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Max Gassmann

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Isabelle Aeberli; Kaspar Berneis; Annina Erb; Graham S Finlayson; Mark Fox; Heiko Frühauf; Max Gassmann; Oliver Götze; Wolfgang Langhans; Marco Maggiorini; Daniela Meier; Kerstin Spliethoff; Thomas A Lutz
Disturbed eating at high altitude: influence of food preferences, acute mountain sickness and satiation hormones.
Elena Gammella; Max Gassmann; Caroline Leuenberger; Louise Ostergaard
Evidence of synergistic/additive effects of sildenafil and erythropoietin in enhancing survival and migration of hypoxic endothelial cells.
Sergej Yakushev; Aaron Avivi; Mark Band; Max Gassmann; Martha C Tissot van Patot; Anna Bogdanova
Cross talk between S-nitrosylation and S-glutathionylation in control of the Na,K-ATPase regulation in hypoxic heart.

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All Publications

2013: Isabelle Aeberli; Kaspar Berneis; Annina Erb; Graham S Finlayson; Mark Fox; Heiko Frühauf; Max Gassmann; Oliver Götze; Wolfgang Langhans; Marco Maggiorini; Daniela Meier; Kerstin Spliethoff; Thomas A Lutz
Disturbed eating at high altitude: influence of food preferences, acute mountain sickness and satiation hormones.
European journal of nutrition 2013;52(2):625-35.
2013: Elena Gammella; Max Gassmann; Caroline Leuenberger; Louise Ostergaard
Evidence of synergistic/additive effects of sildenafil and erythropoietin in enhancing survival and migration of hypoxic endothelial cells.
American journal of physiology. Lung cellular and molecular physiology 2013;304(4):L230-9.
2012: Sergej Yakushev; Aaron Avivi; Mark Band; Max Gassmann; Martha C Tissot van Patot; Anna Bogdanova
Cross talk between S-nitrosylation and S-glutathionylation in control of the Na,K-ATPase regulation in hypoxic heart.
American journal of physiology. Heart and circulatory physiology 2012;303(11):H1332-43.
2012: Irina Yu Petrushanko; Sergej Yakushev; Rustam H Ziganshin; Anastasiya A Anashkina; Max Gassmann; Yuliya V Kamanina; Olga D Lopina; Alexander A Makarov; Asya Makhro; Xianyu Meng; Vladmir Mitkevich; Anna Bogdanova
S-glutathionylation of the Na,K-ATPase catalytic α subunit is a determinant of the enzyme redox sensitivity.
The Journal of biological chemistry 2012;287(38):32195-205.
2012: Martha C Tissot van Patot; German Ebensperger; Max Gassmann; Aníbal J Llanos
The hypoxic placenta.
High altitude medicine & biology 2012;13(3):176-84.
2012: Beat Schuler; Johannes Vogel; Margarete Arras; Beat Grenacher; Robert A Jacobs; Max Gassmann
Acute and chronic elevation of erythropoietin in the brain improves exercise performance in mice without inducing erythropoiesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(9):3884-90.
2012: Robert A Jacobs; Carsten Lundby; Paul Robach; Max Gassmann
Red blood cell volume and the capacity for exercise at moderate to high altitude.
Sports medicine (Auckland, N.Z.) 2012;42(8):643-63.
2012: Nicolas Hümmler; Wolfgang Rascher; Christina Schneider; Reinhard Bauer; Max Gassmann; Andreas Giessl; Gail Walkinshaw; Regina Trollmann
Acute hypoxia modifies regulation of neuroglobin in the neonatal mouse brain.
Experimental neurology 2012;236(1):112-21.
2012: Christina Schneider; Max Gassmann; Gudrun Krischke; Wolfgang Rascher; Regina Trollmann
Systemic hypoxia differentially affects neurogenesis during early mouse brain maturation.
Brain & development 2012;34(4):261-73.
2012: Max Gassmann; Omolara O Ogunshola; Martha Tissot van Patot
The impact of hypoxia on cells, mice, and men.
High altitude medicine & biology 2012;13(1):63-4.
2011: Junmin Hu; Hubert Rehrauer; Claudia Setzer; Dheeraj A Shinde; Daniel Stiehl; Daniela Wichmann; Max Gassmann; Pavel Hradecky; Thomas A Gorr
Interaction of HIF and USF signaling pathways in human genes flanked by hypoxia-response elements and E-box palindromes.
Molecular cancer research : MCR 2011;9(11):1520-36.
2011: Milena Segato Komniski; Sergej Yakushev; Nikolai Bogdanov; Max Gassmann; Anna Bogdanova
Interventricular heterogeneity in rat heart responses to hypoxia: the tuning of glucose metabolism, ion gradients, and function.
American journal of physiology. Heart and circulatory physiology 2011;300(5):H1645-52.
2011: Xanthi Antoniou; Max Gassmann; Omolara O Ogunshola
Cdk5 interacts with Hif-1α in neurons: a new hypoxic signalling mechanism?
