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John Gatley

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Meghan Johnston; Alexandros Makriyannis; Richard W Mercier; Surina Sikka; Jay M West; Shachi R Bhatt; S John Gatley; Richard I Duclos
Assay and inhibition of diacylglycerol lipase activity.
Richard I Duclos; Meghan Johnston; Subramanian K Vadivel; Alexandros Makriyannis; Sherrye T Glaser; S John Gatley
A methodology for radiolabeling of the endocannabinoid 2-arachidonoylglycerol (2-AG).
Onarae V Rice; Alicia V Grande; Natasha Dehktyar; Magalie Bruneus; John K Robinson; S John Gatley
Long-term effects of irradiation with iron-56 particles on the nigrostriatal dopamine system.

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2012: Meghan Johnston; Alexandros Makriyannis; Richard W Mercier; Surina Sikka; Jay M West; Shachi R Bhatt; S John Gatley; Richard I Duclos
Assay and inhibition of diacylglycerol lipase activity.
Bioorganic & medicinal chemistry letters 2012;22(14):4585-92.
2011: Richard I Duclos; Meghan Johnston; Subramanian K Vadivel; Alexandros Makriyannis; Sherrye T Glaser; S John Gatley
A methodology for radiolabeling of the endocannabinoid 2-arachidonoylglycerol (2-AG).
The Journal of organic chemistry 2011;76(7):2049-55.
2009: Onarae V Rice; Alicia V Grande; Natasha Dehktyar; Magalie Bruneus; John K Robinson; S John Gatley
Long-term effects of irradiation with iron-56 particles on the nigrostriatal dopamine system.
Radiation and environmental biophysics 2009;48(2):215-25.
2008: Andrew N Gifford; Mel Pilar Espaillat; S John Gatley
Biodistribution of radiolabeled ethanol in rodents.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(9):1853-8.
2006: Kimberly P Lindsey; S John Gatley
Applications of clinical dopamine imaging.
Neuroimaging clinics of North America 2006;16(4):553-73, vii-viii.
2006: Jasbeer Dhawan; Hongfeng Deng; S John Gatley; Alexandros Makriyannis; Tolulope Akinfeleye; Magalie Bruneus; Alexis A Dimaio; Andrew N Gifford
Evaluation of the in vivo receptor occupancy for the behavioral effects of cannabinoids using a radiolabeled cannabinoid receptor agonist, R-[125/131I]AM2233.
Synapse (New York, N.Y.) 2006;60(2):93-101.
2006: Sherrye T Glaser; S John Gatley; Andrew N Gifford
Ex vivo imaging of fatty acid amide hydrolase activity and its inhibition in the mouse brain.
The Journal of pharmacology and experimental therapeutics 2006;316(3):1088-97.
2006: Onarae Rice; Sandra Saintvictor; Michael Michaelides; Panayotis Thanos; S John Gatley
MicroPET investigation of chronic long-term neurotoxicity from heavy ion irradiation.
The AAPS journal 2006;8(3):E508-14.
2006: Nora D Volkow; Gene-Jack Wang; Dinko Franceschi; Joanna S Fowler; Panayotis Peter K Thanos; Laurence Maynard; S John Gatley; Christopher Wong; Richard L Veech; George Kunos; Ting Kai Li
Low doses of alcohol substantially decrease glucose metabolism in the human brain.
NeuroImage 2006;29(1):295-301.
2005: Hongfeng Deng; Andrew N Gifford; Alexander M Zvonok; Guangjian Cui; Xiuyan Li; Pusheng Fan; Jeffrey Deschamps; Judith L Flippen-Anderson; S John Gatley; Alexandros Makriyannis
Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.
Journal of medicinal chemistry 2005;48(20):6386-92.
2005: Zizhong Li; Andrew Gifford; Qian Liu; Rajesh Thotapally; Yu-Shin Ding; Alexandros Makriyannis; S John Gatley
Candidate PET radioligands for cannabinoid CB1 receptors: [18F]AM5144 and related pyrazole compounds.
Nuclear medicine and biology 2005;32(4):361-6.
2005: K P Lindsey; Sherrye T Glaser; S John Gatley
Imaging of the brain cannabinoid system.
Handbook of experimental pharmacology 2005;(168):425-43.
2005: S John Gatley; Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; Yu-Shin Ding; Madina R Gerasimov
PET imaging in clinical drug abuse research.
Current pharmaceutical design 2005;11(25):3203-19.
2004: Yu-Shin Ding; S John Gatley; Panayotis K Thanos; Colleen Shea; Victor Garza; Youwen Xu; Pauline Carter; Payton King; Donald Warner; Nicholas B Taintor; Daniel J Park; Bea Pyatt; Joanna S Fowler; Nora D Volkow
Brain kinetics of methylphenidate (Ritalin) enantiomers after oral administration.
