: Valeria Pasciu; Anna Maria Posadino; Antonio Cossu; Bastiano Sanna; Bruna Tadolini; Leonardo Gaspa; Andrea Marchisio; Salvatore Dessole; Giampiero Capobianco; Gianfranco Pintus
Akt downregulation by flavin oxidase-induced ROS generation mediates dose-dependent endothelial cell damage elicited by natural antioxidants.
Toxicological sciences : an official journal of the Society of Toxicology 2010;114(1):101-12.
2010: Angelo Zinellu; Antonio Lepedda; Salvatore Sotgia; Elisabetta Zinellu; Giommaria Marongiu; Maria Franca Usai; Leonardo Gaspa; Pierina De Muro; Marilena Formato; Luca Deiana; Ciriaco Carru
Albumin-bound low molecular weight thiols analysis in plasma and carotid plaques by CE.
Journal of separation science 2010;33(1):126-31.
2009: Salvatore Sotgia; Ciriaco Carru; Bastianina Scanu; Elisabetta Pisanu; Manuela Sanna; Gerard Aime Pinna; Leonardo Gaspa; Luca Deiana; Angelo Zinellu
Improved rapid assay of plasma uric acid by short-end injection capillary zone electrophoresis.
Analytical and bioanalytical chemistry 2009;395(8):2577-82.
2009: Angelo Zinellu; Salvatore Sotgia; Bastianina Scanu; Scanu Bastianina; Roberto Chessa; Leonardo Gaspa; Flavia Franconi; Luca Deiana; Ciriaco Carru
Taurine determination by capillary electrophoresis with laser-induced fluorescence detection: from clinical field to quality food applications.
Amino acids 2009;36(1):35-41.
2008: Tiziana Tonini; Giuseppina D'Andrilli; Alfredo Fucito; Leonardo Gaspa; Luigi Bagella
Importance of Ezh2 polycomb protein in tumorigenesis process interfering with the pathway of growth suppressive key elements.
Journal of cellular physiology 2008;214(2):295-300.
2008: Angelo Zinellu; Antonio Pinna; Salvatore Sotgia; Elisabetta Zinellu; Maria Franca Usai; Francesco Carta; Leonardo Gaspa; Luca Deiana; Ciriaco Carru
Increased plasma asymmetric dimethylarginine (ADMA) levels in retinal venous occlusive disease.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2008;46(3):387-92.
2007: Angelo Zinellu; Salvatore Sotgia; Anna M Posadino; Valeria Pasciu; Elisabetta Zinellu; Maria Franca Usai; Bastianina Scanu; Roberto Chessa; Leonardo Gaspa; Bruna Tadolini; Luca Deiana; Ciriaco Carru
Protein-bound glutathione measurement in cultured cells by CZE with LIF detection.
Electrophoresis 2007;28(18):3277-83.
2007: Guglielmo Campus; Franklin Garcia-Godoy; Leonardo Gaspa; Angelo Panzanelli; Paola C Piu; Giovanni Micera; Pierfranca Lugliè; Gavino Sanna
Dependence of kinetic variables in the short-term release of Hg2+, Cu2+ and Zn2+ ions into synthetic saliva from an high-copper dental amalgam.
Journal of materials science. Materials in medicine 2007;18(8):1521-7.
2007: Angelo Zinellu; Salvatore Sotgia; Elisabetta Zinellu; Antonio Pinna; Francesco Carta; Leonardo Gaspa; Luca Deiana; Ciriaco Carru
High-throughput CZE-UV determination of arginine and dimethylated arginines in human plasma.
Electrophoresis 2007;28(12):1942-8.
2007: Angelo Zinellu; Salvatore Sotgia; Maria Franca Usai; Elisabetta Zinellu; Anna M Posadino; Leonardo Gaspa; Roberto Chessa; Antonio Pinna; Francesco Carta; Luca Deiana; Ciriaco Carru
Plasma methionine determination by capillary electrophoresis-UV assay: application on patients affected by retinal venous occlusive disease.
Analytical biochemistry 2007;363(1):91-6.
2002: Costanza Emanueli; Maria Bonaria Salis; Tiziana Stacca; Alessandra Pinna; Leonardo Gaspa; Alessandra Spano; Paolo Madeddu
Ramipril improves hemodynamic recovery but not microvascular response to ischemia in spontaneously hypertensive rats.
American journal of hypertension 2002;15(5):410-5.