Brain research 2011;1381():1-10.
2011: Johannes Vogel; Max Gassmann
Erythropoietic and non-erythropoietic functions of erythropoietin in mouse models.
The Journal of physiology 2011;589(Pt 6):1259-64.
2011: Abraham Al Ahmad; Carole Bürgi Taboada; Max Gassmann; Omolara O Ogunshola
Astrocytes and pericytes differentially modulate blood-brain barrier characteristics during development and hypoxic insult.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(2):693-705.
2011: Max Gassmann
Oxygen 2011.
High altitude medicine & biology 2011;12(2):187-8.
2011: Martha C Tissot van Patot; Max Gassmann
Hypoxia: adapting to high altitude by mutating EPAS-1, the gene encoding HIF-2α.
High altitude medicine & biology 2011;12(2):157-67.
2010: Regina Trollmann; Hubert Rehrauer; Christina Schneider; Gudrun Krischke; Nicolas Huemmler; Stephan Keller; Wolfgang Rascher; Max Gassmann
Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain.
American journal of physiology. Regulatory, integrative and comparative physiology 2010;299(6):R1489-99.
2010: Thomas A Gorr; D Wichmann; J Hu; M Hermes-Lima; A F Welker; N Terwilliger; J F Wren; M Viney; S Morris; G E Nilsson; Alexander Deten; Jorge Soliz; Max Gassmann
Hypoxia tolerance in animals: biology and application.
Physiological and biochemical zoology : PBZ 2010;83(5):733-52.
2010: Asya Makhro; Jue Wang; Johannes Vogel; Alexander A Boldyrev; Max Gassmann; Lars Kaestner; Anna Bogdanova
Functional NMDA receptors in rat erythrocytes.
American journal of physiology. Cell physiology 2010;298(6):C1315-25.
2010: Anna Bogdanova; Ilmar Heinicke; Max Gassmann; Katja Heinicke
Oxygen-induced regulation of the intracellular glutathione levels in erythrocytes.
European journal of applied physiology 2010;109(3):575-6.
2010: Beat Schuler; Margarete Arras; Stephan Keller; Andreas Rettich; Carsten Lundby; Johannes Vogel; Max Gassmann
Optimal hematocrit for maximal exercise performance in acute and chronic erythropoietin-treated mice.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):419-23.
2009: Arianne Monge Naldi; Max Gassmann; Daniel Bodmer
Erythropoietin but not VEGF has a protective effect on auditory hair cells in the inner ear.
Cellular and molecular life sciences : CMLS 2009;66(22):3595-9.
2009: Max Gassmann; Jorge Soliz
Erythropoietin modulates the neural control of hypoxic ventilation.
Cellular and molecular life sciences : CMLS 2009;66(22):3575-82.
2009: Max Gassmann
The impact of hypoxia on our body: from integrative physiology to human disease.
Cellular and molecular life sciences : CMLS 2009;66(22):3537-8.
2009: Max Gassmann; Martha Tissot van Patot; Jorge Soliz
The neuronal control of hypoxic ventilation: erythropoietin and sexual dimorphism.
Annals of the New York Academy of Sciences 2009;1177():151-61.
2009: Deyan Mihov; Johannes Vogel; Max Gassmann; Anna Bogdanova
Erythropoietin activates nitric oxide synthase in murine erythrocytes.
American journal of physiology. Cell physiology 2009;297(2):C378-88.
2009: Ilmar Heinicke; Annette Boehler; Thomas Rechsteiner; Anna Bogdanova; Wolfgang Jelkmann; Markus Hofer; Pablo Rawlings; Oscar Araneda; Claus Behn; Max Gassmann; Katja Heinicke
Moderate altitude but not additional endurance training increases markers of oxidative stress in exhaled breath condensate.
European journal of applied physiology 2009;106(4):599-604.
2009: Max Gassmann; Beat Grenacher; Bianca Rohde; Johannes Vogel
Quantifying Western blots: pitfalls of densitometry.
Electrophoresis 2009;30(11):1845-55.
2009: Jorge Soliz; Jonas Juhl Thomsen; Christophe Soulage; Carsten Lundby; Max Gassmann
Sex-dependent regulation of hypoxic ventilation in mice and humans is mediated by erythropoietin.
American journal of physiology. Regulatory, integrative and comparative physiology 2009;296(6):R1837-46.
2009: Abraham Al Ahmad; Max Gassmann; Omolara O Ogunshola
Maintaining blood-brain barrier integrity: pericytes perform better than astrocytes during prolonged oxygen deprivation.
Journal of cellular physiology 2009;218(3):612-22.
2009: Beat Schuler; Andreas Rettich; Johannes Vogel; Max Gassmann; Margarete Arras
Optimized surgical techniques and postoperative care improve survival rates and permit accurate telemetric recording in exercising mice.
BMC veterinary research 2009;5():28.
