FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Simon Gayther

Research Profile

Disorders

Physiology

Genes & Molecular Sequences

Chemicals & Drugs

Procedures

Concepts & Ideas

Risk Factors

Co-author Network

Publications

TOP 3
Elizabeth M Poole; Susan J Ramus; Joellen M Schildkraut; Rebecca Sutphen; Kathryn L Terry; Ya-Yu Tsai; Jonathan Tyrer; Robert A Vierkant; Rachel T Palmieri Weber; Nicolas Wentzensen; Hannah P Yang; STEPHEN CHANOCK; Daniel W Cramer; Julie M Cunningham; Brooke L Fridley; Margaret A Gates; Simon A Gayther; Ellen L Goode; Brigit A High; Edwin S Iversen; Jolanta Lissowska; Paul D P Pharoah; Catherine M Phelan; Shelley S Tworoger
ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association Consortium.
Simon A Gayther
Inherited risk of ovarian cancer and the implications for screening.
Brooke L Fridley; Simon A Gayther; Aleksandra Gentry-Maharaj; Kelly L Bolton; Y Ann Chen; Zhihua Chen; Julie M Cunningham; David Fenstermacher; Lynn C Hartmann; Ed Iversen; Gregory D Jenkins; Usha Menon; Paul D P Pharoah; Susan J Ramus; Joellen Schildkraut; Thomas A Sellers; Honglin Song; Rebecca Sutphen; Ya-Yu Tsai; Jonathan Tyrer; Robert A Vierkant; Ellen L Goode
Gene set analysis of survival following ovarian cancer implicates macrolide binding and intracellular signaling genes.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Simon Gayther (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Elizabeth M Poole; Susan J Ramus; Joellen M Schildkraut; Rebecca Sutphen; Kathryn L Terry; Ya-Yu Tsai; Jonathan Tyrer; Robert A Vierkant; Rachel T Palmieri Weber; Nicolas Wentzensen; Hannah P Yang; STEPHEN CHANOCK; Daniel W Cramer; Julie M Cunningham; Brooke L Fridley; Margaret A Gates; Simon A Gayther; Ellen L Goode; Brigit A High; Edwin S Iversen; Jolanta Lissowska; Paul D P Pharoah; Catherine M Phelan; Shelley S Tworoger
ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association Consortium.
Cancer causes & control : CCC 2012;23(11):1805-10.
2012: Simon A Gayther
Inherited risk of ovarian cancer and the implications for screening.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2012;22 Suppl 1():S12-5.
2012: Brooke L Fridley; Simon A Gayther; Aleksandra Gentry-Maharaj; Kelly L Bolton; Y Ann Chen; Zhihua Chen; Julie M Cunningham; David Fenstermacher; Lynn C Hartmann; Ed Iversen; Gregory D Jenkins; Usha Menon; Paul D P Pharoah; Susan J Ramus; Joellen Schildkraut; Thomas A Sellers; Honglin Song; Rebecca Sutphen; Ya-Yu Tsai; Jonathan Tyrer; Robert A Vierkant; Ellen L Goode
Gene set analysis of survival following ovarian cancer implicates macrolide binding and intracellular signaling genes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2012;21(3):529-36.
2012: Kristin L White; Hannah P Yang; Andrew Berchuck; Michael J Birrer; Bridget Charbonneau; Mine S Cicek; Julie M Cunningham; Brooke L Fridley; Montserrat Garcia-Closas; Simon A Gayther; Ellen L Goode; Edwin S Iversen; Rachel T Palmieri; Paul P D Pharoah; Catherine M Phelan; Susan J Ramus; David N Rider; Joellen M Schildkraut; Thomas A Sellers; Honglin Song; Rebecca Sutphen; Jonathan Tyrer; Robert A Vierkant; Nicolas Wentzensen
Ovarian cancer risk associated with inherited inflammation-related variants.
Cancer research 2012;72(5):1064-9.
2012: Kate Lawrenson; Barbara Grun; Simon A Gayther
Heterotypic three-dimensional in vitro modeling of stromal-epithelial interactions during ovarian cancer initiation and progression.
Journal of visualized experiments : JoVE 2012;(66):e4206.
2011: Kate Lawrenson; Maria Notaridou; Andrew Sims; Duncan Sproul; Elizabeth Benjamin; Dimitra Dafou; Barbara Grun; Ian J Jacobs; Simon A Gayther
Modelling genetic and clinical heterogeneity in epithelial ovarian cancers.
Carcinogenesis 2011;32(10):1540-9.
2011: Matthew L Freedman; Alvaro N A Monteiro; Simon A Gayther; Gerhard A Coetzee; Angela Risch; Christoph Plass; Graham Casey; Mariella De Biasi; Chris Carlson; David Duggan; Michael James; Pengyuan Liu; Jay W Tichelaar; Haris G Vikis; Ming You; Ian G Mills
Principles for the post-GWAS functional characterization of cancer risk loci.
