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Jean-François Gaussin

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Tumor Cell Line

Procedures

Physiology

Gene Expression Regulation, Neoplastic

Disorders

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Publications

TOP 3
Véronique Mathieu; Christine Pirker; Elisabeth Martin De Lassalle; Mathieu Vernier; Tatjana Mijatovic; Nancy DeNeve; Jean-François Gaussin; Mischael Dehoux; Florence Lefranc; Walter Berger; Robert Kiss
The sodium pump alpha1 sub-unit: a disease progression-related target for metastatic melanoma treatment.
Véronique Mathieu; Nancy De Nève; Marie Le Mercier; Janique Dewelle; Jean-François Gaussin; Mischael Dehoux; Robert Kiss; Florence Lefranc
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model.
Eric Van Quaquebeke; Tine Mahieu; Patrick Dumont; Janique Dewelle; Fabrice Ribaucour; Gentiane Simon; Sébastien Sauvage; Jean-François Gaussin; Jérôme Tuti; Mohamed El Yazidi; Frank Van Vynckt; Tatjana Mijatovic; Florence Lefranc; Francis Darro; Robert Kiss
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.

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All Publications

2009: Véronique Mathieu; Christine Pirker; Elisabeth Martin De Lassalle; Mathieu Vernier; Tatjana Mijatovic; Nancy DeNeve; Jean-François Gaussin; Mischael Dehoux; Florence Lefranc; Walter Berger; Robert Kiss
The sodium pump alpha1 sub-unit: a disease progression-related target for metastatic melanoma treatment.
Journal of cellular and molecular medicine 2009;13(9B):3960-72.
2008: Véronique Mathieu; Nancy De Nève; Marie Le Mercier; Janique Dewelle; Jean-François Gaussin; Mischael Dehoux; Robert Kiss; Florence Lefranc
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model.
Neoplasia (New York, N.Y.) 2008;10(12):1383-92.
2007: Eric Van Quaquebeke; Tine Mahieu; Patrick Dumont; Janique Dewelle; Fabrice Ribaucour; Gentiane Simon; Sébastien Sauvage; Jean-François Gaussin; Jérôme Tuti; Mohamed El Yazidi; Frank Van Vynckt; Tatjana Mijatovic; Florence Lefranc; Francis Darro; Robert Kiss
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.
Journal of medicinal chemistry 2007;50(17):4122-34.
2006: Tatjana Mijatovic; Véronique Mathieu; Jean-François Gaussin; Nancy De Nève; Fabrice Ribaucour; Eric Van Quaquebeke; Patrick Dumont; Francis Darro; Robert Kiss
Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers.
Neoplasia (New York, N.Y.) 2006;8(5):402-12.
2005: Francis Darro; Christine Decaestecker; Jean-François Gaussin; Steven Mortier; Rob Van Ginckel; Robert Kiss
Are syngeneic mouse tumor models still valuable experimental models in the field of anti-cancer drug discovery?
International journal of oncology 2005;27(3):607-16.
2005: Florence Lefranc; Syril James; Isabelle Camby; Jean-François Gaussin; Francis Darro; Jacques Brotchi; Joachim Gabius; Robert Kiss
Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts.
Journal of neurosurgery 2005;102(4):706-14.
2004: Anne Mathieu; Myriam Remmelink; Nicky D'Haene; Stanislas Penant; Jean-François Gaussin; Rob Van Ginckel; Francis Darro; Robert Kiss; Isabelle Salmon
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione-S-transferase-alpha (GST)-alpha, GST-mu, and GST-pi.
Cancer 2004;101(8):1908-18.

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