2008: Regina Trollmann; Katja Strasser; Stephan Keller; Xenia Antoniou; Beat Grenacher; Omolara O Ogunshola; Jörg Dötsch; Wolfgang Rascher; Max Gassmann
Placental HIFs as markers of cerebral hypoxic distress in fetal mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(6):R1973-81.
2008: Nicole Schmid-Brunclik; Carole Bürgi Tabaoada; Xanthi Antoniou; Max Gassmann; Omolara O Ogunshola
Astrocyte responses to injury: VEGF simultaneously modulates cell death and proliferation.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(3):R864-73.
2008: Jorge Soliz; Christophe Soulage; Emanuela Borter; Martha Tissot van Patot; Max Gassmann
Ventilatory responses to acute and chronic hypoxia are altered in female but not male Paskin-deficient mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(2):R649-58.
2008: Max Gassmann; Annamaria Manini; Thomas Stallmach; Bianca Saam; Gisela Kuhn; Beat Grenacher; Anna Bogdanova; Johannes Vogel
Abortion in mice with excessive erythrocytosis is due to impaired arteriogenesis of the uterine arcade.
Biology of reproduction 2008;78(6):1049-57.
2008: Regina Trollmann; Julia Schneider; Stephan Keller; Katja Strasser; Dieter Wenzel; Wolfgang Rascher; Omolara O Ogunshola; Max Gassmann
HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam.
Brain research 2008;1199():27-36.
2008: Michael Elser; Lubor Borsig; Paul O Hassa; Suheda Erener; Simon Messner; Taras Valovka; Stephan Keller; Max Gassmann; Michael Hottiger
Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expression.
Molecular cancer research : MCR 2008;6(2):282-90.
2007: Irina Yu Petrushanko; Nikolai B Bogdanov; N Lapina; Alexander A Boldyrev; Max Gassmann; Anna Bogdanova
Oxygen-induced Regulation of Na/K ATPase in cerebellar granule cells.
The Journal of general physiology 2007;130(4):389-98.
2007: Jorge Soliz; Christophe Soulage; Dirk M Hermann; Max Gassmann
Acute and chronic exposure to hypoxia alters ventilatory pattern but not minute ventilation of mice overexpressing erythropoietin.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(4):R1702-10.
2007: Jorge Soliz; Max Gassmann; Vincent Joseph
Soluble erythropoietin receptor is present in the mouse brain and is required for the ventilatory acclimatization to hypoxia.
The Journal of physiology 2007;583(Pt 1):329-36.
2007: Anna Bogdanova; Deyan Mihov; Hans Lutz; Bianca Saam; Max Gassmann; Johannes Vogel
Enhanced erythro-phagocytosis in polycythemic mice overexpressing erythropoietin.
Blood 2007;110(2):762-9.
2007: Natalie Inteeworn; Stefanie Ohlerth; Gisele Höpfl; Franco Guscetti; Carla Rohrer Bley; Melanie Wergin; Malgorzata Roos; Max Gassmann; Barbara Kaser-Hotz
Simultaneous application of the vascular endothelial growth factor (VEGF) receptor inhibitor PTK787/ZK 222584 and ionizing radiation does not further reduce the growth of canine oral melanoma xenografts in nude mice.
Veterinary journal (London, England : 1997) 2007;173(3):564-70.
2007: Giovanni G Camici; Thomas Stallmach; Matthias Hermann; Rutger J Hassink; Peter Doevendans; Beat Grenacher; Alain Hirschy; Johannes Vogel; Thomas F Lüscher; Frank Ruschitzka; Max Gassmann
Constitutively overexpressed erythropoietin reduces infarct size in a mouse model of permanent coronary artery ligation.
Methods in enzymology 2007;435():147-55.
2006: Katja Heinicke; Oliver Baum; Omolara O Ogunshola; Johannes Vogel; Thomas Stallmach; David P Wolfer; Stephan Keller; Klaus Weber; Peter D Wagner; Max Gassmann; Valentin Djonov
Excessive erythrocytosis in adult mice overexpressing erythropoietin leads to hepatic, renal, neuronal, and muscular degeneration.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(4):R947-56.
2006: Thomas A Gorr; Max Gassmann; Pablo Wappner
Sensing and responding to hypoxia via HIF in model invertebrates.
Journal of insect physiology 2006;52(4):349-64.
2006: I Petrushanko; N Bogdanov; Elena Bulygina; Beat Grenacher; T Leinsoo; Alexander Boldyrev; Max Gassmann; Anna Bogdanova
Na-K-ATPase in rat cerebellar granule cells is redox sensitive.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(4):R916-25.
2006: Bernadette Ateghang; Maria Wartenberg; Max Gassmann; Heinrich Sauer
Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species.
Journal of cell science 2006;119(Pt 6):1043-52.
2006: Omolara O Ogunshola; Valentin Djonov; R Staudt; Johannes Vogel; Max Gassmann
Chronic excessive erythrocytosis induces endothelial activation and damage in mouse brain.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(3):R678-84.