2002: Costanza Emanueli; Maria Bonaria Salis; Tiziana Stacca; Gianfranco Pintus; Rudolf Kirchmair; Jeffrey M Isner; Alessandra Pinna; Leonardo Gaspa; Domenico Regoli; Cécile Cayla; João B Pesquero; Michael Bader; Paolo Madeddu
Targeting kinin B(1) receptor for therapeutic neovascularization.
Circulation 2002;105(3):360-6.
2002: Costanza Emanueli; Maria Bonaria Salis; Tiziana Stacca; Alessandra Pinna; Leonardo Gaspa; Paolo Madeddu; Paolo Maddeddu
Angiotensin AT(1) receptor signalling modulates reparative angiogenesis induced by limb ischaemia.
British journal of pharmacology 2002;135(1):87-92.
2001: Costanza Emanueli; Maria Bonaria Salis; Tiziana Stacca; Leonardo Gaspa; Julie Chao; Lee Chao; A Piana; Paolo Madeddu
Rescue of impaired angiogenesis in spontaneously hypertensive rats by intramuscular human tissue kallikrein gene transfer.
Hypertension 2001;38(1):136-41.
2001: Paolo Madeddu; Costanza Emanueli; Maria Bonaria Salis; A Franca Milia; Tiziana Stacca; L Carta; Alessandra Pinna; M Deiana; Leonardo Gaspa
Role of calcitonin gene-related peptide and kinins in post-ischemic intestinal reperfusion.
Peptides 2001;22(6):915-22.
2001: Costanza Emanueli; A Minasi; Antonella Zacheo; Julie Chao; Lee Chao; Maria Bonaria Salis; Stefania Straino; Maria Grazia Tozzi; R Smith; Leonardo Gaspa; G Bianchini; F Stillo; Maurizio C Capogrossi; Paolo Madeddu
Local delivery of human tissue kallikrein gene accelerates spontaneous angiogenesis in mouse model of hindlimb ischemia.
Circulation 2001;103(1):125-32.
2000: Costanza Emanueli; Maria Bonaria Salis; C Figueroa; Julie Chao; Lee Chao; Leonardo Gaspa; Maurizio C Capogrossi; Paolo Madeddu
Participation of kinins in the captopril-induced inhibition of intimal hyperplasia caused by interruption of carotid blood flow in the mouse.
British journal of pharmacology 2000;130(5):1076-82.
1999: Paolo Madeddu; Costanza Emanueli; Leonardo Gaspa; B Salis; Anna Franca Milia; Lee Chao; Julie Chao
Role of the bradykinin B2 receptor in the maturation of blood pressure phenotype: lesson from transgenic and knockout mice.
Immunopharmacology 1999;44(1-2):9-13.
1999: Gianfranco Pintus; Bruna Tadolini; Margherita Maioli; Anna M Posadino; Leonardo Gaspa; Carlo Ventura
Heparin down-regulates the phorbol ester-induced protein kinase C gene expression in human endothelial cells: enzyme-mediated autoregulation of protein kinase C-alpha and -delta genes.
FEBS letters 1999;449(2-3):135-40.
1998: Paolo Madeddu; Anna Franca Milia; Maria Bonaria Salis; Leonardo Gaspa; W Gross; Andrea Lippoldt; Costanza Emanueli
Renovascular hypertension in bradykinin B2-receptor knockout mice.
Hypertension 1998;32(3):503-9.
1998: Rosa M Pascale; Maria R De Miglio; Maria R Muroni; Maria M Simile; Lucia Daino; Maria A Seddaiu; S Pusceddu; Leonardo Gaspa; Diego F Calvisi; Giacomo Manenti; Francesco Feo
Transferrin and transferrin receptor gene expression and iron uptake in hepatocellular carcinoma in the rat.
Hepatology (Baltimore, Md.) 1998;27(2):452-61.
1997: Carlo Ventura; Gianfranco Pintus; M G Fiori; Federico Bennardini; G Pinna; Leonardo Gaspa
Opioid peptide gene expression in the primary hereditary cardiomyopathy of the Syrian hamster. I. Regulation of prodynorphin gene expression by nuclear protein kinase C.
The Journal of biological chemistry 1997;272(10):6685-92.