Nature genetics 2011;43(6):513-8.
2011: Nyaladzi Balogun; Aleksandra Gentry-Maharaj; Eva L Wozniak; Anita Lim; Andy Ryan; Susan J Ramus; Jeremy Ford; Matthew Burnell; Martin Widschwendter; Sue F Gessler; Simon A Gayther; Ian J Jacobs; Usha Menon
Recruitment of newly diagnosed ovarian cancer patients proved challenging in a multicentre biobanking study.
Journal of clinical epidemiology 2011;64(5):525-30.
2011: John Sinclair; Gergana Metodieva; Dimitra Dafou; Simon A Gayther; John Francis Timms
Profiling signatures of ovarian cancer tumour suppression using 2D-DIGE and 2D-LC-MS/MS with tandem mass tagging.
Journal of proteomics 2011;74(4):451-65.
2011: Galina Lurie; Lynne R Wilkens; Pamela J Thompson; Michael E Carney; Rachel T Palmieri; Paul D P Pharoah; Honglin Song; Estrid Hogdall; Susanne Kruger Kjaer; Richard A DiCioccio; Valerie McGuire; Alice S Whittemore; Simon A Gayther; Aleksandra Gentry-Maharaj; Usha Menon; Susan J Ramus; Marc T Goodman
Vitamin D receptor rs2228570 polymorphism and invasive ovarian carcinoma risk: pooled analysis in five studies within the Ovarian Cancer Association Consortium.
International journal of cancer. Journal international du cancer 2011;128(4):936-43.
2011: Jyotsna Batra; Christina M Nagle; Tracy O'Mara; Melanie Higgins; Ying Dong; Olivia L Tan; Felicity Lose; Lene Marie Skeie; Srilakshmi Srinivasan; Kelly L Bolton; Honglin Song; Susan J Ramus; Simon A Gayther; Paul D P Pharoah; Mary-Anne Kedda; Amanda B Spurdle; Judith A Clements
A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival.
BMC cancer 2011;11():119.
2011: Aimee M Near; Anna H Wu; Claire Templeman; David J Van Den Berg; Jennifer A Doherty; Mary Anne Rossing; Ellen L Goode; Julie M Cunningham; Robert A Vierkant; Brooke L Fridley; Georgia Chenevix-Trench; Penelope M Webb; Susanne Krüger Kjaer; Estrid Hogdall; Simon A Gayther; Susan J Ramus; Usha Menon; Aleksandra Gentry-Maharaj; Joellen M Schildkraut; Patricia G Moorman; Rachel T Palmieri; Roberta B Ness; Kirsten B Moysich; Daniel W Cramer; Kathryn L Terry; Allison F Vitonis; Malcolm C Pike; Andrew Berchuck; Celeste L Pearce
Progesterone receptor gene polymorphisms and risk of endometriosis: results from an international collaborative effort.
Fertility and sterility 2011;95(1):40-5.
2010: Felicity Lose; Christina M Nagle; Tracy O'Mara; Jyotsna Batra; Kelly L Bolton; Honglin Song; Susan J Ramus; Aleksandra Gentry-Maharaj; Usha Menon; Simon A Gayther; Paul D P Pharoah; Mary-Anne Kedda; Amanda B Spurdle
Vascular endothelial growth factor gene polymorphisms and ovarian cancer survival.
Gynecologic oncology 2010;119(3):479-83.
2010: Dimitra Dafou; Barbara Grun; John Sinclair; Kate Lawrenson; Elizabeth C Benjamin; Estrid Hogdall; Susanne Kruger-Kjaer; Lise Christensen; Heidi M Sowter; Ahmed Al-Attar; Richard Edmondson; Stephen Darby; Andrew Berchuck; Peter W Laird; Celeste L Pearce; Susan J Ramus; Ian J Jacobs; Simon A Gayther
Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers.
Neoplasia (New York, N.Y.) 2010;12(7):579-89.
2010: Simon A Gayther; Paul D P Pharoah
The inherited genetics of ovarian and endometrial cancer.
Current opinion in genetics & development 2010;20(3):231-8.
2010: Kate Lawrenson; Barbara Grun; Elizabeth Benjamin; Ian J Jacobs; Dimitra Dafou; Simon A Gayther
Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer.
Neoplasia (New York, N.Y.) 2010;12(4):317-25.
2010: Andrew E Teschendorff; Usha Menon; Aleksandra Gentry-Maharaj; Susan J Ramus; Daniel J Weisenberger; Hui Shen; Mihaela Campan; Houtan Noushmehr; Christopher G Bell; A Peter Maxwell; David A Savage; Elisabeth Mueller-Holzner; Christian Marth; Gabrijela Kocjan; Simon A Gayther; Allison Jones; Stephan Beck; Wolfgang Wagner; Peter W Laird; Ian J Jacobs; Martin Widschwendter
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
Genome research 2010;20(4):440-6.