2006: Leonhard Schäffer; Johannes Vogel; Christian Breymann; Max Gassmann; Hugo H Marti
Preserved placental oxygenation and development during severe systemic hypoxia.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(3):R844-51.
2006: Arianne Monge; Ivana Nagy; Sharouz Bonabi; Stephan Schmid; Max Gassmann; Daniel Bodmer
The effect of erythropoietin on gentamicin-induced auditory hair cell loss.
The Laryngoscope 2006;116(2):312-6.
2005: Ertugrul Kilic; Ulkan Kilic; Jorge Soliz; Claudio Bassetti; Max Gassmann; Dirk M Hermann
Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):2026-8.
2005: Jorge Soliz; Vincent Joseph; Christophe Soulage; Csilla Becskei; Johannes Vogel; Jean-Marc Pequignot; Omolara O Ogunshola; Max Gassmann
Erythropoietin regulates hypoxic ventilation in mice by interacting with brainstem and carotid bodies.
The Journal of physiology 2005;568(Pt 2):559-71.
2005: Katrin Wassel; Gisela Kuhn; Max Gassmann; Johannes Vogel
Permanently increased conductance of the murine uterine arcade after the first pregnancy.
European journal of morphology 2005;42(4-5):225-32.
2005: Norbert Weissmann; Daniel Manz; Daniela Buchspies; Stephan Keller; Tanja Mehling; Robert Voswinckel; Karin Quanz; Hossein A Ghofrani; Ralph Theo Schermuly; Ludger Fink; Werner Seeger; Max Gassmann; Friedrich Grimminger
Congenital erythropoietin over-expression causes "anti-pulmonary hypertensive" structural and functional changes in mice, both in normoxia and hypoxia.
Thrombosis and haemostasis 2005;94(3):630-8.
2005: Mirjam Cramer; Ivana Nagy; Brian J Murphy; Max Gassmann; Michael Hottiger; Oleg Georgiev; Walter Schaffner
NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells.
Biological chemistry 2005;386(9):865-72.
2005: Anna Bogdanova; Beat Grenacher; Mikko Nikinmaa; Max Gassmann
Hypoxic responses of Na+/K+ ATPase in trout hepatocytes.
The Journal of experimental biology 2005;208(Pt 10):1793-801.
2005: Ulkan Kilic; Ertugrul Kilic; Jorge Soliz; Claudio Bassetti; Max Gassmann; Dirk M Hermann
Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(2):249-51.
2005: Mauro Giuliani; Wolfgang Moritz; Elvira Bodmer; Daniel Dindo; Patrick Kugelmeier; Roger Lehmann; Max Gassmann; Peter Groscurth; Markus Weber
Central necrosis in isolated hypoxic human pancreatic islets: evidence for postisolation ischemia.
Cell transplantation 2005;14(1):67-76.
2004: Oliver Distler; Jörg H W Distler; Annette Scheid; Till Acker; Astrid Hirth; Janine Rethage; Beat A Michel; Renate E Gay; Ulf Müller-Ladner; Marco Matucci-Cerinic; Karl H Plate; Max Gassmann; Steffen Gay
Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis.
Circulation research 2004;95(1):109-16.
2004: Tony M Glaus; Beat Grenacher; Daniel Koch; Barbel Reiner; Max Gassmann
High altitude training of dogs results in elevated erythropoietin and endothelin-1 serum levels.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2004;138(3):355-61.
2004: Roger Achermann; Stefanie Ohlerth; Carla Rohrer Bley; Max Gassmann; Natalie Inteeworn; Malgorzata Roos; Myriam Schärz; Melanie Wergin; Barbara Kaser-Hotz
Oxygenation of spontaneous canine tumors during fractionated radiation therapy.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2004;180(5):297-305.
2004: Gisele Höpfl; Omolara O Ogunshola; Max Gassmann
HIFs and tumors--causes and consequences.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;286(4):R608-23.
2004: Thomas Hofer; Raimo Pohjanvirta; Patrick Spielmann; Matti Viluksela; David P Buchmann; Roland H Wenger; Max Gassmann
Simultaneous exposure of rats to dioxin and carbon monoxide reduces the xenobiotic but not the hypoxic response.
Biological chemistry 2004;385(3-4):291-4.
2004: Gisele Höpfl; Max Gassmann; Isabelle Desbaillets
Differentiating embryonic stem cells into embryoid bodies.
Methods in molecular biology (Clifton, N.J.) 2004;254():79-98.
2004: Jörg H W Distler; Roland H Wenger; Max Gassmann; Mariola Kurowska; Astrid Hirth; Steffen Gay; Oliver Distler
Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis.
Arthritis and rheumatism 2004;50(1):10-23.
2003: Leonhard Schäffer; Annette Scheid; Patrick Spielmann; Christian Breymann; Roland Zimmermann; Martin Meuli; Max Gassmann; Hugo H Marti; Roland H Wenger
Oxygen-regulated expression of TGF-beta 3, a growth factor involved in trophoblast differentiation.