Synapse (New York, N.Y.) 2004;53(3):168-75.
2004: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Frank Telang; Laurence Maynard; Jean Logan; S John Gatley; Naomi Pappas; Christopher Wong; Paul Vaska; Wei Zhu; James M Swanson
Evidence that methylphenidate enhances the saliency of a mathematical task by increasing dopamine in the human brain.
The American journal of psychiatry 2004;161(7):1173-80.
2004: Panayotis K Thanos; Nicholas B Taintor; Seth N Rivera; Hiroyuki Umegaki; Hiroyuki Ikari; George Roth; Donald Ingram; Robert Hitzemann; Joanna S Fowler; S John Gatley; Gene-Jack Wang; Nora D Volkow
DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking.
Alcoholism, clinical and experimental research 2004;28(5):720-8.
2003: Kimberly P Lindsey; S John Gatley; Nora D Volkow
Neuroimaging in drug abuse.
Current psychiatry reports 2003;5(5):355-61.
2003: Joanna S Fowler; Jean Logan; Gene-Jack Wang; Nora D Volkow; Frank Telang; Wei Zhu; Dinko Franceschi; Naomi Pappas; Richard Ferrieri; Colleen Shea; Victor Garza; Youwen Xu; David Schlyer; S John Gatley; Yu-Shin Ding; David Alexoff; Donald Warner; Noelwah Netusil; Pauline Carter; Millard Jayne; Payton King; Paul Vaska
Low monoamine oxidase B in peripheral organs in smokers.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11600-5.
2003: Joanna S Fowler; Jean Logan; Gene-Jack Wang; Dinko Franceschi; Nora D Volkow; Frank Telang; Naomi Pappas; Richard Ferrieri; Colleen Shea; Victor Garza; Youwen Xu; Payton King; David Schlyer; S John Gatley; Yu-Shin Ding; Donald Warner; Noelwah Netusil; Pauline Carter; Millard Jayne; David Alexoff; Wei Zhu; Paul Vaska
Monoamine oxidase A imaging in peripheral organs in healthy human subjects.
Synapse (New York, N.Y.) 2003;49(3):178-87.
2003: S John Gatley
Labeled glucose analogs in the genomic era.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(7):1082-6.
2003: Nora D Volkow; Gene-Jack Wang; Laurence Maynard; Millard Jayne; Joanna S Fowler; Wei Zhu; Jean Logan; S John Gatley; Yu-Shin Ding; Christopher Wong; Naomi Pappas
Brain dopamine is associated with eating behaviors in humans.
The International journal of eating disorders 2003;33(2):136-42.
2003: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Patricia E Molina; Jean Logan; S John Gatley; Andrew N Gifford; Yu-Shin Ding; Christopher Wong; Naomi Pappas; Wei Zhu; James M Swanson
Cardiovascular effects of methylphenidate in humans are associated with increases of dopamine in brain and of epinephrine in plasma.
Psychopharmacology 2003;166(3):264-70.
2002: Andrew N Gifford; Alexandros Makriyannis; Nora D Volkow; S John Gatley
In vivo imaging of the brain cannabinoid receptor.
Chemistry and physics of lipids 2002;121(1-2):65-72.
2002: Nora D Volkow; Gene-Jack Wang; Laurence Maynard; Joanna S Fowler; Budd Jayne; Frank Telang; Jean Logan; Yu-Shin Ding; S John Gatley; Robert Hitzemann; Christopher Wong; Naomi Pappas
Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study.
Psychiatry research 2002;116(3):163-72.
2002: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Yu Shin Ding; S John Gatley
Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: results from imaging studies.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2002;12(6):557-66.
2002: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Panayotis Peter K Thanos; Jean Logan; S John Gatley; Andrew N Gifford; Yu-Shin Ding; Chris Wong; Naomi Pappas; Pether Thanos
Brain DA D2 receptors predict reinforcing effects of stimulants in humans: replication study.
Synapse (New York, N.Y.) 2002;46(2):79-82.
2002: Joanna S Fowler; Jean Logan; Gene-Jack Wang; Nora D Volkow; Wei Zhu; Dinko Franceschi; Naomi Pappas; Richard Ferrieri; Colleen Shea; Victor Garza; Youwen Xu; Robert R MacGregor; David Schlyer; S John Gatley; Yu-Shin Ding; David Alexoff
PET imaging of monoamine oxidase B in peripheral organs in humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2002;43(10):1331-8.
2002: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; Millard Jayne; Dinko Franceschi; Cristopher Wong; S John Gatley; Andrew N Gifford; Yu-Shin Ding; Naomi Pappas
"Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect.
Synapse (New York, N.Y.) 2002;44(3):175-80.