2010: Kathryn L Terry; Allison F Vitonis; Dena Hernandez; Galina Lurie; Honglin Song; Susan J Ramus; Linda Titus-Ernstoff; Michael E Carney; Lynne R Wilkens; Aleksandra Gentry-Maharaj; Usha Menon; Simon A Gayther; Paul D Pharaoh; Marc T Goodman; Daniel W Cramer; Michael J Birrer
A polymorphism in the GALNT2 gene and ovarian cancer risk in four population based case-control studies.
International journal of molecular epidemiology and genetics 2010;1(4):272-7.
2010: Sheetal Dyall; Simon A Gayther; Dimitra Dafou
Cancer stem cells and epithelial ovarian cancer.
Journal of oncology 2010;2010():105269.
2009: Julie M Cunningham; Robert A Vierkant; Thomas A Sellers; C Phelan; D N Rider; Mark Liebow; Joellen M Schildkraut; Andrew Berchuck; Fergus J. Couch; Xianshu Wang; Brooke L Fridley; A Gentry-Maharaj; Usha Menon; Estrid Hogdall; Susanne Krüger Kjaer; A Whittemore; Richard A DiCioccio; H Song; Simon A Gayther; S J Ramus; P D P Pharaoh; Ellen L Goode
Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis.
British journal of cancer 2009;101(8):1461-8.
2009: D Gareth R Evans; Fiona Lennard; Linda J Pointon; Susan J Ramus; Simon A Gayther; Nayanta Sodha; Gek E Kwan-Lim; Martin Leach; Ruth Warren; Deborah Thompson; Douglas F Easton; Rosalind Eeles
Eligibility for magnetic resonance imaging screening in the United Kingdom: effect of strict selection criteria and anonymous DNA testing on breast cancer incidence in the MARIBS Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(7):2123-31.
2009: K Lawrenson; E Benjamin; Mark Turmaine; Ian Jacobs; Simon A Gayther; D Dafou
In vitro three-dimensional modelling of human ovarian surface epithelial cells.
Cell proliferation 2009;42(3):385-93.
2009: Lydia Quaye; Dimitra Dafou; Susan J Ramus; Honglin Song; Aleksandra Gentry-Maharaj; Aleksandra Gentry Maharaj; Maria Notaridou; Estrid Hogdall; Susanne Kruger Kjaer; Lise Christensen; Claus Hogdall; Douglas F Easton; Ian Jacobs; Usha Menon; Paul D P Pharoah; Simon A Gayther
Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.
Human molecular genetics 2009;18(10):1869-78.
2009: Susan J Ramus; Simon A Gayther
The contribution of BRCA1 and BRCA2 to ovarian cancer.
Molecular oncology 2009;3(2):138-50.
2009: B Grun; E Benjamin; J Sinclair; John Francis Timms; I J Jacobs; Simon A Gayther; D Dafou
Three-dimensional in vitro cell biology models of ovarian and endometrial cancer.
Cell proliferation 2009;42(2):219-28.
2009: Lalarukh Khalique; Ayse Ayhan; John C Whittaker; Naveena Singh; Ian J Jacobs; Simon A Gayther; Susan J Ramus
The clonal evolution of metastases from primary serous epithelial ovarian cancers.
International journal of cancer. Journal international du cancer 2009;124(7):1579-86.
2009: L Quaye; Honglin Song; Susan J Ramus; A Gentry-Maharaj; E Høgdall; Richard A DiCioccio; V McGuire; A H Wu; D J Van Den Berg; Malcolm Pike; E Wozniak; J A Doherty; M A Rossing; R B Ness; K B Moysich; C Høgdall; J Blaakaer; Douglas F Easton; bruce ponder; Ian J Jacobs; Usha Menon; Alice S Whittemore; S Krüger-Kjaer; Celeste L Pearce; Paul D P Pharoah; Simon A Gayther
Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer.
British journal of cancer 2009;100(6):993-1001.
2009: Ellen L Goode; Brooke L Fridley; Robert A Vierkant; Julie M Cunningham; Catherine M Phelan; Stephanie Anderson; David N Rider; Kristin L White; V Shane Pankratz; Honglin Song; Estrid Hogdall; Susanne Krüger Kjaer; Alice S Whittemore; Richard A DiCioccio; Susan J Ramus; Simon A Gayther; Joellen M Schildkraut; Paul P D Pharaoh; Thomas A Sellers
Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(3):935-44.
2009: Kate Lawrenson; Simon A Gayther
Ovarian cancer: a clinical challenge that needs some basic answers.
PLoS medicine 2009;6(2):e25.