Placenta 2003;24(10):941-50.
2003: Jeanne-Françoise Roth; Noriko Shikama; Clea Henzen; Isabelle Desbaillets; Werner Lutz; Silvia Marino; Jonas Wittwer; Hubert Schorle; Max Gassmann; Richard Eckner
Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5.
The EMBO journal 2003;22(19):5186-96.
2003: Dörthe M Katschinski; Hugo H Marti; Klaus F Wagner; Junpei Shibata; Katrin Eckhardt; Falk Martin; Reinhard Depping; Uwe Paasch; Max Gassmann; Birgit Ledermann; Isabelle Desbaillets; Roland H Wenger
Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN.
Molecular and cellular biology 2003;23(19):6780-9.
2003: Johannes Vogel; Isabel Kiessling; Katja Heinicke; Thomas Stallmach; Pete Ossent; Olga Vogel; Michael Aulmann; Thomas Frietsch; Holger Schmid-Schönbein; Wolfgang Kuschinsky; Max Gassmann
Transgenic mice overexpressing erythropoietin adapt to excessive erythrocytosis by regulating blood viscosity.
Blood 2003;102(6):2278-84.
2003: Anna Bogdanova; Omolara O Ogunshola; Christian Bauer; Max Gassmann
Pivotal role of reduced glutathione in oxygen-induced regulation of the Na(+)/K(+) pump in mouse erythrocyte membranes.
The Journal of membrane biology 2003;195(1):33-42.
2003: Junpei Shibata; Jo Hasegawa; Hans-Joachim G Siemens; Eva-Maria Wolber; Leif Dibbelt; Dechun Li; Dörthe M Katschinski; Joachim Fandrey; Wolfgang Jelkmann; Max Gassmann; Roland H Wenger; Klaus F Wagner
Hemostasis and coagulation at a hematocrit level of 0.85: functional consequences of erythrocytosis.
Blood 2003;101(11):4416-22.
2003: Thomas Quaschning; Frank Ruschitzka; Thomas Stallmach; Sidney Shaw; Henning Morawietz; Winfried Goettsch; Matthias Hermann; Torsten Slowinski; Franz Theuring; Berthold Hocher; Thomas F Lüscher; Max Gassmann
Erythropoietin-induced excessive erythrocytosis activates the tissue endothelin system in mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(2):259-61.
2003: Max Gassmann; Katja Heinicke; Jorge Soliz; Omolara O Ogunshola
Non-erythroid functions of erythropoietin.
Advances in experimental medicine and biology 2003;543():323-30.
2003: Gisele Höpfl; Omolara O Ogunshola; Max Gassmann
Hypoxia and high altitude. The molecular response.
Advances in experimental medicine and biology 2003;543():89-115.
2003: Anna Bogdanova; Omolara O Ogunshola; Christian Bauer; Mikko Nikinmaa; Max Gassmann
Molecular mechanisms of oxygen-induced regulation of Na+/K+ pump.
Advances in experimental medicine and biology 2003;536():231-8.
2003: Thomas Hofer; Roland H Wenger; Marianne F Kramer; Gloria C Ferreira; Max Gassmann
Hypoxic up-regulation of erythroid 5-aminolevulinate synthase.
Blood 2003;101(1):348-50.
2002: Thomas Hofer; Isabelle Desbaillets; Gisele Höpfl; Roland H Wenger; Max Gassmann
Characterization of HIF-1 alpha overexpressing HeLa cells and implications for gene therapy.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2002;133(4):475-81.
2002: Roger Achermann; Stefanie Ohlerth; Janean L Fidel; Olivier Gardelle; Max Gassmann; Malgorzata Roos; H Mark Saunders; Annette Scheid; Melanie Wergin; Barbara Kaser-Hotz
Ultrasound guided, pre-radiation oxygen measurements using polarographic oxygen needle electrodes in spontaneous canine soft tissue sarcomas.
In vivo (Athens, Greece) 2002;16(6):431-7.
2002: Frank Rose; Friedrich Grimminger; Jutta Appel; Mathias Heller; Volker Pies; Norbert Weissmann; Ludger Fink; Sebastian Schmidt; Stefanie Krick; Gieri Camenisch; Max Gassmann; Werner Seeger; Jörg Hänze
Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(12):1660-1.
2002: Torsten Slowinski; Norma Schulz; Frank Ruschitzka; Thomas Quaschning; Christian Bauer; Franz Theuring; Hans-Hellmut Neumayer; Max Gassmann; Berthold Hocher
Pattern of prepro-endothelin-1 expression revealed by reporter-gene activity in kidneys of erythropoietin-overexpressing mice.
Clinical science (London, England : 1979) 2002;103 Suppl 48():44S-47S.
2002: Gisele Höpfl; Roland H Wenger; Urs Ziegler; Thomas Stallmach; Olivier Gardelle; Roger Achermann; Melanie Wergin; Barbara Kaser-Hotz; H Mark Saunders; Kaye J Williams; Ian J Stratford; Max Gassmann; Isabelle Desbaillets
Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor.