2002: Madina R Gerasimov; Richard Ferrieri; Wynne K Schiffer; Jean Logan; S John Gatley; Andrew N Gifford; David A Alexoff; Douglas A Marsteller; Colleen Shea; Victor Garza; Pauline Carter; Payton King; Charles R Ashby; SA Vitkun; Stephen L Dewey
Study of brain uptake and biodistribution of [11C]toluene in non-human primates and mice.
Life sciences 2002;70(23):2811-28.
2002: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; Dinko Franceschi; Laurence Maynard; Yu-Shin Ding; S John Gatley; Andrew N Gifford; Wei Zhu; James M Swanson
Relationship between blockade of dopamine transporters by oral methylphenidate and the increases in extracellular dopamine: therapeutic implications.
Synapse (New York, N.Y.) 2002;43(3):181-7.
2002: Nora D Volkow; Joanna S Fowler; G Wang; Y Ding; S John Gatley
Mechanism of action of methylphenidate: insights from PET imaging studies.
Journal of attention disorders 2002;6 Suppl 1():S31-43.
2001: Joanna S Fowler; Jean Logan; Yu-Shin Ding; Dinko Franceschi; Gene-Jack Wang; Nora D Volkow; Naomi Pappas; David Schlyer; S John Gatley; David Alexoff; Christoph Felder; Anat Biegon; Wei Zhu
Non-MAO A binding of clorgyline in white matter in human brain.
Journal of neurochemistry 2001;79(5):1039-46.
2001: Nora D Volkow; Linda Chang; Gene-Jack Wang; Joanna S Fowler; Dinko Franceschi; Mark Sedler; S John Gatley; Eric Miller; Robert Hitzemann; Yu-Shin Ding; Jean Logan
Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(23):9414-8.
2001: O V Rice; S John Gatley; J Shen; C L Huemmer; R Rogoz; O T DeJesus; Nora D Volkow; Andrew N Gifford
Effects of endogenous neurotransmitters on the in vivo binding of dopamine and 5-HT radiotracers in mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(5):679-89.
2001: Joanna S Fowler; Yu-Shin Ding; Jean Logan; Robert R MacGregor; Colleen Shea; Victor Garza; R Gimi; Nora D Volkow; Gene-Jack Wang; David Schlyer; Richard Ferrieri; S John Gatley; David Alexoff; Pauline Carter; Payton King; Naomi Pappas; C D Arnett
Species differences in [11C]clorgyline binding in brain.
Nuclear medicine and biology 2001;28(7):779-85.
2001: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; S John Gatley; Jean Logan
[(11)]Cocaine: PET studies of cocaine pharmacokinetics, dopamine transporter availability and dopamine transporter occupancy.
Nuclear medicine and biology 2001;28(5):561-72.
2001: Nora D Volkow; G Wang; Joanna S Fowler; Jean Logan; Madina R Gerasimov; Laurence Maynard; Y Ding; S John Gatley; Andrew N Gifford; Dinko Franceschi
Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(2):RC121.
2001: Jean Logan; Joanna S Fowler; Stephen L Dewey; Nora D Volkow; S John Gatley
A consideration of the dopamine D2 receptor monomer-dimer equilibrium and the anomalous binding properties of the dopamine D2 receptor ligand, N-methyl spiperone.
Journal of neural transmission (Vienna, Austria : 1996) 2001;108(3):279-86.
2000: S John Gatley; Andrew N Gifford; F I Carroll; Nora D Volkow
Sensitivity of binding of high-affinity dopamine receptor radioligands to increased synaptic dopamine.
Synapse (New York, N.Y.) 2000;38(4):483-8.
2000: M Cosenza; Andrew N Gifford; S John Gatley; Bea Pyatt; Q Liu; Alexandros Makriyannis; Nora D Volkow
Locomotor activity and occupancy of brain cannabinoid CB1 receptors by the antagonist/inverse agonist AM281.
Synapse (New York, N.Y.) 2000;38(4):477-82.
2000: Andrew N Gifford; M H Park; Thomas Kash; L M Herman; E H Park; S John Gatley; Nora D Volkow
Effect of amphetamine-induced dopamine release on radiotracer binding to D1 and D2 receptors in rat brain striatal slices.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(4-5):413-8.
2000: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; William D Rooney; Christoph Felder; Jing-Huei Lee; Dinko Franceschi; Laurence Maynard; David Schlyer; Jullie W Pan; S John Gatley; C S Springer Jr
Resting brain metabolic activity in a 4 tesla magnetic field.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2000;44(5):701-5.
2000: Andrew N Gifford; Magalie Bruneus; S John Gatley; Nora D Volkow
Cannabinoid receptor-mediated inhibition of acetylcholine release from hippocampal and cortical synaptosomes.
British journal of pharmacology 2000;131(3):645-50.