2009: Andrew E Teschendorff; Usha Menon; Aleksandra Gentry-Maharaj; Susan J Ramus; Simon A Gayther; Sophia Apostolidou; Allison Jones; Matthias Lechner; Stephan Beck; Ian J Jacobs; Martin Widschwendter
An epigenetic signature in peripheral blood predicts active ovarian cancer.
PloS one 2009;4(12):e8274.
2009: Deborah J Thompson; Martin Leach; Gek Kwan-Lim; Simon A Gayther; Susan J Ramus; Iqbal Warsi; Fiona Lennard; Michael Khazen; Emilie Bryant; Sadie Reed; Caroline R M Boggis; D Gareth Evans; Rosalind A Eeles; Douglas F Easton; Ruth M L Warren
Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study.
Breast cancer research : BCR 2009;11(6):R80.
2009: Lydia Quaye; Jonathan Tyrer; Susan J Ramus; Honglin Song; Eva Wozniak; Richard A DiCioccio; Valerie McGuire; Estrid Høgdall; Claus Høgdall; Jan Blaakaer; Ellen L Goode; Joellen M Schildkraut; Douglas F Easton; Susanne Krüger-Kjaer; Alice S Whittemore; Simon A Gayther; Paul D P Pharoah
Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer.
PloS one 2009;4(6):e5983.
2009: Marie Soegaard; Kirsten Frederiksen; Allan Jensen; Estrid V S Høgdall; Claus K Høgdall; Jan Blaakaer; Susan J Ramus; Simon A Gayther; Susanne Krüger Kjaer
Risk of ovarian cancer in women with first-degree relatives with cancer.
Acta obstetricia et gynecologica Scandinavica 2009;88(4):449-56.
2008: Honglin Song; Thibaud Koessler; Shahana Ahmed; Susan J Ramus; Susanne Krüger Kjaer; Richard A DiCioccio; Eva Wozniak; Estrid Hogdall; Alice S Whittemore; Valerie McGuire; Bruce A J Ponder; Clare Turnbull; Sarah Hines; Nazneen Rahman; Rosalind A Eeles; Douglas F Easton; Simon A Gayther; Alison M Dunning; Paul D P Pharoah
Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.
Cancer research 2008;68(21):8837-42.
2008: Andrea Mann; Estrid Hogdall; Susan J Ramus; Richard A DiCioccio; Claus Hogdall; Lydia Quaye; Valerie McGuire; Alice S Whittemore; Mitul Shah; David Greenberg; Douglas F Easton; Bruce A J Ponder; Susanne Krüger Kjaer; Simon A Gayther; Deborah J Thompson; Paul D P Pharoah; Honglin Song
Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.
European journal of cancer (Oxford, England : 1990) 2008;44(15):2259-65.
2008: Susan J Ramus; Karim Elmasry; Zhiyuan Luo; Alex Gammerman; Karen Lu; Ayse Ayhan; Naveena Singh; W Glenn McCluggage; Ian J Jacobs; John C Whittaker; Simon A Gayther
Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5840-8.
2008: Lydia Quaye; Simon A Gayther; Susan J Ramus; Richard A Di Cioccio; Valerie McGuire; Estrid Hogdall; Claus Hogdall; Jan Blaakr; Douglas F Easton; Bruce A J Ponder; Ian Jacobs; Susanne Kruger Kjaer; Alice S Whittemore; Celeste L Pearce; Paul D P Pharoah; Honglin Song
The effects of common genetic variants in oncogenes on ovarian cancer survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5833-9.
2008: Marie Soegaard; Susanne Kruger Kjaer; Mark Cox; Eva Wozniak; Estrid Høgdall; Claus Høgdall; Jan Blaakaer; Ian J Jacobs; Simon A Gayther; Susan J Ramus
BRCA1 and BRCA2 mutation prevalence and clinical characteristics of a population-based series of ovarian cancer cases from Denmark.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(12):3761-7.
2008: James A Morris; Simon A Gayther; Ian J Jacobs; Christopher Jones
A suite of Perl modules for handling microarray data.
Bioinformatics (Oxford, England) 2008;24(8):1102-3.
2008: Honglin Song; Estrid Hogdall; Susan J Ramus; Richard A DiCioccio; Claus Hogdall; Lydia Quaye; Valerie McGuire; Alice S Whittemore; Mitul Shah; David Greenberg; Douglas F Easton; Susanne Kruger Kjaer; Paul D P Pharoah; Simon A Gayther
Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1090-5.
2008: N Singh; A Ayhan; U Menon; J A Chin Aleong; A Z Faruqi; Simon A Gayther; I J Jacobs
Grading of serous ovarian carcinoma: further evidence of a lack of agreement between conventional grading systems.
Histopathology 2008;52(3):393-5.
2008: James A Morris; Simon A Gayther; Ian J Jacobs; Christopher Jones
A Perl toolkit for LIMS development.
Source code for biology and medicine 2008;3():4.