Cancer research 2002;62(10):2962-70.
2002: Wolfgang Moritz; Franziska Meier; Deborah Stroka; Mauro Giuliani; Patrick Kugelmeier; Philipp C Nett; Roger Lehmann; Daniel Candinas; Max Gassmann; Markus Weber
Apoptosis in hypoxic human pancreatic islets correlates with HIF-1alpha expression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):745-7.
2002: M Tini; U R Jewell; Gieri Camenisch; D Chilov; Max Gassmann
Generation and application of chicken egg-yolk antibodies.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2002;131(3):569-74.
2002: Annette Scheid; Roland H Wenger; Leonhard Schäffer; Isabelle Camenisch; Oliver Distler; Andrej Ferenc; Heidi Cristina; Heather E Ryan; Randall S Johnson; Klaus F Wagner; Urs G Stauffer; Christian Bauer; Max Gassmann; Martin Meuli
Physiologically low oxygen concentrations in fetal skin regulate hypoxia-inducible factor 1 and transforming growth factor-beta3.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(3):411-3.
2002: Thomas Hofer; H Wenger; Max Gassmann
Oxygen sensing, HIF-1alpha stabilization and potential therapeutic strategies.
Pflügers Archiv : European journal of physiology 2002;443(4):503-7.
2002: Anna Bogdanova; Max Gassmann; Mikko Nikinmaa
Copper ion redox state is critical for its effects on ion transport pathways and methaemoglobin formation in trout erythrocytes.
Chemico-biological interactions 2002;139(1):43-59.
2002: Gieri Camenisch; Roland H Wenger; Max Gassmann
DNA-binding activity of hypoxia-inducible factors (HIFs).
Methods in molecular biology (Clifton, N.J.) 2002;196():117-29.
2001: D Chilov; Thomas Hofer; Christian Bauer; Roland H Wenger; Max Gassmann
Hypoxia affects expression of circadian genes PER1 and CLOCK in mouse brain.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2613-22.
2001: Thomas Hofer; Isabelle Desbaillets; Gisele Höpfl; Max Gassmann; Roland H Wenger
Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2715-7.
2001: Thomas Hofer; Patrick Spielmann; P Stengel; B Stier; Dörthe M Katschinski; Isabelle Desbaillets; Max Gassmann; Roland H Wenger
Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors.
Biochemical and biophysical research communications 2001;288(4):757-64.
2001: Gieri Camenisch; Deborah Stroka; Max Gassmann; Roland H Wenger
Attenuation of HIF-1 DNA-binding activity limits hypoxia-inducible endothelin-1 expression.
Pflügers Archiv : European journal of physiology 2001;443(2):240-9.
2001: Deborah Stroka; T Burkhardt; Isabelle Desbaillets; Roland H Wenger; Desley A H Neil; Christian Bauer; Max Gassmann; Daniel Candinas
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2445-53.
2001: Max Gassmann
[Oxygen deficiency and erythropoietin].
Schweizer Archiv für Tierheilkunde 2001;143(9):455-60.
2001: Arto Soitamo; C M Rabergh; Max Gassmann; Lea Sistonen; Mikko Nikinmaa
Characterization of a hypoxia-inducible factor (HIF-1alpha ) from rainbow trout. Accumulation of protein occurs at normal venous oxygen tension.
The Journal of biological chemistry 2001;276(23):19699-705.
2001: U R Jewell; I Kvietikova; Annette Scheid; Christian Bauer; Roland H Wenger; Max Gassmann
Induction of HIF-1alpha in response to hypoxia is instantaneous.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(7):1312-4.
2001: Klaus F Wagner; Dörthe M Katschinski; Jo Hasegawa; D Schumacher; Birgit Meller; Ulrich Gembruch; Uda Schramm; Wolfgang Jelkmann; Max Gassmann; Joachim Fandrey
Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin.
Blood 2001;97(2):536-42.
2000: Annette Scheid; Martin Meuli; Max Gassmann; Roland H Wenger
Genetically modified mouse models in studies on cutaneous wound healing.
Experimental physiology 2000;85(6):687-704.
2000: Isabelle Desbaillets; Urs Ziegler; Peter Groscurth; Max Gassmann
Embryoid bodies: an in vitro model of mouse embryogenesis.
Experimental physiology 2000;85(6):645-51.
2000: A Görlach; Gieri Camenisch; I Kvietikova; L Vogt; Roland H Wenger; Max Gassmann
Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions.
Biochimica et biophysica acta 2000;1493(1-2):125-34.
2000: R M Wanner; Patrick Spielmann; Deborah Stroka; Gieri Camenisch; Isabelle Camenisch; Annette Scheid; D R Houck; Christian Bauer; Max Gassmann; Roland H Wenger
Epolones induce erythropoietin expression via hypoxia-inducible factor-1 alpha activation.
Blood 2000;96(4):1558-65.