2000: Madina R Gerasimov; M Franceschi; Nora D Volkow; Andrew N Gifford; S John Gatley; Douglas A Marsteller; Patricia E Molina; Stephen L Dewey
Comparison between intraperitoneal and oral methylphenidate administration: A microdialysis and locomotor activity study.
The Journal of pharmacology and experimental therapeutics 2000;295(1):51-7.
2000: Nora D Volkow; Gene-Jack Wang; MW Fischman; RW Foltin; Joanna S Fowler; D Franceschi; M Franceschi; Jean Logan; S John Gatley; Cristopher Wong; Yu-Shin Ding; Robert Hitzemann; Naomi Pappas
Effects of route of administration on cocaine induced dopamine transporter blockade in the human brain.
Life sciences 2000;67(12):1507-15.
2000: Nora D Volkow; S John Gatley; Joanna S Fowler; Gene-Jack Wang; J Swanson
Serotonin and the therapeutic effects of ritalin.
Science (New York, N.Y.) 2000;288(5463):11.
2000: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Dinko Franceschi; Panayotis K Thanos; Cristopher Wong; S John Gatley; Yu-Shin Ding; P Molina; David Schlyer; David Alexoff; Robert Hitzemann; Naomi Pappas
Cocaine abusers show a blunted response to alcohol intoxication in limbic brain regions.
Life sciences 2000;66(12):PL161-7.
2000: Nora D Volkow; Jean Logan; Joanna S Fowler; Gene-Jack Wang; R C Gur; Christopher Wong; C Felder; S John Gatley; Yu-Shin Ding; Robert Hitzemann; Naomi Pappas
Association between age-related decline in brain dopamine activity and impairment in frontal and cingulate metabolism.
The American journal of psychiatry 2000;157(1):75-80.
1999: Andrew N Gifford; Magalie Bruneus; S Lin; A Goutopoulos; Alexandros Makriyannis; Nora D Volkow; S John Gatley
Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374).
European journal of pharmacology 1999;383(1):9-14.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; S John Gatley; Cristopher Wong; Robert Hitzemann; Naomi Pappas
Reinforcing effects of psychostimulants in humans are associated with increases in brain dopamine and occupancy of D(2) receptors.
The Journal of pharmacology and experimental therapeutics 1999;291(1):409-15.
1999: S John Gatley; Nora D Volkow; Andrew N Gifford; Joanna S Fowler; Stephen L Dewey; Yu-Shin Ding; Jean Logan
Dopamine-transporter occupancy after intravenous doses of cocaine and methylphenidate in mice and humans.
Psychopharmacology 1999;146(1):93-100.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; S John Gatley; A Gifford; Robert Hitzemann; Yu-Shin Ding; Naomi Pappas
Prediction of reinforcing responses to psychostimulants in humans by brain dopamine D2 receptor levels.
The American journal of psychiatry 1999;156(9):1440-3.
1999: Andrew N Gifford; Magalie Bruneus; S John Gatley; R Lan; Alexandros Makriyannis; Nora D Volkow
Large receptor reserve for cannabinoid actions in the central nervous system.
The Journal of pharmacology and experimental therapeutics 1999;288(2):478-83.
1999: Nora D Volkow; Joanna S Fowler; Yu-Shin Ding; Gene-Jack Wang; S John Gatley
Imaging the neurochemistry of nicotine actions: studies with positron emission tomography.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 1999;1 Suppl 2():S127-32; discussion S139-40.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; MW Fischman; RW Foltin; Naji N Abumrad; S John Gatley; Jean Logan; Cristopher Wong; Andrew N Gifford; Yu-Shin Ding; Robert Hitzemann; Naomi Pappas
Methylphenidate and cocaine have a similar in vivo potency to block dopamine transporters in the human brain.
Life sciences 1999;65(1):PL7-12.
1999: Nora D Volkow; Joanna S Fowler; S John Gatley; Stephen L Dewey; Gene-Jack Wang; Jean Logan; Yu-Shin Ding; Dinko Franceschi; Andrew N Gifford; A Morgan; Naomi Pappas; Payton King
Comparable changes in synaptic dopamine induced by methylphenidate and by cocaine in the baboon brain.
Synapse (New York, N.Y.) 1999;31(1):59-66.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Robert Hitzemann; B Angrist; S John Gatley; Jean Logan; Yu-Shin Ding; Naomi Pappas
Association of methylphenidate-induced craving with changes in right striato-orbitofrontal metabolism in cocaine abusers: implications in addiction.
The American journal of psychiatry 1999;156(1):19-26.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; S John Gatley; Jean Logan; Yu-Shin Ding; Stephen L Dewey; Robert Hitzemann; Andrew N Gifford; Naomi Pappas
Blockade of striatal dopamine transporters by intravenous methylphenidate is not sufficient to induce self-reports of "high".