2007: Jonathan Beesley; Susan J Jordan; Amanda B Spurdle; Honglin Song; Susan J Ramus; Suzanne Kruger Kjaer; Estrid Hogdall; Richard A DiCioccio; Valerie McGuire; Alice S Whittemore; Simon A Gayther; Paul D P Pharoah; Penelope M Webb; Georgia Chenevix-Trench
Association between single-nucleotide polymorphisms in hormone metabolism and DNA repair genes and epithelial ovarian cancer: results from two Australian studies and an additional validation set.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(12):2557-65.
2007: Susan J Ramus; Patricia A Harrington; Carole Pye; Richard A DiCioccio; Mark J Cox; Kim Garlinghouse-Jones; Ingrid Oakley-Girvan; Ian J Jacobs; Richard M Hardy; Alice S Whittemore; Bruce A J Ponder; M Steven Piver; Paul D P Pharoah; Simon A Gayther
Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer.
Human mutation 2007;28(12):1207-15.
2007: Estrid V S Høgdall; Lise Christensen; Claus K Høgdall; Jan Blaakaer; Simon A Gayther; Ian J Jacobs; Ib Jarle Christensen; Susanne Krüger Kjaer
Prognostic value of estrogen receptor and progesterone receptor tumor expression in Danish ovarian cancer patients: from the 'MALOVA' ovarian cancer study.
Oncology reports 2007;18(5):1051-9.
2007: Ningfeng F Li; S Broad; Y J Lu; J S Yang; R Watson; Thorsten Hagemann; George D Wilbanks; I Jacobs; Frances R Balkwill; D Dafou; Simon A Gayther
Human ovarian surface epithelial cells immortalized with hTERT maintain functional pRb and p53 expression.
Cell proliferation 2007;40(5):780-94.
2007: Ali Tiss; Celia Smith; Stephane Camuzeaux; Musarat Kabir; Simon A Gayther; Usha Menon; Michael D Waterfield; John Francis Timms; Ian Jacobs; Rainer Cramer
Serum peptide profiling using MALDI mass spectrometry: avoiding the pitfalls of coated magnetic beads using well-established ZipTip technology.
Proteomics 2007;7 Suppl 1():77-89.
2007: Estrid V S Høgdall; Lise Christensen; Susanne Krüger Kjaer; Jan Blaakaer; Ib Jarle Christensen; Simon A Gayther; Ian J Jacobs; Claus K Høgdall
Expression level of Wilms tumor 1 (WT1) protein has limited prognostic value in epithelial ovarian cancer: from the Danish "MALOVA" ovarian cancer study.
Gynecologic oncology 2007;106(2):318-24.
2007: Susan J Ramus; Patricia A Harrington; Carole Pye; Susan Peock; Margaret R Cook; Mark J Cox; Ian J Jacobs; Richard A DiCioccio; Alice S Whittemore; M Steven Piver; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah; Simon A Gayther
Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis. Mutation in brief #964. Online.
Human mutation 2007;28(5):525-6.
2007: Estrid V S Høgdall; Lise Christensen; Susanne Krüger Kjaer; Jan Blaakaer; Anette Kjaerbye-Thygesen; Simon A Gayther; Ian J Jacobs; Claus K Høgdall
CA125 expression pattern, prognosis and correlation with serum CA125 in ovarian tumor patients. From The Danish "MALOVA" Ovarian Cancer Study.
Gynecologic oncology 2007;104(3):508-15.
2007: L Khalique; A Ayhan; Michael E Weale; Ian J Jacobs; Susan J Ramus; Simon A Gayther
Genetic intra-tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours.
The Journal of pathology 2007;211(3):286-95.
2007: Thorsten Hagemann; T Bozanovic; S Hooper; A Ljubic; V I F Slettenaar; Julia L Wilson; N Singh; Simon A Gayther; John H Shepherd; Philippe O van Trappen
Molecular profiling of cervical cancer progression.
British journal of cancer 2007;96(2):321-8.
2007: Honglin Song; Susan J Ramus; Susanne Krüger Kjaer; Estrid Hogdall; Richard A DiCioccio; Alice S Whittemore; Valerie McGuire; Claus Hogdall; Ian J Jacobs; Douglas F Easton; Bruce A J Ponder; Alison M Dunning; Simon A Gayther; Paul D P Pharoah
Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer.
PloS one 2007;2(3):e268.
2007: Philippe O van Trappen; Tom Cullup; R Troke; D Swann; John H Shepherd; Ian J Jacobs; Simon A Gayther; Charles A Mein
Somatic mitochondrial DNA mutations in primary and metastatic ovarian cancer.
Gynecologic oncology 2007;104(1):129-33.