2000: Vojtech Pavlicek; Hugo H Marti; Sibylle Grad; J Simon R Gibbs; C Kol; Roland H Wenger; Max Gassmann; Jana Kohl; FE Maly; Oswald Oelz; Erwin A Koller; Christian Schirlo
Effects of hypobaric hypoxia on vascular endothelial growth factor and the acute phase response in subjects who are susceptible to high-altitude pulmonary oedema.
European journal of applied physiology 2000;81(6):497-503.
2000: Annette Scheid; Roland H Wenger; H Christina; Isabelle Camenisch; A Ferenc; Urs G Stauffer; Max Gassmann; Martin Meuli
Hypoxia-regulated gene expression in fetal wound regeneration and adult wound repair.
Pediatric surgery international 2000;16(4):232-6.
2000: Max Gassmann; D Chilov; Roland H Wenger
Regulation of the hypoxia-inducible factor-1 alpha. ARNT is not necessary for hypoxic induction of HIF-1 alpha in the nucleus.
Advances in experimental medicine and biology 2000;475():87-99.
1999: R Assandri; M Egger; Max Gassmann; Ernst Niggli; C Bauer; Ian Forster; A Gorlach
Erythropoietin modulates intracellular calcium in a human neuroblastoma cell line.
The Journal of physiology 1999;516 ( Pt 2)():343-52.
1999: D Chilov; Gieri Camenisch; I Kvietikova; Urs Ziegler; Max Gassmann; Roland H Wenger
Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1alpha.
Journal of cell science 1999;112 ( Pt 8)():1203-12.
1999: S Bichet; Roland H Wenger; Gieri Camenisch; A Rolfs; W Ehleben; T Porwol; Helmut Acker; Joachim Fandrey; Christian Bauer; Max Gassmann
Oxygen tension modulates beta-globin switching in embryoid bodies.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(2):285-95.
1999: Gieri Camenisch; M Tini; D Chilov; I Kvietikova; Vickram Srinivas; Jaime Caro; Patrick Spielmann; Roland H Wenger; Max Gassmann
General applicability of chicken egg yolk antibodies: the performance of IgY immunoglobulins raised against the hypoxia-inducible factor 1alpha.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(1):81-8.
1998: Roland H Wenger; Gieri Camenisch; Isabelle Desbaillets; D Chilov; Max Gassmann
Up-regulation of hypoxia-inducible factor-1alpha is not sufficient for hypoxic/anoxic p53 induction.
Cancer research 1998;58(24):5678-80.
1998: Roland H Wenger; Hugo H Marti; C Bauer; Max Gassmann
Optimal erythropoietin expression in human hepatoma cell lines requires activation of multiple signalling pathways.
International journal of molecular medicine 1998;2(3):317-24.
1998: Roland H Wenger; I Kvietikova; A Rolfs; Gieri Camenisch; Max Gassmann
Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site.
European journal of biochemistry / FEBS 1998;253(3):771-7.
1998: Roland H Wenger; A Rolfs; Patrick Spielmann; D R Zimmermann; Max Gassmann
Mouse hypoxia-inducible factor-1alpha is encoded by two different mRNA isoforms: expression from a tissue-specific and a housekeeping-type promoter.
Blood 1998;91(9):3471-80.
1998: Max Gassmann; Thierry Hennet; C Bauer
[Transgenic mice in basic research].
Schweizer Archiv für Tierheilkunde 1998;140(5):198-204.
1997: A Rolfs; I Kvietikova; Max Gassmann; Roland H Wenger
Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1.
The Journal of biological chemistry 1997;272(32):20055-62.
1997: Roland H Wenger; Max Gassmann
Oxygen(es) and the hypoxia-inducible factor-1.
Biological chemistry 1997;378(7):609-16.
1997: Roland H Wenger; A Rolfs; I Kvietikova; Patrick Spielmann; D R Zimmermann; Max Gassmann
The mouse gene for hypoxia-inducible factor-1alpha--genomic organization, expression and characterization of an alternative first exon and 5' flanking sequence.
European journal of biochemistry / FEBS 1997;246(1):155-65.
1997: Max Gassmann; I Kvietikova; A Rolfs; Roland H Wenger
Oxygen- and dioxin-regulated gene expression in mouse hepatoma cells.
Kidney international 1997;51(2):567-74.
1997: I Kvietikova; Roland H Wenger; Hugo H Marti; Max Gassmann
The hypoxia-inducible factor-1 DNA recognition site is cAMP-responsive.
Kidney international 1997;51(2):564-6.
1997: Roland H Wenger; I Kvietikova; A Rolfs; Max Gassmann; Hugo H Marti
Hypoxia-inducible factor-1 alpha is regulated at the post-mRNA level.
Kidney international 1997;51(2):560-3.
1997: Hugo H Marti; Max Gassmann; Roland H Wenger; I Kvietikova; Maria Cristina Morganti-Kossmann; Thomas Kossmann; O Trentz; Christian Bauer
Detection of erythropoietin in human liquor: intrinsic erythropoietin production in the brain.