The Journal of pharmacology and experimental therapeutics 1999;288(1):14-20.
1998: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; S John Gatley; Jean Logan; Yu-Shin Ding; Robert Hitzemann; Naomi Pappas
Dopamine transporter occupancies in the human brain induced by therapeutic doses of oral methylphenidate.
The American journal of psychiatry 1998;155(10):1325-31.
1998: S John Gatley; Yu-Shin Ding; D Brady; Andrew N Gifford; Stephen L Dewey; F I Carroll; Joanna S Fowler; Nora D Volkow
In vitro and ex vivo autoradiographic studies of nicotinic acetylcholine receptors using [18F]fluoronochloroepibatidine in rodent and human brain.
Nuclear medicine and biology 1998;25(5):449-54.
1998: S John Gatley; Nora D Volkow
Addiction and imaging of the living human brain.
Drug and alcohol dependence 1998;51(1-2):97-108.
1998: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Robert Hitzemann; S John Gatley; S S Dewey; Naomi Pappas
Enhanced sensitivity to benzodiazepines in active cocaine-abusing subjects: a PET study.
The American journal of psychiatry 1998;155(2):200-6.
1998: Andrew N Gifford; S John Gatley; Nora D Volkow
Evaluation of the importance of rebinding to receptors in slowing the approach to equilibrium of high-affinity PET and SPECT radiotracers.
Synapse (New York, N.Y.) 1998;28(2):167-75.
1998: Joanna S Fowler; Nora D Volkow; Jean Logan; S John Gatley; Naomi Pappas; Payton King; Yu-Shin Ding; Gene-Jack Wang
Measuring dopamine transporter occupancy by cocaine in vivo: radiotracer considerations.
Synapse (New York, N.Y.) 1998;28(2):111-6.
1998: Yu-Shin Ding; Jean Logan; S John Gatley; Joanna S Fowler; Nora D Volkow
PET studies of peripheral catechol-O-methyltransferase in non-human primates using [18F]Ro41-0960.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(10-12):1199-211.
1998: Joanna S Fowler; Nora D Volkow; Jean Logan; Naomi Pappas; Payton King; R MacGregor; Colleen Shea; Victor Garza; S John Gatley
An acute dose of nicotine does not inhibit MAO B in baboon brain in vivo.
Life sciences 1998;63(2):PL19-23.
1998: S John Gatley; R Lan; Nora D Volkow; Naomi Pappas; Payton King; Christopher T Wong; Andrew N Gifford; Bea Pyatt; Stephen L Dewey; Alexandros Makriyannis
Imaging the brain marijuana receptor: development of a radioligand that binds to cannabinoid CB1 receptors in vivo.
Journal of neurochemistry 1998;70(1):417-23.
1997: Jean Logan; Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; MW Fischman; RW Foltin; Naji N Abumrad; SA Vitkun; S John Gatley; Naomi Pappas; Robert Hitzemann; C E Shea
Concentration and occupancy of dopamine transporters in cocaine abusers with [11C]cocaine and PET.
Synapse (New York, N.Y.) 1997;27(4):347-56.
1997: Andrew N Gifford; Y Tang; S John Gatley; Nora D Volkow; R Lan; Alexandros Makriyannis
Effect of the cannabinoid receptor SPECT agent, AM 281, on hippocampal acetylcholine release from rat brain slices.
Neuroscience letters 1997;238(1-2):84-6.
1997: Patricia E Molina; Yu-Shin Ding; F I Carroll; F Liang; Nora D Volkow; Naomi Pappas; Michael J Kuhar; N Abumrad; S John Gatley; Joanna S Fowler
Fluoro-norchloroepibatidine: preclinical assessment of acute toxicity.
Nuclear medicine and biology 1997;24(8):743-7.
1997: Yu-Shin Ding; Joanna S Fowler; Nora D Volkow; Stephen L Dewey; Gene-Jack Wang; Jean Logan; S John Gatley; Naomi Pappas
Chiral drugs: comparison of the pharmacokinetics of [11C]d-threo and L-threo-methylphenidate in the human and baboon brain.
Psychopharmacology 1997;131(1):71-8.
1997: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; S John Gatley; Robert Hitzemann; A D Chen; Stephen L Dewey; Naomi Pappas
Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects.
Nature 1997;386(6627):830-3.
1997: Nora D Volkow; Gene-Jack Wang; MW Fischman; RW Foltin; Joanna S Fowler; Naji N Abumrad; SA Vitkun; Jean Logan; S John Gatley; Naomi Pappas; Robert Hitzemann; C E Shea
Relationship between subjective effects of cocaine and dopamine transporter occupancy.
Nature 1997;386(6627):827-30.
1997: Andrew N Gifford; L Samiian; S John Gatley; Charles R Ashby
Examination of the effect of the cannabinoid receptor agonist, CP 55,940, on electrically evoked transmitter release from rat brain slices.