1996: Rosa M Pascale; Maria R De Miglio; Maria R Muroni; Maria M Simile; Lucia Daino; Maria A Seddaiu; A Nufris; Leonardo Gaspa; Luca Deiana; Francesco Feo
c-myc amplification in pre-malignant and malignant lesions induced in rat liver by the resistant hepatocyte model.
International journal of cancer. Journal international du cancer 1996;68(1):136-42.
1996: Rosa M Pascale; Maria M Simile; M R DeMiglio; Maria R Muroni; Leonardo Gaspa; T A Dragani; Francesco Feo
The BN rat strain carries dominant hepatocarcinogen resistance loci.
Carcinogenesis 1996;17(8):1765-8.
1994: Maria M Simile; Rosa M Pascale; Maria R De Miglio; A Nufris; Lucia Daino; Maria A Seddaiu; Leonardo Gaspa; Francesco Feo
Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis.
Cancer letters 1994;79(1):9-16.
1993: U Gerbracht; Erich Eigenbrodt; Maria M Simile; Rosa M Pascale; Leonardo Gaspa; Lucia Daino; Maria A Seddaiu; Maria R De Miglio; A Nufris; Francesco Feo
Effect of S-adenosyl-L-methionine on the development of preneoplastic foci and the activity of some carbohydrate metabolizing enzymes in the liver, during experimental hepatocarcinogenesis.
Anticancer research 1993;13(6A):1965-72.
1993: Rosa M Pascale; Maria M Simile; Leonardo Gaspa; Lucia Daino; Maria A Seddaiu; G Pinna; M Carta; P Zolo; Francesco Feo
Alterations of ornithine decarboxylase gene during the progression of rat liver carcinogenesis.
Carcinogenesis 1993;14(5):1077-80.
1993: Rosa M Pascale; Maria M Simile; Maria A Seddaiu; Lucia Daino; M A Vinci; G Pinna; S Bennati; Leonardo Gaspa; Francesco Feo
Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: is DNA methylation involved?
Basic life sciences 1993;61():219-37.
1991: Rosa M Pascale; Maria M Simile; G Satta; Maria A Seddaiu; Lucia Daino; G Pinna; M A Vinci; Leonardo Gaspa; Francesco Feo
Comparative effects of L-methionine, S-adenosyl-L-methionine and 5'-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early stages of hepatocarcinogenesis.
Anticancer research 1991;11(4):1617-24.
1989: R Garcea; Lucia Daino; Rosa M Pascale; Maria M Simile; M Puddu; S Frassetto; P Cozzolino; Maria A Seddaiu; Leonardo Gaspa; Francesco Feo
Inhibition of promotion and persistent nodule growth by S-adenosyl-L-methionine in rat liver carcinogenesis: role of remodeling and apoptosis.
Cancer research 1989;49(7):1850-6.
1987: Francesco Feo; M E Ruggiu; L Lenzerini; R Garcea; Lucia Daino; S Frassetto; V Addis; Leonardo Gaspa; Rosa M Pascale
Benzo(a)pyrene metabolism by lymphocytes from normal individuals and individuals carrying the Mediterranean variant of glucose-6-phosphate dehydrogenase.
International journal of cancer. Journal international du cancer 1987;39(5):560-4.
1987: R Garcea; Rosa M Pascale; Lucia Daino; S Frassetto; P Cozzolino; M E Ruggiu; M G Vannini; Leonardo Gaspa; Francesco Feo
Variations of ornithine decarboxylase activity and S-adenosyl-L-methionine and 5'-methylthioadenosine contents during the development of diethylnitrosamine-induced liver hyperplastic nodules and hepatocellular carcinoma.
Carcinogenesis 1987;8(5):653-8.
1984: Francesco Feo; Lucia Pirisi-Creek; Rosa M Pascale; Lucia Daino; S Frassetto; R Garcea; Leonardo Gaspa
Modulatory effect of glucose-6-phosphate dehydrogenase deficiency on benzo(a)pyrene toxicity and transforming activity for in vitro-cultured human skin fibroblasts.
Cancer research 1984;44(8):3419-25.
1982: Lucia Pirisi-Creek; Rosa M Pascale; Lucia Daino; S Frassetto; V La Spina; S Zanetti; Leonardo Gaspa; G M Ledda; R Garcea; Francesco Feo
Effect of glucose-6-phosphate dehydrogenase deficiency on the benz(a)pyrene toxicity for in vitro cultured human skin fibroblasts.
Research communications in chemical pathology and pharmacology 1982;38(2):301-11.