2006: Honglin Song; Susan J Ramus; Lydia Quaye; Richard A DiCioccio; Jonathan Tyrer; Emma Lomas; Danielle Shadforth; Estrid Hogdall; Claus Hogdall; Valerie McGuire; Alice S Whittemore; Douglas F Easton; Bruce A J Ponder; Susanne Krüger Kjaer; Paul D P Pharoah; Simon A Gayther
Common variants in mismatch repair genes and risk of invasive ovarian cancer.
Carcinogenesis 2006;27(11):2235-42.
2006: Honglin Song; Susan J Ramus; Danielle Shadforth; Lydia Quaye; Susanne Krüger Kjaer; Richard A DiCioccio; Alison M Dunning; Estrid Hogdall; Claus Hogdall; Alice S Whittemore; Valerie McGuire; Fabienne LESUEUR; Douglas F Easton; Ian J Jacobs; Bruce A J Ponder; Simon A Gayther; Paul D P Pharoah
Common variants in RB1 gene and risk of invasive ovarian cancer.
Cancer research 2006;66(20):10220-6.
2006: Karim Elmasry; Simon A Gayther
Ovarian cancer aetiology: facts and fiction.
The journal of family planning and reproductive health care / Faculty of Family Planning & Reproductive Health Care, Royal College of Obstetricians & Gynaecologists 2006;32(2):82-6.
2006: Marie Søgaard; Susanne Krüger Kjaer; Simon A Gayther
Ovarian cancer and genetic susceptibility in relation to the BRCA1 and BRCA2 genes. Occurrence, clinical importance and intervention.
Acta obstetricia et gynecologica Scandinavica 2006;85(1):93-105.
2005: Annika Auranen; Honglin Song; Christy Waterfall; Richard A DiCioccio; Bettina Kuschel; Susanne Krüger Kjaer; Estrid Hogdall; Claus Hogdall; John Stratton; Alice S Whittemore; Douglas F Easton; Bruce A J Ponder; Karen L Novik; Alison M Dunning; Simon A Gayther; Paul D P Pharoah
Polymorphisms in DNA repair genes and epithelial ovarian cancer risk.
International journal of cancer. Journal international du cancer 2005;117(4):611-8.
2004: Dirk Brinkmann; Andy Ryan; Ayse Ayhan; W Glen McCluggage; Roger M Feakins; Mauro F Santibanez-Koref; Charles A Mein; Simon A Gayther; Ian J Jacobs
A molecular genetic and statistical approach for the diagnosis of dual-site cancers.
Journal of the National Cancer Institute 2004;96(19):1441-6.
2004: Richard A DiCioccio; Honglin Song; Christy Waterfall; Makoto T Kimura; Hiroki Nagase; Valerie McGuire; Estrid Hogdall; Mitul N Shah; Robert N Luben; Douglas F Easton; Ian J Jacobs; Bruce A J Ponder; Alice S Whittemore; Simon A Gayther; Paul D P Pharoah; Susan Kruger-Kjaer
STK15 polymorphisms and association with risk of invasive ovarian cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(10):1589-94.
2004: Ningfeng F Li; George D Wilbanks; Frances R Balkwill; Ian J Jacobs; Dimitra Dafou; Simon A Gayther
A modified medium that significantly improves the growth of human normal ovarian surface epithelial (OSE) cells in vitro.
Laboratory investigation; a journal of technical methods and pathology 2004;84(7):923-31.
2004: Bruce A Werness; Susan J Ramus; Richard A DiCioccio; Alice S Whittemore; Kim Garlinghouse-Jones; Ingrid Oakley-Girvan; Yoshiaki Tsukada; Patricia Harrington; Simon A Gayther; Bruce A J Ponder; M Steven Piver
Histopathology, FIGO stage, and BRCA mutation status of ovarian cancers from the Gilda Radner Familial Ovarian Cancer Registry.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2004;23(1):29-34.
2003: Susan J Ramus; Paul D P Pharoah; Patricia Harrington; Carole Pye; Bruce A Werness; Lynda Bobrow; Ayse Ayhan; Dagan Wells; Ami Fishman; Martin Gore; Richard A DiCioccio; M Steven Piver; Alice S Whittemore; Bruce A J Ponder; Simon A Gayther
BRCA1/2 mutation status influences somatic genetic progression in inherited and sporadic epithelial ovarian cancer cases.
Cancer research 2003;63(2):417-23.
2003: Stephen M Edwards; Zsofia Kote-Jarai; Julia Meitz; Rifat A Hamoudi; Questa Hope; Peter Osin; Rachel Jackson; Christine Southgate; Rashmi Singh; Alison Falconer; David P Dearnaley; Audrey Ardern-Jones; Annette Murkin; Anna Dowe; Jo Kelly; Sue Williams; Richard Oram; Margaret Stevens; Dawn M Teare; Bruce A J Ponder; Simon A Gayther; Douglas F Easton; Rosalind A Eeles
Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.
American journal of human genetics 2003;72(1):1-12.