European journal of pharmacology 1997;324(2-3):187-92.
1997: S John Gatley; Nora D Volkow; Andrew N Gifford; Yu-Shin Ding; Jean Logan; Gene-Jack Wang
Model for estimating dopamine transporter occupancy and subsequent increases in synaptic dopamine using positron emission tomography and carbon-11-labeled cocaine.
Biochemical pharmacology 1997;53(1):43-52.
1997: S John Gatley; R Lan; Bea Pyatt; Andrew N Gifford; Nora D Volkow; Alexandros Makriyannis
Binding of the non-classical cannabinoid CP 55,940, and the diarylpyrazole AM251 to rodent brain cannabinoid receptors.
Life sciences 1997;61(14):PL 191-7.
1996: Yu-Shin Ding; S John Gatley; Joanna S Fowler; Nora D Volkow; D Aggarwal; Jean Logan; Stephen L Dewey; F Liang; F I Carroll; Michael J Kuhar
Mapping nicotinic acetylcholine receptors with PET.
Synapse (New York, N.Y.) 1996;24(4):403-7.
1996: Nora D Volkow; S John Gatley; Joanna S Fowler; Jean Logan; MW Fischman; Andrew N Gifford; Naomi Pappas; Payton King; SA Vitkun; Yu-Shin Ding; Gene-Jack Wang
Cocaine doses equivalent to those abused by humans occupy most of the dopamine transporters.
Synapse (New York, N.Y.) 1996;24(4):399-402.
1996: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; S John Gatley; Yu-Shin Ding; Jean Logan; Stephen L Dewey; Robert Hitzemann; J Lieberman
Relationship between psychostimulant-induced "high" and dopamine transporter occupancy.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10388-92.
1996: S John Gatley; Andrew N Gifford; Nora D Volkow; R Lan; Alexandros Makriyannis
123I-labeled AM251: a radioiodinated ligand which binds in vivo to mouse brain cannabinoid CB1 receptors.
European journal of pharmacology 1996;307(3):331-8.
1996: Nora D Volkow; Joanna S Fowler; S John Gatley; Jean Logan; Gene-Jack Wang; Yu-Shin Ding; Stephen L Dewey
PET evaluation of the dopamine system of the human brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(7):1242-56.
1996: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; S John Gatley; Robert R MacGregor; David Schlyer; Robert Hitzemann; AP Wolf
Measuring age-related changes in dopamine D2 receptors with 11C-raclopride and 18F-N-methylspiroperidol.
Psychiatry research 1996;67(1):11-6.
1996: Igor I Galynker; David Schlyer; Stephen L Dewey; Joanna S Fowler; Jean Logan; S John Gatley; Robert R MacGregor; R A Ferrieri; M J Holland; Jonathan D Brodie; E Simon; AP Wolf
Opioid receptor imaging and displacement studies with [6-O-[11C] methyl]buprenorphine in baboon brain.
Nuclear medicine and biology 1996;23(3):325-31.
1996: Nora D Volkow; Yu-Shin Ding; Joanna S Fowler; Gene-Jack Wang; Jean Logan; S John Gatley; Robert Hitzemann; Gwenn S Smith; S D Fields; R Gur
Dopamine transporters decrease with age.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(4):554-9.
1996: Andrew N Gifford; S John Gatley; Charles R Ashby
Endogenously released dopamine inhibits the binding of dopaminergic PET and SPECT ligands in superfused rat striatal slices.
Synapse (New York, N.Y.) 1996;22(3):232-8.
1996: S John Gatley; Nora D Volkow; R Chen; Joanna S Fowler; F I Carroll; Michael J Kuhar
Displacement of RTI-55 from the dopamine transporter by cocaine.
European journal of pharmacology 1996;296(2):145-51.
1996: Yu-Shin Ding; S John Gatley; Joanna S Fowler; R Chen; Nora D Volkow; Jean Logan; C E Shea; Y Sugano; J Koomen
Mapping catechol-O-methyltransferase in vivo: initial studies with [18F]Ro41-0960.
Life sciences 1996;58(3):195-208.
1996: K A Yousef; Joanna S Fowler; Nora D Volkow; Stephen L Dewey; Colleen Shea; David Schlyer; S John Gatley; Jean Logan; AP Wolf
[18F]haloperidol binding in baboon brain in vivo.
Nuclear medicine and biology 1996;23(1):47-52.
1996: S John Gatley; D Pan; R Chen; G Chaturvedi; Yu-Shin Ding
Affinities of methylphenidate derivatives for dopamine, norepinephrine and serotonin transporters.
Life sciences 1996;58(12):231-9.