Kidney international 1997;51(2):416-8.
1996: Gieri Camenisch; M Gruber; G Donoho; P Van Sloun; Roland H Wenger; Max Gassmann
A polyoma-based episomal vector efficiently expresses exogenous genes in mouse embryonic stem cells.
Nucleic acids research 1996;24(19):3707-13.
1996: Katarina Gradin; Jacqueline McGuire; Roland H Wenger; I Kvietikova; M L fhitelaw; Rune Toftgård; L Tora; Max Gassmann; Lorenz Poellinger
Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor.
Molecular and cellular biology 1996;16(10):5221-31.
1996: Roland H Wenger; A Rolfs; Hugo H Marti; J L Guénet; Max Gassmann
Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha.
Biochemical and biophysical research communications 1996;223(1):54-9.
1996: Max Gassmann; Joachim Fandrey; S Bichet; Maria Wartenberg; Hugo H Marti; Christian Bauer; Roland H Wenger; Helmut Acker
Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2867-72.
1996: Hugo H Marti; Roland H Wenger; L A Rivas; U Straumann; Murat Digicaylioglu; V Henn; Y Yonekawa; Christian Bauer; Max Gassmann
Erythropoietin gene expression in human, monkey and murine brain.
The European journal of neuroscience 1996;8(4):666-76.
1996: Roland H Wenger; Hugo H Marti; C C Schuerer-Maly; I Kvietikova; Christian Bauer; Max Gassmann; F E Maly
Hypoxic induction of gene expression in chronic granulomatous disease-derived B-cell lines: oxygen sensing is independent of the cytochrome b558-containing nicotinamide adenine dinucleotide phosphate oxidase.
Blood 1996;87(2):756-61.
1995: I Kvietikova; Roland H Wenger; Hugo H Marti; Max Gassmann
The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site.
Nucleic acids research 1995;23(22):4542-50.
1995: Roland H Wenger; A Rolfs; Hugo H Marti; Christian Bauer; Max Gassmann
Hypoxia, a novel inducer of acute phase gene expression in a human hepatoma cell line.
The Journal of biological chemistry 1995;270(46):27865-70.
1995: Max Gassmann; Maria Wartenberg; T McClanahan; J Fandrey; S Bichet; R Kreuter; H Acker; C Bauer
Differentiating embryonic stem cells as an in vitro model of early erythropoiesis.
Toxicology in vitro : an international journal published in association with BIBRA 1995;9(4):429-38.
1995: Murat Digicaylioglu; S Bichet; Hugo H Marti; Roland H Wenger; L A Rivas; Christian Bauer; Max Gassmann
Localization of specific erythropoietin binding sites in defined areas of the mouse brain.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(9):3717-20.
1995: Max Gassmann; G Donoho; Paul Berg
Maintenance of an extrachromosomal plasmid vector in mouse embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1292-6.
1991: T Weiser; Max Gassmann; P Thömmes; E Ferrari; P Hafkemeyer; Ulrich Hübscher
Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus.
The Journal of biological chemistry 1991;266(16):10420-8.
1990: Max Gassmann; P Thömmes; T Weiser; Ulrich Hübscher
Efficient production of chicken egg yolk antibodies against a conserved mammalian protein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(8):2528-32.
1990: Max Gassmann; T Weiser; P Thömmes; Ulrich Hübscher
[The chicken egg as a supply of polyclonal antibodies].
Schweizer Archiv für Tierheilkunde 1990;132(6):289-94.
1989: F Focher; Max Gassmann; P Hafkemeyer; E Ferrari; S Spadari; Ulrich Hübscher
Calf thymus DNA polymerase delta independent of proliferating cell nuclear antigen (PCNA).
Nucleic acids research 1989;17(5):1805-21.
1988: Max Gassmann; F Focher; H J Buhk; E Ferrari; S Spadari; Ulrich Hübscher
Replication of single-stranded porcine circovirus DNA by DNA polymerases alpha and delta.
Biochimica et biophysica acta 1988;951(2-3):280-9.
1988: R A Hammond; K A Foster; M W Berchthold; Max Gassmann; A M Holmes; U Hübscher; Neal C Brown
Calcium-dependent calmodulin-binding proteins associated with mammalian DNA polymerase alpha.
Biochimica et biophysica acta 1988;951(2-3):315-21.
1988: F Focher; S Spadari; B Ginelli; M Hottiger; Max Gassmann; Ulrich Hübscher
Calf thymus DNA polymerase delta: purification, biochemical and functional properties of the enzyme after its separation from DNA polymerase alpha, a DNA dependent ATPase and proliferating cell nuclear antigen.
Nucleic acids research 1988;16(14A):6279-95.
1987: Ulrich Hübscher; Max Gassmann; S Spadari; Neal C Brown; E Ferrari; H J Buhk
Mammalian DNA polymerase alpha: a replication-competent holoenzyme form from calf thymus.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1987;317(1187):421-8.