2002: Victoria M Basham; Julian M Lipscombe; Joanna M Ward; Simon A Gayther; Bruce A J Ponder; Douglas F Easton; Paul D P Pharoah
BRCA1 and BRCA2 mutations in a population-based study of male breast cancer.
Breast cancer research : BCR 2002;4(1):R2.
2001: Bettina Kuschel; Simon A Gayther; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah
Apparent human BRCA1 knockout caused by mispriming during polymerase chain reaction: implications for genetic testing.
Genes, chromosomes & cancer 2001;31(1):96-8.
2000: Simon A Gayther; KA de Foy; Patricia Harrington; Paul Pharoah; WD Dunsmuir; Stephen M Edwards; CE Gillett; Audrey Ardern-Jones; David P Dearnaley; Douglas F Easton; D Ford; R J Shearer; RS Kirby; Anna Dowe; Jo Kelly; Michael R Stratton; Bruce A J Ponder; D Barnes; Rosalind A Eeles
The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators.
Cancer research 2000;60(16):4513-8.
2000: P A Russell; Paul D P Pharoah; KA de Foy; Susan J Ramus; I Symmonds; A Wilson; I Scott; Bruce A J Ponder; Simon A Gayther
Frequent loss of BRCA1 mRNA and protein expression in sporadic ovarian cancers.
International journal of cancer. Journal international du cancer 2000;87(3):317-21.
2000: Simon A Gayther; SJ Batley; L Linger; Andrew J Bannister; K Thorpe; Suet-Feung Chin; Yataro Daigo; P Russell; A Wilson; HM Sowter; J D Delhanty; Bruce A J Ponder; Tony Kouzarides; Carlos Caldas
Mutations truncating the EP300 acetylase in human cancers.
Nature genetics 2000;24(3):300-3.
2000: Antonis C Antoniou; Simon A Gayther; JF Stratton; Bruce A J Ponder; Douglas F Easton
Risk models for familial ovarian and breast cancer.
Genetic epidemiology 2000;18(2):173-90.
1999: Carlos Caldas; Fátima Carneiro; H T Lynch; J Yokota; G L Wiesner; S M Powell; Frank R Lewis; David Huntsman; P D Pharoah; Janusz A Jankowski; PM MacLeod; H Vogelsang; G Keller; K G Park; Frances M Richards; Eamonn R Maher; Simon A Gayther; Carla Oliveira; Nicola Grehan; D Wight; Raquel Seruca; franco roviello; Bruce A J Ponder; C E Jackson
Familial gastric cancer: overview and guidelines for management.
Journal of medical genetics 1999;36(12):873-80.
1999: Simon A Gayther; P Russell; Patricia Harrington; Antonis C Antoniou; Douglas F Easton; Bruce A J Ponder
The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes.
American journal of human genetics 1999;65(4):1021-9.
1999: Susan J Ramus; Lynda Bobrow; Paul D P Pharoah; D S Finnigan; Ami Fishman; M Altaras; Patricia A Harrington; Simon A Gayther; Bruce A J Ponder; LS Friedman
Increased frequency of TP53 mutations in BRCA1 and BRCA2 ovarian tumours.
Genes, chromosomes & cancer 1999;25(2):91-6.
1999: Paul D P Pharoah; Douglas F Easton; D L Stockton; Simon A Gayther; Bruce A J Ponder
Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group.
Cancer research 1999;59(4):868-71.
1998: Simon A Gayther; Paul D P Pharoah; Bruce A J Ponder
The genetics of inherited breast cancer.
Journal of mammary gland biology and neoplasia 1998;3(4):365-76.
1998: Simon A Gayther; K L Gorringe; Susan J Ramus; David Huntsman; franco roviello; Nicola Grehan; José Carlos Machado; E Pinto; Raquel Seruca; K Halling; PM MacLeod; S M Powell; C E Jackson; Bruce A J Ponder; Carlos Caldas
Identification of germ-line E-cadherin mutations in gastric cancer families of European origin.
Cancer research 1998;58(18):4086-9.
1998: Simon A Gayther; Bruce A J Ponder
Clues to the function of the tumour susceptibility gene BRCA2.
Disease markers 1998;14(1):1-8.
1998: KA de Foy; Simon A Gayther; W H Colledge; S Crockett; I V Scott; Martin J Evans; Bruce A J Ponder
Mutation analysis of the c-mos proto-oncogene in human ovarian teratomas.
British journal of cancer 1998;77(10):1642-4.
1998: D Ford; Douglas F Easton; Michael Stratton; Steven A Narod; David E Goldgar; Peter Devilee; Tim BISHOP; B Weber; G Lenoir; Jenny Chang-Claude; H Sobol; MD Teare; Jeffery Struewing; Adalgeir Arason; Siegfried Scherneck; Julian Peto; T R Rebbeck; P Tonin; Susan L Neuhausen; Rosa B Barkardottir; Jorunn E Eyfjord; H Lynch; Bruce A J Ponder; Simon A Gayther; M Zelada-Hedman
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
American journal of human genetics 1998;62(3):676-89.