1996: Nora D Volkow; Gene-Jack Wang; S John Gatley; Joanna S Fowler; Yu-Shin Ding; Jean Logan; Robert Hitzemann; B Angrist; J Lieberman
Temporal relationships between the pharmacokinetics of methylphenidate in the human brain and its behavioral and cardiovascular effects.
Psychopharmacology 1996;123(1):26-33.
1996: S John Gatley; S M Meehan; R Chen; D F Pan; M D Schechter; Stephen L Dewey
Place preference and microdialysis studies with two derivatives of methylphenidate.
Life sciences 1996;58(24):PL345-52.
1995: Yu-Shin Ding; Joanna S Fowler; Nora D Volkow; Jean Logan; S John Gatley; Y Sugano
Carbon-11-d-threo-methylphenidate binding to dopamine transporter in baboon brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(12):2298-305.
1995: David Alexoff; Colleen Shea; Joanna S Fowler; Payton King; S John Gatley; David Schlyer; AP Wolf
Plasma input function determination for PET using a commercial laboratory robot.
Nuclear medicine and biology 1995;22(7):893-904.
1995: S John Gatley; Yu-Shin Ding; Nora D Volkow; R Chen; Y Sugano; Joanna S Fowler
Binding of d-threo-[11C]methylphenidate to the dopamine transporter in vivo: insensitivity to synaptic dopamine.
European journal of pharmacology 1995;281(2):141-9.
1995: Yu-Shin Ding; Joanna S Fowler; S John Gatley; Jean Logan; Nora D Volkow; Colleen Shea
Mechanistic positron emission tomography studies of 6-[18F]fluorodopamine in living baboon heart: selective imaging and control of radiotracer metabolism using the deuterium isotope effect.
Journal of neurochemistry 1995;65(2):682-90.
1995: Nora D Volkow; Joanna S Fowler; Jean Logan; S John Gatley; Stephen L Dewey; Robert R MacGregor; David Schlyer; Naomi Pappas; Payton King; Gene-Jack Wang
Carbon-11-cocaine binding compared at subpharmacological and pharmacological doses: a PET study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1289-97.
1995: S John Gatley; Nora D Volkow; Joanna S Fowler; Stephen L Dewey; Jean Logan
Sensitivity of striatal [11C]cocaine binding to decreases in synaptic dopamine.
Synapse (New York, N.Y.) 1995;20(2):137-44.
1995: Nora D Volkow; S John Gatley; Joanna S Fowler; R Chen; Jean Logan; Stephen L Dewey; Yu-Shin Ding; Naomi Pappas; Payton King; Robert R MacGregor
Long-lasting inhibition of in vivo cocaine binding to dopamine transporters by 3 beta-(4-iodophenyl)tropane-2-carboxylic acid methyl ester: RTI-55 or beta CIT.
Synapse (New York, N.Y.) 1995;19(3):206-11.
1995: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; Yu-Shin Ding; Jean Logan; S John Gatley; Robert R MacGregor; AP Wolf
Comparison of two pet radioligands for imaging extrastriatal dopamine transporters in human brain.
Life sciences 1995;57(14):PL187-91.
1994: Jean Logan; Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Stephen L Dewey; R MacGregor; David Schlyer; S John Gatley; Naomi Pappas; Payton King
Effects of blood flow on [11C]raclopride binding in the brain: model simulations and kinetic analysis of PET data.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(6):995-1010.
1994: D Pan; S John Gatley; Stephen L Dewey; R Chen; D A Alexoff; Yu-Shin Ding; Joanna S Fowler
Binding of bromine-substituted analogs of methylphenidate to monoamine transporters.
European journal of pharmacology 1994;264(2):177-82.
1994: Yu-Shin Ding; Joanna S Fowler; Nora D Volkow; S John Gatley; Jean Logan; Stephen L Dewey; David Alexoff; E Fazzini; AP Wolf
Pharmacokinetics and in vivo specificity of [11C]dl-threo-methylphenidate for the presynaptic dopaminergic neuron.
Synapse (New York, N.Y.) 1994;18(2):152-60.
1994: S John Gatley; D W Yu; Joanna S Fowler; Robert R MacGregor; David Schlyer; Stephen L Dewey; AP Wolf; T Martin; C E Shea; Nora D Volkow
Studies with differentially labeled [11C]cocaine, [11C]norcocaine, [11C]benzoylecgonine, and [11C]- and 4'-[18F]fluorococaine to probe the extent to which [11C]cocaine metabolites contribute to PET images of the baboon brain.
Journal of neurochemistry 1994;62(3):1154-62.
1993: S John Gatley
Estimation of upper limits on human radiation absorbed doses from carbon-11-labeled compounds.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(12):2208-15.
1993: S John Gatley; R A Ferrieri; Joanna S Fowler; Robert R MacGregor; AP Wolf
Rapid radiochemical and chemical quality control of [11C]putrescine.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1993;44(4):765-7.
1993: Yu-Shin Ding; Joanna S Fowler; Stephen L Dewey; Jean Logan; David Schlyer; S John Gatley; Nora D Volkow; P T King; AP Wolf
Comparison of high specific activity (-) and (+)-6-[18F]fluoronorepinephrine and 6-[18F]fluorodopamine in baboons: heart uptake, metabolism and the effect of desipramine.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(4):619-29.
1993: Yu-Shin Ding; Joanna S Fowler; Stephen L Dewey; AP Wolf; Jean Logan; S John Gatley; Nora D Volkow; Colleen Shea; D P Taylor
Synthesis and PET studies of fluorine-18-BMY 14802: a potential antipsychotic drug.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(2):246-54.
1992: Joanna S Fowler; Nora D Volkow; Robert R MacGregor; Jean Logan; Stephen L Dewey; S John Gatley; AP Wolf
Comparative PET studies of the kinetics and distribution of cocaine and cocaethylene in baboon brain.
Synapse (New York, N.Y.) 1992;12(3):220-7.
1992: D W Yu; S John Gatley; AP Wolf; Robert R MacGregor; Stephen L Dewey; Joanna S Fowler; David Schlyer
Synthesis of carbon-11 labeled iodinated cocaine derivatives and their distribution in baboon brain measured using positron emission tomography.
Journal of medicinal chemistry 1992;35(12):2178-83.
1991: Jean Logan; Stephen L Dewey; AP Wolf; Joanna S Fowler; Jonathan D Brodie; B Angrist; Nora D Volkow; S John Gatley
Effects of endogenous dopamine on measures of [18F]N-methylspiroperidol binding in the basal ganglia: comparison of simulations and experimental results from PET studies in baboons.
Synapse (New York, N.Y.) 1991;9(3):195-207.
1991: S John Gatley
Activities of the enantiomers of cocaine and some related compounds as substrates and inhibitors of plasma butyrylcholinesterase.
Biochemical pharmacology 1991;41(8):1249-54.
1991: Yu-Shin Ding; Joanna S Fowler; S John Gatley; Stephen L Dewey; AP Wolf; David Schlyer
Synthesis of high specific activity 6-[18F]fluorodopamine for positron emission tomography studies of sympathetic nervous tissue.
Journal of medicinal chemistry 1991;34(2):861-3.
1991: Yu-Shin Ding; Joanna S Fowler; S John Gatley; Stephen L Dewey; AP Wolf
Synthesis of high specific activity (+)- and (-)-6-[18F]fluoronorepinephrine via the nucleophilic aromatic substitution reaction.
Journal of medicinal chemistry 1991;34(2):767-71.
1991: Nora D Volkow; N Mullani; L K Gould; S S Adler; S John Gatley
Sensitivity of measurements of regional brain activation with oxygen-15-water and PET to time of stimulation and period of image reconstruction.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(1):58-61.
1991: David Alexoff; Joanna S Fowler; S John Gatley
Removal of the 2.2.2 cryptand (Kryptofix 2.2.2) from 18FDG by cation exchange.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1991;42(12):1189-93.
1991: S John Gatley; R Franceschini; R Ferrieri; D J Schyler; AP Wolf
An improved synthesis of the inert, diffusible blood-flow tracer, [18F]fluoromethane.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1991;42(11):1049-53.
1991: S John Gatley; Colleen Shea
Radiochemical and chemical quality-assurance methods for [13N]-ammonia made from a small volume H2(16)O target.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1991;42(9):793-6.
1990: Jean Logan; Joanna S Fowler; Nora D Volkow; AP Wolf; Stephen L Dewey; David Schlyer; Robert R MacGregor; Robert Hitzemann; B Bendriem; S John Gatley
Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(5):740-7.
1990: S John Gatley; Robert R MacGregor; Joanna S Fowler; AP Wolf; Stephen L Dewey; David Schlyer
Rapid stereoselective hydrolysis of (+)-cocaine in baboon plasma prevents its uptake in the brain: implications for behavioral studies.
Journal of neurochemistry 1990;54(2):720-3.
1990: Stephen L Dewey; Robert R MacGregor; Jonathan D Brodie; B Bendriem; P T King; Nora D Volkow; David Schlyer; Joanna S Fowler; AP Wolf; S John Gatley
Mapping muscarinic receptors in human and baboon brain using [N-11C-methyl]-benztropine.
Synapse (New York, N.Y.) 1990;5(3):213-23.
1989: Joanna S Fowler; Nora D Volkow; AP Wolf; Stephen L Dewey; David Schlyer; Robert R MacGregor; Robert Hitzemann; Jean Logan; B Bendriem; S John Gatley
Mapping cocaine binding sites in human and baboon brain in vivo.
Synapse (New York, N.Y.) 1989;4(4):371-7.