1998: Jon Thor Bergthorsson; A Jonasdottir; Gudrun Johannesdottir; Adalgeir Arason; Valgardur Egilsson; Simon A Gayther; Ake Borg; S Hakanson; Sigurdur Ingvarsson; Rosa B Barkardottir
Identification of a novel splice-site mutation of the BRCA1 gene in two breast cancer families: screening reveals low frequency in Icelandic breast cancer patients.
Human mutation 1998;Suppl 1():S195-7.
1997: Simon A Gayther; P Barski; SJ Batley; L Li; KA de Foy; S N Cohen; Bruce A J Ponder; Carlos Caldas
Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours.
Oncogene 1997;15(17):2119-26.
1997: Susan J Ramus; Zsofia Kote-Jarai; LS Friedman; M van der Looij; Simon A Gayther; B Csokay; Bruce A J Ponder; Edith Olah
Analysis of BRCA1 and BRCA2 mutations in Hungarian families with breast or breast-ovarian cancer.
American journal of human genetics 1997;60(5):1242-6.
1997: Simon A Gayther; Patricia Harrington; P Russell; G Kharkevich; R F Garkavtseva; Bruce A J Ponder
Frequently occurring germ-line mutations of the BRCA1 gene in ovarian cancer families from Russia.
American journal of human genetics 1997;60(5):1239-42.
1997: JF Stratton; Simon A Gayther; P Russell; J Dearden; Martin Gore; P Blake; Douglas Easton; Bruce A J Ponder
Contribution of BRCA1 mutations to ovarian cancer.
The New England journal of medicine 1997;336(16):1125-30.
1997: Simon A Gayther; Bruce A J Ponder
Mutations of the BRCA1 and BRCA2 genes and the possibilities for predictive testing.
Molecular medicine today 1997;3(4):168-74.
1997: LS Friedman; Simon A Gayther; T Kurosaki; D Gordon; B Noble; G Casey; Bruce A J Ponder; H Anton-Culver
Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population.
American journal of human genetics 1997;60(2):313-9.
1997: Simon A Gayther; J Mangion; P Russell; Sheila Seal; Rita Barfoot; Bruce A J Ponder; Michael R Stratton; Douglas Easton
Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene.
Nature genetics 1997;15(1):103-5.
1997: Susan J Ramus; LS Friedman; Simon A Gayther; Bruce A J Ponder; Lynda Bobrow; M van der Looji; Janos Papp; Edith Olah
A breast/ovarian cancer patient with germline mutations in both BRCA1 and BRCA2.
Nature genetics 1997;15(1):14-5.
1996: Sylvie Mazoyer; Alison M Dunning; OM Serova; J Dearden; Nadine Puget; Catherine S Healey; Simon A Gayther; J Mangion; Michael R Stratton; Henry T Lynch; David E Goldgar; Bruce A J Ponder; Gilbert M Lenoir
A polymorphic stop codon in BRCA2.
Nature genetics 1996;14(3):253-4.
1996: K A Foster; Patricia Harrington; J Kerr; P Russell; R A DiCioccio; I V Scott; I Jacobs; G Chenevix-Trench; Bruce A J Ponder; Simon A Gayther
Somatic and germline mutations of the BRCA2 gene in sporadic ovarian cancer.
Cancer research 1996;56(16):3622-5.
1996: Charis Eng; K A Foster; Catherine S Healey; Carol Houghton; Simon A Gayther; Lois M Mulligan; Bruce A J Ponder
Mutation analysis of the c-mos proto-oncogene and the endothelin-B receptor gene in medullary thyroid carcinoma and phaeochromocytoma.
British journal of cancer 1996;74(3):339-41.
1996: Simon A Gayther; Patricia Harrington; P Russell; G Kharkevich; R F Garkavtseva; Bruce A J Ponder
Rapid detection of regionally clustered germ-line BRCA1 mutations by multiplex heteroduplex analysis. UKCCCR Familial Ovarian Cancer Study Group.
American journal of human genetics 1996;58(3):451-6.
1995: Simon A Gayther; W Warren; Sylvie Mazoyer; P A Russell; Patricia Harrington; M Chiano; Sheila Seal; Rifat A Hamoudi; E J van Rensburg; Alison M Dunning; R Love; G Evans; Douglas Easton; D Clayton; Michael R Stratton; Bruce A J Ponder
Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation.
Nature genetics 1995;11(4):428-33.
1995: Sylvie Mazoyer; Simon A Gayther; M A Nagai; S A Smith; Alison M Dunning; E J van Rensburg; H Albertsen; Raymond White; Bruce A J Ponder
A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dIg-A.
Genomics 1995;28(1):25-31.